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    Wyświetlanie 1-9 z 9
    Tytuł:
    Metal Complexes of a 5-Nitro-8-Hydroxyquinoline-Proline Hybrid with Enhanced Water Solubility Targeting Multidrug Resistant Cancer Cells.
    Autorzy:
    Pivarcsik T; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Pósa V; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Kovács H; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
    Spengler G; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Medical Microbiology, Albert Szent-Györgyi Health Center, Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
    Pósa SP; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
    Tóth S; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; National Laboratory for Drug Research and Development, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
    Nezafat Yazdi Z; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
    Özvegy-Laczka C; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.
    Ugrai I; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group, Eötvös Loránd Research Network, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
    Szatmári I; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group, Eötvös Loránd Research Network, University of Szeged, Eötvös u. 6, H-6720 Szeged, Hungary.
    Szakács G; Drug Resistance Research Group, Institute of Enzymology, Research Centre for Natural Sciences, Eötvös Loránd Research Network, Magyar Tudósok krt. 2, H-1117 Budapest, Hungary.; Institute of Cancer Research, Medical University of Vienna, Borschkegasse 8a, A-1090 Vienna, Austria.
    Enyedy ÉA; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2022 Dec 29; Vol. 24 (1). Date of Electronic Publication: 2022 Dec 29.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Coordination Complexes*/pharmacology
    Coordination Complexes*/chemistry
    Ruthenium*/chemistry
    Antineoplastic Agents*/pharmacology
    Antineoplastic Agents*/chemistry
    Organometallic Compounds*/chemistry
    Neoplasms*
    Humans ; Proline ; Solubility ; Ligands ; Drug Resistance, Multiple ; Ferric Compounds ; Drug Resistance, Neoplasm ; Water/chemistry ; Ions ; Ferrous Compounds
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Estradiol-Based Salicylaldehyde (Thio)Semicarbazones and Their Copper Complexes with Anticancer, Antibacterial and Antioxidant Activities.
    Autorzy:
    Petrasheuskaya TV; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Kovács F; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
    Igaz N; Department of Biochemistry and Molecular Biology, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.
    Rónavári A; Department of Applied and Environmental Chemistry, University of Szeged, Rerrich Béla tér 1, H-6720 Szeged, Hungary.
    Hajdu B; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Bereczki L; Institute of Materials and Environmental Chemistry, Research Centre for Natural Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary.; Centre for Structural Science, Research Centre for Natural Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar tudósok körútja 2, H-1117 Budapest, Hungary.
    Spengler G; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
    Gyurcsik B; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Kiricsi M; Department of Biochemistry and Molecular Biology, University of Szeged, Közép fasor 52, H-6726 Szeged, Hungary.
    Frank É; Department of Organic Chemistry, University of Szeged, Dóm tér 8, H-6720 Szeged, Hungary.
    Enyedy ÉA; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2022 Dec 21; Vol. 28 (1). Date of Electronic Publication: 2022 Dec 21.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Semicarbazones*/chemistry
    Coordination Complexes*/pharmacology
    Coordination Complexes*/chemistry
    Thiosemicarbazones*/pharmacology
    Thiosemicarbazones*/chemistry
    Molecular Structure ; Antioxidants/pharmacology ; Copper/chemistry ; Estradiol/pharmacology ; Anti-Bacterial Agents/pharmacology ; Crystallography, X-Ray ; Ligands
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Thiosemicarbazone Derivatives Developed to Overcome COTI-2 Resistance.
    Autorzy:
    Pósa V; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre and MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Stefanelli A; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.
    Nunes JHB; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.; Inorganic Chemistry Department, Institute of Chemistry, University of Campinas-UNICAMP, Campinas 13083-970, SP, Brazil.
    Hager S; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.; Research Cluster ''Translational Cancer Therapy Research'', 1090 Vienna, Austria.
    Mathuber M; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
    Berger W; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.; Research Cluster ''Translational Cancer Therapy Research'', 1090 Vienna, Austria.
    Keppler BK; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.; Research Cluster ''Translational Cancer Therapy Research'', 1090 Vienna, Austria.
    Kowol CR; Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria.; Research Cluster ''Translational Cancer Therapy Research'', 1090 Vienna, Austria.
    Enyedy ÉA; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre and MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Heffeter P; Center for Cancer Research, Medical University of Vienna, Borschkegasse 8a, 1090 Vienna, Austria.; Research Cluster ''Translational Cancer Therapy Research'', 1090 Vienna, Austria.
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    Źródło:
    Cancers [Cancers (Basel)] 2022 Sep 14; Vol. 14 (18). Date of Electronic Publication: 2022 Sep 14.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Solution Equilibrium Studies on Salicylidene Aminoguanidine Schiff Base Metal Complexes: Impact of the Hybridization with L-Proline on Stability, Redox Activity and Cytotoxicity.
    Autorzy:
    Dömötör O; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
    Gál GT; Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
    Spengler G; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis u. 6, H-6725 Szeged, Hungary.
    Dobrova A; Institute of Inorganic Chemistry, University of Vienna, Währinger Strasse 42, A-1090 Vienna, Austria.
    Arion VB; Institute of Inorganic Chemistry, University of Vienna, Währinger Strasse 42, A-1090 Vienna, Austria.
    Enyedy ÉA; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2022 Mar 22; Vol. 27 (7). Date of Electronic Publication: 2022 Mar 22.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Coordination Complexes*/chemistry
    Coordination Complexes*/pharmacology
    Schiff Bases*/chemistry
    Schiff Bases*/pharmacology
    Crystallography, X-Ray ; Ferric Compounds ; Ferrous Compounds ; Guanidines ; Humans ; Ligands ; Oxidation-Reduction ; Proline
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    8-Hydroxyquinoline-Amino Acid Hybrids and Their Half-Sandwich Rh and Ru Complexes: Synthesis, Anticancer Activities, Solution Chemistry and Interaction with Biomolecules.
    Autorzy:
    Pivarcsik T; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.
    Dömötör O; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.
    Mészáros JP; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
    Spengler G; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.; Department of Medical Microbiology, Albert Szent-Györgyi Health Center and Albert Szent-Györgyi Medical School, University of Szeged, Semmelweis U. 6, H-6725 Szeged, Hungary.
    Csuvik O; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group of Hungarian Academy of Sciences, University of Szeged, Eötvös U. 6, H-6720 Szeged, Hungary.
    Szatmári I; Institute of Pharmaceutical Chemistry and Stereochemistry Research Group of Hungarian Academy of Sciences, University of Szeged, Eötvös U. 6, H-6720 Szeged, Hungary.
    Enyedy ÉA; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm Tér 7, H-6720 Szeged, Hungary.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2021 Oct 19; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 19.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Amino Acids/*chemistry
    Antineoplastic Agents/*pharmacology
    Colonic Neoplasms/*drug therapy
    Coordination Complexes/*pharmacology
    Oxyquinoline/*chemistry
    Rhodium/*chemistry
    Ruthenium/*chemistry
    Antineoplastic Agents/chemistry ; Apoptosis ; Cell Proliferation ; Colonic Neoplasms/pathology ; Coordination Complexes/chemistry ; Humans ; Tumor Cells, Cultured
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Estrone-salicylaldehyde N-methylated thiosemicarbazone hybrids and their copper complexes: solution structure, stability and anticancer activity in tumour spheroids.
    Autorzy:
    Petrasheuskaya TV; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary.
    Wernitznig D; Institute of Inorganic Chemistry and Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Währinger Straße 42, Vienna, Austria.
    Kiss MA; Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, 6720, Hungary.
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, 1117, Hungary.
    Wenisch D; Institute of Inorganic Chemistry and Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Währinger Straße 42, Vienna, Austria.
    Keppler BK; Institute of Inorganic Chemistry and Research Cluster 'Translational Cancer Therapy Research', University of Vienna, Währinger Straße 42, Vienna, Austria.
    Frank É; Department of Organic Chemistry, University of Szeged, Dóm tér 8, Szeged, 6720, Hungary.
    Enyedy ÉA; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary. .; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, Szeged, 6720, Hungary. .
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    Źródło:
    Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry [J Biol Inorg Chem] 2021 Oct; Vol. 26 (7), pp. 775-791. Date of Electronic Publication: 2021 Aug 28.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antineoplastic Agents*/pharmacology
    Coordination Complexes*/pharmacology
    Neoplasms*
    Thiosemicarbazones*/pharmacology
    Aldehydes ; Copper ; Crystallography, X-Ray ; Estrone ; Humans ; Ligands
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Binding Models of Copper(II) Thiosemicarbazone Complexes with Human Serum Albumin: A Speciation Study.
    Autorzy:
    May NV; Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary.
    Jancsó A; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
    Enyedy ÉA; Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.; MTA-SZTE Lendület Functional Metal Complexes Research Group, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary.
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    Źródło:
    Molecules (Basel, Switzerland) [Molecules] 2021 May 05; Vol. 26 (9). Date of Electronic Publication: 2021 May 05.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Copper/*metabolism
    Serum Albumin, Human/*metabolism
    Thiosemicarbazones/*metabolism
    Anisotropy ; Computer Simulation ; Humans ; Oligopeptides/chemistry ; Oxidation-Reduction ; Protein Binding ; Pyridines/chemistry ; Solutions ; Spectrophotometry, Ultraviolet ; Thiosemicarbazones/chemistry ; Time Factors
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Crystal structures of zinc(II) complexes with β-hydroxypyridinecarboxylate ligands: examples of structure-directing effects used in inorganic crystal engineering.
    Autorzy:
    May NV; Centre for Structural Sciences, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary.
    Nys K; Department of Chemistry, University of Antwerp, Universiteitsplein 1, Antwerpen, B-2610, Belgium.
    Ching HYV; Department of Chemistry, University of Antwerp, Universiteitsplein 1, Antwerpen, B-2610, Belgium.
    Bereczki L; Centre for Structural Sciences, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary.
    Holczbauer T; Centre for Structural Sciences, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary.
    Di Marco VB; Department of Chemical Sciences, University of Padova, via Marzolo 1, Padova, 35131, Italy.
    Bombicz P; Centre for Structural Sciences, Research Centre for Natural Sciences, Magyar tudósok körútja 2, Budapest, H-1117, Hungary.
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    Źródło:
    Acta crystallographica Section B, Structural science, crystal engineering and materials [Acta Crystallogr B Struct Sci Cryst Eng Mater] 2021 Apr 01; Vol. 77 (Pt 2), pp. 193-204. Date of Electronic Publication: 2021 Feb 27.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    High Enzyme Activity of a Binuclear Nickel Complex Formed with the Binding Loops of the NiSOD Enzyme*.
    Autorzy:
    Kelemen D; Department of Inorganic and Analytical Chemistry, University of Debrecen, 4032, Debrecen, Hungary.
    May NV; Research Centre for Natural Sciences, 1117, Budapest, Hungary.
    Andrási M; Department of Inorganic and Analytical Chemistry, University of Debrecen, 4032, Debrecen, Hungary.
    Gáspár A; Department of Inorganic and Analytical Chemistry, University of Debrecen, 4032, Debrecen, Hungary.
    Fábián I; Department of Inorganic and Analytical Chemistry, University of Debrecen, 4032, Debrecen, Hungary.; MTA-DE Redox and Homogeneous Catalytic Reaction Mechanisms, Research Group, University of Debrecen, 4032, Debrecen, Hungary.
    Lihi N; Department of Inorganic and Analytical Chemistry, University of Debrecen, 4032, Debrecen, Hungary.; MTA-DE Redox and Homogeneous Catalytic Reaction Mechanisms, Research Group, University of Debrecen, 4032, Debrecen, Hungary.
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    Źródło:
    Chemistry (Weinheim an der Bergstrasse, Germany) [Chemistry] 2020 Dec 15; Vol. 26 (70), pp. 16767-16773. Date of Electronic Publication: 2020 Nov 09.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Nickel/*chemistry
    Superoxide Dismutase/*chemistry
    Superoxide Dismutase/*metabolism
    Ligands ; Oxidation-Reduction ; Superoxides/chemistry ; Superoxides/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-9 z 9

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