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Tytuł :
Study of the antitumour effects and the modulation of immune response by histamine in breast cancer.
Autorzy :
Nicoud MB; Laboratory of Tumour Biology and Inflammation, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.; Laboratory of Radioisotopes, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina.
Sterle HA; Neuroimmunomodulation and Molecular Oncology Division, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Massari NA; Immunology Department, School of Natural Sciences, National University of Patagonia San Juan Bosco, Chubut, Argentina.
Táquez Delgado MA; Laboratory of Tumour Biology and Inflammation, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Formoso K; Pharmacology and Function of Ionic Channels Laboratory, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Herrero Ducloux MV; Pathology Department, School of Natural Sciences, National University of Patagonia San Juan Bosco, Chubut, Argentina.
Martinel Lamas D; Laboratory of Tumour Biology and Inflammation, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Cremaschi GA; Neuroimmunomodulation and Molecular Oncology Division, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina.
Medina VA; Laboratory of Tumour Biology and Inflammation, Institute for Biomedical Research (BIOMED), School of Medical Sciences, Pontifical Catholic University of Argentina (UCA), and the National Scientific and Technical Research Council (CONICET), Buenos Aires, Argentina. .; Laboratory of Radioisotopes, School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina. .
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Źródło :
British journal of cancer [Br J Cancer] 2020 Feb; Vol. 122 (3), pp. 348-360. Date of Electronic Publication: 2019 Nov 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Cell Proliferation/*drug effects
Histamine Agonists/*pharmacology
Histamine Antagonists/*pharmacology
Histidine Decarboxylase/*metabolism
Receptors, Histamine H4/*genetics
Receptors, Histamine H4/*metabolism
Triple Negative Breast Neoplasms/*metabolism
Animals ; Breast Neoplasms/metabolism ; Breast Neoplasms/mortality ; Cell Line, Tumor ; Cell Survival/drug effects ; Databases, Factual ; Female ; Histamine/pharmacology ; Humans ; Indoles/pharmacology ; Lymphocytes, Tumor-Infiltrating/drug effects ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Oximes/pharmacology ; Piperazines/pharmacology ; Prognosis ; Triple Negative Breast Neoplasms/mortality ; Tumor Burden ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
The synergistic effect of DZ‑NEP, panobinostat and temozolomide reduces clonogenicity and induces apoptosis in glioblastoma cells.
Autorzy :
De La Rosa J; Department of Biochemistry and Genetics, University of Navarra School of Sciences, 31008 Pamplona, Spain.
Urdiciain A; Department of Biochemistry and Genetics, University of Navarra School of Sciences, 31008 Pamplona, Spain.
Zazpe I; Department of Neurosurgery, Hospital Complex of Navarra, 31008 Pamplona, Spain.
Zelaya MV; Department of Pathology, Hospital Complex of Navarra, 31008 Pamplona, Spain.
Meléndez B; Molecular Pathology Research Unit, Department of Pathology, Virgen de la Salud Hospital, 45005 Toledo, Spain.
Rey JA; IdiPaz Research Unit, La Paz University Hospital, 28046 Madrid, Spain.
Idoate MA; Department of Pathology, University of Navarra Clinic, 31008 Pamplona, Spain.
Castresana JS; Department of Biochemistry and Genetics, University of Navarra School of Sciences, 31008 Pamplona, Spain.
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Źródło :
International journal of oncology [Int J Oncol] 2020 Jan; Vol. 56 (1), pp. 283-300. Date of Electronic Publication: 2019 Oct 30.
Typ publikacji :
Journal Article
MeSH Terms :
Apoptosis*
Drug Resistance, Neoplasm*
Drug Synergism*
Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Biomarkers, Tumor/*metabolism
Glioblastoma/*pathology
Adenosine/administration & dosage ; Adenosine/analogs & derivatives ; Cell Proliferation ; Gene Expression Regulation, Neoplastic ; Glioblastoma/drug therapy ; Glioblastoma/metabolism ; Humans ; Panobinostat/administration & dosage ; Temozolomide/administration & dosage ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
Interaction of Zn with Losartan. Activation of Intrinsic Apoptotic Signaling Pathway in Lung Cancer Cells and Effects on Alkaline and Acid Phosphatases.
Autorzy :
Martínez VR; Centro de Química Inorgánica (CEQUINOR-CONICET-CICPBA-UNLP), 120 N° 1465, La Plata, Argentina.
Aguirre MV; Laboratorio de Investigaciones Bioquímicas, Facultad de Medicina, UNNE, Moreno, 1240, Corrientes, Argentina.
Todaro JS; Laboratorio de Investigaciones Bioquímicas, Facultad de Medicina, UNNE, Moreno, 1240, Corrientes, Argentina.
Piro OE; Departamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata y IFLP (CONICET, CCT La Plata), C.C. 67, 1900, La Plata, Argentina.
Echeverría GA; Departamento de Física, Facultad de Ciencias Exactas, Universidad Nacional de La Plata y IFLP (CONICET, CCT La Plata), C.C. 67, 1900, La Plata, Argentina.
Naso LG; Centro de Química Inorgánica (CEQUINOR-CONICET-CICPBA-UNLP), 120 N° 1465, La Plata, Argentina.
Ferrer EG; Centro de Química Inorgánica (CEQUINOR-CONICET-CICPBA-UNLP), 120 N° 1465, La Plata, Argentina.
Williams PAM; Centro de Química Inorgánica (CEQUINOR-CONICET-CICPBA-UNLP), 120 N° 1465, La Plata, Argentina. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2018 Dec; Vol. 186 (2), pp. 413-429. Date of Electronic Publication: 2018 Apr 12.
Typ publikacji :
Journal Article
MeSH Terms :
Acid Phosphatase/*metabolism
Alkaline Phosphatase/*metabolism
Apoptosis/*drug effects
Coordination Complexes/*pharmacology
Losartan/*pharmacology
Zinc/*pharmacology
A549 Cells ; Angiotensin II Type 1 Receptor Blockers/chemistry ; Angiotensin II Type 1 Receptor Blockers/pharmacology ; Caspase 3/metabolism ; Coordination Complexes/chemistry ; Glutathione/metabolism ; Humans ; Losartan/chemistry ; Lung Neoplasms/metabolism ; Lung Neoplasms/pathology ; Reactive Oxygen Species/metabolism ; Signal Transduction/drug effects ; Zinc/chemistry ; bcl-2-Associated X Protein/metabolism ; bcl-X Protein/metabolism
Czasopismo naukowe
Tytuł :
Effects of antioxidants on apoptosis induced by dasatinib and nilotinib in K562 cells.
Autorzy :
Damiano S; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Montagnaro S; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Puzio MV; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Severino L; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Pagnini U; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Barbarino M; Sbarro Institute for Cancer Research and Molecular Medicine, Department of Biology, Center of Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.; Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
Cesari D; Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
Giordano A; Sbarro Institute for Cancer Research and Molecular Medicine, Department of Biology, Center of Biotechnology, College of Science and Technology, Temple University, Philadelphia, Pennsylvania.; Department of Medicine, Surgery and Neuroscience, University of Siena, Siena, Italy.
Florio S; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
Ciarcia R; Department of Veterinary Medicine and Animal Productions, University of Naples Federico II, Naples, Italy.
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Źródło :
Journal of cellular biochemistry [J Cell Biochem] 2018 Jun; Vol. 119 (6), pp. 4845-4854. Date of Electronic Publication: 2018 Mar 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antioxidants/*pharmacology
Apoptosis/*drug effects
Dasatinib/*pharmacology
Drug Resistance, Neoplasm/*drug effects
Reactive Oxygen Species/*metabolism
Tocopherols/*pharmacology
Humans ; K562 Cells
Czasopismo naukowe
Tytuł :
Lipophilic ester and amide derivatives of rosmarinic acid protect cells against H 2 O 2 -induced DNA damage and apoptosis: The potential role of intracellular accumulation and labile iron chelation.
Autorzy :
Gerogianni PS; Laboratory of Biological Chemistry, School of Health Sciences, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece.
Chatziathanasiadou MV; Laboratory of Organic Chemistry and Biochemistry, School of Natural Sciences, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Diamantis DA; Laboratory of Organic Chemistry and Biochemistry, School of Natural Sciences, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Tzakos AG; Laboratory of Organic Chemistry and Biochemistry, School of Natural Sciences, Department of Chemistry, University of Ioannina, 45110 Ioannina, Greece.
Galaris D; Laboratory of Biological Chemistry, School of Health Sciences, Faculty of Medicine, University of Ioannina, 45110 Ioannina, Greece. Electronic address: .
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Źródło :
Redox biology [Redox Biol] 2018 May; Vol. 15, pp. 548-556. Date of Electronic Publication: 2018 Feb 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Cinnamates/*pharmacology
DNA Damage/*drug effects
Depsides/*pharmacology
Oxidative Stress/*drug effects
Amides/chemistry ; Amides/pharmacology ; Cinnamates/chemistry ; Cinnamates/metabolism ; Cytoplasm/drug effects ; Cytoplasm/metabolism ; Depsides/chemistry ; Depsides/metabolism ; Esters/chemistry ; Esters/pharmacology ; Humans ; Hydrogen Peroxide/toxicity ; Iron/chemistry ; Iron Chelating Agents/chemistry ; Jurkat Cells ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Assessment of Radiobiological α/β Ratio in Lung Cancer and Fibroblast Cell Lines Using Viability Assays.
Autorzy :
Karagounis IV; Department of Radiotherapy/Oncology, Democritus University of Thrace, Alexandroupolis, Greece.
Skourti EK; Department of Radiotherapy/Oncology, Democritus University of Thrace, Alexandroupolis, Greece.
Liousia MV; Department of Radiotherapy/Oncology, Democritus University of Thrace, Alexandroupolis, Greece.
Koukourakis MI; Department of Radiotherapy/Oncology, Democritus University of Thrace, Alexandroupolis, Greece .
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Źródło :
In vivo (Athens, Greece) [In Vivo] 2017 Mar-Apr; Vol. 31 (2), pp. 175-179.
Typ publikacji :
Journal Article
MeSH Terms :
Dose-Response Relationship, Radiation*
Apoptosis/*radiation effects
Cell Proliferation/*radiation effects
Fibroblasts/*radiation effects
A549 Cells ; Cell Line ; Cell Line, Tumor ; Cell Survival/radiation effects ; Dose Fractionation, Radiation ; Fibroblasts/cytology ; Humans ; Lung Neoplasms/pathology ; Lung Neoplasms/radiotherapy ; Radiotherapy/methods
Czasopismo naukowe
Tytuł :
Fever-range hyperthermia improves the anti-apoptotic effect induced by low pH on human neutrophils promoting a proangiogenic profile.
Autorzy :
Díaz FE; Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Dantas E; Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Cabrera M; Instituto de Investigaciones Farmacológicas (ININFA), CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Benítez CA; Instituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Delpino MV; Instituto de Inmunología, Genética y Metabolismo (INIGEM), CONICET, Facultad de Farmacia y Bioquímica, Universidad de Buenos Aires, Buenos Aires, Argentina.
Duette G; Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Rubione J; Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Sanjuan N; Instituto de Investigaciones en Microbiología y Parasitología Médica (IMPAM), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
Trevani AS; Instituto de Medicina Experimental (IMEX), CONICET, Academia Nacional de Medicina, Buenos Aires, Argentina.
Geffner J; Instituto de Investigaciones Biomédicas en Retrovirus y SIDA (INBIRS), CONICET, Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina.
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Źródło :
Cell death & disease [Cell Death Dis] 2016 Oct 27; Vol. 7 (10), pp. e2437. Date of Electronic Publication: 2016 Oct 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Hyperthermia, Induced*
Neovascularization, Physiologic*
Fever/*pathology
Neutrophils/*pathology
Cell Proliferation ; Humans ; Hydrogen-Ion Concentration ; Phenotype ; T-Lymphocytes/metabolism
Czasopismo naukowe
Tytuł :
Chronic hepatitis C virus infection: Serum biomarkers in predicting liver damage.
Autorzy :
Valva P; Pamela Valva, Daniela A Ríos, Elena De Matteo, María V Preciado, Laboratory of Molecular Biology, Pathology Division, Hospital de Niños Ricardo Gutiérrez, Buenos Aires C1425EFD, Argentina.
Ríos DA; Pamela Valva, Daniela A Ríos, Elena De Matteo, María V Preciado, Laboratory of Molecular Biology, Pathology Division, Hospital de Niños Ricardo Gutiérrez, Buenos Aires C1425EFD, Argentina.
De Matteo E; Pamela Valva, Daniela A Ríos, Elena De Matteo, María V Preciado, Laboratory of Molecular Biology, Pathology Division, Hospital de Niños Ricardo Gutiérrez, Buenos Aires C1425EFD, Argentina.
Preciado MV; Pamela Valva, Daniela A Ríos, Elena De Matteo, María V Preciado, Laboratory of Molecular Biology, Pathology Division, Hospital de Niños Ricardo Gutiérrez, Buenos Aires C1425EFD, Argentina.
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Źródło :
World journal of gastroenterology [World J Gastroenterol] 2016 Jan 28; Vol. 22 (4), pp. 1367-81.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Apoptosis*
Biomarkers/*blood
Hepatitis C, Chronic/*blood
Liver/*metabolism
Age Factors ; Biopsy ; Hepatitis C, Chronic/pathology ; Hepatitis C, Chronic/virology ; Humans ; Liver/pathology ; Liver/virology ; Liver Function Tests ; Predictive Value of Tests ; Prognosis ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Amelioration of lipopolysaccharide-induced acute kidney injury by erythropoietin: involvement of mitochondria-regulated apoptosis.
Autorzy :
Stoyanoff TR; Department of Biochemistry, School of Medicine, National Northeast University, Moreno 1240 (3400), Corrientes, Argentina; CONICET-SEGCyT, National Northeast University, Argentina.
Todaro JS; Department of Biochemistry, School of Medicine, National Northeast University, Moreno 1240 (3400), Corrientes, Argentina; SEGCyT, National Northeast University, Argentina.
Aguirre MV; Department of Biochemistry, School of Medicine, National Northeast University, Moreno 1240 (3400), Corrientes, Argentina. Electronic address: .
Zimmermann MC; Department of Biochemistry, School of Medicine, National Northeast University, Moreno 1240 (3400), Corrientes, Argentina; CONICET, Argentina.
Brandan NC; Department of Biochemistry, School of Medicine, National Northeast University, Moreno 1240 (3400), Corrientes, Argentina; CONICET, Argentina.
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Źródło :
Toxicology [Toxicology] 2014 Apr 06; Vol. 318, pp. 13-21. Date of Electronic Publication: 2014 Feb 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Acute Kidney Injury/*drug therapy
Acute Kidney Injury/*physiopathology
Apoptosis/*physiology
Cryoprotective Agents/*pharmacology
Erythropoietin/*pharmacology
Mitochondria/*metabolism
Receptors, Erythropoietin/*metabolism
Acute Kidney Injury/chemically induced ; Animals ; Apoptosis/drug effects ; Disease Models, Animal ; Humans ; Kidney/metabolism ; Lipopolysaccharides ; Male ; Mice ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
Extremely low-frequency electromagnetic fields enhance the survival of newborn neurons in the mouse hippocampus.
Autorzy :
Podda MV; Institute of Human Physiology, Medical School, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168, Rome, Italy.
Leone L
Barbati SA
Mastrodonato A
Li Puma DD
Piacentini R
Grassi C
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Źródło :
The European journal of neuroscience [Eur J Neurosci] 2014 Mar; Vol. 39 (6), pp. 893-903. Date of Electronic Publication: 2013 Dec 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Electromagnetic Fields*
Hippocampus/*radiation effects
Neurons/*radiation effects
Animals ; Cell Survival/radiation effects ; Hippocampus/cytology ; Hippocampus/growth & development ; Hippocampus/physiology ; Male ; Maze Learning ; Memory ; Mice ; Mice, Inbred C57BL ; Neurogenesis ; Neurons/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; bcl-2-Associated X Protein/genetics ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Short-term episodes of hypoxia induce posthypoxic hyperexcitability and selective death of GABAergic hippocampal neurons.
Autorzy :
Turovsky EA; Institute of Cell Biophysics, Russian Academy of Sciences, Pushchino, Russia.
Turovskaya MV
Kononov AV
Zinchenko VP
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Źródło :
Experimental neurology [Exp Neurol] 2013 Dec; Vol. 250, pp. 1-7. Date of Electronic Publication: 2013 Sep 13.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ischemic Preconditioning*
Apoptosis/*physiology
GABAergic Neurons/*pathology
Hippocampus/*pathology
Hypoxia/*metabolism
Interleukin-10/*metabolism
Animals ; Apoptosis/drug effects ; Calcium/metabolism ; Cell Hypoxia/drug effects ; Cell Hypoxia/physiology ; Cell Survival/drug effects ; Cell Survival/physiology ; Excitatory Amino Acids/pharmacology ; GABAergic Neurons/metabolism ; Hippocampus/blood supply ; Hippocampus/metabolism ; Immunohistochemistry ; N-Methylaspartate/pharmacology ; Rats ; Signal Transduction/drug effects ; Signal Transduction/physiology
Czasopismo naukowe
Tytuł :
Apoptotic activity of the marine diatom Cocconeis scutellum and eicosapentaenoic acid in BT20 cells.
Autorzy :
Nappo M; Department of Natural Products, Plant Biology and Soil Science, Faculty of Pharmacy, University of Barcelona, Spain. />Berkov S
Massucco C
Di Maria V
Bastida J
Codina C
Avila C
Messina P
Zupo V
Zupo S
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Źródło :
Pharmaceutical biology [Pharm Biol] 2012 Apr; Vol. 50 (4), pp. 529-35. Date of Electronic Publication: 2011 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Agents/*pharmacology
Apoptosis/*drug effects
Breast Neoplasms/*pathology
Diatoms/*chemistry
Eicosapentaenoic Acid/*pharmacology
Antineoplastic Agents/chemistry ; Antineoplastic Agents/isolation & purification ; Blotting, Western ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Line, Tumor ; Cell Survival/drug effects ; Chemical Fractionation ; Dose-Response Relationship, Drug ; Eicosapentaenoic Acid/chemistry ; Eicosapentaenoic Acid/isolation & purification ; Enzyme Activation ; Female ; Flow Cytometry ; G2 Phase Cell Cycle Checkpoints/drug effects ; Gas Chromatography-Mass Spectrometry ; Humans ; S Phase Cell Cycle Checkpoints/drug effects ; Solvents/chemistry ; Time Factors
Czasopismo naukowe
Tytuł :
Survivin monomer plays an essential role in apoptosis regulation.
Autorzy :
Pavlyukov MS; Shemiakin-Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya 16/10, Moscow 117997, Russia.
Antipova NV
Balashova MV
Vinogradova TV
Kopantzev EP
Shakhparonov MI
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Źródło :
The Journal of biological chemistry [J Biol Chem] 2011 Jul 01; Vol. 286 (26), pp. 23296-307. Date of Electronic Publication: 2011 May 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*physiology
Inhibitor of Apoptosis Proteins/*metabolism
Protein Multimerization/*physiology
Apoptosis Regulatory Proteins ; Caspases/genetics ; Caspases/metabolism ; Cell Line, Tumor ; Humans ; Inhibitor of Apoptosis Proteins/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Mutation ; Protein Stability ; Survivin ; Tubulin/genetics ; Tubulin/metabolism ; X-Linked Inhibitor of Apoptosis Protein/genetics ; X-Linked Inhibitor of Apoptosis Protein/metabolism
Czasopismo naukowe
Tytuł :
Analysis of apoptosis and DNA damage in bovine cumulus cells after exposure in vitro to different zinc concentrations.
Autorzy :
Anchordoquy JM; Instituto de Gentica Veterinaria Prof. Fernando N. Dulout IGEVET, UNLPCONICET, Facultad de Ciencias Veterinarias FCV, Universidad Nacional de La Plata UNLP, Calle 60 y 118 sn, La Plata 1900, Buenos Aires, Argentina.
Picco SJ
Seoane A
Anchordoquy JP
Ponzinibbio MV
Mattioli GA
Peral García P
Furnus CC
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Źródło :
Cell biology international [Cell Biol Int] 2011 Jun; Vol. 35 (6), pp. 593-7.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
DNA Damage*
Cumulus Cells/*drug effects
Zinc/*pharmacology
Animals ; Cattle ; Cells, Cultured ; Comet Assay ; Cumulus Cells/metabolism ; Female
Czasopismo naukowe
Tytuł :
Microcin J25-Ga induces apoptosis in mammalian cells by inhibiting mitochondrial RNA-polymerase.
Autorzy :
Niklison-Chirou MV; Departamento de Bioquímica de la Nutrición, Instituto Superior de Investigaciones Biológicas, CONICET-UNT, Instituto de Química Biológica Dr Bernabe Bloj, San Miguel de Tucumán, Argentina.
Dupuy F
Saavedra L
Hebert E
Banchio C
Minahk C
Morero RD
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Źródło :
Peptides [Peptides] 2011 Apr; Vol. 32 (4), pp. 832-4. Date of Electronic Publication: 2011 Jan 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*drug effects
Bacteriocins/*pharmacology
DNA-Directed RNA Polymerases/*antagonists & inhibitors
Mitochondria/*enzymology
Animals ; COS Cells ; Chlorocebus aethiops
Czasopismo naukowe
Tytuł :
Apoptosis markers related to pathogenesis of pediatric chronic hepatitis C virus infection: M30 mirrors the severity of steatosis.
Autorzy :
Valva P; Laboratory of Molecular Biology, Pathology Division, Ricardo Gutiérrez Children's Hospital, Buenos Aires, Argentina. />De Matteo E
Galoppo MC
Gismondi MI
Preciado MV
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Źródło :
Journal of medical virology [J Med Virol] 2010 May; Vol. 82 (6), pp. 949-57.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Fat Necrosis/*diagnosis
Hepatitis C, Chronic/*complications
Hepatitis C, Chronic/*pathology
Liver/*pathology
Liver/*virology
Adolescent ; Biomarkers ; Biopsy ; Caspase 3/analysis ; Child ; Child, Preschool ; Fat Necrosis/pathology ; Female ; Hepatitis C, Chronic/diagnosis ; Histocytochemistry ; Humans ; Immunohistochemistry ; In Situ Nick-End Labeling ; Infant ; Keratin-18/analysis ; Male ; Viral Nonstructural Proteins/analysis
Czasopismo naukowe
Tytuł :
Mitochondrial-dependent apoptosis in Huntington's disease human cybrids.
Autorzy :
Ferreira IL; Center for Neuroscience and Cell Biology, Faculty of Medicine, University of Coimbra, 3004-504 Coimbra, Portugal.
Nascimento MV
Ribeiro M
Almeida S
Cardoso SM
Grazina M
Pratas J
Santos MJ
Januário C
Oliveira CR
Rego AC
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Źródło :
Experimental neurology [Exp Neurol] 2010 Apr; Vol. 222 (2), pp. 243-55. Date of Electronic Publication: 2010 Jan 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*physiology
Huntington Disease/*pathology
Huntington Disease/*physiopathology
Mitochondria/*metabolism
Multienzyme Complexes/*metabolism
Adult ; Analysis of Variance ; Apoptosis/drug effects ; Apoptosis Inducing Factor/metabolism ; Apoptosis Regulatory Proteins/metabolism ; Bcl-2-Like Protein 11 ; Case-Control Studies ; Caspase 3/metabolism ; Cell Line, Tumor ; Citrate (si)-Synthase/metabolism ; DNA, Mitochondrial/metabolism ; Dose-Response Relationship, Drug ; Electron Transport Complex III/metabolism ; Electron Transport Complex IV/metabolism ; Enzyme Inhibitors/pharmacology ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Humans ; Huntington Disease/genetics ; Intracellular Fluid/metabolism ; L-Lactate Dehydrogenase/metabolism ; Membrane Potential, Mitochondrial/drug effects ; Membrane Potential, Mitochondrial/genetics ; Membrane Potential, Mitochondrial/physiology ; Membrane Proteins/metabolism ; Mitochondria/drug effects ; Nitrobenzoates/pharmacology ; Proto-Oncogene Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Reactive Oxygen Species/metabolism ; Staurosporine/pharmacology ; Subcellular Fractions/metabolism ; Superoxides/metabolism ; Teratocarcinoma ; Time Factors ; Trinucleotide Repeat Expansion/genetics ; bcl-2 Homologous Antagonist-Killer Protein/metabolism ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe
Tytuł :
Apoptosis markers in liver biopsy of nonalcoholic steatohepatitis in pediatric patients.
Autorzy :
Valva P; Laboratory of Molecular Biology, Pathology Division, Ricardo Gutiérrez Children Hospital, C1425EFD Buenos Aires, Argentina. />De Matteo E
Galoppo M
Pedreira A
Giacove G
Lezama C
Marco I
Galoppo MC
Preciado MV
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Źródło :
Human pathology [Hum Pathol] 2008 Dec; Vol. 39 (12), pp. 1816-22. Date of Electronic Publication: 2008 Aug 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Caspase 3/*metabolism
Fatty Liver/*pathology
Hepatocytes/*pathology
Keratin-18/*metabolism
Liver/*pathology
Adolescent ; Alanine Transaminase/blood ; Aspartate Aminotransferases/blood ; Biomarkers/metabolism ; Biopsy ; Child ; Child, Preschool ; Fatty Liver/classification ; Fatty Liver/metabolism ; Female ; Fluorescent Antibody Technique, Direct ; Hepatocytes/metabolism ; Humans ; Infant ; Liver/metabolism ; Liver Function Tests ; Male
Czasopismo naukowe
Tytuł :
In vivo 5-fluorouracil-[corrected]induced apoptosis on murine thymocytes: involvement of FAS, Bax and Caspase3.
Autorzy :
Aquino Esperanza JA; Faculty of Medicine, Biochemistry, Northeast National University, Moreno 1240, Corrientes 3400, Argentina.
Aguirre MV
Aispuru GR
Lettieri CN
Juaristi JA
Alvarez MA
Brandan NC
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Źródło :
Cell biology and toxicology [Cell Biol Toxicol] 2008 Oct; Vol. 24 (5), pp. 411-22. Date of Electronic Publication: 2008 Feb 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis*
Caspase 3/*metabolism
Fluorouracil/*pharmacology
Thymus Gland/*cytology
bcl-2-Associated X Protein/*metabolism
fas Receptor/*metabolism
Animals ; Antimetabolites, Antineoplastic/pharmacology ; Antineoplastic Agents/pharmacology ; DNA Damage ; DNA Fragmentation ; Female ; Mice ; Microscopy, Electron, Scanning ; Models, Biological ; Thymus Gland/drug effects ; Thymus Gland/metabolism
Czasopismo naukowe
Tytuł :
MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation.
Autorzy :
Guijarro MV; Experimental Therapeutics Programme, Centro Nacional de Investigaciones Oncológicas, Madrid 28029, Spain.
Link W
Rosado A
Leal JF
Carnero A
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Źródło :
Carcinogenesis [Carcinogenesis] 2007 Dec; Vol. 28 (12), pp. 2443-50. Date of Electronic Publication: 2007 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apoptosis/*physiology
Membrane Proteins/*physiology
Phosphatidylinositol 3-Kinases/*physiology
Proto-Oncogene Proteins c-akt/*physiology
Proto-Oncogene Proteins c-myc/*physiology
Caspase 3/metabolism ; Cell Line ; Cell Survival ; Culture Media, Serum-Free ; Enzyme Activation ; Fibroblasts/metabolism ; Humans ; Mitochondria/metabolism ; PTEN Phosphohydrolase/metabolism ; Phosphorylation ; Protein Transport ; Reactive Oxygen Species/metabolism ; Signal Transduction/physiology ; bcl-2-Associated X Protein/metabolism
Czasopismo naukowe

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