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Tytuł:
Potentiometric Determination of Maprotiline Hydrochloride in Pharmaceutical and Biological Matrices Using a Novel Modified Carbon Paste Electrode.
Autorzy:
Radić J; Department of Environmental Chemistry, Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, 21000 Split, Croatia.
Perović D; Department of Environmental Chemistry, Faculty of Chemistry and Technology, University of Split, R. Boškovića 35, 21000 Split, Croatia.
Gričar E; Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.
Kolar M; Department of Chemistry and Biochemistry, Faculty of Chemistry and Chemical Technology, University of Ljubljana, Večna pot 113, 1000 Ljubljana, Slovenia.
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Źródło:
Sensors (Basel, Switzerland) [Sensors (Basel)] 2022 Nov 26; Vol. 22 (23). Date of Electronic Publication: 2022 Nov 26.
Typ publikacji:
Journal Article
MeSH Terms:
Carbon*/chemistry
Maprotiline*
Reproducibility of Results ; Potentiometry ; Pharmaceutical Preparations
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of the LC mobile phase in vacuum differential mobility spectrometry-mass spectrometry for the selective analysis of antidepressant drugs in human plasma.
Autorzy:
Girard MFC; Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva, 24 Quai Ernest Ansermet, CH-1211, Geneva 4, Switzerland.
Knight P; Shimadzu Research Laboratory, Wharfside, Trafford Wharf Road, Manchester, M17 1GP, UK.
Giles R; Shimadzu Research Laboratory, Wharfside, Trafford Wharf Road, Manchester, M17 1GP, UK.
Hopfgartner G; Life Sciences Mass Spectrometry, Department of Inorganic and Analytical Chemistry, University of Geneva, 24 Quai Ernest Ansermet, CH-1211, Geneva 4, Switzerland. .
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Źródło:
Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2022 Oct; Vol. 414 (24), pp. 7243-7252. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Imipramine*
Nortriptyline*
Acetonitriles ; Amitriptyline ; Antidepressive Agents ; Desipramine ; Humans ; Maprotiline ; Mass Spectrometry ; Methanol ; Reproducibility of Results ; Spectrum Analysis ; Vacuum ; Venlafaxine Hydrochloride
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Screen of FDA-approved drug library identifies maprotiline, an antibiofilm and antivirulence compound with QseC sensor-kinase dependent activity in Francisella novicida.
Autorzy:
Dean SN; a National Center for Biodefense and Infectious Diseases ; Manassas , VA , USA.
van Hoek ML
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Źródło:
Virulence [Virulence] 2015; Vol. 6 (5), pp. 487-503.
Typ publikacji:
Journal Article
MeSH Terms:
Biofilms/*drug effects
Francisella/*drug effects
Maprotiline/*chemistry
Maprotiline/*pharmacology
Protein Kinases/*metabolism
Tularemia/*drug therapy
Animals ; Biofilms/growth & development ; Disease Models, Animal ; Female ; Francisella/genetics ; Francisella/metabolism ; Francisella/pathogenicity ; Gene Expression Regulation, Bacterial ; Genomic Islands ; Histidine Kinase ; Larva/microbiology ; Maprotiline/isolation & purification ; Maprotiline/therapeutic use ; Mice ; Microbial Sensitivity Tests ; Moths/microbiology ; Protein Kinases/chemistry ; Tularemia/microbiology ; United States ; United States Food and Drug Administration ; Virulence/drug effects ; Virulence Factors/genetics ; Virulence Factors/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
A Multi-Species Phenotypic Screening Assay for Leishmaniasis Drug Discovery Shows That Active Compounds Display a High Degree of Species-Specificity.
Autorzy:
Alcântara LM; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP 13083-970, Brazil.; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-900, Brazil.
Ferreira TCS; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP 13083-970, Brazil.; Instituto Butantan, São Paulo, SP 05503-900, Brazil.
Fontana V; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP 13083-970, Brazil.
Chatelain E; Drugs for Neglected Diseases Initiative, 1211 Geneva, Switzerland.
Moraes CB; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP 13083-970, Brazil.; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-900, Brazil.
Freitas-Junior LH; Laboratório Nacional de Biociências (LNBio), Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP 13083-970, Brazil.; Departamento de Microbiologia, Instituto de Ciências Biomédicas, Universidade de São Paulo, São Paulo, SP 05508-900, Brazil.; Instituto Butantan, São Paulo, SP 05503-900, Brazil.
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2020 May 30; Vol. 25 (11). Date of Electronic Publication: 2020 May 30.
Typ publikacji:
Journal Article
MeSH Terms:
Leishmaniasis/*drug therapy
Animals ; Antiprotozoal Agents/therapeutic use ; Drug Evaluation, Preclinical ; Humans ; Leishmania/drug effects ; Leishmania/pathogenicity ; Leishmaniasis, Visceral/drug therapy ; Maprotiline/chemistry ; Mice ; Protriptyline/chemistry ; Species Specificity ; THP-1 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Effects of repeated maprotiline and fluoxetine treatment on gene expression of catecholamine synthesizing enzymes in adrenal medulla of unstressed and stressed rats.
Autorzy:
Spasojevic N; Institute of Nuclear Sciences Vinca, Laboratory of Molecular Biology and Endocrinology, 11000 Belgrade, Serbia.
Gavrilovic L
Dronjak S
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Źródło:
Autonomic & autacoid pharmacology [Auton Autacoid Pharmacol] 2010 Oct; Vol. 30 (4), pp. 213-7. Date of Electronic Publication: 2010 Jul 05.
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenal Medulla/*drug effects
Dopamine beta-Hydroxylase/*metabolism
Fluoxetine/*pharmacology
Gene Expression Regulation, Enzymologic/*drug effects
Maprotiline/*pharmacology
Stress, Physiological/*drug effects
Tyrosine 3-Monooxygenase/*metabolism
Adrenal Medulla/enzymology ; Adrenal Medulla/metabolism ; Adrenergic Uptake Inhibitors/pharmacology ; Adrenergic Uptake Inhibitors/therapeutic use ; Animals ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Dopamine beta-Hydroxylase/genetics ; Epinephrine/metabolism ; Fluoxetine/therapeutic use ; Male ; Maprotiline/therapeutic use ; Norepinephrine/metabolism ; Phenylethanolamine N-Methyltransferase/genetics ; Phenylethanolamine N-Methyltransferase/metabolism ; RNA, Messenger/metabolism ; Random Allocation ; Rats ; Rats, Wistar ; Selective Serotonin Reuptake Inhibitors/pharmacology ; Selective Serotonin Reuptake Inhibitors/therapeutic use ; Stress, Psychological/drug therapy ; Stress, Psychological/enzymology ; Stress, Psychological/metabolism ; Tyrosine 3-Monooxygenase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Antidepressant stimulation of CDP-diacylglycerol synthesis does not require monoamine reuptake inhibition.
Autorzy:
Aboukhatwa MA; Laboratory of Integrative Neuropharmacology, Department of Pharmaceutical Sciences, Thomas Jefferson University School of Pharmacy, Philadelphia, Pennsylvania, USA.
Undieh AS
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Źródło:
BMC neuroscience [BMC Neurosci] 2010 Jan 27; Vol. 11, pp. 10. Date of Electronic Publication: 2010 Jan 27.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Antidepressive Agents/*pharmacology
Biogenic Monoamines/*antagonists & inhibitors
Cytidine Diphosphate Diglycerides/*biosynthesis
Imipramine/*pharmacology
Maprotiline/*pharmacology
Paroxetine/*pharmacology
Animals ; Antidepressive Agents/administration & dosage ; Biogenic Monoamines/metabolism ; Cerebral Cortex/drug effects ; Cerebral Cortex/enzymology ; Cerebral Cortex/metabolism ; Cytidine Diphosphate Diglycerides/metabolism ; Diacylglycerol Cholinephosphotransferase/metabolism ; Dose-Response Relationship, Drug ; Hippocampus/drug effects ; Hippocampus/enzymology ; Hippocampus/metabolism ; Imipramine/administration & dosage ; Male ; Maprotiline/administration & dosage ; Mice ; Mice, Inbred C57BL ; PC12 Cells ; Paroxetine/administration & dosage ; Rats ; Rats, Sprague-Dawley ; Serotonin/deficiency ; Serotonin/metabolism ; Serotonin Plasma Membrane Transport Proteins/deficiency ; Serotonin Plasma Membrane Transport Proteins/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Visual perseveration: a new side effect of maprotiline.
Autorzy:
Hori H; Department of Psychiatry, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.
Terao T
Nakamura J
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Źródło:
Acta psychiatrica Scandinavica [Acta Psychiatr Scand] 2000 Jun; Vol. 101 (6), pp. 476-7.
Typ publikacji:
Case Reports; Journal Article
MeSH Terms:
Visual Perception*
Antidepressive Agents, Second-Generation/*adverse effects
Maprotiline/*adverse effects
Perceptual Disorders/*chemically induced
Antidepressive Agents, Second-Generation/pharmacology ; Brain/drug effects ; Brain/physiopathology ; Depression/drug therapy ; Dose-Response Relationship, Drug ; Drug Therapy, Combination ; Electroencephalography ; Humans ; Male ; Maprotiline/pharmacology ; Middle Aged
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer.
Autorzy:
Byun S; Division of Bioengineering, Incheon National University, Incheon 22012, Korea. .
Lee E; Traditional Alcoholic Beverage Research Team, Korea Food Research Institute, Seongnam 13539, Korea. .
Lee KW; Advanced Institutes of Convergence Technology, Seoul National University, Suwon 16495, Korea. .; Research Institute of Agriculture and Life Sciences, Seoul National University, Seoul 08826, Korea. .
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2017 Sep 12; Vol. 18 (9). Date of Electronic Publication: 2017 Sep 12.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autophagy/*immunology
Autophagy/*physiology
Immune System Diseases/*immunology
Infections/*immunology
Neoplasms/*immunology
Adaptive Immunity/immunology ; Animals ; Autoimmune Diseases/immunology ; Autophagy/drug effects ; Benzylisoquinolines/pharmacology ; Cholecalciferol/pharmacology ; Humans ; Immunity, Innate/immunology ; Indoles ; Isoquinolines/pharmacology ; Lysosomes/metabolism ; Maprotiline/pharmacology ; Metformin/pharmacology ; Phenols/pharmacology ; Pyrroles/pharmacology ; Resveratrol ; Sirolimus/pharmacology ; Spermidine/pharmacology ; Stilbenes/pharmacology ; Tetrahydroisoquinolines/pharmacology ; Trehalose/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Exploring the Inhibitory Mechanism of Approved Selective Norepinephrine Reuptake Inhibitors and Reboxetine Enantiomers by Molecular Dynamics Study.
Autorzy:
Zheng G; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Xue W; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Wang P; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Yang F; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Li B; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Li X; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Li Y; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
Yao X; State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, China.
Zhu F; Innovative Drug Research and Bioinformatics Group, Innovative Drug Research Centre and School of Pharmaceutical Sciences, Chongqing University, Chongqing 401331, China.
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Źródło:
Scientific reports [Sci Rep] 2016 May 27; Vol. 6, pp. 26883. Date of Electronic Publication: 2016 May 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Molecular Dynamics Simulation*
Antipsychotic Agents/*chemistry
Morpholines/*chemistry
Neurotransmitter Uptake Inhibitors/*chemistry
Norepinephrine/*chemistry
Norepinephrine Plasma Membrane Transport Proteins/*chemistry
Amino Acid Motifs ; Antipsychotic Agents/metabolism ; Atomoxetine Hydrochloride/chemistry ; Atomoxetine Hydrochloride/metabolism ; Binding Sites ; Humans ; Maprotiline/chemistry ; Maprotiline/metabolism ; Molecular Docking Simulation ; Morpholines/metabolism ; Neurotransmitter Uptake Inhibitors/metabolism ; Norepinephrine/metabolism ; Norepinephrine Plasma Membrane Transport Proteins/antagonists & inhibitors ; Norepinephrine Plasma Membrane Transport Proteins/metabolism ; Protein Binding ; Protein Conformation, alpha-Helical ; Protein Conformation, beta-Strand ; Protein Interaction Domains and Motifs ; Reboxetine ; Stereoisomerism ; Structural Homology, Protein ; Thermodynamics ; Viloxazine/chemistry ; Viloxazine/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Synthesis of Chlorinated Tetracyclic Compounds and Testing for Their Potential Antidepressant Effect in Mice.
Autorzy:
Karama U; Chemistry Department, College of Science, King Saud University, P. O. Box 2455 Riyadh 11451, Saudi Arabia. .
Sultan MA; Chemistry Department, College of Science, King Saud University, P. O. Box 2455 Riyadh 11451, Saudi Arabia. .
Almansour AI; Chemistry Department, College of Science, King Saud University, P. O. Box 2455 Riyadh 11451, Saudi Arabia. .
El-Taher KE; Department of Pharmacology, College of Pharmacy, King Saud University, P. O. Box 2457, Riyadh 11451, Saudi Arabia. .
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Źródło:
Molecules (Basel, Switzerland) [Molecules] 2016 Jan 05; Vol. 21 (1), pp. 61. Date of Electronic Publication: 2016 Jan 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anthracenes/*chemical synthesis
Anti-Anxiety Agents/*chemical synthesis
Antidepressive Agents/*chemical synthesis
Hydrocarbons, Chlorinated/*chemical synthesis
Animals ; Anthracenes/chemistry ; Anthracenes/pharmacology ; Anti-Anxiety Agents/chemistry ; Anti-Anxiety Agents/pharmacology ; Antidepressive Agents/chemistry ; Antidepressive Agents/pharmacology ; Hydrocarbons, Chlorinated/chemistry ; Hydrocarbons, Chlorinated/pharmacology ; Immobility Response, Tonic/drug effects ; Maprotiline/chemistry ; Maprotiline/pharmacology ; Mice ; Molecular Structure ; Swimming
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Teaching old drugs new tricks: Addressing resistance in Francisella.
Autorzy:
Feldmann EA; a Department of Molecular and Structural Biochemistry; North Carolina State University ; Raleigh , NC , USA.
Cavanagh J
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Źródło:
Virulence [Virulence] 2015; Vol. 6 (5), pp. 414-6.
Typ publikacji:
Editorial; Comment
MeSH Terms:
Biofilms/*drug effects
Francisella/*drug effects
Maprotiline/*chemistry
Maprotiline/*pharmacology
Protein Kinases/*metabolism
Tularemia/*drug therapy
Animals ; Female
Opinia redakcyjna
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Amelioration of the reduced antinociceptive effect of morphine in the unpredictable chronic mild stress model mice by noradrenalin but not serotonin reuptake inhibitors.
Autorzy:
Ide S; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. .; Addictive Substance Project, Tokyo Metropolitan Institute of Medical Science, Tokyo, Japan. .
Satoyoshi H; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. .
Minami M; Department of Pharmacology, Graduate School of Pharmaceutical Sciences, Hokkaido University, Sapporo, Japan. .
Satoh M; Graduate School of Pharmaceutical Sciences, Kyoto University, Kyoto, Japan. .
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Źródło:
Molecular pain [Mol Pain] 2015 Aug 11; Vol. 11, pp. 47. Date of Electronic Publication: 2015 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Analgesics/*pharmacology
Morphine/*pharmacology
Norepinephrine/*pharmacology
Selective Serotonin Reuptake Inhibitors/*pharmacology
Stress, Physiological/*drug effects
Animals ; Chronic Disease ; Citalopram/pharmacology ; Disease Models, Animal ; Male ; Maprotiline/pharmacology ; Mice, Inbred BALB C ; Temperature ; Tramadol/pharmacology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Maprotiline ameliorates isoflurane-induced microglial activation via regulating triggering receptor expressed in myeloid cells 2 (TREM2)
Autorzy:
Rui Hu
Yongguan He
Zhigang Chen
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Temat:
isoflurane
maprotiline
microglial activation
oxidative stress
inflammation
trem2
Biotechnology
TP248.13-248.65
Źródło:
Bioengineered, Vol 12, Iss 2, Pp 12332-12344 (2021)
Opis pliku:
electronic resource
Relacje:
https://doaj.org/toc/2165-5979; https://doaj.org/toc/2165-5987
Dostęp URL:
https://doaj.org/article/bfc4dc58cf6442f598657f95565d7eb4  Link otwiera się w nowym oknie
Czasopismo naukowe
Szczegóły
Tytuł:
Antidepressants that inhibit both serotonin and norepinephrine reuptake impair long-term potentiation in hippocampus.
Autorzy:
Cooke JD; Department of Pharmacology, Physiology and Toxicology, Joan C. Edwards School of Medicine, Marshall University, Robert C. Byrd Biotechnology Science Center, One John Marshall Drive, Huntington, WV, 25755, USA.
Cavender HM
Lima HK
Grover LM
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Źródło:
Psychopharmacology [Psychopharmacology (Berl)] 2014 Dec; Vol. 231 (23), pp. 4429-41. Date of Electronic Publication: 2014 Apr 30.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Adrenergic Uptake Inhibitors/*pharmacology
Hippocampus/*drug effects
Long-Term Potentiation/*drug effects
Selective Serotonin Reuptake Inhibitors/*pharmacology
Synaptic Transmission/*drug effects
Animals ; Antidepressive Agents/pharmacology ; Brain-Derived Neurotrophic Factor/metabolism ; Cyclohexanols/pharmacology ; Fluoxetine/pharmacology ; Hippocampus/metabolism ; Imipramine/pharmacology ; Male ; Maprotiline/pharmacology ; Norepinephrine/metabolism ; Serotonin/metabolism ; Venlafaxine Hydrochloride
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Amitriptyline, clomipramine, and maprotiline attenuate the inflammatory response by inhibiting neutrophil migration and mast cell degranulation.
Autorzy:
Gurgel JA; Department of Physiology and Pharmacology, School of Medicine, Universidade Federal do Ceará (UFC), FortalezaCE, Brazil.
Lima-Júnior RC; Department of Physiology and Pharmacology, School of Medicine, Universidade Federal do Ceará (UFC), FortalezaCE, Brazil.
Rabelo CO; Department of Physiology and Pharmacology, School of Medicine, Universidade Federal do Ceará (UFC), FortalezaCE, Brazil.
Pessoa BB; Department of Physiology and Pharmacology, School of Medicine, Universidade Federal do Ceará (UFC), FortalezaCE, Brazil.
Brito GA; Department of Morphology, School of Medicine, UFC, FortalezaCE, Brazil.
Ribeiro RA; Department of Physiology and Pharmacology, School of Medicine, Universidade Federal do Ceará (UFC), FortalezaCE, Brazil.
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Źródło:
Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) [Braz J Psychiatry] 2013 Oct-Dec; Vol. 35 (4), pp. 387-92. Date of Electronic Publication: 2013 Dec 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amitriptyline/*pharmacology
Anti-Inflammatory Agents/*pharmacology
Cell Degranulation/*drug effects
Clomipramine/*pharmacology
Maprotiline/*pharmacology
Mast Cells/*drug effects
Neutrophil Infiltration/*drug effects
Animals ; Carrageenan/adverse effects ; Cell Movement/drug effects ; Disease Models, Animal ; Edema/chemically induced ; Male ; Mast Cells/physiology ; Rats ; Rats, Wistar
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Wyświetlanie 1-20 z 303

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