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    Tytuł:
    Assessing the clinical value of faecal bile acid profiling to predict recurrence in primary Clostridioides difficile infection.
    Autorzy:
    Mullish BH; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.; Departments of Gastroenterology and Hepatology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
    Martinez-Gili L; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.; Section of Bioinformatics, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
    Chekmeneva E; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, National Phenome Centre, IRDB Building, Hammersmith House Campus, Imperial College London, London, UK.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
    Correia GDS; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, National Phenome Centre, IRDB Building, Hammersmith House Campus, Imperial College London, London, UK.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
    Lewis MR; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, National Phenome Centre, IRDB Building, Hammersmith House Campus, Imperial College London, London, UK.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
    Horneffer-Van Der Sluis V; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, National Phenome Centre, IRDB Building, Hammersmith House Campus, Imperial College London, London, UK.; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Department for Diagnostics, Institute for Clinical Chemistry and Laboratory Medicine, University Hospital Hamburg-Eppendorf, Hamburg, Germany.
    Roberts LA; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.
    McDonald JAK; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK.
    Pechlivanis A; Section of Bioanalytical Chemistry, Division of Systems Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; Laboratory of Analytical Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.; Biomic_Auth, Bioanalysis and Omics Laboratory, Center for Interdisciplinary Research and Innovation (CIRI-AUTH), Thessaloniki, Greece.
    Walters JRF; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.; Departments of Gastroenterology and Hepatology, St Mary's Hospital, Imperial College Healthcare NHS Trust, London, UK.
    McClure EL; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.
    Marchesi JR; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, London, UK.
    Allegretti JR; Division of Gastroenterology, Hepatology, and Endoscopy, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA.
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    Źródło:
    Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2022 Dec; Vol. 56 (11-12), pp. 1556-1569. Date of Electronic Publication: 2022 Oct 17.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Clostridioides difficile*
    Clostridium Infections*/diagnosis
    Clostridium Infections*/drug therapy
    Clostridium Infections*/microbiology
    Humans ; Male ; Middle Aged ; Female ; Bile Acids and Salts/analysis ; Recurrence ; Feces/chemistry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Effects of bowel preparation on intestinal bacterial associated urine and faecal metabolites and the associated faecal microbiome.
    Autorzy:
    Powles STR; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK. .; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK. .
    Gallagher KI; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Chong LWL; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Alexander JL; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Mullish BH; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Hicks LC; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    McDonald JAK; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; MRC Centre for Molecular Bacteriology and Infection, Flowers Building, Imperial College London, London, SW7 2AZ, UK.
    Marchesi JR; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Williams HRT; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
    Orchard TR; Department of Metabolism, Digestion and Reproduction, Imperial College London, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.; Department of Gastroenterology, Imperial College Healthcare NHS Trust, St. Mary's Hospital, Praed Street, London, W2 1NY, UK.
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    Źródło:
    BMC gastroenterology [BMC Gastroenterol] 2022 May 13; Vol. 22 (1), pp. 240. Date of Electronic Publication: 2022 May 13.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Gastrointestinal Microbiome*
    Microbiota*
    Feces/chemistry ; Humans ; Intestines/microbiology ; RNA, Ribosomal, 16S/analysis ; RNA, Ribosomal, 16S/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    A Multi-Factorial Observational Study on Sequential Fecal Microbiota Transplant in Patients with Medically Refractory Clostridioides difficile Infection.
    Autorzy:
    Monaghan TM; NIHR Nottingham Biomedical Research Centre, University of Nottingham, Nottingham NG7 2UH, UK.; Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.
    Duggal NA; MRC-Arthritis Research UK Centre for Musculoskeletal Ageing Research, Institute of Inflammation and Ageing, University of Birmingham, Birmingham B15 2TT, UK.
    Rosati E; Institute of Clinical Molecular Biology, Universitätsklinikum Schleswig-Holstein, Christian-Albrecht University of Kiel, 24105 Kiel, Germany.
    Griffin R; Nottingham Digestive Diseases Centre, School of Medicine, University of Nottingham, Nottingham NG7 2UH, UK.; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham NG7 2RD, UK.
    Hughes J; Synthetic Biology Research Centre, The University of Nottingham Biodiscovery Institute, University of Nottingham, Nottingham NG7 2RD, UK.
    Roach B; Division of Gastroenterology, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
    Yang DY; Division of Gastroenterology, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
    Wang C; Division of Gastroenterology, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
    Wong K; Division of Gastroenterology, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
    Saxinger L; Division of Infectious Diseases, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
    Pučić-Baković M; Glycoscience Research Laboratory, Genos Ltd., Borongajska cesta 83H, 10000 Zagreb, Croatia.
    Vučković F; Glycoscience Research Laboratory, Genos Ltd., Borongajska cesta 83H, 10000 Zagreb, Croatia.
    Klicek F; Glycoscience Research Laboratory, Genos Ltd., Borongajska cesta 83H, 10000 Zagreb, Croatia.
    Lauc G; Glycoscience Research Laboratory, Genos Ltd., Borongajska cesta 83H, 10000 Zagreb, Croatia.; Faculty of Pharmacy and Biochemistry, University of Zagreb, 10000 Zagreb, Croatia.
    Tighe P; School of Life Sciences, University of Nottingham, Nottingham NG7 2RD, UK.
    Mullish BH; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.
    Blanco JM; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.
    McDonald JAK; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London SW7 2AZ, UK.
    Marchesi JR; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London SW7 2AZ, UK.
    Xue N; School of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2UH, UK.
    Dottorini T; School of Veterinary Medicine and Science, University of Nottingham, Nottingham NG7 2UH, UK.
    Acharjee A; College of Medical and Dental Sciences, Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham B15 2TT, UK.
    Franke A; Institute of Clinical Molecular Biology, Universitätsklinikum Schleswig-Holstein, Christian-Albrecht University of Kiel, 24105 Kiel, Germany.
    Li Y; Shenzhen Digital Life Institute, Shenzhen 518016, China.
    Wong GK; Department of Biological Sciences, Department of Medicine, University of Alberta, Edmonton, AB T6G 2E1, Canada.
    Polytarchou C; Department of Biosciences, John van Geest Cancer Research Centre, Centre for Health Aging and Understanding Disease, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.
    Yau TO; Department of Biosciences, John van Geest Cancer Research Centre, Centre for Health Aging and Understanding Disease, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.
    Christodoulou N; Department of Biosciences, John van Geest Cancer Research Centre, Centre for Health Aging and Understanding Disease, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.
    Hatziapostolou M; Department of Biosciences, John van Geest Cancer Research Centre, Centre for Health Aging and Understanding Disease, School of Science and Technology, Nottingham Trent University, Nottingham NG11 8NS, UK.
    Wang M; Shenzhen Digital Life Institute, Shenzhen 518016, China.; Innovation Lab, Innovent Biologics, Inc., Suzhou 215011, China.
    Russell LA; Division of Gastroenterology, Department of Medicine, McMaster University, Hamilton, ON L8N 3Z5, Canada.
    Kao DH; Division of Gastroenterology, Department of Medicine, University of Alberta; Edmonton, Alberta, AB T6G 2G3, Canada.
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    Źródło:
    Cells [Cells] 2021 Nov 19; Vol. 10 (11). Date of Electronic Publication: 2021 Nov 19.
    Typ publikacji:
    Journal Article; Observational Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Fecal Microbiota Transplantation*
    Clostridium Infections/*therapy
    Aged ; Aged, 80 and over ; Animals ; Antibodies, Neutralizing/metabolism ; Bacterial Toxins/immunology ; Chlorocebus aethiops ; Clostridium Infections/immunology ; Clostridium Infections/microbiology ; Cluster Analysis ; Feces/microbiology ; Female ; Gastrointestinal Microbiome ; Genomics ; Humans ; Immunosenescence ; Male ; Middle Aged ; Phylogeny ; Receptors, Antigen, T-Cell/metabolism ; Time Factors ; Treatment Outcome ; Vero Cells
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Multiomic features associated with mucosal healing and inflammation in paediatric Crohn's disease.
    Autorzy:
    Taylor H; Department of Surgery and Cancer, Imperial College London, London, UK.
    Serrano-Contreras JI; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
    McDonald JAK; MRC Centre for Molecular Bacteriology and Infection, Imperial College London, London, UK.
    Epstein J; Paediatric Gastroenterology Department, Chelsea and Westminster Hospital, London, UK.
    Fell JM; Paediatric Gastroenterology Department, Chelsea and Westminster Hospital, London, UK.
    Seoane RC; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.
    Li JV; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.
    Marchesi JR; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, UK.; School of Biosciences, University of Cardiff, Cardiff, UK.
    Hart AL; Department of Metabolism, Digestion and Reproduction, Faculty of Medicine, Imperial College London, London, UK.; IBD Unit, St. Mark's Hospital, Harrow, UK.
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    Źródło:
    Alimentary pharmacology & therapeutics [Aliment Pharmacol Ther] 2020 Nov; Vol. 52 (9), pp. 1491-1502. Date of Electronic Publication: 2020 Sep 14.
    Typ publikacji:
    Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Crohn Disease*/drug therapy
    Crohn Disease*/metabolism
    Crohn Disease*/microbiology
    Crohn Disease*/pathology
    Adolescent ; Biological Products/therapeutic use ; Biomarkers/analysis ; Child ; Child, Preschool ; Feces/chemistry ; Feces/microbiology ; Humans ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/microbiology ; Inflammation/pathology ; Intestinal Mucosa/microbiology ; Intestinal Mucosa/pathology ; Leukocyte L1 Antigen Complex/analysis ; Lysine/analysis ; Metabolome ; Peptide Hydrolases/metabolism ; Valerates/analysis ; Veillonellaceae/isolation & purification ; Wound Healing
    SCR Disease Name:
    Pediatric Crohn's disease
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Metabonomics and the Gut Microbiome Associated With Primary Response to Anti-TNF Therapy in Crohn's Disease.
    Autorzy:
    Ding NS; St Vincent's Hospital, Inflammatory Bowel Disease, Melbourne, VIC, Australia.; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    McDonald JAK; Division of Digestive Diseases, Department of Surgery and Cancer, St Mary's Hospital, Imperial College London, London, UK.
    Perdones-Montero A; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    Rees DN; Division of Digestive Diseases, Department of Surgery and Cancer, St Mary's Hospital, Imperial College London, London, UK.
    Adegbola SO; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    Misra R; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    Hendy P; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.
    Penez L; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.
    Marchesi JR; School of Biosciences, Cardiff University, Cardiff, UK.; Division of Digestive Diseases, Department of Surgery and Cancer, St Mary's Hospital, Imperial College London, London, UK.
    Holmes E; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.; Institute of Health Futures, Murdoch University, Perth, WA, Australia.
    Sarafian MH; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    Hart AL; St Mark's Hospital, Inflammatory Bowel Disease Unit, London, UK.; Division of Computational Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
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    Źródło:
    Journal of Crohn's & colitis [J Crohns Colitis] 2020 Sep 07; Vol. 14 (8), pp. 1090-1102.
    Typ publikacji:
    Journal Article
    MeSH Terms:
    Adalimumab*/administration & dosage
    Adalimumab*/adverse effects
    Crohn Disease*/diagnosis
    Crohn Disease*/drug therapy
    Crohn Disease*/epidemiology
    Crohn Disease*/immunology
    Inflammation*/blood
    Inflammation*/diagnosis
    Inflammation*/urine
    Infliximab*/administration & dosage
    Infliximab*/adverse effects
    Bile Acids and Salts/*analysis
    Cysteine/*analysis
    Histidine/*analysis
    Lipid Metabolism/*drug effects
    RNA, Ribosomal, 16S/*analysis
    Adult ; Biomarkers, Pharmacological/analysis ; Feces ; Female ; Humans ; London ; Longitudinal Studies ; Male ; Metabolomics/methods ; Predictive Value of Tests ; Tumor Necrosis Factor Inhibitors/administration & dosage ; Tumor Necrosis Factor Inhibitors/adverse effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy.
    Autorzy:
    Ovadia C; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Perdones-Montero A; Section of Biomolecular Medicine, Division of Computational & Systems Medicine, Department of Surgery & Cancer, Faculty of Medicine, Imperial College London, London, SW7 2AZ, UK.
    Fan HM; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Mullish BH; Centre for Clinical Microbiome Research and The Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Imperial College London, London, W2 1NY, UK.
    McDonald JAK; Centre for Clinical Microbiome Research and The Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Imperial College London, London, W2 1NY, UK.
    Papacleovoulou G; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Wahlström A; Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, 41345, Sweden.
    Ståhlman M; Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, 41345, Sweden.
    Tsakmaki A; Diabetes Research Group, School of Life Course Sciences, King's College London, London, SE1 1UL, UK.
    Clarke LCD; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Sklavounos A; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Dixon PH; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK.
    Bewick GA; Diabetes Research Group, School of Life Course Sciences, King's College London, London, SE1 1UL, UK.
    Walters JRF; Division of Digestive Diseases, Hammersmith Hospital, Imperial College London, London, W12 0HS, UK.
    Marschall HU; Sahlgrenska Academy, Institute of Medicine, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, 41345, Sweden.
    Marchesi JR; Centre for Clinical Microbiome Research and The Division of Integrative Systems Medicine and Digestive Disease, Department of Surgery and Cancer, Imperial College London, London, W2 1NY, UK. .; Cardiff School of Biosciences, Cardiff University, Cardiff, CF10 3XQ, UK. .
    Williamson C; Maternal and Fetal Disease Group, Department of Women and Children's Health, King's College London, London, SE1 1UL, UK. .
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    Źródło:
    Scientific reports [Sci Rep] 2020 Mar 03; Vol. 10 (1), pp. 3895. Date of Electronic Publication: 2020 Mar 03.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Regulation, Bacterial*
    Amidohydrolases/*genetics
    Bacteroidetes/*drug effects
    Bacteroidetes/*genetics
    Cholestasis, Intrahepatic/*microbiology
    Intestines/*microbiology
    Pregnancy Complications/*microbiology
    Ursodeoxycholic Acid/*pharmacology
    Animals ; Case-Control Studies ; Female ; Gastrointestinal Microbiome/drug effects ; Humans ; Mice ; Pregnancy
    SCR Disease Name:
    Intrahepatic Cholestasis of Pregnancy
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Autotaxin, bile acid profile and effect of ileal bile acid transporter inhibition in primary biliary cholangitis patients with pruritus.
    Autorzy:
    Hegade VS; Institute of Cellular Medicine and NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.
    Pechlivanis A; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    McDonald JAK; Department of Surgery and Cancer, Imperial College London, London, UK.
    Rees D; Department of Surgery and Cancer, Imperial College London, London, UK.
    Corrigan M; NIHR Biomedical Research Unit, Centre for Liver Research, University of Birmingham, Birmingham, UK.
    Hirschfield GM; NIHR Biomedical Research Unit, Centre for Liver Research, University of Birmingham, Birmingham, UK.
    Taylor-Robinson SD; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.; Department of Surgery and Cancer, Imperial College London, London, UK.
    Holmes E; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Imperial College London, London, UK.
    Marchesi JR; Department of Surgery and Cancer, Imperial College London, London, UK.; School of Biosciences, Cardiff University, Cardiff, UK.
    Kendrick S; GlaxoSmithKline (GSK), Research and Development, Hertfordshire, UK.
    Jones DE; Institute of Cellular Medicine and NIHR Newcastle Biomedical Research Centre, Newcastle University, Newcastle upon Tyne, UK.
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    Źródło:
    Liver international : official journal of the International Association for the Study of the Liver [Liver Int] 2019 May; Vol. 39 (5), pp. 967-975. Date of Electronic Publication: 2019 Feb 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Bile Acids and Salts/*blood
    Liver Cirrhosis, Biliary/*complications
    Methylamines/*pharmacology
    Phosphoric Diester Hydrolases/*blood
    Pruritus/*blood
    Pruritus/*drug therapy
    Thiazepines/*pharmacology
    Adult ; Aged ; Biomarkers/blood ; Carrier Proteins ; Case-Control Studies ; Chenodeoxycholic Acid/pharmacology ; Cholic Acid/pharmacology ; Chromatography, Liquid ; Feces/chemistry ; Feces/microbiology ; Female ; Humans ; Male ; Membrane Glycoproteins ; Middle Aged ; Pruritus/etiology ; RNA, Ribosomal, 16S/genetics ; Tandem Mass Spectrometry
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
      Wyświetlanie 1-7 z 7

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