- Tytuł:
- Phase I trial of neoadjuvant chemoradiotherapy (CRT) with capecitabine and weekly irinotecan followed by laparoscopic total mesorectal excision (LTME) in rectal cancer patients.
- Autorzy:
- Źródło:
- Investigational new drugs [Invest New Drugs] 2009 Jun; Vol. 27 (3), pp. 262-8. Date of Electronic Publication: 2008 Oct 16.
- Typ publikacji:
- Clinical Trial, Phase I; Journal Article
- MeSH Terms:
-
Laparoscopy*
Neoadjuvant Therapy*
Antineoplastic Agents/*therapeutic use
Camptothecin/*analogs & derivatives
Deoxycytidine/*analogs & derivativesFluorouracil /*analogs & derivatives
Rectal Neoplasms/*therapy
Aged ; Aged, 80 and over ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Camptothecin/administration & dosage ; Camptothecin/adverse effects ; Camptothecin/therapeutic use ; Capecitabine ; Combined Modality Therapy ; Deoxycytidine/administration & dosage ; Deoxycytidine/adverse effects ; Deoxycytidine/therapeutic use ; Drug Administration Schedule ; Female ;Fluorouracil /administration & dosage ;Fluorouracil /adverse effects ;Fluorouracil /therapeutic use ; Humans ; Irinotecan ; Male ; Middle Aged ; Rectal Neoplasms/drug therapy ; Rectal Neoplasms/radiotherapy ; Rectal Neoplasms/surgery ; Survival Analysis
Czasopismo naukowe