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Tytuł:
Molecular response to PARP1 inhibition in ovarian cancer cells as determined by mass spectrometry based proteomics.
Autorzy:
Franz A; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02115, USA. .; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA. .; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA. .
Coscia F; Proteomics Program, NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.
Shen C; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA.
Charaoui L; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02115, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA.
Mann M; Proteomics Program, NNF Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, 2200, Copenhagen, Denmark.; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, 82152, Martinsried, Germany.
Sander C; Department of Data Science, Dana-Farber Cancer Institute, Boston, MA, 02115, USA. .; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA. .; Broad Institute of Harvard and MIT, Cambridge, MA, 02142, USA. .
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Źródło:
Journal of ovarian research [J Ovarian Res] 2021 Oct 22; Vol. 14 (1), pp. 140. Date of Electronic Publication: 2021 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Mass Spectrometry/*methods
Ovarian Neoplasms/*drug therapy
Poly(ADP-ribose) Polymerase Inhibitors/*therapeutic use
Proteomics/*methods
Female ; Humans ; Ovarian Neoplasms/diagnostic imaging ; Poly(ADP-ribose) Polymerase Inhibitors/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Discovery of RSV-Induced BRD4 Protein Interactions Using Native Immunoprecipitation and Parallel Accumulation-Serial Fragmentation (PASEF) Mass Spectrometry.
Autorzy:
Mann M; Department of Medicine, University of Wisconsin-Madison School of Medicine and Public Health (SMPH), Madison, WI 53705, USA.
Roberts DS; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Zhu Y; Human Proteomics Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Li Y; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77550, USA.
Zhou J; Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77550, USA.
Ge Y; Department of Chemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.; Human Proteomics Program, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI 53705, USA.
Brasier AR; Institute for Clinical and Translational Research (ICTR), University of Wisconsin-Madison, Madison, WI 53705, USA.
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Źródło:
Viruses [Viruses] 2021 Mar 11; Vol. 13 (3). Date of Electronic Publication: 2021 Mar 11.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Host Microbial Interactions*
Cell Cycle Proteins/*genetics
Cell Cycle Proteins/*metabolism
Immunoprecipitation/*methods
Mass Spectrometry/*methods
Respiratory Syncytial Virus, Human/*genetics
Respiratory Syncytial Virus, Human/*immunology
Transcription Factors/*genetics
Transcription Factors/*metabolism
A549 Cells ; Alveolar Epithelial Cells/immunology ; Alveolar Epithelial Cells/virology ; Cell Cycle Proteins/antagonists & inhibitors ; Cell Cycle Proteins/immunology ; Gene Expression Regulation ; Humans ; Immunity, Innate/genetics ; Mass Spectrometry/classification ; Proteomics ; Respiratory Syncytial Virus Infections/virology ; Respiratory Syncytial Virus, Human/metabolism ; Signal Transduction ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/immunology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A mass spectrometry guided approach for the identification of novel vaccine candidates in gram-negative pathogens.
Autorzy:
Hornburg D; Max-Planck-Institute for Biochemistry, Martinsried, Germany.; Stanford University, School of Medicine, San Francisco, USA.
Kruse T; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.; ImevaX GmbH, Munich, Germany.
Anderl F; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.; ImevaX GmbH, Munich, Germany.
Daschkin C; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.
Semper RP; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.; German Center for infection research, partner site Munich, Munich, Germany.
Klar K; ImevaX GmbH, Munich, Germany.
Guenther A; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.
Mejías-Luque R; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany.; German Center for infection research, partner site Munich, Munich, Germany.
Schneiderhan-Marra N; NMI Natural and Medical Sciences Institute, University of Tübingen, Reutlingen, Germany.
Mann M; Max-Planck-Institute for Biochemistry, Martinsried, Germany.
Meissner F; Max-Planck-Institute for Biochemistry, Martinsried, Germany. .
Gerhard M; Institut für Medizinische Mikrobiologie, Immunologie und Hygiene, Technische Universität München, Munich, Germany. .; ImevaX GmbH, Munich, Germany. .; German Center for infection research, partner site Munich, Munich, Germany. .
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Źródło:
Scientific reports [Sci Rep] 2019 Nov 22; Vol. 9 (1), pp. 17401. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bacterial Vaccines*/chemistry
Bacterial Vaccines*/immunology
Gram-Negative Bacteria*/immunology
Mass Spectrometry*
Antigens, Bacterial/chemistry ; Antigens, Bacterial/immunology ; Antigens, Surface/chemistry ; Antigens, Surface/immunology ; Bacterial Proteins/chemistry ; Bacterial Proteins/immunology ; Computational Biology/methods ; Proteomics/methods ; Reproducibility of Results
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Proteomics reveals the effects of sustained weight loss on the human plasma proteome.
Autorzy:
Geyer PE; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.; NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Wewer Albrechtsen NJ; NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Tyanova S; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Grassl N; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Iepsen EW; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Lundgren J; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Madsbad S; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Endocrinology, Hvidovre University Hospital, Hvidovre, Denmark.
Holst JJ; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Torekov SS; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; NNF Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Mann M; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany .; NNF Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Molecular systems biology [Mol Syst Biol] 2016 Dec 22; Vol. 12 (12), pp. 901. Date of Electronic Publication: 2016 Dec 22.
Typ publikacji:
Journal Article
MeSH Terms:
Weight Loss*
Mass Spectrometry/*methods
Obesity/*diet therapy
Proteomics/*methods
Adult ; Apolipoproteins/blood ; Caloric Restriction ; Eye Proteins/blood ; Gene Expression Regulation ; Humans ; Insulin Resistance ; Longitudinal Studies ; Middle Aged ; Nerve Growth Factors/blood ; Obesity/metabolism ; Plasma/metabolism ; Serpins/blood ; Young Adult
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Acetylation site specificities of lysine deacetylase inhibitors in human cells.
Autorzy:
Schölz C; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Weinert BT; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Wagner SA; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Beli P; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Miyake Y; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Qi J; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
Jensen LJ; Department of Protein Science and Technology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Streicher W; Department of Disease Systems Biology, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
McCarthy AR; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Westwood NJ; School of Chemistry and Biomedical Sciences Research Complex, EaStCHEM, University of St. Andrews, St. Andrews, Scotland, UK.
Lain S; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden.
Cox J; Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany.
Matthias P; Friedrich Miescher Institute for Biomedical Research, Basel, Switzerland.
Mann M; Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany.
Bradner JE; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, USA.
Choudhary C; Department of Proteomics, The Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
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Źródło:
Nature biotechnology [Nat Biotechnol] 2015 Apr; Vol. 33 (4), pp. 415-23. Date of Electronic Publication: 2015 Mar 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Enzyme Inhibitors/*chemistry
Histone Deacetylase Inhibitors/*chemistry
Histone Deacetylases/*chemistry
Mass Spectrometry/*methods
Peptide Mapping/*methods
Protein Interaction Mapping/*methods
Acetylation ; Amino Acid Sequence ; Binding Sites ; Cells, Cultured ; Humans ; Molecular Sequence Data ; Protein Binding
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A large synthetic peptide and phosphopeptide reference library for mass spectrometry-based proteomics.
Autorzy:
Marx H; Technische Universität München, Freising, Germany.
Lemeer S
Schliep JE
Matheron L
Mohammed S
Cox J
Mann M
Heck AJ
Kuster B
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Źródło:
Nature biotechnology [Nat Biotechnol] 2013 Jun; Vol. 31 (6), pp. 557-64. Date of Electronic Publication: 2013 May 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Peptide Library*
Mass Spectrometry/*methods
Peptides/*genetics
Phosphopeptides/*genetics
Proteomics/*methods
Algorithms ; Humans ; Peptides/chemical synthesis ; Phosphopeptides/chemical synthesis ; Phosphorylation ; Proteomics/standards ; Reference Standards ; Software
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Direct proteomic quantification of the secretome of activated immune cells.
Autorzy:
Meissner F; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Scheltema RA
Mollenkopf HJ
Mann M
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Źródło:
Science (New York, N.Y.) [Science] 2013 Apr 26; Vol. 340 (6131), pp. 475-8.
Typ publikacji:
Journal Article
MeSH Terms:
Macrophage Activation*
Macrophages/*immunology
Mass Spectrometry/*methods
Proteins/*metabolism
Proteome/*metabolism
Toll-Like Receptor 4/*agonists
Animals ; Lipopolysaccharides/immunology ; Mice ; Mice, Knockout ; Proteins/genetics ; Proteome/genetics ; Proteomics ; Transcription, Genetic ; Transcriptome
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Large-scale phosphosite quantification in tissues by a spike-in SILAC method.
Autorzy:
Monetti M; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany.
Nagaraj N
Sharma K
Mann M
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Źródło:
Nature methods [Nat Methods] 2011 Jul 10; Vol. 8 (8), pp. 655-8. Date of Electronic Publication: 2011 Jul 10.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Insulin/*pharmacology
Isotope Labeling/*methods
Liver/*metabolism
Mass Spectrometry/*methods
Phosphites/*metabolism
Cell Line ; Cells, Cultured ; Liver/drug effects
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mass spectrometry in high-throughput proteomics: ready for the big time.
Autorzy:
Nilsson T; Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada. />Mann M
Aebersold R
Yates JR 3rd
Bairoch A
Bergeron JJ
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Źródło:
Nature methods [Nat Methods] 2010 Sep; Vol. 7 (9), pp. 681-5.
Typ publikacji:
Journal Article
MeSH Terms:
Mass Spectrometry/*trends
Proteome/*analysis
Proteomics/*methods
Databases, Protein ; Humans ; Quality Control ; Reproducibility of Results ; Sensitivity and Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comparative analysis to guide quality improvements in proteomics.
Autorzy:
Mann M; Max Planck Institute for Biochemistry, Mantrinsried, Germany.
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Źródło:
Nature methods [Nat Methods] 2009 Oct; Vol. 6 (10), pp. 717-19.
Typ publikacji:
Journal Article
MeSH Terms:
Mass Spectrometry/*standards
Proteomics/*standards
Algorithms ; Biology/trends ; Computational Biology ; Evaluation Studies as Topic ; Laboratories/standards ; Mass Spectrometry/methods ; Proteomics/trends ; Quality Control
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Universal sample preparation method for proteome analysis.
Autorzy:
Wiśniewski JR; Department of Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Martinsried, Germany. />Zougman A
Nagaraj N
Mann M
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Źródło:
Nature methods [Nat Methods] 2009 May; Vol. 6 (5), pp. 359-62. Date of Electronic Publication: 2009 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Analytic Sample Preparation Methods/*methods
Mass Spectrometry/*methods
Proteome/*analysis
Proteomics/*methods
Animals ; Brain Chemistry ; Endopeptidases/chemistry ; HeLa Cells ; Humans ; Iodoacetamide/chemistry ; Liver/chemistry ; Mice ; Mitochondria/chemistry ; Proteome/chemistry ; Sodium Dodecyl Sulfate/chemistry ; Tandem Mass Spectrometry/methods ; Ultrafiltration/methods ; Urea/chemistry
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification.
Autorzy:
Cox J; Department for Proteomics and Signal Transduction, Max-Planck Institute for Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany. />Mann M
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Źródło:
Nature biotechnology [Nat Biotechnol] 2008 Dec; Vol. 26 (12), pp. 1367-72. Date of Electronic Publication: 2008 Nov 30.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Computational Biology/*methods
Mass Spectrometry/*methods
Peptides/*analysis
Proteins/*analysis
Proteomics/*methods
Algorithms ; Databases, Protein ; HeLa Cells ; Humans ; Peptides/chemistry ; Proteins/chemistry ; Proteome/analysis ; Proteome/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Comprehensive mass-spectrometry-based proteome quantification of haploid versus diploid yeast.
Autorzy:
de Godoy LM; Proteomics and Signal Transduction, Max-Planck-Institute for Biochemistry, Am Klopferspitz 18, D-82152 Martinsried, Germany.
Olsen JV
Cox J
Nielsen ML
Hubner NC
Fröhlich F
Walther TC
Mann M
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Źródło:
Nature [Nature] 2008 Oct 30; Vol. 455 (7217), pp. 1251-4. Date of Electronic Publication: 2008 Sep 28.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diploidy*
Haploidy*
Mass Spectrometry/*methods
Proteome/*analysis
Proteomics/*methods
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*analysis
Gene Expression Profiling ; Genes, Fungal/genetics ; Oligonucleotide Array Sequence Analysis ; Open Reading Frames ; Proteome/genetics ; RNA, Fungal/analysis ; RNA, Fungal/genetics ; Retroelements/genetics ; Saccharomyces cerevisiae/cytology ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Staining and Labeling ; Transcription, Genetic/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Iodoacetamide-induced artifact mimics ubiquitination in mass spectrometry.
Autorzy:
Nielsen ML
Vermeulen M
Bonaldi T
Cox J
Moroder L
Mann M
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Źródło:
Nature methods [Nat Methods] 2008 Jun; Vol. 5 (6), pp. 459-60.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Artifacts*
Alkylating Agents/*pharmacology
Iodoacetamide/*pharmacology
Mass Spectrometry/*methods
Ubiquitin/*chemistry
Acetamides/chemistry ; Alkylating Agents/chemistry ; Animals ; Histones/chemistry ; Humans ; Lysine/chemistry ; Models, Biological ; Peptide Hydrolases/chemistry ; Peptides/chemistry ; Protein Structure, Tertiary ; Trypsin/chemistry
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Higher-energy C-trap dissociation for peptide modification analysis.
Autorzy:
Olsen JV; Department for Proteomics and Signal Transduction, Max Planck Institute for Biochemistry, Am Klopferspitz 18, D-82131 Martinsried, Germany.
Macek B
Lange O
Makarov A
Horning S
Mann M
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Źródło:
Nature methods [Nat Methods] 2007 Sep; Vol. 4 (9), pp. 709-12. Date of Electronic Publication: 2007 Aug 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mass Spectrometry/*methods
Peptide Fragments/*chemistry
Proteomics/*methods
Tandem Mass Spectrometry/*methods
Mass Spectrometry/instrumentation ; Protein Conformation ; Proteomics/instrumentation ; Tandem Mass Spectrometry/instrumentation
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
A mass spectrometry-friendly database for cSNP identification.
Autorzy:
Schandorff S
Olsen JV
Bunkenborg J
Blagoev B
Zhang Y
Andersen JS
Mann M
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Źródło:
Nature methods [Nat Methods] 2007 Jun; Vol. 4 (6), pp. 465-6.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Genetic*
Mass Spectrometry/*methods
Polymorphism, Single Nucleotide/*genetics
Amino Acid Sequence ; Breast Neoplasms/metabolism ; Cell Line, Tumor ; Humans
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.
Autorzy:
Ong SE; Center for Experimental BioInformatics, University of Southern Denmark, Odense M 5230, Denmark.
Mittler G
Mann M
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Źródło:
Nature methods [Nat Methods] 2004 Nov; Vol. 1 (2), pp. 119-26. Date of Electronic Publication: 2004 Oct 21.
Typ publikacji:
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't; Validation Study
MeSH Terms:
Algorithms*
Chromatography, Liquid/*methods
Isotope Labeling/*methods
Mass Spectrometry/*methods
Methionine/*metabolism
Neoplasm Proteins/*metabolism
Proteome/*metabolism
Binding Sites ; Carbon Isotopes ; Gene Expression Profiling/methods ; HeLa Cells ; Humans ; Methionine/analysis ; Methylation ; Neoplasm Proteins/analysis ; Protein Binding ; Proteome/analysis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics.
Autorzy:
Blagoev B
Ong SE
Kratchmarova I
Mann M
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Źródło:
Nature biotechnology [Nat Biotechnol] 2004 Sep; Vol. 22 (9), pp. 1139-45. Date of Electronic Publication: 2004 Aug 15.
Typ publikacji:
Letter; Research Support, Non-U.S. Gov't
MeSH Terms:
ErbB Receptors/*metabolism
Gene Expression Regulation/*physiology
Mass Spectrometry/*methods
Phosphotyrosine/*metabolism
Proteome/*metabolism
Proteomics/*methods
Signal Transduction/*physiology
Epidermal Growth Factor/pharmacology ; Gene Expression Regulation/drug effects ; HeLa Cells ; Humans ; Isotope Labeling/methods ; Kinetics ; Oxidative Phosphorylation ; Signal Transduction/drug effects ; Time Factors
Raport
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Mass spectrometry-based proteomics.
Autorzy:
Aebersold R; Institute for Systems Biology, 1441 North 34th Street, Seattle, Washington 98103-8904, USA. />Mann M
Pokaż więcej
Źródło:
Nature [Nature] 2003 Mar 13; Vol. 422 (6928), pp. 198-207.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms:
Mass Spectrometry/*instrumentation
Mass Spectrometry/*methods
Proteins/*analysis
Proteomics/*instrumentation
Proteomics/*methods
Animals ; Gene Expression Profiling ; Humans ; Protein Binding ; Proteins/chemistry ; Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 89

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