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Tytuł:
Brolucizumab in recalcitrant neovascular age-related macular degeneration-real-world data in Chinese population.
Autorzy:
Weng CC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Chi SC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.
Lin TC; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Huang YM; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Chou YB; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Hwang DK; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
Chen SJ; Department of Ophthalmology, Taipei Veterans General Hospital, Taipei City, Taiwan.; School of Medicine, National Yang Ming Chiao Tung University, Taipei City, Taiwan.
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Źródło:
PloS one [PLoS One] 2024 Apr 02; Vol. 19 (4), pp. e0301096. Date of Electronic Publication: 2024 Apr 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Detachment*/etiology
Macular Degeneration*/drug therapy
Macular Degeneration*/epidemiology
Macular Degeneration*/complications
Wet Macular Degeneration*/drug therapy
Wet Macular Degeneration*/complications
Antibodies, Monoclonal, Humanized*
Humans ; Aged ; Aged, 80 and over ; Treatment Outcome ; Follow-Up Studies ; Retrospective Studies ; Receptors, Vascular Endothelial Growth Factor/therapeutic use ; Tomography, Optical Coherence ; Visual Acuity ; Intravitreal Injections ; Vision Disorders/complications ; China ; Angiogenesis Inhibitors/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Identification of Genetic Variants for Risk Prediction and Early Diagnosis of Age-Related Macular Degeneration in the Taiwanese Population.
Autorzy:
Huang YC; School of Chinese Medicine, China Medical University, Taichung 404328, Taiwan.; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan.
Liao WL; Center for Personalized Medicine, China Medical University Hospital, Taichung 404327, Taiwan.; Graduate Institute of Integrated Medicine, China Medical University, Taichung 404328, Taiwan.
Lin HJ; School of Chinese Medicine, China Medical University, Taichung 404328, Taiwan.; Department of Ophthalmology, China Medical University Hospital, Taichung 404327, Taiwan.
Huang YT; Department of Ophthalmology, China Medical University Hospital, Taichung 404327, Taiwan.
Chang YW; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan.
Liu TY; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan.
Chen YC; Million-Person Precision Medicine Initiative, Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan.
Weng AL; American School in Taichung, Taichung 406051, Taiwan.
Tsai FJ; School of Chinese Medicine, China Medical University, Taichung 404328, Taiwan.; Genetic Center, Department of Medical Research, China Medical University Hospital, Taichung 404327, Taiwan.; Department of Medical Genetics, China Medical University Hospital, Taichung 404327, Taiwan.; Children's Hospital of China Medical University, Taichung 404327, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 12; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 12.
Typ publikacji:
Journal Article
MeSH Terms:
Proteins*/genetics
Macular Degeneration*/diagnosis
Macular Degeneration*/epidemiology
Macular Degeneration*/genetics
Aged ; Humans ; Genome-Wide Association Study ; High-Temperature Requirement A Serine Peptidase 1/genetics ; Polymorphism, Single Nucleotide ; Early Diagnosis ; Genetic Predisposition to Disease ; Risk Factors ; Genotype
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Treatment Strategies for Anti-VEGF Resistance in Neovascular Age-Related Macular Degeneration by Targeting Arteriolar Choroidal Neovascularization.
Autorzy:
Fu Y; Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.; Department of Neuroscience, Baylor College of Medicine, Houston, TX 77030, USA.
Zhang Z; Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.
Webster KA; Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA.; Vascular Biology Institute, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
Paulus YM; Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor, MI 48105, USA.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI 48105, USA.
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Źródło:
Biomolecules [Biomolecules] 2024 Feb 21; Vol. 14 (3). Date of Electronic Publication: 2024 Feb 21.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Macular Degeneration*/drug therapy
Macular Degeneration*/metabolism
Choroidal Neovascularization*/drug therapy
Animals ; Humans ; Angiogenesis Inhibitors/pharmacology ; Angiogenesis Inhibitors/therapeutic use ; Vascular Endothelial Growth Factor A ; Vascular Endothelial Growth Factors ; Cholesterol
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A New Generation of Gene Therapies as the Future of Wet AMD Treatment.
Autorzy:
Blasiak J; Faculty of Medicine, Collegium Medicum, Mazovian Academy in Plock, 09-402 Plock, Poland.
Pawlowska E; Department of Pediatric Dentistry, Medical University of Lodz, 92-217 Lodz, Poland.
Ciupińska J; Clinical Department of Infectious Diseases and Hepatology, H. Bieganski Hospital, 91-347 Lodz, Poland.
Derwich M; Department of Pediatric Dentistry, Medical University of Lodz, 92-217 Lodz, Poland.
Szczepanska J; Department of Pediatric Dentistry, Medical University of Lodz, 92-217 Lodz, Poland.
Kaarniranta K; Department of Ophthalmology, University of Eastern Finland, 70210 Kuopio, Finland.; Department of Ophthalmology, Kuopio University Hospital, 70210 Kuopio, Finland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Feb 17; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 17.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Vascular Endothelial Growth Factor A*
Wet Macular Degeneration*/therapy
Wet Macular Degeneration*/drug therapy
Humans ; Genetic Therapy ; Angiogenesis Inhibitors/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Retinal pigment epithelium rip with posterior uveitis after intravitreal brolucizumab in neovascular age-related macular degeneration.
Autorzy:
Dabir S; Department of Retina and Vitreous, Rajan Eye Care Hospital Pvt Ltd., 5, Vidyodaya Second Street, T. Nagar, Chennai, Tamil Nadu, India.
Mohankumar A
Rao VP
Rajan M
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Źródło:
Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Feb 01; Vol. 72 (2), pp. 292-294. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Uveitis, Posterior*/diagnosis
Uveitis, Posterior*/drug therapy
Macular Degeneration*
Wet Macular Degeneration*/diagnosis
Wet Macular Degeneration*/drug therapy
Humans ; Retinal Pigment Epithelium ; Antibodies, Monoclonal, Humanized/adverse effects ; Intravitreal Injections ; Angiogenesis Inhibitors/therapeutic use
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Understanding the Impact of Polyunsaturated Fatty Acids on Age-Related Macular Degeneration: A Review.
Autorzy:
Brito M; Unither Développement Bordeaux, Avenue Toussaint Catros, 33185 Le Haillan, France.; Université Paris Cité, CNRS, INSERM, UTCBS, Unité de Technologies Chimiques et Biologiques pour la Santé, F-75006 Paris, France.; Département de Recherche et Développement (DRDP), Agence Générale des Equipements et Produits de Santé (AGEPS), Assistance Publique Hôpitaux de Paris (AP-HP), 7 Rue du Fer-à-Moulin, 75005 Paris, France.; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1206 Geneva, Switzerland.
Sorbier C; Unither Développement Bordeaux, Avenue Toussaint Catros, 33185 Le Haillan, France.
Mignet N; Université Paris Cité, CNRS, INSERM, UTCBS, Unité de Technologies Chimiques et Biologiques pour la Santé, F-75006 Paris, France.
Boudy V; Université Paris Cité, CNRS, INSERM, UTCBS, Unité de Technologies Chimiques et Biologiques pour la Santé, F-75006 Paris, France.; Département de Recherche et Développement (DRDP), Agence Générale des Equipements et Produits de Santé (AGEPS), Assistance Publique Hôpitaux de Paris (AP-HP), 7 Rue du Fer-à-Moulin, 75005 Paris, France.
Borchard G; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1206 Geneva, Switzerland.
Vacher G; Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), School of Pharmaceutical Sciences, University of Geneva, Rue Michel-Servet 1, 1206 Geneva, Switzerland.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 07; Vol. 25 (7). Date of Electronic Publication: 2024 Apr 07.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Wet Macular Degeneration*
Fatty Acids, Omega-3*/therapeutic use
Geographic Atrophy*
Humans ; Fatty Acids, Unsaturated/therapeutic use ; Fatty Acids
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Wnt5a/β-catenin-mediated epithelial-mesenchymal transition: a key driver of subretinal fibrosis in neovascular age-related macular degeneration.
Autorzy:
Liu D; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Du J; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China.
Xie H; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China.
Tian H; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Lu L; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China.
Zhang C; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China. .
Xu GT; Department of Ophthalmology of Tongji Hospital and Laboratory of Clinical and Visual Sciences of Tongji Eye Institute, School of Medicine, Tongji University, Shanghai, China. .
Zhang J; Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China. .; Shanghai Key Laboratory of Ocular Fundus Diseases, National Clinical Research Center for Eye Diseases, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai Engineering Center for Precise Diagnosis and Treatment of Eye Diseases, Shanghai Eye Research Institute, Shanghai, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 26; Vol. 21 (1), pp. 75. Date of Electronic Publication: 2024 Mar 26.
Typ publikacji:
Journal Article
MeSH Terms:
beta Catenin*/metabolism
Macular Degeneration*/metabolism
Sulfonamides*
Humans ; Male ; Animals ; Mice ; Wnt-5a Protein ; Mice, Inbred C57BL ; Retinal Pigment Epithelium/metabolism ; Epithelial-Mesenchymal Transition ; Fibrosis ; RNA, Small Interfering/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Eye Drop with Fas-Blocking Peptide Attenuates Age-Related Macular Degeneration.
Autorzy:
Yi Y; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Pyun SH; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Kim CY; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Yun G; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Kang E; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Heo S; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
Ullah I; Department of Internal Medicine, Yale University, New Haven, CT 06520, USA.
Lee SK; Department of Bioengineering and Institute of Nanoscience and Technology, Hanyang University, Seoul 04763, Republic of Korea.
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Źródło:
Cells [Cells] 2024 Mar 20; Vol. 13 (6). Date of Electronic Publication: 2024 Mar 20.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*
Macular Degeneration*/metabolism
Humans ; Mice ; Animals ; Rabbits ; Ophthalmic Solutions/therapeutic use ; Peptides/therapeutic use ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The contribution of pattern recognition receptor signalling in the development of age related macular degeneration: the role of toll-like-receptors and the NLRP3-inflammasome.
Autorzy:
Brandli A; Department of Anatomy and Physiology, The University of Melbourne, Grattan St, Parkville, Victoria, 3010, Australia.; Roche Pharma Research and Early Development, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
Vessey KA; Department of Anatomy and Physiology, The University of Melbourne, Grattan St, Parkville, Victoria, 3010, Australia.
Fletcher EL; Department of Anatomy and Physiology, The University of Melbourne, Grattan St, Parkville, Victoria, 3010, Australia. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 05; Vol. 21 (1), pp. 64. Date of Electronic Publication: 2024 Mar 05.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Inflammasomes*
Macular Degeneration*
Animals ; NLR Family, Pyrin Domain-Containing 3 Protein ; Toll-Like Receptors ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Using the Amsler Grid Test for Age-Related Macular Degeneration Screening.
Autorzy:
Kuzucu Üşümüş SA; University of Health Sciences Türkiye, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Clinic of Family Medicine, Ankara, Türkiye.
Koçak Altıntaş AG; University of Health Sciences Türkiye, Ulucanlar Eye Training and Research Hospital, Clinic of Ophthalmology, Ankara, Türkiye.
Özdemir A; University of Health Sciences Türkiye, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Clinic of Family Medicine, Ankara, Türkiye.
Aypak C; University of Health Sciences Türkiye, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Clinic of Family Medicine, Ankara, Türkiye.
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Źródło:
Turkish journal of ophthalmology [Turk J Ophthalmol] 2024 Feb 22; Vol. 54 (1), pp. 11-16.
Typ publikacji:
Journal Article
MeSH Terms:
Visual Field Tests*/methods
Macular Degeneration*/diagnosis
Humans ; Middle Aged ; Aged ; Visual Acuity ; Sensitivity and Specificity ; Tomography, Optical Coherence
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Ocular syphilis masquerading as refractory retinal diseases.
Autorzy:
Park SW; Department of Ophthalmology, School of Medicine, Pusan National University, Busan, South Korea.; Medical Research Institute, School of Medicine, Pusan National University Hospital, Busan, South Korea.; Spencer Center for Vision Research, Byers Eye Institute, Stanford University, 2370 Watson Court, Suite 200, Palo Alto, CA, 94303, USA.
Kim KH; Department of Infection, School of Medicine, Pusan National University, Busan, South Korea.
Kwon HJ; Department of Ophthalmology, School of Medicine, Pusan National University, Busan, South Korea.; Medical Research Institute, School of Medicine, Pusan National University Hospital, Busan, South Korea.
Byon IS; Department of Ophthalmology, School of Medicine, Pusan National University, Busan, South Korea.; Medical Research Institute, School of Medicine, Pusan National University Hospital, Busan, South Korea.
Khan YH; Spencer Center for Vision Research, Byers Eye Institute, Stanford University, 2370 Watson Court, Suite 200, Palo Alto, CA, 94303, USA.
Nguyen QD; Spencer Center for Vision Research, Byers Eye Institute, Stanford University, 2370 Watson Court, Suite 200, Palo Alto, CA, 94303, USA. .
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Źródło:
BMC infectious diseases [BMC Infect Dis] 2024 Feb 07; Vol. 24 (1), pp. 165. Date of Electronic Publication: 2024 Feb 07.
Typ publikacji:
Journal Article
MeSH Terms:
Diabetic Retinopathy*/drug therapy
Macular Edema*
Syphilis*/diagnosis
Syphilis*/drug therapy
Choroidal Neovascularization*/diagnosis
Choroidal Neovascularization*/drug therapy
Wet Macular Degeneration*/drug therapy
Endophthalmitis*/drug therapy
Humans ; Angiogenesis Inhibitors/therapeutic use ; Vascular Endothelial Growth Factor A ; Visual Acuity ; Intravitreal Injections
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessment of vision-related quality of life and depression in patients with age-related macular degeneration.
Autorzy:
Dogan L; Kilis State Hospital, Department of Ophthalmology, Kilis, Turkey.
Tanriverdi D; Gaziantep University, Faculty of Health Sciences, Department of Psychiatric Nursing Gaziantep, Turkey.
Gungor K; Gaziantep University Hospital Ophthalmology Department, Gaziantep, Turkey.
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Źródło:
Indian journal of ophthalmology [Indian J Ophthalmol] 2024 Feb 01; Vol. 72 (Suppl 2), pp. S293-S297. Date of Electronic Publication: 2024 Jan 25.
Typ publikacji:
Journal Article
MeSH Terms:
Quality of Life*
Macular Degeneration*/complications
Macular Degeneration*/diagnosis
Macular Degeneration*/epidemiology
Male ; Humans ; Female ; Aged ; Cross-Sectional Studies ; Depression/diagnosis ; Depression/epidemiology ; Depression/etiology ; Visual Acuity ; Surveys and Questionnaires
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulatory T cells limit age-associated retinal inflammation and neurodegeneration.
Autorzy:
Llorián-Salvador M; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK.; Vall d'Hebron Research Institute (VHIR), Universitat Autónoma de Barcelona, 08035, Barcelona, Spain.
de Fuente AG; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK. .; Institute for Health and Biomedical Research of Alicante (ISABIAL) Alicante, 03010, Alicante, Spain. .; Instituto de Neurociencias CSIC-UMH, San Juan de Alicante, 03550, Alicante, Spain. .
McMurran CE; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden.
Dashwood A; Babraham Institute, Cambridge, UK.; Department of Pathology, University of Cambridge, Cambridge, UK.
Dooley J; Department of Pathology, University of Cambridge, Cambridge, UK.
Liston A; Department of Pathology, University of Cambridge, Cambridge, UK.
Penalva R; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK.
Dombrowski Y; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK.
Stitt AW; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK. .
Fitzgerald DC; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, Northern Ireland, BT9 7BL, UK.
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Źródło:
Molecular neurodegeneration [Mol Neurodegener] 2024 Apr 05; Vol. 19 (1), pp. 32. Date of Electronic Publication: 2024 Apr 05.
Typ publikacji:
Journal Article
MeSH Terms:
T-Lymphocytes, Regulatory*
Macular Degeneration*
Mice ; Animals ; Gliosis ; Retina ; Inflammation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Assessing fall risk and equilibrium function in patients with age-related macular degeneration and glaucoma: An observational study.
Autorzy:
Tokunaga T; Otorhinolaryngology, Shinseikai Toyama Hospital, Imizu, Japan.
Takegawa R; Otorhinolaryngology, Shinseikai Toyama Hospital, Imizu, Japan.
Ueta Y; Ophthalmology, Shinseikai Toyama Hospital, Imizu, Japan.
Manabe Y; Otorhinolaryngology, Shinseikai Toyama Hospital, Imizu, Japan.
Fushiki H; Otolaryngology, Mejiro University Ear Institute Clinic, Saitama, Japan.
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Źródło:
PloS one [PLoS One] 2024 Apr 01; Vol. 19 (4), pp. e0301377. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
Typ publikacji:
Observational Study; Journal Article
MeSH Terms:
Glaucoma*/complications
Macular Degeneration*/pathology
Humans ; Aged ; Middle Aged ; Dizziness/complications ; Visual Acuity ; Visual Fields ; Scotoma
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Unveiling Drivers of Retinal Degeneration in RCS Rats: Functional, Morphological, and Molecular Insights.
Autorzy:
Ahluwalia K; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Du Z; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.
Martinez-Camarillo JC; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Naik A; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Thomas BB; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Pollalis D; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Lee SY; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.; Department of Physiology & Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA.
Dave P; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Zhou E; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Li Z; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Chester C; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.
Humayun MS; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.; Roski Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA.
Louie SG; Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, Los Angeles, CA 90089, USA.; USC Ginsburg Institute of for Biomedical Therapeutics, University of Southern California, Los Angeles, CA 90033, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Degeneration*
Macular Degeneration*
Retinitis Pigmentosa*
Surgeons*
Humans ; Adult ; Animals ; Rats ; Retina
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Disease-Causing TIMP3 Variants and Deep Phenotyping of Two Czech Families with Sorsby Fundus Dystrophy Associated with Novel p.(Tyr152Cys) Mutation.
Autorzy:
Vergaro A; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Pankievic M; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Jedlickova J; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Dudakova L; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.
Vajter M; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Michaelides M; UCL Institute of Ophthalmology, University College London and Moorfields Eye Hospital, London EC1V 9EL, UK.
Meliska M; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Nemec P; Department of Ophthalmology, First Faculty of Medicine and Military University Hospital Prague, 162 00 Prague, Czech Republic.
Babincova D; Laboratory of Molecular Biology, AGEL, 741 01 Nový Jíčín, Czech Republic.
Kousal B; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Liskova P; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 121 08 Prague, Czech Republic.; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 27; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 27.
Typ publikacji:
Journal Article
MeSH Terms:
Macular Degeneration*
Choroidal Neovascularization*
Humans ; Czech Republic ; Eye ; Mutation ; Tissue Inhibitor of Metalloproteinase-3/genetics
SCR Disease Name:
Fundus Dystrophy, Pseudoinflammatory, Of Sorsby
Czasopismo naukowe
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Tytuł:
The mouse retinal pigment epithelium mounts an innate immune defense response following retinal detachment.
Autorzy:
Abcouwer SF; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA. .
Miglioranza Scavuzzi B; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Kish PE; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Kong D; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Shanmugam S; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Le XA; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Yao J; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Hager H; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
Zacks DN; Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, University of Michigan Medicine, 1000 Wall Street, Ann Arbor, MI, 48105, USA.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 Mar 25; Vol. 21 (1), pp. 74. Date of Electronic Publication: 2024 Mar 25.
Typ publikacji:
Journal Article
MeSH Terms:
Retinal Detachment*/metabolism
Macular Degeneration*/metabolism
Mice ; Animals ; Humans ; Retinal Pigment Epithelium/metabolism ; Retina/metabolism ; Phagocytosis/genetics ; Bone Morphogenetic Protein Receptors/metabolism
Czasopismo naukowe
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Tytuł:
Towards Uncovering the Role of Incomplete Penetrance in Maculopathies through Sequencing of 105 Disease-Associated Genes.
Autorzy:
Hitti-Malin RJ; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Panneman DM; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Corradi Z; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Boonen EGM; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Astuti G; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Dhaenens CM; Univ. Lille, Inserm, CHU Lille, U1172-LilNCog-Lille Neuroscience & Cognition, F-59000 Lille, France.
Stöhr H; Institute of Human Genetics, University of Regensburg, 93053 Regensburg, Germany.
Weber BHF; Institute of Human Genetics, University of Regensburg, 93053 Regensburg, Germany.; Institute of Clinical Human Genetics, University Hospital Regensburg, 93053 Regensburg, Germany.
Sharon D; Department of Ophthalmology, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Banin E; Department of Ophthalmology, Hadassah Medical Center, Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem 91120, Israel.
Karali M; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.
Banfi S; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', 80138 Naples, Italy.; Eye Clinic, Multidisciplinary Department of Medical, Surgical and Dental Sciences, University of Campania 'Luigi Vanvitelli', 80131 Naples, Italy.; Telethon Institute of Genetics and Medicine (TIGEM), 80078 Pozzuoli, Italy.
Ben-Yosef T; Ruth and Bruce Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel.
Glavač D; Department of Molecular Genetics, Institute of Pathology, Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.; Center for Human Genetics and Pharmacogenomics, Faculty of Medicine, University of Maribor, 2000 Maribor, Slovenia.
Farrar GJ; The School of Genetics and Microbiology, The University of Dublin Trinity College, D02 VF25 Dublin, Ireland.
Ayuso C; Department of Genetics, Health Research Institute-Fundación Jiménez Díaz University Hospital, Universidad Autónoma de Madrid (IIS-FJD, UAM), 28049 Madrid, Spain.; Center for Biomedical Network Research on Rare Diseases (CIBERER), Instituto de Salud Carlos III, 28029 Madrid, Spain.
Liskova P; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Dudakova L; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Vajter M; Department of Paediatrics and Inherited Metabolic Disorders, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.; Department of Ophthalmology, First Faculty of Medicine, Charles University and General University Hospital in Prague, 128 08 Prague, Czech Republic.
Ołdak M; Department of Histology and Embryology, Medical University of Warsaw, 02-004 Warsaw, Poland.
Szaflik JP; Department of Ophthalmology, Medical University of Warsaw, SPKSO Ophthalmic University Hospital, 03-709 Warsaw, Poland.
Matynia A; College of Optometry, University of Houston, Houston, TX 77004, USA.; Jules Stein Eye Institute, Los Angeles, CA 90095, USA.; Ophthalmology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA 90095, USA.
Gorin MB; Jules Stein Eye Institute, Los Angeles, CA 90095, USA.
Kämpjärvi K; Blueprint Genetics, 02150 Espoo, Finland.
Bauwens M; Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium.; Center for Medical Genetics, Ghent University Hospital, 9000 Ghent, Belgium.
De Baere E; Department of Biomolecular Medicine, Ghent University, 9000 Ghent, Belgium.; Center for Medical Genetics, Ghent University Hospital, 9000 Ghent, Belgium.
Hoyng CB; Department of Ophthalmology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Li CHZ; Department of Ophthalmology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Klaver CCW; Department of Ophthalmology, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.
Inglehearn CF; Division of Molecular Medicine, Leeds Institute of Medical Research, St. James's University Hospital, University of Leeds, Leeds LS9 7TF, UK.
Fujinami K; Department of Ophthalmology, The Jikei University School of Medicine, Tokyo 105-8461, Japan.
Rivolta C; Institute of Molecular and Clinical Ophthalmology Basel, 4031 Basel, Switzerland.
Allikmets R; Department of Ophthalmology, Columbia University, New York, NY 10027, USA.; Department of Pathology & Cell Biology, Columbia University, New York, NY 10027, USA.
Zernant J; Department of Ophthalmology, Columbia University, New York, NY 10027, USA.
Lee W; Department of Ophthalmology, Columbia University, New York, NY 10027, USA.
Podhajcer OL; Laboratorio de Terapia Molecular y Celular (Genocan), Fundación Instituto Leloir, CONICET, Buenos Aires 1405, Argentina.
Fakin A; Eye Hospital, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
Sajovic J; Eye Hospital, University Medical Centre Ljubljana, 1000 Ljubljana, Slovenia.; Faculty of Medicine, University of Ljubljana, 1000 Ljubljana, Slovenia.
AlTalbishi A; St John of Jerusalem Eye Hospital Group, East Jerusalem 91198, Palestine.
Valeina S; Department of Ophthalmology, Riga Stradins University, LV-1007 Riga, Latvia.; Children's Clinical University Hospital, LV-1004 Riga, Latvia.
Taurina G; Children's Clinical University Hospital, LV-1004 Riga, Latvia.
Vincent AL; Department of Ophthalmology, New Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of Auckland, Grafton, Auckland 1023, New Zealand.; Eye Department, Greenlane Clinical Centre, Auckland District Health Board, Auckland 1142, New Zealand.
Roberts L; University of Cape Town/MRC Precision and Genomic Medicine Research Unit, Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Ramesar R; University of Cape Town/MRC Precision and Genomic Medicine Research Unit, Division of Human Genetics, Department of Pathology, Institute of Infectious Disease and Molecular Medicine (IDM), Faculty of Health Sciences, University of Cape Town, Cape Town 7925, South Africa.
Sartor G; Department of Pharmacy and Biotechnology, University of Bologna, 40127 Bologna, Italy.
Luppi E; Department of Medical and Surgical Sciences, University of Bologna, 40127 Bologna, Italy.; Unit of Medical Genetics, IRCCS Azienda Ospedaliero-Universitaria di Bologna, 40138 Bologna, Italy.
Downes SM; Nuffield Laboratory of Ophthalmology, Nuffield Department of Clinical Neurosciences, Oxford University, Oxford OX3 9DU, UK.; Oxford Eye Hospital, Oxford University NHS Foundation Trust, Oxford OX3 9DU, UK.
van den Born LI; The Rotterdam Eye Hospital, 3011 BH Rotterdam, The Netherlands.
McLaren TL; Australian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.; Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, WA 6009, Australia.
De Roach JN; Australian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.; Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, WA 6009, Australia.
Lamey TM; Australian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.; Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, WA 6009, Australia.
Thompson JA; Australian Inherited Retinal Disease Registry and DNA Bank, Department of Medical Technology and Physics, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia.
Chen FK; Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, WA 6009, Australia.
Tracewska AM; Datana Solutions, 54-530 Wroclaw, Poland.
Kamakari S; Ophthalmic Genetics Unit, OMMA Ophthalmological Institute of Athens, 115 25 Athens, Greece.
Sallum JMF; Department of Ophthalmology and Visual Sciences, Universidade Federal de São Paulo, São Paulo 04023-062, SP, Brazil.; Instituto de Genética Ocular, São Paulo 04552-050, SP, Brazil.
Bolz HJ; Institute of Human Genetics, University Hospital of Cologne, 50937 Cologne, Germany.
Kayserili H; Department of Medical Genetics, Koc University School of Medicine (KUSOM), 34450 Istanbul, Turkey.
Roosing S; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
Cremers FPM; Department of Human Genetics, Radboud University Medical Center, 6500 HB Nijmegen, The Netherlands.
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Źródło:
Biomolecules [Biomolecules] 2024 Mar 19; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
Macular Degeneration*/genetics
Humans ; Mutation ; Penetrance ; Pedigree ; Retina ; Phenotype ; ATP-Binding Cassette Transporters/genetics ; Eye Proteins ; Cadherin Related Proteins ; Nerve Tissue Proteins/genetics
Czasopismo naukowe
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Tytuł:
RAR Inhibitors Display Photo-Protective and Anti-Inflammatory Effects in A2E Stimulated RPE Cells In Vitro through Non-Specific Modulation of PPAR or RXR Transactivation.
Autorzy:
Fontaine V; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Boumedine T; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Monteiro E; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Fournié M; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Gersende G; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Sahel JA; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.; Fondation Ophtalmologique Rothschild, 29 rue Manin, 75019 Paris, France.; Department of Ophthalmology, The University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
Picaud S; Sorbonne Université, INSERM, CNRS, Institut de la Vision, 17 Rue Moreau, 75012 Paris, France.
Veillet S; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
Lafont R; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
Latil M; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
Dilda PJ; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
Camelo S; Biophytis, Sorbonne Université, BC9, 4 place Jussieu, 75005 Paris, France.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 06; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 06.
Typ publikacji:
Journal Article
MeSH Terms:
Carotenoids*
Macular Degeneration*/metabolism
para-Aminobenzoates*
Peroxisome Proliferator-Activated Receptors*/metabolism
Quinolines*
Anti-Inflammatory Agents ; Drug Inverse Agonism ; Inflammation ; Retinoic Acid Receptor alpha/metabolism ; Retinoid X Receptors/metabolism ; Retinoids/metabolism ; Transcriptional Activation ; Vascular Endothelial Growth Factor A/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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