- Tytuł:
- Whole-genome analysis informs breast cancer response to aromatase inhibition.
- Autorzy:
- Źródło:
- Nature [Nature] 2012 Jun 10; Vol. 486 (7403), pp. 353-60. Date of Electronic Publication: 2012 Jun 10.
- Typ publikacji:
- Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
- MeSH Terms:
-
Aromatase/*metabolism
Aromatase Inhibitors/*therapeutic useBreast Neoplasms /*drug therapyBreast Neoplasms /*genetics
Genome, Human/*genetics
Anastrozole ; Androstadienes/pharmacology ; Androstadienes/therapeutic use ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ;Breast Neoplasms /metabolism ;Breast Neoplasms /pathology ; DNA Repair ; Exome/genetics ; Exons/genetics ; Female ; Genetic Variation/genetics ; Humans ; Letrozole ; MAP Kinase Kinase 4/genetics ; MAP Kinase Kinase Kinase 1/genetics ; Mutation/genetics ; Nitriles/pharmacology ; Nitriles/therapeutic use ; Receptors, Estrogen/metabolism ; Treatment Outcome ; Triazoles/pharmacology ; Triazoles/therapeutic use
Czasopismo naukowe