Autor: "Mahmoud, M." - OpacWWW

Skocz do pozycji: 1.

Tytuł:: New benzothiazole hybrids as potential VEGFR-2 inhibitors: design, synthesis, anticancer evaluation, and in silico study.
Autorzy:: Al-Sanea MM; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Hamdi A; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Mohamed AAB; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
El-Shafey HW; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Moustafa M; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.
Elgazar AA; Department of Pharmacognosy, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Ur Rahman H; Department of Clinical Pharmacy, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Parambi DGT; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Elbargisy RM; Department of Pharmaceutics, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Selim S; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.
Bukhari SNA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
Magdy Hendawy O; Department of Pharmacology, College of Pharmacy, Jouf University, Aljouf, Saudi Arabia.
Tawfik SS; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2023 Dec; Vol. 38 (1), pp. 2166036.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Humans ; Benzothiazoles/pharmacology ; Cell Proliferation ; Drug Screening Assays, Antitumor ; MCF-7 Cells ; Molecular Docking Simulation ; Molecular Structure ; Protein Kinase Inhibitors/pharmacology ; Sorafenib/pharmacology ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 2.

Tytuł:: New 1,2,3-Triazole/1,2,4-triazole Hybrids as Aromatase Inhibitors: Design, Synthesis, and Apoptotic Antiproliferative Activity.
Autorzy:: Maghraby MT; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, New Valley University, New Valley 72511, Egypt.
Mazyad Almutairi T; Department of Chemistry, College of Science, King Saud University, Riyadh 11451, Saudi Arabia.
Bräse S; Institute of Biological and Chemical Systems, IBCS-FMS, Karlsruhe Institute of Technology, 76131 Karlsruhe, Germany.
Salem OIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Youssif BGM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.
Sheha MM; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut 71526, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, New-Assiut 71684, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Oct 14; Vol. 28 (20). Date of Electronic Publication: 2023 Oct 14.
Typ publikacji:: Journal Article
MeSH Terms:: Aromatase Inhibitors*/chemistry
Antineoplastic Agents*/chemistry
Aromatase ; Molecular Docking Simulation ; Structure-Activity Relationship ; Erlotinib Hydrochloride/pharmacology ; Cell Line, Tumor ; Triazoles/chemistry ; Cell Proliferation ; Drug Screening Assays, Antitumor ; Molecular Structure

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: Antimicrobial, Antibiofilm, and Anticancer Activities of Syzygium aromaticum Essential Oil Nanoemulsion.
Autorzy:: Shehabeldine AM; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.
Doghish AS; Department of Biochemistry, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Egypt.; Biochemistry and Molecular Biology Department, Faculty of Pharmacy (Boys), Al-Azhar University, Nasr City 11231, Egypt.
El-Dakroury WA; Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Badr University in Cairo (BUC), Badr City 11829, Egypt.
Hassanin MMH; Ornamental, Medicinal and Aromatic Plant Disease Department, Plant Pathology Research Institute, Agricultural Research Center (ARC), Giza 12619, Egypt.
Al-Askar AA; Department of Botany and Microbiology, Faculty of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.
AbdElgawad H; Integrated Molecular Plant Physiology Research (IMPRES), Department of Biology, University of Antwerp, 2022 Antwerp, Belgium.
Hashem AH; Botany and Microbiology Department, Faculty of Science, Al-Azhar University, Nasr City 11884, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2023 Aug 01; Vol. 28 (15). Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:: Journal Article
MeSH Terms:: Biofilms*/drug effects
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Oils, Volatile*/chemistry
Oils, Volatile*/pharmacology
Syzygium*/chemistry
Anti-Bacterial Agents*/chemistry
Anti-Bacterial Agents*/pharmacology
Antifungal Agents*/chemistry
Antifungal Agents*/pharmacology
Emulsions ; Dynamic Light Scattering ; Microscopy, Electron, Transmission ; Hep G2 Cells ; MCF-7 Cells ; Humans ; Apoptosis ; Nanoparticle Drug Delivery System ; Nanostructures/chemistry ; Staphylococcus aureus/drug effects ; Fungi/drug effects

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 4.

Tytuł:: Design, synthesis, and modelling study of new 1,2,3-triazole/chalcone hybrids with antiproliferative action as epidermal growth factor receptor inhibitors.
Autorzy:: Maghraby MT; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.; Pharmaceutical Chemistry Department, Faculty of Pharmacy, New Valley University, Egypt.
Salem OIA; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Youssif BGM; Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Sheha MM; Department of Medicinal Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Sphinx University, Assiut, Egypt.; Pokaż więcej
Źródło:: Chemical biology & drug design [Chem Biol Drug Des] 2023 Mar; Vol. 101 (3), pp. 749-759. Date of Electronic Publication: 2022 Dec 12.
Typ publikacji:: Journal Article
MeSH Terms:: Chalcones*/pharmacology
Chalcone*/pharmacology
Antineoplastic Agents*/pharmacology
Triazoles/pharmacology ; Structure-Activity Relationship ; Cell Proliferation ; Cell Line, Tumor ; Molecular Docking Simulation ; Proto-Oncogene Proteins B-raf/metabolism ; Drug Screening Assays, Antitumor ; ErbB Receptors/metabolism ; Doxorubicin/pharmacology ; Molecular Structure ; Protein Kinase Inhibitors/pharmacology

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 5.

Tytuł:: The new potential application for Mg(II) cysteinedithiocarbamate complex with anticancer activity.
Autorzy:: Raya I; Department of Chemistry, Faculty of Mathematics, and Natural Science, Hasanuddin University, Makassar, Indonesia.
Kartina D; Eijkman Research Center for Molecular Biology, Health Research Organization, BRIN, Jakarta, Indonesia.; Department of Chemistry, Faculty of Mathematics, and Natural Science, Universitas Pakuan Bogor, Jawa Barat, Indonesia.
Irfandi R; Department of Biology Education, Faculty of Teacher Training and Education, Universitas Puangrimaggalatung, Sengkang, Indonesia.
Sufiandi S; Directorate of Laboratory Management, Research Facilities, and Science and Technology Park, Deputy for Research and Innovation Infrastructure - The National Research and Innovation Agency of The Republic of Indonesia, Jakarta, Indonesia.
Wijaya RI; Department of Chemistry, Faculty of Mathematics, and Natural Science, Universitas Pakuan Bogor, Jawa Barat, Indonesia.
Prihantono P; Department of Surgery, Faculty of Medical, Hasanuddin University, Makassar, Indonesia.
Abdalrazaq EA; Department of Chemistry, Faculty of Science, Al Hussein Bin Talal University, Ma'an, Jordan.
Kandeel M; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa, Saudi Arabia.
Usman AN; Midwifery Study Program, Hasanuddin University, Makassar, Indonesia.; Pokaż więcej
Źródło:: Breast disease [Breast Dis] 2023; Vol. 42 (1), pp. 177-182.
Typ publikacji:: Journal Article
MeSH Terms:: Breast Neoplasms*
Antineoplastic Agents*/pharmacology
Humans ; Female ; Ligands

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.
Autorzy:: Abdelsalam EA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Abd El-Hafeez AA; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Pharmacology and Experimental Oncology Unit, Department of Cancer Biology, National Cancer Institute, Cairo University, Cairo, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.; School of Biotechnology, Badr University in Cairo, Badr City, Cairo, Egypt.
El Hassab MA; Department of Medicinal Chemistry, Faculty of Pharmacy, King Salman International University (KSIU), South Sinai, Egypt.
Marzouk HMM; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Biochemistry, Faculty of Medicine, Minia University, El-Minia, Egypt.
Elaasser MM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
Abou Taleb NA; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.
Amin KM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University, Cairo, Egypt.
Abdel-Aziz HA; Department of Applied Organic Chemistry, National Research Centre, Dokki, Giza, Egypt.
Ghosh P; Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA.; Moores Comprehensive Cancer Center, University of California San Diego, La Jolla, CA, USA.; Veterans Affairs Medical Center, La Jolla, CA, USA.
Hammad SF; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Helwan University, Cairo, Egypt.; PharmD Program and Basic and Applied Sciences Institute, Egypt-Japan University of Science and Technology (E-JUST), Alexandria, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2022 Dec; Vol. 37 (1), pp. 2265-2282.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Lung Neoplasms*/drug therapy
Lung Neoplasms*/pathology
Pyrazoles/*pharmacology
Cell Line, Tumor ; Cell Proliferation ; Drug Screening Assays, Antitumor ; ErbB Receptors/metabolism ; Humans ; Molecular Docking Simulation ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Pyrazoles/chemistry ; Structure-Activity Relationship ; Vascular Endothelial Growth Factor Receptor-2

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 7.

Tytuł:: Carnosine Potentiates Doxorubicin-Induced Cytotoxicity in Resistant NCI/ADR-RES Cells by Inhibiting P-Glycoprotein-In Silico and In Vitro Evidence.
Autorzy:: Morsy MA; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt.
Kandeel M; Department of Biomedical Sciences, College of Veterinary Medicine, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Department of Pharmacology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafr El-Sheikh 33516, Egypt.
Ibrahim ARN; Clinical Pharmacy Department, College of Pharmacy, King Khalid University, Abha 61441, Saudi Arabia.; Department of Biochemistry, Faculty of Pharmacy, Minia University, El-Minia 61511, Egypt.
Abdel-Gaber SA; Department of Pharmacology, Faculty of Medicine, Minia University, El-Minia 61511, Egypt.
Jacob S; Department of Pharmaceutical Sciences, College of Pharmacy, Gulf Medical University, Ajman 4184, United Arab Emirates.
Venugopala KN; Department of Pharmaceutical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.; Department of Biotechnology and Food Science, Faculty of Applied Sciences, Durban University of Technology, Durban 4000, South Africa.
Shinu P; Department of Biomedical Sciences, College of Clinical Pharmacy, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
El-Daly M; Department of Pharmacology & Toxicology, Faculty of Pharmacy, Minia University, El-Minia 61511, Egypt.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Oct 30; Vol. 27 (21). Date of Electronic Publication: 2022 Oct 30.
Typ publikacji:: Journal Article
MeSH Terms:: Carnosine*/pharmacology
Carnosine*/metabolism
Antineoplastic Agents*/pharmacology
Drug Resistance, Multiple ; ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism ; Molecular Docking Simulation ; Drug Resistance, Neoplasm ; Doxorubicin/pharmacology ; Rhodamine 123/pharmacology ; Verapamil/pharmacology ; ATP Binding Cassette Transporter, Subfamily B/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 8.

Tytuł:: A Novel Docetaxel-Biotin Chemical Conjugate for Prostate Cancer Treatment.
Autorzy:: Rayan M; Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka EL-Garbiah 30100, Israel.
Shadafny S; R&D Department, IDD Therapeutics LTD, Nazareth 1711102, Israel.; Chemistry Education Branch, Iksal Comprehensive School, Iksal 16920, Israel.
Falah A; Science Department, York University, Toronto, ON M3J 1P3, Canada.
Falah M; Institute for Medical Research, Holy Family Hospital, Nazareth 16000, Israel.
Abu-Lafi S; Faculty of Pharmacy, Al-Quds University, Abu-Dies 144, Palestine.
Asli S; The Institute of Applied Research, Galilee Society, Shefa-Amr 2020, Israel.; Faculty of Science, Al-Qasemi Academic College, Baka EL-Garbiah 30100, Israel.
Rayan A; Drug Discovery Informatics Lab, QRC-Qasemi Research Center, Al-Qasemi Academic College, Baka EL-Garbiah 30100, Israel.; R&D Department, IDD Therapeutics LTD, Nazareth 1711102, Israel.; Faculty of Science, Al-Qasemi Academic College, Baka EL-Garbiah 30100, Israel.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2022 Jan 31; Vol. 27 (3). Date of Electronic Publication: 2022 Jan 31.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*pharmacology
Biotin/*chemistry
Docetaxel/*pharmacology
Prostatic Neoplasms/*drug therapy
Animals ; Antineoplastic Agents/chemistry ; Apoptosis ; Cell Proliferation ; Docetaxel/chemistry ; Female ; Humans ; Male ; Mice ; Mice, Inbred BALB C ; Mice, Nude ; Prostatic Neoplasms/metabolism ; Prostatic Neoplasms/pathology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 9.

Tytuł:: Mitochondrial Pro-Apoptotic Properties of Sinularia compressa from Persian Gulf against Breast Cancer Cells and Its Chemical Composition.
Autorzy:: Pour PM; Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.
Yegdaneh A; Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.
Aghaei M; Department of Clinical Biochemistry, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.
Kazemi F; Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.
Ghanadian M; Department of Pharmacognosy, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.; Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, I.R, Iran.; Pokaż więcej
Źródło:: Nutrition and cancer [Nutr Cancer] 2022; Vol. 74 (6), pp. 2276-2290. Date of Electronic Publication: 2021 Nov 26.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Anthozoa*/metabolism
Antineoplastic Agents*/pharmacology
Breast Neoplasms*/drug therapy
Animals ; Apoptosis ; Caspase 9/genetics ; Caspase 9/metabolism ; Cell Line, Tumor ; Female ; Humans ; Indian Ocean ; MCF-7 Cells ; Membrane Potential, Mitochondrial ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 10.

Tytuł:: Naturally Occurring Chromone Glycosides: Sources, Bioactivities, and Spectroscopic Features.
Autorzy:: Amen Y; Department of Agro-Environmental Sciences, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Elsbaey M; Department of Pharmacognosy, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt.
Othman A; Department of Agro-Environmental Sciences, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo 11371, Egypt.
Sallam M; Department of Pharmacognosy, Faculty of Pharmacy, Al-Azhar University, Cairo 11371, Egypt.
Shimizu K; Department of Agro-Environmental Sciences, Graduate School of Bioresources and Bioenvironmental Sciences, Kyushu University, Fukuoka 819-0395, Japan.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Dec 16; Vol. 26 (24). Date of Electronic Publication: 2021 Dec 16.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Anti-Infective Agents*/chemistry
Anti-Infective Agents*/metabolism
Anti-Infective Agents*/therapeutic use
Anti-Inflammatory Agents*/chemistry
Anti-Inflammatory Agents*/metabolism
Anti-Inflammatory Agents*/therapeutic use
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/metabolism
Antineoplastic Agents*/therapeutic use
Chromones*/chemistry
Chromones*/metabolism
Chromones*/therapeutic use
Glycosides*/biosynthesis
Glycosides*/chemistry
Glycosides*/therapeutic use
Animals ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Structure

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 11.

Tytuł:: Dual-ligated metal organic framework as novel multifunctional nanovehicle for targeted drug delivery for hepatic cancer treatment.
Autorzy:: Fytory M; Nanomedicine Labs, Center for Materials Science (CMS), Zewail City of Science and Technology, Giza, 12578, Egypt.; Material Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, 62511, Egypt.
Arafa KK; Nanomedicine Labs, Center for Materials Science (CMS), Zewail City of Science and Technology, Giza, 12578, Egypt.
El Rouby WMA; Material Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, 62511, Egypt.
Farghali AA; Material Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences (PSAS), Beni-Suef University, Beni-Suef, 62511, Egypt.
Abdel-Hafiez M; Department of Physics and Astronomy, Uppsala University, Box 516, 75120, Uppsala, Sweden.; Department of Physics, Faculty of Science, Fayoum University, Fayoum, 63514, Egypt.
El-Sherbiny IM; Nanomedicine Labs, Center for Materials Science (CMS), Zewail City of Science and Technology, Giza, 12578, Egypt. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Oct 06; Vol. 11 (1), pp. 19808. Date of Electronic Publication: 2021 Oct 06.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Antineoplastic Agents/*administration & dosage
Carcinoma, Hepatocellular/*drug therapy
Doxorubicin/*administration & dosage
Drug Carriers/*pharmacology
Liver Neoplasms/*drug therapy
Metal-Organic Frameworks/*pharmacology
Fibroblasts ; Hep G2 Cells ; Humans

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 12.

Tytuł:: Design, Synthesis, Molecular Modeling and Antitumor Evaluation of Novel Indolyl-Pyrimidine Derivatives with EGFR Inhibitory Activity.
Autorzy:: Ahmed NM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo 11795, Egypt.
Youns MM; Biochemistry Department, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo 11795, Egypt.; Oman College of Health Sciences, Muscat 123, Oman.
Soltan MK; Oman College of Health Sciences, Muscat 123, Oman.; Medicinal Chemistry Department, Faculty of Pharmacy, Zagazig University, Zagazig 44519, Egypt.
Said AM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Helwan University, Ein-Helwan, Helwan, Cairo 11795, Egypt.; Department of Chemistry, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 25; Vol. 26 (7). Date of Electronic Publication: 2021 Mar 25.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemical synthesis
Antineoplastic Agents*/chemistry
Antineoplastic Agents*/pharmacology
Models, Molecular*
Neoplasm Proteins*/antagonists & inhibitors
Neoplasm Proteins*/metabolism
Pyrimidines*/chemical synthesis
Pyrimidines*/chemistry
Pyrimidines*/pharmacology
Neoplasms/*drug therapy
Animals ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/metabolism ; HCT116 Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Mice ; Neoplasms/metabolism ; Neoplasms/pathology ; Xenograft Model Antitumor Assays

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 13.

Tytuł:: Molecular docking, pharmacokinetic studies, and in vivo pharmacological study of indole derivative 2-(5-methoxy-2-methyl-1H-indole-3-yl)-N'-[(E)-(3-nitrophenyl) methylidene] acetohydrazide as a promising chemoprotective agent against cisplatin induced organ damage.
Autorzy:: Razak S; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia. .
Afsar T; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Bibi N; Department of Bioinformatics, Shaheed Benazir Bhutto Women University, Khyber Pakhtunkhwa, Peshawar, Pakistan.
Abulmeaty M; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Qamar W; Department of Pharmocology and Toxicology, Central Laboratory, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.
Almajwal A; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Inam A; Department of Bioinformatics, Shaheed Benazir Bhutto Women University, Khyber Pakhtunkhwa, Peshawar, Pakistan.
Al Disi D; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Shabbir M; Atta-Ur-Rahman School of Applied Biosciences, National University of Sciences and Technology, Islamabad, Pakistan.
Bhat MA; Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh, 11451, Kingdom of Saudi Arabia.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Mar 18; Vol. 11 (1), pp. 6245. Date of Electronic Publication: 2021 Mar 18.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Molecular Docking Simulation*
Antineoplastic Agents/*adverse effects
Antioxidants/*administration & dosage
Antioxidants/*pharmacokinetics
Cisplatin/*adverse effects
Indoles/*administration & dosage
Indoles/*pharmacokinetics
Animals ; Antineoplastic Agents/administration & dosage ; Antioxidants/chemistry ; Cisplatin/administration & dosage ; Glutathione Peroxidase/metabolism ; Indoles/chemistry ; Inflammation/chemically induced ; Inflammation/drug therapy ; Inflammation/metabolism ; Male ; Malondialdehyde/metabolism ; Models, Animal ; Nitric Oxide/metabolism ; Oxidative Stress/drug effects ; Rats ; Rats, Wistar ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Superoxide Dismutase/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 14.

Tytuł:: Microwave-Assisted Rapid Green Synthesis of Gold Nanoparticles Using Seed Extract of Trachyspermum ammi : ROS Mediated Biofilm Inhibition and Anticancer Activity.
Autorzy:: Perveen K; Department of Botany and Microbiology, College of Science, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Husain FM; Department of Food Science and Nutrition, College of Food and Agriculture Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Qais FA; Department of Ag. Microbiology, Aligarh Muslim University, Aligarh 202002, India.
Khan A; Central Laboratory, Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Razak S; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Afsar T; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Alam P; Department of Biology, College of Science and Humanities, Prince Sattam bin Abdulaziz University, Alkharj 11942, Saudi Arabia.
Almajwal AM; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia.
Abulmeaty MMA; Department of Community Health Sciences, College of Applied Medical Sciences, King Saud University, 2460, Riyadh 11451, Saudi Arabia.; Pokaż więcej
Źródło:: Biomolecules [Biomolecules] 2021 Jan 30; Vol. 11 (2). Date of Electronic Publication: 2021 Jan 30.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Reactive Oxygen Species*
Antineoplastic Agents/*pharmacology
Apiaceae/*metabolism
Gold/*chemistry
Metal Nanoparticles/*chemistry
Seeds/*metabolism
Anisotropy ; Anti-Bacterial Agents/pharmacology ; Biofilms/drug effects ; Cell Survival ; Glutathione Transferase/metabolism ; Green Chemistry Technology ; Hep G2 Cells ; Humans ; Light ; Lipid Peroxidation ; Listeria monocytogenes/drug effects ; Microbial Sensitivity Tests ; Microscopy, Electron, Transmission ; Microwaves ; Plant Extracts/pharmacology ; Polysaccharides, Bacterial/chemistry ; Scattering, Radiation ; Serratia marcescens/drug effects ; Tetrazolium Salts/chemistry ; Thiazoles/chemistry ; X-Ray Diffraction

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 15.

Tytuł:: Data-Driven Discovery of Molecular Targets for Antibody-Drug Conjugates in Cancer Treatment.
Autorzy:: Razzaghdoust A; Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Rahmatizadeh S; Department of Health Information Technology and Management, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Mofid B; Department of Oncology, Shohada-e-Tajrish Medical Center, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Muhammadnejad S; Gene Therapy Research Center, Digestive Diseases Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
Parvin M; Department of Pathology, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Torbati PM; Department of Pathology, Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Basiri A; Urology and Nephrology Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.; Pokaż więcej
Źródło:: BioMed research international [Biomed Res Int] 2021 Jan 02; Vol. 2021, pp. 2670573. Date of Electronic Publication: 2021 Jan 02 (Print Publication: 2021).
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents*/chemistry
Antineoplastic Agents*/metabolism
Immunoconjugates*/chemistry
Immunoconjugates*/metabolism
Neoplasms*/drug therapy
Neoplasms*/genetics
Neoplasms*/metabolism
Drug Discovery/*methods
Proteomics/*methods
Data Mining ; Databases, Genetic ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 16.

Tytuł:: Discovery of 3,6-disubstituted pyridazines as a novel class of anticancer agents targeting cyclin-dependent kinase 2: synthesis, biological evaluation and in silico insights.
Autorzy:: Sabt A; Chemistry of Natural Compounds Department, National Research Centre, Dokki, Egypt.
Eldehna WM; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kafrelsheikh University, Kafrelsheikh, Egypt.
Al-Warhi T; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Alotaibi OJ; Department of Chemistry, College of Science, Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia.
Elaasser MM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo, Egypt.
Suliman H; Department of Medical Biochemistry, Faculty of Medicine, Alexandria University, Alexandria, Egypt.
Abdel-Aziz HA; Department of Applied Organic Chemistry, National Research Center, Giza, Egypt.; Pokaż więcej
Źródło:: Journal of enzyme inhibition and medicinal chemistry [J Enzyme Inhib Med Chem] 2020 Dec; Vol. 35 (1), pp. 1616-1630.
Typ publikacji:: Journal Article
MeSH Terms:: Drug Discovery*
Molecular Docking Simulation*
Antineoplastic Agents/*pharmacology
Cyclin-Dependent Kinase 2/*antagonists & inhibitors
Protein Kinase Inhibitors/*pharmacology
Pyridazines/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cyclin-Dependent Kinase 2/metabolism ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Protein Kinase Inhibitors/chemical synthesis ; Protein Kinase Inhibitors/chemistry ; Pyridazines/chemical synthesis ; Pyridazines/chemistry ; Structure-Activity Relationship

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 17.

Tytuł:: Synthesis of Novel Chalcone-Based Phenothiazine Derivatives as Antioxidant and Anticancer Agents.
Autorzy:: Al Zahrani NA; Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Chemistry Department, Faculty of Science, University of Jeddah, Jeddah 21959, Saudi Arabia.
El-Shishtawy RM; Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Dyeing, Printing and Textile Auxiliaries Department, Textile Research Division, National Research Centre, Dokki, Cairo 12611, Egypt.
Elaasser MM; The Regional Center for Mycology and Biotechnology, Al-Azhar University, Cairo 11759, Egypt.
Asiri AM; Chemistry Department, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Center of Excellence for Advanced Materials Research, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Oct 06; Vol. 25 (19). Date of Electronic Publication: 2020 Oct 06.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*chemistry
Antioxidants/*chemistry
Chalcones/*chemistry
Phenothiazines/*chemistry
Antineoplastic Agents/pharmacology ; Antioxidants/pharmacology ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Hep G2 Cells ; Humans ; MCF-7 Cells

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids.
Autorzy:: Batiha GE; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Alqahtani A; Department of Pharmacology, College of Pharmacy, King Khalid University, Guraiger, Abha 62529, Saudi Arabia.
Ojo OA; Department of Biochemistry, Landmark University, Omu-Aran 251101, Nigeria.
Shaheen HM; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Wasef L; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Elzeiny M; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Ismail M; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Shalaby M; Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour 22511, AlBeheira, Egypt.
Murata T; Department of Pharmacognosy, Tohoku Medical and Pharmaceutical University, Aoba-ku, Sendai 981-8558, Japan.
Zaragoza-Bastida A; Área Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo, Hidalgo 43600, Mexico.
Rivero-Perez N; Área Académica de Medicina Veterinaria y Zootecnia, Instituto de Ciencias Agropecuarias, Universidad Autónoma del Estado de Hidalgo, Rancho Universitario Av. Universidad km 1, EX-Hda de Aquetzalpa, Tulancingo, Hidalgo 43600, Mexico.
Magdy Beshbishy A; National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-13, Inada-cho, Obihiro 080-8555, Hokkaido, Japan.
Kasozi KI; Infection Medicine, Deanery of Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK.
Jeandet P; Research Unit 'Induced Resistance and Plant Bioprotection', EA 4707, SFR Condorcet FR CNRS 3417, Faculty of Sciences, University of Reims, PO Box 1039, CEDEX 2, 51687 Reims, France.
Hetta HF; Department of Medical Microbiology and Immunology, Faculty of Medicine, Assiut University, Assiut 71515, Egypt.; Department of Internal Medicine, University of Cincinnati College of Medicine, Clifton Ave, Cincinnati, OH 45221, USA.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2020 Jul 22; Vol. 21 (15). Date of Electronic Publication: 2020 Jul 22.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Anti-Infective Agents/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Antineoplastic Agents/*pharmacology
Antioxidants/*pharmacology
Capsicum/*chemistry
Capsicum/*classification
Fruit/*chemistry
Plant Extracts/*pharmacology
Capsicum/metabolism ; Carotenoids/analysis ; Flavonoids/analysis ; Irritants/pharmacology ; Phenols/analysis ; Plant Extracts/chemistry ; Vitamins/analysis

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: In vivo and in vitro biocompatibility study of MnFe 2 O 4 and Cr 2 Fe 6 O 12 as photosensitizer for photodynamic therapy and drug delivery of anti-cancer drugs.
Autorzy:: Aghajanzadeh M; Department of Pharmaceutical Biomaterials, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Naderi E; Department of Physics, Faculty of Science, Malayer University, Malayer, Iran.
Zamani M; Department of Pharmaceutical Biomaterials, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Sharafi A; Department of Pharmaceutical Biotechnology, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
Naseri M; Department of Physics, Faculty of Science, Malayer University, Malayer, Iran.
Danafar H; Biotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.; Zanjan Pharmaceutical Nanotechnology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran.; Pokaż więcej
Źródło:: Drug development and industrial pharmacy [Drug Dev Ind Pharm] 2020 May; Vol. 46 (5), pp. 846-851. Date of Electronic Publication: 2020 Apr 29.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*administration & dosage
Chromium/*administration & dosage
Drug Delivery Systems/*methods
Ferric Compounds/*administration & dosage
Manganese Compounds/*administration & dosage
Photochemotherapy/*methods
Photosensitizing Agents/*administration & dosage
Animals ; Antineoplastic Agents/metabolism ; Biocompatible Materials/administration & dosage ; Biocompatible Materials/metabolism ; Cell Survival/drug effects ; Cell Survival/physiology ; Chromium/metabolism ; Dose-Response Relationship, Drug ; Female ; Ferric Compounds/metabolism ; HEK293 Cells ; Humans ; MCF-7 Cells ; Male ; Manganese Compounds/metabolism ; Mice ; Photosensitizing Agents/metabolism

Czasopismo naukowe

na półce

Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Conjugation of Aspergillus flavipes Taxol with Porphyrin Increases the Anticancer Activity of Taxol and Ameliorates Its Cytotoxic Effects.
Autorzy:: El-Sayed ASA; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Fathalla M; Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Yassin MA; Enzymology and Fungal Biotechnology Lab, Botany and Microbiology Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Zein N; Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Morsy S; Chemistry Department, Faculty of Science, Zagazig University, Zagazig 44519, Egypt.
Sitohy M; Biochemistry Department, Faculty of Agriculture, Zagazig University, Zagazig 44519, Egypt.
Sitohy B; Department of Clinical Microbiology, Infection and Immunology, Umeå University, SE-90185 Umeå, Sweden.; Department of Radiation Sciences, Oncology, Umeå University, SE-90185 Umeå, Sweden.; Pokaż więcej
Źródło:: Molecules (Basel, Switzerland) [Molecules] 2020 Jan 09; Vol. 25 (2). Date of Electronic Publication: 2020 Jan 09.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Agents/*chemistry
Cell Proliferation/*drug effects
Paclitaxel/*chemistry
Porphyrins/*chemistry
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Aspergillus/chemistry ; Chlorocebus aethiops ; Hep G2 Cells ; Humans ; Paclitaxel/chemical synthesis ; Paclitaxel/isolation & purification ; Paclitaxel/pharmacology ; Porphyrins/chemical synthesis ; Porphyrins/pharmacology ; Vero Cells

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Informacja

Wyszukujesz frazę ""Mahmoud, M."" wg kryterium: Autor

Źródło danych

Ogranicz do:

Ogranicz do bazy

Typ dokumentu

Temat

Wydawca

Publikacja

Język

Rok publikacji