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Wyszukujesz frazę ""Membrane Proteins"" wg kryterium: Temat


Tytuł :
Application of TonB-Dependent Transporters in Vaccine Development of Gram-Negative Bacteria.
Autorzy :
Wang J; Department of Clinical Laboratory, Traditional Medicine Hospital Affiliated to Southwest Medical University, Luzhou, China.
Xiong K; Department of Cold Environmental Medicine, Institute of High Altitude Military Medicine, Army Medical University, Chongqiong, China.
Pan Q; Department of Microbiology, Chengdu Medical College, Chengdu, China.
He W; Department of Burn, Southwest Hospital, Army Medical University, Chongqing, China.
Cong Y; Department of Clinical Laboratory, Traditional Medicine Hospital Affiliated to Southwest Medical University, Luzhou, China.; Precision Medicine Center, Traditional Medicine Hospital Affiliated to Southwest Medical University, Luzhou, China.
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Źródło :
Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2021 Jan 27; Vol. 10, pp. 589115. Date of Electronic Publication: 2021 Jan 27 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Membrane Proteins*/metabolism
Vaccines*
Bacterial Outer Membrane Proteins/metabolism ; Bacterial Proteins/genetics ; Bacterial Proteins/metabolism ; Gram-Negative Bacteria/metabolism ; Membrane Transport Proteins/genetics
Czasopismo naukowe
Tytuł :
Proton Detected Solid-State NMR of Membrane Proteins at 28 Tesla (1.2 GHz) and 100 kHz Magic-Angle Spinning.
Autorzy :
Nimerovsky E; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Movellan KT; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Zhang XC; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Forster MC; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Najbauer E; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Xue K; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Dervişoǧlu R; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Giller K; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Griesinger C; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Becker S; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
Andreas LB; Department for NMR-Based Structural Biology, Max-Planck-Institute for Biophysical Chemistry, 37077 Göttingen, Germany.
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Źródło :
Biomolecules [Biomolecules] 2021 May 18; Vol. 11 (5). Date of Electronic Publication: 2021 May 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Geobacillus/*metabolism
Influenza A virus/*metabolism
Membrane Proteins/*chemistry
Neisseria gonorrhoeae/*metabolism
Proton Magnetic Resonance Spectroscopy/*instrumentation
Bacterial Outer Membrane Proteins/chemistry ; Humans ; Magnetic Fields ; Models, Molecular ; Protein Kinases/chemistry ; Protein Structure, Secondary ; Viral Matrix Proteins/chemistry ; Voltage-Dependent Anion Channels/chemistry
SCR Organism :
Geobacillus thermodenitrificans
Czasopismo naukowe
Tytuł :
Tetraspanin TM4SF5 in hepatocytes negatively modulates SLC27A transporters during acute fatty acid supply.
Autorzy :
Park D; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Kim E; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee H; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Shin EA; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee H; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee JW; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 15; Vol. 710, pp. 109004. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fatty Acid Transport Proteins/*metabolism
Fatty Acids/*metabolism
Hepatocytes/*metabolism
Membrane Proteins/*metabolism
Animals ; Biological Transport, Active ; Cell Line ; Energy Metabolism ; Fatty Acid Transport Proteins/antagonists & inhibitors ; Fatty Acid Transport Proteins/genetics ; HEK293 Cells ; Hep G2 Cells ; Humans ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/deficiency ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Models, Biological ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; Oxygen Consumption ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
The cGAS-STING pathway as a therapeutic target in inflammatory diseases.
Autorzy :
Decout A; Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland.
Katz JD; IFM Therapeutics, Boston, MA, USA.
Venkatraman S; IFM Therapeutics, Boston, MA, USA.
Ablasser A; Global Health Institute, Swiss Federal Institute of Technology Lausanne (EPFL), Lausanne, Switzerland. .
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Źródło :
Nature reviews. Immunology [Nat Rev Immunol] 2021 Sep; Vol. 21 (9), pp. 548-569. Date of Electronic Publication: 2021 Apr 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Adaptor Proteins, Signal Transducing/*antagonists & inhibitors
Inflammation/*therapy
Membrane Proteins/*antagonists & inhibitors
Nucleotidyltransferases/*antagonists & inhibitors
Adaptor Proteins, Signal Transducing/genetics ; Adaptor Proteins, Signal Transducing/immunology ; Animals ; Autophagy ; Cell Death ; Cell Proliferation ; DNA, Mitochondrial/genetics ; DNA, Mitochondrial/metabolism ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/therapeutic use ; Gain of Function Mutation ; Humans ; Inflammation/immunology ; Inflammation/metabolism ; Inflammation Mediators/antagonists & inhibitors ; Inflammation Mediators/immunology ; Inflammation Mediators/metabolism ; Membrane Proteins/genetics ; Membrane Proteins/immunology ; Models, Biological ; Models, Molecular ; Nucleotides, Cyclic/immunology ; Nucleotides, Cyclic/metabolism ; Nucleotidyltransferases/genetics ; Nucleotidyltransferases/immunology ; Signal Transduction/drug effects ; Signal Transduction/genetics ; Signal Transduction/immunology
Czasopismo naukowe
Tytuł :
Targeting pyruvate kinase muscle isoform 2 (PKM2) in cancer: What do we know so far?
Autorzy :
Chhipa AS; Department of Pharmacology, Nirma University, Ahmedabad, Gujarat, India.
Patel S; Department of Pharmacology, Nirma University, Ahmedabad, Gujarat, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Sep 01; Vol. 280, pp. 119694. Date of Electronic Publication: 2021 Jun 06.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Carrier Proteins/*metabolism
Membrane Proteins/*metabolism
Neoplasms/*metabolism
Thyroid Hormones/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Carcinogenesis/drug effects ; Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Carrier Proteins/agonists ; Carrier Proteins/analysis ; Carrier Proteins/antagonists & inhibitors ; Drug Discovery ; Enzyme Activation/drug effects ; Enzyme Activators/pharmacology ; Enzyme Inhibitors/pharmacology ; Humans ; Membrane Proteins/agonists ; Membrane Proteins/analysis ; Membrane Proteins/antagonists & inhibitors ; Molecular Targeted Therapy ; Neoplasms/drug therapy ; Neoplasms/pathology ; Thyroid Hormones/agonists ; Thyroid Hormones/analysis
Czasopismo naukowe
Tytuł :
PGRS Domain of Rv0297 of Mycobacterium tuberculosis Functions in A Calcium Dependent Manner.
Autorzy :
Sharma T; Kusuma School of Biological Sciences, Indian Institute of Technology, Hauz Khas, New Delhi 110016, India.; ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Singh J; JH-Institute of Molecular Medicine, Jamia Hamdard, Tughlaqabad, New Delhi 110062, India.
Grover S; JH-Institute of Molecular Medicine, Jamia Hamdard, Tughlaqabad, New Delhi 110062, India.
P M; ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.; JH-Institute of Molecular Medicine, Jamia Hamdard, Tughlaqabad, New Delhi 110062, India.
Firdos F; Kusuma School of Biological Sciences, Indian Institute of Technology, Hauz Khas, New Delhi 110016, India.
Alam A; ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Ehtesham NZ; ICMR-National Institute of Pathology, Safdarjung Hospital Campus, New Delhi 110029, India.
Hasnain SE; Department of Biochemical Engineering and Biotechnology, Indian Institute of Technology, Hauz Khas, New Delhi 110016, India.; Dr. Reddy's Institute of Life Sciences, University of Hyderabad Campus, Prof C.R. Rao Road, Hyderabad 500019, India.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 30; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 30.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Antigens, Bacterial/*metabolism
Bacterial Proteins/*metabolism
Calcium/*metabolism
Macrophages/*metabolism
Membrane Proteins/*metabolism
Mycobacterium tuberculosis/*metabolism
Amino Acid Sequence ; Animals ; Antigens, Bacterial/chemistry ; Antigens, Bacterial/genetics ; Bacterial Proteins/chemistry ; Bacterial Proteins/genetics ; Humans ; Macrophages/microbiology ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Mice ; Molecular Dynamics Simulation ; Mycobacterium tuberculosis/growth & development ; Protein Conformation ; Sequence Homology
Czasopismo naukowe
Tytuł :
Structures of a deAMPylation complex rationalise the switch between antagonistic catalytic activities of FICD.
Autorzy :
Perera LA; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. .
Preissler S; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Zaccai NR; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK.
Prévost S; Institut Laue-Langevin, Grenoble, France.
Devos JM; Institut Laue-Langevin, Grenoble, France.
Haertlein M; Institut Laue-Langevin, Grenoble, France.
Ron D; Cambridge Institute for Medical Research, University of Cambridge, Cambridge, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 18; Vol. 12 (1), pp. 5004. Date of Electronic Publication: 2021 Aug 18.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Adenosine Monophosphate/*metabolism
Heat-Shock Proteins/*chemistry
Heat-Shock Proteins/*metabolism
Membrane Proteins/*chemistry
Membrane Proteins/*metabolism
Nucleotidyltransferases/*chemistry
Nucleotidyltransferases/*metabolism
Adenosine Monophosphate/chemistry ; Adenosine Triphosphate/chemistry ; Adenosine Triphosphate/metabolism ; Amino Acid Motifs ; Biocatalysis ; Dimerization ; Heat-Shock Proteins/genetics ; Humans ; Membrane Proteins/genetics ; Nucleotidyltransferases/genetics ; Protein Processing, Post-Translational
Czasopismo naukowe
Tytuł :
Listeria exploits IFITM3 to suppress antibacterial activity in phagocytes.
Autorzy :
Tan JMJ; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
Garner ME; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.
Regeimbal JM; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Greene CJ; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
Márquez JDR; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Ammendolia DA; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
McCluggage ARR; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Li T; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Wu KJ; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Cemma M; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada.
Ostrowski PP; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.
Diamond MS; Departments of Medicine, Molecular Microbiology, Pathology & Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Grinstein S; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.; Institute of Medical Science, University of Toronto, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada.
Yates RM; Department of Biochemistry and Molecular Biology, University of Calgary, Calgary, AB, Canada.
Higgins DE; Department of Microbiology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. .
Brumell JH; Cell Biology Program, Hospital for Sick Children, Toronto, ON, Canada. .; Institute of Medical Science, University of Toronto, Toronto, ON, Canada. .; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada. .; SickKids IBD Centre, Hospital for Sick Children, Toronto, ON, Canada. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 17; Vol. 12 (1), pp. 4999. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Anti-Bacterial Agents/*pharmacology
Listeria/*drug effects
Listeriosis/*immunology
Membrane Proteins/*antagonists & inhibitors
Membrane Proteins/*metabolism
Phagocytes/*immunology
Phagocytes/*microbiology
Animals ; Disease Models, Animal ; Host-Pathogen Interactions ; Interferon Type I/metabolism ; Listeria monocytogenes/immunology ; Male ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phagosomes/immunology ; RAW 264.7 Cells ; Transcriptome ; Virulence Factors ; Virus Internalization/drug effects
Czasopismo naukowe
Tytuł :
Cryo-EM structures of the TTYH family reveal a novel architecture for lipid interactions.
Autorzy :
Sukalskaia A; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Straub MS; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Deneka D; Department of Biochemistry, University of Zurich, Zurich, Switzerland.
Sawicka M; Department of Biochemistry, University of Zurich, Zurich, Switzerland. .
Dutzler R; Department of Biochemistry, University of Zurich, Zurich, Switzerland. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 12; Vol. 12 (1), pp. 4893. Date of Electronic Publication: 2021 Aug 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chloride Channels/*ultrastructure
Cryoelectron Microscopy/*methods
Membrane Proteins/*ultrastructure
Neoplasm Proteins/*ultrastructure
Chloride Channels/chemistry ; Chloride Channels/metabolism ; Humans ; Ion Channels/chemistry ; Ion Channels/metabolism ; Ion Channels/ultrastructure ; Lipid Bilayers/metabolism ; Membrane Proteins/chemistry ; Membrane Proteins/metabolism ; Models, Molecular ; Neoplasm Proteins/chemistry ; Neoplasm Proteins/metabolism ; Protein Binding ; Protein Conformation
Czasopismo naukowe
Tytuł :
Building Better Barrels - β-barrel Biogenesis and Insertion in Bacteria and Mitochondria.
Autorzy :
Diederichs KA; Laboratory of Molecular Biology, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Buchanan SK; Laboratory of Molecular Biology, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA.
Botos I; Laboratory of Molecular Biology, National Institute of Diabetes & Digestive & Kidney Diseases, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA. Electronic address: .
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Źródło :
Journal of molecular biology [J Mol Biol] 2021 Aug 06; Vol. 433 (16), pp. 166894. Date of Electronic Publication: 2021 Feb 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Intramural; Review
MeSH Terms :
Bacterial Outer Membrane Proteins/*genetics
Bacterial Outer Membrane Proteins/*metabolism
Gram-Negative Bacteria/*physiology
Mitochondria/*genetics
Mitochondria/*metabolism
Bacterial Outer Membrane Proteins/chemistry ; Chloroplasts/genetics ; Chloroplasts/metabolism ; Models, Molecular ; Multiprotein Complexes/chemistry ; Multiprotein Complexes/metabolism ; Protein Binding ; Structure-Activity Relationship
Czasopismo naukowe
Tytuł :
Development of a Bispecific Antibody-Based Platform for Retargeting of Capsid Modified AAV Vectors.
Autorzy :
Kuklik J; Division of Cancer Immunology and Immune Modulation, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.
Michelfelder S; Division of Research Beyond Borders, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.
Schiele F; Division of Biotherapeutics Discovery, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.
Kreuz S; Division of Research Beyond Borders, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.; Boehringer Ingelheim Venture Fund GmbH, 55216 Ingelheim am Rhein, Germany.
Lamla T; Division of Drug Discovery Sciences Biberach, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.
Müller P; Boehringer Ingelheim Venture Fund GmbH, 55216 Ingelheim am Rhein, Germany.
Park JE; Division of Cancer Immunology and Immune Modulation, Boehringer Ingelheim Pharma GmbH & Co. KG, 88387 Biberach an der Riss, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 03; Vol. 22 (15). Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article
MeSH Terms :
Antibodies, Bispecific/*immunology
Capsid/*immunology
Capsid Proteins/*immunology
Dependovirus/*genetics
Endopeptidases/*immunology
Epitopes/*immunology
Genetic Vectors/*administration & dosage
Membrane Proteins/*immunology
Capsid/metabolism ; Capsid Proteins/genetics ; Capsid Proteins/metabolism ; Endopeptidases/genetics ; Endopeptidases/metabolism ; Gene Transfer Techniques ; Genetic Therapy ; Genetic Vectors/genetics ; Humans ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Proprotein Convertase 9/genetics ; Proprotein Convertase 9/immunology ; Proprotein Convertase 9/metabolism ; Transduction, Genetic
Czasopismo naukowe
Tytuł :
Mechanism of LolCDE as a molecular extruder of bacterial triacylated lipoproteins.
Autorzy :
Sharma S; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA.
Zhou R; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Wan L; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Feng S; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China.
Song K; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.; Cryo-EM Core Facility, University of Massachusetts Medical School, Worcester, MA, USA.
Xu C; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA, USA.; Cryo-EM Core Facility, University of Massachusetts Medical School, Worcester, MA, USA.
Li Y; Key Laboratory of Structural Biology of Zhejiang Province, School of Life Sciences, Westlake University, Hangzhou, China. .
Liao M; Department of Cell Biology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA. .
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Źródło :
Nature communications [Nat Commun] 2021 Aug 03; Vol. 12 (1), pp. 4687. Date of Electronic Publication: 2021 Aug 03.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
ATP-Binding Cassette Transporters/*metabolism
Bacterial Outer Membrane Proteins/*metabolism
Lipoproteins/*metabolism
ATP-Binding Cassette Transporters/chemistry ; ATP-Binding Cassette Transporters/genetics ; Acylation ; Adenosine Triphosphate/metabolism ; Bacterial Outer Membrane Proteins/chemistry ; Bacterial Outer Membrane Proteins/genetics ; Binding Sites ; Cell Membrane/metabolism ; Cryoelectron Microscopy ; Escherichia coli/genetics ; Escherichia coli/metabolism ; Hydrophobic and Hydrophilic Interactions ; Mutation ; Periplasm/metabolism ; Protein Conformation ; Protein Transport
Czasopismo naukowe
Tytuł :
Molecular characterization, expression and functional analysis of yak IFITM3 gene.
Autorzy :
Wang H; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China.
Wang L; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China. Electronic address: .
Li J; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China.
Fu F; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China.
Zheng Y; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China.
Zhang L; Key Laboratory of Qinghai-Tibetan Plateau Animal Genetic Resource Reservation and Utilization, Ministry of Education and Sichuan Province, Southwest Minzu University, Chengdu 610041, China.
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Źródło :
International journal of biological macromolecules [Int J Biol Macromol] 2021 Aug 01; Vol. 184, pp. 349-357. Date of Electronic Publication: 2021 Jun 11.
Typ publikacji :
Journal Article
MeSH Terms :
Cloning, Molecular/*methods
Membrane Proteins/*genetics
Membrane Proteins/*metabolism
3' Untranslated Regions ; 5' Untranslated Regions ; Animals ; Cattle ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Humans ; Kidney/chemistry ; Liver/chemistry ; Lung/chemistry ; MCF-7 Cells ; Membrane Proteins/pharmacology ; Molecular Weight ; Myocardium/chemistry ; Spleen/chemistry ; Tissue Distribution
Czasopismo naukowe
Tytuł :
The PDZ protein SCRIB regulates sodium/iodide symporter (NIS) expression at the basolateral plasma membrane.
Autorzy :
Martín M; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Salleron L; Transporteurs, Imagerie et Radiothérapie en Oncologie, Faculté de médecine, Direction de la Recherche Fondamentale, Commissariat à l'Energie Atomique et aux énergies alternatives, Université Côte d'Azur, Institut des sciences du vivant Fréderic Joliot, Nice, France.
Peyret V; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Geysels RC; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Darrouzet E; Transporteurs, Imagerie et Radiothérapie en Oncologie, Faculté de médecine, Direction de la Recherche Fondamentale, Commissariat à l'Energie Atomique et aux énergies alternatives, Université Côte d'Azur, Institut des sciences du vivant Fréderic Joliot, Nice, France.
Lindenthal S; Transporteurs, Imagerie et Radiothérapie en Oncologie, Faculté de médecine, Direction de la Recherche Fondamentale, Commissariat à l'Energie Atomique et aux énergies alternatives, Université Côte d'Azur, Institut des sciences du vivant Fréderic Joliot, Nice, France.
Bernal Barquero CE; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Masini-Repiso AM; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
Pourcher T; Transporteurs, Imagerie et Radiothérapie en Oncologie, Faculté de médecine, Direction de la Recherche Fondamentale, Commissariat à l'Energie Atomique et aux énergies alternatives, Université Côte d'Azur, Institut des sciences du vivant Fréderic Joliot, Nice, France.
Nicola JP; Departamento de Bioquímica Clínica, Facultad de Ciencias Químicas, Universidad Nacional de Córdoba, Córdoba, Argentina.; Centro de Investigaciones en Bioquímica Clínica e Inmunología (CIBICI), Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Córdoba, Argentina.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Aug; Vol. 35 (8), pp. e21681.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Membrane Proteins/*metabolism
Symporters/*metabolism
Tumor Suppressor Proteins/*metabolism
Amino Acid Sequence ; Animals ; Cell Line ; Cell Membrane/metabolism ; Codon, Nonsense ; Congenital Hypothyroidism/genetics ; Congenital Hypothyroidism/metabolism ; Conserved Sequence ; Dogs ; Endosomes/metabolism ; HEK293 Cells ; Humans ; Lysosomes/metabolism ; Madin Darby Canine Kidney Cells ; Membrane Proteins/chemistry ; Membrane Proteins/genetics ; Models, Molecular ; Mutagenesis, Site-Directed ; PDZ Domains/genetics ; Protein Structure, Secondary ; Rats ; Recombinant Fusion Proteins/chemistry ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/metabolism ; Symporters/chemistry ; Symporters/genetics ; Thyroid Gland/metabolism ; Tumor Suppressor Proteins/chemistry ; Tumor Suppressor Proteins/genetics
Czasopismo naukowe
Tytuł :
8-Formylophiopogonanone B antagonizes doxorubicin-induced cardiotoxicity by suppressing heme oxygenase-1-dependent myocardial inflammation and fibrosis.
Autorzy :
Qin D; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Yue R; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Deng P; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Wang X; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Zheng Z; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Lv M; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Zhang Y; Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Pu J; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China.
Xu J; Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China.
Liang Y; School of Medicine, Guangxi University, Nanning, Guangxi Zhuang Autonomous Region 530004, China.
Pi H; Academician Workstation, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Yu Z; Department of Occupational Health, Third Military Medical University, Chongqing 400038, China.
Hu H; Department of Cardiology, Affiliated Hospital of North Sichuan Medical College, No. 63, Wenhua Road, Shunqing District, Nanchong, Sichuan 637000, China; Academician Workstation, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan 637000, China. Electronic address: .
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Źródło :
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2021 Aug; Vol. 140, pp. 111779. Date of Electronic Publication: 2021 May 29.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents*
Doxorubicin*
Cardiotonic Agents/*therapeutic use
Cardiotoxicity/*drug therapy
Heme Oxygenase-1/*antagonists & inhibitors
Isoflavones/*therapeutic use
Membrane Proteins/*antagonists & inhibitors
Animals ; Cardiotonic Agents/pharmacology ; Cardiotoxicity/genetics ; Cardiotoxicity/metabolism ; Cardiotoxicity/pathology ; Cytokines/genetics ; Fibrosis ; Heme Oxygenase-1/genetics ; Heme Oxygenase-1/metabolism ; Inflammation/drug therapy ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Isoflavones/pharmacology ; Male ; Membrane Proteins/genetics ; Membrane Proteins/metabolism ; Mice, Inbred C57BL ; Myocardium/metabolism ; Myocardium/pathology
Czasopismo naukowe
Tytuł :
Visible on-site detection of Ara h 1 by the switchable-linker-mediated precipitation of gold nanoparticles.
Autorzy :
Kim E; Department of Agricultural Biotechnology, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea.
Hahn J; Center for Food and Bioconvergence, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea.
Ban C; Department of Environmental Horticulture, University of Seoul, 163 Seoulsiripdaero, Dongdaemun-gu, Seoul 02504, Republic of Korea.
Jo Y; Crop Post-harvest Technology Division, Department of Central Area Crop Science, National Institute of Crop Science, Rural Development Administration, Suwon 16429, Republic of Korea.
Han H; Department of Agricultural Biotechnology, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea.
Lim S; Department of Food Science and Biotechnology, College of BioNano Technology, Gachon University, Seongnam-Si, Gyeonggi-Do 13120, Republic of Korea. Electronic address: .
Choi YJ; Department of Agricultural Biotechnology, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea; Center for Food and Bioconvergence, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea; Research Institute for Agriculture and Life Sciences, Seoul National University, 1 Gwanakro, Gwanakgu, Seoul 08826, Republic of Korea. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2021 Aug 01; Vol. 352, pp. 129354. Date of Electronic Publication: 2021 Feb 20.
Typ publikacji :
Journal Article
MeSH Terms :
Chemical Precipitation*
Antigens, Plant/*analysis
Antigens, Plant/*isolation & purification
Gold/*chemistry
Membrane Proteins/*analysis
Membrane Proteins/*isolation & purification
Metal Nanoparticles/*chemistry
Plant Proteins/*analysis
Plant Proteins/*isolation & purification
Antigens, Plant/immunology ; Humans ; Membrane Proteins/immunology ; Peanut Hypersensitivity ; Plant Proteins/immunology
Czasopismo naukowe
Tytuł :
Membrane protein production and formulation for drug discovery.
Autorzy :
Gulezian E; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Crivello C; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Bednenko J; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Zafra C; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Zhang Y; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Colussi P; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA.
Hussain S; TetraGenetics Inc., 91 Mystic Street, Arlington, MA 02474, USA. Electronic address: .
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Źródło :
Trends in pharmacological sciences [Trends Pharmacol Sci] 2021 Aug; Vol. 42 (8), pp. 657-674.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Drug Discovery*
Membrane Proteins*
Antibodies, Monoclonal ; Drug Design ; Humans ; Ion Channels
Czasopismo naukowe
Tytuł :
GRAMD1-mediated accessible cholesterol sensing and transport.
Autorzy :
Naito T; Lee Kong Chian School of Medicine, Nanyang Technological University, 308232, Singapore.
Saheki Y; Lee Kong Chian School of Medicine, Nanyang Technological University, 308232, Singapore; Institute of Resource Development and Analysis, Kumamoto University, Kumamoto 860-0811, Japan. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Molecular and cell biology of lipids [Biochim Biophys Acta Mol Cell Biol Lipids] 2021 Aug; Vol. 1866 (8), pp. 158957. Date of Electronic Publication: 2021 Apr 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Cholesterol/*metabolism
Membrane Proteins/*metabolism
Animals ; Biological Transport ; Evolution, Molecular ; Humans ; Membrane Proteins/chemistry ; Membrane Proteins/genetics
Czasopismo naukowe
Tytuł :
Carbocation Footprinting of Soluble and Transmembrane Proteins.
Autorzy :
Sun J; Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States.
Li S; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Li W; Department of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, Missouri 63110, United States.
Gross ML; Department of Chemistry, Washington University in St. Louis, St. Louis, Missouri 63130, United States.
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Źródło :
Analytical chemistry [Anal Chem] 2021 Oct 05; Vol. 93 (39), pp. 13101-13105. Date of Electronic Publication: 2021 Sep 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Membrane Proteins*
Czasopismo naukowe
Tytuł :
Adamantane derivatives as potential inhibitors of p37 major envelope protein and poxvirus reproduction. Design, synthesis and antiviral activity.
Autorzy :
Shiryaev VA; Department of Organic Chemistry, Samara State Technical University, 244 Molodogvardeyskaya St., Samara, Samara Region, 443100, Russia. Electronic address: .
Skomorohov MY; Department of Organic Chemistry, Samara State Technical University, 244 Molodogvardeyskaya St., Samara, Samara Region, 443100, Russia.
Leonova MV; Department of Organic Chemistry, Samara State Technical University, 244 Molodogvardeyskaya St., Samara, Samara Region, 443100, Russia.
Bormotov NI; State Research Centre of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, 630559, Russia.
Serova OA; State Research Centre of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, 630559, Russia.
Shishkina LN; State Research Centre of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, 630559, Russia.
Agafonov AP; State Research Centre of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, 630559, Russia.
Maksyutov RA; State Research Centre of Virology and Biotechnology VECTOR, Koltsovo, Novosibirsk Region, 630559, Russia.
Klimochkin YN; Department of Organic Chemistry, Samara State Technical University, 244 Molodogvardeyskaya St., Samara, Samara Region, 443100, Russia.
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Źródło :
European journal of medicinal chemistry [Eur J Med Chem] 2021 Oct 05; Vol. 221, pp. 113485. Date of Electronic Publication: 2021 Apr 29.
Typ publikacji :
Journal Article
MeSH Terms :
Drug Design*
Adamantane/*pharmacology
Antiviral Agents/*pharmacology
Membrane Proteins/*antagonists & inhibitors
Poxviridae/*drug effects
Viral Envelope Proteins/*antagonists & inhibitors
Adamantane/chemical synthesis ; Adamantane/chemistry ; Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Dose-Response Relationship, Drug ; Membrane Proteins/metabolism ; Microbial Sensitivity Tests ; Molecular Structure ; Structure-Activity Relationship ; Viral Envelope Proteins/metabolism
Czasopismo naukowe

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