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Tytuł:
Role of TRPC3 in Right Ventricular Dilatation under Chronic Intermittent Hypoxia in 129/SvEv Mice.
Autorzy:
Park DY; Department of Otolaryngology, Ajou University School of Medicine, Suwon 16499, Republic of Korea.
Heo W; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kang M; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Ahn T; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kim D; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Choi A; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Birnbaumer L; Laboratory of Signal Transduction, National Institute of Environmental Health Sciences, Research Triangle Park, Durham, NC 27709, USA.; Institute of Biomedical Research (BIOMED), Catholic University of Argentina, Buenos Aires C1107AFF, Argentina.
Cho HJ; Department of Otorhinolaryngology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.; The Airway Mucus Institute, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
Kim JY; Department of Pharmacology, Yonsei University College of Medicine, Seoul 03722, Republic of Korea.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Jul 10; Vol. 24 (14). Date of Electronic Publication: 2023 Jul 10.
Typ publikacji:
Journal Article
MeSH Terms:
Hypertension, Pulmonary*/complications
Hypertension, Pulmonary*/genetics
Hypertrophy, Right Ventricular*/etiology
Hypertrophy, Right Ventricular*/genetics
Sleep Apnea, Obstructive*/metabolism
Animals ; Mice ; Chronic Disease ; Endothelins ; Hypoxia/complications ; Hypoxia/genetics ; Hypoxia/metabolism ; Mice, 129 Strain ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models.
Autorzy:
Lambouras M; Breast Cancer Risk and Prevention Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia.; Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC 3800, Australia.
Roelofs C; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084, Australia.
Pereira M; Breast Cancer Risk and Prevention Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia.
Gruber E; The Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
Vieusseux JL; Breast Cancer Risk and Prevention Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia.
Lanteri P; Breast Cancer Risk and Prevention Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
Johnstone CN; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, VIC 3084, Australia.
Muntz F; The Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.
O'Toole S; Sydney Medical School, University of Sydney, Camperdown, NSW 2050, Australia.; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; Australian Clinical Labs, Sydney, NSW 2153, Australia.
Ooms LM; Cancer Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Mitchell CA; Cancer Program, Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia.
Anderson RL; Olivia Newton-John Cancer Research Institute, Heidelberg, VIC 3084, Australia.; The Peter MacCallum Cancer Centre, Melbourne, VIC 3000, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.; School of Cancer Medicine, La Trobe University, Heidelberg, VIC 3084, Australia.
Britt KL; Breast Cancer Risk and Prevention Laboratory, Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC 3000, Australia.; Department of Anatomy and Developmental Biology, Monash University, Clayton, VIC 3800, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC 3000, Australia.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2023 Mar 16; Vol. 24 (6). Date of Electronic Publication: 2023 Mar 16.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Breast Neoplasms*/genetics
Receptors, Estrogen*/genetics
Tamoxifen*/pharmacology
Humans ; Cell Line, Tumor ; Animals ; Mice ; Disease Models, Animal ; Phenotype ; Immunohistochemistry ; Flow Cytometry ; Transcriptome ; Mice, 129 Strain ; RNA-Seq ; Epithelial Cells ; Mammary Glands, Animal/cytology ; Mammary Neoplasms, Experimental/drug therapy ; Mammary Neoplasms, Experimental/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Differences in Diurnal Rhythm of Rod Outer Segment Renewal between 129T2/SvEmsJ and C57BL/6J Mice.
Autorzy:
Vargas JA; Center for Cancer, Genetic Diseases and Gene Regulation, Department of Biological Sciences, Fordham University, Bronx, NY 10458, USA.
Finnemann SC; Center for Cancer, Genetic Diseases and Gene Regulation, Department of Biological Sciences, Fordham University, Bronx, NY 10458, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2022 Aug 22; Vol. 23 (16). Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Circadian Rhythm*/physiology
Rod Cell Outer Segment*/physiology
Animals ; Mammals ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Phagocytosis/physiology ; Phagosomes ; Phosphatidylserines ; Retinal Pigment Epithelium/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Regulation of gene expression by the APP family in the adult cerebral cortex.
Autorzy:
Cha HJ; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute (DFCI), Harvard Stem Cell Institute, Harvard Medical School, Boston, MA, 02115, USA.
Shen J; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA.; Program in Neuroscience, Harvard Medical School, Boston, MA, 02115, USA.
Kang J; Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Jan 07; Vol. 12 (1), pp. 66. Date of Electronic Publication: 2022 Jan 07.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Amyloid beta-Protein Precursor/*metabolism
Cerebral Cortex/*metabolism
Amyloid beta-Protein Precursor/genetics ; Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Databases, Genetic ; Female ; Gene Expression Regulation ; Male ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Neprilysin/genetics ; Neprilysin/metabolism ; Transcription, Genetic ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Tianeptine, but not fluoxetine, decreases avoidant behavior in a mouse model of early developmental exposure to fluoxetine.
Autorzy:
Pekarskaya EA; Department of Neuroscience, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA.; Division of Molecular Therapeutics, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.
Holt ES; Division of Molecular Therapeutics, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.; Division of Developmental Neuroscience, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.
Gingrich JA; Division of Developmental Neuroscience, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.; Sackler Institute for Developmental Psychobiology, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.
Ansorge MS; Division of Developmental Neuroscience, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.; Sackler Institute for Developmental Psychobiology, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA.
Javitch JA; Division of Molecular Therapeutics, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA. .; Department of Molecular Pharmacology and Therapeutics, Columbia University Vagelos College of Physicians and Surgeons, New York, NY, USA. .
Canetta SE; Division of Molecular Therapeutics, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA. .; Division of Developmental Neuroscience, Department of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA. .; Sackler Institute for Developmental Psychobiology, Columbia University Vagelos College of Physicians and Surgeons and the New York State Psychiatric Institute, New York, NY, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 24; Vol. 11 (1), pp. 22852. Date of Electronic Publication: 2021 Nov 24.
Typ publikacji:
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Antidepressive Agents, Second-Generation/*toxicity
Antidepressive Agents, Tricyclic/*pharmacology
Avoidance Learning/*drug effects
Behavior, Animal/*drug effects
Brain/*drug effects
Fluoxetine/*toxicity
Selective Serotonin Reuptake Inhibitors/*toxicity
Thiazepines/*pharmacology
Animals ; Animals, Newborn ; Brain/growth & development ; Feeding Behavior/drug effects ; Mice, 129 Strain ; Mice, Inbred C57BL ; Open Field Test/drug effects ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
CXCR5 down-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy: potential role of microglial autophagy and the p38MAPK/NF-κB/STAT3 signaling pathway.
Autorzy:
Shen Y; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Zhang Y; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Du J; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Jiang B; Institute of Pain Medicine and Special Environmental Medicine, Nantong University, Nantong, 226019, Jiangsu, China.
Shan T; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Li H; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Bao H; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China.
Si Y; Department of Anesthesiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006, Jiangsu, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2021 Oct 28; Vol. 18 (1), pp. 246. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji:
Journal Article
MeSH Terms:
Cognitive Dysfunction/*metabolism
NF-kappa B/*metabolism
Receptors, CXCR5/*deficiency
STAT3 Transcription Factor/*metabolism
Sepsis-Associated Encephalopathy/*metabolism
p38 Mitogen-Activated Protein Kinases/*metabolism
Animals ; Autophagy/physiology ; Cognitive Dysfunction/genetics ; Cognitive Dysfunction/prevention & control ; Down-Regulation/physiology ; Male ; Maze Learning/physiology ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Microglia/metabolism ; NF-kappa B/genetics ; Receptors, CXCR5/genetics ; STAT3 Transcription Factor/genetics ; Sepsis-Associated Encephalopathy/genetics ; Signal Transduction/physiology ; p38 Mitogen-Activated Protein Kinases/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury.
Autorzy:
Tan SW; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Zhao Y; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Li P; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Ning YL; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Huang ZZ; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Yang N; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China.
Liu D; Medical Center of Trauma and War Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing, China.
Zhou YG; State Key Laboratory of Trauma, Burns and Combined Injury, Department of Occupational Disease, Daping Hospital, Army Medical University, Chongqing, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2021 Oct 19; Vol. 18 (1), pp. 241. Date of Electronic Publication: 2021 Oct 19.
Typ publikacji:
Journal Article
MeSH Terms:
Brain Injuries, Traumatic/*metabolism
Cognitive Dysfunction/*metabolism
HMGB1 Protein/*metabolism
NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism
Animals ; Brain Injuries, Traumatic/pathology ; Cells, Cultured ; Cerebral Cortex/metabolism ; Cerebral Cortex/pathology ; Coculture Techniques ; Cognitive Dysfunction/pathology ; Excitatory Postsynaptic Potentials/physiology ; Hippocampus/metabolism ; Hippocampus/pathology ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Organ Culture Techniques
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Perineuronal Nets in the Prefrontal Cortex of a Schizophrenia Mouse Model: Assessment of Neuroanatomical, Electrophysiological, and Behavioral Contributions.
Autorzy:
Sultana R; Department of Comparative Biomedical Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
Brooks CB; Department of Comparative Biomedical Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
Shrestha A; Department of Comparative Biomedical Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
Ogundele OM; Department of Comparative Biomedical Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
Lee CC; Department of Comparative Biomedical Sciences, LSU School of Veterinary Medicine, Baton Rouge, LA 70803, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji:
Journal Article
MeSH Terms:
Behavior, Animal/*physiology
Nerve Net/*pathology
Prefrontal Cortex/*pathology
Schizophrenia/*pathology
Animals ; Disease Models, Animal ; Electrophysiological Phenomena ; Female ; Interneurons/pathology ; Interneurons/physiology ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Nerve Net/anatomy & histology ; Nerve Net/physiopathology ; Neurons/pathology ; Neurons/physiology ; Prefrontal Cortex/anatomy & histology ; Prefrontal Cortex/physiopathology ; Schizophrenia/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
The Absence of Extracellular Cold-Inducible RNA-Binding Protein (eCIRP) Promotes Pro-Angiogenic Microenvironmental Conditions and Angiogenesis in Muscle Tissue Ischemia.
Autorzy:
Kübler M; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Ludwig- Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.
Beck S; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Ludwig- Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.
Peffenköver LL; Department of Biochemistry, Faculty of Medicine, Justus Liebig University, 35392 Giessen, Germany.
Götz P; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Ludwig- Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.
Ishikawa-Ankerhold H; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Department of Internal Medicine I, Faculty of Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
Preissner KT; Department of Biochemistry, Faculty of Medicine, Justus Liebig University, 35392 Giessen, Germany.
Fischer S; Department of Biochemistry, Faculty of Medicine, Justus Liebig University, 35392 Giessen, Germany.
Lasch M; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Ludwig- Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.
Deindl E; Walter-Brendel-Centre of Experimental Medicine, University Hospital, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.; Biomedical Center, Institute of Cardiovascular Physiology and Pathophysiology, Ludwig- Maximilians-Universität München, 82152 Planegg-Martinsried, Germany.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 31; Vol. 22 (17). Date of Electronic Publication: 2021 Aug 31.
Typ publikacji:
Journal Article
MeSH Terms:
Ischemia/*pathology
Neovascularization, Physiologic/*physiology
RNA-Binding Proteins/*metabolism
Animals ; Disease Models, Animal ; Endothelial Cells/metabolism ; Extracellular Traps/metabolism ; Inflammation/pathology ; Ischemia/metabolism ; Leukocyte Count ; Leukocytes/metabolism ; Macrophage Activation ; Macrophages/metabolism ; Male ; Mice ; Mice, 129 Strain ; Muscles/metabolism ; Neutrophils/metabolism ; RNA-Binding Proteins/physiology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Loss of the ciliary protein Chibby1 in mice leads to exocrine pancreatic degeneration and pancreatitis.
Autorzy:
Cyge B; Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY, 11794, USA.
Voronina V; Department of Pharmacology, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine and Howard Hughes Medical Institute, Seattle, WA, 98195, USA.
Hoque M; Graduate Program in Molecular and Cellular Biology, Stony Brook University, Stony Brook, NY, 11794, USA.
Kim EN; Graduate Program in Molecular and Cellular Biology, Stony Brook University, Stony Brook, NY, 11794, USA.
Hall J; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, 32224, USA.
Bailey-Lundberg JM; Department of Anesthesiology, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, TX, 77030, USA.
Pazour GJ; Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, 01605, USA.
Crawford HC; Department of Cancer Biology, Mayo Clinic, Jacksonville, FL, 32224, USA.; Henry Ford Health System, Detroit, MI, 48202, USA.
Moon RT; Department of Pharmacology, Institute for Stem Cell and Regenerative Medicine, University of Washington School of Medicine and Howard Hughes Medical Institute, Seattle, WA, 98195, USA.
Li FQ; Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY, 11794, USA.; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 11974, USA.
Takemaru KI; Graduate Program in Molecular and Cellular Pharmacology, Stony Brook University, Stony Brook, NY, 11794, USA. .; Graduate Program in Molecular and Cellular Biology, Stony Brook University, Stony Brook, NY, 11794, USA. .; Department of Pharmacological Sciences, Stony Brook University, Stony Brook, NY, 11974, USA. .; Department of Pharmacological Sciences, Stony Brook University, BST 7-182, 101 Nicolls Rd., Stony Brook, NY, 11794-8651, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 26; Vol. 11 (1), pp. 17220. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Carrier Proteins/*genetics
Cilia/*metabolism
Pancreas/*metabolism
Pancreas, Exocrine/*metabolism
Pancreatitis/*genetics
Acinar Cells/metabolism ; Animals ; Atrophy ; Carrier Proteins/metabolism ; Ciliopathies/genetics ; Ciliopathies/metabolism ; Exocytosis/genetics ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Microscopy, Electron, Transmission ; Pancreas/pathology ; Pancreas/ultrastructure ; Pancreas, Exocrine/pathology ; Pancreatitis/metabolism ; Secretory Vesicles/metabolism ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Downregulation of CD40L-CD40 attenuates seizure susceptibility and severity of seizures.
Autorzy:
Pototskiy E; Department of Pathology and Anatomy, Eastern Virginia Medical School, 700 W. Olney Road, Lewis Hall, Office 2174, Norfolk, VA, 23507, USA.
Vinokuroff K; Eastern Virginia Medical School, Norfolk, VA, USA.
Ojeda A; Department of Pathology and Anatomy, Eastern Virginia Medical School, 700 W. Olney Road, Lewis Hall, Office 2174, Norfolk, VA, 23507, USA.
Major CK; Eastern Virginia Medical School, Norfolk, VA, USA.
Sharma D; Eastern Virginia Medical School, Norfolk, VA, USA.
Anderson T; Eastern Virginia Medical School, Norfolk, VA, USA.
Howard K; Eastern Virginia Medical School, Norfolk, VA, USA.
Borenstein R; Department of Microbiology and Molecular Cell Biology, Eastern Virginia Medical School, Norfolk, VA, 23507, USA.
Musto AE; Department of Pathology and Anatomy, Eastern Virginia Medical School, 700 W. Olney Road, Lewis Hall, Office 2174, Norfolk, VA, 23507, USA. .; Department of Neurology, Eastern Virginia Medical School, 700 W. Olney Road, Lewis Hall, Office 2174, Norfolk, VA, 23507, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 26; Vol. 11 (1), pp. 17262. Date of Electronic Publication: 2021 Aug 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Disease Models, Animal*
Down-Regulation*
CD40 Antigens/*metabolism
CD40 Ligand/*metabolism
Epilepsy, Temporal Lobe/*metabolism
Seizures/*metabolism
Animals ; CD40 Antigens/genetics ; Epilepsy, Temporal Lobe/chemically induced ; Epilepsy, Temporal Lobe/genetics ; Genetic Predisposition to Disease/genetics ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Male ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Neurons/metabolism ; Pentylenetetrazole ; Seizures/chemically induced ; Seizures/genetics ; Severity of Illness Index ; Status Epilepticus/metabolism ; Mice
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Derivation of Mouse Parthenogenetic Advanced Stem Cells.
Autorzy:
Wei M; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Zhang J; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Liu J; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Zhao C; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Cao S; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Yan X; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Wu B; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
Bao S; State Key Laboratory of Reproductive Regulation and Breeding of Grassland Livestock, Inner Mongolia University, Hohhot 010020, China.; Institute for Animal Genetic Research of Mongolia Plateau, College of Life Sciences, Inner Mongolia University, Hohhot 010020, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 20; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 20.
Typ publikacji:
Journal Article
MeSH Terms:
Embryonic Stem Cells/*cytology
Embryonic Stem Cells/*metabolism
Parthenogenesis/*physiology
Activins/metabolism ; Animals ; Blastocyst/metabolism ; Bone Morphogenetic Protein 4/pharmacology ; Cell Culture Techniques/methods ; Cell Differentiation/drug effects ; DNA Methylation/drug effects ; Embryo Culture Techniques/methods ; Female ; Fibroblast Growth Factors/pharmacology ; Germ Layers/metabolism ; Germ Layers/physiology ; Leukemia Inhibitory Factor/pharmacology ; Mice ; Mice, 129 Strain ; Mice, Inbred ICR ; Mouse Embryonic Stem Cells/cytology ; Parthenogenesis/genetics ; Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/pathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Evaluation of Class IIa Histone Deacetylases Expression and In Vivo Epigenetic Imaging in a Transgenic Mouse Model of Alzheimer's Disease.
Autorzy:
Chen YA; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Molecular and Genetic Imaging Core/Taiwan Mouse Clinic, National Comprehensive Mouse Phenotyping and Drug Testing Center, Taipei 112, Taiwan.; Department of Nuclear Medicine, Cheng Hsin Hospital, Taipei 112, Taiwan.
Lu CH; Molecular and Genetic Imaging Core/Taiwan Mouse Clinic, National Comprehensive Mouse Phenotyping and Drug Testing Center, Taipei 112, Taiwan.; Industrial Ph.D Program of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Ke CC; Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung 807, Taiwan.; Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung 807, Taiwan.; Drug Development and Value Creation Research Center, Kaohsiung Medical University, Kaohsiung 807, Taiwan.
Chiu SJ; Molecular and Genetic Imaging Core/Taiwan Mouse Clinic, National Comprehensive Mouse Phenotyping and Drug Testing Center, Taipei 112, Taiwan.
Chang CW; National PET and Cyclotron Center (NPCC), Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.
Yang BH; National PET and Cyclotron Center (NPCC), Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei 112, Taiwan.; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Gelovani JG; Office of the Provost, United Arab Emirates University, Al Ain P.O. Box 1551, United Arab Emirates.
Liu RS; Institute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Molecular and Genetic Imaging Core/Taiwan Mouse Clinic, National Comprehensive Mouse Phenotyping and Drug Testing Center, Taipei 112, Taiwan.; Department of Nuclear Medicine, Cheng Hsin Hospital, Taipei 112, Taiwan.; Industrial Ph.D Program of Biomedical Science and Engineering, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.; Department of Biomedical Imaging and Radiological Sciences, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 11; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease/*diagnostic imaging
Histone Deacetylase Inhibitors/*pharmacokinetics
Histone Deacetylases/*metabolism
Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Alzheimer Disease/pathology ; Anilides/chemistry ; Anilides/pharmacokinetics ; Animals ; Brain/diagnostic imaging ; Brain/metabolism ; Disease Models, Animal ; Epigenesis, Genetic/drug effects ; Epigenesis, Genetic/physiology ; Fluorine Radioisotopes/chemistry ; Fluorine Radioisotopes/pharmacokinetics ; Fluoroacetates/chemistry ; Fluoroacetates/pharmacokinetics ; Gene Expression Regulation, Enzymologic/drug effects ; Histone Deacetylase Inhibitors/chemistry ; Histone Deacetylases/classification ; Histone Deacetylases/genetics ; Humans ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Transgenic ; Neuroimaging/methods ; Positron-Emission Tomography/methods ; Tumor Cells, Cultured
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Epidermal PPARγ Is a Key Homeostatic Regulator of Cutaneous Inflammation and Barrier Function in Mouse Skin.
Autorzy:
Konger RL; Department of Pathology & Laboratory Medicine, Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; The Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Derr-Yellin E; Department of Pathology & Laboratory Medicine, Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.; Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Zimmers TA; The Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Katona T; Department of Pathology & Laboratory Medicine, Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.
Xuei X; Department of Surgery, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Liu Y; The Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Medical and Molecular Genetics, Indiana University, Indianapolis, IN 46202, USA.
Zhou HM; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
Simpson ER Jr; Center for Medical Genomics, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of BioHealth Informatics, Indiana University-Purdue University Indianapolis, Indianapolis, IN 46202, USA.
Turner MJ; Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.; Department of Dermatology, Richard L. Roudebush Veterans Affairs Medical Center, Indianapolis, IN 46202, USA.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2021 Aug 11; Vol. 22 (16). Date of Electronic Publication: 2021 Aug 11.
Typ publikacji:
Journal Article
MeSH Terms:
Dermatitis/*genetics
Epidermis/*metabolism
PPAR gamma/*physiology
Skin Physiological Phenomena/*genetics
Animals ; Cells, Cultured ; Dermatitis/metabolism ; Dermatitis/pathology ; Dermatitis/physiopathology ; Epidermis/physiology ; Homeostasis/genetics ; Inflammation/genetics ; Inflammation/metabolism ; Inflammation/pathology ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Organ Specificity/genetics ; PPAR gamma/genetics ; PPAR gamma/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Loss of dysferlin or myoferlin results in differential defects in excitation-contraction coupling in mouse skeletal muscle.
Autorzy:
Barefield DY; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA. .; Department of Cell and Molecular Physiology, Loyola University Chicago, 2160 S. 1st Ave, Maywood, IL, 60153, USA. .
Sell JJ; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA.
Tahtah I; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA.
Kearns SD; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA.
McNally EM; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA.
Demonbreun AR; Center for Genetic Medicine, Feinberg School of Medicine, Northwestern University, 303 E Superior Lurie 5-500, Chicago, IL, 60611, USA. .; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA. .; Center for Genetic Medicine, Northwestern University, 303 E Superior Lurie 5-512, Chicago, IL, 60611, USA. .
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Źródło:
Scientific reports [Sci Rep] 2021 Aug 05; Vol. 11 (1), pp. 15865. Date of Electronic Publication: 2021 Aug 05.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:
Dysferlin/*metabolism
Excitation Contraction Coupling/*physiology
Membrane Proteins/*metabolism
Muscle Proteins/*metabolism
Animals ; Calcium-Binding Proteins/metabolism ; Cell Membrane/metabolism ; Dysferlin/genetics ; Female ; Male ; Membrane Fusion/physiology ; Membrane Proteins/genetics ; Mice ; Mice, 129 Strain ; Muscle Contraction/physiology ; Muscle Proteins/genetics ; Muscle, Skeletal/metabolism ; Muscle, Skeletal/physiology ; Muscular Dystrophies/physiopathology
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aggravation of hepatic ischemia‑reperfusion injury with increased inflammatory cell infiltration is associated with the TGF‑β/Smad3 signaling pathway.
Autorzy:
Li H; Department of Immunology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Shen X; Key Laboratory of Endoscopic Technology Research, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, P.R. China.
Tong Y; Key Laboratory of Endoscopic Technology Research, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, P.R. China.
Ji T; Key Laboratory of Endoscopic Technology Research, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310016, P.R. China.
Feng Y; Research Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Tang Y; Research Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Mai R; Research Department, Affiliated Tumor Hospital of Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Ye J; Department of Immunology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Que T; Department of Immunology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
Luo X; Department of Immunology, School of Basic Medical Sciences, Guangxi Medical University, Nanning, Guangxi 530021, P.R. China.
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Źródło:
Molecular medicine reports [Mol Med Rep] 2021 Aug; Vol. 24 (2). Date of Electronic Publication: 2021 Jun 16.
Typ publikacji:
Journal Article
MeSH Terms:
Apoptosis*
Signal Transduction*
Inflammation/*pathology
Reperfusion Injury/*metabolism
Smad3 Protein/*metabolism
Transforming Growth Factor beta1/*metabolism
Alanine Transaminase/blood ; Animals ; Liver/metabolism ; Liver Cirrhosis/metabolism ; Mice ; Mice, 129 Strain ; Mice, Knockout ; Smad3 Protein/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Functional MRI for characterization of renal perfusion impairment and edema formation due to acute kidney injury in different mouse strains.
Autorzy:
Tewes S; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Gueler F; Nephrology, Hannover Medical School, Hannover, Germany.
Chen R; Nephrology, Hannover Medical School, Hannover, Germany.
Gutberlet M; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Jang MS; Nephrology, Hannover Medical School, Hannover, Germany.
Meier M; Laboratory Animal Science, Hannover Medical School, Hannover, Germany.
Mengel M; Department of Laboratory Medicine & Pathology, University of Alberta, Edmonton, Canada.
Hartung D; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Wacker F; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
Rong S; Nephrology, Hannover Medical School, Hannover, Germany.; The Transplantation Center of the affiliated hospital, Zunyi Medical College, Zunyi, China.
Hueper K; Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany.
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Źródło:
PloS one [PLoS One] 2017 Mar 20; Vol. 12 (3), pp. e0173248. Date of Electronic Publication: 2017 Mar 20 (Print Publication: 2017).
Typ publikacji:
Comparative Study; Journal Article
MeSH Terms:
Disease Models, Animal*
Magnetic Resonance Imaging*
Mice, 129 Strain*
Mice, Inbred C57BL*
Acute Kidney Injury/*diagnostic imaging
Kidney/*diagnostic imaging
Acute Kidney Injury/pathology ; Acute Kidney Injury/physiopathology ; Animals ; Disease Progression ; Edema/diagnostic imaging ; Edema/pathology ; Edema/physiopathology ; Fibrosis/diagnostic imaging ; Fibrosis/pathology ; Fibrosis/physiopathology ; Immunohistochemistry ; Kidney/pathology ; Kidney/physiopathology ; Macrophages/pathology ; Macrophages/physiology ; Male ; Organ Size ; Reperfusion Injury ; Severity of Illness Index ; Species Specificity ; Time Factors
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Characterization of the blood-brain barrier in genetically diverse laboratory mouse strains.
Autorzy:
Schaffenrath J; Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zürich, Zürich University, Zürich, Switzerland.; Neuroscience Center Zürich, University of Zürich and ETH Zürich, Zürich, Switzerland.
Huang SF; Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zürich, Zürich University, Zürich, Switzerland.; Neuroscience Center Zürich, University of Zürich and ETH Zürich, Zürich, Switzerland.
Wyss T; Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Oncology, University Lausanne, Lausanne, Switzerland.
Delorenzi M; Bioinformatics Core Facility, Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Department of Oncology, University Lausanne, Lausanne, Switzerland.
Keller A; Department of Neurosurgery, Clinical Neuroscience Center, University Hospital Zürich, Zürich University, Zürich, Switzerland. .; Neuroscience Center Zürich, University of Zürich and ETH Zürich, Zürich, Switzerland. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2021 Jul 28; Vol. 18 (1), pp. 34. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji:
Journal Article
MeSH Terms:
Blood-Brain Barrier/*metabolism
Capillary Permeability/*physiology
Cerebral Cortex/*metabolism
Genetic Variation/*physiology
Hippocampus/*metabolism
Animals ; Blood-Brain Barrier/cytology ; Blood-Brain Barrier/drug effects ; Cerebral Cortex/cytology ; Cerebral Cortex/drug effects ; Female ; Fluorescein/administration & dosage ; Fluorescein/metabolism ; Fluorescent Dyes/administration & dosage ; Fluorescent Dyes/metabolism ; Genetic Variation/drug effects ; Hippocampus/cytology ; Hippocampus/drug effects ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Inbred DBA ; Mice, Inbred NOD ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknieSzczegóły
Tytuł:
Group 2 innate lymphoid cells are numerically and functionally deficient in the triple transgenic mouse model of Alzheimer's disease.
Autorzy:
Fung ITH; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Zhang Y; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Shin DS; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, 12208, USA.
Sankar P; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Sun X; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
D'Souza SS; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA.
Song R; Biochemistry & Immunology Core Facility at Wadsworth Center, New York State Department of Health, Albany, NY, USA.
Kuentzel ML; Center for Functional Genomics, University at Albany-SUNY, Rensselaer, NY, 12144, USA.
Chittur SV; Center for Functional Genomics, University at Albany-SUNY, Rensselaer, NY, 12144, USA.
Zuloaga KL; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, 12208, USA.
Yang Q; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY, 12208, USA. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2021 Jul 06; Vol. 18 (1), pp. 152. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease/*genetics
Alzheimer Disease/*immunology
Immunity, Innate/*genetics
Immunity, Innate/*immunology
Lymphocytes/*immunology
Animals ; Cells, Cultured ; Female ; Male ; Mice ; Mice, 129 Strain ; Mice, Transgenic
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Factors influencing the acute pentylenetetrazole-induced seizure paradigm and a literature review.
Autorzy:
Yuskaitis CJ; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Division of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Rossitto LA; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Groff KJ; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Dhamne SC; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Zhang B; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Biostatistics and Research Design Center, Institutional Centers for Clinical and Translational Research, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Lalani LK; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, Massachusetts, 02115, USA.
Singh AK; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, Massachusetts, 02115, USA.
Rotenberg A; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Division of Epilepsy and Clinical Neurophysiology and Epilepsy Genetics Program, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Neuromodulation Program, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.
Sahin M; F.M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, 02115, USA.; Rosamund Stone Zander Translational Neuroscience Center, Boston Children's Hospital, Boston, Massachusetts, 02115, USA.
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Źródło:
Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2021 Jul; Vol. 8 (7), pp. 1388-1397. Date of Electronic Publication: 2021 Jun 08.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review
MeSH Terms:
Social Isolation*
Convulsants/*toxicity
Pentylenetetrazole/*toxicity
Seizures/*chemically induced
Seizures/*physiopathology
Age Factors ; Animals ; Electroencephalography/methods ; Female ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Inbred CBA ; Seizures/genetics ; Sex Factors ; Species Specificity
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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