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    Wyświetlanie 1-9 z 9
    Tytuł:
    Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.
    Autorzy:
    Pino M; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.
    Pereira Ribeiro S; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America.
    Pagliuzza A; Centre de Recherche du CHUM and Department of Microbiology, Infectious Diseases and Immunology, Université de Montréal, QC, Canada.
    Ghneim K; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America.
    Khan A; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.
    Ryan E; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.
    Harper JL; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.
    King CT; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.
    Welbourn S; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Micci L; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.
    Aldrete S; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Delman KA; Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia, United States of America.
    Stuart T; Emory Vaccine Center, Emory University, Hope Clinic, Decatur, Georgia, United States of America.
    Lowe M; Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, Atlanta, Georgia, United States of America.
    Brenchley JM; Barrier Immunity Section, Laboratory of Viral Diseases, National Institutes of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, Maryland, United States of America.
    Derdeyn CA; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America.; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Easley K; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.
    Sekaly RP; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America.
    Chomont N; Centre de Recherche du CHUM and Department of Microbiology, Infectious Diseases and Immunology, Université de Montréal, QC, Canada.
    Paiardini M; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory School of Medicine, Emory University, Atlanta, Georgia, United States of America.
    Marconi VC; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Atlanta, Georgia, United States of America.; Emory Vaccine Center, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Division of Infectious Diseases, Emory University School of Medicine, Atlanta, Georgia, United States of America.; Atlanta Veterans Affairs Medical Center, Atlanta, Georgia, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2021 Aug 27; Vol. 17 (8), pp. e1009825. Date of Electronic Publication: 2021 Aug 27 (Print Publication: 2021).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Homeostasis*
    Anti-Retroviral Agents/*pharmacology
    CD4-Positive T-Lymphocytes/*immunology
    Cytokines/*metabolism
    HIV Infections/*virology
    T-Lymphocyte Subsets/*immunology
    CD4-Positive T-Lymphocytes/drug effects ; CD4-Positive T-Lymphocytes/virology ; DNA, Viral ; Female ; HIV Infections/drug therapy ; HIV Infections/immunology ; HIV-1/immunology ; Humans ; Immunologic Memory/immunology ; Male ; Middle Aged ; T-Lymphocyte Subsets/drug effects ; T-Lymphocyte Subsets/virology ; Viral Load
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence.
    Autorzy:
    Pino M; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Paganini S; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Deleage C; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, United States of America.
    Padhan K; Tissue Analysis Core, Immunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America.
    Harper JL; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    King CT; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Micci L; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Cervasi B; Flow Cytometry Core, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
    Mudd JC; Center for AIDS Research, Department of Medicine, Case Western Reserve University and University Hospitals, Cleveland Medical Center, Cleveland, Ohio, United States of America.
    Gill KP; Flow Cytometry Core, Emory Vaccine Center, Emory University, Atlanta, Georgia, United States of America.
    Jean SM; Division of Animal Resources, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.
    Easley K; Department of Biostatistics and Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.
    Silvestri G; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Estes JD; Vaccine and Gene Therapy Institute at Oregon Health Science Center, Portland, Oregon, United States of America.
    Petrovas C; Tissue Analysis Core, Immunology Laboratory, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, United States of America.
    Lederman MM; Center for AIDS Research, Department of Medicine, Case Western Reserve University and University Hospitals, Cleveland Medical Center, Cleveland, Ohio, United States of America.
    Paiardini M; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Emory University, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2019 Oct 18; Vol. 15 (10), pp. e1008081. Date of Electronic Publication: 2019 Oct 18 (Print Publication: 2019).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Fingolimod Hydrochloride/*therapeutic use
    Immunosuppressive Agents/*therapeutic use
    Lymphopenia/*chemically induced
    Simian Immunodeficiency Virus/*immunology
    T-Lymphocytes, Cytotoxic/*immunology
    T-Lymphocytes, Helper-Inducer/*immunology
    Animals ; Female ; Germinal Center/immunology ; Macaca mulatta ; Simian Acquired Immunodeficiency Syndrome/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC cell levels: a surrogate marker candidate of HIV-induced intestinal damage.
    Autorzy:
    Ploquin MJ; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
    Casrouge A; Institut Pasteur, Unité Immunobiologie des cellules dendritiques, Paris, France.; INSERM U1223, Paris, France.
    Madec Y; Institut Pasteur, URE Epidémiologie des Maladies Emergentes, Paris, France.
    Noël N; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.; Assistance Publique - Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris Sud, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; IDMIT Department, CEA, Université Paris Sud, Inserm U1184, Immunology of viral infections and auto-immune diseases (IMVA), IBFJ, Fontenay-aux-Roses and Kremlin-Bicêtre, France.; Université Paris Sud, Le Kremlin Bicêtre, France.
    Jacquelin B; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
    Huot N; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
    Duffy D; Institut Pasteur, Unité Immunobiologie des cellules dendritiques, Paris, France.; INSERM U1223, Paris, France.
    Jochems SP; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
    Micci L; Emory University School of Medicine and Yerkes National Primate Research Center, Atlanta, Georgia, USA.
    Lécuroux C; IDMIT Department, CEA, Université Paris Sud, Inserm U1184, Immunology of viral infections and auto-immune diseases (IMVA), IBFJ, Fontenay-aux-Roses and Kremlin-Bicêtre, France.
    Boufassa F; INSERM CESP U1018, Université Paris Sud, Le Kremlin-Bicêtre, France.
    Booiman T; Academisch Medisch Centrum, Laboratory of Viral Immune Pathogenesis, Amsterdam, The Netherlands.
    Garcia-Tellez T; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
    Ghislain M; INSERM CESP U1018, Université Paris Sud, Le Kremlin-Bicêtre, France.
    Grand RL; IDMIT Department, CEA, Université Paris Sud, Inserm U1184, Immunology of viral infections and auto-immune diseases (IMVA), IBFJ, Fontenay-aux-Roses and Kremlin-Bicêtre, France.
    Lambotte O; Assistance Publique - Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris Sud, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; IDMIT Department, CEA, Université Paris Sud, Inserm U1184, Immunology of viral infections and auto-immune diseases (IMVA), IBFJ, Fontenay-aux-Roses and Kremlin-Bicêtre, France.; Université Paris Sud, Le Kremlin Bicêtre, France.
    Kootstra N; Academisch Medisch Centrum, Laboratory of Viral Immune Pathogenesis, Amsterdam, The Netherlands.
    Meyer L; Université Paris Sud, Le Kremlin Bicêtre, France.; INSERM CESP U1018, Université Paris Sud, Le Kremlin-Bicêtre, France.
    Goujard C; Assistance Publique - Hôpitaux de Paris, Service de Médecine Interne et Immunologie Clinique, Groupe Hospitalier Universitaire Paris Sud, Hôpital Bicêtre, Le Kremlin-Bicêtre, France.; Université Paris Sud, Le Kremlin Bicêtre, France.; INSERM CESP U1018, Université Paris Sud, Le Kremlin-Bicêtre, France.
    Paiardini M; Emory University School of Medicine and Yerkes National Primate Research Center, Atlanta, Georgia, USA.
    Albert ML; Institut Pasteur, Unité Immunobiologie des cellules dendritiques, Paris, France.
    Müller-Trutwin M; Institut Pasteur, Unité HIV, Inflammation et Persistance, Paris, France.
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    Źródło:
    Journal of the International AIDS Society [J Int AIDS Soc] 2018 Jul; Vol. 21 (7), pp. e25144.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*immunology
    Dipeptidyl Peptidase 4/*blood
    HIV Infections/*enzymology
    Intestinal Diseases/*virology
    Adult ; Animals ; Biomarkers ; CD4 Lymphocyte Count ; Chlorocebus aethiops ; HIV Infections/complications ; HIV Infections/drug therapy ; HIV-1/immunology ; Humans ; Interleukins ; Intestinal Diseases/enzymology ; Intestinal Diseases/immunology ; Intestinal Diseases/pathology ; Macaca ; Male ; Nuclear Receptor Subfamily 1, Group F, Member 3 ; Simian Acquired Immunodeficiency Syndrome/blood ; Th17 Cells/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques.
    Autorzy:
    Ryan ES; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Micci L; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Fromentin R; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Faculty of Medicine, and Centre de Recherche du CHUM, Montreal, Québec, Canada.
    Paganini S; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    McGary CS; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Easley K; Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America.
    Chomont N; Department of Microbiology, Infectiology and Immunology, Université de Montréal, Faculty of Medicine, and Centre de Recherche du CHUM, Montreal, Québec, Canada.
    Paiardini M; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2016 Feb 01; Vol. 12 (2), pp. e1005412. Date of Electronic Publication: 2016 Feb 01 (Print Publication: 2016).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Interleukin-17/*immunology
    Interleukins/*immunology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    Simian Immunodeficiency Virus/*immunology
    Animals ; CD4-Positive T-Lymphocytes/immunology ; Colon/cytology ; Colon/immunology ; Humans ; Immunity, Mucosal ; Inflammation ; Interleukin-17/metabolism ; Interleukins/metabolism ; Longitudinal Studies ; Macaca mulatta ; Rectum/cytology ; Rectum/immunology ; Th17 Cells/immunology ; Viremia ; Interleukin-22
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.
    Autorzy:
    Micci L; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Alvarez X; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
    Iriele RI; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Ortiz AM; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Ryan ES; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    McGary CS; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Deleage C; AIDS Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, Maryland, United States of America.
    McAtee BB; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
    He T; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Apetrei C; Center for Vaccine Research, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
    Easley K; Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Atlanta, Georgia, United States of America.
    Pahwa S; University of Miami Miller School of Medicine, Miami, Florida, United States of America.
    Collman RG; Department of Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America.
    Derdeyn CA; Emory Vaccine Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Davenport MP; Centre for Vascular Research, University of New South Wales, Kensington, New South Wales, Australia.
    Estes JD; AIDS Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research, Inc., Frederick, Maryland, Maryland, United States of America.
    Silvestri G; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Lackner AA; Tulane National Primate Research Center, Tulane University School of Medicine, Covington, Louisiana, United States of America.
    Paiardini M; Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2014 Oct 30; Vol. 10 (10), pp. e1004467. Date of Electronic Publication: 2014 Oct 30 (Print Publication: 2014).
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*virology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    Simian Immunodeficiency Virus/*immunology
    Animals ; CD4-Positive T-Lymphocytes/immunology ; Disease Models, Animal ; Female ; Lymphocyte Depletion ; Macaca mulatta ; Macrophages/immunology ; Macrophages/virology ; Microglia/immunology ; Microglia/virology ; Monocytes/immunology ; Simian Acquired Immunodeficiency Syndrome/virology ; Viral Load ; Viremia
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.
    Autorzy:
    d'Ettorre G; Department of Public Health and Infectious Diseases, Istituto Pasteur - Fondazione Cenci-Bolognetti, University of Rome 'Sapienza', Rome, Italy.
    Baroncelli S; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Rome, Italy.
    Micci L; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America.
    Ceccarelli G; Department of Public Health and Infectious Diseases, Istituto Pasteur - Fondazione Cenci-Bolognetti, University of Rome 'Sapienza', Rome, Italy.
    Andreotti M; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Rome, Italy.
    Sharma P; Division of Pathology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America.
    Fanello G; Department of Emergency Surgery- Emergency Endoscopic Unit, Policlinico Umberto I, University of Rome 'Sapienza', Rome, Italy.
    Fiocca F; Department of Emergency Surgery- Emergency Endoscopic Unit, Policlinico Umberto I, University of Rome 'Sapienza', Rome, Italy.
    Cavallari EN; Department of Public Health and Infectious Diseases, Istituto Pasteur - Fondazione Cenci-Bolognetti, University of Rome 'Sapienza', Rome, Italy.
    Giustini N; Department of Public Health and Infectious Diseases, Istituto Pasteur - Fondazione Cenci-Bolognetti, University of Rome 'Sapienza', Rome, Italy.
    Mallano A; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Rome, Italy.
    Galluzzo CM; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Rome, Italy.
    Vella S; Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, Rome, Italy.
    Mastroianni CM; Infectious Disease Unit, Fondazione Eleonora Lorillard Spencer Cenci, Sapienza University, Latina, Italy.
    Silvestri G; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Paiardini M; Division of Microbiology and Immunology, Yerkes National Primate Research Center, Atlanta, Georgia, United States of America; Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America.
    Vullo V; Department of Public Health and Infectious Diseases, Istituto Pasteur - Fondazione Cenci-Bolognetti, University of Rome 'Sapienza', Rome, Italy.
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    Źródło:
    PloS one [PLoS One] 2014 Oct 23; Vol. 9 (10), pp. e109791. Date of Electronic Publication: 2014 Oct 23 (Print Publication: 2014).
    Typ publikacji:
    Clinical Trial; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antiretroviral Therapy, Highly Active*
    CD4-Positive T-Lymphocytes/*immunology
    HIV Infections/*drug therapy
    HIV Infections/*immunology
    Intestines/*pathology
    Th17 Cells/*immunology
    Adult ; Cell Proliferation ; HIV Infections/blood ; HIV Infections/virology ; Humans ; Immunohistochemistry ; Interferon-gamma/biosynthesis ; Interleukin-17/biosynthesis ; Lipopolysaccharides/blood ; Lymphocyte Activation/immunology ; Male ; Middle Aged ; Viral Load/immunology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21.
    Autorzy:
    Pallikkuth S; University of Miami Miller School of Medicine, Miami, Florida, United States of America.
    Micci L
    Ende ZS
    Iriele RI
    Cervasi B
    Lawson B
    McGary CS
    Rogers KA
    Else JG
    Silvestri G
    Easley K
    Estes JD
    Villinger F
    Pahwa S
    Paiardini M
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (7), pp. e1003471. Date of Electronic Publication: 2013 Jul 04.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    Bacterial Translocation/*drug effects
    Immunity, Mucosal/*drug effects
    Immunoglobulin Fc Fragments/*therapeutic use
    Interleukins/*therapeutic use
    Intestinal Mucosa/*drug effects
    Simian Acquired Immunodeficiency Syndrome/*drug therapy
    Simian Immunodeficiency Virus/*drug effects
    Th17 Cells/*drug effects
    Animals ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Cell Differentiation/drug effects ; Down-Regulation/drug effects ; Female ; Granzymes/biosynthesis ; Granzymes/genetics ; Granzymes/metabolism ; Immunoglobulin Fc Fragments/adverse effects ; Immunoglobulin Fc Fragments/genetics ; Interleukins/adverse effects ; Interleukins/genetics ; Intestinal Mucosa/immunology ; Intestinal Mucosa/pathology ; Intestinal Mucosa/virology ; Macaca mulatta ; Perforin/biosynthesis ; Perforin/genetics ; Perforin/metabolism ; Random Allocation ; Recombinant Fusion Proteins/adverse effects ; Recombinant Fusion Proteins/genetics ; Recombinant Fusion Proteins/therapeutic use ; Simian Acquired Immunodeficiency Syndrome/immunology ; Simian Acquired Immunodeficiency Syndrome/metabolism ; Simian Acquired Immunodeficiency Syndrome/virology ; Simian Immunodeficiency Virus/isolation & purification ; Simian Immunodeficiency Virus/physiology ; Th17 Cells/immunology ; Th17 Cells/pathology ; Th17 Cells/virology ; Up-Regulation/drug effects ; Viral Load/drug effects
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.
    Autorzy:
    Sundaravaradan V; Seattle Biomedical Research Institute, Seattle, Washington, United States of America.
    Saleem R
    Micci L
    Gasper MA
    Ortiz AM
    Else J
    Silvestri G
    Paiardini M
    Aitchison JD
    Sodora DL
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    Źródło:
    PLoS pathogens [PLoS Pathog] 2013; Vol. 9 (6), pp. e1003441. Date of Electronic Publication: 2013 Jun 27.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cytokines/*immunology
    Receptors, Antigen, T-Cell/*immunology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    Simian Immunodeficiency Virus/*immunology
    T-Lymphocytes, Regulatory/*immunology
    Animals ; Cercocebus atys ; Cytokines/blood ; Cytokines/genetics ; Receptors, Antigen, T-Cell/blood ; Receptors, Antigen, T-Cell/genetics ; Simian Acquired Immunodeficiency Syndrome/blood ; Simian Acquired Immunodeficiency Syndrome/genetics ; Simian Immunodeficiency Virus/genetics ; Simian Immunodeficiency Virus/metabolism ; T-Lymphocytes, Regulatory/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Low levels of SIV infection in sooty mangabey central memory CD⁴⁺ T cells are associated with limited CCR5 expression.
    Autorzy:
    Paiardini M; Yerkes National Primate Research Center, Emory Vaccine Center and Department of Pathology, Emory University, Atlanta, Georgia, USA. />Cervasi B
    Reyes-Aviles E
    Micci L
    Ortiz AM
    Chahroudi A
    Vinton C
    Gordon SN
    Bosinger SE
    Francella N
    Hallberg PL
    Cramer E
    Schlub T
    Chan ML
    Riddick NE
    Collman RG
    Apetrei C
    Pandrea I
    Else J
    Munch J
    Kirchhoff F
    Davenport MP
    Brenchley JM
    Silvestri G
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    Źródło:
    Nature medicine [Nat Med] 2011 Jun 26; Vol. 17 (7), pp. 830-6. Date of Electronic Publication: 2011 Jun 26.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural
    MeSH Terms:
    CD4-Positive T-Lymphocytes/*immunology
    Immunologic Memory/*immunology
    Receptors, CCR5/*immunology
    Simian Acquired Immunodeficiency Syndrome/*immunology
    Simian Immunodeficiency Virus/*immunology
    Animals ; CD4-CD8 Ratio ; CD4-Positive T-Lymphocytes/chemistry ; Cercocebus atys/immunology ; Female ; Lymphocyte Activation/immunology ; Macaca mulatta/immunology ; Male ; Receptors, CCR5/analysis ; Receptors, CCR5/metabolism ; Time Factors ; Viral Load/immunology
    Czasopismo naukowe
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