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Tytuł :
The contribution of TFPIα to the hemostatic response to injury in mice.
Autorzy :
Marar TT; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Martinez ND; Versiti Blood Research Institute, Milwaukee, WI, USA.
Maroney SA; Versiti Blood Research Institute, Milwaukee, WI, USA.
Siebert AE; Versiti Blood Research Institute, Milwaukee, WI, USA.
Wu J; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Stalker TJ; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Tomaiuolo M; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Delacroix S; Department of Medicine, University of Adelaide, Adelaide, Australia.
Simari RD; Department of Cardiovascular Medicine, University of Kansas School of Medicine, Kansas City, KS, USA.
Mast AE; Versiti Blood Research Institute, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
Brass LF; Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Sep; Vol. 19 (9), pp. 2182-2192. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Hemostatics*/pharmacology
Animals ; Blood Coagulation ; Hemostasis ; Mice ; Platelet Activation ; Thrombin/pharmacology
Czasopismo naukowe
Tytuł :
Intrauterine lethality in Tfpi gene disrupted mice is differentially suppressed during mid- and late-gestation by platelet TFPIα overexpression.
Autorzy :
Siebert AE; Versiti Blood Research Institute, Milwaukee, WI, USA.
Maroney SA; Versiti Blood Research Institute, Milwaukee, WI, USA.
Martinez ND; Versiti Blood Research Institute, Milwaukee, WI, USA.
Mast AE; Versiti Blood Research Institute, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2021 Jun; Vol. 19 (6), pp. 1483-1492. Date of Electronic Publication: 2021 Apr 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Blood Platelets*
Lipoproteins*/genetics
Animals ; Embryonic Development ; Female ; Mice ; Pregnancy ; Protein Isoforms
Czasopismo naukowe
Tytuł :
Major Reservoir for Heparin-Releasable TFPIα (Tissue Factor Pathway Inhibitor α) Is Extracellular Matrix.
Autorzy :
Peterson JA; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Maroney SA; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Martinez ND; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).
Mast AE; Versiti Blood Research Institute, Milwaukee, WI (J.A.P., S.A.M., N.D.M., A.E.M.).; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI (A.E.M.).
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Źródło :
Arteriosclerosis, thrombosis, and vascular biology [Arterioscler Thromb Vasc Biol] 2021 Jun; Vol. 41 (6), pp. 1942-1955. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Endothelial Cells/*metabolism
Extracellular Matrix/*metabolism
Kidney/*blood supply
Lipoproteins/*metabolism
Proteoglycans/*metabolism
Binding Sites ; Binding, Competitive ; Cell Adhesion Molecules/metabolism ; Cell Line ; Endothelial Cells/drug effects ; Extracellular Matrix/drug effects ; Glypicans/metabolism ; Heparin/pharmacology ; Human Umbilical Vein Endothelial Cells/drug effects ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Protein Binding ; Protein Isoforms ; Syndecan-4/metabolism ; Thrombospondins/metabolism
Czasopismo naukowe
Tytuł :
Tissue factor pathway inhibitor is required for cerebrovascular development in mice.
Autorzy :
Maroney SA; Versiti Blood Research Institute, Milwaukee, WI.
Westrick RJ; Department of Biological Sciences and.; Center for Data Science and Big Data Analytics, Oakland University, Rochester, MI.; Life Sciences Institute.
Cleuren AC; Life Sciences Institute.; Department of Internal Medicine.; Department of Human Genetics.; Department of Pediatrics, and.
Martinez ND; Versiti Blood Research Institute, Milwaukee, WI.
Siebert AE; Versiti Blood Research Institute, Milwaukee, WI.
Zogg M; Versiti Blood Research Institute, Milwaukee, WI.
Ginsburg D; Life Sciences Institute.; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI; and.
Weiler H; Versiti Blood Research Institute, Milwaukee, WI.; Department of Physiology and.
Mast AE; Versiti Blood Research Institute, Milwaukee, WI.; Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, WI.
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Źródło :
Blood [Blood] 2021 Jan 14; Vol. 137 (2), pp. 258-268.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Vessels/*embryology
Brain/*blood supply
Brain/*embryology
Embryonic Development/*physiology
Lipoproteins/*metabolism
Animals ; Factor V/metabolism ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł :
Modelling the domestic poultry population in the United States: A novel approach leveraging remote sensing and synthetic data methods.
Autorzy :
Patyk KA; United States Department of Agriculture, Animal Plant and Health Inspection Service, Veterinary Services, Strategy and Policy, Center for Epidemiology and Animal Health. .
McCool-Eye MJ; United States Department of Agriculture, Animal Plant and Health Inspection Service, Veterinary Services, Strategy and Policy, Center for Epidemiology and Animal Health. .
South DD; United States Department of Agriculture, Animal Plant and Health Inspection Service, Veterinary Services, Strategy and Policy, Center for Epidemiology and Animal Health. .
Burdett CL; Colorado State University, Department of Environmental and Radiological Health Sciences, Fort Collins, CO. .
Maroney SA; Colorado State University, Department of Environmental and Radiological Health Sciences, Fort Collins, CO. susan.a.maroney@usda.gov.
Fox A; United States Department of Agriculture, Animal Plant and Health Inspection Service, Veterinary Services, Strategy and Policy, Center for Epidemiology and Animal Health. .
Kuiper G; Colorado State University, Department of Environmental and Radiological Health Sciences, Fort Collins, CO. .
Magzamen S; Colorado State University, Department of Environmental and Radiological Health Sciences, Fort Collins, CO. .
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Źródło :
Geospatial health [Geospat Health] 2020 Dec 10; Vol. 15 (2). Date of Electronic Publication: 2020 Dec 10.
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Poultry*
Remote Sensing Technology*
Animals ; Datasets as Topic ; Disease Outbreaks ; Influenza in Birds/epidemiology ; Poultry Diseases/epidemiology ; United States
Czasopismo naukowe
Tytuł :
Measurement of plasma and platelet tissue factor pathway inhibitor, factor V and Protein S in people with haemophilia.
Autorzy :
Ellery PER; Blood Research Institute, Versiti, Milwaukee, WI, USA.; School of Pharmacy and Biomedical Sciences, Curtin University, Perth, WA, Australia.
Hilden I; Global Drug Discovery, Novo Nordisk, MȧlØv, Denmark.
Thyregod P; CMC Development, Novo Nordisk, Bagsvaerd, Denmark.
Martinez ND; Blood Research Institute, Versiti, Milwaukee, WI, USA.
Maroney SA; Blood Research Institute, Versiti, Milwaukee, WI, USA.
Gill JC; Blood Research Institute, Versiti, Milwaukee, WI, USA.
Mast AE; Blood Research Institute, Versiti, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
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Źródło :
Haemophilia : the official journal of the World Federation of Hemophilia [Haemophilia] 2019 Nov; Vol. 25 (6), pp. 1083-1091. Date of Electronic Publication: 2019 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets/*metabolism
Factor V/*metabolism
Hemophilia A/*blood
Hemophilia B/*blood
Lipoproteins/*blood
Plasma/*metabolism
Protein S/*metabolism
Adolescent ; Adult ; Aged ; Child ; Child, Preschool ; Female ; Humans ; Male ; Middle Aged ; Young Adult
Czasopismo naukowe
Tytuł :
Assessing Blood Clotting and Coagulation Factors in Mice.
Autorzy :
Brake MA; Department of Biological Sciences, Oakland University, Rochester, Michigan.
Ivanciu L; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.; Divison of Hematology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin.
Martinez ND; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin.
Westrick RJ; Department of Biological Sciences, Oakland University, Rochester, Michigan.; Center for Data Science and Big Data Analysis, Center for Biomedical Research, Oakland University, Rochester, Michigan.
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Źródło :
Current protocols in mouse biology [Curr Protoc Mouse Biol] 2019 Jun; Vol. 9 (2), pp. e61. Date of Electronic Publication: 2019 Mar 15.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Coagulation*
Blood Coagulation Factors/*metabolism
Blood Coagulation Tests/*methods
Mice/*blood
Animals ; Blood Coagulation Tests/instrumentation ; Mice, Inbred Strains ; Tail ; Time Factors
Czasopismo naukowe
Tytuł :
Erratum to: "Erratum to: Plasma proteolytic cascade activation during neonatal cardiopulmonary bypass surgery".
Autorzy :
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Peterson JA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Zwifelhofer W; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Martinez ND; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Yan K; Department of Pediatrics, Division of Quantitative Health Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Niebler RA; Department of Pediatrics, Division of Critical Care, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.; Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.
Stuth EAE; Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Anesthesiology, Division of Pediatric Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Scott JP; Department of Pediatrics, Division of Critical Care, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.; Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Anesthesiology, Division of Pediatric Anesthesiology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Bercovitz RS; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Pediatrics, Division of Quantitative Health Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Woods RK; Herma Heart Institute, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Surgery, Division of Pediatric Congenital Cardiac Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2019 Jan; Vol. 119 (1), pp. 187. Date of Electronic Publication: 2018 Dec 31.
Typ publikacji :
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł :
Erratum to: Plasma proteolytic cascade activation during neonatal cardiopulmonary bypass surgery.
Autorzy :
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Peterson JA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Zwifelhofer W; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Martinez ND; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Yan K; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Ra N; Medical College of Wisconsin, Department of Anesthesiology, Section of Pediatric Anesthesiology, Milwaukee, Wisconsin, United States.
Stuth E; Medical College of Wisconsin, Department of Pediatrics, Section of Pediatric Critical Care, Milwaukee, Wisconsin, United States.
Scott JP; Medical College of Wisconsin, Department of Anesthesiology, Section of Pediatric Anesthesiology, Milwaukee, Wisconsin, United States.; Medical College of Wisconsin, Department of Pediatrics, Section of Pediatric Critical Care, Milwaukee, Wisconsin, United States.
Bercovitz RS; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Woods RK; HermaHeart Center, Division of Pediatric Cardiothoracic Surgery, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2018 Nov; Vol. 118 (11), pp. 2009. Date of Electronic Publication: 2018 Oct 24.
Typ publikacji :
Journal Article; Published Erratum
Czasopismo naukowe
Tytuł :
Heparin-protamine balance after neonatal cardiopulmonary bypass surgery.
Autorzy :
Peterson JA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
Zwifelhofer W; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
Wood JP; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
Yan K; Departments of Pathology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Bercovitz RS; Departments of Pathology and Pediatrics, Medical College of Wisconsin, Milwaukee, WI, USA.
Woods RK; HermaHeart Center, Division of Pediatric Cardiothoracic Surgery, Children's Hospital of Wisconsin, Milwaukee, WI, USA.; Department of Surgery, Medical College of Wisconsin, Milwaukee, WI, USA.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2018 Oct; Vol. 16 (10), pp. 1973-1983. Date of Electronic Publication: 2018 Aug 16.
Typ publikacji :
Journal Article; Observational Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anticoagulants/*administration & dosage
Blood Coagulation/*drug effects
Cardiopulmonary Bypass/*adverse effects
Heparin/*administration & dosage
Heparin Antagonists/*administration & dosage
Postoperative Hemorrhage/*etiology
Protamines/*administration & dosage
Anticoagulants/adverse effects ; Anticoagulants/blood ; Blood Coagulation Tests ; Drug Monitoring/methods ; Female ; Heparin/adverse effects ; Heparin/blood ; Heparin Antagonists/adverse effects ; Heparin Antagonists/blood ; Humans ; Infant, Newborn ; Male ; Postoperative Hemorrhage/blood ; Postoperative Hemorrhage/diagnosis ; Predictive Value of Tests ; Prospective Studies ; Protamines/adverse effects ; Protamines/blood ; Risk Factors ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Plasma Proteolytic Cascade Activation during Neonatal Cardiopulmonary Bypass Surgery.
Autorzy :
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Peterson JA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Zwifelhofer W; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Martinez ND; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Yan K; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Bercovitz RS; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Pediatrics, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Pathology, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Woods RK; Division of Pediatric Cardiothoracic Surgery, Herma Heart Center, Children's Hospital of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Surgery, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin, United States.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2018 Sep; Vol. 118 (9), pp. 1545-1555. Date of Electronic Publication: 2018 Aug 07.
Typ publikacji :
Journal Article
MeSH Terms :
Cardiopulmonary Bypass*
Anticoagulants/*blood
Blood Coagulation/*drug effects
Heparin/*therapeutic use
Lipoproteins/*blood
Female ; Hemorrhage/etiology ; Humans ; Infant, Newborn ; Male ; Peptide Hydrolases/blood ; Plasma/metabolism ; Postoperative Complications ; Protein Binding ; Thrombin/metabolism
Czasopismo naukowe
Tytuł :
Suppressive Role of Tissue Factor Pathway Inhibitor-α in Platelet-Dependent Fibrin Formation under Flow Is Restricted to Low Procoagulant Strength.
Autorzy :
Thomassen S; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Mastenbroek TG; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Swieringa F; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.; Department of Protein Dynamics, ISAS Leibnitz Institute Dortmund, Dortmund, Germany.
Winckers K; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Feijge MAH; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Schrijver R; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Cosemans JMEM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, Wisconsin, United States.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, Michigan, United States.
Hackeng TM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
Heemskerk JWM; Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands.
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Źródło :
Thrombosis and haemostasis [Thromb Haemost] 2018 Mar; Vol. 118 (3), pp. 502-513. Date of Electronic Publication: 2018 Feb 16.
Typ publikacji :
Journal Article
MeSH Terms :
Blood Platelets/*drug effects
Coagulants/*chemistry
Factor VIIa/*chemistry
Factor Xa/*chemistry
Fibrin/*chemistry
Lipoproteins/*chemistry
Animals ; Anticoagulants/chemistry ; Blood Coagulation ; Blood Platelets/cytology ; Collagen/chemistry ; Crosses, Genetic ; Female ; Healthy Volunteers ; Hemophilia A/blood ; Hemophilia B/blood ; Heterozygote ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Perfusion ; Thromboplastin/chemistry ; Thrombosis
Czasopismo naukowe
Tytuł :
Correlates of plasma and platelet tissue factor pathway inhibitor, factor V, and Protein S.
Autorzy :
Ellery PER; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA.; School of Biomedical Sciences, Curtin University, Perth, Australia.
Hilden I; Global Research, Novo Nordisk, Maaloev, Denmark.
Sejling K; Global Research, Novo Nordisk, Maaloev, Denmark.
Loftager M; Global Research, Novo Nordisk, Maaloev, Denmark.
Martinez ND; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA.
Maroney SA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA.
Mast AE; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
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Źródło :
Research and practice in thrombosis and haemostasis [Res Pract Thromb Haemost] 2018 Jan; Vol. 2 (1), pp. 93-104. Date of Electronic Publication: 2017 Dec 29.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Reduced Prothrombinase Inhibition by Tissue Factor Pathway Inhibitor Contributes to the Factor V Leiden Hypercoagulable State.
Autorzy :
Wood JP; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, 53226.
Baumann Kreuziger LM; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, 53226.; Department of Medicine, Hematology and Oncology, Medical College of Wisconsin, Milwaukee, WI, 53226.
Ellery PER; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, 53226.
Maroney SA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, 53226.
Mast AE; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI, 53226.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, 53226.
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Źródło :
Blood advances [Blood Adv] 2017 Feb 14; Vol. 1 (6), pp. 386-395.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Targeting TFPI for hemophilia treatment.
Autorzy :
Peterson JA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI.
Maroney SA; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI.
Mast AE; Blood Research Institute, BloodCenter of Wisconsin, Milwaukee, WI; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI. Electronic address: .
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Źródło :
Thrombosis research [Thromb Res] 2016 May; Vol. 141 Suppl 2, pp. S28-30.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Molecular Targeted Therapy*/methods
Blood Coagulation/*drug effects
Hemophilia A/*drug therapy
Hemophilia B/*drug therapy
Lipoproteins/*antagonists & inhibitors
Lipoproteins/*metabolism
Animals ; Drug Discovery/methods ; Factor IX/metabolism ; Factor VIII/metabolism ; Hemophilia A/blood ; Hemophilia A/metabolism ; Hemophilia B/blood ; Hemophilia B/metabolism ; Hemorrhage/blood ; Hemorrhage/drug therapy ; Hemorrhage/metabolism ; Humans ; Lipoproteins/analysis
Czasopismo naukowe
Tytuł :
A balance between TFPI and thrombin-mediated platelet activation is required for murine embryonic development.
Autorzy :
Ellery PE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI;
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI;
Cooley BC; Department of Orthopedic Surgery, Medical College of Wisconsin, Milwaukee, WI;
Luyendyk JP; Department of Pathobiology and Diagnostic Investigation, Michigan State University, East Lansing, MI; and.
Zogg M; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI;
Weiler H; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI; Department of Physiology, and.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI.
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Źródło :
Blood [Blood] 2015 Jun 25; Vol. 125 (26), pp. 4078-84. Date of Electronic Publication: 2015 May 07.
Typ publikacji :
Journal Article
MeSH Terms :
Embryonic Development/*physiology
Lipoproteins/*metabolism
Mice/*embryology
Platelet Activation/*physiology
Thrombin/*metabolism
Animals ; Mice, Knockout
Czasopismo naukowe
Tytuł :
New insights into the biology of tissue factor pathway inhibitor.
Autorzy :
Maroney SA; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.
Mast AE; Blood Research Institute, Blood Center of Wisconsin, Milwaukee, WI, USA.; Department of Cell Biology, Neurobiology and Anatomy, Medical College of Wisconsin, Milwaukee, WI, USA.
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Źródło :
Journal of thrombosis and haemostasis : JTH [J Thromb Haemost] 2015 Jun; Vol. 13 Suppl 1, pp. S200-7.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Blood Coagulation*
Lipoproteins/*metabolism
Animals ; Blood Coagulation Disorders, Inherited/blood ; Blood Coagulation Disorders, Inherited/genetics ; Disease Models, Animal ; Genetic Predisposition to Disease ; Hemophilia A/blood ; Hemophilia A/drug therapy ; Hemophilia A/genetics ; Hemorrhage/genetics ; Hemorrhage/prevention & control ; Hemostasis/drug effects ; Hemostatics/therapeutic use ; Humans ; Lipoproteins/antagonists & inhibitors ; Lipoproteins/chemistry ; Lipoproteins/deficiency ; Lipoproteins/genetics ; Phenotype ; Protein Conformation ; Structure-Activity Relationship
Czasopismo naukowe

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