- Tytuł:
- Daidzein prevents the increase in CD4+CD28null T cells and B lymphopoesis in ovariectomized mice: a key mechanism for anti-osteoclastogenic effect.
- Autorzy:
- Źródło:
- PloS one [PLoS One] 2011; Vol. 6 (6), pp. e21216. Date of Electronic Publication: 2011 Jun 22.
- Typ publikacji:
- Journal Article; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
B-Lymphocytes/*cytology
CD28 Antigens/*metabolism
CD4-Positive T-Lymphocytes/*cytologyIsoflavones /*pharmacology
Lymphopoiesis/*drug effects
Osteoclasts/*drug effects
Osteogenesis/*drug effects
Animals ; B-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/drug effects ; Cell Proliferation/drug effects ; Coculture Techniques ; Dose-Response Relationship, Drug ; Down-Regulation/drug effects ; Female ; Femur/diagnostic imaging ; Femur/drug effects ; Heterogeneous-Nuclear Ribonucleoproteins/genetics ; Heterogeneous-Nuclear Ribonucleoproteins/metabolism ; Lymphocyte Count ; Mice ; Organ Size/drug effects ; Osteoclasts/cytology ; Ovariectomy ; Phosphoproteins/genetics ; Phosphoproteins/metabolism ; RNA-Binding Proteins/genetics ; RNA-Binding Proteins/metabolism ; Radiography ; Reactive Oxygen Species/metabolism ; Spleen/drug effects ; Spleen/pathology ; Thymus Gland/drug effects ; Thymus Gland/pathology ; Tumor Necrosis Factor-alpha/blood ; Nucleolin
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