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Tytuł :
Tracheal colonization factor A (TcfA) is a biomarker for rapid and specific detection of Bordetella pertussis.
Autorzy :
Burnham-Marusich AR; DxDiscovery, Reno, NV, USA. .
Olsen RK; DxDiscovery, Reno, NV, USA.; Department of Chemistry, University of Nevada, Reno, Reno, NV, USA.
Scarbrough J; DxDiscovery, Reno, NV, USA.; Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, Reno, NV, USA.; Department of Molecular, Genetic and Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, UK.
Kvam A; Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, Reno, NV, USA.; Charles River Laboratories, Reno, NV, USA.
Yang W; Department of Community Health Sciences, University of Nevada, Reno, Reno, NV, USA.
Zimmerman L; Center for Biological Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Dunn JJ; Texas Children's Hospital, Houston, TX, USA.
Merkel T; Center for Biological Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Kozel TR; DxDiscovery, Reno, NV, USA.; Department of Microbiology and Immunology, University of Nevada, Reno School of Medicine, Reno, NV, USA.
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Źródło :
Scientific reports [Sci Rep] 2020 Sep 14; Vol. 10 (1), pp. 15002. Date of Electronic Publication: 2020 Sep 14.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Bordetella pertussis*/genetics
Bordetella pertussis*/immunology
Bordetella pertussis*/pathogenicity
Bacterial Proteins/*immunology
Biomarkers/*analysis
Immunoassay/*methods
Virulence Factors, Bordetella/*immunology
Whooping Cough/*microbiology
Animals ; Antibodies, Monoclonal/immunology ; Buffers ; Epitope Mapping ; Humans ; Limit of Detection ; Mice ; Nasopharynx/microbiology ; Papio ; Rabbits ; Sensitivity and Specificity ; Whooping Cough/diagnosis
Czasopismo naukowe
Tytuł :
Development and Validation of a Bordetella pertussis Whole-Genome Screening Strategy.
Autorzy :
da Silva Antunes R; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.
Quiambao LG; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.
Sutherland A; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.
Soldevila F; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.
Dhanda SK; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.
Armstrong SK; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Brickman TJ; Department of Microbiology and Immunology, University of Minnesota Medical School, Minneapolis, Minnesota, USA.
Merkel T; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Peters B; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.; University of California San Diego School of Medicine, La Jolla, San Diego, California, USA.
Sette A; Division of Vaccine Discovery, La Jolla Institute for Immunology, La Jolla, San Diego, California, USA.; University of California San Diego School of Medicine, La Jolla, San Diego, California, USA.
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Źródło :
Journal of immunology research [J Immunol Res] 2020 Apr 02; Vol. 2020, pp. 8202067. Date of Electronic Publication: 2020 Apr 02 (Print Publication: 2020).
Typ publikacji :
Journal Article; Validation Study
MeSH Terms :
Bordetella pertussis/*genetics
Bordetella pertussis/*immunology
Pertussis Vaccine/*immunology
Whooping Cough/*immunology
Whooping Cough/*prevention & control
Adult ; Antigens, Bacterial/chemistry ; Antigens, Bacterial/genetics ; Antigens, Bacterial/immunology ; Cytokines/metabolism ; Enzyme-Linked Immunospot Assay ; Epitopes, T-Lymphocyte/chemistry ; Epitopes, T-Lymphocyte/genetics ; Epitopes, T-Lymphocyte/immunology ; Female ; Genome-Wide Association Study ; Humans ; Immunologic Memory ; Male ; Pertussis Vaccine/administration & dosage ; T-Lymphocytes/immunology ; Vaccines, Acellular/administration & dosage ; Vaccines, Acellular/immunology ; Vaccines, Inactivated/administration & dosage ; Vaccines, Inactivated/immunology ; Vaccines, Subunit/chemistry ; Vaccines, Subunit/genetics ; Vaccines, Subunit/immunology
Czasopismo naukowe
Tytuł :
Pertussis vaccines and protective immunity.
Autorzy :
Kapil P; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring MD 20993, USA.
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring MD 20993, USA. Electronic address: tod.merkel@fda.hhs.gov.
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Źródło :
Current opinion in immunology [Curr Opin Immunol] 2019 Aug; Vol. 59, pp. 72-78. Date of Electronic Publication: 2019 May 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.; Review
MeSH Terms :
Bordetella pertussis/*physiology
Pertussis Vaccine/*immunology
Th1 Cells/*immunology
Th17 Cells/*immunology
Whooping Cough/*immunology
Animals ; Antibodies, Bacterial/metabolism ; Child ; Humans ; Immunity, Cellular ; Immunity, Humoral ; Immunologic Memory ; Lymphocyte Activation ; Vaccination ; Vaccines, Acellular
Czasopismo naukowe
Tytuł :
Histopathology of Bordetella pertussis in the Baboon Model.
Autorzy :
Zimmerman LI; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Papin JF; Oklahoma Baboon Research Resource, Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Warfel J; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA.
Wolf RF; Oklahoma Baboon Research Resource, Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Kosanke SD; Oklahoma Baboon Research Resource, Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration, Silver Spring, Maryland, USA tod.merkel@fda.hhs.gov.
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Źródło :
Infection and immunity [Infect Immun] 2018 Oct 25; Vol. 86 (11). Date of Electronic Publication: 2018 Oct 25 (Print Publication: 2018).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Bordetella pertussis/*growth & development
Lung/*pathology
Whooping Cough/*pathology
Animals ; Disease Models, Animal ; Histocytochemistry ; Immunohistochemistry ; Papio ; Trachea/pathology
Czasopismo naukowe
Tytuł :
Activation of Bvg-Repressed Genes in Bordetella pertussis by RisA Requires Cross Talk from Noncooperonic Histidine Kinase RisK.
Autorzy :
Chen Q; Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA .
Ng V; Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
Warfel JM; Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
Merkel TJ; Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
Stibitz S; Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
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Źródło :
Journal of bacteriology [J Bacteriol] 2017 Oct 17; Vol. 199 (22). Date of Electronic Publication: 2017 Oct 17 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Bacterial Proteins/*genetics
Bacterial Proteins/*metabolism
Bordetella pertussis/*genetics
Receptors, Cell Surface/*genetics
Receptors, Cell Surface/*metabolism
Trans-Activators/*metabolism
Bordetella bronchiseptica/genetics ; Bordetella pertussis/metabolism ; Bordetella pertussis/pathogenicity ; Frameshift Mutation ; Genes, Regulator ; Histidine Kinase/metabolism ; Magnesium Sulfate/metabolism ; Mutation ; Phosphorylation ; Promoter Regions, Genetic ; Regulon ; Signal Transduction ; Trans-Activators/genetics ; Virulence
Czasopismo naukowe
Tytuł :
Pertussis disease and transmission and host responses: insights from the baboon model of pertussis.
Autorzy :
Pinto MV; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK. Electronic address: .
Merkel TJ; Laboratory of Respiratory and Special Pathogens, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD, USA. Electronic address: tod.merkel@fda.hhs.gov.
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Źródło :
The Journal of infection [J Infect] 2017 Jun; Vol. 74 Suppl 1, pp. S114-S119.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Models, Animal*
Host-Pathogen Interactions*
Papio*
Bordetella pertussis/*pathogenicity
Whooping Cough/*pathology
Animals ; Bordetella pertussis/immunology ; Pertussis Vaccine/administration & dosage ; Pertussis Vaccine/immunology ; Whooping Cough/immunology
Czasopismo naukowe
Tytuł :
Use of a Toxin Neutralization Assay To Characterize the Serologic Response to Adenylate Cyclase Toxin after Infection with Bordetella pertussis.
Autorzy :
Eby JC; Division of Infectious Diseases, University of Virginia, Charlottesville, Virginia, USA .
Gray MC; Division of Infectious Diseases, University of Virginia, Charlottesville, Virginia, USA.
Warfel JM; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
Hewlett EL; Division of Infectious Diseases, University of Virginia, Charlottesville, Virginia, USA.
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Źródło :
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2017 Jan 05; Vol. 24 (1). Date of Electronic Publication: 2017 Jan 05 (Print Publication: 2017).
Typ publikacji :
Journal Article
MeSH Terms :
Antibody Formation*
Adenylate Cyclase Toxin/*immunology
Bordetella pertussis/*immunology
Neutralization Tests/*methods
Whooping Cough/*immunology
Adolescent ; Adult ; Animals ; Cell Line ; Cell Survival ; Child ; Enzyme-Linked Immunosorbent Assay ; Female ; Humans ; Macrophages/physiology ; Male ; Mice ; Middle Aged ; Papio ; Young Adult
Czasopismo naukowe
Tytuł :
Highlights of the 11th International Bordetella Symposium: from Basic Biology to Vaccine Development.
Autorzy :
Carbonetti NH; University of Maryland School of Medicine, Baltimore, Maryland, USA .
Wirsing von König CH; Labor:Medizin Krefeld MVZ GmbH, Krefeld, Germany.
Lan R; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia.
Jacob-Dubuisson F; Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France.
Cotter PA; University of North Carolina-Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA.
Deora R; Wake Forest School of Medicine, Winston-Salem, North Carolina, USA.
Merkel TJ; Center for Biologics Evaluation and Research, FDA, Silver Spring, Maryland, USA.
van Els CA; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Locht C; Institut Pasteur de Lille, Inserm U1019, CNRS UMR8204, University of Lille, Center for Infection and Immunity of Lille, Lille, France.
Hozbor D; IBBM, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.
Rodriguez ME; CINDEFI (CONICET-UNLP), Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina.
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Źródło :
Clinical and vaccine immunology : CVI [Clin Vaccine Immunol] 2016 Nov 04; Vol. 23 (11), pp. 842-850. Date of Electronic Publication: 2016 Nov 04 (Print Publication: 2016).
Typ publikacji :
Congress
MeSH Terms :
Bordetella pertussis/*immunology
Bordetella pertussis/*physiology
Pertussis Vaccine/*immunology
Whooping Cough/*immunology
Animals ; Argentina/epidemiology ; Bacterial Outer Membrane Proteins/immunology ; Humans ; Infant ; Vaccination ; Virulence Factors, Bordetella/immunology ; Whooping Cough/epidemiology ; Whooping Cough/microbiology
Tytuł :
The multifaceted RisA regulon of Bordetella pertussis.
Autorzy :
Coutte L; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
Huot L; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
Antoine R; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
Slupek S; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
Merkel TJ; Divison of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.
Chen Q; Divison of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.
Stibitz S; Divison of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Silver Spring, MD, USA.
Hot D; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
Locht C; Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Lille, France.; Univ. Lille, Lille, France.; Centre National de la Recherche Scientifique (CNRS), UMR 8204, Lille, France.; Institut National de la Santé et de la Recherche Médicale (Inserm), U1019, Lille, France.
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Źródło :
Scientific reports [Sci Rep] 2016 Sep 13; Vol. 6, pp. 32774. Date of Electronic Publication: 2016 Sep 13.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Regulon*
Bacterial Proteins/*genetics
Bacterial Proteins/*physiology
Bordetella pertussis/*genetics
Receptors, Cell Surface/*genetics
Receptors, Cell Surface/*physiology
Virulence/*genetics
Bordetella pertussis/pathogenicity ; Glutamic Acid/chemistry ; Multigene Family ; Oligonucleotide Array Sequence Analysis ; Operon ; Phosphorylation ; Promoter Regions, Genetic ; Transcription Factors/metabolism ; Transcription, Genetic ; Transcriptional Activation ; Transcriptome
Czasopismo naukowe
Tytuł :
Bordetella pertussis transmission.
Autorzy :
Trainor EA; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA.
Nicholson TL; National Animal Disease Center, Agricultural Research Service, USDA, Ames, IA 50010, USA.
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, MD 20892, USA tod.merkel@fda.hhs.gov.
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Źródło :
Pathogens and disease [Pathog Dis] 2015 Nov; Vol. 73 (8), pp. ftv068. Date of Electronic Publication: 2015 Sep 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Transmission, Infectious*
Bordetella pertussis/*isolation & purification
Whooping Cough/*epidemiology
Whooping Cough/*transmission
Animals ; Bordetella bronchiseptica/isolation & purification ; Bordetella bronchiseptica/physiology ; Bordetella pertussis/physiology ; Disease Models, Animal ; Humans ; Mice ; Papio ; Swine
Czasopismo naukowe
Tytuł :
Maternal and neonatal vaccination protects newborn baboons from pertussis infection.
Autorzy :
Warfel JM; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland.
Papin JF; Oklahoma Baboon Research Resource, Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City.
Wolf RF; Oklahoma Baboon Research Resource, Comparative Medicine, University of Oklahoma Health Sciences Center, Oklahoma City.
Zimmerman LI; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland.
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland.
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2014 Aug 15; Vol. 210 (4), pp. 604-10. Date of Electronic Publication: 2014 Feb 12.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Bordetella pertussis/*immunology
Papio/*immunology
Pertussis Vaccine/*administration & dosage
Whooping Cough/*immunology
Whooping Cough/*prevention & control
Animals ; Animals, Newborn ; Antibodies, Bacterial/immunology ; Female ; Immunization Schedule ; Pertussis Vaccine/immunology ; Pregnancy ; Vaccination/methods
Czasopismo naukowe
Tytuł :
Nonhuman primate and human challenge models of pertussis.
Autorzy :
Merkel TJ; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland.
Halperin SA
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2014 Apr 01; Vol. 209 Suppl 1, pp. S20-3.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Models, Animal*
Bordetella pertussis/*immunology
Pertussis Vaccine/*immunology
Whooping Cough/*immunology
Whooping Cough/*prevention & control
Animals ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/prevention & control ; Humans ; Papio ; Primates ; United States/epidemiology ; Whooping Cough/epidemiology
Czasopismo naukowe
Tytuł :
Pertussis pathogenesis--what we know and what we don't know.
Autorzy :
Hewlett EL; Departments of Medicine and Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, Charlottesville, Virginia.
Burns DL
Cotter PA
Harvill ET
Merkel TJ
Quinn CP
Stibitz ES
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2014 Apr 01; Vol. 209 (7), pp. 982-5.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Review
MeSH Terms :
Bacterial Proteins/*metabolism
Bordetella pertussis/*pathogenicity
Virulence Factors/*metabolism
Whooping Cough/*microbiology
Whooping Cough/*pathology
Animals ; Animals, Newborn ; Disease Models, Animal ; Papio ; Virulence
Czasopismo naukowe
Tytuł :
Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection.
Autorzy :
Eby JC; Division of Infectious Diseases and International Health, Department of Medicine, University of Virginia School of Medicine, Charlottesville, Virginia, USA.
Gray MC
Warfel JM
Paddock CD
Jones TF
Day SR
Bowden J
Poulter MD
Donato GM
Merkel TJ
Hewlett EL
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Źródło :
Infection and immunity [Infect Immun] 2013 May; Vol. 81 (5), pp. 1390-8. Date of Electronic Publication: 2013 Feb 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Adenylate Cyclase Toxin/*analysis
Bordetella pertussis/*enzymology
Nasopharynx/*enzymology
Whooping Cough/*microbiology
Animals ; Bacterial Load ; Bordetella pertussis/isolation & purification ; Cells, Cultured ; Colony Count, Microbial ; Disease Models, Animal ; Female ; Humans ; Infant, Newborn ; Nasopharynx/microbiology ; Papio
Czasopismo naukowe
Tytuł :
Airborne transmission of Bordetella pertussis.
Autorzy :
Warfel JM; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, Bethesda, Maryland 20892, USA.
Beren J
Merkel TJ
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Źródło :
The Journal of infectious diseases [J Infect Dis] 2012 Sep 15; Vol. 206 (6), pp. 902-6. Date of Electronic Publication: 2012 Jul 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Air Microbiology*
Bordetella pertussis/*physiology
Whooping Cough/*microbiology
Whooping Cough/*transmission
Aerosols ; Animals ; Humans ; Leukocytosis ; Papio ; Time Factors
Czasopismo naukowe
Tytuł :
Nonhuman primate model of pertussis.
Autorzy :
Warfel JM; Division of Bacterial, Parasitic and Allergenic Products, Center for Biologics Evaluation and Research, FDA, Bethesda, Maryland, USA.
Beren J
Kelly VK
Lee G
Merkel TJ
Pokaż więcej
Źródło :
Infection and immunity [Infect Immun] 2012 Apr; Vol. 80 (4), pp. 1530-6. Date of Electronic Publication: 2012 Jan 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
MeSH Terms :
Disease Models, Animal*
Macaca mulatta*
Papio*
Whooping Cough*/immunology
Whooping Cough*/prevention & control
Bordetella pertussis/*immunology
Animals ; Antibodies, Bacterial/blood ; Bordetella pertussis/growth & development ; Pertussis Vaccine/immunology
Czasopismo naukowe
Tytuł :
Activation of the vrg6 promoter of Bordetella pertussis by RisA.
Autorzy :
Cróinín TO; Laboratory of Respiratory and Special Pathogens, DBPAP/CBER/FDA, Building 29, Rm. 418, 8800 Rockville Pike, Bethesda, MD 20892, USA.
Grippe VK
Merkel TJ
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Źródło :
Journal of bacteriology [J Bacteriol] 2005 Mar; Vol. 187 (5), pp. 1648-58.
Typ publikacji :
Journal Article
MeSH Terms :
Bacterial Proteins/*genetics
Bacterial Proteins/*physiology
Bordetella pertussis/*metabolism
Gene Expression Regulation, Bacterial/*physiology
Promoter Regions, Genetic/*physiology
Receptors, Cell Surface/*physiology
Bacterial Proteins/biosynthesis ; Base Sequence ; Bordetella pertussis/genetics ; DNA-Binding Proteins/physiology ; Molecular Sequence Data ; Mutation ; Protein Binding ; Transcription Factors/physiology
Czasopismo naukowe
Tytuł :
Analysis of bvgR expression in Bordetella pertussis.
Autorzy :
Merkel TJ; Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland 20892, USA. merkel@cber.fda.gov
Boucher PE
Stibitz S
Grippe VK
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Źródło :
Journal of bacteriology [J Bacteriol] 2003 Dec; Vol. 185 (23), pp. 6902-12.
Typ publikacji :
Journal Article
MeSH Terms :
Gene Expression Regulation, Bacterial*
Genes, Bacterial*
Bacterial Proteins/*genetics
Bordetella pertussis/*genetics
Transcription Factors/*genetics
Bacterial Proteins/metabolism ; Base Sequence ; Bordetella pertussis/pathogenicity ; Humans ; Molecular Sequence Data ; Mutation ; Phosphorylation ; Promoter Regions, Genetic ; Protein Binding ; Signal Transduction/physiology ; Transcription Factors/metabolism ; Transcriptional Activation ; Virulence
Czasopismo naukowe

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