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Wyszukujesz frazę ""Mast Cells"" wg kryterium: Temat


Tytuł :
Identification of mast cells as a candidate significant target of immunotherapy for acute myeloid leukemia.
Autorzy :
Jia M; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Zhang H; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Wang L; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Zhao L; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Fan S; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
Xi Y; Department of Hematology, the First Hospital of Lanzhou University, Lanzhou, People's Republic of China.
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Źródło :
Hematology (Amsterdam, Netherlands) [Hematology] 2021 Dec; Vol. 26 (1), pp. 284-294.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*pharmacology
Leukemia, Myeloid, Acute/*drug therapy
Mast Cells/*drug effects
Small Molecule Libraries/*pharmacology
Antineoplastic Agents/chemistry ; Drug Discovery ; Gene Expression Profiling ; Humans ; Immunotherapy ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/immunology ; Mast Cells/immunology ; Mast Cells/metabolism ; Molecular Targeted Therapy ; Small Molecule Libraries/chemistry ; Transcriptome/drug effects
Czasopismo naukowe
Tytuł :
ATP/IL-33-triggered hyperactivation of mast cells results in an amplified production of pro-inflammatory cytokines and eicosanoids.
Autorzy :
Jordan PM; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Jena, Germany.
Andreas N; Institute of Immunology, Jena University Hospital, Jena, Germany.
Groth M; CF DNA Sequencing, Fritz Lipmann Institute, Jena, Germany.
Wegner P; Institute of Immunology, Jena University Hospital, Jena, Germany.
Weber F; Institute of Immunology, Jena University Hospital, Jena, Germany.
Jäger U; Institute of Immunology, Jena University Hospital, Jena, Germany.
Küchler C; Institute of Immunology, Jena University Hospital, Jena, Germany.
Werz O; Department of Pharmaceutical/Medicinal Chemistry, Institute of Pharmacy, Friedrich Schiller University Jena, Jena, Germany.
Serfling E; Department of Molecular Pathology, Institute of Pathology, University Würzburg, Würzburg, Germany.
Kamradt T; Institute of Immunology, Jena University Hospital, Jena, Germany.
Dudeck A; Institute for Molecular and Clinical Immunology, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany.; Health Campus Immunology, Infectiology and Inflammation, Medical Faculty, Otto-von-Guericke Universität Magdeburg, Magdeburg, Germany.
Drube S; Institute of Immunology, Jena University Hospital, Jena, Germany.
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Źródło :
Immunology [Immunology] 2021 Nov; Vol. 164 (3), pp. 541-554. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Triphosphate/*metabolism
Hypersensitivity/*immunology
Interleukin-33/*metabolism
Mast Cells/*immunology
Animals ; Anti-Allergic Agents/pharmacology ; Anti-Allergic Agents/therapeutic use ; Cell Degranulation/drug effects ; Cytokines/metabolism ; Disease Models, Animal ; Eicosanoids/metabolism ; Humans ; Hypersensitivity/drug therapy ; Interleukin-1 Receptor-Like 1 Protein/antagonists & inhibitors ; Interleukin-1 Receptor-Like 1 Protein/metabolism ; Interleukin-33/antagonists & inhibitors ; Lipidomics ; Mast Cells/drug effects ; Mast Cells/metabolism ; Mice ; Mice, Knockout ; NFATC Transcription Factors/genetics ; Primary Cell Culture ; Receptors, Purinergic P2X7/metabolism ; Signal Transduction/drug effects ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
The passively sensitized mast cell activation test is a reliable diagnostic for chlorhexidine allergy.
Autorzy :
Elst J; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Moonen N; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
van der Poorten MM; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium; Department of Paediatrics, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Faber MA; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Van Gasse AL; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium; Department of Paediatrics, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Garvey LH; Allergy Clinic, Department of Dermatology and Allergy, Gentofte Hospital, Copenhagen, Denmark; Department of Clinical Medicine, University of Copenhagen, Denmark.
Bridts CH; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
De Puysseleyr LP; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Mertens C; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Hagendorens MM; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium; Department of Paediatrics, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium.
Sabato V; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium; Department of Immunology and Allergology, AZ Jan Palfijn Gent, Ghent, Belgium.
Ebo DG; Department of Immunology, Allergology, and Rheumatology, Faculty of Medicine and Health Sciences, Infla-Med Centre of Excellence, University of Antwerp, Antwerp University Hospital, Antwerp, Belgium; Department of Immunology and Allergology, AZ Jan Palfijn Gent, Ghent, Belgium. Electronic address: .
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Źródło :
The journal of allergy and clinical immunology. In practice [J Allergy Clin Immunol Pract] 2021 Oct; Vol. 9 (10), pp. 3826-3828.e2. Date of Electronic Publication: 2021 Jun 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Hypersensitivity*
Mast Cells*
Chlorhexidine ; Humans ; Immunoglobulin E
Czasopismo naukowe
Tytuł :
FAK inhibitor PF-431396 suppresses IgE-mediated mast cell activation and allergic inflammation in mice.
Autorzy :
Chen JJ; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China. Electronic address: .
Zhang LN; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Wang HN; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Xie CC; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Li WY; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Gao P; Shenzhen University General Hospital, Shenzhen 518060, China.
Hu WZ; Shenzhen University General Hospital, Shenzhen 518060, China.
Zhao ZF; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China.
Ji K; Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Laboratory Department of South China Hospital, Health Science Center, Shenzhen University, Shenzhen 518060, China. Electronic address: .
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Źródło :
Biochemical pharmacology [Biochem Pharmacol] 2021 Oct; Vol. 192, pp. 114722. Date of Electronic Publication: 2021 Aug 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Focal Adhesion Kinase 1/*antagonists & inhibitors
Focal Adhesion Kinase 1/*metabolism
Hypersensitivity/*metabolism
Immunoglobulin E/*toxicity
Mast Cells/*metabolism
Protein Kinase Inhibitors/*pharmacology
Animals ; Cells, Cultured ; Dose-Response Relationship, Drug ; Female ; Focal Adhesion Kinase 1/immunology ; Hypersensitivity/drug therapy ; Hypersensitivity/immunology ; Mast Cells/drug effects ; Mast Cells/immunology ; Mice ; Mice, Inbred BALB C ; Protein Kinase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł :
Metabolic Consequences of IgE- and Non-IgE-Mediated Mast Cell Degranulation.
Autorzy :
Mendoza RP; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO.
Anderson CC; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO.
Fudge DH; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO.
Roede JR; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO.
Brown JM; Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO .
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Źródło :
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2021 Dec 01; Vol. 207 (11), pp. 2637-2648. Date of Electronic Publication: 2021 Nov 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Immunoglobulin E/*metabolism
Mast Cells/*metabolism
Animals ; Cells, Cultured ; Immunoglobulin E/immunology ; Mast Cells/immunology ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Multimodal fluorescently labeled polymer-coated GdF 3 nanoparticles inhibit degranulation in mast cells.
Autorzy :
Shapoval O; Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
Sulimenko V; Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Klebanovych A; Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Rabyk M; Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
Shapoval P; Department of Physical, Analytical and General Chemistry, Lviv Polytechnic National University, Sv. Yura Sq. 9, 79013 Lviv, Ukraine.
Kaman O; Institute of Physics of the Czech Academy of Sciences, Cukrovarnická 112/10, 162 00 Prague 6, Czech Republic.
Rydvalová E; Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
Filipová M; Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
Dráberová E; Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Dráber P; Laboratory of Biology of Cytoskeleton, Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, 142 20 Prague 4, Czech Republic.
Horák D; Institute of Macromolecular Chemistry of the Czech Academy of Sciences, Heyrovského nám. 2, 162 06 Prague 6, Czech Republic.
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Źródło :
Nanoscale [Nanoscale] 2021 Nov 25; Vol. 13 (45), pp. 19023-19037. Date of Electronic Publication: 2021 Nov 25.
Typ publikacji :
Journal Article
MeSH Terms :
Mast Cells*
Nanoparticles*
Animals ; Cell Degranulation ; Growth Differentiation Factor 3 ; Humans ; Mice ; Polymers ; Rats
Czasopismo naukowe
Tytuł :
Anti-allergic property of 4,8-sphingadienine stereoisomers in vivo and in vitro model.
Autorzy :
Shimizu H; Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe, 657-8501, Japan.
Kuse M; Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe, 657-8501, Japan.
Minato KI; Department of Applied Biological Chemistry, Graduate School of Agriculture, Meijo University, 1-501, Shiogamaguchi, Nagoya, 468-8502, Japan.
Mizuno M; Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, 1-1, Rokkodai-cho, Nada-ku, Kobe, 657-8501, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Nov 05; Vol. 577, pp. 32-37. Date of Electronic Publication: 2021 Sep 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Allergic Agents/*pharmacology
Cell Degranulation/*drug effects
Ethanolamines/*pharmacology
Mast Cells/*drug effects
Passive Cutaneous Anaphylaxis/*drug effects
Animals ; Anti-Allergic Agents/chemistry ; Caco-2 Cells ; Cell Line, Tumor ; Ear/pathology ; Edema/prevention & control ; Ethanolamines/chemistry ; Ethanolamines/metabolism ; Female ; Glucosylceramides/chemistry ; Glucosylceramides/metabolism ; Glucosylceramides/pharmacology ; Humans ; Mast Cells/physiology ; Mice, Inbred BALB C ; Molecular Structure ; Plant Extracts/chemistry ; Plant Extracts/pharmacology ; Rats ; Stereoisomerism
Czasopismo naukowe
Tytuł :
Role of Mast Cells in the Pathogenesis of Pruritus in Mastocytosis.
Autorzy :
Kwiatkowska D
Reich A; Department of Dermatology, University of Rzeszow, Ul. Szopena 2, PL-35-055 Rzeszów, Poland. .
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Źródło :
Acta dermato-venereologica [Acta Derm Venereol] 2021 Oct 31; Vol. 101 (10), pp. adv00583. Date of Electronic Publication: 2021 Oct 31.
Typ publikacji :
Journal Article
MeSH Terms :
Mast Cells*
Mastocytosis*/diagnosis
Humans ; Pruritus/diagnosis ; Pruritus/etiology ; Quality of Life ; Skin
Czasopismo naukowe
Tytuł :
Hybrids between H 2 S-donors and betamethasone 17-valerate or triamcinolone acetonide inhibit mast cell degranulation and promote hyperpolarization of bronchial smooth muscle cells.
Autorzy :
Giordano F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Corvino A; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Scognamiglio A; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Citi V; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Gorica E; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Fattorusso C; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Persico M; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Caliendo G; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Fiorino F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Magli E; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Perissutti E; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Santagada V; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Severino B; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy.
Pavese RC; Genetic S.p.A, Via Della Monica 26, Castel San Giorgio, SA, Italy.
Petti F; Genetic S.p.A, Via Della Monica 26, Castel San Giorgio, SA, Italy.
Martelli A; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Calderone V; Department of Pharmacy, University of Pisa, Via B. Pisano 5, Pisa, Italy.
Frecentese F; Department of Pharmacy, University of Naples «Federico II», Via D. Montesano 49, Naples, Italy. Electronic address: .
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113517. Date of Electronic Publication: 2021 May 05.
Typ publikacji :
Journal Article
MeSH Terms :
Betamethasone Valerate/*pharmacology
Bronchi/*drug effects
Hydrogen Sulfide/*pharmacology
Mast Cells/*drug effects
Myocytes, Smooth Muscle/*drug effects
Triamcinolone Acetonide/*pharmacology
Betamethasone Valerate/chemistry ; Bronchi/metabolism ; Cells, Cultured ; Dose-Response Relationship, Drug ; Humans ; Hydrogen Sulfide/chemistry ; Mast Cells/metabolism ; Models, Molecular ; Molecular Structure ; Myocytes, Smooth Muscle/metabolism ; Structure-Activity Relationship ; Triamcinolone Acetonide/chemistry
Czasopismo naukowe
Tytuł :
Mast cell disorders: A framework of allergy and hematology symptoms leading to personalized treatments.
Autorzy :
Castells MC; Drug Hypersensitivity and Desensitization Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; Mastocytosis Center, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address: .
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Źródło :
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology [Ann Allergy Asthma Immunol] 2021 Oct; Vol. 127 (4), pp. 403-404.
Typ publikacji :
Editorial
MeSH Terms :
Anaphylaxis/*diagnosis
Mast Cells/*metabolism
Mastocytosis/*diagnosis
Mastocytosis/*genetics
Tryptases/*genetics
Anaphylaxis/pathology ; Humans ; Hypersensitivity/immunology ; Mast Cells/immunology ; Mastocytosis/drug therapy ; Mastocytosis/pathology ; Precision Medicine/methods ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins c-kit/genetics ; Social Media
Opinia redakcyjna
Tytuł :
Sputum mast cell/basophil gene expression relates to inflammatory and clinical features of severe asthma.
Autorzy :
Winter NA; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia.
Qin L; Department of Respiratory Medicine, Department of Pulmonary and Critical Care Medicine, Xiangya Hospital, Central South University, Changsha, China.
Gibson PG; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia; Department of Respiratory and Sleep Medicine, John Hunter Hospital, Hunter Medical Research Institute, Newcastle, Australia.
McDonald VM; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Nursing and Midwifery, The University of Newcastle, Newcastle, Australia.
Baines KJ; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia.
Faulkner J; Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, Newcastle, Australia.
Evans TJ; Clinical Research Design, IT and Statistical Support Unit, Hunter Medical Research Institute, Newcastle, Australia.
Fricker M; National Health and Medical Research Council Centre for Research Excellence in Severe Asthma, Newcastle, Australia; The Priority Research Centre for Health Lungs, The University of Newcastle, Newcastle, Australia; School of Medicine and Public Health, The University of Newcastle, Newcastle, Australia. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 428-438. Date of Electronic Publication: 2021 Feb 18.
Typ publikacji :
Clinical Trial; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
MeSH Terms :
Asthma*/immunology
Asthma*/pathology
Basophils*/immunology
Basophils*/pathology
Mast Cells*/immunology
Mast Cells*/pathology
Gene Expression Regulation/*immunology
Sputum/*immunology
Adult ; Aged ; Female ; Humans ; Inflammation/immunology ; Inflammation/pathology ; Male ; Middle Aged ; Severity of Illness Index
Czasopismo naukowe
Tytuł :
Study of Antibody-Dependent Reactions of Mast Cells In Vitro and in a Model of Severe Influenza Infection in Mice.
Autorzy :
Mamontov A; Immunology Department, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
Losev I; Virology Department, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
Korzhevskii D; Department of General and Special Morphology, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
Guselnikova V; Department of General and Special Morphology, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
Polevshchikov A; Immunology Department, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
Desheva Y; Virology Department, Federal State Budgetary Scientific Institution «Institute of Experimental Medicine», Saint Petersburg, Russia.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Jul 14; Vol. 12, pp. 689436. Date of Electronic Publication: 2021 Jul 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Degranulation*/drug effects
Histamine Release*/drug effects
Antibodies, Viral/*blood
Immunoglobulin G/*blood
Influenza A Virus, H1N1 Subtype/*immunology
Influenza A Virus, H5N1 Subtype/*immunology
Lung/*immunology
Mast Cells/*immunology
Orthomyxoviridae Infections/*immunology
Animals ; Disease Models, Animal ; Female ; Histamine Antagonists/pharmacology ; Host-Pathogen Interactions ; Immunogenicity, Vaccine ; Influenza A Virus, H1N1 Subtype/pathogenicity ; Influenza A Virus, H5N1 Subtype/pathogenicity ; Influenza Vaccines/administration & dosage ; Lung/drug effects ; Lung/metabolism ; Lung/virology ; Mast Cells/drug effects ; Mast Cells/metabolism ; Mast Cells/virology ; Mice, Inbred CBA ; Orthomyxoviridae Infections/blood ; Orthomyxoviridae Infections/drug therapy ; Orthomyxoviridae Infections/virology ; Severity of Illness Index ; Time Factors ; Vaccination
Czasopismo naukowe
Tytuł :
Selective expression of a C-type lectin receptor, Clec12b, on skin mast cells.
Autorzy :
Iijima A; Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Japan; Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan.
Kanemaru K; Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan.
Wang Y; Ph.D. Program in Human Biology, School of Integrative and Global Majors, University of Tsukuba, Japan.
Nabekura T; Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan.
Nakamura Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Japan.
Fujisawa Y; Department of Dermatology, Faculty of Medicine, University of Tsukuba, Japan.
Mori D; Centre d'Immunologie de Marseille-Luminy, Aix Marseille Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Marseille, France; Centre d'Immunophénomique, Aix Marseille Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Marseille, France.
Ohmuraya M; Department of Genetics, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
Yamasaki S; Department of Molecular Immunology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan; Laboratory of Molecular Immunology, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan; Division of Molecular Design, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Fukuoka, Japan.
Tahara-Hanaoka S; Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan.
Shibuya A; Department of Immunology, Faculty of Medicine, University of Tsukuba, Japan; Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA), University of Tsukuba, Japan; R&D Center for Innovative Drug Discovery, University of Tsukuba, Japan. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2021 Jul 05; Vol. 561, pp. 101-105. Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal/*immunology
Lectins, C-Type/*metabolism
Mast Cells/*metabolism
Receptors, Mitogen/*metabolism
Skin/*metabolism
Animals ; Cell Differentiation ; Cells, Cultured ; Flow Cytometry/methods ; Humans ; Lectins, C-Type/immunology ; Mast Cells/cytology ; Mast Cells/immunology ; Mice ; Receptors, Mitogen/immunology ; Skin/cytology ; Skin/immunology
Czasopismo naukowe
Tytuł :
Study on degranulation of mast cells under C48/80 treatment by electroporation-assisted and ultrasound-assisted surface-enhanced Raman spectrascopy.
Autorzy :
Zheng M; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Lin Y; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Xu J; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Gao J; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Gong W; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Xie S; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China.
Yu Y; College of Integrated Traditional Chinese and Western Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian, China. Electronic address: .
Lin J; MOE Key Laboratory of Optoelectronic Science and Technology for Medicine and Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou, Fujian, China; School of opto-electronic and Communication Engineering, Xiamen University of Technology, Xiamen, Fujian, China. Electronic address: .
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Źródło :
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2022 Jan 15; Vol. 265, pp. 120331. Date of Electronic Publication: 2021 Aug 27.
Typ publikacji :
Journal Article
MeSH Terms :
Mast Cells*
Metal Nanoparticles*
Discriminant Analysis ; Electroporation ; Principal Component Analysis ; Spectrum Analysis, Raman
Czasopismo naukowe
Tytuł :
Annexin A1 Mimetic Peptide Ac 2-26 Modulates the Function of Murine Colonic and Human Mast Cells.
Autorzy :
Oliveira MP; Laboratory of Interdisciplinary Medical Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil.
Prates J; Department of Biology, Institute of Bioscience, Humanities and Exact Science, São Paulo State University (Unesp), São José do Rio Preto, Brazil.
Gimenes AD; Department of Functional Morphology, Faceres School of Medicine, São José do Rio Preto, Brazil.
Correa SG; Departamento de Bioquímica Clinica-Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI - CONICET) - Facultad de Ciencias Quimicas- Universidad Nacional de Córdoba (UNC), Córdoba, Argentina.
Oliani SM; Department of Biology, Institute of Bioscience, Humanities and Exact Science, São Paulo State University (Unesp), São José do Rio Preto, Brazil.; Advanced Research Center in Medicine, CEPAM -Unilago, São José do Rio Preto, Brazil.; Federal University of São Paulo, Post Graduate Program in Structural and Functional Biology, Escola Paulista de Medicina (Unifesp-EPM), São Paulo, Brazil.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Sep 07; Vol. 12, pp. 689484. Date of Electronic Publication: 2021 Sep 07 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Annexin A1/*pharmacology
Cell Degranulation/*drug effects
Colon/*drug effects
Cytokines/*metabolism
Inflammation Mediators/*metabolism
Mast Cells/*drug effects
Peptides/*pharmacology
Animals ; Cell Line ; Colon/immunology ; Colon/metabolism ; Humans ; Interleukin-4/genetics ; Interleukin-4/metabolism ; Male ; Mast Cells/immunology ; Mast Cells/metabolism ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Formyl Peptide/metabolism ; Tissue Culture Techniques
Czasopismo naukowe
Tytuł :
Detection of drug-specific immunoglobulin E (IgE) and acute mediator release for the diagnosis of immediate drug hypersensitivity reactions.
Autorzy :
Brockow K; Department of Dermatology and Allergy Biederstein, School of Medicine, Technical University of Munich, Munich, Germany. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Sep; Vol. 496, pp. 113101. Date of Electronic Publication: 2021 Jul 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Immunologic Tests*
Basophils/*drug effects
Cell Degranulation/*drug effects
Drug Hypersensitivity/*diagnosis
Histamine Release/*drug effects
Hypersensitivity, Immediate/*diagnosis
Immunoglobulin E/*blood
Mast Cells/*drug effects
Animals ; Antibody Specificity ; Basophils/immunology ; Basophils/metabolism ; Biomarkers/blood ; Drug Hypersensitivity/blood ; Drug Hypersensitivity/immunology ; Humans ; Hypersensitivity, Immediate/blood ; Hypersensitivity, Immediate/immunology ; Mast Cells/immunology ; Mast Cells/metabolism ; Predictive Value of Tests ; Risk Factors
Czasopismo naukowe
Tytuł :
Association of Mast Cell Burden and TIM-3 Expression with Recalcitrant Chronic Rhinosinusitis with Nasal Polyps.
Autorzy :
Belsky MA; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Corredera E; University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Banerjee H; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Moore J; Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Wang L; Clinical and Translational Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.
Kane LP; Department of Immunology, University of Pittsburgh, Pittsburgh, PA, USA.
Lee SE; Department of Otolaryngology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
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Źródło :
The Annals of otology, rhinology, and laryngology [Ann Otol Rhinol Laryngol] 2021 Sep; Vol. 130 (9), pp. 1069-1077. Date of Electronic Publication: 2021 Feb 12.
Typ publikacji :
Journal Article
MeSH Terms :
Hepatitis A Virus Cellular Receptor 2/*metabolism
Mast Cells/*pathology
Nasal Polyps/*pathology
Rhinitis/*pathology
Sinusitis/*pathology
Adult ; Cell Count ; Chronic Disease ; Endoscopy ; Female ; Flow Cytometry ; Humans ; Male ; Mast Cells/metabolism ; Middle Aged ; Nasal Mucosa/pathology ; Nasal Polyps/metabolism ; Nasal Polyps/surgery ; Nasal Surgical Procedures ; Prognosis ; Proportional Hazards Models ; Recurrence ; Rhinitis/metabolism ; Rhinitis/surgery ; Sino-Nasal Outcome Test ; Sinusitis/metabolism ; Sinusitis/surgery
Czasopismo naukowe
Tytuł :
Novel Approaches in the Inhibition of IgE-Induced Mast Cell Reactivity in Food Allergy.
Autorzy :
Tontini C; Lydia Becker Institute for Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
Bulfone-Paus S; Lydia Becker Institute for Immunology and Inflammation, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, United Kingdom.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Aug 12; Vol. 12, pp. 613461. Date of Electronic Publication: 2021 Aug 12 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Food Hypersensitivity/*therapy
Immunoglobulin E/*immunology
Mast Cells/*physiology
Antibodies, Anti-Idiotypic/therapeutic use ; Cytokines/antagonists & inhibitors ; Cytokines/physiology ; Desensitization, Immunologic ; Food Hypersensitivity/immunology ; Humans ; Mast Cells/drug effects
Czasopismo naukowe
Tytuł :
Peanut diversity and specific activity are the dominant IgE characteristics for effector cell activation in children.
Autorzy :
Hemmings O; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom.
Niazi U; Guy's and St Thomas' National Health Service Foundation Trust and King's College London National Institute for Health Research Biomedical Research Centre Translational Bioinformatics Platform, Guy's Hospital, London, United Kingdom.
Kwok M; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom.
James LK; Blizard Institute, Queen Mary University of London, London, United Kingdom.
Lack G; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom.
Santos AF; Department of Women and Children's Health (Pediatric Allergy), School of Life Course Sciences, Faculty of Life Sciences and Medicine, King's College London, London, United Kingdom; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, London, United Kingdom; Asthma UK Centre in Allergic Mechanisms of Asthma, London, United Kingdom; Children's Allergy Service, Evelina London Children's Hospital, Guy's and St Thomas' Hospital, London, United Kingdom. Electronic address: .
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Źródło :
The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2021 Aug; Vol. 148 (2), pp. 495-505.e14. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Basophils*/immunology
Basophils*/metabolism
Immunoglobulin E*/blood
Immunoglobulin E*/immunology
Mast Cells*/immunology
Mast Cells*/metabolism
Peanut Hypersensitivity*/blood
Peanut Hypersensitivity*/immunology
Antigens, Plant/*immunology
Arachis/*immunology
Adolescent ; Child ; Child, Preschool ; Female ; Flow Cytometry ; Humans ; Infant ; Male
Czasopismo naukowe
Tytuł :
Basophil and mast cell activation tests by flow cytometry in immediate drug hypersensitivity: Diagnosis and beyond.
Autorzy :
Elst J; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.
Sabato V; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium; Department of Immunology, AZ Jan Palfijn Hospital Gent, Ghent, Belgium.
van der Poorten MM; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium; Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
Van Gasse AL; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium; Department of Pediatrics, Faculty of Medicine and Health Sciences, University of Antwerp and Antwerp University Hospital, Antwerp, Belgium.
Van Houdt M; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.
Bridts CH; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.
Walschot M; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.
Timmermans JP; Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Pintelon I; Laboratory of Cell Biology and Histology, Department of Veterinary Sciences, University of Antwerp, Antwerp, Belgium.
Mertens C; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium.
Ebo DG; Department of Immunology, Allergology, Rheumatology and the Infla-Med Centre of Excellence, Faculty of Medicine and Health Sciences, University of Antwerp, Antwerp (Belgium) and Immunology, Allergology, Rheumatology, Antwerp University Hospital, Antwerp, Belgium; Department of Immunology, AZ Jan Palfijn Hospital Gent, Ghent, Belgium. Electronic address: .
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Źródło :
Journal of immunological methods [J Immunol Methods] 2021 Aug; Vol. 495, pp. 113050. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Basophil Degranulation Test*
Cell Degranulation*/drug effects
Flow Cytometry*
Basophils/*immunology
Drug Hypersensitivity/*diagnosis
Mast Cells/*immunology
Basophils/drug effects ; Basophils/metabolism ; Biomarkers/blood ; Drug Hypersensitivity/blood ; Drug Hypersensitivity/immunology ; Humans ; Immunoglobulin E/blood ; Mast Cells/drug effects ; Mast Cells/metabolism ; Nerve Tissue Proteins/blood ; Phenotype ; Predictive Value of Tests ; Receptors, G-Protein-Coupled/blood ; Receptors, Neuropeptide/blood
Czasopismo naukowe

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