Informacja

Drogi użytkowniku, aplikacja do prawidłowego działania wymaga obsługi JavaScript. Proszę włącz obsługę JavaScript w Twojej przeglądarce.

Przeglądasz jako GOŚĆ

Wyszukujesz frazę ""Malonyl Coenzyme A"" wg kryterium: Temat


Tytuł :
Isoflavone malonyl-CoA acyltransferase GmMaT2 is involved in nodulation of soybean by modifying synthesis and secretion of isoflavones.
Autorzy :
Ahmad MZ; State Key Laboratory of Tea Plant Biology and Utilization, College of Tea and Food Science and Technology, Anhui Agricultural University, Hefei, China.
Zhang Y; State Key Laboratory of Tea Plant Biology and Utilization, College of Tea and Food Science and Technology, Anhui Agricultural University, Hefei, China.
Zeng X; College of Agronomy, Anhui Agricultural University, Hefei, China.
Li P; State Key Laboratory of Tea Plant Biology and Utilization, College of Tea and Food Science and Technology, Anhui Agricultural University, Hefei, China.
Wang X; College of Agronomy, Anhui Agricultural University, Hefei, China.
Benedito VA; Division of Plant & Soil Sciences, West Virginia University, Morgantown, WV, USA.
Zhao J; State Key Laboratory of Tea Plant Biology and Utilization, College of Tea and Food Science and Technology, Anhui Agricultural University, Hefei, China.
Pokaż więcej
Źródło :
Journal of experimental botany [J Exp Bot] 2021 Feb 24; Vol. 72 (4), pp. 1349-1369.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Isoflavones*
Plant Root Nodulation*
Soybeans*/enzymology
Soybeans*/genetics
Acyltransferases/*physiology
Malonyl Coenzyme A/*physiology
Acyltransferases/genetics ; Malonyl Coenzyme A/genetics
Czasopismo naukowe
Tytuł :
(p)ppGpp/GTP and Malonyl-CoA Modulate Staphylococcus aureus Adaptation to FASII Antibiotics and Provide a Basis for Synergistic Bi-Therapy.
Autorzy :
Pathania A; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France .
Anba-Mondoloni J; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France.
Gominet M; Unité de Biologie des Pathogènes à Gram-positif, CNRS UMR 2001, Institut Pasteur, Paris, France.
Halpern D; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France.
Dairou J; Université de Paris, CNRS UMR8601, Paris, France.
Dupont L; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France.
Lamberet G; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France.
Trieu-Cuot P; Unité de Biologie des Pathogènes à Gram-positif, CNRS UMR 2001, Institut Pasteur, Paris, France.
Gloux K; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France.
Gruss A; Micalis Institute, INRAE, AgroParisTech, Université Paris-Saclay, Jouy en Josas, France .
Pokaż więcej
Źródło :
MBio [mBio] 2021 Feb 02; Vol. 12 (1). Date of Electronic Publication: 2021 Feb 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Fatty Acids/*antagonists & inhibitors
Guanosine Pentaphosphate/*physiology
Guanosine Triphosphate/*physiology
Malonyl Coenzyme A/*physiology
Staphylococcus aureus/*drug effects
Adaptation, Physiological/drug effects ; Fatty Acids/biosynthesis ; Humans ; Malonyl Coenzyme A/analysis ; Mupirocin/pharmacology ; Phospholipids/biosynthesis ; Staphylococcal Infections/drug therapy ; Staphylococcus aureus/physiology
Czasopismo naukowe
Tytuł :
Ustethylin Biosynthesis Implies Phenethyl Derivative Formation in Aspergillus ustus .
Autorzy :
Zheng L; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Robert-Koch Straße 4, 35037 Marburg, Germany.
Yang Y; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Robert-Koch Straße 4, 35037 Marburg, Germany.
Wang H; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Robert-Koch Straße 4, 35037 Marburg, Germany.
Fan A; College of Life Science and Technology, Beijing University of Chemical Technology, North Third Ring Road 15, Chaoyang District, 100029 Beijing, China.
Zhang L; Key Laboratory of Tropical Marine Bio-resources, South China Sea Institute of Oceanology Chinese Academy of Sciences, 164 West Xingang Road, Guangzhou 510301, China.
Li SM; Institut für Pharmazeutische Biologie und Biotechnologie, Fachbereich Pharmazie, Philipps-Universität Marburg, Robert-Koch Straße 4, 35037 Marburg, Germany.
Pokaż więcej
Źródło :
Organic letters [Org Lett] 2020 Oct 16; Vol. 22 (20), pp. 7837-7841. Date of Electronic Publication: 2020 Oct 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acetyl Coenzyme A/*chemistry
Aspergillus/*chemistry
Malonyl Coenzyme A/*chemistry
Methyltransferases/*metabolism
Oxidoreductases/*metabolism
Polyketide Synthases/*metabolism
Acetyl Coenzyme A/metabolism ; Malonyl Coenzyme A/isolation & purification ; Malonyl Coenzyme A/metabolism ; Methyltransferases/chemistry ; Molecular Structure ; Oxidoreductases/chemistry ; Polyketide Synthases/chemistry
SCR Organism :
Aspergillus ustus
Czasopismo naukowe
Tytuł :
Gap junctions deliver malonyl-CoA from soma to germline to support embryogenesis in Caenorhabditis elegans .
Autorzy :
Starich TA; Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.
Bai X; National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, United States.
Greenstein D; Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, United States.
Pokaż więcej
Źródło :
ELife [Elife] 2020 Jul 31; Vol. 9. Date of Electronic Publication: 2020 Jul 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
MeSH Terms :
Caenorhabditis elegans/*embryology
Caenorhabditis elegans Proteins/*genetics
Embryonic Development/*genetics
Germ Cells/*growth & development
Malonyl Coenzyme A/*genetics
Animals ; Caenorhabditis elegans/enzymology ; Caenorhabditis elegans/genetics ; Caenorhabditis elegans Proteins/metabolism ; Embryo, Nonmammalian/embryology ; Embryo, Nonmammalian/metabolism ; Gap Junctions/physiology ; Gonads/growth & development ; Malonyl Coenzyme A/metabolism
Czasopismo naukowe
Tytuł :
Biotransformation of Benzoate to 2,4,6-Trihydroxybenzophenone by Engineered Escherichia coli .
Autorzy :
Klamrak A; Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Nabnueangsap J; Salaya Central Instrument Facility RSPG, Mahidol University, Nakhon Pathom 73170, Thailand.
Nualkaew N; Faculty of Pharmaceutical Sciences, Khon Kaen University, Khon Kaen 40002, Thailand.
Pokaż więcej
Źródło :
Molecules (Basel, Switzerland) [Molecules] 2021 May 08; Vol. 26 (9). Date of Electronic Publication: 2021 May 08.
Typ publikacji :
Journal Article
MeSH Terms :
Benzoates/*metabolism
Benzophenones/*metabolism
Escherichia coli/*genetics
Escherichia coli/*metabolism
Metabolic Engineering/*methods
Xanthones/*metabolism
Biotransformation ; Carbon-Carbon Ligases/metabolism ; Chromatography, Liquid ; Coenzyme A Ligases/metabolism ; Computer Simulation ; Culture Media ; Garcinia mangostana/enzymology ; Garcinia mangostana/genetics ; Malonyl Coenzyme A/metabolism ; Plasmids/genetics ; Rhodopseudomonas/enzymology ; Rhodopseudomonas/genetics ; Tandem Mass Spectrometry
SCR Organism :
Rhodopseudomonas palustris
Czasopismo naukowe
Tytuł :
Computationally-guided exchange of substrate selectivity motifs in a modular polyketide synthase acyltransferase.
Autorzy :
Kalkreuter E; Department of Chemistry, NC State University, Raleigh, NC, USA.; Comparative Medicine Institute, NC State University, Raleigh, NC, USA.; Department of Chemistry, The Scripps Research Institute, Jupiter, FL, USA.
Bingham KS; Department of Chemistry, NC State University, Raleigh, NC, USA.; UNC Chapel Hill School of Medicine, Chapel Hill, NC, USA.
Keeler AM; Department of Chemistry, NC State University, Raleigh, NC, USA.
Lowell AN; Life Sciences Institute, Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA.; Department of Chemistry, Virginia Tech, Blacksburg, VA, USA.
Schmidt JJ; Life Sciences Institute, Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA.
Sherman DH; Life Sciences Institute, Department of Medicinal Chemistry, University of Michigan, Ann Arbor, MI, USA.; Department of Chemistry, Department of Microbiology & Immunology, University of Michigan, Ann Arbor, MI, USA.
Williams GJ; Department of Chemistry, NC State University, Raleigh, NC, USA. .; Comparative Medicine Institute, NC State University, Raleigh, NC, USA. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2021 Apr 13; Vol. 12 (1), pp. 2193. Date of Electronic Publication: 2021 Apr 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Acyltransferases/*chemistry
Acyltransferases/*metabolism
Polyketide Synthases/*chemistry
Polyketide Synthases/*metabolism
Acyltransferases/genetics ; Catalytic Domain ; Malonyl Coenzyme A ; Molecular Dynamics Simulation ; Mutagenesis ; Polyketide Synthases/genetics ; Polyketides ; Protein Engineering ; Secondary Metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł :
Carnitine palmitoyltransferase 1C negatively regulates the endocannabinoid hydrolase ABHD6 in mice, depending on nutritional status.
Autorzy :
Miralpeix C; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.; INSERM, Neurocentre Magendie, University of Bordeaux, Bordeaux, France.
Reguera AC; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Fosch A; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Casas M; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.; Department of Physiology and Membrane Biology, University of California, Davis, Davis, California, USA.
Lillo J; Molecular Neurobiology Laboratory, Department of Biochemistry and Physiology, Faculty of Biology, University of Barcelona, Barcelona, Spain.
Navarro G; INSERM, Neurocentre Magendie, University of Bordeaux, Bordeaux, France.
Franco R; INSERM, Neurocentre Magendie, University of Bordeaux, Bordeaux, France.
Casas J; Department on Biomedical Chemistry, Research Unit of BioActive Molecules, Institut de Química Avançada de Catalunya (IQAC), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III, Madrid, Spain.
Alexander SPH; School of Life Sciences, University of Nottingham, Nottingham, UK.
Casals N; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.
Rodríguez-Rodríguez R; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Pokaż więcej
Źródło :
British journal of pharmacology [Br J Pharmacol] 2021 Apr; Vol. 178 (7), pp. 1507-1523. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carnitine O-Palmitoyltransferase*/genetics
Nutritional Status*
Monoacylglycerol Lipases/*metabolism
Animals ; Hydrolases ; Malonyl Coenzyme A ; Mice
Czasopismo naukowe
Tytuł :
Structures of LnmK, a Bifunctional Acyltransferase/Decarboxylase, with Substrate Analogues Reveal the Basis for Selectivity and Stereospecificity.
Autorzy :
Stunkard LM; Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907, United States.
Kick BJ; Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907, United States.
Lohman JR; Department of Biochemistry, Purdue University, West Lafayette, Indiana 47907, United States.; Purdue Center for Cancer Research, Purdue University, West Lafayette, Indiana 47907, United States.
Pokaż więcej
Źródło :
Biochemistry [Biochemistry] 2021 Feb 09; Vol. 60 (5), pp. 365-372. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Acyltransferases/*chemistry
Carboxy-Lyases/*chemistry
Acyl Carrier Protein/metabolism ; Acyl Coenzyme A/chemistry ; Carbon-Carbon Ligases/chemistry ; Catalysis ; Catalytic Domain ; Malonyl Coenzyme A/metabolism ; Streptomyces/metabolism ; Streptomyces coelicolor/metabolism ; Substrate Specificity
SCR Organism :
Streptomyces atroolivaceus
Czasopismo naukowe
Tytuł :
Tropane alkaloids biosynthesis involves an unusual type III polyketide synthase and non-enzymatic condensation.
Autorzy :
Huang JP; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Fang C; The Key Laboratory of Synthetic Biology, and CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China.
Ma X; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.; School of Chemistry and Chemical Engineering, Sichuan University of Science & Engineering, Zigong, 643000, China.
Wang L; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Yang J; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Luo J; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Yan Y; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China.
Zhang Y; The Key Laboratory of Synthetic Biology, and CAS Center for Excellence in Molecular Plant Sciences, Institute of Plant Physiology and Ecology, Chinese Academy of Sciences, Shanghai, 200032, China. .
Huang SX; State Key Laboratory of Phytochemistry and Plant Resources in West China, and CAS Center for Excellence in Molecular Plant Sciences, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, 650201, China. .
Pokaż więcej
Źródło :
Nature communications [Nat Commun] 2019 Sep 06; Vol. 10 (1), pp. 4036. Date of Electronic Publication: 2019 Sep 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Malonyl Coenzyme A/*metabolism
Plant Proteins/*metabolism
Polyketide Synthases/*metabolism
Pyrroles/*metabolism
Solanaceous Alkaloids/*metabolism
Tropanes/*metabolism
Amino Acid Sequence ; Biocatalysis ; Chromatography, Liquid/methods ; Crystallography, X-Ray ; Malonyl Coenzyme A/chemistry ; Models, Chemical ; Molecular Structure ; Phylogeny ; Plant Proteins/classification ; Plant Proteins/genetics ; Polyketide Synthases/chemistry ; Polyketide Synthases/genetics ; Pyrroles/chemistry ; Sequence Homology, Amino Acid ; Solanaceous Alkaloids/chemistry ; Tandem Mass Spectrometry/methods ; Tropanes/chemistry
Czasopismo naukowe
Tytuł :
Modulation of the central carbon metabolism of Corynebacterium glutamicum improves malonyl-CoA availability and increases plant polyphenol synthesis.
Autorzy :
Milke L; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Ferreira P; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.
Kallscheuer N; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Braga A; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.
Vogt M; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Kappelmann J; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Oliveira J; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.
Silva AR; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.
Rocha I; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.; Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal.
Bott M; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Noack S; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Faria N; Biotempo, Guimarães, Portugal.; Centre of Biological Engineering, University of Minho-Campus de Gualtar, Braga, Portugal.
Marienhagen J; Institute of Bio- and Geosciences, IBG-1: Biotechnology, Forschungszentrum Jülich, Jülich, Germany.
Pokaż więcej
Źródło :
Biotechnology and bioengineering [Biotechnol Bioeng] 2019 Jun; Vol. 116 (6), pp. 1380-1391. Date of Electronic Publication: 2019 Feb 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Corynebacterium glutamicum*/genetics
Corynebacterium glutamicum*/metabolism
Malonyl Coenzyme A*/analysis
Malonyl Coenzyme A*/genetics
Malonyl Coenzyme A*/metabolism
Phytochemicals*/analysis
Phytochemicals*/metabolism
Polyphenols*/analysis
Polyphenols*/metabolism
Metabolic Engineering/*methods
Bioreactors ; Citrate (si)-Synthase/metabolism ; Citric Acid Cycle/genetics ; Flavanones ; Resveratrol
Czasopismo naukowe
Tytuł :
Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli.
Autorzy :
Kalkreuter E; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.; Comparative Medicine Institute , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Keeler AM; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Malico AA; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Bingham KS; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Gayen AK; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Williams GJ; Department of Chemistry , North Carolina State University , Raleigh , North Carolina 27695 , United States.; Comparative Medicine Institute , North Carolina State University , Raleigh , North Carolina 27695 , United States.
Pokaż więcej
Źródło :
ACS synthetic biology [ACS Synth Biol] 2019 Jun 21; Vol. 8 (6), pp. 1391-1400. Date of Electronic Publication: 2019 May 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Biosensing Techniques/*methods
Malonyl Coenzyme A/*analysis
Polyketide Synthases/*metabolism
Protein Engineering/*methods
Escherichia coli/genetics ; Escherichia coli Proteins/genetics ; Escherichia coli Proteins/isolation & purification ; Escherichia coli Proteins/metabolism ; Malonyl Coenzyme A/metabolism ; Metabolic Networks and Pathways ; Polyketides/metabolism ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Recombinant Proteins/metabolism ; Synthetic Biology ; Transcription Factors/genetics ; Transcription Factors/isolation & purification ; Transcription Factors/metabolism
Czasopismo naukowe
Tytuł :
Role of the malonyl-CoA synthetase ACSF3 in mitochondrial metabolism.
Autorzy :
Bowman CE; Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA.
Wolfgang MJ; Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA. Electronic address: .
Pokaż więcej
Źródło :
Advances in biological regulation [Adv Biol Regul] 2019 Jan; Vol. 71, pp. 34-40. Date of Electronic Publication: 2018 Sep 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Citric Acid Cycle/*physiology
Coenzyme A Ligases/*metabolism
Malonyl Coenzyme A/*metabolism
Mitochondria/*enzymology
Animals ; Coenzyme A Ligases/genetics ; Humans ; Malonates/metabolism ; Malonyl Coenzyme A/genetics ; Mitochondria/genetics
Czasopismo naukowe
Tytuł :
A bio-inspired cell-free system for cannabinoid production from inexpensive inputs.
Autorzy :
Valliere MA; Department of Chemistry and Biochemistry, Molecular Biology Institute, UCLA-DOE Institute, University of California, Los Angeles, CA, USA.; Conagen, Inc., Bedford, MA, USA.
Korman TP; Department of Chemistry and Biochemistry, Molecular Biology Institute, UCLA-DOE Institute, University of California, Los Angeles, CA, USA.; Invizyne Technologies, Inc., Monrovia, CA, USA.
Arbing MA; Department of Chemistry and Biochemistry, Molecular Biology Institute, UCLA-DOE Institute, University of California, Los Angeles, CA, USA.
Bowie JU; Department of Chemistry and Biochemistry, Molecular Biology Institute, UCLA-DOE Institute, University of California, Los Angeles, CA, USA. .
Pokaż więcej
Źródło :
Nature chemical biology [Nat Chem Biol] 2020 Dec; Vol. 16 (12), pp. 1427-1433. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Cannabinoids/*biosynthesis
Cell-Free System/*metabolism
Malonyl Coenzyme A/*metabolism
Metabolic Engineering/*methods
Polyketides/*metabolism
Terpenes/*metabolism
Adenosine Triphosphate/biosynthesis ; Benzoates/isolation & purification ; Benzoates/metabolism ; Cannabinoids/isolation & purification ; Cell-Free System/chemistry ; Escherichia coli/enzymology ; Escherichia coli/genetics ; Gene Expression ; Humans ; Kinetics ; Metabolic Engineering/economics ; Organophosphates/metabolism ; Plasmids/chemistry ; Plasmids/metabolism ; Polyketides/chemistry ; Recombinant Proteins/biosynthesis ; Recombinant Proteins/genetics ; Recombinant Proteins/isolation & purification ; Terpenes/chemistry ; Thermodynamics
Czasopismo naukowe
Tytuł :
Sensing of nutrients by CPT1C controls SAC1 activity to regulate AMPA receptor trafficking.
Autorzy :
Casas M; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Fadó R; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Domínguez JL; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Roig A; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.
Kaku M; Department of Food and Life Science, Ibaraki University College of Agriculture, Ami, Ibaraki, Japan.
Chohnan S; Department of Food and Life Science, Ibaraki University College of Agriculture, Ami, Ibaraki, Japan.
Solé M; Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.
Unzeta M; Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.
Miñano-Molina AJ; Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain.
Rodríguez-Álvarez J; Biochemistry and Molecular Biology Department, Institute of Neurosciences, Universitat Autònoma de Barcelona, Bellaterra, Barcelona, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas, Madrid, Spain.; Department of Neuroscience, Albert Einstein College of Medicine, New York, NY.
Dickson EJ; Department of Physiology and Membrane Biology, University of California, School of Medicine, Davis, CA.
Casals N; Basic Sciences Department, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Spain.; Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid, Spain.
Pokaż więcej
Źródło :
The Journal of cell biology [J Cell Biol] 2020 Oct 05; Vol. 219 (10).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Carnitine O-Palmitoyltransferase/*genetics
Membrane Proteins/*genetics
Neurons/*metabolism
Receptors, AMPA/*genetics
Animals ; Brain/metabolism ; Glucose/metabolism ; Humans ; Malonyl Coenzyme A/genetics ; Mice ; Nutrients/metabolism ; Phosphatidylinositol Phosphates/metabolism ; Protein Transport/genetics ; Synaptic Transmission/genetics
Czasopismo naukowe
Tytuł :
Synthetic biology, systems biology, and metabolic engineering of Yarrowia lipolytica toward a sustainable biorefinery platform.
Autorzy :
Ma J; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.
Gu Y; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.
Marsafari M; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA.; Department of Agronomy and Plant Breeding, University of Guilan, Rasht, Islamic Republic of Iran.
Xu P; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland, Baltimore County, Baltimore, MD, 21250, USA. .
Pokaż więcej
Źródło :
Journal of industrial microbiology & biotechnology [J Ind Microbiol Biotechnol] 2020 Oct; Vol. 47 (9-10), pp. 845-862. Date of Electronic Publication: 2020 Jul 04.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Metabolic Engineering*
Synthetic Biology*
Systems Biology*
Yarrowia*/metabolism
Acetyl Coenzyme A/metabolism ; Acyl Coenzyme A ; Fatty Acids/metabolism ; Lipids ; Malonyl Coenzyme A/metabolism ; Polyketides/metabolism ; Terpenes/metabolism
Czasopismo naukowe
Tytuł :
Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA.
Autorzy :
Shi X; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Zhou X; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Wang J; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Zhang D; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Huang K; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Li X; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China.
Yang G; Laboratory of Animal Fat Deposition & Muscle Development, Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University Yangling, Shaanxi 712100, China. Electronic address: .
Pokaż więcej
Źródło :
Life sciences [Life Sci] 2020 Oct 01; Vol. 258, pp. 118240. Date of Electronic Publication: 2020 Aug 08.
Typ publikacji :
Journal Article
MeSH Terms :
Acetyl Coenzyme A/*biosynthesis
Carnitine O-Palmitoyltransferase/*antagonists & inhibitors
Lipogenesis/*drug effects
Malonyl Coenzyme A/*biosynthesis
Tartronates/*pharmacology
Up-Regulation/*drug effects
3T3-L1 Cells ; Animals ; Carnitine O-Palmitoyltransferase/metabolism ; Diet, High-Fat/adverse effects ; Lipogenesis/physiology ; Male ; Mice ; Mice, Inbred C57BL ; Up-Regulation/physiology
Czasopismo naukowe
Tytuł :
Coupling metabolic addiction with negative autoregulation to improve strain stability and pathway yield.
Autorzy :
Lv Y; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD, 21250, USA; School of Chemical Engineering, Zhengzhou University, Zhengzhou, Henan, 450001, China; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu, 214122, China.
Gu Y; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD, 21250, USA; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu, 214122, China.
Xu J; School of Chemical Engineering, Zhengzhou University, Zhengzhou, Henan, 450001, China. Electronic address: .
Zhou J; National Engineering Laboratory for Cereal Fermentation Technology, Jiangnan University, Wuxi, Jiangsu, 214122, China. Electronic address: .
Xu P; Department of Chemical, Biochemical and Environmental Engineering, University of Maryland Baltimore County, Baltimore, MD, 21250, USA. Electronic address: .
Pokaż więcej
Źródło :
Metabolic engineering [Metab Eng] 2020 Sep; Vol. 61, pp. 79-88. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Homeostasis*
Metabolic Engineering*
Yarrowia*/genetics
Yarrowia*/metabolism
Malonyl Coenzyme A/genetics ; Malonyl Coenzyme A/metabolism
Czasopismo naukowe
Tytuł :
A Single Metabolite which Modulates Lipid Metabolism Alters Hematopoietic Stem/Progenitor Cell Behavior and Promotes Lymphoid Reconstitution.
Autorzy :
Giger S; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Kovtonyuk LV; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Utz SG; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Ramosaj M; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland.
Kovacs WJ; Institute of Molecular Health Sciences, ETH Zurich, Zurich, Switzerland.
Schmid E; SIB Swiss Institute of Bioinformatics, University of Lausanne, Lausanne, Switzerland.
Ioannidis V; SIB Swiss Institute of Bioinformatics, University of Lausanne, Lausanne, Switzerland.
Greter M; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland.
Manz MG; Department of Medical Oncology and Hematology, University Hospital Zurich and University of Zurich, Zurich, Switzerland.
Lutolf MP; Institute of Bioengineering, Ecole Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.
Jessberger S; Brain Research Institute, University of Zurich, Zurich, Switzerland. Electronic address: .
Knobloch M; Department of Biomedical Sciences, University of Lausanne, Lausanne, Switzerland. Electronic address: .
Pokaż więcej
Źródło :
Stem cell reports [Stem Cell Reports] 2020 Sep 08; Vol. 15 (3), pp. 566-576. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Lipid Metabolism*/genetics
Metabolome*/genetics
Hematopoietic Stem Cells/*cytology
Hematopoietic Stem Cells/*metabolism
Lymphocytes/*cytology
Animals ; Cell Differentiation/genetics ; Cell Lineage/genetics ; Cell Proliferation/genetics ; Cells, Cultured ; Fatty Acids/metabolism ; Gene Expression Regulation ; Lymphocytes/metabolism ; Malonyl Coenzyme A/metabolism ; Mice, Inbred C57BL ; Oxidation-Reduction
Czasopismo naukowe
Tytuł :
A Korean child diagnosed with malonic aciduria harboring a novel start codon mutation following presentation with dilated cardiomyopathy.
Autorzy :
Lee SH; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Ko JM; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Song MK; Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea.
Song J; Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.
Park KS; Department of Laboratory Medicine, Kyung Hee University School of Medicine, Seoul, Korea.
Pokaż więcej
Źródło :
Molecular genetics & genomic medicine [Mol Genet Genomic Med] 2020 Sep; Vol. 8 (9), pp. e1379. Date of Electronic Publication: 2020 Jun 30.
Typ publikacji :
Case Reports; Journal Article
MeSH Terms :
Mutation*
Carboxy-Lyases/*deficiency
Cardiomyopathy, Dilated/*genetics
Metabolism, Inborn Errors/*genetics
Carboxy-Lyases/genetics ; Cardiomyopathy, Dilated/pathology ; Codon, Initiator ; Humans ; Infant ; Male ; Malonates/metabolism ; Malonyl Coenzyme A/genetics ; Metabolism, Inborn Errors/pathology ; Methylmalonic Acid ; Phenotype
SCR Disease Name :
Malonic aciduria
Czasopismo naukowe
Tytuł :
Efficient heterologous production of atrochrysone carboxylic acid-related polyketides in an Aspergillus oryzae host with enhanced malonyl-coenzyme A supply.
Autorzy :
Kan E; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo.; Noda Institute for Scientific Research.
Katsuyama Y; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo.; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo.
Maruyama JI; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo.; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo.
Tamano K; Bioproduction Research Institute, National Institute of Advanced Industrial Science and Technology (AIST).
Koyama Y; Noda Institute for Scientific Research.
Ohnishi Y; Department of Biotechnology, Graduate School of Agricultural and Life Sciences, The University of Tokyo.; Collaborative Research Institute for Innovative Microbiology, The University of Tokyo.
Pokaż więcej
Źródło :
The Journal of general and applied microbiology [J Gen Appl Microbiol] 2020 Aug 26; Vol. 66 (3), pp. 195-199. Date of Electronic Publication: 2019 Nov 27.
Typ publikacji :
Journal Article
MeSH Terms :
Aspergillus oryzae/*genetics
Aspergillus oryzae/*metabolism
Malonyl Coenzyme A/*metabolism
Polyketides/*metabolism
Curcumin/metabolism ; Gene Deletion ; Genes, Fungal ; Polyketide Synthases/metabolism
Czasopismo naukowe

Ta witryna wykorzystuje pliki cookies do przechowywania informacji na Twoim komputerze. Pliki cookies stosujemy w celu świadczenia usług na najwyższym poziomie, w tym w sposób dostosowany do indywidualnych potrzeb. Korzystanie z witryny bez zmiany ustawień dotyczących cookies oznacza, że będą one zamieszczane w Twoim komputerze. W każdym momencie możesz dokonać zmiany ustawień dotyczących cookies