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Tytuł:
Common human genetic variants of APOE impact murine COVID-19 mortality.
Autorzy:
Ostendorf BN; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA. .; Department of Hematology, Oncology, and Tumor Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany. .; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, Berlin, Germany. .; Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine, Berlin, Germany. .
Patel MA; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Bilanovic J; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA.
Hoffmann HH; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Carrasco SE; Laboratory of Comparative Pathology, Weill Cornell Medicine, Memorial Sloan Kettering Cancer Center, and Rockefeller University, New York, NY, USA.
Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, NY, USA.
Tavazoie SF; Laboratory of Systems Cancer Biology, The Rockefeller University, New York, NY, USA. .
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Źródło:
Nature [Nature] 2022 Nov; Vol. 611 (7935), pp. 346-351. Date of Electronic Publication: 2022 Sep 21.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Apolipoproteins E*/genetics
COVID-19*/genetics
COVID-19*/mortality
COVID-19*/virology
Human Genetics*
Mice, Transgenic*/genetics
Mice, Transgenic*/virology
SARS-CoV-2*/pathogenicity
Animals ; Humans ; Male ; Mice ; Apolipoprotein E2/genetics ; Apolipoprotein E3/genetics ; Apolipoprotein E4/genetics ; Prospective Studies ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
An optimized visual loop mediated isothermal amplification assay for efficient detection of minute virus of mice with hydroxynaphthol blue dye.
Autorzy:
Zhang X; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China.
Zhao Y; The Third Outpatient Department, Jinling Hospital, Nanjing 210002, People's Republic of China.
Ma C; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China.
Wu W; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China.
Dong M; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China.
You J; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China.
Liu J; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China. Electronic address: .
Yun S; Department of Comparative Medicine, Jinling Hospital, Nanjing 210002, People's Republic of China; Clinical School of Medical College of Nanjing University, Nanjing 210002, People's Republic of China. Electronic address: .
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Źródło:
Journal of virological methods [J Virol Methods] 2022 Oct; Vol. 308, pp. 114575. Date of Electronic Publication: 2022 Jul 05.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Minute Virus of Mice*
Animals ; Mice ; Molecular Diagnostic Techniques ; Naphthalenesulfonates ; Nucleic Acid Amplification Techniques ; Sensitivity and Specificity
SCR Protocol:
LAMP assay
Czasopismo naukowe
Tytuł:
Development of a humanized HLA-A30 transgenic mouse model.
Autorzy:
Zhu MM; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Niu BW; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Liu LL; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Yang H; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Qin BY; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Peng XH; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Chen LX; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Liu Y; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Wang C; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Ren XN; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Xu CH; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Zhou XH; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
Li F; Department of Laboratory Animal Science, Shanghai Public Health Clinical Center, Shanghai, China.
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Źródło:
Animal models and experimental medicine [Animal Model Exp Med] 2022 Dec; Vol. 5 (4), pp. 350-361. Date of Electronic Publication: 2022 Jul 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
HLA-A Antigens*
Mice, Transgenic*
Animals ; Humans ; Influenza A Virus, H1N1 Subtype ; Mice
Czasopismo naukowe
Tytuł:
Intramembranous bone regeneration in diversity outbred mice is heritable.
Autorzy:
Moran MM; Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, IL, USA; Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA. Electronic address: meghan_.
Ko FC; Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, IL, USA; Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
Mesner LD; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Calabrese GM; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Al-Barghouthi BM; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Farber CR; Center for Public Health Genomics, University of Virginia School of Medicine, Charlottesville, VA, USA; Departments of Public Health Sciences and Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA, USA.
Sumner DR; Department of Anatomy & Cell Biology, Rush University Medical Center, Chicago, IL, USA; Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.
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Źródło:
Bone [Bone] 2022 Nov; Vol. 164, pp. 116524. Date of Electronic Publication: 2022 Aug 24.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Collaborative Cross Mice*/genetics
Genome-Wide Association Study*
Animals ; Bone Density/genetics ; Bone Regeneration/genetics ; Bone and Bones ; Female ; Humans ; Male ; Mice ; Phenotype
Czasopismo naukowe
Tytuł:
Factors affecting robustness of anion exchange chromatography: Selective retention of minute virus of mice using membrane media.
Autorzy:
Chen ST; Department of Chemical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Xu W; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Cai K; AstraZeneca, R&D, Gaithersburg, MD 20878, USA.
Ferreira G; AstraZeneca, R&D, Gaithersburg, MD 20878, USA.
Ranil Wickramasinghe S; Department of Chemical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Qian X; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA. Electronic address: .
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Źródło:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences [J Chromatogr B Analyt Technol Biomed Life Sci] 2022 Nov 01; Vol. 1210, pp. 123449. Date of Electronic Publication: 2022 Sep 13.
Typ publikacji:
Journal Article
MeSH Terms:
Minute Virus of Mice*
Viruses*
Animals ; Anions/chemistry ; Chromatography, Ion Exchange/methods ; Ligands ; Mice ; Serum Albumin, Bovine ; Sodium Chloride
Czasopismo naukowe
Tytuł:
The human EF1a promoter does not provide expression of the transgene in mice.
Autorzy:
Battulin N; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090. .; Institute of Genetic Technologies, Novosibirsk State University, Novosibirsk, Russia, 630090. .
Korablev A; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Ryzhkova A; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Smirnov A; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Kabirova E; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Khabarova A; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Lagunov T; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Serova I; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
Serov O; Laboratory of Developmental Genetics, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia, 630090.
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Źródło:
Transgenic research [Transgenic Res] 2022 Oct; Vol. 31 (4-5), pp. 525-535. Date of Electronic Publication: 2022 Aug 12.
Typ publikacji:
Journal Article
MeSH Terms:
Angiotensin-Converting Enzyme 2*/genetics
Mice, Transgenic*
Animals ; COVID-19 ; Disease Models, Animal ; Humans ; Mice ; Peptide Elongation Factor 1/genetics ; Promoter Regions, Genetic ; SARS-CoV-2/genetics ; Transgenes
Czasopismo naukowe
Tytuł:
Genetic quality: a complex issue for experimental study reproducibility.
Autorzy:
Yoshiki A; Experimental Animal Division, RIKEN BioResource Research Center, Tsukuba, 3050074, Japan. .
Ballard G; Comparative Medicine and Quality, The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Perez AV; Humodigen, Delmar, NY, 12054, USA.
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Źródło:
Transgenic research [Transgenic Res] 2022 Oct; Vol. 31 (4-5), pp. 413-430. Date of Electronic Publication: 2022 Jun 25.
Typ publikacji:
Journal Article; Review; Research Support, Non-U.S. Gov't
MeSH Terms:
Mice, Inbred Strains*
Animals ; Mice ; Mutation ; Reproducibility of Results
Czasopismo naukowe
Tytuł:
QTLViewer: an interactive webtool for genetic analysis in the Collaborative Cross and Diversity Outbred mouse populations.
Autorzy:
Vincent M; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Gerdes Gyuricza I; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Keele GR; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Gatti DM; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706-1544, USA.
Broman KW; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706-1544, USA.
Churchill GA; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2022 Jul 29; Vol. 12 (8).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Collaborative Cross Mice*/genetics
Quantitative Trait Loci*
Animals ; Chromosome Mapping ; Mice ; Phenotype ; Software
Czasopismo naukowe
Tytuł:
Age and diet shape the genetic architecture of body weight in diversity outbred mice.
Autorzy:
Wright KM; Calico Life Sciences LLC, South San Francisco, United States.
Deighan AG; The Jackson Laboratory, Bar Harbor, United States.
Di Francesco A; Calico Life Sciences LLC, South San Francisco, United States.
Freund A; Calico Life Sciences LLC, South San Francisco, United States.
Jojic V; Calico Life Sciences LLC, South San Francisco, United States.
Churchill GA; The Jackson Laboratory, Bar Harbor, United States.
Raj A; Calico Life Sciences LLC, South San Francisco, United States.
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Źródło:
ELife [Elife] 2022 Jul 15; Vol. 11. Date of Electronic Publication: 2022 Jul 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Collaborative Cross Mice*
Diet*
Adult ; Alleles ; Animals ; Body Weight/genetics ; Female ; Genetic Variation ; Genomics ; Humans ; Mice ; Phenotype
Czasopismo naukowe
Tytuł:
A diversity outbred F1 mouse model identifies host-intrinsic genetic regulators of response to immune checkpoint inhibitors.
Autorzy:
Hackett JB; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Glassbrook JE; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.; Department of Biochemistry Microbiology Immunology, Wayne State University, Detroit, MI, USA.
Muñiz MC; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Bross M; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Fielder A; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Dyson G; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
Movahhedin N; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
McCasland J; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
McCarthy-Leo C; Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA.
Gibson HM; Department of Oncology, Karmanos Cancer Institute, Wayne State University, Detroit, MI, USA.
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Źródło:
Oncoimmunology [Oncoimmunology] 2022 Apr 20; Vol. 11 (1), pp. 2064958. Date of Electronic Publication: 2022 Apr 20 (Print Publication: 2022).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Collaborative Cross Mice*
Immune Checkpoint Inhibitors*/pharmacology
Immune Checkpoint Inhibitors*/therapeutic use
Animals ; Genotype ; Mice ; Mice, Inbred C57BL ; Prolactin
Czasopismo naukowe
Tytuł:
Genome-wide association mapping of ethanol sensitivity in the Diversity Outbred mouse population.
Autorzy:
Parker CC; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Philip VM; Center for Computational Sciences, The Jackson Laboratory, Bar Harbor, Maine, USA.
Gatti DM; Center for Computational Sciences, The Jackson Laboratory, Bar Harbor, Maine, USA.
Kasparek S; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Kreuzman AM; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Kuffler L; Center for Mammalian Genetics, The Jackson Laboratory, Bar Harbor, Maine, USA.
Mansky B; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Masneuf S; Laboratory of Behavioral and Genomic Neuroscience, NIAAA, NIH, Rockville, MD, USA.
Sharif K; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Sluys E; Laboratory of Behavioral and Genomic Neuroscience, NIAAA, NIH, Rockville, MD, USA.
Taterra D; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Taylor WM; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Thomas M; Department of Psychology and Program in Neuroscience, Middlebury College, Middlebury, Vermont, USA.
Polesskaya O; Department of Psychiatry, University of California San Diego, La Jolla, California, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, California, USA.
Palmer AA; Department of Psychiatry, University of California San Diego, La Jolla, California, USA.; Institute for Genomic Medicine, University of California San Diego, La Jolla, California, USA.
Holmes A; Laboratory of Behavioral and Genomic Neuroscience, NIAAA, NIH, Rockville, MD, USA.
Chesler EJ; Center for Mammalian Genetics, The Jackson Laboratory, Bar Harbor, Maine, USA.
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Źródło:
Alcoholism, clinical and experimental research [Alcohol Clin Exp Res] 2022 Jun; Vol. 46 (6), pp. 941-960. Date of Electronic Publication: 2022 Apr 17.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Alcoholism*/genetics
Collaborative Cross Mice*/genetics
Animals ; Chromosome Mapping/methods ; Ethanol/pharmacology ; Genome-Wide Association Study ; Male ; Mice ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł:
MoG+: a database of genomic variations across three mouse subspecies for biomedical research.
Autorzy:
Takada T; Integrated Bioresource Information Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan. .
Fukuta K; Center for Genome Informatics, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, 1111 Yata, Mishima, 411-8540, Japan.
Usuda D; Integrated Bioresource Information Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Kushida T; Integrated Bioresource Information Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Kondo S; Center for Genome Informatics, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, 1111 Yata, Mishima, 411-8540, Japan.; Advanced Genomics Center, National Institute of Genetics, 1111 Yata, Mishima, 411-8540, Japan.
Kawamoto S; Genetic Informatics Laboratory, National Institute of Genetics, 1111 Yata, Mishima, 411-8540, Japan.
Yoshiki A; Experimental Animal Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Obata Y; RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan.
Fujiyama A; Center for Genome Informatics, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, 1111 Yata, Mishima, 411-8540, Japan.
Toyoda A; Advanced Genomics Center, National Institute of Genetics, 1111 Yata, Mishima, 411-8540, Japan.; Comparative Genomics Laboratory, National Institute of Genetics, 1111 Yata, Mishima, 411-8540, Japan.
Noguchi H; Center for Genome Informatics, Joint Support-Center for Data Science Research, Research Organization of Information and Systems, 1111 Yata, Mishima, 411-8540, Japan.; Advanced Genomics Center, National Institute of Genetics, 1111 Yata, Mishima, 411-8540, Japan.
Shiroishi T; RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan. .
Masuya H; Integrated Bioresource Information Division, RIKEN BioResource Research Center, 3-1-1 Koyadai, Tsukuba, Ibaraki, 305-0074, Japan. .
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2022 Mar; Vol. 33 (1), pp. 31-43. Date of Electronic Publication: 2021 Nov 15.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Databases, Genetic*
Genome*
Mice, Inbred Strains*/genetics
Animals ; Biomedical Research ; Genomics ; Mice ; Nucleotides
Czasopismo naukowe
Tytuł:
Generation and mutational analysis of a transgenic mouse model of human SRY.
Autorzy:
Thomson E; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
Zhao L; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Chen YS; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Longmuss E; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Ng ET; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Sreenivasan R; Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Croft B; Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Song X; Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
Sinclair A; Murdoch Children's Research Institute and Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.
Weiss M; Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana, USA.
Koopman P; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.
Pelosi E; Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland, Australia.; Centre for Clinical Research, The University of Queensland, Brisbane, Queensland, Australia.
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Źródło:
Human mutation [Hum Mutat] 2022 Mar; Vol. 43 (3), pp. 362-379. Date of Electronic Publication: 2021 Dec 28.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Gene Editing*
Mice, Transgenic*
Sex-Determining Region Y Protein*/genetics
Testis*/metabolism
Animals ; Humans ; Male ; Mice ; Protein Domains
Czasopismo naukowe
Tytuł:
Progress towards completing the mutant mouse null resource.
Autorzy:
Peterson KA; The Jackson Laboratory, Bar Harbor, ME, USA. .
Murray SA; The Jackson Laboratory, Bar Harbor, ME, USA. .
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Źródło:
Mammalian genome : official journal of the International Mammalian Genome Society [Mamm Genome] 2022 Mar; Vol. 33 (1), pp. 123-134. Date of Electronic Publication: 2021 Oct 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Genome*
Mice*/genetics
Animals ; Gene Knockout Techniques ; Mice, Knockout ; Mutagenesis ; Phenotype
Czasopismo naukowe
Tytuł:
Humanized Mouse Models of Systemic Lupus Erythematosus: Opportunities and Challenges.
Autorzy:
Chen J; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Liao S; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Zhou H; Zhanjiang Central Hospital, Guangdong Medical University, Zhanjiang, China.
Yang L; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Guo F; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Chen S; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Li A; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Pan Q; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Yang C; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Liu HF; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
Pan Q; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, China.
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Źródło:
Frontiers in immunology [Front Immunol] 2022 Jan 18; Vol. 12, pp. 816956. Date of Electronic Publication: 2022 Jan 18 (Print Publication: 2021).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Disease Models, Animal*
Mice, Transgenic*
Lupus Erythematosus, Systemic/*etiology
Lupus Erythematosus, Systemic/*metabolism
Animals ; Autoantibodies/immunology ; Autoantigens/immunology ; Autoimmune Diseases ; Autoimmunity ; Biomarkers ; Disease Management ; Disease Susceptibility/immunology ; Humans ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/therapy ; Mice
Czasopismo naukowe
Tytuł:
TRAPing Ghrelin-Activated Circuits: A Novel Tool to Identify, Target and Control Hormone-Responsive Populations in TRAP2 Mice.
Autorzy:
Stoltenborg I; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Peris-Sampedro F; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Schéle E; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Le May MV; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
Adan RAH; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.; Department of Translational Neuroscience, Brain Center Rudolf Magnus, University Medical Center Utrecht and Utrecht University, 3584 CJ Utrecht, The Netherlands.
Dickson SL; Department of Physiology/Endocrine, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, 405 30 Gothenburg, Sweden.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Jan 05; Vol. 23 (1). Date of Electronic Publication: 2022 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Gene Expression Regulation*/drug effects
Mice, Transgenic*
Ghrelin/*metabolism
Receptors, Ghrelin/*genetics
Animals ; Eating ; Female ; Food Preferences ; Gene Order ; Gene Targeting/methods ; Genetic Vectors/genetics ; Ghrelin/pharmacology ; Homologous Recombination ; Male ; Mice ; Neurons/metabolism ; Phenotype ; Receptors, Ghrelin/metabolism ; Sex Factors ; Transcriptional Activation
Czasopismo naukowe
Tytuł:
Toward pharmacogenetic SLCO1B1-guided dosing of methotrexate in arthritis using a murine Slco1b2 knockout model.
Autorzy:
Taylor ZL; Department of Pharmacology and Systems Physiology, University of Cincinnati, Cincinnati, Ohio, USA.; Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Thompson LE; Department of Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Bear H; Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
Mizuno T; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Vinks AA; Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Ramsey LB; Division of Research in Patient Services, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Division of Clinical Pharmacology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
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Źródło:
Clinical and translational science [Clin Transl Sci] 2021 Nov; Vol. 14 (6), pp. 2267-2277. Date of Electronic Publication: 2021 Jun 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Liver-Specific Organic Anion Transporter 1*
Mice, Knockout*
Pharmacogenomic Testing*
Antirheumatic Agents/*administration & dosage
Arthritis/*drug therapy
Methotrexate/*administration & dosage
Animals ; Antirheumatic Agents/pharmacology ; Collagen/drug effects ; Collagen/metabolism ; Genotype ; Humans ; Male ; Methotrexate/pharmacology ; Mice ; Pharmacogenetics
Czasopismo naukowe
Tytuł:
Identification of sample mix-ups and mixtures in microbiome data in Diversity Outbred mice.
Autorzy:
Lobo AK; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.
Traeger LL; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Keller MP; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Attie AD; Department of Biochemistry, University of Wisconsin-Madison, Madison, WI 53706, USA.
Rey FE; Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
Broman KW; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI 53706, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 Oct 19; Vol. 11 (11).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Collaborative Cross Mice*
Microbiota*/genetics
Animals ; Genotype ; Mice ; Quantitative Trait Loci
Czasopismo naukowe
Tytuł:
A systems approach using Diversity Outbred mice distinguishes the cardiovascular effects and genetics of circulating GDF11 from those of its homolog, myostatin.
Autorzy:
Starcher AE; Department of Nutritional Sciences, University of Georgia, Athens, GA 30602, USA.
Peissig K; Department of Nutritional Sciences, University of Georgia, Athens, GA 30602, USA.
Stanton JB; Department of Pathology, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Churchill GA; The Jackson Laboratory, Bar Harbor, ME 04609, USA.
Cai D; Department of Physiology, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Maxwell JT; Department of Pediatrics, Emory School of Medicine, Atlanta, GA 30322, USA.
Grider A; Department of Nutritional Sciences, University of Georgia, Athens, GA 30602, USA.
Love K; K. R. Love Quantitative Consulting and Collaboration, Athens, GA 30605, USA.
Chen SY; Department of Physiology, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Coleman AE; Department of Small Animal Medicine & Surgery, University of Georgia College of Veterinary Medicine, Athens, GA 30602, USA.
Strauss E; Department of Nutritional Sciences, University of Georgia, Athens, GA 30602, USA.
Pazdro R; Department of Nutritional Sciences, University of Georgia, Athens, GA 30602, USA.
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Źródło:
G3 (Bethesda, Md.) [G3 (Bethesda)] 2021 Oct 19; Vol. 11 (11).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Collaborative Cross Mice*
Myostatin*/genetics
Animals ; Bone Morphogenetic Proteins/genetics ; Growth Differentiation Factors/genetics ; Mice ; Systems Analysis ; Transforming Growth Factor beta
Czasopismo naukowe
Tytuł:
A Tendon-Specific Double Reporter Transgenic Mouse Enables Tracking Cell Lineage and Functions Alteration In Vitro and In Vivo.
Autorzy:
Chen R; Department of Neuroanatomy, Group for Regeneration and Reprogramming, Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
Zhou X; Department of Neuroanatomy, Group for Regeneration and Reprogramming, Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
Skutella T; Department of Neuroanatomy, Group for Regeneration and Reprogramming, Institute for Anatomy and Cell Biology, Medical Faculty, Heidelberg University, 69120 Heidelberg, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 17; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 17.
Typ publikacji:
Journal Article
MeSH Terms:
Mice, Transgenic*
Promoter Regions, Genetic*
Basic Helix-Loop-Helix Transcription Factors/*genetics
Collagen Type I, alpha 1 Chain/*genetics
Tendons/*metabolism
Animals ; Cell Tracking ; Mesenchymal Stem Cells ; Mice ; Tendons/growth & development ; Tendons/physiology
Czasopismo naukowe

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