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Tytuł:
Transcription Factor GLI1 Induces IL-6-Mediated Inflammatory Response and Facilitates the Progression of Adamantinomatous Craniopharyngioma.
Autorzy:
Zhao J; Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
Yang Y; Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
Pan Y; Institute of Radiation Therapy and Tumor Critical Care of Zhengzhou University, Zhengzhou 450052, P.R. China.
Zhou P; Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
Wang J; Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
Zheng Y; Institute of Radiation Therapy and Tumor Critical Care of Zhengzhou University, Zhengzhou 450052, P.R. China.
Zhang X; Henan Key Laboratory of Molecular Radiotherapy, Zhengzhou 450052, P.R. China.
Zhai S; Henan Key Laboratory of Molecular Radiotherapy, Zhengzhou 450052, P.R. China.
Zhang X; Institute of Radiation Therapy and Tumor Critical Care of Zhengzhou University, Zhengzhou 450052, P.R. China.
Li L; Comprehensive Hyperthermia Center, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
Yang D; Department of Radiotherapy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, P.R. China.
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Źródło:
ACS chemical neuroscience [ACS Chem Neurosci] 2023 Sep 20; Vol. 14 (18), pp. 3347-3356. Date of Electronic Publication: 2023 Sep 10.
Typ publikacji:
Journal Article
MeSH Terms:
Craniopharyngioma*/genetics
Pituitary Neoplasms*/genetics
Animals ; Mice ; Hedgehog Proteins ; Transcription Factors ; Interleukin-6 ; Mice, Nude ; Zinc Finger Protein GLI1/genetics ; Inflammation
Czasopismo naukowe
Szczegóły
Tytuł:
Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells.
Autorzy:
Wang Z; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Li W; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Wang X; Shanghai Lung Tumor Clinical Medical Center, Shanghai Chest Hospital, Shanghai Jiao Tong University, Shanghai 200030, China.
Zhu Q; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.; Department of General Surgery, Xinhua Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai 200092, China.
Liu L; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Qiu S; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.; University of Shanghai for Science and Technology, School of Medical Instrument and Food Engineering, Shanghai 200093, China.
Zou L; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Liu K; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Li G; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Miao H; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Yang Y; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Jiang C; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Liu Y; Department of General Surgery, Changzhou Hospital of Traditional Chinese Medicine Nanjing University of Chinese Medicine, Changzhou, Jiangsu 213004, China.
Shao R; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.; Department of Pharmacology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Wang X; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
Liu Y; Department of Biliary-Pancreatic Surgery, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200127, China.; State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.; Shanghai Research Center of Biliary Tract Disease, Shanghai 200092, China.
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Źródło:
Chinese medical journal [Chin Med J (Engl)] 2023 Sep 20; Vol. 136 (18), pp. 2210-2220. Date of Electronic Publication: 2023 Jul 24.
Typ publikacji:
Journal Article
MeSH Terms:
Gallbladder Neoplasms*/drug therapy
Gallbladder Neoplasms*/genetics
Chalcones*/pharmacology
Ferroptosis*
Carcinoma in Situ*
Animals ; Mice ; Kelch-Like ECH-Associated Protein 1 ; Glutathione Disulfide ; Mice, Nude ; Reactive Oxygen Species ; NF-E2-Related Factor 2/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
NADPH oxidase 4 facilitates progression of chondrosarcoma via generation of reactive oxygen species.
Autorzy:
Jun Z; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
Lei W; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
Ce F; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
Wen Tao R; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
Xiang Hui M; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
Ci Nan Q; Department of Orthopedics, Anhui Provincial Cancer Hospital, China.
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Źródło:
Acta biochimica Polonica [Acta Biochim Pol] 2023 Sep 18; Vol. 70 (3), pp. 685-692.
Typ publikacji:
Journal Article
MeSH Terms:
Chondrosarcoma*/genetics
Bone Neoplasms*
Animals ; Mice ; Humans ; NADPH Oxidase 4/genetics ; Reactive Oxygen Species ; Mice, Nude ; Poly(ADP-ribose) Polymerase Inhibitors ; Proto-Oncogene Proteins c-akt ; bcl-2-Associated X Protein/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Steroidal saponins PPI/CCRIS/PSV induce cell death in pancreatic cancer cell through GSDME-dependent pyroptosis.
Autorzy:
Liu Y; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing, 210009, PR China.
Zhang W; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing, 210009, PR China.
Zhou H; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing, 210009, PR China.
Chen J; State Key Laboratory of Natural Medicines, China Pharmaceutical University, No. 24 Tongjia Lane, Nanjing, 210009, PR China; Department of Pharmacognosy, School of Traditional Chinese Pharmacy, China Pharmaceutical University, No. 639 Longmian Avenue, Nanjing, 211198, PR China. Electronic address: .
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Źródło:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2023 Sep 17; Vol. 673, pp. 51-58. Date of Electronic Publication: 2023 Jun 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Pyroptosis*
Pancreatic Neoplasms*/drug therapy
Humans ; Animals ; Mice ; Mice, Nude ; Gasdermins ; Cell Death ; Disease Models, Animal ; Caspase 3/metabolism
SCR Disease Name:
Pancreatic Carcinoma
Czasopismo naukowe
Szczegóły
Tytuł:
Transcription factor Dp-1 knockdown downregulates thymidine kinase 1 expression to protect against proliferation and epithelial-mesenchymal transition in cervical cancer.
Autorzy:
Wu M; Department of Gynecologic Oncology, Hunan Cancer Hospital, Changsha, Hunan, 410013, People's Republic of China.
Ye M; Department of Urology Surgery, Hunan Cancer Hospital, No. 283, Tongzipo Road, Yuelu District, Changsha, Hunan, 410013, People's Republic of China. .
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Źródło:
Functional & integrative genomics [Funct Integr Genomics] 2023 Sep 16; Vol. 23 (4), pp. 301. Date of Electronic Publication: 2023 Sep 16.
Typ publikacji:
Journal Article
MeSH Terms:
Uterine Cervical Neoplasms*/genetics
Humans ; Animals ; Mice ; Female ; Transcription Factor DP1 ; Epithelial-Mesenchymal Transition ; Mice, Nude ; Cell Proliferation
Czasopismo naukowe
Szczegóły
Tytuł:
In vivo CRISPR screen identifies LTN1 as a novel tumor suppressor ubiquitinating insulin-like growth factor 2 mRNA-binding protein 1 in hepatocellular carcinoma.
Autorzy:
Peng R; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Cao J; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Zhang C; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Zhou J; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Su BB; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Tu DY; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Jiang GQ; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Jin SJ; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
Xu YP; Department of Gastroenterology, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
Bai DS; Department of Hepatobiliary Surgery, Clinical Medical College, Yangzhou University, Yangzhou, China.
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Źródło:
Hepatology communications [Hepatol Commun] 2023 Sep 15; Vol. 7 (10). Date of Electronic Publication: 2023 Sep 15 (Print Publication: 2023).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/genetics
Liver Neoplasms*/genetics
Somatomedins*
Animals ; Mice ; Humans ; Chromatography, Liquid ; Clustered Regularly Interspaced Short Palindromic Repeats ; Mice, Nude ; Tandem Mass Spectrometry ; Ligases ; RNA, Messenger
Czasopismo naukowe
Szczegóły
Tytuł:
Hypoxia derived exosomes promote the proliferation and metastasis of colorectal cancer through the regulation of HIF-1α/miR-4299/ZBTB4.
Autorzy:
Wu L; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Xue M; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Lai S; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Chen J; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Lin Y; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Ding N; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Zhong J; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China.
Chen S; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China; Department of Gastroenterology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310000, China. Electronic address: .
Wang L; Department of Gastroenterology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou 310000, China; Institution of Gastroenterology, Zhejiang University, Hangzhou 310000, China; Cancer Center, Zhejiang University, Hangzhou, Zhejiang Province 310058, China. Electronic address: .
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Źródło:
Life sciences [Life Sci] 2023 Sep 15; Vol. 329, pp. 121872. Date of Electronic Publication: 2023 Jun 22.
Typ publikacji:
Journal Article
MeSH Terms:
Exosomes*/metabolism
MicroRNAs*/metabolism
Colorectal Neoplasms*/pathology
Animals ; Mice ; Humans ; Mice, Nude ; Mice, Inbred BALB C ; RNA, Small Interfering/metabolism ; Hypoxia/metabolism ; Cell Proliferation/genetics ; Gene Expression Regulation, Neoplastic ; Cell Line, Tumor ; Cell Movement ; Tumor Microenvironment ; Repressor Proteins/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Quercetin inhibits the metabolism of arachidonic acid by inhibiting the activity of CYP3A4, thereby inhibiting the progression of breast cancer.
Autorzy:
Tang H; Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Wuhou District, Sichuan Province, Chengdu, 610000, People's Republic of China.
Kuang Y; Department of General Surgery, Chongqing Kaizhou District People's Hospital, Chongqing, 400700, People's Republic of China.
Wu W; Department of General Surgery, Chongqing Kaizhou District People's Hospital, Chongqing, 400700, People's Republic of China.
Peng B; Department of Pancreatic Surgery, West China Hospital, Sichuan University, No. 37, Guoxue Lane, Wuhou District, Sichuan Province, Chengdu, 610000, People's Republic of China. .
Fu Q; Department of Oncology, Chongqing Kaizhou District People's Hospital, No. 8, Ankang Road, Hanfeng Street, Kaizhou District, Chongqing, 400700, People's Republic of China. .
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Źródło:
Molecular medicine (Cambridge, Mass.) [Mol Med] 2023 Sep 14; Vol. 29 (1), pp. 127. Date of Electronic Publication: 2023 Sep 14.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/drug therapy
Biological Products*
Humans ; Animals ; Mice ; Female ; Arachidonic Acid ; Cytochrome P-450 CYP3A ; Quercetin/pharmacology ; Quercetin/therapeutic use ; Chromatography, Liquid ; Mice, Nude ; Tandem Mass Spectrometry
Czasopismo naukowe
Szczegóły
Tytuł:
Impact of chemotherapeutic agents on liver microenvironment: oxaliplatin create a pro-metastatic landscape.
Autorzy:
Ma Y; Center of Biotherapy, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, 100730, People's Republic of China.
Guo C; Center of Biotherapy, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, 100730, People's Republic of China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China.
Wang X; Center of Biotherapy, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, 100730, People's Republic of China.
Wei X; Center of Biotherapy, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, 100730, People's Republic of China. .
Ma J; Center of Biotherapy, Beijing Hospital, National Center of Gerontology; Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Graduate School of Peking Union Medical College, Beijing, 100730, People's Republic of China. .; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, 100049, People's Republic of China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Sep 11; Vol. 42 (1), pp. 237. Date of Electronic Publication: 2023 Sep 11.
Typ publikacji:
Meta-Analysis; Journal Article
MeSH Terms:
Liver Neoplasms*/drug therapy
Colorectal Neoplasms*/drug therapy
Animals ; Mice ; Oxaliplatin/pharmacology ; CD8-Positive T-Lymphocytes ; Mice, Nude ; Immunosuppressive Agents ; Tumor Microenvironment
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Knockdown of ANXA10 induces ferroptosis by inhibiting autophagy-mediated TFRC degradation in colorectal cancer.
Autorzy:
Wang X; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Zhou Y; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Ning L; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen J; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Chen H; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Li X; Division of Gastroenterology and Hepatology, Shanghai Institute of Digestive Disease, NHC Key Laboratory of Digestive Diseases, State Key Laboratory for Oncogenes and Related Genes, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China. lxb_.
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Źródło:
Cell death & disease [Cell Death Dis] 2023 Sep 04; Vol. 14 (9), pp. 588. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Ferroptosis*/genetics
Lung Neoplasms*/genetics
Colorectal Neoplasms*/genetics
Humans ; Animals ; Mice ; Transferrin ; Mice, Nude ; Reactive Oxygen Species ; Receptors, Transferrin/genetics ; Autophagy/genetics ; Membrane Proteins ; Lipids ; Annexins/genetics
Czasopismo naukowe
Szczegóły
Tytuł:
Preparation and Evaluation of [ F]AlF-NOTA-PBB for PET Imaging of Cyclin-dependent Kinase 4/6 in Tumors.
Autorzy:
Xiao D; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
Gan Q; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
Duan X; Department of Nuclear Medicine, Peking University First Hospital, Beijing 100034, China.
Wang Q; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
Jiang Y; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
Han P; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
Zhang J; Key Laboratory of Radiopharmaceuticals of Ministry of Education, NMPA Key Laboratory for Research and Evaluation of Radiopharmaceuticals (National Medical Product Administration), College of Chemistry, Beijing Normal University, Beijing 100875, China.
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Źródło:
Molecular pharmaceutics [Mol Pharm] 2023 Sep 04; Vol. 20 (9), pp. 4528-4536. Date of Electronic Publication: 2023 Aug 24.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Neoplasms*/diagnostic imaging
Animals ; Mice ; Cyclin-Dependent Kinase 4 ; Mice, Nude ; Tissue Distribution ; Positron-Emission Tomography ; Chelating Agents
Czasopismo naukowe
Szczegóły
Tytuł:
Circadian gene ARNTL initiates circGUCY1A2 transcription to suppress non-small cell lung cancer progression via miR-200c-3p/PTEN signaling.
Autorzy:
Zhao D; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
Dong Y; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Shulan International Medical College, Zhejiang Shuren University, Hangzhou, Zhejiang, 310011, China.
Duan M; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
He D; Hunan Key Laboratory of Oncotarget Gene, Hunan Cancer Hospital & The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.
Xie Q; Department of Ultrasonic Imaging, Affiliated Hospital of Hunan Traditional Chinese Medicine Research Institute, Changsha, 410006, Hunan, China.
Peng W; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Department of Oncology, Hunan Provincial People's Hospital, the First Affiliated Hospital of Hunan Normal University, Changsha, 410006, Hunan, China.
Cui W; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
Jiang J; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
Cheng Y; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
Zhang H; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.
Tang F; Hunan Key Laboratory of Oncotarget Gene, Hunan Cancer Hospital & The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, 410008, Hunan, China.
Zhang C; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China.; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Gao Y; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. gaoyang_.; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China. gaoyang_.; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. gaoyang_.
Duan C; Department of Thoracic Surgery, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. .; Hunan Engineering Research Center for Pulmonary Nodules Precise Diagnosis & Treatment, Changsha, 410008, Hunan, China. .; Xiangya Lung Cancer Center, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. .; Institute of Medical Sciences, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. .; National Clinical Research Center for Geriatric Disorders, Changsha, 410008, Hunan, China. .
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Źródło:
Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2023 Sep 04; Vol. 42 (1), pp. 229. Date of Electronic Publication: 2023 Sep 04.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Non-Small-Cell Lung*/genetics
Lung Neoplasms*/genetics
Adenocarcinoma of Lung*
Humans ; Animals ; Mice ; ARNTL Transcription Factors ; Mice, Nude ; Phosphatidylinositol 3-Kinases ; Disease Models, Animal ; PTEN Phosphohydrolase/genetics
Czasopismo naukowe
Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
Tytuł:
Matrix stiffness regulates neovascular homeostasis through autophagy in nude mice.
Autorzy:
Wang B; Department of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Yang Y; Department of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Wang Y; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Yang Y; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Li Y; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Hu C; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.
Xue C; Department of Oral Implantology, The Affiliated Stomatological Hospital of Nanjing Medical University, Nanjing, China.; Jiangsu Key Laboratory of Oral Diseases, Nanjing Medical University, Nanjing, China.; Jiangsu Province Engineering Research Center of Stomatological Translational Medicine, Nanjing Medical University, Nanjing, China.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2023 Sep; Vol. 238 (9), pp. 2135-2146. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dextrans*/pharmacology
Autophagy*
Mice ; Animals ; Mice, Nude ; Homeostasis ; Hydrogels/chemistry ; Neovascularization, Physiologic
Czasopismo naukowe
Szczegóły
Tytuł:
CS-NO suppresses inhibits glycolysis and gastric cancer progression through regulating YAP/TAZ signaling pathway.
Autorzy:
Guo N; The Second Oncology Department, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Ma H; Faculty of Medicine, Faculty of Health and Behavioural Sciences, The University of Queensland, Brisbane, QLD, Australia.
Li D; The Second Oncology Department, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Fan H; The Second Oncology Department, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Sun C; The Second Oncology Department, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei Province, China.
Sun Y; The Second Surgical Department, Hebei Province Hospital of Chinese Medicine, Shijiazhuang, Hebei Province, China. .
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Źródło:
Cell biochemistry and biophysics [Cell Biochem Biophys] 2023 Sep; Vol. 81 (3), pp. 561-567. Date of Electronic Publication: 2023 Aug 10.
Typ publikacji:
Journal Article
MeSH Terms:
Stomach Neoplasms*/drug therapy
Stomach Neoplasms*/metabolism
Animals ; Mice ; Glucose Transporter Type 1/metabolism ; Nitric Oxide/metabolism ; Mice, Nude ; Cell Line, Tumor ; Signal Transduction ; Glycolysis ; Cell Proliferation ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Szczegóły
Tytuł:
Hirudin inhibits glioma growth through mTOR-regulated autophagy.
Autorzy:
Ma Y; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.
Wu S; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.
Zhao F; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.
Li H; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.
Li Q; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.
Zhang J; Department of Traditional Chinese Medicine, The Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China.
Li H; Laboratory animal center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.
Yuan Z; Department of Neurology, Institute of Neuroscience, Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and the Ministry of Education of China, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, China.; Guangdong Province Key Laboratory of Brain Function and Disease, Guangzhou, China.; Guangdong-Hong Kong-Macao Greater Bay Area Center for Brain Science and Brain-Inspired Intelligence, Guangzhou, China.
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Źródło:
Journal of cellular and molecular medicine [J Cell Mol Med] 2023 Sep; Vol. 27 (18), pp. 2701-2713. Date of Electronic Publication: 2023 Aug 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hirudins*/pharmacology
Glioma*/pathology
Mice ; Animals ; Humans ; Mice, Nude ; Cell Line, Tumor ; TOR Serine-Threonine Kinases/metabolism ; Cell Proliferation ; Autophagy ; Apoptosis
Czasopismo naukowe
Szczegóły
Tytuł:
USP18 enhances the resistance of BRAF-mutated melanoma cells to vemurafenib by stabilizing cGAS expression to induce cell autophagy.
Autorzy:
Ma ZR; Department of Burns and Plastic Surgery, Children's Hospital of Soochow University, Suzhou 215025, PR China; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China.
Xiong QW; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China; Department of Urology, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Cai SZ; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China; Department of Child and Adolescent Healthcare, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Ding LT; Department of Burn and Plastic Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, PR China.
Yin CH; Department of Burn and Plastic Surgery, Affiliated Hospital of Jiangnan University, Wuxi 214000, PR China.
Xia HL; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China; Department of Urology, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Liu W; Department of Burns and Plastic Surgery, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Dai S; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China.
Zhang Y; Soochow University, Suzhou 215006, PR China.
Zhu ZH; Department of Burns and Plastic Surgery, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Huang ZJ; Department of Burns and Plastic Surgery, Children's Hospital of Soochow University, Suzhou 215025, PR China.
Wang Q; Department of Anesthesiology, Children's Hospital of Soochow University, Suzhou 215025, PR China. Electronic address: q_.
Yan XM; Suzhou Key Laboratory of Congenital Structural Deformities, Suzhou 215025, Jiangsu, PR China; Department of Surgery, Children's Hospital of Soochow University, Suzhou 215025, PR China. Electronic address: xm_.
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2023 Sep; Vol. 122, pp. 110617. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:
Journal Article
MeSH Terms:
Proto-Oncogene Proteins B-raf*/genetics
Melanoma*/drug therapy
Melanoma*/genetics
Melanoma*/pathology
Animals ; Mice ; Humans ; Vemurafenib/pharmacology ; Vemurafenib/therapeutic use ; Mice, Nude ; Indoles/pharmacology ; Indoles/therapeutic use ; Sulfonamides/pharmacology ; Sulfonamides/therapeutic use ; Drug Resistance, Neoplasm/genetics ; Mutation ; Cell Line, Tumor ; Protein Kinase Inhibitors/pharmacology ; Autophagy/genetics ; Nucleotidyltransferases/genetics ; Ubiquitin Thiolesterase/genetics ; Ubiquitin Thiolesterase/pharmacology
Czasopismo naukowe
Szczegóły
Tytuł:
Polydatin radiosensitizes lung cancer while preventing radiation injuries by modulating tumor-infiltrating B cells.
Autorzy:
Guo J; School of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, China.; Department of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Ding W; School of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, China.; Department of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Cai S; Department of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China.
Ren P; The 929th Navy Hospital, Naval Medical University, Shanghai, 200433, China.
Chen F; School of Basic Medicine, Naval Medical University, Shanghai, 200433, China.
Wang J; School of Basic Medicine, Naval Medical University, Shanghai, 200433, China.
Fang K; Department of Medicine College, Jiangnan University, Wuxi, 214000, Jiangsu, China. .
Li B; Department of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China. .
Cai J; School of Public Health and Management, Wenzhou Medical University, Wenzhou, 325035, China. .; Department of Radiation Medicine, College of Naval Medicine, Naval Medical University, Shanghai, 200433, China. .
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Źródło:
Journal of cancer research and clinical oncology [J Cancer Res Clin Oncol] 2023 Sep; Vol. 149 (12), pp. 9529-9542. Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article
MeSH Terms:
B-Lymphocyte Subsets*/pathology
Lung Neoplasms*/drug therapy
Lung Neoplasms*/radiotherapy
Lung Neoplasms*/pathology
Radiation Injuries*
Mice ; Animals ; Mice, Nude ; Cell Line, Tumor ; Radiation Tolerance ; Apoptosis
Czasopismo naukowe
Szczegóły
Tytuł:
TRIM25-mediated ubiquitination of G3BP1 regulates the proliferation and migration of human neuroblastoma cells.
Autorzy:
Yang Y; School of Medicine, Guizhou University, Guiyang 550025, China; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China.
Luo Y; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China; Department of Pain, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China.
Yang C; Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200040, China.
Hu R; School of Medicine, Guizhou University, Guiyang 550025, China; State Key Laboratory of Molecular Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, Shanghai 200031, China. Electronic address: .
Qin X; Department of Thoracic Surgery, Shanghai Pulmonary Hospital, School of Medicine, Tongji University, Shanghai 200433, China. Electronic address: .
Li C; Cancer Center, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai 200040, China. Electronic address: .
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Źródło:
Biochimica et biophysica acta. Gene regulatory mechanisms [Biochim Biophys Acta Gene Regul Mech] 2023 Sep; Vol. 1866 (3), pp. 194954. Date of Electronic Publication: 2023 Jun 10.
Typ publikacji:
Journal Article
MeSH Terms:
Neuroblastoma*/genetics
Animals ; Child ; Humans ; Mice ; Cell Line ; Cell Proliferation/genetics ; Mice, Nude ; Transcription Factors/genetics ; Tripartite Motif Proteins/genetics ; Ubiquitin-Protein Ligases/genetics ; Ubiquitination
Czasopismo naukowe
Szczegóły
Tytuł:
Newcastle disease virus LaSota strain induces apoptosis and activates the TNFα/NF-κB pathway in canine mammary carcinoma cells.
Autorzy:
Wang J; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Li M; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
Li M; Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
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Źródło:
Veterinary and comparative oncology [Vet Comp Oncol] 2023 Sep; Vol. 21 (3), pp. 520-532. Date of Electronic Publication: 2023 Jun 06.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma*/veterinary
Dog Diseases*/therapy
Oncolytic Virotherapy*/veterinary
Oncolytic Viruses*
Rodent Diseases*
Animals ; Dogs ; Mice ; Apoptosis ; Caspase 3/metabolism ; Caspase 8/metabolism ; Cell Line, Tumor ; Mice, Nude ; Newcastle disease virus/metabolism ; NF-kappa B/metabolism ; Tumor Necrosis Factor-alpha/metabolism
Czasopismo naukowe
Szczegóły
Tytuł:
Antitumor activity of galaxamide involved in cell apoptosis and stemness by inhibiting Wnt/β-catenin pathway in cervical cancer.
Autorzy:
Yang G; Department of Pathology, Jinan University School of Medicine, Guangzhou, China.; Department of Chemistry, College of Chemistry and Material Science, Jinan University, Guangzhou, China.
He Y; Department of Medical Statistics, Jinan University School of Medicine, Guangzhou, China.
Chen Y; Department of Gynecology & Obstetrics, The First Affiliated Hospital of Jinan University, Jian University, Guangzhou, China.
Huang Z; Department of Chemistry, College of Chemistry and Material Science, Jinan University, Guangzhou, China.
Huang J; Department of Pathology, Jinan University School of Medicine, Guangzhou, China.
Ren X; Department of Pathology, Jinan University School of Medicine, Guangzhou, China.
Xu S; Department of Chemistry, College of Chemistry and Material Science, Jinan University, Guangzhou, China.
Li P; Department of Pathology, Jinan University School of Medicine, Guangzhou, China.
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Źródło:
Drug development research [Drug Dev Res] 2023 Sep; Vol. 84 (6), pp. 1114-1126. Date of Electronic Publication: 2023 May 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Wnt Signaling Pathway*
Uterine Cervical Neoplasms*/genetics
Female ; Humans ; Animals ; Mice ; HeLa Cells ; beta Catenin/genetics ; Mice, Nude ; Peptides, Cyclic/chemistry ; Peptides, Cyclic/pharmacology ; Apoptosis ; Cell Proliferation ; Cell Line, Tumor
Czasopismo naukowe
Szczegóły
Wyświetlanie 1-20 z 41323

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