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Tytuł :
Highly synergistic antimicrobial activity of magainin 2 and PGLa peptides is rooted in the formation of supramolecular complexes with lipids.
Autorzy :
Aisenbrey C; Institut de Chimie UMR7177, CNRS, University of Strasbourg, 1, rue Blaise Pascal, 67000, Strasbourg, France. .
Amaro M; J. Heyrovský Institute of Physical Chemistry, v.v.i, Czech Academy of Sciences, Dolejškova 2155/3, 182 23, Prague, Czech Republic. .
Pospíšil P; J. Heyrovský Institute of Physical Chemistry, v.v.i, Czech Academy of Sciences, Dolejškova 2155/3, 182 23, Prague, Czech Republic.; Institut für Angewandte Physik and Center for Functional Nanostructures (CFN), Karlsruhe Institute of Technology, Wolfgang-Gaede-Straße 1, 76131, Karlsruhe, Germany.
Hof M; J. Heyrovský Institute of Physical Chemistry, v.v.i, Czech Academy of Sciences, Dolejškova 2155/3, 182 23, Prague, Czech Republic.
Bechinger B; Institut de Chimie UMR7177, CNRS, University of Strasbourg, 1, rue Blaise Pascal, 67000, Strasbourg, France.; Institut Universitaire de France, Paris, France.
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Źródło :
Scientific reports [Sci Rep] 2020 Jul 15; Vol. 10 (1), pp. 11652. Date of Electronic Publication: 2020 Jul 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Antimicrobial Cationic Peptides/*chemistry
Cell Membrane/*chemistry
Ethanolamines/*chemistry
Magainins/*chemistry
Phosphatidylcholines/*chemistry
Xenopus Proteins/*chemistry
Animals ; Anti-Bacterial Agents/isolation & purification ; Anti-Bacterial Agents/pharmacology ; Antimicrobial Cationic Peptides/isolation & purification ; Antimicrobial Cationic Peptides/pharmacology ; Boron Compounds/chemistry ; Cell Membrane/drug effects ; Drug Combinations ; Drug Synergism ; Fluorescent Dyes/chemistry ; Lipid Bilayers/chemistry ; Magainins/isolation & purification ; Magainins/pharmacology ; Phosphatidylethanolamines/chemistry ; Phosphatidylglycerols/chemistry ; Protein Binding ; Skin/chemistry ; Spectrometry, Fluorescence ; Xenopus Proteins/isolation & purification ; Xenopus Proteins/pharmacology ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Heterodimer and pore formation of magainin 2 and PGLa: The anchoring and tilting of peptides in lipid bilayers.
Autorzy :
Lee H; Department of Chemical Engineering, Dankook University, Yongin, 16890, South Korea. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Jul 01; Vol. 1862 (7), pp. 183305. Date of Electronic Publication: 2020 Apr 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antimicrobial Cationic Peptides/*chemistry
Cell Membrane/*chemistry
Lipid Bilayers/*chemistry
Magainins/*chemistry
Amino Acid Sequence/genetics ; Antimicrobial Cationic Peptides/genetics ; Cell Membrane/genetics ; Dimerization ; Humans ; Magainins/genetics ; Phospholipids/chemistry ; Phospholipids/genetics ; Porosity
Czasopismo naukowe
Tytuł :
Qualitative and Quantitative Changes to Escherichia coli during Treatment with Magainin 2 Observed in Native Conditions by Atomic Force Microscopy.
Autorzy :
Overton K; Department of Biology , Cottey College , 1000 West Austin Boulevard , Nevada , Missouri 64772 , United States.
Greer HM; Department of Biology , Cottey College , 1000 West Austin Boulevard , Nevada , Missouri 64772 , United States.
Ferguson MA; Department of Chemistry , State University of New York , 1 Hawk Drive , New Paltz , New York 12561 , United States.
Spain EM; Department of Chemistry , Occidental College , 1600 Campus Road , Los Angeles , California 90041 , United States.
Elmore DE; Department of Chemistry and Program in Biochemistry , Wellesley College , 106 Central Street , Wellesley , Massachusetts 02481 , United States.
Núñez ME; Department of Chemistry and Program in Biochemistry , Wellesley College , 106 Central Street , Wellesley , Massachusetts 02481 , United States.
Volle CB; Department of Biology , Cottey College , 1000 West Austin Boulevard , Nevada , Missouri 64772 , United States.
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Źródło :
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2020 Jan 21; Vol. 36 (2), pp. 650-659. Date of Electronic Publication: 2020 Jan 08.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Escherichia coli/*drug effects
Magainins/*pharmacology
Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Magainins/chemical synthesis ; Magainins/chemistry ; Microbial Sensitivity Tests ; Microscopy, Atomic Force
Czasopismo naukowe
Tytuł :
Study of molecular transport through a single nanopore in the membrane of a giant unilamellar vesicle using COMSOL simulation.
Autorzy :
Karal MAS; Department of Physics, Bangladesh University of Engineering and Technology, Dhaka, 1000, Bangladesh. .
Islam MK; Department of Physics, Bangladesh University of Engineering and Technology, Dhaka, 1000, Bangladesh.
Mahbub ZB; Department of Mathematics and Physics, North South University, Dhaka, 1229, Bangladesh.
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Źródło :
European biophysics journal : EBJ [Eur Biophys J] 2020 Jan; Vol. 49 (1), pp. 59-69. Date of Electronic Publication: 2019 Dec 04.
Typ publikacji :
Journal Article
MeSH Terms :
Nanopores*
Magainins/*metabolism
Unilamellar Liposomes/*chemistry
Cell Membrane/drug effects ; Cell Membrane/metabolism ; Computer Simulation ; Fluoresceins/metabolism ; Fluorescent Dyes/metabolism ; Magainins/pharmacology ; Unilamellar Liposomes/metabolism ; Xanthenes/metabolism
Czasopismo naukowe
Tytuł :
Effect of membrane potential on pore formation by the antimicrobial peptide magainin 2 in lipid bilayers.
Autorzy :
Rashid MMO; Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan.
Moghal MMR; Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan.
Billah MM; Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan.
Hasan M; Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan.
Yamazaki M; Integrated Bioscience Section, Graduate School of Science and Technology, Shizuoka University, Shizuoka 422-8529, Japan; Nanomaterials Research Division, Research Institute of Electronics, Shizuoka University, Shizuoka 422-8529, Japan; Department of Physics, Faculty of Science, Shizuoka University, Shizuoka 422-8529, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Biomembranes [Biochim Biophys Acta Biomembr] 2020 Oct 01; Vol. 1862 (10), pp. 183381. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Bilayers*
Anti-Bacterial Agents/*pharmacology
Magainins/*pharmacology
Membrane Potentials/*drug effects
Fluorescent Dyes/chemistry ; Unilamellar Liposomes/chemistry
Czasopismo naukowe
Tytuł :
Grafted Polymer Coatings Enhance Fouling Inhibition by an Antimicrobial Peptide on Reverse Osmosis Membranes.
Autorzy :
Shtreimer Kandiyote N; Department of Desalination and Water Treatment , Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev , Sede-Boqer Campus, 8499000 Midreshet Ben Gurion , Israel.
Avisdris T; Department of Desalination and Water Treatment , Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev , Sede-Boqer Campus, 8499000 Midreshet Ben Gurion , Israel.
Arnusch CJ; Department of Desalination and Water Treatment , Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev , Sede-Boqer Campus, 8499000 Midreshet Ben Gurion , Israel.
Kasher R; Department of Desalination and Water Treatment , Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research, Ben-Gurion University of the Negev , Sede-Boqer Campus, 8499000 Midreshet Ben Gurion , Israel.
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Źródło :
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2019 Feb 05; Vol. 35 (5), pp. 1935-1943. Date of Electronic Publication: 2018 Dec 31.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membranes, Artificial*
Anti-Bacterial Agents/*pharmacology
Biofouling/*prevention & control
Magainins/*pharmacology
Polymethacrylic Acids/*chemistry
Xenopus Proteins/*pharmacology
Animals ; Anti-Bacterial Agents/chemistry ; Biofilms/drug effects ; Click Chemistry ; Magainins/chemistry ; Osmosis ; Polymethacrylic Acids/chemical synthesis ; Pseudomonas aeruginosa/drug effects ; Pseudomonas aeruginosa/physiology ; Surface Properties ; Xenopus Proteins/chemistry ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Design, recombinant expression, and antibacterial activity of a novel hybrid magainin-thanatin antimicrobial peptide.
Autorzy :
Tian L; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Zhang D; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Su P; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Wei Y; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Wang Z; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Wang PX; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Dai CJ; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
Gong GL; a School of Food and Bioengineering , Shaanxi University of Science & Technology , Xi'an , China.
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Źródło :
Preparative biochemistry & biotechnology [Prep Biochem Biotechnol] 2019; Vol. 49 (5), pp. 427-434. Date of Electronic Publication: 2019 Mar 12.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Magainins/*pharmacology
Recombinant Fusion Proteins/*pharmacology
Antimicrobial Cationic Peptides/genetics ; Bacillus subtilis/drug effects ; Base Sequence ; Computational Biology ; Drug Design ; Escherichia coli/drug effects ; Escherichia coli/genetics ; Magainins/genetics ; Microbial Sensitivity Tests ; Plasmids/genetics ; Protein Engineering/methods ; Recombinant Fusion Proteins/genetics ; Staphylococcus aureus/drug effects
Czasopismo naukowe
Tytuł :
Efficacy of designer K11 antimicrobial peptide (a hybrid of melittin, cecropin A1 and magainin 2) against Acinetobacter baumannii-infected wounds.
Autorzy :
Rishi P; Department of Microbiology, Basic Medical Sciences Block I, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
Vashist T; Department of Microbiology, Basic Medical Sciences Block I, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
Sharma A; Department of Microbial Biotechnology, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
Kaur A; Department of Microbiology, Basic Medical Sciences Block I, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
Kaur A; Department of Microbiology, Basic Medical Sciences Block I, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
Kaur N; Department of Microbiology, Basic Medical Sciences Block I, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.; CSIR-Institute of Microbial Technology, Sector-39 A, Chandigarh-160036, India.
Kaur IP; University Institute of Pharmaceutical Sciences, Panjab University, Chandigarh-160014, India.
Tewari R; Department of Microbial Biotechnology, South Campus, Sector 25, Panjab University, Chandigarh-160014, India.
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Źródło :
Pathogens and disease [Pathog Dis] 2018 Oct 01; Vol. 76 (7). Date of Electronic Publication: 2018 Oct 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acinetobacter Infections/*drug therapy
Anti-Infective Agents/*administration & dosage
Antimicrobial Cationic Peptides/*administration & dosage
Magainins/*administration & dosage
Melitten/*administration & dosage
Recombinant Fusion Proteins/*administration & dosage
Wound Infection/*drug therapy
Xenopus Proteins/*administration & dosage
Acinetobacter Infections/microbiology ; Acinetobacter baumannii/drug effects ; Acinetobacter baumannii/ultrastructure ; Animals ; Anti-Infective Agents/pharmacology ; Antimicrobial Cationic Peptides/genetics ; Antimicrobial Cationic Peptides/pharmacology ; Disease Models, Animal ; Hydrogel, Polyethylene Glycol Dimethacrylate/administration & dosage ; Magainins/genetics ; Magainins/pharmacology ; Melitten/genetics ; Melitten/pharmacology ; Mice ; Microscopy, Confocal ; Microscopy, Electron ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/pharmacology ; Time Factors ; Treatment Outcome ; Wound Healing ; Wound Infection/microbiology ; Xenopus Proteins/genetics ; Xenopus Proteins/pharmacology
Czasopismo naukowe
Tytuł :
Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation.
Autorzy :
Jin S; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Brea RJ; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Rudd AK; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
Moon SP; Department of Chemistry, University of Southern California, Los Angeles, CA, 90089, USA.
Pratt MR; Department of Chemistry, University of Southern California, Los Angeles, CA, 90089, USA.
Devaraj NK; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA. .
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Źródło :
Nature communications [Nat Commun] 2020 Jun 03; Vol. 11 (1), pp. 2793. Date of Electronic Publication: 2020 Jun 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Micelles*
Lipids/*chemistry
Peptides/*chemistry
Surface-Active Agents/*chemistry
Amino Acid Sequence ; Kinetics ; Light ; Magainins/chemical synthesis ; Magainins/chemistry ; Peptides/chemical synthesis ; Ubiquitin/metabolism
Czasopismo naukowe
Tytuł :
Augmentation of endogenous GABA pool size induced by Magainin II peptide.
Autorzy :
Boostan N; Institute of Biochemistry and Biophysics, P. O. Box, 13145-1384, University of Tehran, Tehran, Iran.
Yazdanparast R; Institute of Biochemistry and Biophysics, P. O. Box, 13145-1384, University of Tehran, Tehran, Iran. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2018 Dec 02; Vol. 506 (4), pp. 891-894. Date of Electronic Publication: 2018 Nov 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Magainins/*pharmacology
gamma-Aminobutyric Acid/*metabolism
4-Aminobutyrate Transaminase/metabolism ; Animals ; Glutamate Decarboxylase/metabolism ; Magainins/metabolism ; Male ; Mice ; Succinate-Semialdehyde Dehydrogenase/metabolism
Czasopismo naukowe
Tytuł :
The "pre-assembled state" of magainin 2 lysine-linked dimer determines its enhanced antimicrobial activity.
Autorzy :
Lorenzón EN; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil. Electronic address: .
Nobre TM; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.
Caseli L; Institutode Ciências Ambientais, Químicas e Farmacêuticas, Universidade Federal de São Paulo, Diadema, SP, Brazil.
Cilli EM; Institutode Química, Universidade Estadual Paulista, Araraquara, SP, Brazil.
da Hora GCA; Departamentode Química Fundamental, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Soares TA; Departamentode Química Fundamental, Universidade Federal de Pernambuco, Recife, PE, Brazil.
Oliveira ON Jr; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil.
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Źródło :
Colloids and surfaces. B, Biointerfaces [Colloids Surf B Biointerfaces] 2018 Jul 01; Vol. 167, pp. 432-440. Date of Electronic Publication: 2018 Apr 20.
Typ publikacji :
Journal Article
MeSH Terms :
Protein Multimerization*
Anti-Infective Agents/*chemistry
Lysine/*chemistry
Magainins/*chemistry
Anti-Infective Agents/metabolism ; Anti-Infective Agents/pharmacology ; Cell Membrane/chemistry ; Cell Membrane/drug effects ; Cell Membrane/metabolism ; Escherichia coli/drug effects ; Lipid Bilayers/chemistry ; Lipid Bilayers/metabolism ; Lysine/metabolism ; Magainins/metabolism ; Magainins/pharmacology ; Molecular Dynamics Simulation ; Protein Binding ; Unilamellar Liposomes/chemistry ; Unilamellar Liposomes/metabolism
Czasopismo naukowe
Tytuł :
Assessing topology and surface orientation of an antimicrobial peptide magainin 2 using mechanically aligned bilayers and electron paramagnetic resonance spectroscopy.
Autorzy :
Mayo DJ; Department of Chemistry and Biochemistry, Miami University, Oxford, OH, 45056, United States.
Sahu ID; Department of Chemistry and Biochemistry, Miami University, Oxford, OH, 45056, United States.
Lorigan GA; Department of Chemistry and Biochemistry, Miami University, Oxford, OH, 45056, United States. Electronic address: .
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Źródło :
Chemistry and physics of lipids [Chem Phys Lipids] 2018 Jul; Vol. 213, pp. 124-130. Date of Electronic Publication: 2018 Apr 22.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Lipid Bilayers/*chemistry
Magainins/*chemistry
Amino Acid Sequence ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/metabolism ; Cyclic N-Oxides/chemistry ; Electron Spin Resonance Spectroscopy ; Lipid Bilayers/metabolism ; Magainins/chemical synthesis ; Magainins/metabolism ; Spin Labels
Czasopismo naukowe
Tytuł :
Synergy on Surfaces: Anti-Biofouling Interfaces Using Surface-Attached Antimicrobial Peptides PGLa and Magainin-2.
Autorzy :
Shtreimer Kandiyote N; Department of Desalination and Water Treatment, Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research , Ben-Gurion University of the Negev , Sede-Boqer Campus , Midreshet Ben Gurion 84990 , Israel.
Mohanraj G; Department of Desalination and Water Treatment, Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research , Ben-Gurion University of the Negev , Sede-Boqer Campus , Midreshet Ben Gurion 84990 , Israel.
Mao C; Department of Desalination and Water Treatment, Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research , Ben-Gurion University of the Negev , Sede-Boqer Campus , Midreshet Ben Gurion 84990 , Israel.
Kasher R; Department of Desalination and Water Treatment, Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research , Ben-Gurion University of the Negev , Sede-Boqer Campus , Midreshet Ben Gurion 84990 , Israel.
Arnusch CJ; Department of Desalination and Water Treatment, Zuckerberg Institute for Water Research, The Jacob Blaustein Institutes for Desert Research , Ben-Gurion University of the Negev , Sede-Boqer Campus , Midreshet Ben Gurion 84990 , Israel.
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Źródło :
Langmuir : the ACS journal of surfaces and colloids [Langmuir] 2018 Sep 18; Vol. 34 (37), pp. 11147-11155. Date of Electronic Publication: 2018 Sep 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*chemistry
Antimicrobial Cationic Peptides/*chemistry
Biofouling/*prevention & control
Magainins/*chemistry
Xenopus Proteins/*chemistry
Animals ; Anti-Bacterial Agents/chemical synthesis ; Biofilms/drug effects ; Magainins/chemical synthesis ; Membranes, Artificial ; Pseudomonas aeruginosa/drug effects ; Xenopus Proteins/chemical synthesis ; Xenopus laevis
Czasopismo naukowe
Tytuł :
Expression of a recombinant hybrid antimicrobial peptide magainin II-cecropin B in the mycelium of the medicinal fungus Cordyceps militaris and its validation in mice.
Autorzy :
Zhang M; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Shan Y; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Gao H; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Wang B; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Liu X; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Dong Y; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Liu X; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Yao N; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Zhou Y; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China.
Li X; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China. .
Li H; College of Life Sciences, Engineering Research Center of the Chinese Ministry of Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural University, Changchun, 130118, Jilin, China. .
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Źródło :
Microbial cell factories [Microb Cell Fact] 2018 Feb 05; Vol. 17 (1), pp. 18. Date of Electronic Publication: 2018 Feb 05.
Typ publikacji :
Journal Article
MeSH Terms :
Anti-Infective Agents/*pharmacology
Cecropins/*genetics
Cordyceps/*genetics
Escherichia coli/*drug effects
Magainins/*genetics
Mycelium/*genetics
Animal Feed ; Animals ; Anti-Bacterial Agents/adverse effects ; Anti-Infective Agents/metabolism ; Cecropins/metabolism ; Cecropins/pharmacology ; Cordyceps/chemistry ; Immunomodulation ; Intestines/drug effects ; Intestines/microbiology ; Magainins/metabolism ; Magainins/pharmacology ; Mice ; Mice, Inbred BALB C ; Mycelium/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/isolation & purification
Czasopismo naukowe
Tytuł :
Enhanced transdermal delivery with less irritation by magainin pore-forming peptide with a N-lauroylsarcosine and sorbitan monolaurate mixture.
Autorzy :
Lee H; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Park J; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea.
Kim YC; Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Republic of Korea. .
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Źródło :
Drug delivery and translational research [Drug Deliv Transl Res] 2018 Feb; Vol. 8 (1), pp. 54-63.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Hexoses/*administration & dosage
Irritants/*administration & dosage
Magainins/*administration & dosage
Sarcosine/*analogs & derivatives
Administration, Cutaneous ; Animals ; Cell Survival/drug effects ; Hexoses/chemistry ; Hexoses/toxicity ; Irritants/chemistry ; Irritants/toxicity ; Magainins/chemistry ; Magainins/toxicity ; Mice ; NIH 3T3 Cells ; Sarcosine/administration & dosage ; Sarcosine/chemistry ; Sarcosine/toxicity ; Skin/drug effects ; Swine
Czasopismo naukowe
Tytuł :
Synergism of Antimicrobial Frog Peptides Couples to Membrane Intrinsic Curvature Strain.
Autorzy :
Leber R; Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.
Pachler M; Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.
Kabelka I; Central European Institute of Technology, Brno, Czech Republic; Faculty of Science, Masaryk University, Brno, Czech Republic.
Svoboda I; Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.
Enkoller D; Fresenius Kabi Austria GmbH, Graz, Austria.
Vácha R; Central European Institute of Technology, Brno, Czech Republic; Faculty of Science, Masaryk University, Brno, Czech Republic.
Lohner K; Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Graz, Austria; BioTechMed Graz, Graz, Austria.
Pabst G; Institute of Molecular Biosciences, Biophysics Division, University of Graz, NAWI Graz, Graz, Austria; BioTechMed Graz, Graz, Austria. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2018 Apr 24; Vol. 114 (8), pp. 1945-1954.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Stress, Mechanical*
Anti-Bacterial Agents/*pharmacology
Cell Membrane/*metabolism
Magainins/*pharmacology
Amino Acid Sequence ; Anti-Bacterial Agents/chemistry ; Biomechanical Phenomena/drug effects ; Cell Membrane/drug effects ; Drug Synergism ; Escherichia coli/cytology ; Escherichia coli/drug effects ; Magainins/chemistry ; Protein Multimerization ; Thermodynamics
Czasopismo naukowe
Tytuł :
Molecular mechanism of synergy between the antimicrobial peptides PGLa and magainin 2.
Autorzy :
Zerweck J; Karlsruhe Institute of Technology (KIT), Institute of Organic Chemistry, Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
Strandberg E; KIT, Institute of Biological Interfaces (IBG-2), POB 3640, 76021, Karlsruhe, Germany.
Kukharenko O; Karlsruhe Institute of Technology (KIT), Institute of Organic Chemistry, Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany.
Reichert J; KIT, Institute of Biological Interfaces (IBG-2), POB 3640, 76021, Karlsruhe, Germany.
Bürck J; KIT, Institute of Biological Interfaces (IBG-2), POB 3640, 76021, Karlsruhe, Germany.
Wadhwani P; KIT, Institute of Biological Interfaces (IBG-2), POB 3640, 76021, Karlsruhe, Germany.
Ulrich AS; Karlsruhe Institute of Technology (KIT), Institute of Organic Chemistry, Fritz-Haber-Weg 6, 76131, Karlsruhe, Germany. .; KIT, Institute of Biological Interfaces (IBG-2), POB 3640, 76021, Karlsruhe, Germany. .
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Źródło :
Scientific reports [Sci Rep] 2017 Oct 13; Vol. 7 (1), pp. 13153. Date of Electronic Publication: 2017 Oct 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Infective Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Magainins/*pharmacology
Anti-Infective Agents/chemistry ; Antimicrobial Cationic Peptides/chemistry ; Circular Dichroism ; Drug Synergism ; Escherichia coli/drug effects ; Magainins/chemistry ; Microbial Sensitivity Tests ; Staphylococcus aureus/drug effects
Czasopismo naukowe
Tytuł :
Studying the Interaction of Magainin 2 and Cecropin A with E. coli Bacterial Cells Using Circular Dichroism.
Autorzy :
Avitabile C; Institute of Biostructure and Bioimaging CNR, via Mezzocannnone 16, 80134, Naples, Italy.
D'Andrea LD; Institute of Biostructure and Bioimaging CNR, via Mezzocannnone 16, 80134, Naples, Italy.
Romanelli A; Institute of Biostructure and Bioimaging CNR, via Mezzocannnone 16, 80134, Naples, Italy. .; Department of Pharmacy, University of Naples 'Federico II', via Mezzocannone 16, Naples, 80134, Italy. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2017; Vol. 1548, pp. 247-253.
Typ publikacji :
Journal Article
MeSH Terms :
Circular Dichroism*/methods
Escherichia coli*/drug effects
Escherichia coli*/metabolism
Antimicrobial Cationic Peptides/*chemistry
Magainins/*chemistry
Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antimicrobial Cationic Peptides/metabolism ; Antimicrobial Cationic Peptides/pharmacology ; Magainins/metabolism ; Magainins/pharmacology ; Protein Binding ; Protein Structure, Secondary
Czasopismo naukowe
Tytuł :
H-NMR and MD Simulations Reveal Membrane-Bound Conformation of Magainin 2 and Its Synergy with PGLa.
Autorzy :
Strandberg E; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology, Karlsruhe, Germany.
Horn D; Institute of Organic Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Reißer S; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology, Karlsruhe, Germany; Institute of Physical Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Zerweck J; Institute of Organic Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany.
Wadhwani P; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology, Karlsruhe, Germany.
Ulrich AS; Institute of Biological Interfaces (IBG-2), Karlsruhe Institute of Technology, Karlsruhe, Germany; Institute of Organic Chemistry, Karlsruhe Institute of Technology, Karlsruhe, Germany. Electronic address: .
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Źródło :
Biophysical journal [Biophys J] 2016 Nov 15; Vol. 111 (10), pp. 2149-2161.
Typ publikacji :
Journal Article
MeSH Terms :
Molecular Dynamics Simulation*
Antimicrobial Cationic Peptides/*pharmacology
Cell Membrane/*metabolism
Magainins/*chemistry
Magainins/*metabolism
Drug Synergism ; Magainins/pharmacology ; Magnetic Resonance Spectroscopy ; Protein Conformation, alpha-Helical
Czasopismo naukowe
Tytuł :
Development of Amphipathic Antimicrobial Peptide Foldamers Based on Magainin 2 Sequence.
Autorzy :
Goto C; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.; Graduate School of Medical Health Sciences, Yokohama City University, Yokohama-shi, Kanagawa, 230-0045, Japan.
Hirano M; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Hayashi K; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Kikuchi Y; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.; Department of Nutrition, Chiba Prefectural University of Health Sciences University, 2-10-1 Wakaba, Mihama-ku, Chiba, 261-0014, Japan.
Hara-Kudo Y; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Misawa T; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.
Demizu Y; National Institute of Health Sciences, 3-25-26, Tonomachi, Kawasaki-ku, Kawasaki-shi, Kanagawa, 210-9501, Japan.; Graduate School of Medical Health Sciences, Yokohama City University, Yokohama-shi, Kanagawa, 230-0045, Japan.
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Źródło :
ChemMedChem [ChemMedChem] 2019 Nov 20; Vol. 14 (22), pp. 1911-1916. Date of Electronic Publication: 2019 Nov 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Development*
Anti-Bacterial Agents/*pharmacology
Antimicrobial Cationic Peptides/*pharmacology
Gram-Negative Bacteria/*drug effects
Gram-Positive Bacteria/*drug effects
Magainins/*chemistry
Xenopus Proteins/*chemistry
Amino Acid Sequence ; Anti-Bacterial Agents/chemical synthesis ; Anti-Bacterial Agents/chemistry ; Antimicrobial Cationic Peptides/chemical synthesis ; Antimicrobial Cationic Peptides/chemistry ; Hydrophobic and Hydrophilic Interactions ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship
Czasopismo naukowe

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