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Wyszukujesz frazę ""Metabolome"" wg kryterium: Temat


Tytuł :
Dynamics of proteo-metabolome from Rubrivivax benzoatilyticus JA2 reveals a programmed switch-off of phototrophic growth, leading to a non-cultivable state as a hyperglycemic effect.
Autorzy :
Gupta D; Department of Plant Sciences, University of Hyderabad, P.O. Central University, Hyderabad 500046, India.
Sasikala C; Bacterial discovery laboratory, Centre for Environment, IST, JNT University Hyderabad, Kukatpally, Hyderabad 500085, India.
Ramana CV; Department of Plant Sciences, University of Hyderabad, P.O. Central University, Hyderabad 500046, India. Electronic address: .
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Źródło :
Journal of proteomics [J Proteomics] 2022 May 30; Vol. 260, pp. 104569. Date of Electronic Publication: 2022 Mar 27.
Typ publikacji :
Journal Article
MeSH Terms :
Burkholderiales*/metabolism
Metabolome*
Phototrophic Processes*
Glucose/metabolism ; Photosynthesis
SCR Organism :
Rubrivivax benzoatilyticus
Czasopismo naukowe
Tytuł :
Evaluating and minimizing batch effects in metabolomics.
Autorzy :
Han W; Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada.
Li L; Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada.
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Źródło :
Mass spectrometry reviews [Mass Spectrom Rev] 2022 May; Vol. 41 (3), pp. 421-442. Date of Electronic Publication: 2020 Nov 25.
Typ publikacji :
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolome*
Metabolomics*/methods
Mass Spectrometry
Czasopismo naukowe
Tytuł :
Dissecting the relationship between plasma and tissue metabolome in a cohort of women with obesity: Analysis of subcutaneous and visceral adipose, muscle, and liver.
Autorzy :
Wu ZE; Food Chemistry and Structure, AgResearch Limited, Palmerston North, New Zealand.; School of Health Sciences, Massey University, Palmerston North, New Zealand.; High-Value Nutrition National Science Challenge, Auckland, New Zealand.
Kruger MC; School of Health Sciences, Massey University, Palmerston North, New Zealand.; Riddet Institute, Massey University, Palmerston North, New Zealand.
Cooper GJS; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Department of Medicine, University of Auckland, Auckland, New Zealand.; Centre for Advanced Discovery and Experimental Therapeutics, School of Medical Sciences, University of Manchester, Manchester, UK.
Sequeira IR; High-Value Nutrition National Science Challenge, Auckland, New Zealand.; School of Biological Sciences, University of Auckland, Auckland, New Zealand.; Human Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
McGill AT; Human Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Poppitt SD; High-Value Nutrition National Science Challenge, Auckland, New Zealand.; Riddet Institute, Massey University, Palmerston North, New Zealand.; Department of Medicine, University of Auckland, Auckland, New Zealand.; Human Nutrition Unit, School of Biological Sciences, University of Auckland, Auckland, New Zealand.
Fraser K; Food Chemistry and Structure, AgResearch Limited, Palmerston North, New Zealand.; High-Value Nutrition National Science Challenge, Auckland, New Zealand.; Riddet Institute, Massey University, Palmerston North, New Zealand.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2022 Jul; Vol. 36 (7), pp. e22371.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolome*
Phosphatidylethanolamines*/metabolism
Biomarkers/metabolism ; Ethers/metabolism ; Female ; Humans ; Liver/metabolism ; Metabolomics/methods ; Muscles/metabolism ; Obesity/metabolism ; Phosphatidylcholines/metabolism ; Triglycerides/metabolism
Czasopismo naukowe
Tytuł :
Integrating metabolome dynamics and process data to guide cell line selection in biopharmaceutical process development.
Autorzy :
Barberi G; CAPE-Lab - Computer-Aided Process Engineering Laboratory, Department of Industrial Engineering, University of Padova, via Marzolo 9, 35131 Padova PD, Italy.
Benedetti A; Process Engineering & Analytics, Medicine Development and Supply, GlaxoSmithKline R&D, Park Rd, Ware SG12 0DP, UK.
Diaz-Fernandez P; Biopharm Process Research, Medicine Development and Supply, GlaxoSmithKline R&D, Gunnels Wood Rd, Stevenage SG1 2NY, UK.
Sévin DC; Omics Science, GlaxoSmithKline R&D, Heidelberg, Germany.
Vappiani J; Omics Science, GlaxoSmithKline R&D, Heidelberg, Germany.
Finka G; Biopharm Process Research, Medicine Development and Supply, GlaxoSmithKline R&D, Gunnels Wood Rd, Stevenage SG1 2NY, UK.
Bezzo F; CAPE-Lab - Computer-Aided Process Engineering Laboratory, Department of Industrial Engineering, University of Padova, via Marzolo 9, 35131 Padova PD, Italy.
Barolo M; CAPE-Lab - Computer-Aided Process Engineering Laboratory, Department of Industrial Engineering, University of Padova, via Marzolo 9, 35131 Padova PD, Italy.
Facco P; CAPE-Lab - Computer-Aided Process Engineering Laboratory, Department of Industrial Engineering, University of Padova, via Marzolo 9, 35131 Padova PD, Italy. Electronic address: .
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Źródło :
Metabolic engineering [Metab Eng] 2022 Jul; Vol. 72, pp. 353-364. Date of Electronic Publication: 2022 Apr 14.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Biological Products*
Metabolome*
Animals ; Biomarkers ; CHO Cells ; Cricetinae ; Cricetulus
Czasopismo naukowe
Tytuł :
The study of human serum metabolome on the health effects of glyphosate and early warning of potential damage.
Autorzy :
Zhang Q; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Liu X; Department of Occupational Disease, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China.
Gao M; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Li X; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Wang Y; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Chang Y; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Zhang X; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Huo Z; Department of Occupational Disease, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China.
Zhang L; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China.
Shan J; Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatics, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
Zhang F; Department of Occupational Disease, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China. Electronic address: .
Zhu B; Department of Occupational Disease, Jiangsu Provincial Center for Disease Prevention and Control, Nanjing, 210009, China. Electronic address: .
Yao W; School of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, 210023, China; Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Nanjing University of Chinese Medicine, Nanjing, 210023, China. Electronic address: .
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Źródło :
Chemosphere [Chemosphere] 2022 Jul; Vol. 298, pp. 134308. Date of Electronic Publication: 2022 Mar 14.
Typ publikacji :
Journal Article
MeSH Terms :
Glycine*/analogs & derivatives
Glycine*/toxicity
Herbicides*/toxicity
Metabolome*
Biomarkers ; Humans ; Metabolomics
Czasopismo naukowe
Tytuł :
The diversity of quinoa morphological traits and seed metabolic composition.
Autorzy :
Tabatabaei I; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany.; University of Potsdam, Department Molecular Biology, Karl-Liebknecht-Strasse 24-25, Haus 20, 14476, Potsdam, Germany.
Alseekh S; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany.; Center of Plant Systems Biology and Biotechnology (CPSBB), 139 Ruski Blvd., 4000, Plovdiv, Bulgaria.
Shahid M; International Center for Biosaline Agriculture (ICBA), Academic City, Near Zayed University, Dubai, United Arab Emirates.
Leniak E; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany.
Wagner M; Boyce Thompson Institute, 533 Tower Rd., Ithaca, NY, 14853, USA.
Mahmoudi H; International Center for Biosaline Agriculture (ICBA), Academic City, Near Zayed University, Dubai, United Arab Emirates.
Thushar S; International Center for Biosaline Agriculture (ICBA), Academic City, Near Zayed University, Dubai, United Arab Emirates.
Fernie AR; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany.; Center of Plant Systems Biology and Biotechnology (CPSBB), 139 Ruski Blvd., 4000, Plovdiv, Bulgaria.
Murphy KM; Washington State University, Sustainable Seed Systems Lab, 273 Johnson Hall, PO Box 646420, Pullman, WA, 99164-6420, USA.
Schmöckel SM; Department Physiology of Yield Stability, Institute of Crop Science, University of Hohenheim, Fruwirthstr. 21, 70599, Stuttgart, Germany.
Tester M; King Abdullah University of Science and Technology (KAUST), Division of Biological and Environmental Sciences and Engineering, Thuwal, Saudi Arabia.
Mueller-Roeber B; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany.; University of Potsdam, Department Molecular Biology, Karl-Liebknecht-Strasse 24-25, Haus 20, 14476, Potsdam, Germany.; Center of Plant Systems Biology and Biotechnology (CPSBB), 139 Ruski Blvd., 4000, Plovdiv, Bulgaria.
Skirycz A; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany. .; Boyce Thompson Institute, 533 Tower Rd., Ithaca, NY, 14853, USA. .
Balazadeh S; Max Planck Institute of Molecular Plant Physiology (MPI-MP), Am Muehlenberg 1, 14476, Potsdam, Germany. .; Institute of Biology, Leiden University, Sylviusweg 72, 2333 BE, Leiden, The Netherlands. .
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Źródło :
Scientific data [Sci Data] 2022 Jun 20; Vol. 9 (1), pp. 323. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji :
Dataset; Journal Article
MeSH Terms :
Chenopodium quinoa*/chemistry
Chenopodium quinoa*/genetics
Chenopodium quinoa*/metabolism
Metabolome*
Seeds*/chemistry
Seeds*/metabolism
Droughts ; Plant Breeding ; Saponins
Czasopismo naukowe
Tytuł :
Small-molecule metabolome identifies potential therapeutic targets against COVID-19.
Autorzy :
Bennet S; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Kaufmann M; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Takami K; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Sjaarda C; Department of Psychiatry, Queen's University, Kingston, ON, Canada.
Douchant K; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Moslinger E; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada.
Wong H; Division of Microbiology, Kingston Health Sciences Centre, Kingston, ON, Canada.
Reed DE; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Ellis AK; Division of Allergy and Immunology, Department of Medicine, Queen's University, Kingston, ON, Canada.
Vanner S; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada.
Colautti RI; Department of Biology, Queen's University, Kingston, ON, Canada.
Sheth PM; Gastrointestinal Diseases Research Unit (GIDRU), Kingston Health Sciences Centre, 76 Stuart St., Kingston, ON, K7L 2V7, Canada. .; Division of Microbiology, Kingston Health Sciences Centre, Kingston, ON, Canada. .; Department of Pathology and Molecular Medicine, Queen's University, Kingston, ON, Canada. .
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Źródło :
Scientific reports [Sci Rep] 2022 Jun 15; Vol. 12 (1), pp. 10029. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/drug therapy
COVID-19*/metabolism
Lysophosphatidylcholines*/metabolism
Metabolome*
Carnosine/metabolism ; Chromatography, Liquid ; Humans ; Influenza, Human ; Respiratory Syncytial Virus Infections ; Respiratory Syncytial Virus, Human ; SARS-CoV-2/metabolism ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Sex differences in the human metabolome.
Autorzy :
Costanzo M; Department of Molecular Medicine and Medical Biotechnology, School of Medicine, University of Naples Federico II, 80131, Naples, Italy. .; CEINGE - Biotecnologie Avanzate s.c.ar.l., 80145, Naples, Italy. .
Caterino M; Department of Molecular Medicine and Medical Biotechnology, School of Medicine, University of Naples Federico II, 80131, Naples, Italy.; CEINGE - Biotecnologie Avanzate s.c.ar.l., 80145, Naples, Italy.
Sotgiu G; Clinical Epidemiology and Medical Statistics Unit, Department of Medical, Surgical and Experimental Sciences, University of Sassari, 07100, Sassari, Italy.
Ruoppolo M; Department of Molecular Medicine and Medical Biotechnology, School of Medicine, University of Naples Federico II, 80131, Naples, Italy.; CEINGE - Biotecnologie Avanzate s.c.ar.l., 80145, Naples, Italy.
Franconi F; Laboratory of Sex-Gender Medicine, National Institute of Biostructures and Biosystems, 07100, Sassari, Italy.
Campesi I; Laboratory of Sex-Gender Medicine, National Institute of Biostructures and Biosystems, 07100, Sassari, Italy.; Department of Biomedical Sciences, University of Sassari, 07100, Sassari, Italy.
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Źródło :
Biology of sex differences [Biol Sex Differ] 2022 Jun 15; Vol. 13 (1), pp. 30. Date of Electronic Publication: 2022 Jun 15.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Metabolome*
Sex Characteristics*
Female ; Humans ; Male ; Metabolomics
Czasopismo naukowe
Tytuł :
Systems biology-based analysis of cell-free systems.
Autorzy :
Sridharan H; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive NW, Atlanta, GA, 30332-0100, United States.
Piorino F; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive NW, Atlanta, GA, 30332-0100, United States.
Styczynski MP; School of Chemical & Biomolecular Engineering, Georgia Institute of Technology, 311 Ferst Drive NW, Atlanta, GA, 30332-0100, United States. Electronic address: .
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Źródło :
Current opinion in biotechnology [Curr Opin Biotechnol] 2022 Jun; Vol. 75, pp. 102703. Date of Electronic Publication: 2022 Mar 02.
Typ publikacji :
Journal Article; Review; Research Support, N.I.H., Extramural
MeSH Terms :
Metabolome*
Systems Biology*/methods
Biotechnology ; Cell-Free System/metabolism ; Proteome/metabolism
Czasopismo naukowe
Tytuł :
Effects of dexmedetomidine, propofol, sevoflurane and S-ketamine on the human metabolome: A randomised trial using nuclear magnetic resonance spectroscopy.
Autorzy :
Nummela AJ; From the Department of Peri-operative Services, Intensive Care and Pain Medicine, Turku University Hospital (AJN, LTL, TTL, REK, JMS, KJV, HS), Department of Internal Medicine, Turku University Hospital, Turku (AJN), Turku PET Centre, University of Turku and Turku University Hospital (LTL, HS), Department of Psychology and Speech-Language Pathology and Turku Brain and Mind Center, University of Turku, Turku (REK, KJV, AR), Department of Intensive Care, Tampere University Hospital, Tampere (JWL), Department of Clinical Medicine, Biostatistics, University of Turku and Turku University Hospital, Turku (TJV), Nightingale Health Ltd, Helsinki, Finland (HTK, VA), Department of Cognitive Neuroscience and Philosophy, School of Bioscience, University of Skövde, Skövde, Sweden (KJV, AR), Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital (MN), Individualized Drug Therapy Research Program, Faculty of Medicine, University of Helsinki (MN), Finnish Institute for Health and Welfare (MP), Research Program for Clinical and Molecular Metabolism, Faculty of Medicine, University of Helsinki, Helsinki (MP), and Integrative Physiology and Pharmacology, Institute of Biomedicine, University of Turku, Turku, Finland (HS).
Laaksonen LT
Laitio TT
Kallionpää RE
Långsjö JW
Scheinin JM
Vahlberg TJ
Koskela HT
Aittomäki V
Valli KJ
Revonsuo A
Niemi M
Perola M
Scheinin H
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Źródło :
European journal of anaesthesiology [Eur J Anaesthesiol] 2022 Jun 01; Vol. 39 (6), pp. 521-532. Date of Electronic Publication: 2021 Sep 22.
Typ publikacji :
Clinical Trial, Phase IV; Journal Article; Randomized Controlled Trial
MeSH Terms :
Anesthetics, Inhalation*/adverse effects
Dexmedetomidine*/adverse effects
Metabolome*/drug effects
Methyl Ethers*
Propofol*
Amino Acids ; Fatty Acids ; Glucose ; Glycerides ; Humans ; Ketamine ; Ketone Bodies ; Magnetic Resonance Spectroscopy ; Male ; Phospholipids ; Sevoflurane
Czasopismo naukowe
Tytuł :
Time-related multivariate strategy for the comprehensive evaluation of microbial chemical data.
Autorzy :
Selegato DM; Nucleus of Bioassays, Biosynthesis, and Ecophysiology of Natural Products (NuBBE), Institute of Chemistry, São Paulo State University, Araraquara, SP, Brazil. .; Zimmermann Group, Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), Heidelberg, Germany. .
Freitas TR; Núcleo de Pesquisa em Compostos Bioativos (NPCBio), Instituto de Química, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.
Pivatto M; Núcleo de Pesquisa em Compostos Bioativos (NPCBio), Instituto de Química, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.
Pivatto AD; Núcleo de Pesquisa em Compostos Bioativos (NPCBio), Instituto de Química, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.
Pilon AC; Núcleo de Pesquisa em Produtos Naturais e Sintéticos (NPPNS), Faculdade de Ciências Farmacêuticas de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil.
Castro-Gamboa I; Nucleus of Bioassays, Biosynthesis, and Ecophysiology of Natural Products (NuBBE), Institute of Chemistry, São Paulo State University, Araraquara, SP, Brazil.
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Źródło :
Metabolomics : Official journal of the Metabolomic Society [Metabolomics] 2022 May 24; Vol. 18 (6), pp. 33. Date of Electronic Publication: 2022 May 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolome*
Metabolomics*
Chromatography, Liquid/methods ; Least-Squares Analysis ; Mass Spectrometry/methods
Czasopismo naukowe
Tytuł :
Time-dependent influence of high glucose environment on the metabolism of neuronal immortalized cells.
Autorzy :
Colombaioni L; Consiglio Nazionale delle Ricerche, Istituto di Neuroscienze, via Giuseppe Moruzzi 1, 56124, Pisa, Italy. Electronic address: .
Campanella B; Consiglio Nazionale delle Ricerche, Istituto di Chimica dei Composti Organometallici, via Giuseppe Moruzzi 1, 56124, Pisa, Italy. Electronic address: .
Nieri R; Consiglio Nazionale delle Ricerche, Istituto di Chimica dei Composti Organometallici, via Giuseppe Moruzzi 1, 56124, Pisa, Italy. Electronic address: .
Onor M; Consiglio Nazionale delle Ricerche, Istituto di Chimica dei Composti Organometallici, via Giuseppe Moruzzi 1, 56124, Pisa, Italy. Electronic address: .
Benedetti E; Unità di Ematologia, Dipartimento di Oncologia, Azienda Ospedaliero Universitaria Pisana, via Roma 67, 56100, Pisa, Italy. Electronic address: .
Bramanti E; Consiglio Nazionale delle Ricerche, Istituto di Chimica dei Composti Organometallici, via Giuseppe Moruzzi 1, 56124, Pisa, Italy. Electronic address: .
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Źródło :
Analytical biochemistry [Anal Biochem] 2022 May 15; Vol. 645, pp. 114607. Date of Electronic Publication: 2022 Feb 25.
Typ publikacji :
Journal Article
MeSH Terms :
Hyperglycemia*/metabolism
Metabolome*
Animals ; Gas Chromatography-Mass Spectrometry ; Glucose/metabolism ; Mammals ; Metabolomics/methods ; Neurons/metabolism
Czasopismo naukowe
Tytuł :
Uncovering in vivo biochemical patterns from time-series metabolic dynamics.
Autorzy :
Wu Y; Institute of Bioinformatics, University of Georgia, Athens, GA, United States of America.
Judge MT; Department of Genetics, University of Georgia, Athens, GA, United States of America.
Edison AS; Institute of Bioinformatics, University of Georgia, Athens, GA, United States of America.; Department of Genetics, University of Georgia, Athens, GA, United States of America.; Complex Carbohydrate Research Center, University of Georgia, Athens, GA, United States of America.; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, United States of America.
Arnold J; Institute of Bioinformatics, University of Georgia, Athens, GA, United States of America.; Department of Genetics, University of Georgia, Athens, GA, United States of America.; Department of Statistics, University of Georgia, Athens, GA, United States of America.; Department of Physics and Astronomy, University of Georgia, Athens, GA, United States of America.
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Źródło :
PloS one [PLoS One] 2022 May 12; Vol. 17 (5), pp. e0268394. Date of Electronic Publication: 2022 May 12 (Print Publication: 2022).
Typ publikacji :
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Metabolome*
Metabolomics*/methods
Magnetic Resonance Imaging ; Magnetic Resonance Spectroscopy ; Metabolic Networks and Pathways ; Plant Extracts
Czasopismo naukowe
Tytuł :
Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes.
Autorzy :
Miettinen T; Pain Clinic, Department of Perioperative Medicine, Intensive Care and Pain Medicine, Helsinki University Hospital and SleepWell Research Programme, University of Helsinki, 00014 Helsinki, Finland.
Nieminen AI; Metabolomics Unit, Institute for Molecular Medicine Finland (FIMM), University of Helsinki, 00014 Helsinki, Finland.
Mäntyselkä P; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Finland, and Primary Health Care Unit, Kuopio University Hospital, 70211 Kuopio, Finland.
Kalso E; Pain Clinic, Department of Perioperative Medicine, Intensive Care and Pain Medicine, Helsinki University Hospital and SleepWell Research Programme, University of Helsinki, 00014 Helsinki, Finland.
Lötsch J; Institute of Clinical Pharmacology, Goethe-University, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Germany.; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Theodor-Stern-Kai 7, 60596 Frankfurt am Main, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2022 May 03; Vol. 23 (9). Date of Electronic Publication: 2022 May 03.
Typ publikacji :
Journal Article
MeSH Terms :
Chronic Pain*/genetics
Chronic Pain*/metabolism
Metabolome*
Adenosine Monophosphate/metabolism ; Biomarkers/metabolism ; Cysteine/metabolism ; Female ; Humans ; Machine Learning ; Metabolomics/methods ; Methionine/metabolism ; NAD/metabolism ; Obesity/metabolism ; Phenotype ; Sleep Wake Disorders
Czasopismo naukowe
Tytuł :
Non-targeted metabolomics reveals differences in the gut metabolic profile of the fall armyworm strains when feeding different food sources.
Autorzy :
Oliveira NC; Insect Interactions Laboratory, Department of Entomology and Acarology, Luiz de Queiroz College of Agriculture, University of São Paulo, Piracicaba, São Paulo, Brazil.
Phelan L; Department of Entomology, OARDC, The Ohio State University, Wooster, OH, United States.
Labate CA; Multi-User Proteomics, Metabolomics and Lipidomics Laboratory, Department of Genetics, Luiz de Queiroz College of Agriculture, University of São Paulo, Piracicaba, São Paulo, Brazil.
Cônsoli FL; Insect Interactions Laboratory, Department of Entomology and Acarology, Luiz de Queiroz College of Agriculture, University of São Paulo, Piracicaba, São Paulo, Brazil. Electronic address: .
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Źródło :
Journal of insect physiology [J Insect Physiol] 2022 May-Jun; Vol. 139, pp. 104400. Date of Electronic Publication: 2022 May 19.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolome*
Oryza*
Animals ; Larva ; Metabolomics ; Plants ; Spodoptera/genetics ; Zea mays
Czasopismo naukowe
Tytuł :
Effects of dietary macronutrients on the hepatic transcriptome and serum metabolome in mice.
Autorzy :
Wu Y; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Green CL; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Wang G; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Yang D; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Li L; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Li B; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Wang L; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Li M; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.; Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.
Li J; University of Dali, Dali, Yunnan Province, People's Republic of China.
Xu Y; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Zhang X; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.; Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.
Niu C; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.
Hu S; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.
Togo J; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Mazidi M; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Derous D; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Douglas A; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.
Speakman JR; State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, People's Republic of China.; Institute of Biological and Environmental Sciences, University of Aberdeen, Aberdeen, Scotland, UK.; Shenzhen Key Laboratory of Metabolic Health, Center for Energy Metabolism and Reproduction, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.; CAS Center of Excellence in Animal Evolution and Genetics, Kunming, People's Republic of China.
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Źródło :
Aging cell [Aging Cell] 2022 Apr; Vol. 21 (4), pp. e13585. Date of Electronic Publication: 2022 Mar 10.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Metabolome*
Transcriptome*/genetics
Animals ; Carbohydrates/pharmacology ; Dietary Carbohydrates/metabolism ; Dietary Carbohydrates/pharmacology ; Dietary Fats/pharmacology ; Dietary Proteins/metabolism ; Dietary Proteins/pharmacology ; Energy Intake ; Liver/metabolism ; Mice ; Nutrients
Czasopismo naukowe
Tytuł :
Development and evaluation of a simultaneous strategy for pyrimidine metabolome quantification in multiple biological samples.
Autorzy :
Xu F; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China.
Pang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China.
Nie Q; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China.
Zhang Z; General Surgery Department, Third Hospital, Peking University, Beijing, China.
Ye C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China.
Jiang C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China.
Wang Y; The State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China. Electronic address: .
Liu H; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Peking University, and the Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, China; Center of Basic Medical Research, Institute of Medical Innovation and Research, Third Hospital, Peking University, Beijing, China; Center for Obesity and Metabolic Disease Research, School of Basic Medical Sciences, Peking University, Beijing, China. Electronic address: .
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Źródło :
Food chemistry [Food Chem] 2022 Mar 30; Vol. 373 (Pt A), pp. 131405. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolome*
Tandem Mass Spectrometry*
Chromatography, High Pressure Liquid ; Chromatography, Liquid ; Metabolomics ; Pyrimidines
Czasopismo naukowe
Tytuł :
Untargeted Metabolomics Analysis Revealed the Major Metabolites in the Seeds of four Polygonatum Species.
Autorzy :
Qi J; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Wei J; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Liao D; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Ding Z; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Yao X; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Sun P; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
Li X; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Institute of Medicinal Plants Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing 100193, China.
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Źródło :
Molecules (Basel, Switzerland) [Molecules] 2022 Feb 21; Vol. 27 (4). Date of Electronic Publication: 2022 Feb 21.
Typ publikacji :
Journal Article
MeSH Terms :
Metabolome*
Metabolomics*/methods
Polygonatum/*chemistry
Seeds/*chemistry
Chromatography, High Pressure Liquid ; Computational Biology/methods ; Polygonatum/classification ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization ; Tandem Mass Spectrometry
Czasopismo naukowe
Tytuł :
Strain-level fitness in the gut microbiome is an emergent property of glycans and a single metabolite.
Autorzy :
Park SY; Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Rao C; Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Coyte KZ; Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Kuziel GA; Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA.
Zhang Y; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Huang W; Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Franzosa EA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Weng JK; Whitehead Institute for Biomedical Research, Cambridge, MA, USA; Department of Biology, Massachusetts Institute of Technology, Cambridge, MA, USA.
Huttenhower C; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Rakoff-Nahoum S; Division of Infectious Diseases and Division of Gastroenterology, Department of Pediatrics, Boston Children's Hospital, Boston, MA, USA; Department of Microbiology, Harvard Medical School, Boston, MA, USA; Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address: .
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Źródło :
Cell [Cell] 2022 Feb 03; Vol. 185 (3), pp. 513-529.e21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gastrointestinal Microbiome*/drug effects
Gastrointestinal Microbiome*/genetics
Metabolome*/drug effects
Metabolome*/genetics
Polysaccharides/*metabolism
Acyl Coenzyme A/metabolism ; Amino Acid Sequence ; Amino Acids, Branched-Chain/metabolism ; Bacteroidetes/drug effects ; Bacteroidetes/genetics ; Bacteroidetes/growth & development ; Butyrates/chemistry ; Butyrates/pharmacology ; Coenzyme A-Transferases/chemistry ; Coenzyme A-Transferases/metabolism ; Genetic Variation/drug effects ; Hydrogen-Ion Concentration ; Polymorphism, Single Nucleotide/genetics ; Promoter Regions, Genetic/genetics ; Species Specificity ; Stress, Physiological/drug effects ; Stress, Physiological/genetics ; Transcription, Genetic/drug effects
Czasopismo naukowe

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