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Wyszukujesz frazę ""Mendelian Randomization Analysis"" wg kryterium: Temat


Tytuł :
A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer.
Autorzy :
Gormley M; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK. .; Bristol Dental Hospital and School, University of Bristol, Bristol, BS1 2LY, UK. .; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK. .
Dudding T; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Bristol Dental Hospital and School, University of Bristol, Bristol, BS1 2LY, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.
Sanderson E; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.
Martin RM; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; University Hospitals Bristol and Weston NHS Foundation Trust National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, Bristol, BS1 3NU, UK.
Thomas S; Bristol Dental Hospital and School, University of Bristol, Bristol, BS1 2LY, UK.; University Hospitals Bristol and Weston NHS Foundation Trust National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, Bristol, BS1 3NU, UK.
Tyrrell J; RD&E Hospital, University of Exeter Medical School, RILD Building, Exeter, UK.
Ness AR; University Hospitals Bristol and Weston NHS Foundation Trust National Institute for Health Research Bristol Biomedical Research Centre, University of Bristol, Bristol, BS1 3NU, UK.
Brennan P; Genetic Epidemiology Group, World Health Organization, International Agency for Research on Cancer, Lyon, France.
Munafò M; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; School of Psychological Science, Faculty of Life Sciences, University of Bristol, Bristol, BS8 1TL, UK.
Pring M; Bristol Dental Hospital and School, University of Bristol, Bristol, BS1 2LY, UK.
Boccia S; Section of Hygiene, University Department of Life Sciences and Public Health, Università Cattolica del Sacro Cuore, Roma, Italia.; Department of Woman and Child Health and Public Health-Public Health Area, Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Olshan AF; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, 27599, USA.
Diergaarde B; Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, and UPMC Hillman Cancer Center, Pittsburgh, PA, 15260, USA.
Hung RJ; Prosserman Centre for Population Health Research, Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Canada.; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.
Liu G; Dalla Lana School of Public Health, University of Toronto, Toronto, Canada.; Princess Margaret Cancer Centre, Toronto, Canada.
Davey Smith G; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.
Richmond RC; MRC Integrative Epidemiology Unit, Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.; Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, BS8 1TL, UK.
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Źródło :
Nature communications [Nat Commun] 2020 Nov 27; Vol. 11 (1), pp. 6071. Date of Electronic Publication: 2020 Nov 27.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mendelian Randomization Analysis*
Alcohol Drinking/*genetics
Mouth Neoplasms/*genetics
Oropharyngeal Neoplasms/*genetics
Smoking/*genetics
Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Multivariate Analysis ; Polymorphism, Single Nucleotide/genetics ; Risk Factors ; Sexual Partners
Czasopismo naukowe
Tytuł :
Morning diurnal preference and food intake: a Mendelian randomization study.
Autorzy :
Dashti HS; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.
Chen A; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Daghlas I; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.
Saxena R; Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Broad Institute, Cambridge, MA, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Division of Sleep Medicine, Harvard Medical School, Boston, MA, USA.
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Źródło :
The American journal of clinical nutrition [Am J Clin Nutr] 2020 Nov 11; Vol. 112 (5), pp. 1348-1357.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mendelian Randomization Analysis*
Circadian Rhythm/*physiology
Eating/*genetics
Adult ; Diet/statistics & numerical data ; Diet Records ; Feeding Behavior ; Female ; Genome-Wide Association Study ; Humans ; Male
Czasopismo naukowe
Tytuł :
Genetically raised serum bilirubin levels and lung cancer: a cohort study and Mendelian randomisation using UK Biobank.
Autorzy :
Horsfall LJ; Department of Primary Care & Population Health, UCL, London, UK .
Burgess S; MRC Biostatistics Unit, University of Cambridge Institute of Public Health, Cambridge, Cambridgeshire, UK.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, Cambridge University, Cambridge, Cambridgeshire, UK.
Hall I; Division of Respiratory Medicine, University of Nottingham, Nottingham, Nottinghamshire, UK.
Nazareth I; Department of Primary Care & Population Health, UCL, London, UK.
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Źródło :
Thorax [Thorax] 2020 Nov; Vol. 75 (11), pp. 955-964. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mendelian Randomization Analysis*
Bilirubin/*blood
Bilirubin/*genetics
Lung Neoplasms/*epidemiology
Adult ; Aged ; Biological Specimen Banks ; Causality ; Female ; Humans ; Incidence ; Male ; Middle Aged ; Registries ; Smoking/epidemiology ; United Kingdom/epidemiology
Czasopismo naukowe
Tytuł :
A unified framework for joint-tissue transcriptome-wide association and Mendelian randomization analysis.
Autorzy :
Zhou D; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. .; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. .
Jiang Y; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Center of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Zhong X; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Cox NJ; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA.; Data Science Institute, Vanderbilt University Medical Center, Nashville, TN, USA.
Liu C; Center of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; Department of Psychiatry, SUNY Upstate Medical University, Syracuse, NY, USA.
Gamazon ER; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA. .; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA. .; Data Science Institute, Vanderbilt University Medical Center, Nashville, TN, USA. .; Clare Hall, University of Cambridge, Cambridge, UK. .; MRC Epidemiology Unit, University of Cambridge, Cambridge, UK. .
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Źródło :
Nature genetics [Nat Genet] 2020 Nov; Vol. 52 (11), pp. 1239-1246. Date of Electronic Publication: 2020 Oct 05.
Typ publikacji :
Comparative Study; Evaluation Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Profiling*
Mendelian Randomization Analysis*
Models, Genetic*
Genetic Association Studies/*methods
Animals ; Humans ; Lipoproteins, LDL/genetics ; Mice ; Multifactorial Inheritance/genetics ; Predictive Value of Tests
Czasopismo naukowe
Tytuł :
Protective effect of club cell secretory protein (CC-16) on COPD risk and progression: a Mendelian randomisation study.
Autorzy :
Milne S; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada .; Division of Respiratory Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.; Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.
Li X; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
Hernandez Cordero AI; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
Yang CX; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
Cho MH; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Beaty TH; Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Ruczinski I; Department of Biostatistics, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, USA.
Hansel NN; Pulmonary and Critical Care Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.
Bossé Y; Institut universitaire de cardiologie et de pneumologie de Québec, Department of Molecular Medicine, Laval University, Québec City, Québec, Canada.
Brandsma CA; University of Groningen Department of Pathology and Medical Biology, University Medical Centre Groningen, Groningen, The Netherlands.
Sin DD; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.; Division of Respiratory Medicine, The University of British Columbia, Vancouver, British Columbia, Canada.
Obeidat M; Centre for Heart Lung Innovation, St Paul's Hospital, The University of British Columbia, Vancouver, British Columbia, Canada.
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Źródło :
Thorax [Thorax] 2020 Nov; Vol. 75 (11), pp. 934-943. Date of Electronic Publication: 2020 Aug 24.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mendelian Randomization Analysis*
Pulmonary Disease, Chronic Obstructive/*genetics
Uteroglobin/*blood
Adult ; Disease Progression ; Female ; Genome-Wide Association Study ; Humans ; Longitudinal Studies ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Pulmonary Disease, Chronic Obstructive/blood ; Respiratory Function Tests ; Risk
Czasopismo naukowe
Tytuł :
Toward Preventive Psychiatry: The Role of Advanced Epidemiological Methods.
Autorzy :
Firth J; Division of Psychology and Mental Health, University of Manchester, Manchester, U.K. (Firth); NICM Health Research Institute, Western Sydney University, Westmead, Australia (Firth); MRC Integrative Epidemiology Unit, University of Bristol, and Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, U.K. (Wootton); Department of Psychiatry, University of Toronto, and Centre for Addiction and Mental Health, Toronto (Carvalho).
Wootton RE; Division of Psychology and Mental Health, University of Manchester, Manchester, U.K. (Firth); NICM Health Research Institute, Western Sydney University, Westmead, Australia (Firth); MRC Integrative Epidemiology Unit, University of Bristol, and Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, U.K. (Wootton); Department of Psychiatry, University of Toronto, and Centre for Addiction and Mental Health, Toronto (Carvalho).
Carvalho AF; Division of Psychology and Mental Health, University of Manchester, Manchester, U.K. (Firth); NICM Health Research Institute, Western Sydney University, Westmead, Australia (Firth); MRC Integrative Epidemiology Unit, University of Bristol, and Department of Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, U.K. (Wootton); Department of Psychiatry, University of Toronto, and Centre for Addiction and Mental Health, Toronto (Carvalho).
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Źródło :
The American journal of psychiatry [Am J Psychiatry] 2020 Oct 01; Vol. 177 (10), pp. 888-890.
Typ publikacji :
Editorial; Research Support, Non-U.S. Gov't; Comment
MeSH Terms :
Mendelian Randomization Analysis*
Preventive Psychiatry*
Depression ; Epidemiologic Methods ; Genome-Wide Association Study ; Humans ; Risk Factors
Raport
Tytuł :
Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases.
Autorzy :
Zheng J; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK. .; Proteome MR writing group, . .
Haberland V; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.
Baird D; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.
Walker V; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.
Haycock PC; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.
Hurle MR; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Gutteridge A; Human Genetics, GlaxoSmithKline, Stevenage, UK.
Erola P; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Liu Y; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Luo S; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, Hong Kong, China.
Robinson J; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Richardson TG; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Staley JR; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Elsworth B; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Burgess S; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Sun BB; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.
Danesh J; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; BHF Centre of Research Excellence, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Hinxton, UK.; Department of Human Genetics, Wellcome Sanger Institute, Hinxton, UK.
Runz H; Translational Biology, Biogen, Cambridge, MA, USA.
Maranville JC; Informatics and Predictive Sciences, Celgene Corporation, Cambridge, MA, USA.
Martin HM; School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
Yarmolinsky J; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Laurin C; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.
Holmes MV; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Medical Research Council Population Health Research Unit, University of Oxford, Oxford, UK.; Clinical Trial Service Unit & Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, UK.; National Institute for Health Research, Oxford Biomedical Research Centre, Oxford University Hospital, Oxford, UK.
Liu JZ; Translational Biology, Biogen, Cambridge, MA, USA.
Estrada K; Translational Biology, Biogen, Cambridge, MA, USA.
Santos R; Functional Genomics, GlaxoSmithKline, Stevenage, Hertfordshire, UK.
McCarthy L; Human Genetics, GlaxoSmithKline, Stevenage, UK.
Waterworth D; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Nelson MR; Human Genetics, GlaxoSmithKline, Collegeville, PA, USA.
Smith GD; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.; NIHR Bristol Biomedical Research Centre, Bristol, UK.
Butterworth AS; Proteome MR writing group.; BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; BHF Centre of Research Excellence, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Hinxton, UK.
Hemani G; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK.; Proteome MR writing group.
Scott RA; Proteome MR writing group, . .; Human Genetics, GlaxoSmithKline, Stevenage, UK. .
Gaunt TR; MRC Integrative Epidemiology Unit (IEU), Bristol Medical School, University of Bristol, Bristol, UK. .; Proteome MR writing group, . .; NIHR Bristol Biomedical Research Centre, Bristol, UK. .
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Źródło :
Nature genetics [Nat Genet] 2020 Oct; Vol. 52 (10), pp. 1122-1131. Date of Electronic Publication: 2020 Sep 07.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Genetic Predisposition to Disease*
Mendelian Randomization Analysis*
Blood Proteins/*genetics
Proteome/*genetics
Genome-Wide Association Study ; Humans ; Phenotype ; Polymorphism, Single Nucleotide/genetics
Czasopismo naukowe
Tytuł :
Physical activity and risk of Alzheimer disease: A 2-sample mendelian randomization study.
Autorzy :
Baumeister SE; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany. .
Karch A; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany.
Bahls M; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany.
Teumer A; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany.
Leitzmann MF; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany.
Baurecht H; From Epidemiology (S.E.B.), LMU München, UNIKA-T Augsburg; Independent Research Group, Clinical Epidemiology (S.E.B.), Helmholtz Zentrum München, German Research Center for Environmental Health, Munich; Institute of Epidemiology and Social Medicine (A.K.), University of Münster; Department of Internal Medicine B (M.B.) and Institute for Community Medicine (A.T.), University Medicine Greifswald; DZHK (German Centre for Cardiovascular Research) (M.B., A.T.), Partner Site Greifswald; and Department of Epidemiology and Preventive Medicine (M.F.L., H.B.), University of Regensburg, Germany.
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Źródło :
Neurology [Neurology] 2020 Sep 29; Vol. 95 (13), pp. e1897-e1905. Date of Electronic Publication: 2020 Jul 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Exercise*
Mendelian Randomization Analysis*
Alzheimer Disease/*genetics
Genetic Predisposition to Disease/*genetics
Aged ; Aged, 80 and over ; Biological Specimen Banks ; Case-Control Studies ; Female ; Genome-Wide Association Study/statistics & numerical data ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Risk Factors
Czasopismo naukowe
Tytuł :
Polycystic ovary syndrome and lung function: a Mendelian randomization study.
Autorzy :
van der Plaat DA; Unité Mixte de Recherche 1152, Department of Pathophysiology and Epidemiology of Respiratory Diseases, Institut National de la Santé et de la Recherche Médicale; Unité Mixte de Recherche 1152, University Paris Diderot, Paris, France; National Heart and Lung Institute, Imperial College London, Emmanuel Kaye Building, 1B Manresa Road, London SW3 6LR, United Kingdom. Electronic address: .
Minelli C; National Heart and Lung Institute, Imperial College London, Emmanuel Kaye Building, 1B Manresa Road, London SW3 6LR, United Kingdom.
Jarvis DL; National Heart and Lung Institute, Imperial College London, Emmanuel Kaye Building, 1B Manresa Road, London SW3 6LR, United Kingdom.
Garcia-Aymerich J; ISGlobal; Universitat Pompeu Fabra; Centro de Investigación Biomédica en Red Epidemiología y Salud Pública, Barcelona, Spain.
Leynaert B; Unité 1168, VIMA (Aging and Chronic Diseases. Epidemiological and Public Health Approaches), Institut National de la Santé et de la Recherche Médicale, Villejuif, France; Unité Mixte de Recherche en Santé 1168, UVSQ, Université Versailles St-Quentin-en-Yvelines, St-Quentin-en-Yvelines, France.
Gómez-Real F; Department of Clinical Science, University of Bergen; Department of Gynecology and Obstetrics, Haukeland University Hospital, Bergen, Norway.
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Źródło :
American journal of obstetrics and gynecology [Am J Obstet Gynecol] 2020 Sep; Vol. 223 (3), pp. 455-457. Date of Electronic Publication: 2020 Mar 07.
Typ publikacji :
Letter; Research Support, Non-U.S. Gov't
MeSH Terms :
Mendelian Randomization Analysis*
Lung/*physiopathology
Polycystic Ovary Syndrome/*genetics
Polycystic Ovary Syndrome/*physiopathology
Adult ; Aged ; Female ; Humans ; Middle Aged ; Polymorphism, Single Nucleotide ; Respiratory Function Tests
Raport
Tytuł :
Modifiable lifestyle factors and heart failure: A Mendelian randomization study.
Autorzy :
van Oort S; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute and Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands. Electronic address: .
Beulens JWJ; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute and Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.
van Ballegooijen AJ; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute and Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands; Department of Nephrology, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.
Handoko ML; Department of Cardiology, Amsterdam Cardiovascular Sciences Research Institute, Amsterdam University Medical Center, location VUmc, Amsterdam, the Netherlands.
Larsson SC; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
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Źródło :
American heart journal [Am Heart J] 2020 Sep; Vol. 227, pp. 64-73. Date of Electronic Publication: 2020 Jun 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Life Style*
Mendelian Randomization Analysis*
Heart Failure/*genetics
Heart Failure/*prevention & control
Female ; Heart Failure/epidemiology ; Humans ; Male ; Risk Factors
Czasopismo naukowe
Tytuł :
[Challenges and factors that influencing causal inference and interpretation, based on Mendelian randomization studies].
Autorzy :
Wang YZ; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
Shen HB; Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
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Źródło :
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi [Zhonghua Liu Xing Bing Xue Za Zhi] 2020 Aug 10; Vol. 41 (8), pp. 1231-1236.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Causality*
Mendelian Randomization Analysis*
Genetic Variation ; Humans
Czasopismo naukowe
Tytuł :
[Evaluating the causal relationship between hip circumference and coronary heart disease: a Mendelian randomization study].
Autorzy :
Yuan T; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Li H; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Ma Y; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Si S; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Liu X; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Yu Y; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Li Y; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Li W; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Hou L; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Liu L; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Zhou Y; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Xue F; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Wang P; Operating Room of Qilu Hospital, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
Liu Y; Institute for Medical Dataology, Chelloo College of Medicine, Shandong University, Department of Biostatistics, School of Public Health, Chelloo College of Medicine, Shandong University, Jinan 250012, China.
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Źródło :
Wei sheng yan jiu = Journal of hygiene research [Wei Sheng Yan Jiu] 2020 May; Vol. 49 (3), pp. 362-367.
Typ publikacji :
Journal Article
MeSH Terms :
Coronary Disease*
Mendelian Randomization Analysis*
Genetic Predisposition to Disease ; Genome-Wide Association Study ; Humans ; Polymorphism, Single Nucleotide
Czasopismo naukowe
Tytuł :
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis.
Autorzy :
Gao Y; Department of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China.
Wang T; Department of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China.
Yu X; Department of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China.
Zhao H; Department of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China. .; Center for Medical Statistics and Data Analysis, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China. .
Zeng P; Department of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China. .; Center for Medical Statistics and Data Analysis, School of Public Health, Xuzhou Medical University, Xuzhou, 221004, Jiangsu, People's Republic of China. .
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Corporate Authors :
International FTD-Genomics Consortium (IFGC)
Źródło :
Scientific reports [Sci Rep] 2020 Jul 22; Vol. 10 (1), pp. 12184. Date of Electronic Publication: 2020 Jul 22.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Frontotemporal Dementia*/genetics
Frontotemporal Dementia*/pathology
Mendelian Randomization Analysis*
Amyotrophic Lateral Sclerosis/*pathology
Leukocytes/*metabolism
Telomere/*physiology
Amyotrophic Lateral Sclerosis/genetics ; Asian Continental Ancestry Group/genetics ; Cholesterol/blood ; European Continental Ancestry Group/genetics ; Genome-Wide Association Study ; Humans ; Leukocytes/cytology ; Lipoproteins, LDL/blood ; Odds Ratio ; Polymorphism, Single Nucleotide ; Proportional Hazards Models ; Telomerase/genetics ; Telomere Shortening
Czasopismo naukowe
Tytuł :
Linking protein to phenotype with Mendelian Randomization detects 38 proteins with causal roles in human diseases and traits.
Autorzy :
Bretherick AD; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Canela-Xandri O; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Joshi PK; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Clark DW; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Rawlik K; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Boutin TS; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Zeng Y; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.; Guangdong Province Translational Forensic Medicine Engineering Technology Research Center, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China.
Amador C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Navarro P; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Rudan I; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Campbell H; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; Centre for Global Health Research, Usher Institute, University of Edinburgh, Teviot Place, Edinburgh, Scotland, United Kingdom.
Tenesa A; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Ponting CP; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.
Baillie JK; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
Haley C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, Scotland, United Kingdom.; The Roslin Institute, University of Edinburgh, Easter Bush, Edinburgh, Scotland, United Kingdom.
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Źródło :
PLoS genetics [PLoS Genet] 2020 Jul 06; Vol. 16 (7), pp. e1008785. Date of Electronic Publication: 2020 Jul 06 (Print Publication: 2020).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mendelian Randomization Analysis*
Cardiovascular Diseases/*genetics
Proteome/*genetics
Schizophrenia/*genetics
Antigens, Differentiation/genetics ; Cardiovascular Diseases/pathology ; Fatty Acid-Binding Proteins/genetics ; Female ; Fibroblast Growth Factor 5/genetics ; Genetic Association Studies/methods ; Humans ; Lipoprotein Lipase/genetics ; Lymphotoxin-alpha/genetics ; Male ; Quantitative Trait Loci ; Receptors, Immunologic/genetics ; Receptors, Interleukin-6/genetics ; Schizophrenia/pathology
Czasopismo naukowe
Tytuł :
Education leads to a more physically active lifestyle: Evidence based on Mendelian randomization.
Autorzy :
Kari JT; Jyväskylä University School of Business and Economics, University of Jyväskylä, Jyväskylä, Finland.
Viinikainen J; Jyväskylä University School of Business and Economics, University of Jyväskylä, Jyväskylä, Finland.
Böckerman P; Jyväskylä University School of Business and Economics, University of Jyväskylä, Jyväskylä, Finland.; Labour Institute for Economic Research, Helsinki, Finland.; IZA Institute of Labor Economics, Bonn, Germany.
Tammelin TH; LIKES Research Centre for Physical Activity and Health, Jyväskylä, Finland.
Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, Turku University Hospital, University of Turku, Turku, Finland.
Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and Faculty of Medicine and Health Technology, Finnish Cardiovascular Research Center - Tampere, Tampere University, Tampere, Finland.
Pahkala K; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, Turku University Hospital, University of Turku, Turku, Finland.; Paavo Nurmi Centre, Sports & Exercise Medicine Unit, Department of Physical Activity and Health, Turku, Finland.
Hirvensalo M; Faculty of Sport and Health Sciences, University of Jyväskylä, Jyväskylä, Finland.
Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland.; Centre for Population Health Research, Turku University Hospital, University of Turku, Turku, Finland.; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.
Pehkonen J; Jyväskylä University School of Business and Economics, University of Jyväskylä, Jyväskylä, Finland.
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Źródło :
Scandinavian journal of medicine & science in sports [Scand J Med Sci Sports] 2020 Jul; Vol. 30 (7), pp. 1194-1204. Date of Electronic Publication: 2020 Mar 29.
Typ publikacji :
Journal Article
MeSH Terms :
Education*
Exercise*
Life Style*
Mendelian Randomization Analysis*
Adult ; Cross-Sectional Studies ; Female ; Finland ; Humans ; Longitudinal Studies ; Male ; Middle Aged
Czasopismo naukowe
Tytuł :
Reply to: Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues.
Autorzy :
Mukamal KJ; Departments of Nutrition and Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Rimm EB; Departments of Nutrition and Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA.
Stampfer MJ; Departments of Nutrition and Epidemiology, Harvard TH Chan School of Public Health, Boston, MA, USA. .
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Źródło :
European journal of epidemiology [Eur J Epidemiol] 2020 Jul; Vol. 35 (7), pp. 725-726. Date of Electronic Publication: 2020 Jun 11.
Typ publikacji :
Letter; Comment
MeSH Terms :
Mendelian Randomization Analysis*
Models, Genetic*
Humans
Opinia redakcyjna
Tytuł :
Mendelian randomization in COVID-19: Applications for cardiovascular comorbidities and beyond.
Autorzy :
Teng Y; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Basic Medical Sciences, Tsinghua University School of Medicine, Beijing, China.
Xu J; Department of Basic Medical Sciences, Tsinghua University School of Medicine, Beijing, China.
Zhang Y; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Liu Z; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Zhang S; Department of Cardiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China; Department of Basic Medical Sciences, Tsinghua University School of Medicine, Beijing, China. Electronic address: .
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Źródło :
EBioMedicine [EBioMedicine] 2020 Jul; Vol. 57, pp. 102847. Date of Electronic Publication: 2020 Jun 20.
Typ publikacji :
Journal Article
MeSH Terms :
Mendelian Randomization Analysis*
Cardiovascular Diseases/*complications
Coronary Artery Disease/*complications
Coronavirus Infections/*epidemiology
Diabetes Mellitus/*pathology
Genetic Predisposition to Disease/*genetics
Pneumonia, Viral/*epidemiology
Betacoronavirus ; COVID-19 ; Comorbidity ; Genetic Variation/genetics ; Humans ; Pandemics ; Risk Factors ; SARS-CoV-2
Czasopismo naukowe
Tytuł :
Genetic drug target validation using Mendelian randomisation.
Autorzy :
Schmidt AF; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK. .; UCL BHF Research Accelerator Centre, London, UK. .; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. .
Finan C; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.
Gordillo-Marañón M; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.
Asselbergs FW; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.; Health Data Research UK, 222 Euston Road, London, UK.
Freitag DF; Bayer AG Pharmaceuticals, Open Innovation & Digital Technologies, Aprather Weg 18a, Wuppertal, 42096, Germany.
Patel RS; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.
Tyl B; Center for Therapeutic Innovation, Cardiovascular and Metabolic Disease, Institut de Recherches Internationales Servier, 50 Rue Carnot, 92284, Suresnes Cedex, France.
Chopade S; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.
Faraway R; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.; The Francis Crick Institute, 1 Midland Rd, London, NW1 1AT, UK.
Zwierzyna M; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.
Hingorani AD; Institute of Cardiovascular Science, Faculty of Population Health, University College London, London, WC1E 6BT, UK.; UCL BHF Research Accelerator Centre, London, UK.; Health Data Research UK, 222 Euston Road, London, UK.
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Źródło :
Nature communications [Nat Commun] 2020 Jun 26; Vol. 11 (1), pp. 3255. Date of Electronic Publication: 2020 Jun 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Delivery Systems*
Genes*
Mendelian Randomization Analysis*
Confidence Intervals ; Coronary Disease/genetics ; Genome, Human ; Humans ; Linkage Disequilibrium/genetics ; Lipids/chemistry ; Models, Genetic ; Odds Ratio ; Phenomics ; Polymorphism, Single Nucleotide/genetics ; Proteins/genetics ; Quantitative Trait Loci/genetics ; Reproducibility of Results
Czasopismo naukowe
Tytuł :
Reply to P-F Wu et al.
Autorzy :
Long P; From the Department of Occupational and Environmental Health, Ministry of Education Key Laboratory of Environment and Health, and State Key Laboratory of Environmental Health (Incubating), School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Pan A; Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
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Źródło :
The American journal of clinical nutrition [Am J Clin Nutr] 2020 Jun 01; Vol. 111 (6), pp. 1300-1301.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Coronary Artery Disease*
Mendelian Randomization Analysis*
Asian Continental Ancestry Group ; Folic Acid ; Humans ; Prospective Studies
Czasopismo naukowe
Tytuł :
Application and interpretation of Mendelian randomization approaches in exploring the causality between folate and coronary artery disease.
Autorzy :
Wu PF; From Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.
Zhang W; Department of Neurology, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA.; Department of Biology, College of Arts & Sciences, Boston University, Boston, MA, USA.
Zhang X; Department of Ultrasound Diagnosis, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
Zhang R; Department of Ultrasound Diagnosis, Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
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Źródło :
The American journal of clinical nutrition [Am J Clin Nutr] 2020 Jun 01; Vol. 111 (6), pp. 1299-1300.
Typ publikacji :
Journal Article; Comment
MeSH Terms :
Coronary Artery Disease*
Mendelian Randomization Analysis*
Adult ; Asian Continental Ancestry Group ; Folic Acid ; Humans ; Prospective Studies
Czasopismo naukowe

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