Autor: "McNamara LM" - OpacWWW

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Tytuł:: Constructing validity evidence from a pilot key-features assessment of clinical decision-making in cerebral palsy diagnosis: application of Kane’s validity framework to implementation evaluations
Autorzy:: McNamara, LMAff1, IDs12909023046314_cor1
Scott, KM
Boyd, RN
Farmer, EA
Webb, AE
Novak, IE; Pokaż więcej
Źródło:: BMC Medical Education. 23(1)

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Tytuł:: Estrogen withdrawal alters cytoskeletal and primary ciliary dynamics resulting in increased Hedgehog and osteoclastogenic paracrine signalling in osteocytes.
Autorzy:: Geoghegan IP; Mechanobiology and Medical Devices Research Group, Biomedical Engineering, College of Science and Engineering, National University of Ireland, Galway, Ireland.; Centre for Research in Medical Devices (CÚRAM), National University of Ireland, Galway, Ireland.
McNamara LM; Mechanobiology and Medical Devices Research Group, Biomedical Engineering, College of Science and Engineering, National University of Ireland, Galway, Ireland.; Centre for Research in Medical Devices (CÚRAM), National University of Ireland, Galway, Ireland.
Hoey DA; Centre for Research in Medical Devices (CÚRAM), National University of Ireland, Galway, Ireland. .; Trinity Centre for Biomedical Engineering, Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, D02 R590, Ireland. .; Department of Mechanical, Manufacturing, and Biomedical Engineering, School of Engineering, Trinity College Dublin, Dublin, Ireland. .; Advanced Materials and Bioengineering Research Centre, Trinity College Dublin & RCSI, Dublin 2, Ireland. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2021 Apr 29; Vol. 11 (1), pp. 9272. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cilia/*physiology
Estrogens/*deficiency
Hedgehog Proteins/*metabolism
Osteocytes/*metabolism
Osteogenesis/*physiology
Animals ; Mice ; Osteocytes/cytology ; Paracrine Communication

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Skocz do pozycji: 4.

Tytuł:: Scl-Ab reverts pro-osteoclastogenic signalling and resorption in estrogen deficient osteocytes.
Autorzy:: Allison H; Mechanobiology and Medical Devices Research Group (MMDRG), Centre for Biomechanics Research (BioMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway, Ireland.
Holdsworth G; Early Solutions, UCB Pharma, Slough, UK.
McNamara LM; Mechanobiology and Medical Devices Research Group (MMDRG), Centre for Biomechanics Research (BioMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway, Ireland. laoise.mcnamara@nuigalway.ie.; Pokaż więcej
Źródło:: BMC molecular and cell biology [BMC Mol Cell Biol] 2020 Nov 04; Vol. 21 (1), pp. 78. Date of Electronic Publication: 2020 Nov 04.
Typ publikacji:: Journal Article
MeSH Terms:: Adaptor Proteins, Signal Transducing/*antagonists & inhibitors
Estrogens/*deficiency
Osteocytes/*drug effects
Osteocytes/*metabolism
Osteogenesis/*drug effects
Signal Transduction/*drug effects
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/metabolism ; Animals ; Antibodies, Neutralizing/pharmacology ; Bone Resorption/metabolism ; CCN Intercellular Signaling Proteins/genetics ; CCN Intercellular Signaling Proteins/metabolism ; Cathepsin K/genetics ; Cathepsin K/metabolism ; Chemokine CXCL12/genetics ; Chemokine CXCL12/metabolism ; Coculture Techniques ; Culture Media, Conditioned/pharmacology ; Estrogens/pharmacology ; Female ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/genetics ; Intracellular Signaling Peptides and Proteins/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice ; Mice, Inbred C57BL ; NFATC Transcription Factors/genetics ; NFATC Transcription Factors/metabolism ; Osteoprotegerin/genetics ; Osteoprotegerin/metabolism ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; RANK Ligand/genetics ; RANK Ligand/metabolism ; Signal Transduction/genetics ; Up-Regulation ; Wnt Proteins/antagonists & inhibitors

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Skocz do pozycji: 5.

Tytuł:: Administration of Human Non-Diabetic Mesenchymal Stromal Cells to a Murine Model of Diabetic Fracture Repair: A Pilot Study.
Autorzy:: Watson L; Orbsen Therapeutics Ltd, Galway City H91 EFD0, County Galway, Ireland.
Chen XZ; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.
Ryan AE; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.; CÚRAM Centre for Research in Medical Devices, College of Medicine, Nursing and Health Sciences, School of Medicine, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.
Fleming Á; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.
Carbin A; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.
O'Flynn L; Orbsen Therapeutics Ltd, Galway City H91 EFD0, County Galway, Ireland.
Loftus PG; Orbsen Therapeutics Ltd, Galway City H91 EFD0, County Galway, Ireland.
Horan E; Orbsen Therapeutics Ltd, Galway City H91 EFD0, County Galway, Ireland.
Connolly D; Biomedical Engineering, College of Science and Engineering, National University of Ireland Galway, Galway City H91 HX31, County Galway, Ireland.
McDonnell P; Biomedical Engineering, College of Science and Engineering, National University of Ireland Galway, Galway City H91 HX31, County Galway, Ireland.
McNamara LM; CÚRAM Centre for Research in Medical Devices, College of Medicine, Nursing and Health Sciences, School of Medicine, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.; Biomedical Engineering, College of Science and Engineering, National University of Ireland Galway, Galway City H91 HX31, County Galway, Ireland.
O'Brien T; Orbsen Therapeutics Ltd, Galway City H91 EFD0, County Galway, Ireland.; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.; CÚRAM Centre for Research in Medical Devices, College of Medicine, Nursing and Health Sciences, School of Medicine, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.
Coleman CM; College of Medicine, Nursing and Health Sciences, School of Medicine, Regenerative Medicine Institute, National University of Ireland Galway, Galway City H91 W2TY, County Galway, Ireland.; Pokaż więcej
Źródło:: Cells [Cells] 2020 Jun 03; Vol. 9 (6). Date of Electronic Publication: 2020 Jun 03.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Fracture Healing*
Mesenchymal Stem Cell Transplantation*
Diabetes Mellitus, Experimental/*pathology
Diabetes Mellitus, Experimental/*therapy
Mesenchymal Stem Cells/*cytology
Adult ; Animals ; Bone Marrow Cells/cytology ; Disease Models, Animal ; Humans ; Lymphocytes/cytology ; Male ; Mice, Inbred C57BL ; Pilot Projects

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Skocz do pozycji: 6.

Tytuł:: Risk Factors for Problem Gambling in California: Demographics, Comorbidities and Gambling Participation.
Autorzy:: Volberg RA; School of Public Health and Health Sciences, University of Massachusetts Amherst, 715 N. Pleasant Street, Amherst, MA, 01003, USA. .
McNamara LM; NORC at the University of Chicago, 55 East Monroe Street, Chicago, IL, 60603, USA.
Carris KL; NORC at the University of Chicago, 55 East Monroe Street, Chicago, IL, 60603, USA.; Pokaż więcej
Źródło:: Journal of gambling studies [J Gambl Stud] 2018 Jun; Vol. 34 (2), pp. 361-377.
Typ publikacji:: Journal Article
MeSH Terms:: Behavior, Addictive/*epidemiology
Gambling/*epidemiology
Adolescent ; Adult ; Age Distribution ; Aged ; Behavior, Addictive/psychology ; California/epidemiology ; Comorbidity ; Cross-Sectional Studies ; Ethnicity ; Female ; Gambling/psychology ; Humans ; Male ; Middle Aged ; Prevalence ; Risk Factors ; Sex Distribution ; Surveys and Questionnaires ; Young Adult

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Skocz do pozycji: 7.

Tytuł:: Effects of in vitro endochondral priming and pre-vascularisation of human MSC cellular aggregates in vivo.
Autorzy:: Freeman FE; Centre for Biomechanics Research (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway, Ireland. .
Allen AB; Wallace H. Coulter Department of Biomedical Engineering, Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, 315 Ferst Drive NW, Atlanta, GA, 30332, USA. .
Stevens HY; George W. Woodruff School of Mechanical Engineering, Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, 315 Ferst Drive NW, Atlanta, GA, 30332, USA. .
Guldberg RE; George W. Woodruff School of Mechanical Engineering, Parker H. Petit Institute for Bioengineering & Bioscience, Georgia Institute of Technology, 315 Ferst Drive NW, Atlanta, GA, 30332, USA. .
McNamara LM; Centre for Biomechanics Research (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland Galway, Galway, Ireland. laoise.mcnamara@nuigalway.ie.; Pokaż więcej
Źródło:: Stem cell research & therapy [Stem Cell Res Ther] 2015 Nov 05; Vol. 6, pp. 218. Date of Electronic Publication: 2015 Nov 05.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Neovascularization, Physiologic*
Osteogenesis*
Mesenchymal Stem Cells/*cytology
Animals ; Bone Regeneration ; Calcification, Physiologic ; Cell Aggregation ; Chondrogenesis ; Coculture Techniques ; Human Umbilical Vein Endothelial Cells/cytology ; Humans ; In Vitro Techniques ; Male ; Mesenchymal Stem Cell Transplantation ; Rats ; Rats, Nude ; Tissue Engineering ; Young Adult

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Skocz do pozycji: 8.

Tytuł:: Thermally induced osteocyte damage initiates a remodelling signaling cascade.
Autorzy:: Dolan EB; Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland; National Centre for Biomedical Engineering Science (NCBES), National University of Ireland, Galway, Ireland.
Haugh MG; Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland; National Centre for Biomedical Engineering Science (NCBES), National University of Ireland, Galway, Ireland.
Voisin MC; Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland; National Centre for Biomedical Engineering Science (NCBES), National University of Ireland, Galway, Ireland.
Tallon D; Stryker Ireland, Carrigtwohill, Cork, Ireland.
McNamara LM; Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland; National Centre for Biomedical Engineering Science (NCBES), National University of Ireland, Galway, Ireland.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2015 Mar 18; Vol. 10 (3), pp. e0119652. Date of Electronic Publication: 2015 Mar 18 (Print Publication: 2015).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Hot Temperature*
Bone Remodeling/*physiology
Bone and Bones/*injuries
Orthopedic Procedures/*adverse effects
Osteocytes/*pathology
Signal Transduction/*physiology
Alkaline Phosphatase/metabolism ; Analysis of Variance ; Animals ; Apoptosis/physiology ; Calcium/metabolism ; Flow Cytometry ; Gene Expression Regulation/physiology ; Mice ; Mice, Inbred BALB C ; Microscopy, Fluorescence

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Skocz do pozycji: 9.

Tytuł:: Are all osteocytes equal? Multiscale modelling of cortical bone to characterise the mechanical stimulation of osteocytes.
Autorzy:: Vaughan TJ; Biomechanics Research Centre (BMEC), Biomedical Engineering, College of Engineering and Informatics, National University of Ireland, Galway, Ireland; National Centre for Biomedical Engineering Sciences (NCBES), National University of Ireland, Galway, Ireland.
Verbruggen SW
McNamara LM; Pokaż więcej
Źródło:: International journal for numerical methods in biomedical engineering [Int J Numer Method Biomed Eng] 2013 Dec; Vol. 29 (12), pp. 1361-72. Date of Electronic Publication: 2013 Jul 29.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Computer Simulation*
Models, Biological*
Biomechanical Phenomena/*physiology
Osteocytes/*cytology
Osteocytes/*physiology
Finite Element Analysis ; Humans ; Mechanotransduction, Cellular

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Skocz do pozycji: 10.

Tytuł:: Perforation of cancellous bone trabeculae by damage-stimulated remodelling at resorption pits: a computational analysis.
Autorzy:: McNamara LM; Center for Bioengineeing, Deparment of Mechanical Engineering, Trinity College, Dublin, Ireland.
Prendergast PJ; Pokaż więcej
Źródło:: European journal of morphology [Eur J Morphol] 2005 Feb-Apr; Vol. 42 (1-2), pp. 99-109.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Bone and Bones/*pathology
Algorithms ; Biomechanical Phenomena ; Bone Density ; Bone Marrow Cells/cytology ; Bone Remodeling ; Bone Resorption ; Bone and Bones/anatomy & histology ; Bone and Bones/metabolism ; Computational Biology ; Computer Simulation ; Finite Element Analysis ; Fracture Healing ; Fractures, Stress ; Humans ; Models, Statistical ; Osteoclasts/cytology ; Osteoporosis/pathology ; Software ; Temperature

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