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Wyszukujesz frazę ""McDougle RM"" wg kryterium: Autor


Wyświetlanie 1-5 z 5
Tytuł:
Characterization of the mechanism by which the RB/E2F pathway controls expression of the cancer genomic DNA deaminase APOBEC3B.
Autorzy:
Roelofs PA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Goh CY; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.
Chua BH; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Jarvis MC; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.
Stewart TA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Mater Research Institute, The University of Queensland, Faculty of Medicine, Brisbane, Australia.
McCann JL; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
McDougle RM; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Hennepin Healthcare, Minneapolis, United States.
Carpenter MA; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
Martens JW; Erasmus MC Cancer Institute, Erasmus University Medical Center, Rotterdam, Netherlands.
Span PN; Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, Netherlands.
Kappei D; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Harris RS; Department of Biochemistry, Molecular Biology and Biophysics, Masonic Cancer Center, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, United States.; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, United States.
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Źródło:
ELife [Elife] 2020 Sep 28; Vol. 9. Date of Electronic Publication: 2020 Sep 28.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Signal Transduction*
Cytidine Deaminase/*genetics
E2F Transcription Factors/*genetics
Minor Histocompatibility Antigens/*genetics
Cytidine Deaminase/metabolism ; E2F Transcription Factors/metabolism ; HEK293 Cells ; Humans ; MCF-7 Cells ; Minor Histocompatibility Antigens/metabolism ; Protein Binding
Czasopismo naukowe
Tytuł:
APOBEC3 multimerization correlates with HIV-1 packaging and restriction activity in living cells.
Autorzy:
Li J; School of Physics and Astronomy, University of Minnesota, 116 Church Street Southeast, Minneapolis, MN 55455, USA; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA.
Chen Y; School of Physics and Astronomy, University of Minnesota, 116 Church Street Southeast, Minneapolis, MN 55455, USA; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA.
Li M; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology and Biophysics, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
Carpenter MA; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology and Biophysics, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
McDougle RM; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology and Biophysics, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
Luengas EM; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology and Biophysics, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
Macdonald PJ; Department of Biomedical Engineering, University of Minnesota, 312 Church Street Southeast, Minneapolis, MN 55455, USA.
Harris RS; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biochemistry, Molecular Biology and Biophysics, 321 Church Street Southeast, Minneapolis, MN 55455, USA.
Mueller JD; School of Physics and Astronomy, University of Minnesota, 116 Church Street Southeast, Minneapolis, MN 55455, USA; Institute for Molecular Virology, University of Minnesota, 515 Delaware Street Southeast, Minneapolis, MN 55455, USA; Department of Biomedical Engineering, University of Minnesota, 312 Church Street Southeast, Minneapolis, MN 55455, USA. Electronic address: .
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Źródło:
Journal of molecular biology [J Mol Biol] 2014 Mar 20; Vol. 426 (6), pp. 1296-307. Date of Electronic Publication: 2013 Dec 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Cytosine Deaminase/*chemistry
HIV Infections/*immunology
HIV-1/*physiology
Virus Assembly/*physiology
Virus Replication/*immunology
vif Gene Products, Human Immunodeficiency Virus/*deficiency
APOBEC Deaminases ; Cytidine Deaminase ; Cytosine Deaminase/genetics ; Cytosine Deaminase/metabolism ; HIV Infections/metabolism ; HIV Infections/virology ; HeLa Cells ; Humans ; Protein Multimerization ; Virion/metabolism
Czasopismo naukowe
Tytuł:
D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B.
Autorzy:
McDougle RM; Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Center for Genome Engineering, Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
Hultquist JF
Stabell AC
Sawyer SL
Harris RS
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Źródło:
Virology [Virology] 2013 Jun 20; Vol. 441 (1), pp. 31-9. Date of Electronic Publication: 2013 Mar 29.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Cytidine Deaminase/*metabolism
HIV-1/*immunology
Amino Acid Substitution ; Animals ; Cell Line ; DNA Mutational Analysis ; Genotype ; Humans ; Macaca mulatta ; Point Mutation
Czasopismo naukowe
Tytuł:
Crystal structure of the DNA cytosine deaminase APOBEC3F: the catalytically active and HIV-1 Vif-binding domain.
Autorzy:
Bohn MF; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
Shandilya SM
Albin JS
Kouno T
Anderson BD
McDougle RM
Carpenter MA
Rathore A
Evans L
Davis AN
Zhang J
Lu Y
Somasundaran M
Matsuo H
Harris RS
Schiffer CA
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Źródło:
Structure (London, England : 1993) [Structure] 2013 Jun 04; Vol. 21 (6), pp. 1042-50. Date of Electronic Publication: 2013 May 16.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Cytosine Deaminase/*metabolism
HIV-1/*metabolism
vif Gene Products, Human Immunodeficiency Virus/*metabolism
Catalysis ; Crystallography, X-Ray ; Cytosine Deaminase/chemistry ; Models, Molecular ; Protein Conformation
Czasopismo naukowe
Tytuł:
APOBEC3B is an enzymatic source of mutation in breast cancer.
Autorzy:
Burns MB; Biochemistry, Molecular Biology and Biophysics Department, University of Minnesota, Minneapolis, Minnesota 55455, USA.
Lackey L
Carpenter MA
Rathore A
Land AM
Leonard B
Refsland EW
Kotandeniya D
Tretyakova N
Nikas JB
Yee D
Temiz NA
Donohue DE
McDougle RM
Brown WL
Law EK
Harris RS
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Źródło:
Nature [Nature] 2013 Feb 21; Vol. 494 (7437), pp. 366-70. Date of Electronic Publication: 2013 Feb 06.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Mutagenesis*/genetics
Point Mutation*/genetics
Breast Neoplasms/*enzymology
Breast Neoplasms/*genetics
Cytidine Deaminase/*metabolism
Base Sequence ; Biocatalysis ; Breast Neoplasms/pathology ; Cell Death ; Cell Line, Tumor ; Cytidine Deaminase/genetics ; DNA Damage/genetics ; DNA Fragmentation ; DNA, Neoplasm/genetics ; DNA, Neoplasm/metabolism ; Deamination ; Gene Expression Regulation, Enzymologic ; Gene Expression Regulation, Neoplastic ; Histones/metabolism ; Humans ; Minor Histocompatibility Antigens ; Phenotype ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; Up-Regulation ; Uracil/metabolism
Czasopismo naukowe
    Wyświetlanie 1-5 z 5

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