Temat: "Methylcholanthrene" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: Inhibitory Effects of 3-Methylcholanthrene Exposure on Porcine Oocyte Maturation.
Autorzy:: Zhang M; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wang X; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Liu Q; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Yan Y; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Xu C; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhu Z; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Wu S; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zuo X; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zong Y; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Li C; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Zhang Y; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.
Cao Z; Anhui Province Key Laboratory of Local Livestock and Poultry, Genetical Resource Conservation and Breeding, College of Animal Science and Technology, Anhui Agricultural University, Hefei 230036, China.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Mar 14; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 14.
Typ publikacji:: Journal Article
MeSH Terms:: Methylcholanthrene*/pharmacology
Oogenesis*
Animals ; Swine ; Oocytes/metabolism ; Oxidative Stress ; Reactive Oxygen Species/metabolism ; Embryonic Development ; In Vitro Oocyte Maturation Techniques

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Skocz do pozycji: 2.

Tytuł:: EMAP II Expression Is Increased on Peripheral Blood Cells from Non-Hodgkin Lymphoma.
Autorzy:: Saber MM; Department of Clinical Pathology, Faculty of Medicine, Minia University, Minia, Egypt.; Pokaż więcej
Źródło:: Journal of immunology research [J Immunol Res] 2022 Sep 12; Vol. 2022, pp. 7219207. Date of Electronic Publication: 2022 Sep 12 (Print Publication: 2022).
Typ publikacji:: Journal Article
MeSH Terms:: Lymphoma, Non-Hodgkin*/pathology
Methylcholanthrene*
Animals ; Cytokines/metabolism ; Humans ; Lactate Dehydrogenases ; Lymphocytes/metabolism ; Mice ; Neoplasm Proteins ; Neoplasm Recurrence, Local ; RNA-Binding Proteins

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Skocz do pozycji: 3.

Tytuł:: Late effects of cutaneous 3-methylcholanthrene exposure on DNA damage-related pleiotropic growth factors and oxidative stress markers in mice.
Autorzy:: Devrim T
Ekici H
Devrim AK
Sozmen M
Senol A
Bozkur KK
Duru O
Yalcin S; Pokaż więcej
Źródło:: Bratislavske lekarske listy [Bratisl Lek Listy] 2020; Vol. 121 (5), pp. 325-330.
Typ publikacji:: Journal Article
MeSH Terms:: DNA Damage*
Methylcholanthrene*/toxicity
Oxidative Stress*
Animals ; Antioxidants ; Biomarkers ; Mice

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Skocz do pozycji: 4.

Tytuł:: AHR and GPER mediate the stimulatory effects induced by 3-methylcholanthrene in breast cancer cells and cancer-associated fibroblasts (CAFs).
Autorzy:: Cirillo F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Cosenza, Rende, Italy.
Lappano R; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Cosenza, Rende, Italy.
Bruno L; Department of Biology, Ecology and Earth Sciences, University of Calabria, 87036, Rende, Italy.
Rizzuti B; CNR-NANOTEC, Licryl-UOS Cosenza and CEMIF. Cal and Department of Physics, University of Calabria, 87036, Rende, Italy.
Grande F; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Cosenza, Rende, Italy.
Guzzi R; CNR-NANOTEC, Licryl-UOS Cosenza and CEMIF. Cal and Department of Physics, University of Calabria, 87036, Rende, Italy.; Molecular Biophysics Laboratory, Department of Physics, University of Calabria, 87036, Rende, Italy.
Briguori S; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Cosenza, Rende, Italy.
Miglietta AM; Regional Hospital Cosenza, 87100, Cosenza, Italy.
Nakajima M; Drug Metabolism and Toxicology, WPI Nano Life Science Institute, Kanazawa University, Kakuma-machi, Kanazawa, 920-1192, Japan.
Di Martino MT; Department of Experimental and Clinical Medicine, Magna Graecia University, 88100, Catanzaro, Italy. .
Maggiolini M; Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036, Cosenza, Rende, Italy. .; Pokaż więcej
Źródło:: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2019 Aug 01; Vol. 38 (1), pp. 335. Date of Electronic Publication: 2019 Aug 01.
Typ publikacji:: Journal Article
MeSH Terms:: Basic Helix-Loop-Helix Transcription Factors/*metabolism
Breast Neoplasms/*metabolism
Cancer-Associated Fibroblasts/*drug effects
Cancer-Associated Fibroblasts/*metabolism
Methylcholanthrene/*pharmacology
Receptors, Aryl Hydrocarbon/*metabolism
Receptors, Estrogen/*metabolism
Receptors, G-Protein-Coupled/*metabolism
Basic Helix-Loop-Helix Transcription Factors/chemistry ; Breast Neoplasms/genetics ; Breast Neoplasms/pathology ; Cancer-Associated Fibroblasts/pathology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cytochrome P-450 CYP1B1/genetics ; Cytochrome P-450 CYP1B1/metabolism ; ErbB Receptors/metabolism ; Extracellular Signal-Regulated MAP Kinases/metabolism ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Methylcholanthrene/chemistry ; Molecular Conformation ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Protein Binding ; Protein Transport ; Receptors, Aryl Hydrocarbon/chemistry ; Receptors, Estrogen/chemistry ; Receptors, G-Protein-Coupled/chemistry ; Signal Transduction/drug effects ; Structure-Activity Relationship

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Skocz do pozycji: 5.

Tytuł:: Increased Expression of Flightless I in Cutaneous Squamous Cell Carcinoma Affects Wnt/β-Catenin Signaling Pathway.
Autorzy:: Yang GN; Future Industries Institute, University of South Australia, Adelaide 5095, Australia.; Center for Cancer Biology, University of South Australia and SA Pathology, Adelaide 5000, Australia.
Strudwick XL; Future Industries Institute, University of South Australia, Adelaide 5095, Australia.
Bonder CS; Center for Cancer Biology, University of South Australia and SA Pathology, Adelaide 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.
Kopecki Z; Future Industries Institute, University of South Australia, Adelaide 5095, Australia.; Clinical and Health Sciences, University of South Australia, Adelaide 5000, Australia.
Cowin AJ; Future Industries Institute, University of South Australia, Adelaide 5095, Australia.; Clinical and Health Sciences, University of South Australia, Adelaide 5000, Australia.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2021 Dec 08; Vol. 22 (24). Date of Electronic Publication: 2021 Dec 08.
Typ publikacji:: Journal Article
MeSH Terms:: Up-Regulation*
Wnt Signaling Pathway*
Carcinoma, Squamous Cell/*genetics
Microfilament Proteins/*genetics
Skin Neoplasms/*genetics
Trans-Activators/*genetics
Animals ; Carcinoma, Squamous Cell/chemically induced ; Cell Line, Tumor ; Cell Proliferation ; Disease Models, Animal ; Female ; Gene Expression Regulation, Neoplastic ; Gene Knockdown Techniques ; Humans ; Methylcholanthrene/adverse effects ; Mice ; Skin Neoplasms/chemically induced

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Skocz do pozycji: 6.

Tytuł:: Metformin alters therapeutic effects in the BALB/c tumor therapy model.
Autorzy:: Meyer FB; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany.
Goebel S; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany.
Spangel SB; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany.
Leovsky C; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany.
Hoelzer D; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany.
Thierbach R; Friedrich-Schiller-Universität Jena, Fakultät für Biowissenschaften, Institut für Ernährungswissenschaften, Abteilung Humanernährung, Jena, Germany. .; Pokaż więcej
Źródło:: BMC cancer [BMC Cancer] 2021 May 28; Vol. 21 (1), pp. 629. Date of Electronic Publication: 2021 May 28.
Typ publikacji:: Journal Article
MeSH Terms:: Antineoplastic Combined Chemotherapy Protocols/*pharmacology
Metformin/*pharmacology
Neoplasms/*drug therapy
Animals ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; BALB 3T3 Cells ; Carcinogens/toxicity ; Cell Survival/drug effects ; Cell Transformation, Neoplastic/chemically induced ; Culture Media/metabolism ; Docetaxel/pharmacology ; Docetaxel/therapeutic use ; Doxorubicin/pharmacology ; Doxorubicin/therapeutic use ; Drug Evaluation, Preclinical ; Drug Interactions ; Fluorouracil/pharmacology ; Fluorouracil/therapeutic use ; Glucose/metabolism ; Humans ; Metformin/therapeutic use ; Methylcholanthrene/toxicity ; Mice ; Mitomycin/pharmacology ; Mitomycin/therapeutic use

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Skocz do pozycji: 7.

Tytuł:: Dehydroepiandrosterone sulfate and cytochrome P450 inducers alleviate fatty liver in male rats fed an orotic acid-supplemented diet.
Autorzy:: Takeuchi K; Department of Drug Metabolism, Drug Safety Research Center, Tokushima Research Institute, Otsuka Pharmaceutical Co., Ltd, 463-10 Kagasuno, Kawauchi-cho, Tokushima 771-0192, Japan; Laboratory of Molecular Life Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan.
Goto H
Ito Y
Sato M
Matsumoto S
Senba T
Yamada H
Umehara K; Pokaż więcej
Źródło:: The Journal of toxicological sciences [J Toxicol Sci] 2015 Apr; Vol. 40 (2), pp. 181-91.
Typ publikacji:: Journal Article
MeSH Terms:: Cytochrome P-450 Enzyme Inducers/*therapeutic use
Cytochrome P-450 Enzyme System/*metabolism
Dehydroepiandrosterone Sulfate/*therapeutic use
Fatty Liver/*chemically induced
Fatty Liver/*drug therapy
Methylcholanthrene/*therapeutic use
Orotic Acid/*adverse effects
Phenobarbital/*therapeutic use
Animals ; Cytochrome P-450 Enzyme Inducers/pharmacology ; Dehydroepiandrosterone Sulfate/pharmacology ; Drug Therapy, Combination ; Fatty Acids/metabolism ; Fatty Liver/enzymology ; Fatty Liver/pathology ; Liver/enzymology ; Liver/pathology ; Male ; Methylcholanthrene/pharmacology ; Orotic Acid/antagonists & inhibitors ; Oxidation-Reduction/drug effects ; Peroxisomes/pathology ; Phenobarbital/pharmacology ; Rats, Sprague-Dawley ; Sirtuin 1/metabolism

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Skocz do pozycji: 8.

Tytuł:: Hydroxysteroid sulfotransferase 2B1 affects gastric epithelial function and carcinogenesis induced by a carcinogenic agent.
Autorzy:: Hong W; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Guo F; Department of General Surgery, Hua'shan Hospital, Fudan University Shanghai Medical College, Shanghai, China.
Yang M; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Xu D; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Zhuang Z; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Niu B; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China.
Bai Q; Department of Pathology, Fudan University Shanghai Cancer Centre, Shanghai, 200032, China. .; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China. .
Li X; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Fudan University, Shanghai, 200032, China. .; Pokaż więcej
Źródło:: Lipids in health and disease [Lipids Health Dis] 2019 Nov 22; Vol. 18 (1), pp. 203. Date of Electronic Publication: 2019 Nov 22.
Typ publikacji:: Journal Article
MeSH Terms:: Gene Expression Regulation, Neoplastic*
Carcinogenesis/*genetics
Phosphatidylinositol 3-Kinases/*genetics
Proto-Oncogene Proteins c-akt/*genetics
Stomach Neoplasms/*genetics
Sulfotransferases/*genetics
Animals ; Base Sequence ; CRISPR-Cas Systems ; Carcinogenesis/drug effects ; Carcinogenesis/metabolism ; Carcinogenesis/pathology ; Cell Line, Tumor ; Cell Proliferation ; Cholesterol/analogs & derivatives ; Cholesterol/metabolism ; Gastric Mucosa/drug effects ; Gastric Mucosa/enzymology ; Gastric Mucosa/pathology ; Gene Editing ; Humans ; Hydroxycholesterols/metabolism ; Methylcholanthrene/administration & dosage ; Mice ; Mice, Knockout ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; RNA, Small Interfering/genetics ; RNA, Small Interfering/metabolism ; Signal Transduction ; Stomach Neoplasms/chemically induced ; Stomach Neoplasms/enzymology ; Stomach Neoplasms/mortality ; Sulfotransferases/antagonists & inhibitors ; Sulfotransferases/deficiency ; Survival Analysis

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Skocz do pozycji: 9.

Tytuł:: 3-Methylcholanthrene Induces Chylous Ascites in TCDD-Inducible Poly-ADP-Ribose Polymerase ( Tiparp ) Knockout Mice.
Autorzy:: Cho TE; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Bott D; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Ahmed S; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Hutin D; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Gomez A; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. alvin_v_.
Tamblyn L; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Zhou AC; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Watts TH; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Grant DM; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .
Matthews J; Department of Pharmacology and Toxicology, University of Toronto, Toronto, ON M5S 1A8, Canada. .; Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Sognsvannsveien 9, 0372 Oslo, Norway. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2019 May 10; Vol. 20 (9). Date of Electronic Publication: 2019 May 10.
Typ publikacji:: Journal Article
MeSH Terms:: Chylous Ascites/*chemically induced
Chylous Ascites/*enzymology
Methylcholanthrene/*toxicity
Poly(ADP-ribose) Polymerases/*metabolism
Polychlorinated Dibenzodioxins/*toxicity
Adipose Tissue/drug effects ; Adipose Tissue/pathology ; Animals ; Azo Compounds/pharmacology ; Chylous Ascites/pathology ; Cytokines/metabolism ; Fatty Liver/enzymology ; Fatty Liver/pathology ; Gene Expression Regulation, Enzymologic/drug effects ; Inflammation/pathology ; Inflammation Mediators/metabolism ; Liver/drug effects ; Liver/enzymology ; Liver/pathology ; Male ; Mice, Knockout ; Poly(ADP-ribose) Polymerases/genetics ; Pyrazoles/pharmacology ; Receptors, Aryl Hydrocarbon/metabolism ; Signal Transduction ; Survival Analysis

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Skocz do pozycji: 10.

Tytuł:: Simvastatin reduces the carcinogenic effect of 3-methylcholanthrene in renal epithelial cells through histone deacetylase 1 inhibition and RhoA reactivation.
Autorzy:: Chang CC; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Huang KH; National Taiwan University Hospital; Department of Urology, College of Medicine, National Taiwan University; and National Taiwan University Hospital, Taipei, Taiwan.
Hsu SP; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Lee YG; Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Sue YM; Division of Nephrology, Department of Internal Medicine, School of Medicine, College of Medicine and Division of Nephrology, Department of Internal Medicine, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan.
Juan SH; Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. .; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2019 Mar 14; Vol. 9 (1), pp. 4606. Date of Electronic Publication: 2019 Mar 14.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Epithelial Cells/*drug effects
Histone Deacetylase 1/*antagonists & inhibitors
Histone Deacetylase Inhibitors/*pharmacology
Kidney/*drug effects
Methylcholanthrene/*adverse effects
Simvastatin/*pharmacology
rhoA GTP-Binding Protein/*metabolism
Carcinogenesis/chemically induced ; Carcinogenesis/drug effects ; Cells, Cultured ; Epithelial Cells/metabolism ; Epithelial-Mesenchymal Transition/drug effects ; Humans ; Hyaluronan Receptors/metabolism ; Hydroxamic Acids/pharmacology ; Kidney/metabolism ; Receptors, Aryl Hydrocarbon/metabolism

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Skocz do pozycji: 11.

Tytuł:: Pulmonary toxicity and lung tumorigenic potential of surrogate metal oxides in gas metal arc welding-stainless steel fume: Iron as a primary mediator versus chromium and nickel.
Autorzy:: Falcone LM; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.; West Virginia University, School of Medicine, Morgantown, West Virginia, United States of America.
Erdely A; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.; West Virginia University, School of Medicine, Morgantown, West Virginia, United States of America.
Salmen R; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Keane M; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Battelli L; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Kodali V; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Bowers L; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Stefaniak AB; Respiratory Health Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Kashon ML; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Antonini JM; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.
Zeidler-Erdely PC; Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, West Virginia, United States of America.; West Virginia University, School of Medicine, Morgantown, West Virginia, United States of America.; Pokaż więcej
Źródło:: PloS one [PLoS One] 2018 Dec 26; Vol. 13 (12), pp. e0209413. Date of Electronic Publication: 2018 Dec 26 (Print Publication: 2018).
Typ publikacji:: Journal Article
MeSH Terms:: Air Pollutants, Occupational/*toxicity
Carcinogens/*toxicity
Ferric Compounds/*toxicity
Lung Neoplasms/*chemically induced
Welding/*methods
Animals ; Calcium Compounds/toxicity ; Carcinogenesis/chemically induced ; Chromates/toxicity ; Chromium Compounds/toxicity ; Lung/drug effects ; Lung/pathology ; Lung Neoplasms/pathology ; Male ; Methylcholanthrene/toxicity ; Mice ; Nickel/toxicity ; Stainless Steel/chemistry ; Stainless Steel/toxicity

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Skocz do pozycji: 12.

Tytuł:: Squalene is a potential endocrine modulator in rat: A proof-of-principle study with 3-methylcholanthrene-induced toxicity.
Autorzy:: Suriyakalaa U; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.; Department of Microbial Biotechnology, Bharathiar University, Coimbatore, Tamilnadu, India.
Ramachandran R; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.; Department of Microbial Biotechnology, Bharathiar University, Coimbatore, Tamilnadu, India.
Usha K; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.
Sankarganesh D; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.; Department of Biotechnology, School of Bio and Chemical Engineering, Kalasalingam Academy of Research & Education, Krishnankoil, Tamilnadu, India.
Praveenkumar D; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.
Abinaya S; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.
Tirupathi Pichiah PB; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.
Kamalakkannan S; Department of Zoology, Bishop Heber College, Tiruchirappalli, Tamilnadu, India.
Achiraman S; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamilnadu, India.; Pokaż więcej
Źródło:: Andrologia [Andrologia] 2018 Dec; Vol. 50 (10), pp. e13117. Date of Electronic Publication: 2018 Aug 07.
Typ publikacji:: Journal Article
MeSH Terms:: Endocrine Disruptors/*toxicity
Environmental Pollutants/*toxicity
Sex Attractants/*pharmacology
Squalene/*pharmacology
Testis/*drug effects
Animals ; Blood Cell Count ; Epididymis/drug effects ; Liver/drug effects ; Male ; Methylcholanthrene/toxicity ; Models, Animal ; Rats ; Rats, Wistar ; Sperm Count ; Testis/metabolism

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Skocz do pozycji: 13.

Tytuł:: Proteomic analysis of serum in lung cancer induced by 3-methylcholanthrene.
Autorzy:: Li M; Department of Pathology, Medical College, Wuhan University, No.185 Dong-Hu Road, Wuhan 430071, China.
Ye B
Zhang Y
Chen H
Xia D
Liu M
Yang F; Pokaż więcej
Źródło:: Journal of biomedicine & biotechnology [J Biomed Biotechnol] 2009; Vol. 2009, pp. 397910. Date of Electronic Publication: 2009 Sep 24.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Disease Models, Animal*
Methylcholanthrene*
Biomarkers, Tumor/*blood
Lung Neoplasms/*blood
Lung Neoplasms/*chemically induced
Neoplasm Proteins/*blood
Proteome/*analysis
Animals ; Female ; Humans ; Lung Neoplasms/diagnosis ; Male ; Proteomics/methods ; Rats ; Rats, Wistar

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Skocz do pozycji: 14.

Tytuł:: Activation of the dioxin/aryl hydrocarbon receptor (AhR) modulates cell plasticity through a JNK-dependent mechanism.
Autorzy:: Diry M; UMR-S 490 INSERM, UFR Biomédicale des Saints Pères, Paris, Cedex, France.
Tomkiewicz C
Koehle C
Coumoul X
Bock KW
Barouki R
Transy C; Pokaż więcej
Źródło:: Oncogene [Oncogene] 2006 Sep 07; Vol. 25 (40), pp. 5570-4. Date of Electronic Publication: 2006 Apr 17.
Typ publikacji:: Journal Article
MeSH Terms:: JNK Mitogen-Activated Protein Kinases/*metabolism
Methylcholanthrene/*toxicity
Polychlorinated Dibenzodioxins/*metabolism
Receptors, Aryl Hydrocarbon/*metabolism
Actins/metabolism ; Benz(a)Anthracenes/metabolism ; Cadherins/metabolism ; Cell Differentiation ; Cell Line, Tumor ; Cell Movement ; Down-Regulation ; Epithelial Cells/cytology ; Epithelial Cells/metabolism ; Humans ; Ligands ; Methylcholanthrene/metabolism ; Polychlorinated Dibenzodioxins/toxicity ; Receptors, Aryl Hydrocarbon/genetics ; Receptors, Estrogen/metabolism ; Signal Transduction ; Smoke ; Nicotiana

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Skocz do pozycji: 15.

Tytuł:: Characterization of metabolites of benz(j)aceanthrylene in faeces, urine and bile from rat.
Autorzy:: Hegstad S; Department of Environmental Medicine, National Institute of Public Health, Oslo, Norway. />Lundanes E
Holme JA
Alexander J; Pokaż więcej
Źródło:: Xenobiotica; the fate of foreign compounds in biological systems [Xenobiotica] 1999 Dec; Vol. 29 (12), pp. 1257-72.
Typ publikacji:: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Feces*
Bile/*metabolism
Methylcholanthrene/*analogs & derivatives
Mutagens/*metabolism
Animals ; Bile/drug effects ; Biotransformation ; Chromatography, High Pressure Liquid/methods ; Inactivation, Metabolic ; Male ; Mass Spectrometry/methods ; Methylcholanthrene/chemistry ; Methylcholanthrene/metabolism ; Methylcholanthrene/pharmacokinetics ; Mutagens/chemistry ; Mutagens/pharmacokinetics ; Rats ; Rats, Wistar ; Solubility ; Tritium ; Urine ; Water

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Skocz do pozycji: 16.

Tytuł:: Roles of Aryl Hydrocarbon Receptor in Aromatase-Dependent Cell Proliferation in Human Osteoblasts.
Autorzy:: Miki Y; Department of Disaster Obstetrics and Gynecology, International Research Institute of Disaster Science (IRIDeS), Tohoku University, Sendai, Miyagi 980-8575, Japan. .; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan. .; Department of Oral Pathology, Tohoku University Graduate School of Dentistry, Sendai, Miyagi 980-8575, Japan. .
Hata S; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan. .
Ono K; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan. .
Suzuki T; Department of Pathology and Histotechnology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan. .
Ito K; Department of Disaster Obstetrics and Gynecology, International Research Institute of Disaster Science (IRIDeS), Tohoku University, Sendai, Miyagi 980-8575, Japan. .
Kumamoto H; Department of Oral Pathology, Tohoku University Graduate School of Dentistry, Sendai, Miyagi 980-8575, Japan. .
Sasano H; Department of Anatomic Pathology, Tohoku University Graduate School of Medicine, Sendai, Miyagi 980-8575, Japan. .; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2017 Oct 17; Vol. 18 (10). Date of Electronic Publication: 2017 Oct 17.
Typ publikacji:: Journal Article
MeSH Terms:: Aromatase/*metabolism
Osteoblasts/*metabolism
Receptors, Aryl Hydrocarbon/*metabolism
Aromatase/genetics ; Bone and Bones/cytology ; Bone and Bones/metabolism ; Cell Line ; Cell Line, Tumor ; Cell Proliferation ; Cytokines/metabolism ; Estrogens/metabolism ; Gene Expression ; Gene Expression Regulation/drug effects ; Humans ; Immunohistochemistry ; Methylcholanthrene/pharmacology ; Osteoblasts/drug effects ; Osteosarcoma/genetics ; Osteosarcoma/metabolism ; Receptors, Aryl Hydrocarbon/agonists ; Receptors, Aryl Hydrocarbon/genetics ; Signal Transduction/drug effects

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Skocz do pozycji: 17.

Tytuł:: Downregulation of cytochrome P450 2C8 by 3-methylcholanthrene in human hepatocellular carcinoma cell lines.
Autorzy:: Utgikar R; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.
Riddick DS; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.; Department of Pharmacology and Toxicology, Medical Sciences Building, University of Toronto, Toronto, ON M5S 1A8, Canada.; Pokaż więcej
Źródło:: Canadian journal of physiology and pharmacology [Can J Physiol Pharmacol] 2017 Jun; Vol. 95 (6), pp. 768-771. Date of Electronic Publication: 2017 Apr 06.
Typ publikacji:: Journal Article
MeSH Terms:: Carcinoma, Hepatocellular/*pathology
Cytochrome P-450 CYP2C8/*genetics
Down-Regulation/*drug effects
Liver Neoplasms/*pathology
Methylcholanthrene/*pharmacology
Hep G2 Cells ; Humans ; RNA, Messenger/genetics ; RNA, Messenger/metabolism

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Skocz do pozycji: 18.

Tytuł:: Modulating role of pheromonal cues from oestrus-specific urine on 3-methylcholanthrene-induced male reproductive toxicity.
Autorzy:: Suriyakalaa U; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Gayathiri R; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
SankarGanesh D; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Kokilavani P; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Sukirtha R; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Ramachandran R; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.
Kamalakkannan S; Department of Zoology, Bishop Heber College, Tiruchirappalli, Tamil Nadu, India.
Achiraman S; Department of Environmental Biotechnology, Bharathidasan University, Tiruchirappalli, Tamil Nadu, India.; Pokaż więcej
Źródło:: Andrologia [Andrologia] 2016 Sep; Vol. 48 (7), pp. 745-53. Date of Electronic Publication: 2015 Dec 29.
Typ publikacji:: Journal Article
MeSH Terms:: Estrus/*urine
Methylcholanthrene/*toxicity
Reproduction/*drug effects
Sex Attractants/*metabolism
Testis/*drug effects
Testosterone/*blood
Animals ; Cues ; Environmental Pollutants/toxicity ; Female ; Male ; Models, Animal ; Rats ; Rats, Wistar ; Sex Attractants/urine ; Spermatozoa/drug effects

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Skocz do pozycji: 19.

Tytuł:: Activation of liver X receptor inhibits the development of pulmonary carcinomas induced by 3-methylcholanthrene and butylated hydroxytoluene in BALB/c mice.
Autorzy:: Wang Q; Department of Neurosurgery, The General Hospital of Tianjin Medical University, Tianjin, China.; College of Life Sciences, Nankai University, Tianjin, China.
Sun L; College of Life Sciences, Nankai University, Tianjin, China.
Yang X; College of Life Sciences, Nankai University, Tianjin, China.
Ma X; College of Life Sciences, Nankai University, Tianjin, China.
Li Q; College of Life Sciences, Nankai University, Tianjin, China.
Chen Y; College of Biomedical Engineering, Hefei University of Technology, Hefei, China.; School of Medicine, Nankai University, Tianjin, China.
Liu Y; College of Life Sciences, Nankai University, Tianjin, China.
Zhang D; College of Life Sciences, Nankai University, Tianjin, China.
Li X; College of Life Sciences, Nankai University, Tianjin, China.
Xiang R; School of Medicine, Nankai University, Tianjin, China.
Wei Y; Collaborative Innovation Center for Biotherapy, Sichuan University, Chengdu, China.
Han J; College of Biomedical Engineering, Hefei University of Technology, Hefei, China.; The State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and Collaborative Innovation Center for Biotherapy, Nankai University, Tianjin, China.
Duan Y; College of Biomedical Engineering, Hefei University of Technology, Hefei, China.; The State Key Laboratory of Medicinal Chemical Biology, College of Life Sciences and Collaborative Innovation Center for Biotherapy, Nankai University, Tianjin, China.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 Jun 02; Vol. 6, pp. 27295. Date of Electronic Publication: 2016 Jun 02.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Butylated Hydroxytoluene/*administration & dosage
Carcinogens/*administration & dosage
Carcinoma/*prevention & control
Liver X Receptors/*metabolism
Lung Neoplasms/*prevention & control
Methylcholanthrene/*administration & dosage
Animals ; Carcinoma/chemically induced ; Carcinoma/pathology ; Humans ; Interferon-gamma/analysis ; Interferon-gamma/blood ; Lung/pathology ; Lung Neoplasms/chemically induced ; Lung Neoplasms/pathology ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Survival Analysis

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Skocz do pozycji: 20.

Tytuł:: A Microfabricated Platform for Generating Physiologically-Relevant Hepatocyte Zonation.
Autorzy:: McCarty WJ; Center for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children-Boston, Boston, MA, USA.
Usta OB; Center for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children-Boston, Boston, MA, USA.
Yarmush ML; Center for Engineering in Medicine, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, and Shriners Hospitals for Children-Boston, Boston, MA, USA.; Pokaż więcej
Źródło:: Scientific reports [Sci Rep] 2016 May 31; Vol. 6, pp. 26868. Date of Electronic Publication: 2016 May 31.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Cell Culture Techniques/*instrumentation
Cell Culture Techniques/*methods
Hepatocytes/*metabolism
Acetaminophen/metabolism ; Animals ; Cells, Cultured ; Ethanol/metabolism ; Female ; Glucagon/pharmacology ; Glucose/metabolism ; Hepatocytes/drug effects ; Insulin/pharmacology ; Lab-On-A-Chip Devices ; Methylcholanthrene/pharmacology ; Microtechnology ; Nitrogen/metabolism ; Rats, Inbred Lew

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