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Tytuł :
CVN-AD Alzheimer's mice show premature reduction in neurovascular coupling in response to spreading depression and anoxia compared to aged controls.
Autorzy :
Turner DA; Neurosurgery, Box 3807, Duke University Medical Center, Durham, North Carolina, 27710, USA.; Neurobiology, Box 3209, Duke University Medical Center, Durham, North Carolina, 27710, USA.; Biomedical Engineering, Box 90281, Duke University, Durham, North Carolina, 27708, USA.; Research and Surgery Services, Durham VA Medical Center, 508 Fulton Street, Durham, North Carolina, 27705, USA.
Degan S; Neurosurgery, Box 3807, Duke University Medical Center, Durham, North Carolina, 27710, USA.; Research and Surgery Services, Durham VA Medical Center, 508 Fulton Street, Durham, North Carolina, 27705, USA.
Hoffmann U; Anesthesiology, Box 3094, Duke University Medical Center, Durham, North Carolina, 27710, USA.
Galeffi F; Neurosurgery, Box 3807, Duke University Medical Center, Durham, North Carolina, 27710, USA.; Research and Surgery Services, Durham VA Medical Center, 508 Fulton Street, Durham, North Carolina, 27705, USA.
Colton CA; Neurology, Box 2900, Duke University Medical Center, Durham, North Carolina, 27710, USA.
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Źródło :
Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2021 Jul; Vol. 17 (7), pp. 1109-1120. Date of Electronic Publication: 2021 Mar 03.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
Mice, Inbred C57BL*
Neurovascular Coupling*
Cerebrovascular Circulation/*physiology
Depression/*physiopathology
Hypoxia/*physiopathology
Aging ; Alzheimer Disease/pathology ; Animals ; Female ; Hemodynamics/physiology ; Humans ; Male ; Mice
Czasopismo naukowe
Tytuł :
Cartilage Oligomeric Matrix Protein Induced Arthritis-A New Model for Rheumatoid Arthritis in the C57BL/6 Mouse.
Autorzy :
Zhao Y; Department of Endocrinology, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Urbonaviciute V; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Xu B; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Cai W; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Sener Z; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Ge C; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
Holmdahl R; Medical Inflammation Research, Department of Medical Biochemistry and Biophysics, Karolinska Institute, Stockholm, Sweden.
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Źródło :
Frontiers in immunology [Front Immunol] 2021 Feb 23; Vol. 12, pp. 631249. Date of Electronic Publication: 2021 Feb 23 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice, Inbred C57BL*
Arthritis, Experimental/*immunology
Arthritis, Experimental/*physiopathology
Cartilage Oligomeric Matrix Protein/*administration & dosage
Animals ; Cartilage Oligomeric Matrix Protein/immunology ; Epitopes, T-Lymphocyte/immunology ; Genes, MHC Class II ; Injections, Intradermal ; Male ; Mice ; Peptides/administration & dosage ; Peptides/chemical synthesis
Czasopismo naukowe
Tytuł :
Environmental enrichment influences novelty reactivity, novelty preference, and anxiety via distinct genetic mechanisms in C57BL/6J and DBA/2J mice.
Autorzy :
Dickson PE; Department of Psychology, University of Memphis, 400 Innovation Drive, Memphis, TN, 38111, USA. .; Department of Biomedical Sciences, Joan C. Edwards School of Medicine, Marshall University, 1700 3rd Ave., Huntington, WV, 25703, USA. .
Mittleman G; Department of Psychology, University of Memphis, 400 Innovation Drive, Memphis, TN, 38111, USA.; Department of Psychological Science, Ball State University, North Quad (NQ), room 104, Muncie, IN, 47306, USA.
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Źródło :
Scientific reports [Sci Rep] 2021 Feb 16; Vol. 11 (1), pp. 3928. Date of Electronic Publication: 2021 Feb 16.
Typ publikacji :
Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Exploratory Behavior*
Anxiety/*genetics
Mice, Inbred C57BL/*psychology
Mice, Inbred DBA/*psychology
Social Isolation/*psychology
Animals ; Behavior, Addictive ; Female ; Housing, Animal ; Male ; Mice, Inbred C57BL/genetics ; Mice, Inbred DBA/genetics ; Sex Factors
Czasopismo naukowe
Tytuł :
Xuanfei Baidu Decoction protects against macrophages induced inflammation and pulmonary fibrosis via inhibiting IL-6/STAT3 signaling pathway.
Autorzy :
Wang Y; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Sang X; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Shao R; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Qin H; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Chen X; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Xue Z; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Li L; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, 301617, China.
Wang Y; School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Zhu Y; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Chang Y; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Tianjin Key Laboratory of Phytochemistry and Pharmaceutical Analysis, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China.
Gao X; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, 301617, China.
Zhang B; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, 301617, China.
Zhang H; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Key Laboratory of Pharmacology of Traditional Chinese Medical Formulae, Tianjin University of Traditional Chinese Medicine, Ministry of Education, Tianjin, 301617, China. Electronic address: .
Yang J; State Key Laboratory of Component-based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China; Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin, 301617, China. Electronic address: .
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Źródło :
Journal of ethnopharmacology [J Ethnopharmacol] 2022 Jan 30; Vol. 283, pp. 114701. Date of Electronic Publication: 2021 Oct 01.
Typ publikacji :
Journal Article
MeSH Terms :
Drugs, Chinese Herbal*/pharmacology
Drugs, Chinese Herbal*/therapeutic use
SARS-CoV-2*
COVID-19/*drug therapy
Inflammation/*drug therapy
Macrophages/*drug effects
Signal Transduction/*drug effects
Animals ; Cell Survival/drug effects ; Fibroblasts/drug effects ; Gene Expression Regulation/drug effects ; Gene Regulatory Networks ; Humans ; Interleukin-6/antagonists & inhibitors ; Interleukin-6/genetics ; Interleukin-6/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; NIH 3T3 Cells ; Phytotherapy ; Pulmonary Fibrosis/pathology ; Pulmonary Fibrosis/prevention & control ; RAW 264.7 Cells ; STAT3 Transcription Factor/antagonists & inhibitors ; STAT3 Transcription Factor/genetics ; STAT3 Transcription Factor/metabolism
Czasopismo naukowe
Tytuł :
Effects of long-term social isolation on central, behavioural and metabolic parameters in middle-aged mice.
Autorzy :
Benfato ID; Interdisciplinary Graduate Program in Health Sciences, Federal University of Sao Paulo (UNIFESP), Brazil.
Quintanilha ACS; Interdisciplinary Graduate Program in Health Sciences, Federal University of Sao Paulo (UNIFESP), Brazil.
Henrique JS; Neurology / Neuroscience Graduate Program, Federal University of Sao Paulo (UNIFESP), Brazil.
Souza MA; Interdisciplinary Graduate Program in Health Sciences, Federal University of Sao Paulo (UNIFESP), Brazil.
Rosário BDA; Interdisciplinary Graduate Program in Health Sciences, Federal University of Sao Paulo (UNIFESP), Brazil.
Beserra Filho JIA; Pharmacology Graduate Program, Federal University of Sao Paulo (UNIFESP), Brazil.
Santos RLO; Undergraduate Physical Education, Federal University of Sao Paulo (UNIFESP), Brazil.
Ribeiro AM; Department of Biosciences, Institute of Health and Society, Federal University of Sao Paulo (UNIFESP), Brazil.
Le Sueur Maluf L; Department of Biosciences, Institute of Health and Society, Federal University of Sao Paulo (UNIFESP), Brazil.
de Oliveira CAM; Department of Biosciences, Institute of Health and Society, Federal University of Sao Paulo (UNIFESP), Brazil. Electronic address: .
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Źródło :
Behavioural brain research [Behav Brain Res] 2022 Jan 24; Vol. 417, pp. 113630. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article; Randomized Controlled Trial, Veterinary; Research Support, Non-U.S. Gov't
MeSH Terms :
COVID-19*/prevention & control
Feeding Behavior*/physiology
Locomotion*/physiology
Social Isolation*
Anxiety/*etiology
Hippocampus/*metabolism
Memory Disorders/*etiology
Age Factors ; Animals ; Behavior, Animal/physiology ; Brain-Derived Neurotrophic Factor ; Disease Models, Animal ; Housing, Animal ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Proto-Oncogene Proteins c-fos/metabolism
Czasopismo naukowe
Tytuł :
Intestinal Claudin-7 deficiency impacts the intestinal microbiota in mice with colitis.
Autorzy :
Ding Y; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China.
Wang K; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China.
Xu C; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China.; Department of Hepato-Pancreato-Biliary Surgery, Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education/Beijing, Peking University Cancer Hospital and Institute, Beijing, 100142, China.
Hao M; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China.
Li H; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China.
Ding L; Department of Oncology, Beijing Shijitan Hospital, Capital Medical University, Tieyilu 10, Yangfangdian, Haidian District, Beijing, 100038, China. .
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Źródło :
BMC gastroenterology [BMC Gastroenterol] 2022 Jan 17; Vol. 22 (1), pp. 24. Date of Electronic Publication: 2022 Jan 17.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis*/chemically induced
Gastrointestinal Microbiome*
Animals ; Claudins/genetics ; Colon ; Dextran Sulfate ; Disease Models, Animal ; In Situ Hybridization, Fluorescence ; Intestinal Mucosa ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; RNA, Ribosomal, 16S/genetics
Czasopismo naukowe
Tytuł :
Homeostasis effects of fermented Maillard reaction products by Lactobacillus gasseri 4M13 in dextran sulfate sodium-induced colitis mice.
Autorzy :
Jeong YJ; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Kim DH; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
Lee KW; Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul, Republic of Korea.
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Źródło :
Journal of the science of food and agriculture [J Sci Food Agric] 2022 Jan 15; Vol. 102 (1), pp. 434-444. Date of Electronic Publication: 2021 Jul 06.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis/*drug therapy
Glycation End Products, Advanced/*administration & dosage
Lactobacillus gasseri/*metabolism
Probiotics/*administration & dosage
Animals ; Anti-Inflammatory Agents/administration & dosage ; Colitis/chemically induced ; Colitis/immunology ; Colitis/physiopathology ; Colon/drug effects ; Colon/immunology ; Dextran Sulfate/adverse effects ; Disease Models, Animal ; Galactose/metabolism ; Glycation End Products, Advanced/metabolism ; Homeostasis/drug effects ; Humans ; Interleukin-10/genetics ; Interleukin-10/immunology ; Interleukin-6/genetics ; Interleukin-6/immunology ; Intestinal Mucosa/drug effects ; Intestinal Mucosa/immunology ; Male ; Mice ; Mice, Inbred C57BL ; Tight Junctions/genetics ; Tight Junctions/immunology ; Tumor Necrosis Factor-alpha/genetics ; Tumor Necrosis Factor-alpha/immunology ; Whey Proteins/metabolism
Czasopismo naukowe
Tytuł :
Involvement of aldehyde oxidase in the metabolism of aromatic and aliphatic aldehyde-odorants in the mouse olfactory epithelium.
Autorzy :
Takaoka N; Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; Research Fellow of Japan Society for the Promotion of Science, Japan; School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.
Sanoh S; Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan. Electronic address: .
Ohta S; Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan; School of Pharmaceutical Sciences, Wakayama Medical University, Wakayama, Japan.
Esmaeeli M; Institute of Biochemistry and Biology, University of Potsdam, Germany.
Leimkühler S; Institute of Biochemistry and Biology, University of Potsdam, Germany.
Kurosaki M; Laboratory of Molecular Biology, Istituto di Ricerche Farmacologiche 'Mario Negri', Italy.
Terao M; Laboratory of Molecular Biology, Istituto di Ricerche Farmacologiche 'Mario Negri', Italy.
Garattini E; Laboratory of Molecular Biology, Istituto di Ricerche Farmacologiche 'Mario Negri', Italy.
Kotake Y; Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2022 Jan 15; Vol. 715, pp. 109099. Date of Electronic Publication: 2021 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Odorants*
Aldehyde Oxidase/*metabolism
Aldehyde Oxidoreductases/*metabolism
Aldehydes/*metabolism
Olfactory Mucosa/*metabolism
Aldehyde Oxidase/antagonists & inhibitors ; Aldehyde Oxidoreductases/antagonists & inhibitors ; Aldehydes/chemistry ; Animals ; Enzyme Inhibitors/pharmacology ; Female ; Male ; Mice, Inbred C57BL ; Olfactory Mucosa/drug effects ; Oxidation-Reduction/drug effects ; Smell/drug effects
Czasopismo naukowe
Tytuł :
Insights into the effects of difenoconazole on the livers in male mice at the biochemical and transcriptomic levels.
Autorzy :
Zhang H; Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Qian M; Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Wang J; Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Yang G; Zhejiang Province Key Laboratory for Food Safety, Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, China.
Weng Y; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Jin C; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China.
Li Y; Zhejiang Institute for Food and Drug Control, Hangzhou, Zhejiang, China.
Jin Y; College of Biotechnology and Bioengineering, Zhejiang University of Technology, Hangzhou 310032, China. Electronic address: .
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Źródło :
Journal of hazardous materials [J Hazard Mater] 2022 Jan 15; Vol. 422, pp. 126933. Date of Electronic Publication: 2021 Aug 17.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Transcriptome*
Triazoles*/toxicity
Animals ; Dioxolanes ; Liver ; Male ; Mice ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł :
Chronic stress induces platinum and Niraparib resistance in mouse models of ovarian cancer.
Autorzy :
Liu M; Department of Gynecologic Oncology, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, PR China.
Zhou X; Department of Gynecologic Oncology, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, PR China.
Sun L; Department of Gynecology and Obstetrics, Shaoyang Central Hospital, Shaoyang 422000, PR China.
Tan S; Department of Gynecology and Obstetrics, The First People's Hospital of Huaihua, the Affiliated Huaihua Hospital of University of South China, Huaihua 418000, PR China.
Liu T; Department of Gynecology and Obstetrics, The First People's Hospital of Changde, Changde 415000, PR China.
Xiao W; Department of Gynecology and Obstetrics, The First People's Hospital of Yueyang, Yueyang, 414000, PR China.
Tang J; Department of Gynecologic Oncology, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, PR China; Hunan Gynecologic Cancer Research Center, Hunan Cancer Hospital, the Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha 410013, PR China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2022 Jan 15; Vol. 410 (2), pp. 112935. Date of Electronic Publication: 2021 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Drug Resistance, Neoplasm*/drug effects
Drug Resistance, Neoplasm*/genetics
Indazoles/*therapeutic use
Ovarian Neoplasms/*drug therapy
Piperidines/*therapeutic use
Platinum/*therapeutic use
Stress, Psychological/*complications
Animals ; Cell Line, Tumor ; Disease Models, Animal ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Regulatory Networks/drug effects ; Humans ; Indazoles/pharmacology ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Middle Aged ; Models, Biological ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/pathology ; Piperidines/pharmacology ; Platinum/pharmacology
Czasopismo naukowe
Tytuł :
Long non-coding RNA MALAT1 silencing elevates microRNA-26a-5p to ameliorate myocardial injury in sepsis by reducing regulator of calcineurin 2.
Autorzy :
Luo Y; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Xu H; Department of Nephrology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Yang Z; President's Office, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Lin X; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Zhao F; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Huang Y; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Wang Y; The First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Yang X; Clinical Laboratory, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Li H; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Wang L; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Wen M; Department of Intensive Care Unit, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
Xian S; President's Office, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510405, China. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2022 Jan 15; Vol. 715, pp. 109047. Date of Electronic Publication: 2021 Oct 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Intracellular Signaling Peptides and Proteins/*metabolism
MicroRNAs/*metabolism
Myocardial Ischemia/*physiopathology
RNA, Long Noncoding/*metabolism
Sepsis/*physiopathology
Animals ; Apoptosis/drug effects ; Apoptosis/physiology ; Cell Line ; Cell Proliferation/drug effects ; Cell Proliferation/physiology ; Down-Regulation/drug effects ; Down-Regulation/physiology ; Inflammation/chemically induced ; Inflammation/physiopathology ; Lipopolysaccharides/pharmacology ; Mice, Inbred C57BL ; Myocardial Ischemia/etiology ; Myocytes, Cardiac/drug effects ; Myocytes, Cardiac/metabolism ; Oxidative Stress/drug effects ; Oxidative Stress/physiology ; Rats ; Sepsis/complications ; Up-Regulation/drug effects ; Up-Regulation/physiology
Czasopismo naukowe
Tytuł :
Cxcl10 deficiency attenuates renal interstitial fibrosis through regulating epithelial-to-mesenchymal transition.
Autorzy :
Gao J; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China; Department of Nephrology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jingwu Road 324, Jinan, 250021, China.
Wu L; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China.
Zhao Y; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China.
Hong Q; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China.
Feng Z; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China.
Chen X; Department of Nephrology, Chinese PLA General Hospital, Chinese PLA Institute of Nephrology, Beijing Key Laboratory of Kidney Disease, State Key Laboratory of Kidney Diseases, National Clinical Research Center for Kidney Diseases, Fuxing Road 28, Beijing, 100853, China. Electronic address: .
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Źródło :
Experimental cell research [Exp Cell Res] 2022 Jan 15; Vol. 410 (2), pp. 112965. Date of Electronic Publication: 2021 Dec 08.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Epithelial-Mesenchymal Transition*
Chemokine CXCL10/*deficiency
Kidney Diseases/*metabolism
Kidney Diseases/*pathology
Animals ; Cell Proliferation ; Chemokine CXCL10/metabolism ; Fibrosis ; Humans ; Kidney/pathology ; Kidney/physiopathology ; Mice, Inbred C57BL ; Mice, Knockout ; Ureteral Obstruction/pathology
Czasopismo naukowe
Tytuł :
Effect of Coffee against MPTP-Induced Motor Deficits and Neurodegeneration in Mice Via Regulating Gut Microbiota.
Autorzy :
Liu J; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Zhang Y; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Ye T; Department of Geriatrics, the Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, China.
Yu Q; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Yu J; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Yuan S; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Gao X; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Wan X; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Zhang R; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Han W; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang 325035, China.
Zhang Y; Department of Neurology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Jan 12; Vol. 70 (1), pp. 184-195. Date of Electronic Publication: 2022 Jan 04.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*
Neuroprotective Agents*
1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine ; Animals ; Coffee ; Disease Models, Animal ; Dopaminergic Neurons ; Mice ; Mice, Inbred C57BL ; RNA, Ribosomal, 16S
Czasopismo naukowe
Tytuł :
Sweeteners Maintain Epithelial Barrier Function Through the miR-15b/RECK/MMP-9 Axis, Remodel Microbial Homeostasis, and Attenuate Dextran Sodium Sulfate-Induced Colitis in Mice.
Autorzy :
Zhang X; School of Medicine, Nankai University, Tianjin 300071, China.; College of Food Science and Technology, Hebei Agricultural University, Baoding 071000, China.
Gu J; School of Medicine, Nankai University, Tianjin 300071, China.
Zhao C; School of Medicine, Nankai University, Tianjin 300071, China.
Hu Y; School of Medicine, Nankai University, Tianjin 300071, China.
Zhang B; School of Medicine, Nankai University, Tianjin 300071, China.
Wang J; School of Medicine, Nankai University, Tianjin 300071, China.
Lv H; School of Medicine, Nankai University, Tianjin 300071, China.
Ji X; School of Medicine, Nankai University, Tianjin 300071, China.
Wang S; School of Medicine, Nankai University, Tianjin 300071, China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Jan 12; Vol. 70 (1), pp. 171-183. Date of Electronic Publication: 2021 Dec 28.
Typ publikacji :
Journal Article
MeSH Terms :
Colitis*/chemically induced
Colitis*/drug therapy
Colitis*/genetics
MicroRNAs*/genetics
Animals ; Colon ; Dextran Sulfate/adverse effects ; Disease Models, Animal ; Homeostasis ; Matrix Metalloproteinase 9 ; Mice ; Mice, Inbred C57BL ; Sulfates ; Sweetening Agents
Czasopismo naukowe
Tytuł :
Apple Polyphenols Extracts Ameliorate High Carbohydrate Diet-Induced Body Weight Gain by Regulating the Gut Microbiota and Appetite.
Autorzy :
Wang X; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.
Liu F; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.
Cui Y; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.
Yin Y; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.
Li S; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.
Li X; School of Public Health, Medical College of Soochow University, 199 Renai Road, Suzhou 215123, Jiangsu, P. R. China.; Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, School of Public Health, Soochow University, Suzhou 215123, Jiangsu, P. R. China.
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Źródło :
Journal of agricultural and food chemistry [J Agric Food Chem] 2022 Jan 12; Vol. 70 (1), pp. 196-210. Date of Electronic Publication: 2021 Dec 22.
Typ publikacji :
Journal Article
MeSH Terms :
Gastrointestinal Microbiome*
Animals ; Appetite ; Body Weight ; Carbohydrates ; Diet, High-Fat ; Male ; Mice ; Mice, Inbred C57BL ; Plant Extracts ; Polyphenols ; Weight Gain
Czasopismo naukowe
Tytuł :
Integrative omics analysis identifies biomarkers of idiopathic pulmonary fibrosis.
Autorzy :
Zheng P; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Sun S; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Wang J; National Joint Local Engineering Laboratory for Cell Engineering and Biomedicine Technique, Guizhou Province Key Laboratory of Regenerative Medicine, Key Laboratory of Adult Stem Cell Translational Research (Chinese Academy of Medical Sciences), Guizhou Medical University, Guizhou, 550025, China.
Cheng ZJ; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Lei KC; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Xue M; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Zhang T; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China.
Huang H; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China.
Zhang XD; Faculty of Health Sciences, University of Macau, Taipa, Macau SAR, China. .
Sun B; Department of Allergy and Clinical Immunology, State Key Laboratory of Respiratory Disease, National Clinical Research Centre for Respiratory Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, 510120, China. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Jan 11; Vol. 79 (1), pp. 66. Date of Electronic Publication: 2022 Jan 11.
Typ publikacji :
Journal Article
MeSH Terms :
Butyrophilins/*genetics
Extracellular Matrix/*metabolism
Idiopathic Pulmonary Fibrosis/*genetics
Idiopathic Pulmonary Fibrosis/*pathology
Myelin and Lymphocyte-Associated Proteolipid Proteins/*genetics
Animals ; Biomarkers/analysis ; Bleomycin/toxicity ; Cell Differentiation/genetics ; Cell Proliferation/genetics ; Disease Models, Animal ; Female ; Gene Expression Profiling ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Proteome/genetics ; Proteomics ; RNA-Seq ; Transcriptome/genetics ; Wound Healing/genetics
Czasopismo naukowe
Tytuł :
Migraine-relevant sex-dependent activation of mouse meningeal afferents by TRPM3 agonists.
Autorzy :
Krivoshein G; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland.
Tolner EA; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Amjm VDM; Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands.; Department of Neurology, Leiden University Medical Center, Leiden, The Netherlands.
Giniatullin RA; A.I.Virtanen Institute for Molecular Sciences, University of Eastern Finland, Kuopio, Finland. .; Laboratory of Neurobiology, Kazan Federal University, Kazan, Russia. .
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Źródło :
The journal of headache and pain [J Headache Pain] 2022 Jan 10; Vol. 23 (1), pp. 4. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji :
Journal Article
MeSH Terms :
Migraine Disorders*
TRPM Cation Channels*/agonists
Animals ; Female ; Ion Channels ; Male ; Meninges ; Mice ; Mice, Inbred C57BL ; TRPV Cation Channels ; Trigeminal Nerve
Czasopismo naukowe
Tytuł :
Secretogranin III stringently regulates pathological but not physiological angiogenesis in oxygen-induced retinopathy.
Autorzy :
Dai C; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
Waduge P; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
Ji L; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
Huang C; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
He Y; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.
Tian H; Everglades Biopharma, LLC, Houston, TX, USA.
Zuniga-Sanchez E; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.
Bhatt A; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.; Texas Children Hospital, Baylor College of Medicine, Houston, TX, USA.
Pang IH; Department of Pharmaceutical Sciences, North Texas Eye Research Institute, University of North Texas, Fort Worth, TX, USA.
Su G; Department of Ophthalmology, The Second Hospital of Jilin University, #218 Ziqiang Street, Changchun, Jilin, China.
Webster KA; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA.; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA.; Everglades Biopharma, LLC, Houston, TX, USA.
Li W; Cullen Eye Institute, Department of Ophthalmology, Baylor College of Medicine, Houston, TX, USA. .; Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Jan 10; Vol. 79 (1), pp. 63. Date of Electronic Publication: 2022 Jan 10.
Typ publikacji :
Journal Article
MeSH Terms :
Angiogenesis Inhibitors/*pharmacology
Chromogranins/*immunology
Chromogranins/*metabolism
Neovascularization, Pathologic/*genetics
Retinal Neovascularization/*pathology
Retinopathy of Prematurity/*pathology
Animals ; Capillaries/metabolism ; Chromogranins/antagonists & inhibitors ; Chromogranins/genetics ; Disease Models, Animal ; Immunoglobulin Fab Fragments/immunology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Oxygen/adverse effects ; Receptors, Vascular Endothelial Growth Factor ; Recombinant Fusion Proteins/pharmacology ; Retinal Neovascularization/genetics ; Vascular Endothelial Growth Factor A/antagonists & inhibitors
Czasopismo naukowe
Tytuł :
Host glyceraldehyde-3-phosphate dehydrogenase-mediated iron acquisition is hijacked by intraphagosomal Mycobacterium tuberculosis.
Autorzy :
Patidar A; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Malhotra H; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Chaudhary S; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Kumar M; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Dilawari R; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Chaubey GK; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Dhiman A; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Modanwal R; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Talukdar S; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India.
Raje CI; National Institute of Pharmaceutical Education and Research, Phase X, Sector 67, SAS Nagar, Punjab, 160062, India.
Raje M; Institute of Microbial Technology, CSIR, Sector 39A, Chandigarh, 160036, India. .
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2022 Jan 09; Vol. 79 (1), pp. 62. Date of Electronic Publication: 2022 Jan 09.
Typ publikacji :
Journal Article
MeSH Terms :
Glyceraldehyde-3-Phosphate Dehydrogenases/*metabolism
Iron/*metabolism
Lactoferrin/*metabolism
Mycobacterium tuberculosis/*metabolism
Transferrin/*metabolism
Animals ; Biological Transport/physiology ; Cell Line, Tumor ; Humans ; L Cells ; Mice ; Mice, Inbred C57BL ; Phagosomes/metabolism ; THP-1 Cells ; Tuberculosis/pathology
Czasopismo naukowe
Tytuł :
Diverse risk-avoidance behaviors in DISC1 mice are associated with different neuronal firing patterns in BLA neurons.
Autorzy :
Zhou X; Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China; University of Chinese of Academy of Sciences, Beijing, 100049, China.
Xiao Q; Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China.
Tu J; Guangdong Provincial Key Laboratory of Brain Connectome and Behavior, CAS Key Laboratory of Brain Connectome and Manipulation, The Brain Cognition and Brain Disease Institute (BCBDI), Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen-Hong Kong Institute of Brain Science-Shenzhen Fundamental Research Institutions, Shenzhen, 518055, China; University of Chinese of Academy of Sciences, Beijing, 100049, China. Electronic address: .
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Źródło :
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2022 Jan 08; Vol. 587, pp. 107-112. Date of Electronic Publication: 2021 Nov 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Avoidance Learning/*physiology
Basolateral Nuclear Complex/*metabolism
Nerve Tissue Proteins/*genetics
Neurons/*metabolism
Action Potentials/physiology ; Animals ; Basolateral Nuclear Complex/pathology ; Female ; Gene Expression ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Nerve Tissue Proteins/deficiency ; Neurons/pathology ; Optogenetics/methods ; Patch-Clamp Techniques ; Photic Stimulation/methods ; Risk-Taking
Czasopismo naukowe

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