Deciphering heterogeneity of septic shock patients using immune functional assays: a proof of concept study.
Autorzy :
Albert Vega C; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France. .; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France. . Oriol G; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France.; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France. Bartolo F; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France.; Soladis, Lyon, France. Lopez J; Hospices Civils de Lyon - Plateforme de Recherche de Transfert en Oncologie, Centre Hospitalier Lyon Sud, Pierre-Bénite, 69495, Lyon, France. Pachot A; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France. Rimmelé T; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, PI3, Claude Bernard Lyon 1 University-bioMérieux-Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437, Lyon, France.; Anesthesia and Critical Care Medicine Department, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. Venet F; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, PI3, Claude Bernard Lyon 1 University-bioMérieux-Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437, Lyon, France.; Immunology Laboratory, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. Leray V; Anesthesia and Critical Care Medicine Department, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. Monneret G; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, PI3, Claude Bernard Lyon 1 University-bioMérieux-Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437, Lyon, France.; Immunology Laboratory, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. Delwarde B; Anesthesia and Critical Care Medicine Department, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. Brengel-Pesce K; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France.; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France. Textoris J; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France.; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, PI3, Claude Bernard Lyon 1 University-bioMérieux-Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437, Lyon, France.; Anesthesia and Critical Care Medicine Department, Hôpital Edouard Herriot, Hospices Civils de Lyon, 69437, Lyon, France. MalletF; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France.; Open Innovation and Partnerships Department, bioMérieux S.A., Marcy l'Étoile, France.; EA 7426 Pathophysiology of Injury-Induced Immunosuppression, PI3, Claude Bernard Lyon 1 University-bioMérieux-Hospices Civils de Lyon, Hôpital Edouard Herriot, 69437, Lyon, France. Trouillet-Assant S; Laboratoire Commun de Recherche Hospices Civils de Lyon-bioMérieux, Joint Research Unit Hospices Civils de Lyon-bioMérieux, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Bâtiment 3F, Pierre-Bénite, 69495, Lyon, France.; CIRI, INSERM U1111, CNRS 5308, ENS, UCBL, Faculté de Médecine Lyon Est, Virpath - Université Lyon, 7 rue Guillaume Paradin, 69372, Lyon Cedex 08, France.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 30; Vol. 10 (1), pp. 16136. Date of Electronic Publication: 2020 Sep 30.
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