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Wyszukujesz frazę ""Membrane Proteins"" wg kryterium: Temat


Tytuł:
Characterization of Adherent-Invasive Escherichia coli (AIEC) Outer Membrane Proteins Provides Potential Molecular Markers to Screen Putative AIEC Strains.
Autorzy:
Saitz W; Programa de Microbiología y Micología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Montero DA; Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.; Centro Integrativo de Biología y Química Aplicada (CIBQA), Universidad Bernardo O'Higgins, Santiago 8370993, Chile.
Pardo M; Programa de Microbiología y Micología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Araya D; Programa de Microbiología y Micología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
De la Fuente M; Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Hermoso MA; Programa de Inmunología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.; Department of Gastroenterology and Hepatology, University Medical Center Groningen (UMCG), University of Groningen, 9712 Groningen, The Netherlands.
Farfán MJ; Departamento de Pediatría y Cirugía Infantil Oriente, Hospital Dr. Luis Calvo Mackenna, Facultad de Medicina, Universidad de Chile, Santiago 7500539, Chile.
Ginard D; Department of Gastroenterology and Palma Health Research Institute, Hospital Universitario Son Espases, 07120 Palma de Mallorca, Spain.
Rosselló-Móra R; Grupo de Microbiología Marina, Instituto Mediterráneo de Estudios Avanzados (IMEDEA; CSIC-UIB), 07190 Esporles, Illes Balears, Spain.
Rasko DA; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201, USA.; Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.
Del Canto F; Programa de Microbiología y Micología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
Vidal RM; Programa de Microbiología y Micología, Instituto de Ciencias Biomédicas, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.; Instituto Milenio de Inmunología e Inmunoterapia, Facultad de Medicina, Universidad de Chile, Santiago 8380453, Chile.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 12; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Outer Membrane Proteins*/genetics
Bacterial Outer Membrane Proteins*/metabolism
Escherichia coli*/metabolism
Escherichia coli Proteins*/genetics
Escherichia coli Proteins*/metabolism
Bacterial Adhesion ; Biomarkers/metabolism ; Escherichia coli Infections ; Intestinal Mucosa/metabolism ; Membrane Proteins/metabolism
Czasopismo naukowe
Tytuł:
A rapid anti-Helicobacter pylori biofilm drug screening biosensor based on AlpB outer membrane protein and colloidal gold/nanoporous gold framework.
Autorzy:
Xiao S; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, PR China.
Shang K; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, PR China.
Zhang L; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, PR China.
Li W; Key Laboratory for Experimental Teratology of Chinese Ministry of Education, The Shandong Provincial Key Laboratory of Infection and Immunology, Department of Microbiology, School of Basic Medical Sciences, Shandong University, Jinan, 250012, PR China.
Wang X; State Key Laboratory of Microbial Technology, Shandong University, Qingdao, 266237, PR China. Electronic address: .
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Źródło:
Biosensors & bioelectronics [Biosens Bioelectron] 2022 Nov 01; Vol. 215, pp. 114599. Date of Electronic Publication: 2022 Jul 31.
Typ publikacji:
Journal Article
MeSH Terms:
Biosensing Techniques*
Curcumin*/pharmacology
Helicobacter Infections*
Helicobacter pylori*
Nanopores*
Bacterial Outer Membrane Proteins/*metabolism
Biofilms ; Drug Evaluation, Preclinical ; Erythromycin ; Gold Colloid ; Humans ; Membrane Proteins ; Molecular Docking Simulation ; Rifampin/pharmacology
Czasopismo naukowe
Tytuł:
IFITM3 regulates fibrinogen endocytosis and platelet reactivity in nonviral sepsis.
Autorzy:
Campbell RA; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.; Department of Internal Medicine.; Department of Pathology, and.
Manne BK; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Banerjee M; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Middleton EA; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.; Department of Internal Medicine.
Ajanel A; Department of Pathology, and.
Schwertz H; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.; Rocky Mountain Center for Occupational and Environmental Health, University of Utah, Salt Lake City, Utah, USA.; Occupational Medicine, Billings Clinic Bozeman, Bozeman, Montana, USA.
Denorme F; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Stubben C; Bioinformatics Shared Resource, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Montenont E; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Saperstein S; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Page L; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Tolley ND; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Lim DL; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.
Brown SM; Division of Pulmonary and Critical Medicine, Department of Medicine, Intermountain Medical Center, Murray, Utah, USA.
Grissom CK; Division of Pulmonary and Critical Medicine, Department of Medicine, Intermountain Medical Center, Murray, Utah, USA.
Sborov DW; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
Krishnan A; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California, USA.; Department of Pathology, Stanford University, Stanford, California, USA.
Rondina MT; University of Utah Molecular Medicine Program, Salt Lake City, Utah, USA.; Department of Internal Medicine.; Department of Pathology, and.; George E. Wahlen Department of Veterans Affairs Medical Center, Department of Internal Medicine, and Geriatric Research, Education, and Clinical Center, Salt Lake City, Utah, USA.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2022 Dec 01; Vol. 132 (23). Date of Electronic Publication: 2022 Dec 01.
Typ publikacji:
Journal Article
MeSH Terms:
Endocytosis*
Fibrinogen*/genetics
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Sepsis*/genetics
Animals ; Mice ; Clathrin
Czasopismo naukowe
Tytuł:
ATP13A1 prevents ERAD of folding-competent mislocalized and misoriented proteins.
Autorzy:
McKenna MJ; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA.
Adams BM; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA.
Chu V; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA.
Paulo JA; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA.
Shao S; Department of Cell Biology, Harvard Medical School, 240 Longwood Ave., Boston, MA 02115, USA. Electronic address: sichen_.
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Źródło:
Molecular cell [Mol Cell] 2022 Nov 17; Vol. 82 (22), pp. 4277-4289.e10. Date of Electronic Publication: 2022 Oct 24.
Typ publikacji:
Journal Article
MeSH Terms:
Endoplasmic Reticulum-Associated Degradation*
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Animals ; Endoplasmic Reticulum/metabolism ; Adenosine Triphosphatases/genetics ; Adenosine Triphosphatases/metabolism ; Mitochondrial Proteins/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Protein Sorting Signals ; Protein Folding ; Mammals/metabolism
Czasopismo naukowe
Tytuł:
H3.3-G34 mutations impair DNA repair and promote cGAS/STING-mediated immune responses in pediatric high-grade glioma models.
Autorzy:
Haase S; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Banerjee K; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Mujeeb AA; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Hartlage CS; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Núñez FM; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Núñez FJ; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Alghamri MS; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Kadiyala P; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Carney S; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Barissi MN; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Taher AW; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Brumley EK; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Thompson S; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Dreyer JT; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Alindogan CT; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Garcia-Fabiani MB; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Comba A; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Venneti S; Department of Pathology.
Ravikumar V; Departments of Bioinformatics and Computational Biology, and.
Koschmann C; Division of Pediatric Hematology/Oncology, Department of Pediatrics, C.S. Mott Children's Hospital, University of Michigan, Ann Arbor, Michigan, USA.
Carcaboso ÁM; Institut de Recerca Sant Joan de Deu, Barcelona, Spain.
Vinci M; Department of Onco-Haematology, Gene and Cell Therapy, Bambino Gesù Children's Hospital-IRCCS, Rome, Italy.
Rao A; Departments of Bioinformatics and Computational Biology, and.; Radiation Oncology, University of Michigan, Ann Arbor, Michigan, USA.
Yu JS; Department of Cancer Biology, Lerner Research Institute and.; Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Lowenstein PR; Department of Neurosurgery.; Department of Cell and Developmental Biology.
Castro MG; Department of Neurosurgery.; Department of Cell and Developmental Biology.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2022 Nov 15; Vol. 132 (22). Date of Electronic Publication: 2022 Nov 15.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Brain Neoplasms*/genetics
DNA Repair*/drug effects
DNA Repair*/genetics
Glioma*/genetics
Histones*/genetics
Nucleotidyltransferases*/genetics
Nucleotidyltransferases*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Cytokines*/immunology
Animals ; Child ; Humans ; Mice ; Young Adult ; Immunity ; Mutation ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use
Czasopismo naukowe
Tytuł:
Structure of the GOLD-domain seven-transmembrane helix protein family member TMEM87A.
Autorzy:
Hoel CM; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, United States.; California Institute for Quantitative Biology (QB3), University of California, Berkeley, Berkeley, United States.
Zhang L; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, United States.; California Institute for Quantitative Biology (QB3), University of California, Berkeley, Berkeley, United States.
Brohawn SG; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, United States.; Helen Wills Neuroscience Institute, University of California, Berkeley, Berkeley, United States.; California Institute for Quantitative Biology (QB3), University of California, Berkeley, Berkeley, United States.
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Źródło:
ELife [Elife] 2022 Nov 14; Vol. 11. Date of Electronic Publication: 2022 Nov 14.
Typ publikacji:
Journal Article
MeSH Terms:
Golgi Apparatus*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Humans ; Protein Transport ; Receptors, G-Protein-Coupled/metabolism ; Family
Czasopismo naukowe
Tytuł:
miR-125a-3p aggravates ox-LDL-induced HUVEC injury through BAMBI.
Autorzy:
Xia F; Department of Cardiovascular Surgery, Wuhan Asia General Hospital, Wuhan, Hubei, China.
Zeng Q; Department of Cardiovascular Surgery, Wuhan Asia General Hospital, Wuhan, Hubei, China.
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Źródło:
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2022 Nov; Vol. 36 (11), pp. e23198. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/genetics
Atherosclerosis*/metabolism
Human Umbilical Vein Endothelial Cells*/metabolism
Human Umbilical Vein Endothelial Cells*/pathology
Lipoproteins, LDL*/genetics
Lipoproteins, LDL*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Humans ; Apoptosis/genetics ; Apoptosis/physiology ; Cell Proliferation/genetics ; Cell Proliferation/physiology
Czasopismo naukowe
Tytuł:
Nr1d1 Mediated Cell Senescence in Mouse Heart-Derived Sca-1 Cells.
Autorzy:
Pu S; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; Research Center for Biomedical Sciences, Guangxi Normal University, Guilin 541004, China.; Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Guangxi Normal University, Ministry of Education, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.
Wang Q; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.
Liu Q; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.
Zhao H; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; Research Center for Biomedical Sciences, Guangxi Normal University, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.; Faculty of Biological and Environmental Sciences, University of Helsinki, 00790 Helsinki, Finland.
Zhou Z; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; Research Center for Biomedical Sciences, Guangxi Normal University, Guilin 541004, China.; Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Guangxi Normal University, Ministry of Education, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.
Wu Q; Guangxi Universities Key Laboratory of Stem Cell and Biopharmaceutical Technology, Guangxi Normal University, Guilin 541004, China.; Research Center for Biomedical Sciences, Guangxi Normal University, Guilin 541004, China.; Key Laboratory of Ecology of Rare and Endangered Species and Environmental Protection, Guangxi Normal University, Ministry of Education, Guilin 541004, China.; School of Life Sciences, Guangxi Normal University, Guilin 541004, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Oct 18; Vol. 23 (20). Date of Electronic Publication: 2022 Oct 18.
Typ publikacji:
Journal Article
MeSH Terms:
Antigens, Ly*/genetics
Antigens, Ly*/metabolism
Membrane Proteins*/genetics
Membrane Proteins*/metabolism
Mice ; Animals ; Cellular Senescence/genetics ; Myocytes, Cardiac/metabolism ; Cells, Cultured ; RNA, Messenger/metabolism ; beta-Galactosidase/metabolism ; Mice, Inbred C57BL ; Mammals/metabolism ; Nuclear Receptor Subfamily 1, Group D, Member 1/metabolism
Czasopismo naukowe
Tytuł:
In Situ Analysis of Membrane-Protein Binding Kinetics and Cell-Surface Adhesion Using Plasmonic Scattering Microscopy.
Autorzy:
Zhang P; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.
Zhou X; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.
Jiang J; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.
Kolay J; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.
Wang R; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.
Ma G; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.
Wan Z; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.; School of Electrical, Energy and Computer Engineering, Arizona State University, Tempe, AZ 85287, USA.
Wang S; Biodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, AZ 85287, USA.; School of Biological and Health Systems Engineering, Arizona State University, Tempe, AZ 85287, USA.
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Źródło:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2022 Oct 17; Vol. 61 (42), pp. e202209469. Date of Electronic Publication: 2022 Aug 23.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Membrane Proteins*
Microscopy*
Kinetics ; Ligands ; Protein Binding ; Surface Plasmon Resonance
Czasopismo naukowe
Tytuł:
Foldable Detergents for Membrane Protein Stability.
Autorzy:
Youn T; Department of Bionano Engineering, Center of Bionano Intelligence Research and Education, Hanyang University, Ansan, 155-88, South Korea.
Yoon S; Department of Bionano Engineering, Center of Bionano Intelligence Research and Education, Hanyang University, Ansan, 155-88, South Korea.
Byrne B; Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK.
Chae PS; Department of Bionano Engineering, Center of Bionano Intelligence Research and Education, Hanyang University, Ansan, 155-88, South Korea.
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Źródło:
Chembiochem : a European journal of chemical biology [Chembiochem] 2022 Oct 06; Vol. 23 (19), pp. e202200276. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Detergents*/chemistry
Membrane Proteins*/chemistry
Micelles ; Protein Stability ; Triazines
Czasopismo naukowe
Tytuł:
Active role of glia-like supporting cells in the organ of Corti: Membrane proteins and their roles in hearing.
Autorzy:
Jang MW; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Republic of Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Lim J; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, Republic of Korea.
Park MG; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Republic of Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Lee JH; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Lee CJ; KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul, Republic of Korea.; Center for Cognition and Sociality, Institute for Basic Science (IBS), Daejeon, Republic of Korea.; IBS School, University of Science and Technology (UST), Daejeon, Republic of Korea.
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Źródło:
Glia [Glia] 2022 Oct; Vol. 70 (10), pp. 1799-1825. Date of Electronic Publication: 2022 Jun 17.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Membrane Proteins*
Organ of Corti*/physiology
Cochlea/physiology ; Hearing/physiology ; Neuroglia
Czasopismo naukowe
Tytuł:
MITA/STING-mediated antiviral immunity and autoimmunity: the evolution, mechanism, and intervention.
Autorzy:
Zhong B; Department of Gastrointestinal Surgery, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China; Research Unit of Innate Immune and Inflammatory Diseases, Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan 430071, China. Electronic address: .
Shu HB; Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan 430071, China; Research Unit of Innate Immune and Inflammatory Diseases, Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan 430071, China. Electronic address: .
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Źródło:
Current opinion in immunology [Curr Opin Immunol] 2022 Oct; Vol. 78, pp. 102248. Date of Electronic Publication: 2022 Sep 30.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Autoimmune Diseases*/immunology
Autoimmune Diseases*/metabolism
Interferon Type I*
Membrane Proteins*/immunology
Membrane Proteins*/metabolism
Animals ; Humans ; Mice ; Autoimmunity ; Immunity, Innate ; Virus Diseases/immunology ; Virus Diseases/metabolism
Czasopismo naukowe
Tytuł:
Tailoring Butyl Methacrylate/Methacrylic Acid Copolymers for the Solubilization of Membrane Proteins: The Influence of Composition and Molecular Weight.
Autorzy:
Janata M; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 06, Czech Republic.
Čadová E; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 06, Czech Republic.
Angelisová P; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 20, Czech Republic.
Charnavets T; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 20, Czech Republic.; Institute of Biotechnology of the Czech Academy of Sciences, BIOCEV, Průmyslová 595, Vestec, CZ-25242, Czech Republic.
Hořejší V; Institute of Molecular Genetics of the Czech Academy of Sciences, Vídeňská 1083, Prague 4, 142 20, Czech Republic.
Raus V; Institute of Macromolecular Chemistry, Czech Academy of Sciences, Heyrovského nám. 2, Prague 6, 162 06, Czech Republic.
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Źródło:
Macromolecular bioscience [Macromol Biosci] 2022 Oct; Vol. 22 (10), pp. e2200284. Date of Electronic Publication: 2022 Aug 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Membrane Proteins*/chemistry
Polystyrenes*/chemistry
Methacrylates ; Molecular Weight ; Polymers/chemistry ; Sodium Dodecyl Sulfate
Czasopismo naukowe
Tytuł:
Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Autorzy:
Marei H; Discovery Oncology, Genentech, South San Francisco, CA, USA.
Tsai WK; Antibody Engineering, Genentech, South San Francisco, CA, USA.
Kee YS; Antibody Engineering, Genentech, South San Francisco, CA, USA.
Ruiz K; Discovery Oncology, Genentech, South San Francisco, CA, USA.
He J; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Cox C; Discovery Immunology, Genentech Inc, South San Francisco, CA, USA.
Sun T; Molecular Biology, Genentech, South San Francisco, CA, USA.
Penikalapati S; Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA, USA.
Dwivedi P; Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA, USA.
Choi M; Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA, USA.
Kan D; Translational Oncology, Genentech, South San Francisco, CA, USA.
Saenz-Lopez P; Translational Oncology, Genentech, South San Francisco, CA, USA.
Dorighi K; Molecular Biology, Genentech, South San Francisco, CA, USA.
Zhang P; Antibody Engineering, Genentech, South San Francisco, CA, USA.
Kschonsak YT; Discovery Oncology, Genentech, South San Francisco, CA, USA.
Kljavin N; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Amin D; Discovery Oncology, Genentech, South San Francisco, CA, USA.
Kim I; Antibody Engineering, Genentech, South San Francisco, CA, USA.
Mancini AG; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Nguyen T; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Wang C; Discovery Oncology, Genentech, South San Francisco, CA, USA.
Janezic E; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Doan A; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Mai E; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Xi H; Antibody discovery, Genentech, South San Francisco, CA, USA.
Gu C; Protein Chemistry, Genentech, South San Francisco, CA, USA.
Heinlein M; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Biehs B; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Wu J; Antibody discovery, Genentech, South San Francisco, CA, USA.
Lehoux I; Biomolecular Resources, Genentech, South San Francisco, CA, USA.
Harris S; Structural Biology, Genentech, South San Francisco, CA, USA.
Comps-Agrar L; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Seshasayee D; Antibody discovery, Genentech, South San Francisco, CA, USA.
de Sauvage FJ; Molecular Oncology, Genentech, South San Francisco, CA, USA.
Grimmer M; Discovery Oncology, Genentech, South San Francisco, CA, USA.
Li J; Biochemical and Cellular Pharmacology, Genentech, South San Francisco, CA, USA.
Agard NJ; Antibody Engineering, Genentech, South San Francisco, CA, USA. .
de Sousa E Melo F; Discovery Oncology, Genentech, South San Francisco, CA, USA. .
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Źródło:
Nature [Nature] 2022 Oct; Vol. 610 (7930), pp. 182-189. Date of Electronic Publication: 2022 Sep 21.
Typ publikacji:
Journal Article
MeSH Terms:
Antibodies*/immunology
Antibodies*/metabolism
Antibody Specificity*
Membrane Proteins*/immunology
Membrane Proteins*/metabolism
Proteolysis*
Ubiquitin-Protein Ligases*/immunology
Ubiquitin-Protein Ligases*/metabolism
Animals ; Colorectal Neoplasms/metabolism ; Ligands ; Receptors, Cell Surface/immunology ; Receptors, Cell Surface/metabolism ; Substrate Specificity
Czasopismo naukowe
Tytuł:
Centrosome de-clustering of cancer cells induces cGAS-STING-mediated innate immunity of tumor-associated tumor cells in response to irradiation.
Autorzy:
Kim S; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, 139-706, South Korea. Electronic address: .
Choe MH; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, 139-706, South Korea. Electronic address: .
Oh JS; Department of Integrative Biotechnology, College of Biotechnology and Bioengineering, Sungkyunkwan University, Suwon, South Korea. Electronic address: .
Kim JS; Division of Radiation Biomedical Research, Korea Institute of Radiological and Medical Sciences, Seoul, 139-706, South Korea. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 25; Vol. 636 (Pt 2), pp. 24-30. Date of Electronic Publication: 2022 Oct 31.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/radiotherapy
Centrosome*/metabolism
Immunity, Innate*
Membrane Proteins*/metabolism
Animals ; Female ; Humans ; Mice ; Nucleotidyltransferases/metabolism
Czasopismo naukowe
Tytuł:
VSTM5 is a novel immune checkpoint that promotes oral tolerance of cell-mediated and antibody responses.
Autorzy:
Oludada OE; Department of Microbiology and Immunology, Innovative Therapeutics Research Institute, Inje University College of Medicine, Busan, South Korea.
Idowu TO; Department of Microbiology and Immunology, Innovative Therapeutics Research Institute, Inje University College of Medicine, Busan, South Korea.
Jeon Y; Department of Microbiology and Immunology, Innovative Therapeutics Research Institute, Inje University College of Medicine, Busan, South Korea.
Choi I; Department of Microbiology and Immunology, Innovative Therapeutics Research Institute, Inje University College of Medicine, Busan, South Korea. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Dec 20; Vol. 635, pp. 283-290. Date of Electronic Publication: 2022 Oct 20.
Typ publikacji:
Journal Article
MeSH Terms:
Antibody Formation*
Immune Tolerance*
Membrane Proteins*/metabolism
Animals ; Mice ; Immunoglobulins ; Ovalbumin ; Phylogeny ; T-Lymphocytes, Regulatory
Czasopismo naukowe
Tytuł:
Medicinal chemistry perspective on cGAS-STING signaling pathway with small molecule inhibitors.
Autorzy:
Tian X; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Xu F; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Zhu Q; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Feng Z; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Dai W; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Zhou Y; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
You QD; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China.
Xu X; State Key Laboratory of Natural Medicines, and Jiang Su Key Laboratory of Drug Design and Optimization, China Pharmaceutical University, Nanjing, 210009, China; Department of Medicinal Chemistry, School of Pharmacy, China Pharmaceutical University, Nanjing, 210009, China. Electronic address: xuxiao_.
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Źródło:
European journal of medicinal chemistry [Eur J Med Chem] 2022 Dec 15; Vol. 244, pp. 114791. Date of Electronic Publication: 2022 Sep 24.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Chemistry, Pharmaceutical*
Membrane Proteins*
Nucleotidyltransferases/metabolism ; Signal Transduction ; Immunity, Innate
Czasopismo naukowe
Tytuł:
Single-molecule approaches reveal outer membrane protein biogenesis dynamics.
Autorzy:
Svirina A; TU Dresden, B CUBE - Center for Molecular Bioengineering, Dresden, Germany.
Chamachi N; TU Dresden, B CUBE - Center for Molecular Bioengineering, Dresden, Germany.
Schlierf M; TU Dresden, B CUBE - Center for Molecular Bioengineering, Dresden, Germany.; Cluster of Excellence Physics of Life, Technische Universität Dresden, Dresden, Germany.
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Źródło:
BioEssays : news and reviews in molecular, cellular and developmental biology [Bioessays] 2022 Dec; Vol. 44 (12), pp. e2200149. Date of Electronic Publication: 2022 Oct 25.
Typ publikacji:
Journal Article
MeSH Terms:
Bacterial Outer Membrane Proteins*/metabolism
Gram-Negative Bacteria*
Molecular Chaperones/metabolism ; Porins/metabolism ; Protein Folding
Czasopismo naukowe
Tytuł:
Mitochondrial fission factor (MFF) frameshift variant in Bullmastiffs with mitochondrial fission encephalopathy.
Autorzy:
Christen M; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Gutierrez-Quintana R; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Vandenberghe H; Highcroft Veterinary Referrals, Bristol, UK.
Kaczmarska A; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Penderis J; Vet-Extra Neurology, Stirling, UK.
José-López R; Hamilton Specialist Referrals, IVC Evidensia, High Wycombe, UK.
Rupp A; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Griffiths IR; School of Veterinary Medicine, College of Medical Veterinary and Life Sciences, University of Glasgow, Glasgow, UK.
Jagannathan V; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Leeb T; Institute of Genetics, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
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Źródło:
Animal genetics [Anim Genet] 2022 Dec; Vol. 53 (6), pp. 814-820. Date of Electronic Publication: 2022 Sep 09.
Typ publikacji:
Journal Article
MeSH Terms:
Dogs*/genetics
Brain Diseases*/genetics
Brain Diseases*/veterinary
Dog Diseases*/genetics
Dog Diseases*/pathology
Membrane Proteins*/genetics
Mitochondrial Proteins*/genetics
Animals ; Frameshift Mutation ; Homozygote ; Mitochondria/genetics ; Mitochondrial Dynamics ; Transcription Factors/genetics
SCR Disease Name:
Mitochondrial encephalopathy
Czasopismo naukowe
Tytuł:
SPRY1 promotes cell proliferation and inhibits apoptosis by activating Hedgehog pathway in acute myeloid leukemia.
Autorzy:
Lv G; Department of Hematology, Affiliated Qingdao Central Hospital, Qingdao University, Shandong, People's Republic of China.
Wang Y; Department of Hematology, Affiliated Qingdao Central Hospital, Qingdao University, Shandong, People's Republic of China.
Ji C; Department of Hematology, Affiliated Qingdao Central Hospital, Qingdao University, Shandong, People's Republic of China.
Shi C; Department of Hematology, Affiliated Qingdao Central Hospital, Qingdao University, Shandong, People's Republic of China.
Li Y; Department of Hematology, Affiliated Qingdao Central Hospital, Qingdao University, Shandong, People's Republic of China.
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Źródło:
Hematology (Amsterdam, Netherlands) [Hematology] 2022 Dec; Vol. 27 (1), pp. 1-10.
Typ publikacji:
Journal Article
MeSH Terms:
Signal Transduction*
Apoptosis/*genetics
Hedgehog Proteins/*metabolism
Leukemia, Myeloid, Acute/*etiology
Leukemia, Myeloid, Acute/*metabolism
Membrane Proteins/*genetics
Phosphoproteins/*genetics
Biomarkers, Tumor ; Cell Cycle/genetics ; Cell Line, Tumor ; Cell Proliferation ; Computational Biology/methods ; Disease Susceptibility ; Gene Expression Profiling ; Gene Expression Regulation, Leukemic ; HL-60 Cells ; Humans ; K562 Cells ; Kaplan-Meier Estimate ; Leukemia, Myeloid, Acute/mortality ; Leukemia, Myeloid, Acute/pathology ; Membrane Proteins/metabolism ; Phosphoproteins/metabolism ; Prognosis
Czasopismo naukowe

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