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Wyszukujesz frazę ""McColl, Barry W."" wg kryterium: Autor


Wyświetlanie 1-12 z 12
Tytuł :
Neutrophil infiltration to the brain is platelet-dependent, and is reversed by blockade of platelet GPIbα.
Autorzy :
Giles JA; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Greenhalgh AD; Centre for Research in Neuroscience, Montreal General Hospital, McGill University Health Centre, Montreal, QC, Canada.
Denes A; 'Momentum' Laboratory of Neuroimmunology, Institute of Experimental Medicine, Budapest, Hungary.
Nieswandt B; Department of Vascular Medicine, University Hospital and Rudolf Virchow Centre for Experimental Biomedicine, University of Würzburg, Würzburg, Germany.
Coutts G; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
McColl BW; The Roslin Institute & R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, UK.; Edinburgh Medical School, UK Dementia Research Institute at The University of Edinburgh, Edinburgh, UK.
Allan SM; Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
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Źródło :
Immunology [Immunology] 2018 Jun; Vol. 154 (2), pp. 322-328. Date of Electronic Publication: 2018 Feb 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Blood Platelets/*drug effects
Blood Platelets/*metabolism
Brain/*immunology
Brain/*metabolism
Neutrophil Infiltration/*immunology
Neutrophils/*immunology
Neutrophils/*metabolism
Platelet Glycoprotein GPIb-IX Complex/*antagonists & inhibitors
Animals ; Antibodies, Monoclonal/pharmacology ; Brain/pathology ; Chemokine CCL5/genetics ; Chemokine CCL5/metabolism ; Chemokine CXCL1/genetics ; Chemokine CXCL1/metabolism ; Disease Models, Animal ; Immunoglobulin G/immunology ; Immunoglobulin G/pharmacology ; Inflammation/genetics ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation/pathology ; Lipopolysaccharides/immunology ; Mice
Czasopismo naukowe
Tytuł :
Isolation and Phenotyping of Adult Mouse Microglial Cells.
Autorzy :
Grabert K; The Roslin Institute and R(D)SVS, University of Edinburgh, Edinburgh, UK. .
McColl BW; The Roslin Institute and R(D)SVS, University of Edinburgh, Edinburgh, UK.; Dementia Research Institute, Edinburgh Medical School, University of Edinburgh, Edinburgh, UK.
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2018; Vol. 1784, pp. 77-86.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*cytology
Cell Culture Techniques/*methods
Cell Separation/*methods
Microglia/*cytology
Animals ; Flow Cytometry ; Mice ; Myelin Sheath/chemistry ; Phagocytosis/drug effects ; Povidone/chemistry ; Silicon Dioxide/chemistry
Czasopismo naukowe
Tytuł :
Microglial brain region-dependent diversity and selective regional sensitivities to aging.
Autorzy :
Grabert K; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Michoel T; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Karavolos MH; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Clohisey S; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Baillie JK; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Stevens MP; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Freeman TC; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
Summers KM; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
McColl BW; The Roslin Institute, University of Edinburgh, Easter Bush, Midlothian, UK.
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Źródło :
Nature neuroscience [Nat Neurosci] 2016 Mar; Vol. 19 (3), pp. 504-16. Date of Electronic Publication: 2016 Jan 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Aging/*physiology
Brain/*physiology
Microglia/*physiology
Aging/genetics ; Animals ; Mice ; Phenotype ; Transcriptome
Czasopismo naukowe
Tytuł :
Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity.
Autorzy :
Giles JA; Faculty of Life Sciences, University of Manchester, Manchester, UK.
Greenhalgh AD
Davies CL
Denes A
Shaw T
Coutts G
Rothwell NJ
McColl BW
Allan SM
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Źródło :
European journal of immunology [Eur J Immunol] 2015 Feb; Vol. 45 (2), pp. 525-30. Date of Electronic Publication: 2014 Nov 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*immunology
Encephalitis/*immunology
Interleukin-1alpha/*genetics
Interleukin-1beta/*genetics
Microglia/*immunology
Signal Transduction/*immunology
Animals ; Brain/pathology ; Encephalitis/chemically induced ; Encephalitis/genetics ; Encephalitis/pathology ; Gene Expression Regulation ; Immunity, Innate ; Injections, Intraventricular ; Interleukin-1alpha/deficiency ; Interleukin-1alpha/immunology ; Interleukin-1beta/deficiency ; Interleukin-1beta/immunology ; Lipopolysaccharides ; Lung/immunology ; Mice ; Mice, Knockout ; Microglia/pathology ; Neutrophil Infiltration ; Neutrophils/immunology ; Neutrophils/pathology ; Organ Specificity ; Peritoneum/immunology
Czasopismo naukowe
Tytuł :
Increased brain microvascular MMP-9 and incidence of haemorrhagic transformation in obese mice after experimental stroke.
Autorzy :
McColl BW; Faculty of Life Sciences, University of Manchester, Manchester, UK.
Rose N
Robson FH
Rothwell NJ
Lawrence CB
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Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2010 Feb; Vol. 30 (2), pp. 267-72. Date of Electronic Publication: 2009 Oct 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain/*pathology
Cerebral Hemorrhage/*etiology
Matrix Metalloproteinase 9/*biosynthesis
Obesity/*complications
Stroke/*complications
Animals ; Blood-Brain Barrier/physiopathology ; Brain/blood supply ; Brain/enzymology ; Capillary Permeability/physiology ; Cerebral Hemorrhage/epidemiology ; Cerebral Hemorrhage/pathology ; Cerebrovascular Circulation/physiology ; Immunohistochemistry ; Incidence ; Male ; Mice ; Mice, Obese ; Stroke/pathology
Czasopismo naukowe
Tytuł :
Targeted deletion of the mitogen-activated protein kinase kinase 4 gene in the nervous system causes severe brain developmental defects and premature death.
Autorzy :
Wang X; Faculty of Life Sciences, Wellcome Trust Center for Cell-Matrix Research, University of Manchester, Michael Smith Building, Oxford Road, Manchester M13 9PT, United Kingdom.
Nadarajah B
Robinson AC
McColl BW
Jin JW
Dajas-Bailador F
Boot-Handford RP
Tournier C
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Źródło :
Molecular and cellular biology [Mol Cell Biol] 2007 Nov; Vol. 27 (22), pp. 7935-46. Date of Electronic Publication: 2007 Sep 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Brain*/abnormalities
Brain*/embryology
Brain*/enzymology
Brain*/growth & development
Gene Deletion*
JNK Mitogen-Activated Protein Kinases/*metabolism
MAP Kinase Kinase 4/*genetics
MAP Kinase Signaling System/*physiology
Animals ; Cell Movement/physiology ; Enzyme Activation ; Female ; Isoenzymes/genetics ; Isoenzymes/metabolism ; JNK Mitogen-Activated Protein Kinases/genetics ; MAP Kinase Kinase 4/metabolism ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins/metabolism ; Neurofilament Proteins/metabolism ; Neuroglia/cytology ; Neuroglia/physiology ; Neurons/cytology ; Neurons/physiology ; Phenotype ; Pregnancy
Czasopismo naukowe
Tytuł :
APOE epsilon3 gene transfer attenuates brain damage after experimental stroke.
Autorzy :
McColl BW; Wellcome Surgical Institute, Division of Clinical Neuroscience, University of Glasgow, Garscube Estate, Glasgow, UK.
McGregor AL
Wong A
Harris JD
Amalfitano A
Magnoni S
Baker AH
Dickson G
Horsburgh K
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Źródło :
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism [J Cereb Blood Flow Metab] 2007 Mar; Vol. 27 (3), pp. 477-87. Date of Electronic Publication: 2006 Jun 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Therapy*
Apolipoprotein E3/*genetics
Brain/*pathology
Stroke/*therapy
Adenoviridae ; Animals ; Apolipoprotein E3/metabolism ; Apolipoprotein E3/therapeutic use ; Enzyme-Linked Immunosorbent Assay ; Gene Transfer Techniques ; Genetic Vectors ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Humans ; Immunohistochemistry ; Mice ; Stroke/pathology
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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