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Wyszukujesz frazę ""McIntyre RE"" wg kryterium: Autor


Wyświetlanie 1-12 z 12
Tytuł:
Gut mucosa dissociation protocols influence cell type proportions and single-cell gene expression levels.
Autorzy:
Uniken Venema WTC; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Ramírez-Sánchez AD; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Bigaeva E; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Withoff S; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Jonkers I; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
McIntyre RE; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Ghouraba M; Wellcome Sanger Institute, Hinxton, Cambridgeshire, CB10 1SA, UK.
Raine T; Department of Gastroenterology, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Weersma RK; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.
Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.
Festen EAM; Department of Gastroenterology and Hepatology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. .
van der Wijst MGP; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jun 14; Vol. 12 (1), pp. 9897. Date of Electronic Publication: 2022 Jun 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collagenases*
Intestinal Mucosa*
Flow Cytometry/methods ; Gene Expression ; Gene Expression Profiling/methods ; Peptide Hydrolases ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods
Czasopismo naukowe
Tytuł:
A Genome-Wide Association Study for Regulators of Micronucleus Formation in Mice.
Autorzy:
McIntyre RE; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Nicod J; Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK.
Robles-Espinoza CD; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK Laboratorio Internacional de Investigación sobre el Genoma Humano, Universidad Nacional Autónoma de México, Campus Juriquilla, Boulevard Juriquilla 3001, Santiago de Querétaro 76230, Mexico.
Maciejowski J; Laboratory for Cell Biology and Genetics, The Rockefeller University, New York, New York 10065.
Cai N; Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK.
Hill J; Microbial Pathogenesis, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Verstraten R; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Iyer V; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK.
Rust AG; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK Tumour Profiling Unit, The Institute of Cancer Research, London SW3 6JB, UK.
Balmus G; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK The Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, CB2 1QN, UK.
Mott R; Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK UCL Genetics Institute, University College London, WC1E 6BT, UK.
Flint J; Wellcome Trust Centre for Human Genetics, Oxford OX3 7BN, UK.
Adams DJ; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridgeshire CB10 1SA, UK .
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2016 Aug 09; Vol. 6 (8), pp. 2343-54. Date of Electronic Publication: 2016 Aug 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Chromosome Breakage*
Genome-Wide Association Study*
Micronuclei, Chromosome-Defective*
Quantitative Trait Loci/*genetics
Animals ; Chromosome Mapping ; Female ; Genomic Instability ; Genotype ; Male ; Mice ; Phenotype ; Polymorphism, Single Nucleotide ; Sex Characteristics
Czasopismo naukowe
Tytuł:
Jdp2 downregulates Trp53 transcription to promote leukaemogenesis in the context of Trp53 heterozygosity.
Autorzy:
van der Weyden L; Wellcome Trust Sanger Institute, Cambridge, UK.
Rust AG
McIntyre RE
Robles-Espinoza CD
del Castillo Velasco-Herrera M
Strogantsev R
Ferguson-Smith AC
McCarthy S
Keane TM
Arends MJ
Adams DJ
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Źródło:
Oncogene [Oncogene] 2013 Jan 17; Vol. 32 (3), pp. 397-402. Date of Electronic Publication: 2012 Feb 27.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Down-Regulation*
Heterozygote*
Transcription, Genetic*
Cell Transformation, Neoplastic/*genetics
Leukemia/*genetics
Leukemia/*pathology
Repressor Proteins/*metabolism
Tumor Suppressor Protein p53/*genetics
Animals ; HEK293 Cells ; Humans ; Lymphoma/genetics ; Lymphoma/pathology ; Mice ; NIH 3T3 Cells
Czasopismo naukowe
Tytuł:
Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1.
Autorzy:
van der Weyden L; Experimental Cancer Genetics, The Wellcome Trust Sanger Institute, Hinxton, Cambridge, CB10 1HH, UK. />Arends MJ
Rust AG
Poulogiannis G
McIntyre RE
Adams DJ
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Źródło:
Molecular cancer [Mol Cancer] 2012 May 03; Vol. 11, pp. 29. Date of Electronic Publication: 2012 May 03.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Cell Adhesion Molecules/*genetics
Cell Transformation, Neoplastic/*genetics
Immunoglobulins/*genetics
Animals ; Cell Adhesion Molecule-1 ; Gene Expression Regulation, Neoplastic ; Genomic Instability ; Mice ; Mice, Knockout ; Micronuclei, Chromosome-Defective ; Mutagenesis, Insertional ; Neoplasms/genetics ; Neoplasms/mortality
Czasopismo naukowe
Tytuł:
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome.
Autorzy:
McIntyre RE; Experimental Cancer Genetics, Wellcome Trust Sanger Institute, Hinxton, United Kingdom.
Lakshminarasimhan Chavali P
Ismail O
Carragher DM
Sanchez-Andrade G
Forment JV
Fu B
Del Castillo Velasco-Herrera M
Edwards A
van der Weyden L
Yang F
Ramirez-Solis R
Estabel J
Gallagher FA
Logan DW
Arends MJ
Tsang SH
Mahajan VB
Scudamore CL
White JK
Jackson SP
Gergely F
Adams DJ
Pokaż więcej
Corporate Authors:
Sanger Mouse Genetics Project
Źródło:
PLoS genetics [PLoS Genet] 2012; Vol. 8 (11), pp. e1003022. Date of Electronic Publication: 2012 Nov 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Centrioles*/genetics
Centrioles*/metabolism
Dwarfism*/genetics
Dwarfism*/physiopathology
Microcephaly*/genetics
Microcephaly*/physiopathology
Embryonic Development/*genetics
Microtubule-Associated Proteins/*genetics
Animals ; Apoptosis ; DNA Damage ; Facies ; Genomic Instability ; Mice ; Mice, Transgenic ; Microtubule-Associated Proteins/deficiency ; Microtubule-Associated Proteins/metabolism ; Mitosis/genetics ; Mutation ; Signal Transduction/genetics ; Spindle Apparatus/genetics
SCR Disease Name:
Seckel syndrome 1
Czasopismo naukowe
Tytuł:
Mouse genomic variation and its effect on phenotypes and gene regulation.
Autorzy:
Keane TM; The Wellcome Trust Sanger Institute, Hinxton, Cambridge CB10 1HH, UK.
Goodstadt L
Danecek P
White MA
Wong K
Yalcin B
Heger A
Agam A
Slater G
Goodson M
Furlotte NA
Eskin E
Nellåker C
Whitley H
Cleak J
Janowitz D
Hernandez-Pliego P
Edwards A
Belgard TG
Oliver PL
McIntyre RE
Bhomra A
Nicod J
Gan X
Yuan W
van der Weyden L
Steward CA
Bala S
Stalker J
Mott R
Durbin R
Jackson IJ
Czechanski A
Guerra-Assunção JA
Donahue LR
Reinholdt LG
Payseur BA
Ponting CP
Birney E
Flint J
Adams DJ
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Źródło:
Nature [Nature] 2011 Sep 14; Vol. 477 (7364), pp. 289-94. Date of Electronic Publication: 2011 Sep 14.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Phenotype*
Gene Expression Regulation/*genetics
Genetic Variation/*genetics
Genome/*genetics
Mice/*genetics
Mice, Inbred Strains/*genetics
Alleles ; Animals ; Animals, Laboratory/genetics ; Genomics ; Mice/classification ; Mice, Inbred C57BL/genetics ; Phylogeny ; Quantitative Trait Loci/genetics
Czasopismo naukowe
Tytuł:
Disruption of mouse Slx4, a regulator of structure-specific nucleases, phenocopies Fanconi anemia.
Autorzy:
Crossan GP; Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK.
van der Weyden L
Rosado IV
Langevin F
Gaillard PHL
McIntyre RE
Gallagher F
Kettunen MI
Lewis DY
Brindle K
Arends MJ
Adams DJ
Patel KJ
Pokaż więcej
Corporate Authors:
Sanger Mouse Genetics Project
Źródło:
Nature genetics [Nat Genet] 2011 Feb; Vol. 43 (2), pp. 147-52. Date of Electronic Publication: 2011 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Fanconi Anemia/*genetics
Recombinases/*genetics
Recombinases/*physiology
Animals ; Cellular Senescence ; Cross-Linking Reagents/pharmacology ; DNA Damage ; Female ; Fibroblasts/metabolism ; Genetic Complementation Test ; Hematopoietic Stem Cells ; Humans ; Magnetic Resonance Imaging/methods ; Male ; Mice ; Mice, Knockout
Czasopismo naukowe
Tytuł:
The activating mutation R201C in GNAS promotes intestinal tumourigenesis in Apc(Min/+) mice through activation of Wnt and ERK1/2 MAPK pathways.
Autorzy:
Wilson CH; Experimental Cancer Genetics, Wellcome Trust, Sanger Institute, Hinxton, UK.
McIntyre RE
Arends MJ
Adams DJ
Pokaż więcej
Źródło:
Oncogene [Oncogene] 2010 Aug 12; Vol. 29 (32), pp. 4567-75. Date of Electronic Publication: 2010 Jun 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
MAP Kinase Signaling System*
Adenomatous Polyposis Coli Protein/*metabolism
Colorectal Neoplasms/*genetics
Colorectal Neoplasms/*pathology
GTP-Binding Protein alpha Subunits, Gs/*metabolism
Mutant Proteins/*metabolism
Wnt Proteins/*metabolism
Adenoma/enzymology ; Adenoma/genetics ; Adenoma/metabolism ; Adenoma/pathology ; Alleles ; Animals ; Cell Differentiation/genetics ; Cell Proliferation ; Chromogranins ; Colorectal Neoplasms/enzymology ; Colorectal Neoplasms/metabolism ; Cyclic AMP/metabolism ; Disease Progression ; Epithelial Cells/metabolism ; Epithelial Cells/pathology ; Female ; GTP-Binding Protein alpha Subunits, Gs/genetics ; Gene Expression Regulation, Neoplastic ; Genetic Loci/genetics ; Humans ; Intestinal Mucosa/metabolism ; Intestinal Mucosa/pathology ; Male ; Membrane Glycoproteins/genetics ; Mice ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 3/metabolism ; Mutant Proteins/genetics ; Mutation ; Organ Specificity ; Phosphoric Diester Hydrolases/metabolism ; Promoter Regions, Genetic/genetics ; Stem Cells/metabolism ; Stem Cells/pathology ; Substrate Specificity ; Up-Regulation
Czasopismo naukowe
    Wyświetlanie 1-12 z 12

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