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Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Simoben, Conrad
Robaa, Dina
Chakrabarti, Alokta
Schmidtkunz, Karin
Marek, Martin
Lancelot, Julien
Kannan, Srinivasaraghavan
Melesina, Jelena
Shaik, Tajith
Pierce, Raymond
Romier, Christophe
Jung, Manfred
Sippl, Wolfgang
Pokaż więcej
Temat :
crystal structure
docking
epigenetics
histone deacetylase (HDAC) inhibitors
schistosomiasis
virtual screening
MESH: Animals
MESH: Anthelmintics/pharmacology
MESH: Hydroxamic Acids/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Apoptosis/drug effects
MESH: Molecular Docking Simulation
MESH: Protein Binding
MESH: Protein Interaction Domains and Motifs
MESH: Protein Structure, Secondary
MESH: Pyrrolidines/chemical synthesis
MESH: Pyrrolidines/pharmacology
MESH: Schistosoma mansoni/drug effects
MESH: Helminth Proteins/chemistry
MESH: Schistosoma mansoni/enzymology
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
MESH: Binding Sites
MESH: Structure-Activity Relationship
MESH: Zinc/chemistry
MESH: Zinc/metabolism
MESH: Chelating Agents/chemical synthesis
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
MESH: Helminth Proteins/genetics
MESH: Crystallography, X-Ray
MESH: Gene Expression
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Helminth Proteins/metabolism
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Histone Deacetylase Inhibitors/pharmacology
MESH: Histone Deacetylases/chemistry
MESH: Histone Deacetylases/genetics
MESH: Histone Deacetylases/metabolism
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Źródło :
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Conrad V. Simoben
Dina Robaa
Alokta Chakrabarti
Karin Schmidtkunz
Martin Marek
Julien Lancelot
Srinivasaraghavan Kannan
Jelena Melesina
Tajith B. Shaik
Raymond J. Pierce
Christophe Romier
Manfred Jung
Wolfgang Sippl
Pokaż więcej
Temat :
MESH: Molecular Docking Simulation
MESH: Animals
virtual screening
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
QD241-441
MESH: Schistosoma mansoni/drug effects
MESH: Crystallography, X-Ray
MESH: Histone Deacetylases/genetics
MESH: Pyrrolidines/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Schistosoma mansoni/enzymology
epigenetics
MESH: Helminth Proteins/metabolism
MESH: Binding Sites
MESH: Histone Deacetylase Inhibitors/pharmacology
Organic chemistry
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Zinc/chemistry
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Zinc/metabolism
schistosomiasis
MESH: Hydroxamic Acids/chemical synthesis
histone deacetylase (HDAC) inhibitors
MESH: Protein Interaction Domains and Motifs
MESH: Histone Deacetylases/metabolism
MESH: Protein Structure, Secondary
MESH: Apoptosis/drug effects
MESH: Chelating Agents/chemical synthesis
MESH: Gene Expression
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Article
MESH: Anthelmintics/pharmacology
MESH: Helminth Proteins/genetics
docking
MESH: Protein Binding
MESH: Helminth Proteins/chemistry
MESH: Pyrrolidines/pharmacology
crystal structure
MESH: Histone Deacetylases/chemistry
MESH: Structure-Activity Relationship
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
Źródło :
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 23, Iss 3, p 566 (2018)
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Simoben, Conrad
Robaa, Dina
Chakrabarti, Alokta
Schmidtkunz, Karin
Marek, Martin
Lancelot, Julien
Kannan, Srinivasaraghavan
Melesina, Jelena
Shaik, Tajith
Pierce, Raymond
Romier, Christophe
Jung, Manfred
Sippl, Wolfgang
Pokaż więcej
Temat :
crystal structure
docking
epigenetics
histone deacetylase (HDAC) inhibitors
schistosomiasis
virtual screening
MESH: Animals
MESH: Anthelmintics/pharmacology
MESH: Hydroxamic Acids/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Apoptosis/drug effects
MESH: Molecular Docking Simulation
MESH: Protein Binding
MESH: Protein Interaction Domains and Motifs
MESH: Protein Structure, Secondary
MESH: Pyrrolidines/chemical synthesis
MESH: Pyrrolidines/pharmacology
MESH: Schistosoma mansoni/drug effects
MESH: Helminth Proteins/chemistry
MESH: Schistosoma mansoni/enzymology
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
MESH: Binding Sites
MESH: Structure-Activity Relationship
MESH: Zinc/chemistry
MESH: Zinc/metabolism
MESH: Chelating Agents/chemical synthesis
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
MESH: Helminth Proteins/genetics
MESH: Crystallography, X-Ray
MESH: Gene Expression
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Helminth Proteins/metabolism
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Histone Deacetylase Inhibitors/pharmacology
MESH: Histone Deacetylases/chemistry
MESH: Histone Deacetylases/genetics
MESH: Histone Deacetylases/metabolism
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Źródło :
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing
Autorzy :
Simoben, Conrad
Robaa, Dina
Chakrabarti, Alokta
Schmidtkunz, Karin
Marek, Martin
Lancelot, Julien
Kannan, Srinivasaraghavan
Melesina, Jelena
Shaik, Tajith
Pierce, Raymond
Romier, Christophe
Jung, Manfred
Sippl, Wolfgang
Pokaż więcej
Temat :
crystal structure
docking
epigenetics
histone deacetylase (HDAC) inhibitors
schistosomiasis
virtual screening
MESH: Animals
MESH: Anthelmintics/pharmacology
MESH: Hydroxamic Acids/chemical synthesis
MESH: Hydroxamic Acids/pharmacology
MESH: Apoptosis/drug effects
MESH: Molecular Docking Simulation
MESH: Protein Binding
MESH: Protein Interaction Domains and Motifs
MESH: Protein Structure, Secondary
MESH: Pyrrolidines/chemical synthesis
MESH: Pyrrolidines/pharmacology
MESH: Schistosoma mansoni/drug effects
MESH: Helminth Proteins/chemistry
MESH: Schistosoma mansoni/enzymology
MESH: Schistosoma mansoni/genetics
MESH: Schistosoma mansoni/growth & development
MESH: Binding Sites
MESH: Structure-Activity Relationship
MESH: Zinc/chemistry
MESH: Zinc/metabolism
MESH: Chelating Agents/chemical synthesis
MESH: Anthelmintics/chemical synthesis
MESH: Chelating Agents/pharmacology
MESH: Helminth Proteins/genetics
MESH: Crystallography, X-Ray
MESH: Gene Expression
MESH: Helminth Proteins/antagonists & inhibitors
MESH: Helminth Proteins/metabolism
MESH: Histone Deacetylase Inhibitors/chemical synthesis
MESH: Histone Deacetylase Inhibitors/pharmacology
MESH: Histone Deacetylases/chemistry
MESH: Histone Deacetylases/genetics
MESH: Histone Deacetylases/metabolism
[SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry, Molecular Biology/Biomolecules [q-bio.BM]
Źródło :
Molecules, MDPI, 2018, 23 (3), pp.566. ⟨10.3390/molecules23030566⟩
Tytuł :
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N
Autorzy :
Badreddine, Asmaa
Zarrouk, Amira
Karym, El Mostafa
Debbabi, Meryam
Nury, Thomas
Meddeb, Wiem
Sghaier, Randa
Bezine, Maryem
Vejux, Anne
Martine, Lucy
Grégoire, Stéphane
Bretillon, Lionel
Prost, Emmanuelle
Durand, Philippe
Prost, Michel
Moreau, Thibault
Cherkaoui-Malki, Mustapha
Nasser, Boubker
Lizard, Gérard
Pokaż więcej
Temat :
extra virgin olive oil
alpha-tocopherol
peroxisome
7-ketocholesterol
oxiapoptophagy
158N murine oligodendrocytes
docosahexaenoic acid
mediterranean diet
multiple-sclerosis
lysosome
mitochondria
argan oil
assay interference compounds
polyunsaturated fatty-acids
smooth-muscle-cells
blood-brain-barrier
pear seed oil
alzheimers-disease
MESH: Animals
MESH: Antioxidants/pharmacology
MESH: Oligodendroglia/drug effects
MESH: Oxidative Stress/drug effects
MESH: Peroxisomes/drug effects
MESH: Plant Oils/pharmacology
MESH: alpha-Tocopherol/pharmacology
MESH: Apoptosis/drug effects
MESH: Cell Line
MESH: Ketocholesterols/toxicity
MESH: Lipid Peroxidation
MESH: Lysosomes/drug effects
MESH: Mice
MESH: Mitochondria/drug effects
MESH: Neuroprotective Agents/pharmacology
[SDV.IDA]Life Sciences [q-bio]/Food engineering
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Źródło :
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Tytuł :
Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells
Autorzy :
Brahmi, Fatiha
Hadj-Ahmed, Samia
Zarrouk, Amira
Bezine, Maryem
Nury, Thomas
Madani, Khodir
Chibane, Mohamed
Vejux, Anne
ANDREOLETTI, Pierre
Boulekbache-Makhlouf, Lila
Lizard, Gérard
Pokaż więcej
Temat :
mentha rotundifolia
mitochondria
Mentha spicata
mentha pulegium
MESH: Animals
MESH: Anti-Inflammatory Agents/isolation & purification
MESH: Time Factors
MESH: U937 Cells
MESH: Macrophages/drug effects
MESH: Apoptosis/drug effects
MESH: Autophagy/drug effects
MESH: Caspase 3/metabolism
MESH: Cell Survival/drug effects
MESH: Dose-Response Relationship, Drug
MESH: Humans
MESH: Inhibitory Concentration 50
MESH: Monocytes/metabolism
MESH: Macrophages/metabolism
MESH: Macrophages/pathology
MESH: Membrane Potential, Mitochondrial/drug effects
MESH: Mentha/chemistry
MESH: Mice
MESH: Microtubule-Associated Proteins/metabolism
MESH: Monocytes/drug effects
MESH: Monocytes/pathology
MESH: Anti-Inflammatory Agents/pharmacology
MESH: Phytotherapy
MESH: Plant Extracts/isolation & purification
MESH: Plant Extracts/pharmacology
MESH: Plants, Medicinal
MESH: RAW 264.7 Cells
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
Źródło :
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩
Tytuł :
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N
Autorzy :
Badreddine, Asmaa
Zarrouk, Amira
Karym, El Mostafa
Debbabi, Meryam
Nury, Thomas
Meddeb, Wiem
Sghaier, Randa
Bezine, Maryem
Vejux, Anne
Martine, Lucy
Grégoire, Stéphane
Bretillon, Lionel
Prost, Emmanuelle
Durand, Philippe
Prost, Michel
Moreau, Thibault
Cherkaoui-Malki, Mustapha
Nasser, Boubker
Lizard, Gérard
Pokaż więcej
Temat :
extra virgin olive oil
alpha-tocopherol
peroxisome
7-ketocholesterol
oxiapoptophagy
158N murine oligodendrocytes
docosahexaenoic acid
mediterranean diet
multiple-sclerosis
lysosome
mitochondria
argan oil
assay interference compounds
polyunsaturated fatty-acids
smooth-muscle-cells
blood-brain-barrier
pear seed oil
alzheimers-disease
MESH: Animals
MESH: Antioxidants/pharmacology
MESH: Oligodendroglia/drug effects
MESH: Oxidative Stress/drug effects
MESH: Peroxisomes/drug effects
MESH: Plant Oils/pharmacology
MESH: alpha-Tocopherol/pharmacology
MESH: Apoptosis/drug effects
MESH: Cell Line
MESH: Ketocholesterols/toxicity
MESH: Lipid Peroxidation
MESH: Lysosomes/drug effects
MESH: Mice
MESH: Mitochondria/drug effects
MESH: Neuroprotective Agents/pharmacology
[SDV.IDA]Life Sciences [q-bio]/Food engineering
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Źródło :
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Tytuł :
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N
Autorzy :
Badreddine, Asmaa
Zarrouk, Amira
Karym, El Mostafa
Debbabi, Meryam
Nury, Thomas
Meddeb, Wiem
Sghaier, Randa
Bezine, Maryem
Vejux, Anne
Martine, Lucy
Grégoire, Stéphane
Bretillon, Lionel
Prost, Emmanuelle
Durand, Philippe
Prost, Michel
Moreau, Thibault
Cherkaoui-Malki, Mustapha
Nasser, Boubker
Lizard, Gérard
Pokaż więcej
Temat :
MESH: Animals
blood-brain-barrier
MESH: Lysosomes/drug effects
multiple-sclerosis
alpha-tocopherol
mediterranean diet
MESH: Lipid Peroxidation
extra virgin olive oil
smooth-muscle-cells
argan oil
oxiapoptophagy
MESH: Antioxidants/pharmacology
MESH: Oxidative Stress/drug effects
7-ketocholesterol
docosahexaenoic acid
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
MESH: Mitochondria/drug effects
MESH: Cell Line
alzheimers-disease
[SDV.IDA]Life Sciences [q-bio]/Food engineering
MESH: Neuroprotective Agents/pharmacology
polyunsaturated fatty-acids
mitochondria
pear seed oil
peroxisome
MESH: Plant Oils/pharmacology
MESH: Apoptosis/drug effects
MESH: Oligodendroglia/drug effects
assay interference compounds
MESH: alpha-Tocopherol/pharmacology
MESH: Mice
MESH: Peroxisomes/drug effects
158N murine oligodendrocytes
lysosome
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
MESH: Ketocholesterols/toxicity
Źródło :
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Tytuł :
Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells
Autorzy :
Brahmi, Fatiha
Hadj-Ahmed, Samia
Zarrouk, Amira
Bezine, Maryem
Nury, Thomas
Madani, Khodir
Chibane, Mohamed
Vejux, Anne
ANDREOLETTI, Pierre
Boulekbache-Makhlouf, Lila
Lizard, Gérard
Pokaż więcej
Temat :
MESH: Animals
MESH: Monocytes/metabolism
MESH: Time Factors
MESH: Microtubule-Associated Proteins/metabolism
MESH: Monocytes/drug effects
mentha rotundifolia
MESH: Anti-Inflammatory Agents/pharmacology
MESH: Inhibitory Concentration 50
MESH: Plant Extracts/isolation & purification
MESH: Membrane Potential, Mitochondrial/drug effects
[SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy
MESH: Caspase 3/metabolism
MESH: Cell Survival/drug effects
mitochondria
MESH: Plant Extracts/pharmacology
MESH: Humans
MESH: Macrophages/pathology
MESH: RAW 264.7 Cells
mentha pulegium
MESH: Monocytes/pathology
Mentha spicata
MESH: Dose-Response Relationship, Drug
MESH: Mentha/chemistry
MESH: U937 Cells
MESH: Macrophages/drug effects
MESH: Apoptosis/drug effects
MESH: Mice
MESH: Macrophages/metabolism
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
MESH: Anti-Inflammatory Agents/isolation & purification
MESH: Phytotherapy
MESH: Autophagy/drug effects
MESH: Plants, Medicinal
Źródło :
Pharmaceutical Biology, Taylor & Francis, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩
Tytuł :
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N
Autorzy :
Badreddine, Asmaa
Zarrouk, Amira
Karym, El Mostafa
Debbabi, Meryam
Nury, Thomas
Meddeb, Wiem
Sghaier, Randa
Bezine, Maryem
Vejux, Anne
Martine, Lucy
Grégoire, Stéphane
Bretillon, Lionel
Prost, Emmanuelle
Durand, Philippe
Prost, Michel
Moreau, Thibault
Cherkaoui-Malki, Mustapha
Nasser, Boubker
Lizard, Gérard
Pokaż więcej
Temat :
extra virgin olive oil
alpha-tocopherol
peroxisome
7-ketocholesterol
oxiapoptophagy
158N murine oligodendrocytes
docosahexaenoic acid
mediterranean diet
multiple-sclerosis
lysosome
mitochondria
argan oil
assay interference compounds
polyunsaturated fatty-acids
smooth-muscle-cells
blood-brain-barrier
pear seed oil
alzheimers-disease
MESH: Animals
MESH: Antioxidants/pharmacology
MESH: Oligodendroglia/drug effects
MESH: Oxidative Stress/drug effects
MESH: Peroxisomes/drug effects
MESH: Plant Oils/pharmacology
MESH: alpha-Tocopherol/pharmacology
MESH: Apoptosis/drug effects
MESH: Cell Line
MESH: Ketocholesterols/toxicity
MESH: Lipid Peroxidation
MESH: Lysosomes/drug effects
MESH: Mice
MESH: Mitochondria/drug effects
MESH: Neuroprotective Agents/pharmacology
[SDV.IDA]Life Sciences [q-bio]/Food engineering
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Źródło :
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Tytuł :
Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N
Autorzy :
Badreddine, Asmaa
Zarrouk, Amira
Karym, El Mostafa
Debbabi, Meryam
Nury, Thomas
Meddeb, Wiem
Sghaier, Randa
Bezine, Maryem
Vejux, Anne
Martine, Lucy
Grégoire, Stéphane
Bretillon, Lionel
Prost, Emmanuelle
Durand, Philippe
Prost, Michel
Moreau, Thibault
Cherkaoui-Malki, Mustapha
Nasser, Boubker
Lizard, Gérard
Pokaż więcej
Temat :
extra virgin olive oil
alpha-tocopherol
peroxisome
7-ketocholesterol
oxiapoptophagy
158N murine oligodendrocytes
docosahexaenoic acid
mediterranean diet
multiple-sclerosis
lysosome
mitochondria
argan oil
assay interference compounds
polyunsaturated fatty-acids
smooth-muscle-cells
blood-brain-barrier
pear seed oil
alzheimers-disease
MESH: Animals
MESH: Antioxidants/pharmacology
MESH: Oligodendroglia/drug effects
MESH: Oxidative Stress/drug effects
MESH: Peroxisomes/drug effects
MESH: Plant Oils/pharmacology
MESH: alpha-Tocopherol/pharmacology
MESH: Apoptosis/drug effects
MESH: Cell Line
MESH: Ketocholesterols/toxicity
MESH: Lipid Peroxidation
MESH: Lysosomes/drug effects
MESH: Mice
MESH: Mitochondria/drug effects
MESH: Neuroprotective Agents/pharmacology
[SDV.IDA]Life Sciences [q-bio]/Food engineering
[CHIM.THER]Chemical Sciences/Medicinal Chemistry
[SDV.NEU.NB]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]/Neurobiology
Źródło :
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩
Tytuł :
Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor-induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression
Autorzy :
Zakraoui, Ons
Marcinkiewicz, Cezary
Aloui, Zohra
Othman, Houcemeddine
Grépin, Renaud
Haoues, Meriam
Essafi, Makram
Srairi-Abid, Najet
Gasmi, Ammar
Karoui, Habib
Pagès, Gilles
Essafi-Benkhadir, Khadija
Pokaż więcej
Temat :
MESH: Animals
MESH: Reactive Oxygen Species/metabolism
MESH: Chickens
MESH: Colonic Neoplasms/pathology
MESH: Colon/pathology
[SDV.CAN]Life Sciences [q-bio]/Cancer
MESH: Viper Venoms/therapeutic use
MESH: Neovascularization, Pathologic/metabolism
disintegrin
tumor growth
MESH: Colonic Neoplasms/drug therapy
MESH: Neovascularization, Pathologic/drug therapy
MESH: Neovascularization, Pathologic/pathology
MESH: Colon/metabolism
colon cancer
MESH: Mice, Nude
MESH: Colon/drug effects
Lebein
MESH: Humans
MESH: Antineoplastic Agents/pharmacology
MESH: Apoptosis/drug effects
MESH: Viper Venoms/pharmacology
MESH: Integrin beta1/metabolism
MESH: Models, Molecular
cellular effectors
MESH: Down-Regulation/drug effects
MESH: Neovascularization, Pathologic/genetics
MESH: Cell Proliferation/drug effects
MESH: MAP Kinase Signaling System/drug effects
MESH: Antineoplastic Agents/therapeutic use
[SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology
MESH: Vascular Endothelial Growth Factor A/metabolism
MESH: Colonic Neoplasms/genetics
MESH: Colonic Neoplasms/metabolism
MESH: Vascular Endothelial Growth Factor A/genetics
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
MESH: Cell Cycle Checkpoints/drug effects
MESH: Cell Line, Tumor
Źródło :
Molecular Carcinogenesis, Wiley, 2016, 56, pp.18-35. ⟨10.1002/mc.22470⟩

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