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Tytuł :
Prospective experimental treatment of colorectal cancer patients based on organoid drug responses.
Autorzy :
Ooft SN; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Weeber F; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Schipper L; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Dijkstra KK; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
McLean CM; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Kaing S; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
van de Haar J; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands; Department of Molecular Carcinogenesis, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Prevoo W; Department of Radiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Werkhoven E; Department of Biometrics, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Snaebjornsson P; Department of Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Hoes LR; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands.
Chalabi M; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
van der Velden D; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Radiology and Nuclear Medicine, Amsterdam University Medical Center AMC, Amsterdam, The Netherlands.
van Leerdam M; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Boot H; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Grootscholten C; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Huitema ADR; Department of Pharmacy & Pharmacology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Department of Clinical Pharmacy, University Medical Centre Utrecht, Utrecht, The Netherlands.
Bloemendal HJ; Department of Internal Medicine/Oncology, Radboud University Medical Center Nijmegen, Nijmegen, The Netherlands.
Cuppen E; Oncode Institute, Utrecht, The Netherlands; Division of Biomedical Genetics, Centre for Molecular Medicine, University Medical Centre Utrecht, Utrecht, The Netherlands; Hartwig Medical Foundation, Amsterdam, The Netherlands.
Voest EE; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands; Oncode Institute, Utrecht, The Netherlands; Department of Gastrointestinal Oncology, The Netherlands Cancer Institute, Amsterdam, The Netherlands. Electronic address: .
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Źródło :
ESMO open [ESMO Open] 2021 Jun; Vol. 6 (3), pp. 100103. Date of Electronic Publication: 2021 Apr 19.
Typ publikacji :
Journal Article
Czasopismo naukowe
Tytuł :
Evidence based care for pregnant women with covid-19.
Autorzy :
Pirkle CM; Office of Public Health Studies, University of Hawaii at Manoa, Honolulu, HI, USA.
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Źródło :
BMJ (Clinical research ed.) [BMJ] 2020 Sep 09; Vol. 370, pp. m3510. Date of Electronic Publication: 2020 Sep 09.
Typ publikacji :
Editorial; Comment
MeSH Terms :
Coronavirus*
Coronavirus Infections*
Pandemics*
Pneumonia, Viral*
Pregnancy Complications, Infectious*
Betacoronavirus ; COVID-19 ; Evidence-Based Medicine ; Female ; Humans ; Pregnancy ; Risk Factors ; SARS-CoV-2
Opinia redakcyjna
Tytuł :
Growth of Non-Halophilic Bacteria in the Sodium-Magnesium-Sulfate-Chloride Ion System: Unravelling the Complexities of Ion Interactions in Terrestrial and Extraterrestrial Aqueous Environments.
Autorzy :
Cockell CS; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
McLean CM; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Perera L; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Aka S; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Stevens A; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Dickinson AW; UK Centre for Astrobiology, School of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
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Źródło :
Astrobiology [Astrobiology] 2020 Aug; Vol. 20 (8), pp. 944-955. Date of Electronic Publication: 2020 May 20.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adaptation, Physiological*
Water Microbiology*
Bacteria/*growth & development
Extraterrestrial Environment/*chemistry
Water/*chemistry
Chlorides/chemistry ; Earth, Planet ; Exobiology ; Ions/chemistry ; Magnesium/chemistry ; Osmolar Concentration ; Sodium/chemistry ; Sulfates/chemistry
Czasopismo naukowe
Tytuł :
Rapeseed-based diet modulates the imputed functions of gut microbiome in growing-finishing pigs.
Autorzy :
Umu ÖCO; Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.O. Box 369, N-0102, Oslo, Norway. .
Mydland LT; Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, P.O. Box 5003, N-1432, Ås, Norway.
Øverland M; Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, P.O. Box 5003, N-1432, Ås, Norway.
Press CM; Department of Preclinical Sciences and Pathology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.O. Box 369, N-0102, Oslo, Norway.
Sørum H; Department of Paraclinical Sciences, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, P.O. Box 369, N-0102, Oslo, Norway.
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Źródło :
Scientific reports [Sci Rep] 2020 Jun 10; Vol. 10 (1), pp. 9372. Date of Electronic Publication: 2020 Jun 10.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animal Feed/*microbiology
Brassica napus/*metabolism
Clostridiales/*physiology
Gastrointestinal Microbiome/*genetics
Ileum/*microbiology
Intestine, Large/*microbiology
RNA, Ribosomal, 16S/*genetics
Swine/*physiology
Animals ; Bacteria ; Diet ; Energy Metabolism ; Norway ; Soybeans/metabolism
SCR Organism :
Mucispirillum schaedleri
Czasopismo naukowe
Tytuł :
Encouraging Adults to Choose Healthy Now: A Hawai'i Convenience Store Intervention.
Autorzy :
Beckelman T; Hawai'i State Department of Health, Honolulu, HI.
Sinclair-White BM; Hawai'i State Department of Health, Honolulu, HI.
McGurk MD; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, HI.
Donohoe-Mather C; Hawai'i State Department of Health, Honolulu, HI.
Vu U; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, HI.
Ching LK; Hawai'i State Department of Health, Honolulu, HI.
Pirkle CM; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, HI.
Sentell TL; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, HI.
Keliikoa LB; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, HI. Electronic address: .
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Źródło :
Journal of nutrition education and behavior [J Nutr Educ Behav] 2020 Mar; Vol. 52 (3), pp. 330-334. Date of Electronic Publication: 2020 Jan 03.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Commerce*
Diet, Healthy*
Advertising/*methods
Health Promotion/*methods
Behavioral Risk Factor Surveillance System ; Food Supply ; Hawaii ; Humans ; Mass Media
Czasopismo naukowe
Tytuł :
BTK inhibitors synergise with 5-FU to treat drug-resistant TP53-null colon cancers.
Autorzy :
Lavitrano M; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Ianzano L; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Bonomo S; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Cialdella A; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Cerrito MG; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Pisano F; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Missaglia C; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Giovannoni R; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Romano G; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
McLean CM; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
Voest EE; Department of Molecular Oncology and Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.
D'Amato F; NEF-Laboratory, Department of Biomedical Science, University of Cagliari, Cagliari, Italy.
Noli B; NEF-Laboratory, Department of Biomedical Science, University of Cagliari, Cagliari, Italy.
Ferri GL; NEF-Laboratory, Department of Biomedical Science, University of Cagliari, Cagliari, Italy.
Agostini M; First Surgical Clinic Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.; Department of Nanomedicine, The Methodist Hospital Research Institute, Houston, TX, USA.
Pucciarelli S; First Surgical Clinic Section, Department of Surgery, Oncology and Gastroenterology, University of Padova, Padova, Italy.
Helin K; Center for Epigenetics, Sloan Kettering Institute, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
Leone BE; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
Canzonieri V; Pathology Unit and CRO Biobank, CRO Aviano National Cancer Institute, Aviano, Italy.
Grassilli E; School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.
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Źródło :
The Journal of pathology [J Pathol] 2020 Feb; Vol. 250 (2), pp. 134-147. Date of Electronic Publication: 2019 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
Colonic Neoplasms/*drug therapy
Protein Kinase Inhibitors/*administration & dosage
Agammaglobulinaemia Tyrosine Kinase/antagonists & inhibitors ; Agammaglobulinaemia Tyrosine Kinase/metabolism ; Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis/drug effects ; Colonic Neoplasms/genetics ; Colonic Neoplasms/pathology ; Disease Progression ; Drug Resistance, Neoplasm/drug effects ; Drug Synergism ; E2F Transcription Factors/metabolism ; Fluorouracil/administration & dosage ; Fluorouracil/pharmacology ; Genes, p53 ; Humans ; Mice, Nude ; Molecular Targeted Therapy/methods ; Neoplasm Staging ; Organoids/drug effects ; Protein Isoforms/antagonists & inhibitors ; Protein Isoforms/metabolism ; Protein Kinase Inhibitors/pharmacology ; Transforming Growth Factor beta1/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays/methods
Czasopismo naukowe
Tytuł :
Candida utilis yeast as a functional protein source for Atlantic salmon (Salmo salar L.): Local intestinal tissue and plasma proteome responses.
Autorzy :
Reveco-Urzua FE; Department of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
Hofossæter M; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Rao Kovi M; Department of Plant Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
Mydland LT; Department of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
Ånestad R; Department of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
Sørby R; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Press CM; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Lagos L; Department of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
Øverland M; Department of Animal and Aquaculture Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Aas, Norway.
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Źródło :
PloS one [PLoS One] 2019 Dec 30; Vol. 14 (12), pp. e0218360. Date of Electronic Publication: 2019 Dec 30 (Print Publication: 2019).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animal Feed/*microbiology
Candida/*growth & development
Salmo salar/*growth & development
Animal Feed/analysis ; Animal Husbandry/methods ; Animals ; Aquaculture/methods ; Diet ; Gene Expression ; Intestines/physiology ; Proteins ; Proteome/metabolism ; Proteomics ; Soybeans
Czasopismo naukowe
Tytuł :
Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.
Autorzy :
Ooft SN; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Weeber F; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Dijkstra KK; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
McLean CM; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Kaing S; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
van Werkhoven E; Department of Biometrics, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Schipper L; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Hoes L; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Vis DJ; Oncode Institute, 3521 AL Utrecht, Netherlands.; Department of Molecular Carcinogenesis, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van de Haar J; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.; Department of Molecular Carcinogenesis, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Prevoo W; Department of Radiology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Snaebjornsson P; Department of Pathology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van der Velden D; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Klein M; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Oncode Institute, 3521 AL Utrecht, Netherlands.
Chalabi M; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Boot H; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
van Leerdam M; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
Bloemendal HJ; Department of Internal Medicine/Oncology, Radboud University Medical Center Nijmegen, 6525 GA Nijmegen, Netherlands.
Beerepoot LV; Department of Internal Medicine, Elisabeth-TweeSteden Hospital, 5042 AD Tilburg, Netherlands.
Wessels L; Oncode Institute, 3521 AL Utrecht, Netherlands.; Department of Molecular Carcinogenesis, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.; Faculty of Electrical Engineering, Mathematics and Computer Science, Delft University of Technology, 2628 CD Delft, Netherlands.
Cuppen E; Oncode Institute, 3521 AL Utrecht, Netherlands.; Division Biomedical Genetics, Centre for Molecular Medicine, University Medical Centre Utrecht, 3584 CX Utrecht, Netherlands.; Hartwig Medical Foundation, 1098 XH Amsterdam, Netherlands.
Clevers H; Oncode Institute, 3521 AL Utrecht, Netherlands.; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, 3584 CT Utrecht, Netherlands.; Princess Máxima Center for Pediatric Oncology, 3584 CS Utrecht, Netherlands.
Voest EE; Department of Molecular Oncology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands. .; Oncode Institute, 3521 AL Utrecht, Netherlands.; Department of Gastrointestinal Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands.
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Źródło :
Science translational medicine [Sci Transl Med] 2019 Oct 09; Vol. 11 (513).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Colorectal Neoplasms/*metabolism
Colorectal Neoplasms/*pathology
Organoids/*cytology
Antineoplastic Agents/therapeutic use ; Capecitabine/therapeutic use ; Colorectal Neoplasms/drug therapy ; Female ; Fluorouracil/therapeutic use ; Humans ; Irinotecan/therapeutic use ; Oxaliplatin/therapeutic use ; Prospective Studies ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
Autorzy :
Vlaming H; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
McLean CM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Korthout T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Alemdehy MF; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Hendriks S; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Lancini C; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Palit S; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Klarenbeek S; Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Kwesi-Maliepaard EM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Molenaar TM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Hoekman L; Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Schmidlin TT; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute for Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands.
Altelaar AM; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute for Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands.; Proteomics Facility, Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Welsem T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Dannenberg JH; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jacobs H; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
van Leeuwen F; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.
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Źródło :
The EMBO journal [EMBO J] 2019 Jul 15; Vol. 38 (14), pp. e101564. Date of Electronic Publication: 2019 Jun 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Histone Deacetylase 1/*genetics
Histone Deacetylase 2/*metabolism
Histone-Lysine N-Methyltransferase/*genetics
Histones/*metabolism
Lymphoma/*metabolism
Thymus Neoplasms/*metabolism
Acetylation ; Animals ; Cell Line, Tumor ; Gene Deletion ; Histone Deacetylases/genetics ; Humans ; Lymphoma/genetics ; Methylation ; Mice ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Thymus Neoplasms/genetics
Czasopismo naukowe
Tytuł :
Symptoms of urinary incontinence and pelvic organ prolapse and physical performance in middle-aged women from Northeast Brazil: a cross-sectional study.
Autorzy :
Vieira MCA; Physiotherapy Department of Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, S/N Caixa Postal 1524 - Campus Universitário - Lagoa Nova, CEP, Natal, RN, 59072-970, Brazil. .
da Câmara SMA; Physiotherapy Department of Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, S/N Caixa Postal 1524 - Campus Universitário - Lagoa Nova, CEP, Natal, RN, 59072-970, Brazil.
Moreira MA; Federal University of Ceará, Fortaleza, CE, Brazil.
Pirkle CM; University of Hawai'i at Mānoa, Honolulu, HI, USA.
Vafaei A; Lakehead University, Thunder Bay, Ontario, Canada.
Maciel ÁCC; Physiotherapy Department of Federal University of Rio Grande do Norte, Avenida Senador Salgado Filho, S/N Caixa Postal 1524 - Campus Universitário - Lagoa Nova, CEP, Natal, RN, 59072-970, Brazil.
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Źródło :
BMC women's health [BMC Womens Health] 2019 Jul 11; Vol. 19 (1), pp. 94. Date of Electronic Publication: 2019 Jul 11.
Typ publikacji :
Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Physical Functional Performance*
Pelvic Organ Prolapse/*physiopathology
Urinary Incontinence/*physiopathology
Adult ; Aged ; Brazil ; Cross-Sectional Studies ; Female ; Humans ; Linear Models ; Middle Aged ; Parity ; Pelvic Organ Prolapse/etiology ; Pregnancy ; Urinary Incontinence/etiology
Czasopismo naukowe
Tytuł :
Insights in Public Health: Trapped in a Sea of Uncertainty: Limitations in Unintentional Injury Research in the Philippines and Interdisciplinary Solutions to Reduce Fatal Box Jellyfish Stings.
Autorzy :
Pirkle CM; Office of Public Health Studies, Myron B. Thompson School of Social Work, University of Hawai'i at Manoa, Honolulu, HI (CMP).
Yanagihara AA; Pacific Cnidaria Research Laboratory, Pacific Biosciences Research Center, University of Hawai'i at Manoa, Honolulu, HI; Department of Tropical Medicine, Medical Microbiology and Pharmacology, John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, HI (AAY).
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Źródło :
Hawai'i journal of medicine & public health : a journal of Asia Pacific Medicine & Public Health [Hawaii J Med Public Health] 2019 Jan; Vol. 78 (1), pp. 30-34.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Cubozoa*
Accidental Injuries/*epidemiology
Biomedical Research/*standards
Bites and Stings/*epidemiology
Adult ; Animals ; Child ; Female ; Global Health ; Humans ; Male ; Philippines/epidemiology ; Public Health ; Uncertainty
Czasopismo naukowe
Tytuł :
Gut microbiota profiling in Norwegian weaner pigs reveals potentially beneficial effects of a high-fiber rapeseed diet.
Autorzy :
Onarman Umu ÖC; Department of Food Safety and Infection Biology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Fauske AK; Department of Food Safety and Infection Biology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Åkesson CP; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Pérez de Nanclares M; Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Sørby R; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Press CM; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
Øverland M; Department of Animal and Aquacultural Sciences, Faculty of Biosciences, Norwegian University of Life Sciences, Ås, Norway.
Sørum H; Department of Food Safety and Infection Biology, Faculty of Veterinary Medicine, Norwegian University of Life Sciences, Oslo, Norway.
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Źródło :
PloS one [PLoS One] 2018 Dec 20; Vol. 13 (12), pp. e0209439. Date of Electronic Publication: 2018 Dec 20 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Animal Feed*
Gastrointestinal Microbiome*
Brassica rapa/*chemistry
Dietary Fiber/*administration & dosage
Sus scrofa/*microbiology
Animal Husbandry/methods ; Animals ; Hordeum/chemistry ; Ileum/microbiology ; Male ; Soybeans/chemistry ; Swine ; Triticum/chemistry ; Weaning
Czasopismo naukowe
Tytuł :
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
Autorzy :
Antonova-Koch Y; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Meister S; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Abraham M; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Luth MR; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Ottilie S; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Lukens AK; Harvard T. H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA.
Sakata-Kato T; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA.
Vanaerschot M; Division of Infectious Diseases, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.
Owen E; Department of Biochemistry and Molecular Biology and Center for Malaria Research, Pennsylvania State University, University Park, PA 16802, USA.
Jado JC; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Maher SP; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA.
Calla J; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Plouffe D; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Zhong Y; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Chen K; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Chaumeau V; Shoklo Malaria Research Unit, Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Conway AJ; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA.
McNamara CW; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Ibanez M; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Gagaring K; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Serrano FN; Tres Cantos Medicines Development Campus, Malaria DPU, GlaxoSmithKline, Severo Ochoa 2, Tres Cantos 28760, Madrid, Spain.
Eribez K; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Taggard CM; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Cheung AL; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Lincoln C; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Ambachew B; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA.
Rouillier M; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland.
Siegel D; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive 0741, La Jolla, CA 92093, USA.
Nosten F; Shoklo Malaria Research Unit, Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Mae Sot, Thailand.; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Kyle DE; Center for Tropical and Emerging Global Diseases, University of Georgia, 500 D. W. Brooks Drive, Athens, GA 30602, USA.; Department of Global Health, University of South Florida, 3720 Spectrum Boulevard, Tampa, FL 33612, USA.
Gamo FJ; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland.
Zhou Y; The Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA.
Llinás M; Department of Biochemistry and Molecular Biology and Center for Malaria Research, Pennsylvania State University, University Park, PA 16802, USA.; Department of Chemistry and Center for Infectious Diseases Dynamics, Pennsylvania State University, University Park, PA 16802, USA.
Fidock DA; Division of Infectious Diseases, Department of Microbiology and Immunology, Columbia University Medical Center, New York, NY 10032, USA.
Wirth DF; Harvard T. H. Chan School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA.; The Broad Institute, 415 Main Street, Cambridge, MA 02142, USA.
Burrows J; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland.
Campo B; Medicines for Malaria Venture, Post Office Box 1826, 20 Route de Pre-Bois, 1215 Geneva 15, Switzerland.
Winzeler EA; School of Medicine, University of California, San Diego, 9500 Gilman Drive 0760, La Jolla, CA 92093, USA. .; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive 0741, La Jolla, CA 92093, USA.
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Źródło :
Science (New York, N.Y.) [Science] 2018 Dec 07; Vol. 362 (6419).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chemoprevention*
Drug Discovery*
Antimalarials/*pharmacology
Malaria/*prevention & control
Plasmodium/*drug effects
Antimalarials/chemistry ; Antimalarials/isolation & purification ; Antimalarials/therapeutic use ; Drug Evaluation, Preclinical ; Humans ; Mitochondria/drug effects ; Plasmodium/growth & development
Czasopismo naukowe
Tytuł :
Relationship between maximal respiratory pressures and multiple childbearing in Brazilian middle-aged and older women: A cross-sectional community-based study.
Autorzy :
Azevedo IG; Physiotherapy Department, Universidade Federal do Rio Grande do Norte, Natal Rio Grande do Norte, Brazil.
da Câmara SMA; Faculdade de Ciências da Saúde do Trairi, Universidade Federal do Rio Grande do Norte, Santa Cruz, Rio Grande do Norte, Brazil.
Pirkle CM; Office of Public Health Studies, University of Hawai'i at Mānoa, Honolulu, Hawai'i, United States of America.
Maciel ÁCC; Physiotherapy Department, Universidade Federal do Rio Grande do Norte, Natal Rio Grande do Norte, Brazil.
Viana ESR; Physiotherapy Department, Universidade Federal do Rio Grande do Norte, Natal Rio Grande do Norte, Brazil.
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Źródło :
PloS one [PLoS One] 2018 Dec 04; Vol. 13 (12), pp. e0208500. Date of Electronic Publication: 2018 Dec 04 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Maximal Respiratory Pressures*
Parity/*physiology
Respiratory Muscles/*physiology
Adult ; Aged ; Aged, 80 and over ; Brazil/epidemiology ; Cross-Sectional Studies ; Female ; Humans ; Middle Aged ; Muscle Strength/physiology ; Pregnancy ; Reproductive History ; Residence Characteristics
Czasopismo naukowe
Tytuł :
Frailty and life course violence: The international mobility in aging study.
Autorzy :
Dos Santos Gomes C; Department of Physioterapy, Federal University of Rio Grande Do Norte, Avenida Senador Salgado Filho, 3000, Lagoa Nova, Natal, RN, 59064-741, Brazil. Electronic address: .
Pirkle CM; Office of Public Health Studies, University of Hawaii, 2500 Campus Rd., Honolulu, HI 96822, United States.
Zunzunegui MV; Department of Social Medicine, Montreal University, 2900 Boulevard Edouard-Montpetit, Montréal, QC, H3T 1J4, Canada.
Taurino Guedes D; Department of Physioterapy, Faculty of Health Sciences of Trairí, Federal University of Rio Grande Do Norte, R. Teodorico Bezerra, 2-122, Santa Cruz, RN, 59200-000, Brazil.
Fernandes De Souza Barbosa J; Department of Physioterapy, Federal University of Rio Grande Do Norte, Avenida Senador Salgado Filho, 3000, Lagoa Nova, Natal, RN, 59064-741, Brazil.
Hwang P; Department of Social Medicine, Montreal University, 2900 Boulevard Edouard-Montpetit, Montréal, QC, H3T 1J4, Canada.
Oliveira Guerra R; Department of Physioterapy, Federal University of Rio Grande Do Norte, Avenida Senador Salgado Filho, 3000, Lagoa Nova, Natal, RN, 59064-741, Brazil.
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Źródło :
Archives of gerontology and geriatrics [Arch Gerontol Geriatr] 2018 May - Jun; Vol. 76, pp. 26-33. Date of Electronic Publication: 2018 Feb 08.
Typ publikacji :
Journal Article; Multicenter Study
MeSH Terms :
Aging*
Interpersonal Relations*
Chronic Disease/*epidemiology
Domestic Violence/*statistics & numerical data
Frailty/*epidemiology
Aged ; Brazil/epidemiology ; Cross-Sectional Studies ; Female ; Global Health ; Humans ; Male ; Middle Aged ; Prevalence ; Sex Factors
Czasopismo naukowe
Tytuł :
Fatty acid 16:4(n-3) stimulates a GPR120-induced signaling cascade in splenic macrophages to promote chemotherapy resistance.
Autorzy :
Houthuijzen JM; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Molecular Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Oosterom I; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
Hudson BD; Centre for Translational Pharmacology, Institute of Molecular, Cell, and Systems Biology, University of Glasgow, Glasgow, United Kingdom.
Hirasawa A; Department of Genomic Drug Discovery Science, Kyoto University, Kyoto, Japan.
Daenen LGM; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
McLean CM; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Hansen SVF; Department of Physics, Chemistry, and Pharmacy, University of Southern Denmark, Odense, Denmark.
van Jaarsveld MTM; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Peeper DS; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Jafari Sadatmand S; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
Roodhart JML; Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands.
van de Lest CHA; Department of Biochemistry and Cell Biology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.
Ulven T; Department of Physics, Chemistry, and Pharmacy, University of Southern Denmark, Odense, Denmark.
Ishihara K; National Research Institute of Fisheries Science, Kanazawaku, Japan.
Milligan G; Centre for Translational Pharmacology, Institute of Molecular, Cell, and Systems Biology, University of Glasgow, Glasgow, United Kingdom.
Voest EE; Department of Molecular Oncology, Netherlands Cancer Institute, Amsterdam, The Netherlands.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2017 May; Vol. 31 (5), pp. 2195-2209. Date of Electronic Publication: 2017 Feb 09.
Typ publikacji :
Journal Article
MeSH Terms :
Signal Transduction*/physiology
Macrophages/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Animals ; Drug Resistance/physiology ; Fatty Acids, Omega-3/metabolism ; Mice, Inbred BALB C
Czasopismo naukowe
Tytuł :
Morphological and functional development of the interbranchial lymphoid tissue (ILT) in Atlantic salmon (Salmo salar L).
Autorzy :
Dalum AS; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway. Electronic address: .
Griffiths DJ; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Valen EC; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Amthor KS; LetSea Helgeland Havbruksstasjon AS, Sandnessjøen, Norway.
Austbø L; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Koppang EO; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Press CM; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
Kvellestad A; Department of Basic Sciences and Aquatic Medicine, Faculty of Veterinary Medicine and Biosciences, Norwegian University of Life Sciences, Oslo, Norway.
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Źródło :
Fish & shellfish immunology [Fish Shellfish Immunol] 2016 Nov; Vol. 58, pp. 153-164. Date of Electronic Publication: 2016 Sep 12.
Typ publikacji :
Journal Article
MeSH Terms :
Lymphoid Tissue/*cytology
Lymphoid Tissue/*growth & development
Salmo salar/*anatomy & histology
Salmo salar/*growth & development
Animals ; Female ; Gills/cytology ; Gills/growth & development ; Gills/metabolism ; Male ; Salmo salar/genetics ; Salmo salar/metabolism ; Thymus Gland/cytology ; Thymus Gland/growth & development
Czasopismo naukowe
Tytuł :
Managing mercury exposure in northern Canadian communities.
Autorzy :
Pirkle CM; Office of Public Health Studies (Pirkle), University of Hawaii at Manoa, Honolulu; École de psychologie (Muckle), Université Laval, Laval, Que.; Axe santé des populations et pratiques optimales en santé (Lemire, Muckle), Centre de recherche du CHU de Québec, Québec, Que. .
Muckle G; Office of Public Health Studies (Pirkle), University of Hawaii at Manoa, Honolulu; École de psychologie (Muckle), Université Laval, Laval, Que.; Axe santé des populations et pratiques optimales en santé (Lemire, Muckle), Centre de recherche du CHU de Québec, Québec, Que.
Lemire M; Office of Public Health Studies (Pirkle), University of Hawaii at Manoa, Honolulu; École de psychologie (Muckle), Université Laval, Laval, Que.; Axe santé des populations et pratiques optimales en santé (Lemire, Muckle), Centre de recherche du CHU de Québec, Québec, Que.
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Źródło :
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne [CMAJ] 2016 Oct 04; Vol. 188 (14), pp. 1015-1023. Date of Electronic Publication: 2016 Jul 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Counseling*
Nutrition Policy*
Environmental Exposure/*prevention & control
Mercury Poisoning/*prevention & control
Animals ; Canada ; Diet ; Fishes ; Food Supply ; Health Promotion ; Humans ; Indians, North American ; Mass Screening ; Mercury/adverse effects ; Mercury/blood ; Mercury Poisoning/diagnosis ; Mercury Poisoning/physiopathology ; Prenatal Care
Czasopismo naukowe
Tytuł :
Imprinted DNA methylation reconstituted at a non-imprinted locus.
Autorzy :
Taylor DH; Field of Genetics, Genomics, and Development, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA.
McLean CM; Field of Genetics, Genomics, and Development, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA ; Department of Molecular Oncology, The Netherlands Cancer Institute, Plesmanlaan, Amsterdam, The Netherlands.
Wu WL; Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA.
Wang AB; Field of Biochemistry, Molecular and Cell Biology, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA.
Soloway PD; Field of Genetics, Genomics, and Development, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA ; Division of Nutritional Sciences, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA ; Field of Biochemistry, Molecular and Cell Biology, College of Agriculture and Life Sciences, Cornell University, Ithaca, NY USA.
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Źródło :
Epigenetics & chromatin [Epigenetics Chromatin] 2016 Sep 22; Vol. 9, pp. 41. Date of Electronic Publication: 2016 Sep 22 (Print Publication: 2016).
Typ publikacji :
Journal Article
Czasopismo naukowe

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