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Tytuł:
Elucidating ascorbate and aldarate metabolism pathway characteristics via integration of untargeted metabolomics and transcriptomics of the kidney of high-fat diet-fed obese mice.
Autorzy:
Liang H; Department of Basic Medical Sciences, Medical College, Qinghai University, Xining, Qinghai, China.
Song K; Endocrinology Department, Qinghai Provincial People's Hospital, Xining, Qinghai, China.; Qinghai University Affiliated People's Hospital, Xining, Qinghai, China.
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Źródło:
PloS one [PLoS One] 2024 Apr 11; Vol. 19 (4), pp. e0300705. Date of Electronic Publication: 2024 Apr 11 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Diet, High-Fat*/adverse effects
Kidney*/metabolism
Animals ; Mice ; Male ; Mice, Obese ; Mice, Inbred C57BL ; Obesity/etiology ; Obesity/metabolism ; Metabolomics ; Gene Expression Profiling
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Cyclophilin D knockout significantly prevents HCC development in a streptozotocin-induced mouse model of diabetes-linked NASH.
Autorzy:
Stauffer WT; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.
Bobardt M; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.
Ure DR; Hepion Pharmaceuticals, Edison, New Jersey, United States of America.
Foster RT; Hepion Pharmaceuticals, Edison, New Jersey, United States of America.
Gallay P; Department of Immunology & Microbiology, Scripps Research, La Jolla, California, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Apr 04; Vol. 19 (4), pp. e0301711. Date of Electronic Publication: 2024 Apr 04 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Carcinoma, Hepatocellular*/prevention & control
Carcinoma, Hepatocellular*/pathology
Diabetes Mellitus*/pathology
Liver Neoplasms*/genetics
Liver Neoplasms*/prevention & control
Liver Neoplasms*/drug therapy
Non-alcoholic Fatty Liver Disease*/pathology
Animals ; Humans ; Mice ; Cyclophilins/genetics ; Diet, High-Fat ; Disease Models, Animal ; Liver/pathology ; Mice, Inbred C57BL ; Peptidyl-Prolyl Isomerase F ; Streptozocin
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Whole transcriptome sequencing analyses of islets reveal ncRNA regulatory networks underlying impaired insulin secretion and increased β-cell mass in high fat diet-induced diabetes mellitus.
Autorzy:
Ma J; Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.; Center for Diabetes and Metabolism Research, West China Hospital, Sichuan University, Chengdu, China.
Gao R; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom.
Xie Q; Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.; Center for Diabetes and Metabolism Research, West China Hospital, Sichuan University, Chengdu, China.
Pan X; Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.; Center for Diabetes and Metabolism Research, West China Hospital, Sichuan University, Chengdu, China.
Tong N; Department of Endocrinology and Metabolism, West China Hospital, Sichuan University, Chengdu, China.; Center for Diabetes and Metabolism Research, West China Hospital, Sichuan University, Chengdu, China.
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Źródło:
PloS one [PLoS One] 2024 Apr 01; Vol. 19 (4), pp. e0300965. Date of Electronic Publication: 2024 Apr 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
RNA, Long Noncoding*/genetics
RNA, Long Noncoding*/metabolism
MicroRNAs*/genetics
MicroRNAs*/metabolism
Diabetes Mellitus*
Mice ; Animals ; Diet, High-Fat/adverse effects ; RNA, Circular/metabolism ; Insulin Secretion ; Exome Sequencing ; Mice, Inbred C57BL ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Obesity/genetics ; Gene Regulatory Networks ; Calcium Channels, N-Type/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Retinoid orphan receptor gamma t (rorγt) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis.
Autorzy:
Torres-Huerta A; Department of Microbiology & Immunology, Indiana University School of Medicine-South Bend, South Bend, IN, United States of America.
Ruley-Haase K; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Reed T; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Boger-May A; Department of Microbiology & Immunology, Indiana University School of Medicine-South Bend, South Bend, IN, United States of America.
Rubadeux D; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Mayer L; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Rajashekara AM; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Hiller M; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Frech M; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Roncagli C; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Pedersen C; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Camacho MC; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Hollmer L; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
English L; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Kane G; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
Boone DL; Department of Microbiology & Immunology, Indiana University School of Medicine-South Bend, South Bend, IN, United States of America.; Department of Biology, University of Notre Dame, South Bend, IN, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 21; Vol. 19 (3), pp. e0300892. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Colitis*
Inflammatory Bowel Diseases*/metabolism
Eosinophilia*/metabolism
Anti-Infective Agents*/metabolism
Mice ; Animals ; Immunity, Innate ; Lymphocytes/metabolism ; Nuclear Receptor Subfamily 1, Group F, Member 3/genetics ; Nuclear Receptor Subfamily 1, Group F, Member 3/metabolism ; Inflammation/metabolism ; Intestinal Mucosa/metabolism ; Retinoids ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Grain versus AIN: Common rodent diets differentially affect health outcomes in adult C57BL/6j mice.
Autorzy:
Schipper L; Danone Nutricia Research, Utrecht, The Netherlands.
Tims S; Danone Nutricia Research, Utrecht, The Netherlands.
Timmer E; Danone Nutricia Research, Utrecht, The Netherlands.
Lohr J; Danone Nutricia Research, Utrecht, The Netherlands.
Rakhshandehroo M; Danone Nutricia Research, Utrecht, The Netherlands.
Harvey L; Danone Nutricia Research, Utrecht, The Netherlands.
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Źródło:
PloS one [PLoS One] 2024 Mar 21; Vol. 19 (3), pp. e0293487. Date of Electronic Publication: 2024 Mar 21 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Rodentia*
Plant Breeding*
Pregnancy ; Mice ; Male ; Female ; Animals ; Mice, Inbred C57BL ; Reproducibility of Results ; Diet ; Outcome Assessment, Health Care
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Establishment of a hybrid model of atherosclerosis and acute colitis in ApoE-/- mice.
Autorzy:
Chen K; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Nanjing Drum Tower Hospital, Nanjing, P. R. China.
Zhang S; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Cui G; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zhang X; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Song Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.; Department of Ultrasound, Foshan First People's Hospital, Foshan, P. R. China.
Zheng J; Department of Traditional Chinese Medicine, Peking University Shenzhen Hospital, Shenzhen, P. R. China.
Chen Y; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
Zheng T; Shenzhen Key Laboratory for Drug Addiction and Medication Safety, Department of Ultrasound, Institute of Ultrasonic Medicine, Peking University Shenzhen Hospital, The Hong Kong University of Science and Technology Medical Center, Shenzhen- Peking University, Shenzhen, P. R. China.
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Źródło:
PloS one [PLoS One] 2024 Mar 18; Vol. 19 (3), pp. e0289820. Date of Electronic Publication: 2024 Mar 18 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Atherosclerosis*/diagnostic imaging
Atherosclerosis*/genetics
Plaque, Atherosclerotic*/diagnostic imaging
Plaque, Atherosclerotic*/complications
Colitis*/complications
Inflammatory Bowel Diseases*/complications
Humans ; Mice ; Animals ; Mice, Knockout ; Mice, Knockout, ApoE ; Diet, High-Fat/adverse effects ; Apolipoproteins E/genetics ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Transcriptome analysis reveals organ-specific effects of 2-deoxyglucose treatment in healthy mice.
Autorzy:
Wells AE; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Wilson JJ; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Heuer SE; The Jackson Laboratory, Bar Harbor, ME, United States of America.; Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States of America.
Sears JD; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Wei J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Shandong University, Jinan, Shandong, China.
Pandey R; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Costa MW; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Kaczorowski CC; The Jackson Laboratory, Bar Harbor, ME, United States of America.; Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States of America.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, United States of America.
Roopenian DC; The Jackson Laboratory, Bar Harbor, ME, United States of America.
Chang CH; The Jackson Laboratory, Bar Harbor, ME, United States of America.; Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States of America.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, United States of America.
Carter GW; The Jackson Laboratory, Bar Harbor, ME, United States of America.; Tufts University Graduate School of Biomedical Sciences, Boston, MA, United States of America.; Graduate School of Biomedical Sciences and Engineering, University of Maine, Orono, ME, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Mar 07; Vol. 19 (3), pp. e0299595. Date of Electronic Publication: 2024 Mar 07 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Deoxyglucose*/pharmacology
Deoxyglucose*/metabolism
Epilepsy*
Mice ; Animals ; Mice, Inbred C57BL ; Glucose/metabolism ; Gene Expression Profiling
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
High fat diet is associated with gut microbiota dysbiosis and decreased gut microbial derived metabolites related to metabolic health in young Göttingen Minipigs.
Autorzy:
Lützhøft DO; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Bækgård C; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Wimborne E; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Straarup EM; Novo Nordisk A/S, Maaloev, Denmark.
Pedersen KM; Novo Nordisk A/S, Maaloev, Denmark.
Swann JR; School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, United Kingdom.
Pedersen HD; Ellegaard Göttingen Minipigs A/S, Dalmose, Denmark.
Kristensen K; Novo Nordisk A/S, Maaloev, Denmark.
Morgills L; Scantox A/S, Lille Skensved, Denmark.
Nielsen DS; Department of Food Science, Faculty of Science, University of Copenhagen, Frederiksberg C, Denmark.
Hansen AK; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Bracken MK; Scantox A/S, Lille Skensved, Denmark.
Cirera S; Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Frederiksberg C, Denmark.
Christoffersen BØ; Novo Nordisk A/S, Maaloev, Denmark.
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Źródło:
PloS one [PLoS One] 2024 Mar 01; Vol. 19 (3), pp. e0298602. Date of Electronic Publication: 2024 Mar 01 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Metabolic Syndrome*/metabolism
Insulin Resistance*
Gastrointestinal Microbiome*
Swine ; Animals ; Male ; Female ; Humans ; Mice ; Swine, Miniature ; Diet, High-Fat/adverse effects ; Dysbiosis/metabolism ; Cholesterol ; Mice, Inbred C57BL
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The behavioral sensitivity of mice to acyclic, monocyclic, and bicyclic monoterpenes.
Autorzy:
Williams E; Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL, United States of America.
Pauley A; Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL, United States of America.
Dewan A; Department of Psychology, Program in Neuroscience, Florida State University, Tallahassee, FL, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Feb 23; Vol. 19 (2), pp. e0298448. Date of Electronic Publication: 2024 Feb 23 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Monoterpenes*/pharmacology
Acyclic Monoterpenes*
Cyclohexane Monoterpenes*
Mice ; Animals ; Limonene ; Mice, Inbred C57BL ; Bicyclic Monoterpenes
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Combined administration of anisodamine and neostigmine alleviated colitis by inducing autophagy and inhibiting inflammation.
Autorzy:
Liu M; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.; Air Force Hangzhou Special Service Recuperation Center Sanatorium Area 4, Nanjing, China.
Zhu D; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Yan H; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Dong Z; Department of General Surgery, Air Force Medical Center, PLA, Beijing, China.
Zhang J; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Kong N; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Zhang G; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Xu Q; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Han T; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
Ke P; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.; Air Force Hangzhou Special Service Recuperation Center Sanatorium Area 4, Nanjing, China.
Liu C; Department of Pharmacy, Second Military Medical University/Navy Military Medical University, Shanghai, China.
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Źródło:
PloS one [PLoS One] 2024 Feb 14; Vol. 19 (2), pp. e0291543. Date of Electronic Publication: 2024 Feb 14 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Neostigmine*/adverse effects
Colitis*/chemically induced
Colitis*/drug therapy
Colitis*/metabolism
Solanaceous Alkaloids*
Mice ; Animals ; Humans ; Tumor Necrosis Factor-alpha/metabolism ; alpha7 Nicotinic Acetylcholine Receptor/metabolism ; Interleukin-6/metabolism ; Caco-2 Cells ; Inflammation/drug therapy ; Inflammation/metabolism ; Autophagy ; Dextran Sulfate/toxicity ; Colon/metabolism ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Aromatase deficiency in transplanted bone marrow cells improves vertebral trabecular bone quantity, connectivity, and mineralization and decreases cortical porosity in murine bone marrow transplant recipients.
Autorzy:
Rubitschung K; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Sherwood A; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Kapadia R; Scanco USA Incorporated, Wayne, Pennsylvania, United States of America.
Xi Y; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Hajibeigi A; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.
Rubinow KB; Division of Metabolism, Endocrinology, and Nutrition, University of Washington Medicine Diabetes Institute, Seattle, Washington, United States of America.
Zerwekh JE; Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, UT Southwestern Medical Center, Dallas, Texas, United States of America.
Öz OK; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, Texas, United States of America.; Charles and Jane Pak Center for Mineral Metabolism and Clinical Research, UT Southwestern Medical Center, Dallas, Texas, United States of America.
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Źródło:
PloS one [PLoS One] 2024 Feb 05; Vol. 19 (2), pp. e0296390. Date of Electronic Publication: 2024 Feb 05 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Aromatase*/genetics
Aromatase*/metabolism
Bone Marrow Transplantation*
Gynecomastia*
Infertility, Male*
Metabolism, Inborn Errors*
46, XX Disorders of Sex Development*
Mice ; Animals ; Male ; Cancellous Bone/diagnostic imaging ; Cancellous Bone/metabolism ; Porosity ; Mice, Inbred C57BL ; Estrogens ; Estradiol ; Bone Marrow Cells/metabolism ; Spine/metabolism ; Mice, Knockout
SCR Disease Name:
Aromatase deficiency
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Time-restricted feeding has a limited effect on hepatic lipid accumulation, inflammation and fibrosis in a choline-deficient high-fat diet-induced murine NASH model.
Autorzy:
Sato T; Healthy Food Science Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.
Oishi K; Healthy Food Science Research Group, Cellular and Molecular Biotechnology Research Institute, National Institute of Advanced Industrial Science and Technology, Tsukuba, Japan.; Department of Computational Biology and Medical Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Kashiwa, Japan.; Department of Applied Biological Science, Graduate School of Science and Technology, Tokyo University of Science, Noda, Japan.
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Źródło:
PloS one [PLoS One] 2024 Jan 29; Vol. 19 (1), pp. e0296950. Date of Electronic Publication: 2024 Jan 29 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Non-alcoholic Fatty Liver Disease*/pathology
Choline Deficiency*/metabolism
Humans ; Animals ; Mice ; Choline/metabolism ; Diet, High-Fat/adverse effects ; Actins/metabolism ; Liver/metabolism ; Liver Cirrhosis/pathology ; Inflammation/pathology ; Fibrosis ; Obesity/complications ; Lipids/adverse effects ; Mice, Inbred C57BL ; Disease Models, Animal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Enhanced glucose utilization of skeletal muscle after 4 weeks of intermittent hypoxia in a mouse model of type 2 diabetes.
Autorzy:
Zhao Y; School of Social Sports and Health Sciences, Tianjin University of Sport, Tianjin, China.; School of Exercise and Health, Nanjing Sport Institute, Nanjing, Jiangsu, China.
Li C; School of Kinesiology, Shanghai University of Sport, Shanghai, China.
Zhou S; Faculty of Health, Southern Cross University, Lismore, Australia.
He Y; School of Social Sports and Health Sciences, Tianjin University of Sport, Tianjin, China.
Wang Y; Faculty of Health, Southern Cross University, Lismore, Australia.
Zhang Y; Faculty of Health, Southern Cross University, Lismore, Australia.
Wen L; School of Social Sports and Health Sciences, Tianjin University of Sport, Tianjin, China.; School of Exercise and Health, Nanjing Sport Institute, Nanjing, Jiangsu, China.
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Źródło:
PloS one [PLoS One] 2024 Jan 25; Vol. 19 (1), pp. e0296815. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*
Diabetes Mellitus, Experimental*
Insulin Resistance*/physiology
Humans ; Animals ; Mice ; Glucose ; Blood Glucose ; NAD ; Mice, Inbred C57BL ; Muscle, Skeletal ; Disease Models, Animal ; Hypoxia ; Lactates ; Pyruvates
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia.
Autorzy:
Mercado MAB; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Li Q; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Quick CM; Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Kim Y; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Palmer R; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Huang L; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
Li LX; Department of Microbiology and Immunology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 25; Vol. 20 (1), pp. e1011983. Date of Electronic Publication: 2024 Jan 25 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
CD4-Positive T-Lymphocytes*/cytology
CD4-Positive T-Lymphocytes*/immunology
Chlamydia Infections*/immunology
Chlamydia muridarum*/physiology
Basic Helix-Loop-Helix Transcription Factors*/metabolism
Homeodomain Proteins*/metabolism
Animals ; Female ; Mice ; Cell Differentiation ; Interleukin-10/metabolism ; Mice, Inbred C57BL ; Th1 Cells/metabolism
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Single cell RNA sequencing reveals endothelial cell killing and resolution pathways in experimental malaria-associated acute respiratory distress syndrome.
Autorzy:
Pollenus E; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Possemiers H; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Knoops S; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Prenen F; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Vandermosten L; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Thienpont C; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
Abdurahiman S; Laboratory of Mucosal Immunology, Translational Research in Gastro-Intestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Demeyer S; Laboratory of Molecular Biology of Leukemia, Department of Human Genetics, VIB-KU Leuven, Leuven, Belgium.
Cools J; Laboratory of Molecular Biology of Leukemia, Department of Human Genetics, VIB-KU Leuven, Leuven, Belgium.
Matteoli G; Laboratory of Mucosal Immunology, Translational Research in Gastro-Intestinal Disorders (TARGID), Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.
Vanoirbeek JAJ; Centre for Environment and Health, Department of Public Health and Primary Care, KU Leuven, Leuven, Belgium.
Vande Velde G; Biomedical MRI, Department of Imaging & Pathology, KU Leuven, Leuven, Belgium.
Van den Steen PE; Laboratory of Immunoparasitology, Department of Microbiology, Immunology & Transplantation, Rega Institute for Medical Research, KU Leuven, Leuven, Belgium.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 18; Vol. 20 (1), pp. e1011929. Date of Electronic Publication: 2024 Jan 18 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Antimalarials*/pharmacology
Antimalarials*/therapeutic use
Respiratory Distress Syndrome*/etiology
Respiratory Distress Syndrome*/metabolism
Malaria*/parasitology
Humans ; Animals ; Mice ; Endothelial Cells/metabolism ; X-Ray Microtomography/adverse effects ; Mice, Inbred C57BL ; Sequence Analysis, RNA ; Plasmodium berghei
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Locomotor activity as an effective measure of the severity of inflammatory arthritis in a mouse model.
Autorzy:
Doucet MR; Department of Chemistry and Biochemistry, New Brunswick Centre for Precision Medicine, Université de Moncton, Moncton, New Brunswick, Canada.
Laevski AM; Department of Chemistry and Biochemistry, New Brunswick Centre for Precision Medicine, Université de Moncton, Moncton, New Brunswick, Canada.
Doiron JA; Department of Chemistry and Biochemistry, New Brunswick Centre for Precision Medicine, Université de Moncton, Moncton, New Brunswick, Canada.
Boudreau LH; Department of Chemistry and Biochemistry, New Brunswick Centre for Precision Medicine, Université de Moncton, Moncton, New Brunswick, Canada.
Surette ME; Department of Chemistry and Biochemistry, New Brunswick Centre for Precision Medicine, Université de Moncton, Moncton, New Brunswick, Canada.
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Źródło:
PloS one [PLoS One] 2024 Jan 17; Vol. 19 (1), pp. e0291399. Date of Electronic Publication: 2024 Jan 17 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Arthritis*
Arthritis, Experimental*
Mice ; Animals ; Mice, Inbred C57BL ; Disease Models, Animal ; Locomotion ; Fish Oils/pharmacology
Czasopismo naukowe
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Tytuł:
Deficiency in astrocyte CCL2 production reduces neuroimmune control of Toxoplasma gondii infection.
Autorzy:
Orchanian SB; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, United States of America.; Institute for Immunology, University of California, Irvine, Irvine, California, United States of America.
Still K; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America.
Harris TH; Center for Brain Immunology and Glia, Department of Neuroscience, University of Virginia, Charlottesville, Virginia, United States of America.
Lodoen MB; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, United States of America.; Institute for Immunology, University of California, Irvine, Irvine, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 11; Vol. 20 (1), pp. e1011710. Date of Electronic Publication: 2024 Jan 11 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Toxoplasma*/metabolism
Toxoplasmosis*/metabolism
Animals ; Humans ; Mice ; Astrocytes/metabolism ; Brain/metabolism ; Chemokine CCL2/metabolism ; Mice, Inbred C57BL ; Mice, Knockout
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Ketogenic diet preserves muscle mass and strength in a mouse model of type 2 diabetes.
Autorzy:
Park SB; Department of Food and Nutrition, Seoul Women's University, Seoul, Republic of Korea.
Yang SJ; Department of Food and Nutrition, Seoul Women's University, Seoul, Republic of Korea.
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Źródło:
PloS one [PLoS One] 2024 Jan 10; Vol. 19 (1), pp. e0296651. Date of Electronic Publication: 2024 Jan 10 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Diabetes Mellitus, Type 2*
Diet, Ketogenic*
Diabetes Mellitus, Experimental*
Animals ; Mice ; Mice, Inbred C57BL ; NLR Family, Pyrin Domain-Containing 3 Protein ; Inflammasomes ; Disease Models, Animal ; Muscle Fibers, Skeletal
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
The pathogenesis of experimental Emergomycosis in mice.
Autorzy:
Höft MA; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Duvenage L; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Salie S; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Keeton R; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.
Botha A; Department of Microbiology, Stellenbosch University, Stellenbosch, South Africa.
Schwartz IS; Division of Infectious Diseases, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, United States of America.
Govender NP; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; National Institute for Communicable Diseases, Division of the National Health Laboratory Service, Johannesburg, South Africa; School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.; Medical Research Council Centre for Medical Mycology at the University of Exeter, Geoffrey Pope Building Stocker Road, Exeter, United Kingdom.
Brown GD; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Medical Research Council Centre for Medical Mycology at the University of Exeter, Geoffrey Pope Building Stocker Road, Exeter, United Kingdom.
Hoving JC; CMM AFRICA Medical Mycology Research Unit, Institute of Infectious Diseases and Molecular Medicine (IDM), University of Cape Town, Cape Town, South Africa.; Division of Immunology, Department of Pathology, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa.; Medical Research Council Centre for Medical Mycology at the University of Exeter, Geoffrey Pope Building Stocker Road, Exeter, United Kingdom.
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Źródło:
PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2024 Jan 10; Vol. 18 (1), pp. e0011850. Date of Electronic Publication: 2024 Jan 10 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Mycoses*/microbiology
HIV Infections*
Humans ; Animals ; Mice ; Disease Models, Animal ; Mice, Inbred C57BL
SCR Disease Name:
emmonsiosis
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Elimination of Chlamydia muridarum from the female reproductive tract is IL-12p40 dependent, but independent of Th1 and Th2 cells.
Autorzy:
Rixon JA; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
Fong KD; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
Morris C; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
Nguyen AT; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
Depew CE; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
McSorley SJ; Department of Anatomy, Physiology and Cell Biology, School of Veterinary Medicine, University of California Davis, Davis, California, United States of America.
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Źródło:
PLoS pathogens [PLoS Pathog] 2024 Jan 02; Vol. 20 (1), pp. e1011914. Date of Electronic Publication: 2024 Jan 02 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Chlamydia Infections*/genetics
Chlamydia Infections*/microbiology
Chlamydia muridarum*
Animals ; Female ; Mice ; CD4-Positive T-Lymphocytes ; Interleukin-12 Subunit p40 ; Mice, Inbred C57BL ; Th1 Cells ; Th17 Cells ; Th2 Cells
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
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