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Title:
TRPM5 activation depends on a synergistic effect of calcium and PKC phosphorylation.
Authors:
Nmarneh A; The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Karem, Jerusalem, 9112102, Israel.
Priel A; The Institute for Drug Research, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Ein Karem, Jerusalem, 9112102, Israel. .
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Source:
Communications biology [Commun Biol] 2024 Mar 27; Vol. 7 (1), pp. 369. Date of Electronic Publication: 2024 Mar 27.
Publication Type:
Journal Article
MeSH Terms:
Calcium*/metabolism
TRPM Cation Channels*/genetics
TRPM Cation Channels*/metabolism
Phosphorylation ; Membrane Potentials ; Calcium Channels/metabolism
Academic Journal
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Title:
Exploring the limitations of mitochondrial dye as a genuine horizontal mitochondrial transfer surrogate.
Authors:
Chen C; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University; Xiamen, Fujian, 361102, China. .
Li H; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University; Xiamen, Fujian, 361102, China.
Zhang J; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University; Xiamen, Fujian, 361102, China.
Cheng SC; State Key Laboratory of Cellular Stress Biology, School of Life Sciences, Faculty of Medicine and Life Sciences, Xiamen University; Xiamen, Fujian, 361102, China. .; Department of Gastroenterology, The National Key Clinical Specialty, Zhongshan Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, China. .; Department of Digestive Disease, School of Medicine, Xiamen University, Xiamen, Fujian, 361004, China. .
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Source:
Communications biology [Commun Biol] 2024 Mar 07; Vol. 7 (1), pp. 281. Date of Electronic Publication: 2024 Mar 07.
Publication Type:
Journal Article
MeSH Terms:
Mitochondria*
Coloring Agents*
Reproducibility of Results ; Cell Membrane ; Membrane Potentials
Academic Journal
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Title:
Solute Transport through Mitochondrial Porins In Vitro and In Vivo.
Authors:
Benz R; Science Faculty, Constructor University Bremen, Campus-Ring 1, 28759 Bremen, Germany.
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Source:
Biomolecules [Biomolecules] 2024 Mar 04; Vol. 14 (3). Date of Electronic Publication: 2024 Mar 04.
Publication Type:
Journal Article; Review
MeSH Terms:
Ion Channels*/metabolism
Voltage-Dependent Anion Channels*/metabolism
Porins/analysis ; Porins/chemistry ; Porins/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondria/metabolism ; Membrane Potentials
Academic Journal
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Title:
Challenges in the Therapeutic Targeting of KCa Channels: From Basic Physiology to Clinical Applications.
Authors:
Van NTH; Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Republic of Korea.; Channelopathy Research Center (CRC), Dongguk University College of Medicine, Goyang 10326, Republic of Korea.
Kim WK; Channelopathy Research Center (CRC), Dongguk University College of Medicine, Goyang 10326, Republic of Korea.; Department of Internal Medicine, Graduate School of Medicine, Dongguk University, Goyang 10326, Republic of Korea.
Nam JH; Department of Physiology, Dongguk University College of Medicine, Gyeongju 38066, Republic of Korea.; Channelopathy Research Center (CRC), Dongguk University College of Medicine, Goyang 10326, Republic of Korea.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2024 Mar 04; Vol. 25 (5). Date of Electronic Publication: 2024 Mar 04.
Publication Type:
Journal Article; Review
MeSH Terms:
Cardiovascular System*/metabolism
Potassium Channels, Calcium-Activated*
Calcium/metabolism ; Membrane Potentials ; Pharmaceutical Preparations ; Humans
Academic Journal
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Title:
Cellular mechanisms underlying carry-over effects after magnetic stimulation.
Authors:
Ye H; Department of Biology, Loyola University Chicago, Quinlan Life Sciences Education and Research Center, 1032 W. Sheridan Rd., Chicago, IL, 60660, USA. .
Dima M; Department of Biology, Loyola University Chicago, Quinlan Life Sciences Education and Research Center, 1032 W. Sheridan Rd., Chicago, IL, 60660, USA.
Hall V; Department of Biology, Loyola University Chicago, Quinlan Life Sciences Education and Research Center, 1032 W. Sheridan Rd., Chicago, IL, 60660, USA.
Hendee J; Department of Biology, Loyola University Chicago, Quinlan Life Sciences Education and Research Center, 1032 W. Sheridan Rd., Chicago, IL, 60660, USA.
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Source:
Scientific reports [Sci Rep] 2024 Mar 02; Vol. 14 (1), pp. 5167. Date of Electronic Publication: 2024 Mar 02.
Publication Type:
Journal Article
MeSH Terms:
Neurons*/physiology
Ion Channels*/physiology
Membrane Potentials/physiology ; Action Potentials ; Magnetic Phenomena ; Electric Stimulation
Academic Journal
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Title:
Intra-ripple frequency accommodation in an inhibitory network model for hippocampal ripple oscillations.
Authors:
Schieferstein N; Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.; Bernstein Center for Computational Neuroscience, Berlin, Germany.
Schwalger T; Bernstein Center for Computational Neuroscience, Berlin, Germany.; Institute for Mathematics, Technische Universität Berlin, Berlin, Germany.
Lindner B; Bernstein Center for Computational Neuroscience, Berlin, Germany.; Department of Physics, Humboldt-Universität zu Berlin, Berlin, Germany.
Kempter R; Institute for Theoretical Biology, Department of Biology, Humboldt-Universität zu Berlin, Berlin, Germany.; Bernstein Center for Computational Neuroscience, Berlin, Germany.; Einstein Center for Neurosciences, Berlin, Germany.
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Source:
PLoS computational biology [PLoS Comput Biol] 2024 Feb 20; Vol. 20 (2), pp. e1011886. Date of Electronic Publication: 2024 Feb 20 (Print Publication: 2024).
Publication Type:
Journal Article
MeSH Terms:
Hippocampus*/physiology
Interneurons*/physiology
Membrane Potentials
Academic Journal
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Title:
Missing Puzzle Pieces in Dementia Research: HCN Channels and Theta Oscillations.
Authors:
Kazmierska-Grebowska P; Department of Neurobiology, Faculty of Biology and Environmental Protection, University of Lodz, Poland.
Jankowski MM; Edmond and Lily Safra Center for Brain Sciences, The Hebrew University of Jerusalem, Jerusalem, Israel.; BioTechMed Center, Multimedia Systems Department, Faculty of Electronics, Telecommunications, and Informatics, Gdansk University of Technology, Gdansk, Poland.Telecommunications and Informatics, Gdansk University of Technology, Gdansk, Poland.
MacIver MB; Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of of Medicine, Stanford University, CA, USA.
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Source:
Aging and disease [Aging Dis] 2024 Feb 01; Vol. 15 (1), pp. 22-42. Date of Electronic Publication: 2024 Feb 01.
Publication Type:
Journal Article; Review
MeSH Terms:
Epilepsy*
Nervous System Physiological Phenomena*
Dementia*
Animals ; Humans ; Membrane Potentials/physiology
Academic Journal
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Title:
Bioelectricity in dental medicine: a narrative review.
Authors:
Min Q; Department of Endodontics, Wuxi Stomatology Hospital, Wuxi, 214000, China.
Gao Y; Department of Endodontics, Wuxi Stomatology Hospital, Wuxi, 214000, China.
Wang Y; Department of Implantology, Wuxi Stomatology Hospital, Wuxi, 214000, China. .
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Source:
Biomedical engineering online [Biomed Eng Online] 2024 Jan 03; Vol. 23 (1), pp. 3. Date of Electronic Publication: 2024 Jan 03.
Publication Type:
Journal Article; Review
MeSH Terms:
Electrophysiological Phenomena*
Mechanotransduction, Cellular*
Cell Membrane ; Ion Channels ; Membrane Potentials
Academic Journal
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Title:
How Merkel cells transduce mechanical stimuli: A biophysical model of Merkel cells.
Authors:
Mao F; Research Center for Humanoid Sensing, Intelligent Perception Research Institute of Zhejiang Lab, Hangzhou, Zhejiang, China.
Yang W; Research Center for Humanoid Sensing, Intelligent Perception Research Institute of Zhejiang Lab, Hangzhou, Zhejiang, China.
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Source:
PLoS computational biology [PLoS Comput Biol] 2023 Dec 20; Vol. 19 (12), pp. e1011720. Date of Electronic Publication: 2023 Dec 20 (Print Publication: 2023).
Publication Type:
Journal Article
MeSH Terms:
Merkel Cells*/physiology
Calcium*/metabolism
Membrane Potentials/physiology ; Neurotransmitter Agents/metabolism
Academic Journal
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Title:
Ca Signaling and ATP Production in Pancreatic Cancer.
Authors:
Gerasimenko JV; Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK.
Gerasimenko OV; Cardiff School of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AX, UK.
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Source:
Function (Oxford, England) [Function (Oxf)] 2023 Dec 08; Vol. 5 (1), pp. zqad067. Date of Electronic Publication: 2023 Dec 08 (Print Publication: 2024).
Publication Type:
Journal Article; Comment
MeSH Terms:
Pancreatic Neoplasms*
Humans ; Membrane Potentials ; Adenosine Triphosphate ; Mutation
Academic Journal
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Title:
Effects of membrane potentials on the electroporation of giant unilamellar vesicles.
Authors:
Wadud MA; Department of Physics, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.
Karal MAS; Department of Physics, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.
Moniruzzaman M; Department of Physics, Bangladesh University of Engineering and Technology, Dhaka, Bangladesh.
Rashid MMO; Department of Pharmacy, Noakhali Science and Technology University, Noakhali, Bangladesh.
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Source:
PloS one [PLoS One] 2023 Sep 12; Vol. 18 (9), pp. e0291496. Date of Electronic Publication: 2023 Sep 12 (Print Publication: 2023).
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Unilamellar Liposomes*
Electroporation*
Membrane Potentials ; Electroporation Therapies ; Biophysics
Academic Journal
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Title:
Impact of weak radiofrequency and static magnetic fields on key signaling molecules, intracellular pH, membrane potential, and cell growth in HT-1080 fibrosarcoma cells.
Authors:
Gurhan H; Department of Electrical, Computer and Energy Engineering, University of Colorado at Boulder, 425 UCB #1B55, Boulder, CO, 80309, USA. .
Barnes F; Department of Electrical, Computer and Energy Engineering, University of Colorado at Boulder, 425 UCB #1B55, Boulder, CO, 80309, USA.
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Source:
Scientific reports [Sci Rep] 2023 Aug 30; Vol. 13 (1), pp. 14223. Date of Electronic Publication: 2023 Aug 30.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Fibrosarcoma*
Drug-Related Side Effects and Adverse Reactions*
Humans ; Membrane Potentials ; Cell Cycle ; Magnetic Fields ; Hydrogen-Ion Concentration
Academic Journal
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Title:
Mitochondrial Dynamics in Neurodegenerative Diseases: Unraveling the Role of Fusion and Fission Processes.
Authors:
Grel H; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Woznica D; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Ratajczak K; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Kalwarczyk E; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Anchimowicz J; Department of Biochemistry and Microbiology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Switlik W; Department of Biochemistry and Microbiology, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Olejnik P; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Zielonka P; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Stobiecka M; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
Jakiela S; Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences, 02-787 Warsaw, Poland.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 22; Vol. 24 (17). Date of Electronic Publication: 2023 Aug 22.
Publication Type:
Journal Article; Review
MeSH Terms:
Mitochondrial Dynamics*/genetics
Neurodegenerative Diseases*/genetics
Humans ; Adenosine Triphosphate ; Membrane Potentials ; Mitochondria/genetics
Academic Journal
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Title:
A Comparative Study on the Lysosomal Cation Channel TMEM175 Using Automated Whole-Cell Patch-Clamp, Lysosomal Patch-Clamp, and Solid Supported Membrane-Based Electrophysiology: Functional Characterization and High-Throughput Screening Assay Development.
Authors:
Bazzone A; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Barthmes M; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
George C; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Brinkwirth N; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Zerlotti R; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.; RIGeL-Regensburg International Graduate School of Life Sciences, University of Regensburg, 93053 Regensburg, Germany.
Prinz V; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Cole K; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Friis S; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
Dickson A; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Rice S; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Lim J; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Fern Toh M; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Mohammadi M; Assay Works, Am BioPark 11, 93053 Regensburg, Germany.
Pau D; SB Drug Discovery, West of Scotland Science Park, Glasgow G20 0XA, UK.
Stone DJ; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Renger JJ; Cerevel Therapeutics, 222 Jacobs St, Cambridge, MA 02141, USA.
Fertig N; Nanion Technologies, Ganghoferstr. 70a, 80339 Munich, Germany.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2023 Aug 14; Vol. 24 (16). Date of Electronic Publication: 2023 Aug 14.
Publication Type:
Journal Article
MeSH Terms:
High-Throughput Screening Assays*
Cardiac Electrophysiology*
Membrane Potentials ; Cations ; Lysosomes
Academic Journal
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Title:
Impaired Functional Connectivity Underlies Fragile X Syndrome.
Authors:
Gildin L; Wolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.; Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Rauti R; Department of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.
Vardi O; Department of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.; School of Electrical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.
Kuznitsov-Yanovsky L; Wolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.; Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.
Maoz BM; Department of Biomedical Engineering, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.; The Center for Nanoscience and Nanotechnology, Tel-Aviv University, Tel-Aviv 69978, Israel.
Segal M; Department of Brain Sciences, The Weizmann Institute, Rehovot 76100, Israel.
Ben-Yosef D; Wolfe PGD Stem Cell Lab, Racine IVF Unit, Lis Maternity Hospital Tel-Aviv Sourasky Medical Center, Tel-Aviv 64239, Israel.; Department of Cell and Developmental Biology, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv 69978, Israel.; Sagol School of Neuroscience, Tel-Aviv University, Tel-Aviv 69978, Israel.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2022 Feb 12; Vol. 23 (4). Date of Electronic Publication: 2022 Feb 12.
Publication Type:
Journal Article
MeSH Terms:
Membrane Potentials*
Transcriptome*
Fragile X Syndrome/*metabolism
Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Cells, Cultured ; Fragile X Mental Retardation Protein/genetics ; Human Embryonic Stem Cells/cytology ; Human Embryonic Stem Cells/metabolism ; Humans ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Neural Stem Cells/physiology ; Neurogenesis ; Rats
Academic Journal
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Title:
Voltage imaging in the olfactory bulb using transgenic mouse lines expressing the genetically encoded voltage indicator ArcLight.
Authors:
Platisa J; The John B. Pierce Laboratory, New Haven, CT, USA. .; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA. .
Zeng H; Allen Institute for Brain Science, Seattle, WA, USA.
Madisen L; Allen Institute for Brain Science, Seattle, WA, USA.
Cohen LB; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA. .; Brain Science Institute, Korea Institute of Science and Technology, Seoul, 136-791, Republic of Korea. .
Pieribone VA; The John B. Pierce Laboratory, New Haven, CT, USA.; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA.; Department of Neuroscience, Yale University, New Haven, CT, USA.
Storace DA; Department of Cellular and Molecular Physiology, Yale University, New Haven, CT, USA. .; Department of Biological Science, Florida State University, Tallahassee, FL, USA. .
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Scientific reports [Sci Rep] 2022 Feb 03; Vol. 12 (1), pp. 1875. Date of Electronic Publication: 2022 Feb 03.
Publication Type:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Biosensing Techniques*
Membrane Potentials*
Voltage-Sensitive Dye Imaging*
Interneurons/*metabolism
Luminescent Proteins/*metabolism
Olfactory Bulb/*metabolism
Olfactory Receptor Neurons/*metabolism
Recombinant Fusion Proteins/*metabolism
Animals ; Genes, Reporter ; Luminescent Proteins/genetics ; Mice, Transgenic ; Microscopy, Fluorescence, Multiphoton ; Odorants ; Olfactory Bulb/cytology ; Olfactory Perception ; Recombinant Fusion Proteins/genetics ; Smell
Academic Journal
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Title:
Electrical polarity-dependent gating and a unique subconductance of RyR2 induced by S-adenosyl methionine via the ATP binding site.
Authors:
Kampfer AJ
Balog EM
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Source:
Journal of biochemistry [J Biochem] 2022 Jan 07; Vol. 170 (6), pp. 739-752.
Publication Type:
Journal Article
MeSH Terms:
Ion Channel Gating*
Membrane Potentials*
Molecular Docking Simulation*
Ryanodine Receptor Calcium Release Channel*/chemistry
Ryanodine Receptor Calcium Release Channel*/metabolism
S-Adenosylmethionine*/chemistry
S-Adenosylmethionine*/metabolism
Animals ; Binding Sites ; Swine
Academic Journal
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Title:
Monitoring of compound resting membrane potentials of cell cultures with ratiometric genetically encoded voltage indicators.
Authors:
Rühl P; Center for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena and Jena University Hospital, D-07745, Jena, Germany.
Langner JM; Center for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena and Jena University Hospital, D-07745, Jena, Germany.
Reidel J; Center for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena and Jena University Hospital, D-07745, Jena, Germany.
Schönherr R; Center for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena and Jena University Hospital, D-07745, Jena, Germany.
Hoshi T; Department of Physiology, University of Pennsylvania, Philadelphia, PA, USA.
Heinemann SH; Center for Molecular Biomedicine, Department of Biophysics, Friedrich Schiller University Jena and Jena University Hospital, D-07745, Jena, Germany. .
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Source:
Communications biology [Commun Biol] 2021 Oct 07; Vol. 4 (1), pp. 1164. Date of Electronic Publication: 2021 Oct 07.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Membrane Potentials*
Ectopic Gene Expression/*physiology
Potassium Channels, Inwardly Rectifying/*genetics
Andersen Syndrome/genetics ; HEK293 Cells ; Hallux/abnormalities ; Humans ; Intellectual Disability/genetics ; Nails, Malformed/genetics ; Potassium Channels, Inwardly Rectifying/metabolism ; Thumb/abnormalities
SCR Disease Name:
Temple-Baraitser Syndrome
Academic Journal
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Title:
Muscimol Directly Activates the TREK-2 Channel Expressed in GABAergic Neurons through Its N-Terminus.
Authors:
Kim EJ; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.
Kwon OS; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.
Hur CG; Cronex Co., Jeju 63078, Korea.
Nyiramana MM; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.; Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea.
Lee DK; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.; Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea.
Hong SG; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.; Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea.
Han J; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.
Kang D; Department of Physiology, College of Medicine and Institute of Health Sciences, Gyeongsang National University, Jinju 52727, Korea.; Department of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea.
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Source:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 27; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 27.
Publication Type:
Journal Article
MeSH Terms:
Membrane Potentials*
GABA-A Receptor Agonists/*pharmacology
GABAergic Neurons/*metabolism
Muscimol/*pharmacology
Potassium Channels, Tandem Pore Domain/*metabolism
Receptors, GABA/*chemistry
Animals ; Cells, Cultured ; GABAergic Neurons/drug effects ; HEK293 Cells ; Humans ; Male ; Mice ; Potassium Channels, Tandem Pore Domain/genetics ; Rats
Academic Journal
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Title:
Cloxyquin activates hTRESK by allosteric modulation of the selectivity filter.
Authors:
Schreiber JA; Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany. .; Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany. .
Derksen A; Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.
Goerges G; Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.
Schütte S; Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
Sörgel J; Westfälische Wilhelms-Universität Münster, Institut für Pharmazeutische und Medizinische Chemie, Corrensstr. 48, Münster, Germany.
Kiper AK; Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
Strutz-Seebohm N; Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.
Ruck T; Department of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Meuth SG; Department of Neurology, Medical Faculty, Heinrich-Heine University, Düsseldorf, Germany.
Decher N; Institute of Physiology and Pathophysiology, Vegetative Physiology, Philipps-University Marburg, Marburg, Germany.
Seebohm G; Institute for Genetics of Heart Diseases (IfGH), Department of Cardiovascular Medicine, University Hospital Münster, Robert-Koch-Str. 45, Münster, Germany.; Westfälische Wilhelms-Universität Münster, GRK 2515, Chemical biology of ion channels (Chembion), Münster, Germany.
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Source:
Communications biology [Commun Biol] 2023 Jul 18; Vol. 6 (1), pp. 745. Date of Electronic Publication: 2023 Jul 18.
Publication Type:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Potassium Channels*/chemistry
Chloroquinolinols*/chemistry
Chloroquinolinols*/pharmacology
Binding Sites ; Membrane Potentials
Academic Journal
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Showing 1-20 from 5356 results

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