- Tytuł :
-
In vitro-in vivo extrapolation of
metabolic clearance using human liver microsomes: factors showing variability and their normalization. - Autorzy :
- Źródło :
- Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 2020 Sep; Vol. 50 (9), pp. 1064-1075. Date of Electronic Publication: 2020 Mar 12.
- Typ publikacji :
- Journal Article
- MeSH Terms :
-
Metabolic Clearance Rate *
Microsomes, Liver/*physiology
Cytochrome P-450 CYP3A ; Hepatocytes ; Humans ; Kinetics ; Liver ; Midazolam/metabolism -
Czasopismo naukowe