Anticancer Tungstenocenes with a Diverse Set of ( O,O -), ( O , S -) and ( O , N -) Chelates-A Detailed Biological Study Using an Improved Evaluation via 3D Spheroid Models.
Autorzy:
Cseh K; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Berasaluce I; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Fuchs V; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Banc A; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Schweikert A; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria.; Institute of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, A 1090 Vienna, Austria. Prado-Roller A; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Hejl M; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Wernitznig D; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Koellensperger G; Institute of Analytical Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 38, A 1090 Vienna, Austria. Jakupec MA; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Kandioller W; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. MalarekMS; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria. Keppler BK; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, A 1090 Vienna, Austria.
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Źródło:
Pharmaceutics [Pharmaceutics] 2023 Jul 03; Vol. 15 (7). Date of Electronic Publication: 2023 Jul 03.
Highly Cytotoxic Molybdenocenes with Strong Metabolic Effects Inhibit Tumour Growth in Mice.
Autorzy:
Fuchs V; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria. Cseh K; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria. Hejl M; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria. Vician P; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8 A, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria. Neuditschko B; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Meier-Menches SM; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.; Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Janker L; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.; Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Bileck A; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.; Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Gajic N; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria. Kronberger J; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria. Schaier M; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Neumayer S; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Köllensperger G; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Gerner C; Institute of Analytical Chemistry, University of Vienna, Währinger Straße 38, 1090, Vienna, Austria.; Joint Metabolome Facility, University of Vienna and Medical University of Vienna, Währinger Straße 38, 1090, Vienna, Austria. Berger W; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8 A, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria. Jakupec MA; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria. MalarekMS; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria. Keppler BK; Institute of Inorganic Chemistry, University of Vienna, Währinger Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', Währinger Straße 42, 1090, Vienna, Austria.
The First Anticancer Tris(pyrazolyl)borate Molybdenum(IV) Complexes: Tested in Vitro and in Vivo-A Comparison of O,O-, S,O-, and N,N-Chelate Effects.
Autorzy:
Berasaluce I; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Cseh K; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Roller A; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Hejl M; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Heffeter P; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090, Vienna, Austria. Berger W; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna, Borschkegasse 8a, 1090, Vienna, Austria. Jakupec MA; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Kandioller W; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. MalarekMS; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria. Keppler BK; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.; Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Waehringer Straße 42, 1090, Vienna, Austria.
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