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Wyszukujesz frazę ""Mice, Inbred C57BL"" wg kryterium: Temat


Tytuł:
Metabolic differences and differentially expressed genes between C57BL/6J and C57BL/6N mice substrains.
Autorzy:
Nemoto S; Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.
Kubota T; Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.; Division of Diabetes and Metabolism, The Institute of Medical Science, Asahi Life Foundation, Tokyo, Japan.; Department of Clinical Nutrition, National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN), Tokyo, Japan.; Division of Cardiovascular Medicine, Toho University Ohashi Medical Center, Tokyo, Japan.; Department of Diabetes and Metabolic Diseases, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Ohno H; Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Kanagawa, Japan.; Laboratory for Immune Regulation, Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan.; Immunobiology Laboratory, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan.
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Źródło:
PloS one [PLoS One] 2022 Dec 22; Vol. 17 (12), pp. e0271651. Date of Electronic Publication: 2022 Dec 22 (Print Publication: 2022).
Typ publikacji:
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mice, Inbred C57BL*/metabolism
Metabolism*/genetics
Animals ; Mice ; Genotype ; Mice, Transgenic ; Mutation ; NADP Transhydrogenases/genetics
Czasopismo naukowe
Tytuł:
The sex-specific metabolic signature of C57BL/6NRj mice during aging.
Autorzy:
Bresilla D; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/VI, 8010, Graz, Austria.
Habisch H; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/VI, 8010, Graz, Austria.
Pritišanac I; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/VI, 8010, Graz, Austria.
Zarse K; Laboratory of Energy Metabolism, Department of Health Sciences and Technology, Institute of Translational Medicine, ETH Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland.
Parichatikanond W; Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Bangkok, 10400, Thailand.; Faculty of Pharmacy, Center of Biopharmaceutical Science for Healthy Ageing (BSHA), Mahidol University, Bangkok, 10400, Thailand.
Ristow M; Laboratory of Energy Metabolism, Department of Health Sciences and Technology, Institute of Translational Medicine, ETH Zurich, Schorenstrasse 16, 8603, Schwerzenbach, Switzerland.
Madl T; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/VI, 8010, Graz, Austria. .; BioTechMed-Graz, Graz, Austria. .
Madreiter-Sokolowski CT; Molecular Biology and Biochemistry, Gottfried Schatz Research Center, Medical University of Graz, Neue Stiftingtalstraße 6/VI, 8010, Graz, Austria. .; BioTechMed-Graz, Graz, Austria. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 06; Vol. 12 (1), pp. 21050. Date of Electronic Publication: 2022 Dec 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mice, Inbred C57BL*/metabolism
Aging*
Animals ; Female ; Male ; Mice
Czasopismo naukowe
Tytuł:
PAK4 inhibition improves PD1 blockade immunotherapy in prostate cancer by increasing immune infiltration.
Autorzy:
Su S; Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
You S; Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
Wang Y; Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
Tamukong P; Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
Quist MJ; Cedars-Sinai Medical Center, Los Angeles, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
Grasso CS; Cedars-Sinai Medical Center, Los Angeles, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
Kim HL; Department of Surgery, Cedars-Sinai Medical Center, 8700 Beverly Blvd, Los Angeles, CA, 90048, USA. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2023 Feb 28; Vol. 555, pp. 216034. Date of Electronic Publication: 2022 Dec 10.
Typ publikacji:
Journal Article
MeSH Terms:
p21-Activated Kinases*/genetics
p21-Activated Kinases*/metabolism
Prostatic Neoplasms*/drug therapy
Prostatic Neoplasms*/genetics
Animals ; Humans ; Male ; Mice ; CD8-Positive T-Lymphocytes ; Cell Line, Tumor ; Immunotherapy ; Mice, Inbred C57BL ; Tumor Microenvironment
Czasopismo naukowe
Tytuł:
Ergosterol fraction from Agaricus bisporus modulates adipogenesis and skeletal glucose uptake in high fat diet induced obese C57BL/6 mice.
Autorzy:
Das M; Department of Biochemistry, CSIR-Central Food Technological Research Institute, Mysore 570 020, Karnataka, India; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad 201002, India.
Gurusiddaiah SK; Department of Biochemistry, CSIR-Central Food Technological Research Institute, Mysore 570 020, Karnataka, India. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Feb 15; Vol. 315, pp. 121337. Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Adipogenesis*
Anti-Obesity Agents*/pharmacology
Male ; Mice ; Animals ; Diet, High-Fat/adverse effects ; Mice, Inbred C57BL ; Obesity/drug therapy ; Obesity/etiology ; Obesity/metabolism ; Cholesterol ; Glucose/pharmacology ; 3T3-L1 Cells ; PPAR gamma/metabolism ; Mice, Obese
SCR Organism:
Agaricus bisporus
Czasopismo naukowe
Tytuł:
Phenolics from noni (Morinda citrifolia L.) fruit alleviate obesity in high fat diet-fed mice via modulating the gut microbiota and mitigating intestinal damage.
Autorzy:
Wang R; School of Food Science and Engineering, Hainan University, Haikou 570228, China.
Wang L; School of Food Science and Engineering, Hainan University, Haikou 570228, China; Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Haikou 570228, China; Key Laboratory of Tropical Agricultural Products Processing Technology of Haikou, Haikou 570228, China.
Wang S; School of Food Science and Engineering, Hainan University, Haikou 570228, China.
Wang J; School of Food Science and Engineering, Hainan University, Haikou 570228, China.
Su C; School of Food Science and Engineering, Hainan University, Haikou 570228, China.
Zhang L; School of Food Science and Engineering, Hainan University, Haikou 570228, China; Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Haikou 570228, China; Key Laboratory of Tropical Agricultural Products Processing Technology of Haikou, Haikou 570228, China.
Li C; School of Food Science and Engineering, Hainan University, Haikou 570228, China; Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Haikou 570228, China; Key Laboratory of Tropical Agricultural Products Processing Technology of Haikou, Haikou 570228, China. Electronic address: .
Liu S; Key Laboratory of Food Nutrition and Functional Food of Hainan Province, Haikou 570228, China; Key Laboratory of Tropical Agricultural Products Processing Technology of Haikou, Haikou 570228, China; School of Science, Hainan University, Haikou 570228, China. Electronic address: .
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Źródło:
Food chemistry [Food Chem] 2023 Feb 15; Vol. 402, pp. 134232. Date of Electronic Publication: 2022 Sep 15.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
Morinda*/metabolism
Mice ; Animals ; Diet, High-Fat/adverse effects ; Lipopolysaccharides/pharmacology ; Fruit/metabolism ; Occludin/metabolism ; Toll-Like Receptor 4 ; NF-kappa B/genetics ; Claudin-1/pharmacology ; Mice, Inbred C57BL ; Obesity/drug therapy ; Obesity/genetics ; Obesity/metabolism ; Fatty Acids, Volatile/metabolism ; Phenols/pharmacology ; Inflammation/drug therapy ; Inflammation/genetics ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Peroxisome proliferator-activated receptors-alpha and gamma synergism modulate the gut-adipose tissue axis and mitigate obesity.
Autorzy:
Miranda CS; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Silva-Veiga FM; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Fernandes-da-Silva A; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Guimarães Pereira VR; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Martins BC; Laboratory for Studies of Interactions Between Nutrition and Genetics (LEING), Institute of Nutrition, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Daleprane JB; Laboratory for Studies of Interactions Between Nutrition and Genetics (LEING), Institute of Nutrition, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Martins FF; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil.
Souza-Mello V; Laboratory of Morphometry, Metabolism and Cardiovascular Diseases, Biomedical Center, Institute of Biology, Rio de Janeiro State University, Rio de Janeiro, Brazil. Electronic address: .
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Źródło:
Molecular and cellular endocrinology [Mol Cell Endocrinol] 2023 Feb 15; Vol. 562, pp. 111839. Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article
MeSH Terms:
Endotoxemia*
PPAR alpha*/metabolism
Animals ; Male ; Mice ; Adipose Tissue, Brown/metabolism ; Diet, High-Fat ; Lipids ; Mice, Inbred C57BL ; Obesity/metabolism ; PPAR gamma/metabolism
Czasopismo naukowe
Tytuł:
Salecan confers anti-inflammatory effects in liver injury via regulating gut microbiota and its metabolites.
Autorzy:
Liu Y; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China.
Li P; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China.
Pan W; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China.
Zhao J; Sichuan Synlight Biotech Ltd., 88 Keyuan South Road, Chengdu 610000, Sichuan, China.
Olnood CG; Sichuan Synlight Biotech Ltd., 88 Keyuan South Road, Chengdu 610000, Sichuan, China.
Liu Y; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China.
Xu YJ; State Key Laboratory of Food Science and Technology, School of Food Science and Technology, National Engineering Research Center for Functional Food, National Engineering Research Center of Cereal Fermentation and Food Biomanufacturing, Collaborative Innovation Center of Food Safety and Quality Control in Jiangsu Province, Jiangnan University, 1800 Lihu Road, Wuxi 214122, Jiangsu, China. Electronic address: .
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Źródło:
Carbohydrate polymers [Carbohydr Polym] 2023 Feb 15; Vol. 302, pp. 120418. Date of Electronic Publication: 2022 Nov 28.
Typ publikacji:
Journal Article
MeSH Terms:
Gastrointestinal Microbiome*
beta-Glucans*/pharmacology
Animals ; Mice ; Liver ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/metabolism ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Starch from Pueraria lobata and the amylose fraction alleviates dextran sodium sulfate induced colitis in mice.
Autorzy:
Yang Y; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China.
Li M; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; South Sichuan Institute of Translational Medicine, 646000 Luzhou, Sichuan, China.
Liu Q; The First People's Hospital of Neijiang, 641000 Neijiang, Sichuan, China.
Zhao Q; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China.
Zeng J; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China.
Wang Q; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China.
Zhao Y; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; South Sichuan Institute of Translational Medicine, 646000 Luzhou, Sichuan, China.
Du F; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; South Sichuan Institute of Translational Medicine, 646000 Luzhou, Sichuan, China.
Chen Y; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; South Sichuan Institute of Translational Medicine, 646000 Luzhou, Sichuan, China.
Shen J; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; South Sichuan Institute of Translational Medicine, 646000 Luzhou, Sichuan, China.
Luo H; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China.
Wang S; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 999078, Macao.
Li W; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Chen M; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Li X; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Wang F; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Sun Y; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Gu L; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China.
Xiao Z; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Department of Oncology, Affiliated Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China. Electronic address: .
Du Y; Medical Cosmetology Center, Affiliated Hospital of Traditional Chinese Medicine, Southwest Medical University, 646000 Luzhou, Sichuan, China. Electronic address: .
Wu X; Laboratory of Molecular Pharmacology, Department of Pharmacology, School of Pharmacy, Southwest Medical University, 646000 Luzhou, Sichuan, China; Cell Therapy & Cell Drugs of Luzhou Key Laboratory, 646000 Luzhou, Sichuan, China; State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, 999078, Macao. Electronic address: .
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Źródło:
Carbohydrate polymers [Carbohydr Polym] 2023 Feb 15; Vol. 302, pp. 120329. Date of Electronic Publication: 2022 Nov 11.
Typ publikacji:
Journal Article
MeSH Terms:
Pueraria*
Colitis*/chemically induced
Colitis*/drug therapy
Mice ; Animals ; Amylose ; Dextrans ; Starch ; Colon ; Dextran Sulfate/toxicity ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
ASGR1 promotes liver injury in sepsis by modulating monocyte-to-macrophage differentiation via NF-κB/ATF5 pathway.
Autorzy:
Shi R; Xiangya School of Pharmaceutical Sciences, Central South University, Changsha, China; Center for Vascular Disease and Translational Medicine, The Third Xiangya Hospital of Central South University, Changsha, China.
Wang J; Health Management Center, the Third Xiangya Hospital, Central South University, Changsha, China. Electronic address: .
Zhang Z; Center for Vascular Disease and Translational Medicine, The Third Xiangya Hospital of Central South University, Changsha, China.
Leng Y; The Affiliated Changsha Central Hospital, Research Center for Phase I Clinical Trials, Hengyang Medical School, University of South China, Changsha, Hunan, China.
Chen AF; Center for Vascular Disease and Translational Medicine, The Third Xiangya Hospital of Central South University, Changsha, China; Institute for Developmental and Regenerative Cardiovascular Medicine, Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Feb 15; Vol. 315, pp. 121339. Date of Electronic Publication: 2023 Jan 05.
Typ publikacji:
Journal Article
MeSH Terms:
Chemical and Drug Induced Liver Injury, Chronic*/metabolism
Sepsis*/complications
Sepsis*/metabolism
Mice ; Animals ; Monocytes/metabolism ; NF-kappa B/metabolism ; Leukocytes, Mononuclear/metabolism ; Macrophages/metabolism ; Cell Differentiation ; Mice, Inbred C57BL ; Activating Transcription Factors/metabolism
Czasopismo naukowe
Tytuł:
Formononetin ameliorates ferroptosis-associated fibrosis in renal tubular epithelial cells and in mice with chronic kidney disease by suppressing the Smad3/ATF3/SLC7A11 signaling.
Autorzy:
Zhu B; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China; Southwest Medical University, 646000 Luzhou, Sichuan, China.
Ni Y; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.
Gong Y; Southwest Medical University, 646000 Luzhou, Sichuan, China; Department of Nephrology, The Affiliated Traditional Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.
Kang X; Southwest Medical University, 646000 Luzhou, Sichuan, China.
Guo H; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.
Liu X; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China.
Li J; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China. Electronic address: .
Wang L; Research Center of Integrated Traditional Chinese and Western Medicine, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, 646000 Luzhou, Sichuan, China; Institute of Integrated Chinese and Western Medicine, Southwest Medical University, 646000 Luzhou, Sichuan, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Feb 15; Vol. 315, pp. 121331. Date of Electronic Publication: 2022 Dec 29.
Typ publikacji:
Journal Article
MeSH Terms:
Ferroptosis*
Renal Insufficiency, Chronic*/metabolism
Ureteral Obstruction*/complications
Ureteral Obstruction*/drug therapy
Ureteral Obstruction*/metabolism
Mice ; Animals ; Kidney/metabolism ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; Mice, Inbred C57BL ; Fibrosis ; Epithelial Cells/metabolism
Czasopismo naukowe
Tytuł:
Toll-like receptor 9 signaling after myocardial infarction: Role of p66ShcA adaptor protein.
Autorzy:
Baysa A; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway.
Maghazachi AA; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway.
Sand KL; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway.
Campesan M; Department of Biomedical Sciences, University of Padua, Padua, Italy.
Zaglia T; Venetian Institute of Molecular Medicine, Padova, Italy.
Mongillo M; Department of Biomedical Sciences, University of Padua, Padua, Italy; CNR Institute of Neuroscience, University of Padua, Padua, Italy; Venetian Institute of Molecular Medicine, Padova, Italy.
Giorgio M; Department of Experimental Oncology, European Institute of Oncology, Milan, Italy.
Di Lisa F; Department of Biomedical Sciences, University of Padua, Padua, Italy; CNR Institute of Neuroscience, University of Padua, Padua, Italy.
Gullestad L; Department of Cardiology, Oslo University Hospital, Oslo, Norway; KG Jebsen Center for Cardiac Research, University of Oslo, Norway.
Mariero LH; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway.
Vaage J; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway; Department of Research and Development, Division of Critical Care and Emergencies, Oslo University Hospital, Oslo, Norway; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.
Valen G; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway.
Stensløkken KO; Department of Molecular Medicine, Institute of Basic Medical Science University of Oslo, Norway. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Feb 12; Vol. 644, pp. 70-78. Date of Electronic Publication: 2022 Dec 30.
Typ publikacji:
Journal Article
MeSH Terms:
Myocardial Infarction*/metabolism
Myocardial Ischemia*
Heart Failure*
Mice ; Animals ; Toll-Like Receptor 9/metabolism ; Adaptor Proteins, Signal Transducing/metabolism ; Src Homology 2 Domain-Containing, Transforming Protein 1/metabolism ; NF-kappa B/metabolism ; Inflammation ; Mice, Knockout ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Lack of GPR180 ameliorates hepatic lipid depot via downregulation of mTORC1 signaling.
Autorzy:
Yoshida K; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Yokota K; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Watanabe K; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Tsuda H; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Matsumoto A; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan.
Mizukami H; Division of Genetic Therapeutics, Center for Molecular Medicine, Jichi Medical School, Tochigi, Japan.
Iwamoto S; Division of Human Genetics, Center for Molecular Medicine, Jichi Medical University, 3311-1 Yakushiji, Shimotsuke, Tochigi, 329-0498, Japan. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 01; Vol. 13 (1), pp. 1843. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/metabolism
Humans ; Animals ; Mice ; Down-Regulation ; Genome-Wide Association Study ; Liver/metabolism ; Receptors, G-Protein-Coupled/genetics ; Receptors, G-Protein-Coupled/metabolism ; Lipid Metabolism ; Lipids ; Mechanistic Target of Rapamycin Complex 1/metabolism ; Diet, High-Fat/adverse effects ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Cell type specific IL-27p28 (IL-30) deletion in mice uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation.
Autorzy:
Kim D; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Kim S; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Kang MS; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.
Yin Z; Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and Treatment, Zhuhai Institute of Translational Medicine, Zhuhai People's Hospital Affiliated with Jinan University, Jinan University, Zhuhai, China.; The Biomedical Translational Research Institute, Faculty of Medical Science, Jinan University, Guangzhou, China.
Min B; Department of Microbiology and Immunology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 01; Vol. 13 (1), pp. 1812. Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Encephalomyelitis, Autoimmune, Experimental*/pathology
Interleukin-27*
Mice ; Animals ; T-Lymphocytes ; Cytokines/metabolism ; Inflammation/genetics ; Inflammation/pathology ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Calcipotriol Attenuates Form Deprivation Myopia Through a Signaling Pathway Parallel to TGF-β2-Induced Increases in Collagen Expression.
Autorzy:
Jiao S; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Reinach PS; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Huang C; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Yu L; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhuang H; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Ran H; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Zhao F; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences, Wenzhou, Zhejiang, China.; Oujiang Laboratory, Zhejiang Lab for Regenerative Medicine, Vision and Brain Health, Wenzhou, Zhejiang, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.
Srinivasalu N; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
Qu J; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Oujiang Laboratory, Zhejiang Lab for Regenerative Medicine, Vision and Brain Health, Wenzhou, Zhejiang, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.
Zhou X; School of Optometry and Ophthalmology and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; State Key Laboratory of Ophthalmology, Optometry and Visual Science, Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.; Research Unit of Myopia Basic Research and Clinical Prevention and Control, Chinese Academy of Medical Sciences, Wenzhou, Zhejiang, China.; Oujiang Laboratory, Zhejiang Lab for Regenerative Medicine, Vision and Brain Health, Wenzhou, Zhejiang, China.; National Clinical Research Center for Ocular Diseases, Wenzhou, Zhejiang, China.
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Źródło:
Investigative ophthalmology & visual science [Invest Ophthalmol Vis Sci] 2023 Feb 01; Vol. 64 (2), pp. 2.
Typ publikacji:
Journal Article
MeSH Terms:
Transforming Growth Factor beta2*/pharmacology
Transforming Growth Factor beta2*/metabolism
Myopia*/genetics
Humans ; Animals ; Mice ; Mice, Inbred C57BL ; Collagen/metabolism ; Calcitriol/pharmacology ; Calcitriol/metabolism ; Signal Transduction ; Sclera/metabolism
Czasopismo naukowe
Tytuł:
Ethanol-induced ceramide production causes neuronal apoptosis by increasing MCL-1S-mediated ER-mitochondria contacts.
Autorzy:
Lim JR; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Chae CW; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Park JY; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Jung YH; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Yoon JH; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Kim MJ; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea.
Lee HJ; Laboratory of Veterinary Physiology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea; Institute for Stem Cell & Regenerative Medicine (ISCRM), Chungbuk National University, Cheongju, Chungbuk, 28644, Republic of Korea.
Choi GE; Laboratory of Veterinary Biochemistry, College of Veterinary Medicine, Jeju National University, Jeju, 63243, Republic of Korea.
Han HJ; Department of Veterinary Physiology, College of Veterinary Medicine, Research Institute for Veterinary Science, and BK21 Four Future Veterinary Medicine Leading Education & Research Center, Seoul National University, Seoul, 08826, Republic of Korea. Electronic address: .
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Źródło:
Neurobiology of disease [Neurobiol Dis] 2023 Feb; Vol. 177, pp. 106009. Date of Electronic Publication: 2023 Jan 20.
Typ publikacji:
Journal Article
MeSH Terms:
Ceramides*/metabolism
Neuroblastoma*/metabolism
Humans ; Mice ; Animals ; Ethanol/pharmacology ; Calcium/metabolism ; Mice, Inbred C57BL ; Apoptosis ; Mitochondria/metabolism ; Endoplasmic Reticulum/metabolism ; Serine-Arginine Splicing Factors
Czasopismo naukowe
Tytuł:
IFN-γR/STAT1 signaling in recipient hematopoietic antigen-presenting cells suppresses graft-versus-host disease.
Autorzy:
Lu C; Columbia Center for Translational Immunology and.
Ma H; Columbia Center for Translational Immunology and.
Song L; Columbia Center for Translational Immunology and.
Wang H; Columbia Center for Translational Immunology and.
Wang L; Columbia Center for Translational Immunology and.
Li S; Division of Hematology-Oncology, Columbia University, New York, New York, USA.
Lagana SM; Department of Pathology and Cell Biology, Columbia University, New York, New York, USA.
Sepulveda AR; Department of Pathology, George Washington University School of Medicine and Health Sciences, Washington DC, USA.
Hoebe K; Department of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA.; Janssen Research and Development, Spring House, Pennsylvania, USA.
Pan SS; Janssen Research and Development, Spring House, Pennsylvania, USA.
Yang YG; Columbia Center for Translational Immunology and.
Lentzsch S; Division of Hematology-Oncology, Columbia University, New York, New York, USA.
Mapara MY; Columbia Center for Translational Immunology and.; Division of Hematology-Oncology, Columbia University, New York, New York, USA.
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Źródło:
The Journal of clinical investigation [J Clin Invest] 2023 Feb 01; Vol. 133 (3). Date of Electronic Publication: 2023 Feb 01.
Typ publikacji:
Journal Article
MeSH Terms:
Antigen-Presenting Cells*
Graft vs Host Disease*/genetics
Mice ; Humans ; Animals ; Receptors, Interferon/genetics ; Signal Transduction ; Bone Marrow Transplantation/adverse effects ; Mice, Inbred C57BL ; STAT1 Transcription Factor/genetics ; STAT1 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł:
Intracellular calprotectin (S100A8/A9) facilitates DNA damage responses and promotes apoptosis in head and neck squamous cell carcinoma.
Autorzy:
Argyris PP; Department of Biochemistry, Molecular Biology and Biophysics, University of Minnesota, Minneapolis, MN, USA; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Institute for Molecular Virology, University of Minnesota, Minneapolis, MN, USA; Center for Genome Engineering, University of Minnesota, Minneapolis, MN, USA; Howard Hughes Medical Institute, University of Minnesota, Minneapolis, MN, USA; Division of Oral and Maxillofacial Pathology, School of Dentistry, University of Minnesota, Minneapolis, MN, USA. Electronic address: .
Saavedra F; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Malz C; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Stone IA; Department of Immunology, Microbiology and Virology, School of Medicine and Dentistry, University of Rochester, Rochester, NY, USA.
Wei Y; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Boyle WS; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Johnstone KF; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA.
Khammanivong A; Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, University of Minnesota, St. Paul, MN, USA.
Herzberg MC; Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA. Electronic address: .
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Źródło:
Oral oncology [Oral Oncol] 2023 Feb; Vol. 137, pp. 106304. Date of Electronic Publication: 2023 Jan 04.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma*
Head and Neck Neoplasms*/genetics
Animals ; Humans ; Mice ; Apoptosis ; Calgranulin A/genetics ; Calgranulin A/metabolism ; Calgranulin B/metabolism ; Leukocyte L1 Antigen Complex/metabolism ; Mice, Inbred C57BL ; Squamous Cell Carcinoma of Head and Neck
Czasopismo naukowe
Tytuł:
Effect of Sustained Systemic Administration of Ginger (Z officinale) Rhizome Extracts on Salivary Flow in Mice.
Autorzy:
Kan CY; School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
H'ng JX; School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
Goh A; School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia.
Smales F; School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
Tan EL; School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Zhang S; School of Postgraduate Studies, International Medical University, Kuala Lumpur, Malaysia.
Pichika MR; Department of Pharmaceutical Chemistry, School of Pharmacy, International Medical University, Kuala Lumpur, Malaysia.
Parolia A; School of Dentistry, International Medical University, Kuala Lumpur, Malaysia. Electronic address: abhishek_.
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Źródło:
International dental journal [Int Dent J] 2023 Feb; Vol. 73 (1), pp. 63-70. Date of Electronic Publication: 2022 Jun 18.
Typ publikacji:
Journal Article
MeSH Terms:
Ginger*
Mice ; Humans ; Animals ; Rhizome ; Dimethyl Sulfoxide/pharmacology ; Methanol ; Pilocarpine ; Mice, Inbred C57BL ; Plant Extracts/pharmacology
Czasopismo naukowe
Tytuł:
Interleukin-6 initiates muscle- and adipose tissue wasting in a novel C57BL/6 model of cancer-associated cachexia.
Autorzy:
Pototschnig I; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Feiler U; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Diwoky C; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Vesely PW; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Rauchenwald T; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Paar M; Division of Physiological Chemistry, Otto-Loewi Research Center, Medical University of Graz, Graz, Austria.
Bakiri L; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.
Pajed L; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Hofer P; Institute of Molecular Biosciences, University of Graz, Graz, Austria.
Kashofer K; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.
Sukhbaatar N; Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
Schoiswohl G; Department of Pharmacology and Toxicology, University of Graz, Graz, Austria.
Weichhart T; Institute of Medical Genetics, Medical University of Vienna, Vienna, Austria.
Hoefler G; Diagnostic and Research Institute of Pathology, Medical University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.
Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute of Artificial Intelligence, Center for Medical Statistics, Informatics, and Intelligent Systems, Medical University of Vienna, Vienna, Austria.
Pichler M; Division of Oncology, Medical University of Graz, Austria.
Wagner EF; Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria.; Department of Dermatology, Medical University of Vienna, Vienna, Austria.
Zechner R; Institute of Molecular Biosciences, University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.; Field of Excellence BioHealth - University of Graz, Graz, Austria.
Schweiger M; Institute of Molecular Biosciences, University of Graz, Graz, Austria.; BioTechMed-Graz, Graz, Austria.; Field of Excellence BioHealth - University of Graz, Graz, Austria.
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Źródło:
Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2023 Feb; Vol. 14 (1), pp. 93-107. Date of Electronic Publication: 2022 Nov 09.
Typ publikacji:
Journal Article
MeSH Terms:
Cachexia*/pathology
Fibrosarcoma*/complications
Male ; Female ; Mice ; Animals ; Interleukin-6/metabolism ; Mice, Inbred C57BL ; Adipose Tissue/pathology ; Muscular Atrophy/pathology ; Muscle Fibers, Skeletal/metabolism
Czasopismo naukowe
Tytuł:
Role of liquid fructose/sucrose in regulating the hepatic transcriptome in a high-fat Western diet model of NAFLD.
Autorzy:
Luo Y; Department of Nutritional Sciences.
Woodie LN; Department of Nutritional Sciences.
Graff EC; Department of Pathobiology; Boshell Metabolic Diseases and Diabetes Program, Auburn University, Auburn, Alabama, USA.
Zhang J; Department of Nutritional Sciences.
Fowler S; Department of Nutritional Sciences.
Wang X; Department of Pathobiology.
Wang X; Department of Pathobiology; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama, USA.
O'Neill AM; Department of Nutritional Sciences.
Greene MW; Department of Nutritional Sciences; Boshell Metabolic Diseases and Diabetes Program, Auburn University, Auburn, Alabama, USA. Electronic address: .
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Źródło:
The Journal of nutritional biochemistry [J Nutr Biochem] 2023 Feb; Vol. 112, pp. 109174. Date of Electronic Publication: 2022 Oct 22.
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/genetics
Non-alcoholic Fatty Liver Disease*/metabolism
Humans ; Mice ; Animals ; Transcriptome ; Fructose/adverse effects ; Fructose/metabolism ; Sucrose/adverse effects ; Sucrose/metabolism ; Diet, Western/adverse effects ; Liver/metabolism ; Diet, High-Fat/adverse effects ; Obesity/metabolism ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe

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