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Tytuł :
MCM10 compensates for Myc-induced DNA replication stress in breast cancer stem-like cells.
Autorzy :
Murayama T; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Takeuchi Y; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Yamawaki K; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.; Department of Obstetrics and Gynecology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Natsume T; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima City, Japan.; Department of Genetics, SOKENDAI, Mishima City, Japan.
Li M; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Marcela RN; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Nishimura T; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
Kogure Y; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Science, The University of Tokyo, Kashiwa City, Japan.
Nakata A; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.; Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Tominaga K; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.
Sasahara A; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Department of Breast & Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Yano M; Department of Surgery, Minamimachida Hospital, Machida City, Japan.
Ishikawa S; Department of Gastroenterological Surgery, Kanazawa University, Kanazawa City, Japan.
Ohta T; Department of Gastroenterological Surgery, Kanazawa University, Kanazawa City, Japan.
Ikeda K; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Horie-Inoue K; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Inoue S; Division of Gene Regulation and Signal Transduction, Research Center for Genomic Medicine, Saitama Medical University, Hidaka City, Japan.
Seki M; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Suzuki Y; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Sugano S; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa City, Japan.
Enomoto T; Department of Obstetrics and Gynecology, Graduate School of Medical and Dental Sciences, Niigata University, Niigata, Japan.
Tanabe M; Department of Breast & Endocrine Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Japan.
Tada KI; Department of Pediatrics, Faculdade de Medicina, Universidade de São Paulo, São Paulo, Brazil.
Kanemaki MT; Department of Chromosome Science, National Institute of Genetics, Research Organization of Information and Systems (ROIS), Mishima City, Japan.; Department of Genetics, SOKENDAI, Mishima City, Japan.
Okamoto K; Division of Cancer Differentiation, National Cancer Center Research Institute, Chuo-ku, Japan.
Tojo A; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.
Gotoh N; Division of Molecular Therapy, Institute of Medical Science, The University of Tokyo, Minato-ku, Japan.; Division of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa City, Japan.
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Źródło :
Cancer science [Cancer Sci] 2021 Mar; Vol. 112 (3), pp. 1209-1224. Date of Electronic Publication: 2021 Jan 22.
Typ publikacji :
Journal Article
MeSH Terms :
Breast Neoplasms/*genetics
Minichromosome Maintenance Proteins/*metabolism
Neoplasm Recurrence, Local/*genetics
Neoplastic Stem Cells/*pathology
Proto-Oncogene Proteins c-myc/*metabolism
Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Breast/pathology ; Breast Neoplasms/drug therapy ; Breast Neoplasms/pathology ; DNA Damage/drug effects ; DNA Replication/drug effects ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Female ; Humans ; Minichromosome Maintenance Proteins/genetics ; Neoplasm Recurrence, Local/pathology ; Neoplasm Recurrence, Local/prevention & control ; Neoplastic Stem Cells/drug effects ; Primary Cell Culture ; Proto-Oncogene Proteins c-myc/antagonists & inhibitors ; Spheroids, Cellular ; Tumor Cells, Cultured ; Up-Regulation
Czasopismo naukowe
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