Contribution of animal models to the mechanistic understanding of Alternative Pathway and Amplification Loop (AP/AL)-driven Complement-mediated Diseases.
Autorzy:
Gibson BG; Complement Therapeutics Research Group and Newcastle University Translational and Clinical Research Institute, Faculty of Medical Science, Newcastle-upon-Tyne, UK.; National Renal Complement Therapeutics Centre, aHUS Service, Newcastle upon Tyne, UK. Cox TE; Complement Therapeutics Research Group and Newcastle University Translational and Clinical Research Institute, Faculty of Medical Science, Newcastle-upon-Tyne, UK.; National Renal Complement Therapeutics Centre, aHUS Service, Newcastle upon Tyne, UK. MarchbankKJ; Complement Therapeutics Research Group and Newcastle University Translational and Clinical Research Institute, Faculty of Medical Science, Newcastle-upon-Tyne, UK.; National Renal Complement Therapeutics Centre, aHUS Service, Newcastle upon Tyne, UK.
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Źródło:
Immunological reviews [Immunol Rev] 2023 Jan; Vol. 313 (1), pp. 194-216. Date of Electronic Publication: 2022 Oct 06.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
Determining the Potential of DNA Damage Response (DDR) Inhibitors in Cervical Cancer Therapy.
Autorzy:
Saha S; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. Rundle S; The Northern Gynaecological Oncology Centre (NGOC), Queen Elizabeth Hospital, Gateshead NE9 6SX, UK. Kotsopoulos IC; University College London Hospitals NHS Foundation Trust, 250 Euston Rd, London NW1 2PG, UK. Begbie J; Addenbrooke's Hospital, Cambridge CB2 0QQ, UK. Howarth R; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK. Pappworth IY; Translational and Clinical Research Institute, National Renal Complement Therapeutics Centre, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Mukhopadhyay A; Kolkata Gynecological Oncology Trials and Translational Research Group, Chittaranjan National Cancer Institute, Kolkata 700026, India.; Department of Gynaecological Oncology, James Cook University Hospital, Middlesbrough TS4 3BW, UK.; Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Kucukmetin A; The Northern Gynaecological Oncology Centre (NGOC), Queen Elizabeth Hospital, Gateshead NE9 6SX, UK.; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. MarchbankKJ; Translational and Clinical Research Institute, National Renal Complement Therapeutics Centre, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Curtin N; Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, UK.
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Źródło:
Cancers [Cancers (Basel)] 2022 Sep 01; Vol. 14 (17). Date of Electronic Publication: 2022 Sep 01.
Ensilicated tetanus antigen retains immunogenicity: in vivo study and time-resolved SAXS characterization.
Autorzy:
Doekhie A; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. Dattani R; European Synchrotron Research Facility, ESRF, 71 avenue des Martyrs, CS 40220, 38043, Grenoble, Cedex 9, France. Chen YC; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom.; College of Pharmacy, Purdu Univeristy Heine Pharmacy Building, West Lafayette, IN, 47907-2091, United States. Yang Y; Transnational and Clinical Research Institute, Newcastle University, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom.; Department of Biochemistry, University of Cambridge, CB2 0QR, Cambridge, UK. Smith A; Diamond Light Source, Diamond Light Source Ltd, Harwell Campus, Didcot, OX11 0DE, United Kingdom. Silve AP; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. Koumanov F; Department for Health, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. Wells SA; Department of Chemical Engineering, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. Edler KJ; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. MarchbankKJ; Transnational and Clinical Research Institute, Newcastle University, Medical School, Newcastle upon Tyne, NE2 4HH, United Kingdom. Elsen JMHVD; Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. Sartbaeva A; Department of Chemistry, University of Bath, Claverton Down, Bath, BA2 7AY, United Kingdom. .
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Źródło:
Scientific reports [Sci Rep] 2020 Jun 08; Vol. 10 (1), pp. 9243. Date of Electronic Publication: 2020 Jun 08.
Thermal stability, storage and release of proteins with tailored fit in silica.
Autorzy:
Chen YC; Department of Chemistry, Claverton Down, Bath, BA2 7AY, UK. Smith T; Centre for Sustainable Chemical Technologies, Department of Biology and Biochemistry, Claverton Down, Bath, BA2 7AY, UK. Hicks RH; Centre for Sustainable Chemical Technologies, Department of Biology and Biochemistry, Claverton Down, Bath, BA2 7AY, UK. Doekhie A; Department of Chemistry, Claverton Down, Bath, BA2 7AY, UK. Koumanov F; Department of Biology and Biochemistry, Claverton Down, Bath, BA2 7AY, UK. Wells SA; Department of Chemical Engineering, University of Bath, Bath, BA2 7AY, UK. Edler KJ; Department of Chemistry, Claverton Down, Bath, BA2 7AY, UK. van den Elsen J; Department of Biology and Biochemistry, Claverton Down, Bath, BA2 7AY, UK. Holman GD; Department of Biology and Biochemistry, Claverton Down, Bath, BA2 7AY, UK. MarchbankKJ; The Medical School, Framlington Place, Newcastle upon Tyne, NE2 4HH, UK. Sartbaeva A; Department of Chemistry, Claverton Down, Bath, BA2 7AY, UK.
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Źródło:
Scientific reports [Sci Rep] 2017 Apr 24; Vol. 7, pp. 46568. Date of Electronic Publication: 2017 Apr 24.
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