Temat: "Mice, Knockout" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: [Generation and validation of inducible osteoblast-specific Stat3 knockout mice].
Autorzy :: Gong XY; Shanghai Ninth People's Hospital, College of Stomatology, Shanghai Jiao Tong University School of Medicine; National Clinical Research Center for Oral Diseases; Shanghai Key Laboratory of Stomatology and Shanghai Research Institute of Stomatology. Shanghai 200011, China. E-mail:.
Huang XR
Zhou SR
Yang YL
Xu HY
Jin AT
Dai QG
Jiang LY; Pokaż więcej
Źródło :: Shanghai kou qiang yi xue = Shanghai journal of stomatology [Shanghai Kou Qiang Yi Xue] 2020 Aug; Vol. 29 (4), pp. 337-342.
Typ publikacji :: Journal Article
MeSH Terms :: Mice, Knockout*
Osteoblasts*
STAT3 Transcription Factor*
Tooth Movement Techniques*
Animals ; Gene Knockout Techniques ; Mice ; RNA, Messenger
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: TIEG1 is upregulated in Lrp5/6-mediated valve osteogenesis.
Autorzy :: Rajamannan NM; Department of Cardiology, Most Sacred Heart of Jesus Cardiology and Valvular Institute, Sheboygan, Wisconsin.; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota.; Pokaż więcej
Źródło :: Journal of cellular biochemistry [J Cell Biochem] 2019 Mar; Vol. 120 (3), pp. 3362-3366. Date of Electronic Publication: 2018 Sep 23.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: Osteogenesis*
Aortic Valve Stenosis/*pathology
Calcinosis/*pathology
DNA-Binding Proteins/*physiology
Low Density Lipoprotein Receptor-Related Protein-5/*physiology
Low Density Lipoprotein Receptor-Related Protein-6/*metabolism
Mice, Knockout, ApoE/*physiology
Transcription Factors/*physiology
Animals ; Aortic Valve Stenosis/genetics ; Aortic Valve Stenosis/metabolism ; Calcinosis/genetics ; Calcinosis/metabolism ; Cell Differentiation ; Core Binding Factor Alpha 1 Subunit/genetics ; Core Binding Factor Alpha 1 Subunit/metabolism ; Female ; Hypercholesterolemia/genetics ; Hypercholesterolemia/metabolism ; Hypercholesterolemia/pathology ; Low Density Lipoprotein Receptor-Related Protein-6/genetics ; Male ; Mice ; Mice, Knockout ; Osteoblasts/metabolism ; Osteoblasts/pathology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 3 3.

Tytuł :: Ginkgolide C attenuates lipopolysaccharide‑induced acute lung injury by inhibiting inflammation via regulating the CD40/NF‑κB signaling pathway.
Autorzy :: Zhang R; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Guo N; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Yan G; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Wang Q; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Gao T; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Zhang B; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.
Hou N; Department of Pharmacy, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, P.R. China.; Pokaż więcej
Źródło :: International journal of molecular medicine [Int J Mol Med] 2021 Apr; Vol. 47 (4). Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :: Journal Article
MeSH Terms :: Acute Lung Injury/*drug therapy
CD40 Antigens/*antagonists & inhibitors
Ginkgolides/*pharmacology
I-kappa B Kinase/*metabolism
Lactones/*pharmacology
Transcription Factor RelA/*metabolism
Acute Lung Injury/pathology ; Animals ; CD40 Antigens/genetics ; CD40 Antigens/metabolism ; Cells, Cultured ; Cytokines/blood ; Hydroxyproline/metabolism ; Inflammation/drug therapy ; Lipopolysaccharides/toxicity ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Neutrophil Infiltration/drug effects ; Neutrophils/immunology ; Peroxidase/metabolism ; Signal Transduction/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 4 4.

Tytuł :: Iron overload in aging Bmp6 mice induces exocrine pancreatic injury and fibrosis due to acinar cell loss.
Autorzy :: Pauk M; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Kufner V; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Rumenovic V; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Dumic-Cule I; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Farkas V; Molecular Biology Department, Rudjer Boskovic Institute, HR‑10000 Zagreb, Croatia.
Milosevic M; Andrija Stampar School of Public Health, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Bordukalo-Niksic T; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.
Vukicevic S; Laboratory for Mineralized Tissues, Center for Translational and Clinical Research, School of Medicine, University of Zagreb, HR‑10000 Zagreb, Croatia.; Pokaż więcej
Źródło :: International journal of molecular medicine [Int J Mol Med] 2021 Apr; Vol. 47 (4), pp. 1-8. Date of Electronic Publication: 2021 Mar 02.
Typ publikacji :: Journal Article
MeSH Terms :: Acinar Cells/*pathology
Bone Morphogenetic Protein 6/*genetics
Diabetes Mellitus/*pathology
Hemochromatosis/*pathology
Iron Overload/*pathology
Animals ; Blood Glucose/analysis ; Disease Models, Animal ; Fibrosis/pathology ; Fluorodeoxyglucose F18/pharmacokinetics ; Glucose/metabolism ; Iron/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Pancreas/injuries ; Pancreas/pathology ; Positron-Emission Tomography
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 5 5.

Tytuł :: miRNA-22 deletion limits white adipose expansion and activates brown fat to attenuate high-fat diet-induced fat mass accumulation.
Autorzy :: Lima VM; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Liu J; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Brandão BB; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Lino CA; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Balbino Silva CS; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Ribeiro MAC; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Oliveira TE; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Real CC; Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
de Paula Faria D; Department of Radiology and Oncology, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Sao Paulo, Brazil.
Cederquist C; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Huang ZP; Center for Translational Medicine, The First Affiliated Hospital, NHC Key Laboratory of Assisted Circulation, Sun Yat-sen University, Guangzhou, China.
Hu X; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Barreto-Chaves ML; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Ferreira JCB; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil; Department of Chemical and Systems Biology, Stanford University School of Medicine, California, USA.
Festuccia WT; Department of Physiology and Biophysics, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil.
Mori MA; Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, Brazil.
Kahn CR; Joslin Diabetes Center, Harvard Medical School, Boston, MA, USA.
Wang DZ; Department of Cardiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
Diniz GP; Department of Anatomy, Institute of Biomedical Sciences, University of Sao Paulo, Sao Paulo, Brazil. Electronic address: .; Pokaż więcej
Źródło :: Metabolism: clinical and experimental [Metabolism] 2021 Apr; Vol. 117, pp. 154723. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Adipose Tissue, Beige/*metabolism
Adipose Tissue, Brown/*metabolism
Adipose Tissue, White/*metabolism
Diet, High-Fat/*adverse effects
MicroRNAs/*genetics
Adipogenesis/genetics ; Animals ; Cell Differentiation/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitochondria/metabolism ; Mitochondrial Diseases/genetics ; Mitochondrial Diseases/metabolism ; Obesity/genetics ; Obesity/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: NAFLD exacerbates cholangitis and promotes cholangiocellular carcinoma in mice.
Autorzy :: Maeda S; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Hikiba Y; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Fujiwara H; Division of Gastroenterology, Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan.
Ikenoue T; Division of Clinical Genome Research, Advanced Clinical Research Center, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
Sue S; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Sugimori M; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Matsubayashi M; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Kaneko H; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Irie K; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Sasaki T; Department of Gastroenterology, Yokohama City University Graduate School of Medicine, Yokohama, Japan.
Chuma M; Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.; Pokaż więcej
Źródło :: Cancer science [Cancer Sci] 2021 Apr; Vol. 112 (4), pp. 1471-1480. Date of Electronic Publication: 2021 Feb 14.
Typ publikacji :: Journal Article
MeSH Terms :: Bile Duct Neoplasms/*pathology
Cholangiocarcinoma/*pathology
Cholangitis/*pathology
Non-alcoholic Fatty Liver Disease/*pathology
Animals ; Antigens, CD/metabolism ; Bile Duct Neoplasms/metabolism ; Carcinoma, Hepatocellular/metabolism ; Carcinoma, Hepatocellular/pathology ; Cholangiocarcinoma/metabolism ; Cholangitis/metabolism ; Diet, High-Fat/adverse effects ; Disease Models, Animal ; Inflammation/metabolism ; Inflammation/pathology ; Liver Neoplasms/metabolism ; Liver Neoplasms/pathology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Non-alcoholic Fatty Liver Disease/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 7 7.

Tytuł :: A Potential Role for SerpinA3N in Acetaminophen-Induced Hepatotoxicity.
Autorzy :: Tran M; Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (M.T., J.W., D.-J.S.) and Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut (L.W.) .
Wu J; Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (M.T., J.W., D.-J.S.) and Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut (L.W.).
Wang L; Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (M.T., J.W., D.-J.S.) and Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut (L.W.).
Shin DJ; Department of Physiology and Neurobiology, University of Connecticut, Storrs, Connecticut (M.T., J.W., D.-J.S.) and Department of Internal Medicine, Section of Digestive Diseases, Yale University, New Haven, Connecticut (L.W.) .; Pokaż więcej
Źródło :: Molecular pharmacology [Mol Pharmacol] 2021 Apr; Vol. 99 (4), pp. 277-285. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :: Acetaminophen/*toxicity
Acute-Phase Proteins/*deficiency
Analgesics, Non-Narcotic/*toxicity
Chemical and Drug Induced Liver Injury/*metabolism
Serpins/*deficiency
Acute-Phase Proteins/genetics ; Animals ; Chemical and Drug Induced Liver Injury/genetics ; Male ; Mice ; Mice, 129 Strain ; Mice, Inbred C57BL ; Mice, Knockout ; Serpins/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: A Novel Syngeneic Immunocompetent Mouse Model of Head and Neck Cancer Pain Independent of Interleukin-1 Signaling.
Autorzy :: Heussner MJ; From the Department of Physiology and.; College of Osteopathic Medicine, Michigan State University, East Lansing, Michigan.
Folger JK; From the Department of Physiology and.
Dias C; Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Massri N; From the Department of Physiology and.
Dahdah A; Department of Microbiology & Molecular Genetics, Michigan State University, East Lansing, Michigan.
Vermeer PD; Cancer Biology and Immunotherapies Group, Sanford Research, Sioux Falls, South Dakota.
Laumet G; From the Department of Physiology and.; Department of Symptom Research, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Pokaż więcej
Źródło :: Anesthesia and analgesia [Anesth Analg] 2021 Apr 01; Vol. 132 (4), pp. 1156-1163.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Cancer Pain/*etiology
Interleukin-1beta/*metabolism
Oropharyngeal Neoplasms/*complications
Spinal Cord/*metabolism
Squamous Cell Carcinoma of Head and Neck/*complications
Animals ; Behavior, Animal ; Cancer Pain/metabolism ; Cancer Pain/physiopathology ; Cell Line, Tumor ; Interleukin 1 Receptor Antagonist Protein/genetics ; Interleukin 1 Receptor Antagonist Protein/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Oropharyngeal Neoplasms/metabolism ; Oropharyngeal Neoplasms/virology ; Pain Threshold ; Papillomaviridae/pathogenicity ; Signal Transduction ; Spinal Cord/physiopathology ; Squamous Cell Carcinoma of Head and Neck/metabolism ; Squamous Cell Carcinoma of Head and Neck/virology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: Effects of clonidine on progressive ratio schedule performance in Fmr1 knockout mice.
Autorzy :: Wrenn CC; College of Pharmacy and Health Sciences, Drake University, 2507 University Ave, Des Moines, IA, 50311, USA. .
French E; Psychology Department, Central Michigan University, East Campus Dr, Mount Pleasant, MI, 48858, USA.
Baker D; Psychology Department, Drake University, 2507 University Ave, Des Moines, IA, 50311, USA.
McCallian R; Psychology Department, Drake University, 2507 University Ave, Des Moines, IA, 50311, USA.
Kirk R; Psychology Department, Drake University, 2507 University Ave, Des Moines, IA, 50311, USA.
Reilly MP; Psychology Department, Central Michigan University, East Campus Dr, Mount Pleasant, MI, 48858, USA.
Valdovinos MG; Psychology Department, Drake University, 2507 University Ave, Des Moines, IA, 50311, USA.; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2021 Apr; Vol. 238 (4), pp. 1133-1140. Date of Electronic Publication: 2021 Jan 15.
Typ publikacji :: Journal Article
MeSH Terms :: Reinforcement Schedule*
Adrenergic alpha-2 Receptor Agonists/*pharmacology
Clonidine/*pharmacology
Conditioning, Operant/*drug effects
Fragile X Mental Retardation Protein/*genetics
Animals ; Fragile X Syndrome/psychology ; Genotype ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Motivation/drug effects ; Reward
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: A missense allele of PEX5 is responsible for the defective import of PTS2 cargo proteins into peroxisomes.
Autorzy :: Ali M; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.
Khan SY; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.
Rodrigues TA; Instituto de Biologia Celular E Molecular, Universidade Do Porto, Porto, Portugal.; Instituto de Investigação E Inovação Em Saúde, Universidade Do Porto, Porto, Portugal.; Instituto de Ciências Biomédicas Abel Salazar, Universidade Do Porto, Porto, Portugal.
Francisco T; Instituto de Biologia Celular E Molecular, Universidade Do Porto, Porto, Portugal.; Instituto de Investigação E Inovação Em Saúde, Universidade Do Porto, Porto, Portugal.; Instituto de Ciências Biomédicas Abel Salazar, Universidade Do Porto, Porto, Portugal.
Jiao X; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Qi H; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Kabir F; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Irum B; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Rauf B; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA.; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Khan AA; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Mehmood A; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Naeem MA; National Centre of Excellence in Molecular Biology, University of the Punjab, Lahore, Pakistan.
Assir MZ; Allama Iqbal Medical College, University of Health Sciences, Lahore, Pakistan.
Ali MH; Allama Iqbal Medical College, University of Health Sciences, Lahore, Pakistan.
Shahzad M; Jinnah Burn and Reconstructive Surgery Center, Jinnah Hospital, Lahore, Pakistan.; Department of Molecular Biology, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.
Abu-Amero KK; Department of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois, Chicago, IL, USA.
Akram SJ; Akram Medical Complex, Lahore, Pakistan.
Akram J; University of Health Sciences, Lahore, Pakistan.
Riazuddin S; Allama Iqbal Medical College, University of Health Sciences, Lahore, Pakistan.; Jinnah Burn and Reconstructive Surgery Center, Jinnah Hospital, Lahore, Pakistan.; Department of Molecular Biology, Shaheed Zulfiqar Ali Bhutto Medical University, Islamabad, Pakistan.
Riazuddin S; Department of Otorhinolaryngology - Head and Neck Surgery, University of Maryland School Medicine, Baltimore, MD, USA.
Robinson ML; Department of Biology, Miami University, Oxford, OH, USA.
Baes M; Department of Pharmaceutical and Pharmacological Sciences, Lab of Cell Metabolism, University of Leuven, Leuven, Belgium.
Azevedo JE; Instituto de Biologia Celular E Molecular, Universidade Do Porto, Porto, Portugal.; Instituto de Investigação E Inovação Em Saúde, Universidade Do Porto, Porto, Portugal.; Instituto de Ciências Biomédicas Abel Salazar, Universidade Do Porto, Porto, Portugal.
Hejtmancik JF; Ophthalmic Genetics and Visual Function Branch, National Eye Institute, National Institutes of Health, Bethesda, MD, USA.
Riazuddin SA; The Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore MD, USA. .; Pokaż więcej
Źródło :: Human genetics [Hum Genet] 2021 Apr; Vol. 140 (4), pp. 649-666. Date of Electronic Publication: 2021 Jan 02.
Typ publikacji :: Journal Article
MeSH Terms :: Mutation, Missense*
Peroxisomal Targeting Signals*
Cataract/*genetics
Peroxisome-Targeting Signal 1 Receptor/*genetics
Peroxisomes/*metabolism
ATP-Binding Cassette Transporters/metabolism ; Animals ; Biological Transport, Active ; Cataract/congenital ; Cataract/metabolism ; Chromosomes, Human, Pair 12 ; Consanguinity ; Female ; Genetic Linkage ; Humans ; Lens, Crystalline/metabolism ; Male ; Mice ; Mice, Knockout ; Peroxisome-Targeting Signal 1 Receptor/metabolism ; Sequestosome-1 Protein/metabolism ; Whole Exome Sequencing
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 11 11.

Tytuł :: Disruption of Sinonasal Epithelial Nrf2 Enhances Susceptibility to Rhinosinusitis in a Mouse Model.
Autorzy :: Ramanathan M Jr; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, U.S.A.
Tharakan A; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, U.S.A.
Sidhaye VK; Division of Pulmonary Medicine, Department of Internal Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland, U.S.A.; Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, U.S.A.
Lane AP; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, U.S.A.
Biswal S; Department of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, U.S.A.
London NR Jr; Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins Medicine, Baltimore, Maryland, U.S.A.; Pokaż więcej
Źródło :: The Laryngoscope [Laryngoscope] 2021 Apr; Vol. 131 (4), pp. 713-719. Date of Electronic Publication: 2020 Jul 06.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :: NF-E2-Related Factor 2/*metabolism
Rhinitis/*metabolism
Sinusitis/*metabolism
Animals ; Disease Models, Animal ; Disease Susceptibility ; Inflammation ; Mice ; Mice, Knockout ; Oxidative Stress ; Papain
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 12 12.

Tytuł :: Depletion of serotonin relieves concanavalin A-induced liver fibrosis in mice by inhibiting inflammation, oxidative stress, and TGF-β1/Smads signaling pathway.
Autorzy :: Pang Q; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China; Department of Hepatobiliary Surgery, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061 Shaanxi Province, China.
Jin H; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China.
Wang Y; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China.
Dai M; Clinical Medical College of Bengbu Medical College, Bengbu, 233000 Anhui Province, China.
Liu S; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China.
Tan Y; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China. Electronic address: .
Liu H; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China. Electronic address: .
Lu Z; Department of Hepatobiliary Surgery, First Affiliated Hospital of Bengbu Medical College, Bengbu, 233000 Anhui Province, China. Electronic address: .; Pokaż więcej
Źródło :: Toxicology letters [Toxicol Lett] 2021 Apr 01; Vol. 340, pp. 123-132. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :: Journal Article
MeSH Terms :: Concanavalin A/*pharmacology
Inflammation/*chemically induced
Liver Cirrhosis/*chemically induced
Oxidative Stress/*drug effects
Serotonin/*pharmacology
Transforming Growth Factor beta1/*metabolism
Animals ; Concanavalin A/administration & dosage ; Humans ; Inflammation/prevention & control ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitogens/toxicity ; Signal Transduction ; Smad Proteins/genetics ; Smad Proteins/metabolism ; Transforming Growth Factor beta1/genetics ; Tryptophan Hydroxylase/genetics ; Tryptophan Hydroxylase/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: Conditional Ror1 knockout reveals crucial involvement in lung adenocarcinoma development and identifies novel HIF-1α regulator.
Autorzy :: Isomura H; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Division of Molecular Diagnostics, Aichi Cancer Center Research Institute, Nagoya, Japan.
Taguchi A; Division of Molecular Diagnostics, Aichi Cancer Center Research Institute, Nagoya, Japan.; Division of Advanced Cancer Diagnostics, Department of Cancer Diagnostics and Therapeutics, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kajino T; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Division of Molecular Diagnostics, Aichi Cancer Center Research Institute, Nagoya, Japan.
Asai N; Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Pathology, Fujita Health University School of Medicine, Toyoake, Japan.
Nakatochi M; Public Health Informatics Unit, Department of Integrated Health Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Kato S; Department of Pathology and Molecular Diagnostics, Aichi Cancer Center Hospital, Nagoya, Japan.
Suzuki K; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Yanagisawa K; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Suzuki M; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Molecular Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Fujishita T; Division of Pathophysiology, Aichi Cancer Center Research Institute, Nagoya, Japan.
Yamaguchi T; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Cancer Biology, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan.; Center for Metabolic Regulation of Healthy Aging, Kumamoto University, Kumamoto, Japan.
Takahashi M; Department of Pathology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Takahashi T; Division of Molecular Carcinogenesis, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Aichi Cancer Center, Nagoya, Japan.; Pokaż więcej
Źródło :: Cancer science [Cancer Sci] 2021 Apr; Vol. 112 (4), pp. 1614-1623. Date of Electronic Publication: 2021 Feb 19.
Typ publikacji :: Journal Article
MeSH Terms :: Adenocarcinoma of Lung/*genetics
Hypoxia-Inducible Factor 1, alpha Subunit/*genetics
Lung Neoplasms/*genetics
Receptor Tyrosine Kinase-like Orphan Receptors/*genetics
Adenocarcinoma of Lung/pathology ; Animals ; Cell Line, Tumor ; Down-Regulation/genetics ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Hypoxia/genetics ; Lung Neoplasms/pathology ; Mice ; Mice, Inbred BALB C ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Oncogenes/genetics ; Signal Transduction/genetics ; Thyroid Nuclear Factor 1/genetics ; Tumor Microenvironment/genetics
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Knockout of NRAGE promotes autophagy-related gene expression and the periodontitis process in mice.
Autorzy :: Liu H; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhang X; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yang Q; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhu X; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Chen F; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Yue J; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Zhou R; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Xu Y; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Qi S; Department of Stomatology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.; Pokaż więcej
Źródło :: Oral diseases [Oral Dis] 2021 Apr; Vol. 27 (3), pp. 589-599. Date of Electronic Publication: 2020 Aug 20.
Typ publikacji :: Journal Article
MeSH Terms :: Alveolar Bone Loss*/diagnostic imaging
Alveolar Bone Loss*/genetics
Periodontitis*/genetics
Animals ; Autophagy ; Disease Models, Animal ; Gene Expression ; Mice ; Mice, Knockout ; Osteoclasts ; X-Ray Microtomography
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: The neuroprotective effect of oxytocin on vincristine-induced neurotoxicity in mice.
Autorzy :: Zhu J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China.
Li Y; Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China.
Liang J; Qilu Hospital, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China.
Li J; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China.
Huang K; Department of Oncology, Shandong University Qilu Hospital, Jinan, Shandong, PR China.
Li J; Department of Pathology, Zibo Central Hospital, Zibo, Shandong, PR China.
Liu C; Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Cheeloo College of Medicine, Shandong University, Jinan, Shandong, PR China. Electronic address: .; Pokaż więcej
Źródło :: Toxicology letters [Toxicol Lett] 2021 Apr 01; Vol. 340, pp. 67-76. Date of Electronic Publication: 2021 Jan 08.
Typ publikacji :: Journal Article
MeSH Terms :: Oxytocics/*toxicity
Oxytocin/*therapeutic use
Peripheral Nervous System Diseases/*chemically induced
Peripheral Nervous System Diseases/*drug therapy
Vincristine/*toxicity
Animals ; Antineoplastic Agents, Phytogenic/toxicity ; Hyperalgesia/chemically induced ; Mice ; Mice, Knockout ; Neurotoxicity Syndromes/drug therapy ; Receptors, Oxytocin/antagonists & inhibitors ; Sciatic Nerve/drug effects ; Vasotocin/analogs & derivatives ; Vasotocin/toxicity
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: Cannabinoid type 1 receptors in A2a neurons contribute to cocaine-environment association.
Autorzy :: Turner BD; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.
Smith NK; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.
Manz KM; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.; Medical Scientist Training Program, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Chang BT; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.
Delpire E; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA.
Grueter CA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.
Grueter BA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA. .; Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA. .; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, TN, 37232, USA. .; Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN, 37232, USA. .; Anesthesiology Research Division, Vanderbilt University School of Medicine, 2213 Garland Avenue, P435H MRB IV, Nashville, TN, 37232-0413, USA. .; Pokaż więcej
Źródło :: Psychopharmacology [Psychopharmacology (Berl)] 2021 Apr; Vol. 238 (4), pp. 1121-1131. Date of Electronic Publication: 2021 Jan 16.
Typ publikacji :: Journal Article
MeSH Terms :: Environment*
Cocaine-Related Disorders/*psychology
Neurons/*drug effects
Receptor, Adenosine A2A/*drug effects
Receptor, Cannabinoid, CB1/*drug effects
Receptor, Cannabinoid, CB1/*metabolism
Animals ; Conditioning, Operant/drug effects ; Corpus Striatum/drug effects ; Male ; Mice ; Mice, Knockout ; Motor Activity/drug effects ; Receptor, Adenosine A2A/genetics ; Receptor, Cannabinoid, CB1/genetics ; Reward
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: GPR10 gene deletion in mice increases basal neuronal activity, disturbs insulin sensitivity and alters lipid homeostasis.
Autorzy :: Pražienková V; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Funda J; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Pirník Z; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic; Biomedical Research Center SAS of the Slovak Academy of Sciences, 845 05 Bratislava, Slovak Republic; Institute of Physiology, Faculty of Medicine, Comenius University in Bratislava, 813 72 Bratislava, Slovak Republic.
Karnošová A; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Hrubá L; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Kořínková L; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Neprašová B; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Janovská P; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Benzce M; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Kadlecová M; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Blahoš J; Institute of Molecular Genetics of the Czech Academy of Sciences, 14220 Prague, Czech Republic.
Kopecký J; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Železná B; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic.
Kuneš J; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Bardová K; Institute of Physiology of the Czech Academy of Sciences, 14200 Prague, Czech Republic.
Maletínská L; Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, 16610 Prague, Czech Republic. Electronic address: .; Pokaż więcej
Źródło :: Gene [Gene] 2021 Mar 30; Vol. 774, pp. 145427. Date of Electronic Publication: 2021 Jan 12.
Typ publikacji :: Journal Article
MeSH Terms :: Homeostasis/*genetics
Insulin Resistance/*genetics
Lipid Metabolism/*genetics
Receptors, G-Protein-Coupled/*genetics
Animals ; Energy Metabolism/genetics ; Female ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Obesity/genetics ; Prolactin-Releasing Hormone/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Host-derived lipids orchestrate pulmonary γδ T cell response to provide early protection against influenza virus infection.
Autorzy :: Wang X; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China. .; Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China. .
Lin X; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.
Zheng Z; Chongqing International Institute for Immunology, Chongqing, China.
Lu B; Department of Respiratory Medicine and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Wang J; Department of Respiratory Medicine and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Tan AH; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore.
Zhao M; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing, China.
Loh JT; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Ng SW; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore.
Chen Q; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.
Xiao F; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.
Huang E; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.
Ko KH; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.
Huang Z; Department of Pathogen Biology and Immunology, Shenzhen University School of Medicine, Shenzhen, China.
Li J; Chongqing International Institute for Immunology, Chongqing, China.
Kok KH; Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China.
Lu G; Department of Respiratory Medicine and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Liu X; National Protein Science Facility, Tsinghua University, Beijing, China.
Lam KP; Bioprocessing Technology Institute, Agency for Science, Technology and Research, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore.
Liu W; Ministry of Education Key Laboratory of Protein Sciences, Center for Life Sciences, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Institute for Immunology, School of Life Sciences, Tsinghua University, Beijing, China.
Zhang Y; Department of Respiratory Medicine and Guangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, China.
Yuen KY; Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China.
Mak TW; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China.; The Campbell Family Institute for Breast Cancer Research at Princess Margaret Cancer Centre, Ontario Cancer Institute, University Health Network, Toronto, ON, Canada.
Lu L; Department of Pathology and Shenzhen Institute of Research and Innovation, The University of Hong Kong, Hong Kong, China. .; Chongqing International Institute for Immunology, Chongqing, China. .; Pokaż więcej
Źródło :: Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1914. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Influenza A Virus, H1N1 Subtype/*immunology
Influenza, Human/*immunology
Lipids/*immunology
Orthomyxoviridae Infections/*immunology
Receptors, Antigen, T-Cell, gamma-delta/*immunology
Animals ; Antigens, CD1d/immunology ; Antigens, CD1d/metabolism ; Female ; Host-Pathogen Interactions/immunology ; Humans ; Immunity, Innate/immunology ; Influenza A Virus, H1N1 Subtype/physiology ; Influenza, Human/metabolism ; Influenza, Human/virology ; Interferon Regulatory Factors/immunology ; Interferon Regulatory Factors/metabolism ; Interleukin-17/immunology ; Interleukin-17/metabolism ; Lung/immunology ; Lung/metabolism ; Lung/virology ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Orthomyxoviridae Infections/metabolism ; Orthomyxoviridae Infections/virology ; Receptors, Antigen, T-Cell, gamma-delta/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer's disease.
Autorzy :: Zheng K; Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hu F; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Zhou Y; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Zhang J; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Zheng J; Department of Geriatrics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Lai C; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Xiong W; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Cui K; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China.
Hu YZ; Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatric Disease, Institute of Geriatrics, Chinese PLA General Hospital and Chinese PLA Medical Academy, Beijing, P. R. China.
Han ZT; Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatric Disease, Institute of Geriatrics, Chinese PLA General Hospital and Chinese PLA Medical Academy, Beijing, P. R. China.
Zhang HH; Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatric Disease, Institute of Geriatrics, Chinese PLA General Hospital and Chinese PLA Medical Academy, Beijing, P. R. China.
Chen JG; The Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, P. R. China.
Man HY; Department of Biology, Boston University, Boston, MA, USA.
Liu D; The Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, P. R. China.
Lu Y; The Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, P. R. China. .
Zhu LQ; Department of Pathophysiology, Key Lab of Neurological Disorder of Education Ministry, School of Basic Medicine, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, P. R. China. .; The Institute of Brain Research, Collaborative Innovation Center for Brain Science, Huazhong University of Science and Technology, Wuhan, P. R. China. .; Pokaż więcej
Źródło :: Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1903. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Alzheimer Disease/*genetics
Cytoskeletal Proteins/*genetics
Memory Disorders/*genetics
MicroRNAs/*genetics
Synapses/*metabolism
rho-Associated Kinases/*genetics
Alzheimer Disease/metabolism ; Alzheimer Disease/physiopathology ; Animals ; Cells, Cultured ; Cytoskeletal Proteins/metabolism ; Disease Models, Animal ; Hippocampus/cytology ; Hippocampus/metabolism ; Male ; Maze Learning/physiology ; Memory Disorders/metabolism ; Memory Disorders/physiopathology ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Neurons/metabolism ; Neurons/physiology ; Phosphorylation ; Signal Transduction/genetics ; Signal Transduction/physiology ; Synapses/physiology ; rho-Associated Kinases/metabolism ; tau Proteins/genetics ; tau Proteins/metabolism
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Overcoming the inhibitory microenvironment surrounding oligodendrocyte progenitor cells following experimental demyelination.
Autorzy :: Saraswat D; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Shayya HJ; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Polanco JJ; Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Tripathi A; Department of Neuroscience, Lerner Research Institute, Cleveland, OH, USA.
Welliver RR; Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Pol SU; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Seidman RA; Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
Broome JE; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
O'Bara MA; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA.
van Kuppervelt TH; Department of Biochemistry, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, The Netherlands.
Phillips JJ; Department of Neurological Surgery, University of California, San Francisco, CA, USA.
Dutta R; Department of Neuroscience, Lerner Research Institute, Cleveland, OH, USA.
Sim FJ; Department of Pharmacology and Toxicology, Jacob's School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. .; Neuroscience Program, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, NY, USA. .; Pokaż więcej
Źródło :: Nature communications [Nat Commun] 2021 Mar 26; Vol. 12 (1), pp. 1923. Date of Electronic Publication: 2021 Mar 26.
Typ publikacji :: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :: Cell Differentiation/*genetics
Cellular Microenvironment/*genetics
Demyelinating Diseases/*genetics
Gene Expression Profiling/*methods
Oligodendrocyte Precursor Cells/*metabolism
Remyelination/*genetics
Animals ; Axons/metabolism ; Cells, Cultured ; Demyelinating Diseases/metabolism ; Female ; Humans ; Mice ; Mice, Inbred BALB C ; Mice, Knockout ; Mice, Transgenic ; Multiple Sclerosis/genetics ; Multiple Sclerosis/metabolism ; Oligodendrocyte Precursor Cells/cytology ; Sulfatases/genetics ; Sulfatases/metabolism ; Sulfotransferases/genetics ; Sulfotransferases/metabolism
: Czasopismo naukowe

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