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Tytuł:
Noxa inhibits oncogenesis through ZNF519 in gastric cancer and is suppressed by hsa-miR-200b-3p.
Autorzy:
Shi J; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Ding F; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Dai D; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Song X; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Wu X; Department of Vascular, Huaian Hospital Affiliated to Xuzhou Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Yan D; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Han X; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China.
Tao G; Department of Gastrointestinal Surgery, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China. .
Dai W; Department of Gastroenterology, The Affiliated Huaian No. 1 People's Hospital of Nanjing Medical University, Huai'an, Jiangsu, 223300, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2024 Mar 19; Vol. 14 (1), pp. 6568. Date of Electronic Publication: 2024 Mar 19.
Typ publikacji:
Journal Article
MeSH Terms:
MicroRNAs*/genetics
MicroRNAs*/metabolism
Stomach Neoplasms*/pathology
Animals ; Humans ; Mice ; Cell Line, Tumor ; Cell Movement/genetics ; Cell Proliferation/genetics ; Cell Transformation, Neoplastic/genetics ; Gene Expression Regulation, Neoplastic ; Luciferases/metabolism ; Mice, Nude
Czasopismo naukowe
Tytuł:
In-vivo studies of targeted and localized cancer drug release from microporous poly-di-methyl-siloxane (PDMS) devices for the treatment of triple negative breast cancer.
Autorzy:
Eluu SC; Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, Ifite Awka, 420110, Anambra State, Nigeria.
Obayemi JD; Department of Mechanical Engineering, Higgins Lab, Worcester Polytechnic Institute (WPI), 100 Institute Road, Worcester, MA, 01609, USA.; Department of Biomedical Engineering, Gateway Park Life Sciences and Bioengineering Centre, Worcester Polytechnic Institute, 60 Prescott Street, Worcester, MA, 01609, USA.
Salifu AA; Department of Engineering, Morrissey College of Arts and Science, Boston College, Boston, USA.
Yiporo D; Department of Mechanical Engineering, Ashesi University, Berekuso, Ghana.
Oko AO; Department of Biology and Biotechnology, David Umahi Federal, University of Health Sciences, Uburu, Nigeria.
Aina T; Department of Material Science, African University of Science and Technology, Km 10 Airport Road, Abuja, Nigeria.
Oparah JC; Department of Material Science, African University of Science and Technology, Km 10 Airport Road, Abuja, Nigeria.
Ezeala CC; Department of Material Science, African University of Science and Technology, Km 10 Airport Road, Abuja, Nigeria.
Etinosa PO; Department of Mechanical Engineering, Higgins Lab, Worcester Polytechnic Institute (WPI), 100 Institute Road, Worcester, MA, 01609, USA.
Ugwu CM; Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, Ifite Awka, 420110, Anambra State, Nigeria.
Esimone CO; Department of Pharmaceutical Microbiology and Biotechnology, Nnamdi Azikiwe University, Ifite Awka, 420110, Anambra State, Nigeria.
Soboyejo WO; Department of Mechanical Engineering, Higgins Lab, Worcester Polytechnic Institute (WPI), 100 Institute Road, Worcester, MA, 01609, USA. .; Department of Biomedical Engineering, Gateway Park Life Sciences and Bioengineering Centre, Worcester Polytechnic Institute, 60 Prescott Street, Worcester, MA, 01609, USA. .; Department of Engineering, SUNY Polytechnic Institute, 100 Seymour Rd, Utica, NY, 13502, USA. .
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Źródło:
Scientific reports [Sci Rep] 2024 Jan 02; Vol. 14 (1), pp. 31. Date of Electronic Publication: 2024 Jan 02.
Typ publikacji:
Journal Article
MeSH Terms:
Triple Negative Breast Neoplasms*/drug therapy
Antineoplastic Agents*/pharmacology
Antineoplastic Agents*/therapeutic use
Humans ; Female ; Animals ; Mice ; Siloxanes ; Receptors, LHRH/genetics ; Mice, Nude ; Gonadotropin-Releasing Hormone/pharmacology ; Cell Line, Tumor
Czasopismo naukowe
Tytuł:
Novel PD-L1- and collagen-expressing patient-derived cell line of undifferentiated pleomorphic sarcoma (JBT19) as a model for cancer immunotherapy.
Autorzy:
Taborska P; Department of Immunology, Second Faculty of Medicine, Charles University, and Motol University Hospital, V Uvalu 84, 150 06 Praha 5, Prague, Czech Republic.
Lukac P; Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.; Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic.
Stakheev D; Department of Immunology, Second Faculty of Medicine, Charles University, and Motol University Hospital, V Uvalu 84, 150 06 Praha 5, Prague, Czech Republic.; Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Rajsiglova L; Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.; Department of Cell Biology, Faculty of Science, Charles University, Prague, Czech Republic.
Kalkusova K; Department of Immunology, Second Faculty of Medicine, Charles University, and Motol University Hospital, V Uvalu 84, 150 06 Praha 5, Prague, Czech Republic.
Strnadova K; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.; First Faculty of Medicine, BIOCEV, Charles University, Vestec, Czech Republic.
Lacina L; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.; First Faculty of Medicine, BIOCEV, Charles University, Vestec, Czech Republic.; Department of Dermatovenerology, First Faculty of Medicine, Charles University, and General University Hospital, Prague, Czech Republic.
Dvorankova B; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.; First Faculty of Medicine, BIOCEV, Charles University, Vestec, Czech Republic.
Novotny J; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Kolar M; Laboratory of Genomics and Bioinformatics, Institute of Molecular Genetics of the Czech Academy of Sciences, Prague, Czech Republic.
Vrana M; HLA Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Cechova H; HLA Department, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Ransdorfova S; Department of Cytogenetics, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Valerianova M; Department of Cytogenetics, Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
Smetana K Jr; Institute of Anatomy, First Faculty of Medicine, Charles University, Prague, Czech Republic.; First Faculty of Medicine, BIOCEV, Charles University, Vestec, Czech Republic.
Vannucci L; Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic.
Smrz D; Department of Immunology, Second Faculty of Medicine, Charles University, and Motol University Hospital, V Uvalu 84, 150 06 Praha 5, Prague, Czech Republic. .; Laboratory of Immunotherapy, Institute of Microbiology of the Czech Academy of Sciences, Prague, Czech Republic. .
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Źródło:
Scientific reports [Sci Rep] 2023 Nov 04; Vol. 13 (1), pp. 19079. Date of Electronic Publication: 2023 Nov 04.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sarcoma*/pathology
Histiocytoma, Malignant Fibrous*
Mice ; Animals ; Humans ; B7-H1 Antigen/metabolism ; Mice, Nude ; Ligands ; Immunotherapy ; Cell Line
Czasopismo naukowe
Tytuł:
IL-8 is a novel prometastatic chemokine in intrahepatic cholangiocarcinoma that induces CXCR2-PI3K/AKT signaling upon CD97 activation.
Autorzy:
Meng ZW; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fujian Medical University Cancer Center, 29 Xinquan Road, Fuzhou, 350001, China.
Zhang L; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China.; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China.
Cai XR; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fujian Medical University Cancer Center, 29 Xinquan Road, Fuzhou, 350001, China.
Wang X; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China.; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China.
She FF; Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China. .; Fujian Key Laboratory of Tumor Microbiology, Fujian Medical University, 1 Xueyuan Road, Minhou, Fuzhou, 350108, China. .
Chen YL; Department of Hepatobiliary Surgery and Fujian Institute of Hepatobiliary Surgery, Fujian Medical University Union Hospital, Fujian Medical University Cancer Center, 29 Xinquan Road, Fuzhou, 350001, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 31; Vol. 13 (1), pp. 18711. Date of Electronic Publication: 2023 Oct 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Bile Duct Neoplasms*/metabolism
Cholangiocarcinoma*/metabolism
Animals ; Mice ; Bile Ducts, Intrahepatic/pathology ; Cell Line, Tumor ; Cell Movement/physiology ; Epithelial-Mesenchymal Transition/physiology ; Interleukin-8 ; Mice, Nude ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/metabolism ; Tumor Microenvironment ; Humans
Czasopismo naukowe
Tytuł:
METTL3/IGF2BP2 axis affects the progression of colorectal cancer by regulating m6A modification of STAG3.
Autorzy:
Yi J; The Department of General Surgery 2, Zhuzhou Central Hospital (Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University), 116 Changjiang South Road, Tianyuan District, Zhuzhou, 412007, Hunan, China.
Peng F; The Department of General Surgery 2, Zhuzhou Central Hospital (Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University), 116 Changjiang South Road, Tianyuan District, Zhuzhou, 412007, Hunan, China.
Zhao J; The Department of Operating Room, Zhuzhou Central Hospital (Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University), Zhuzhou, 412007, China.
Gong X; The Department of General Surgery 2, Zhuzhou Central Hospital (Zhuzhou Hospital Affiliated to Xiangya School of Medicine, Central South University), 116 Changjiang South Road, Tianyuan District, Zhuzhou, 412007, Hunan, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 12; Vol. 13 (1), pp. 17292. Date of Electronic Publication: 2023 Oct 12.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Methyltransferases*/genetics
Colorectal Neoplasms*/genetics
Humans ; Animals ; Mice ; Mice, Nude ; Adenosine ; Disease Models, Animal ; RNA, Messenger ; Cell Cycle Proteins ; RNA-Binding Proteins/genetics
Czasopismo naukowe
Tytuł:
High-fat diet promotes tumor growth in the patient-derived orthotopic xenograft (PDOX) mouse model of ER positive endometrial cancer.
Autorzy:
Shen K; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Shen D; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Drug Discovery and Development, School of Pharmaceutical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450052, Henan, China.
Jin D; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zheng Y; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.; Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China, Key Laboratory of Henan Province for Drug Quality and Evaluation, Institute of Drug Discovery and Development, School of Pharmaceutical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, 450052, Henan, China.; State Key Laboratory of Esophageal Cancer Prevention & Treatment; Academy of Medical Sciences, Zhengzhou University, 100 Kexue Avenue, Zhengzhou, Henan, China.
Zhu Y; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhao X; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Zhang Z; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Wang N; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Chen H; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Yang L; Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. .; Zhengzhou Key Laboratory of Endometrial Disease Prevention and Treatment, Zhengzhou, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Oct 02; Vol. 13 (1), pp. 16537. Date of Electronic Publication: 2023 Oct 02.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Sarcoma*/pathology
Endometrial Neoplasms*
Female ; Humans ; Mice ; Animals ; Mice, Nude ; Heterografts ; Diet, High-Fat/adverse effects ; Xenograft Model Antitumor Assays ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Taraxasterol suppresses the proliferation and tumor growth of androgen-independent prostate cancer cells through the FGFR2-PI3K/AKT signaling pathway.
Autorzy:
Yang J; School of Clinical Medicine, Dali University, Dali, 671013, Yunnan, China.
Xin C; School of Basic Medical Sciences, Dali University, 22 Wanhua Road, Dali, 671013, Yunnan, China.
Yin G; The First Affiliated Hospital of Dali University, Dali, 671013, Yunnan, China.
Li J; School of Basic Medical Sciences, Dali University, 22 Wanhua Road, Dali, 671013, Yunnan, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 11; Vol. 13 (1), pp. 13072. Date of Electronic Publication: 2023 Aug 11.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Proto-Oncogene Proteins c-akt*/metabolism
Prostatic Neoplasms*/pathology
Male ; Animals ; Mice ; Humans ; Phosphatidylinositol 3-Kinases/metabolism ; Androgens/pharmacology ; Cyclin D1/metabolism ; Mice, Nude ; Cell Line, Tumor ; Cell Proliferation ; Signal Transduction ; Receptor, Fibroblast Growth Factor, Type 2/metabolism
Czasopismo naukowe
Tytuł:
Effects of dexmedetomidine on A549 non-small cell lung cancer growth in a clinically relevant surgical xenograft model.
Autorzy:
Jun JH; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Shim JK; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Oh JE; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.
Kim KS; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Kwak YL; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea.; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.
Soh S; Anesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. .; Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 01; Vol. 13 (1), pp. 12471. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Dexmedetomidine*/pharmacology
Carcinoma, Non-Small-Cell Lung*/drug therapy
Lung Neoplasms*/drug therapy
Humans ; Mice ; Animals ; Inflammasomes/metabolism ; Interleukin-18/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Interleukin-10 ; Heterografts ; Mice, Nude ; Inflammation/pathology
Czasopismo naukowe
Tytuł:
Therapeutic potential of pomegranate juice-derived nanovesicles in nude mouse benign prostatic hyperplasia (BPH) xenograft model.
Autorzy:
Sreekumar A; Department of Biochemistry and Molecular Biology, Augusta University, 1410 Laney Walker Boulevard, Augusta, GA, 30912, USA.
Simmons MN; Department of Urology, Augusta University, Augusta, USA.
Lee TJ; Department of Center for Biotechnology and Genomic Medicine, Augusta University, Augusta, USA.
Sharma A; Department of Center for Biotechnology and Genomic Medicine, Augusta University, Augusta, USA.
Saini S; Department of Biochemistry and Molecular Biology, Augusta University, 1410 Laney Walker Boulevard, Augusta, GA, 30912, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Aug 01; Vol. 13 (1), pp. 12427. Date of Electronic Publication: 2023 Aug 01.
Typ publikacji:
Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't
MeSH Terms:
Prostatic Hyperplasia*/drug therapy
Prostatic Hyperplasia*/metabolism
Pomegranate*
Humans ; Male ; Mice ; Animals ; Mice, Nude ; Heterografts ; Prostate/metabolism
Czasopismo naukowe
Tytuł:
ESS2 controls prostate cancer progression through recruitment of chromodomain helicase DNA binding protein 1.
Autorzy:
Takahashi S; Department of Urology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan. .; Department of Urology, The Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan. .
Takada I; Department of Urology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.; Division of Biochemistry, Department of Biomedical Sciences, School of Medicine, Nihon University, Itabashi-Ku, Tokyo, 173-8610, Japan.
Hashimoto K; Department of Urology, The Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
Yokoyama A; Department of Molecular Endocrinology, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8575, Japan.
Nakagawa T; Department of Urology, Teikyo University School of Medicine, 2-11-1 Kaga, Itabashi-Ku, Tokyo, 173-8605, Japan.
Makishima M; Division of Biochemistry, Department of Biomedical Sciences, School of Medicine, Nihon University, Itabashi-Ku, Tokyo, 173-8610, Japan.
Kume H; Department of Urology, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato-Ku, Tokyo, 108-8639, Japan.; Department of Urology, The Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo, 113-8655, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Jul 31; Vol. 13 (1), pp. 12355. Date of Electronic Publication: 2023 Jul 31.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prostate*/pathology
Prostatic Neoplasms, Castration-Resistant*/drug therapy
Male ; Animals ; Mice ; Humans ; Mice, Nude ; Cell Line, Tumor ; DNA-Binding Proteins/genetics ; NF-kappa B/metabolism ; Neoplastic Processes ; Poly(ADP-ribose) Polymerase Inhibitors/therapeutic use ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Breviscapine regulates the proliferation, migration, invasion, and apoptosis of colorectal cancer cells via the PI3K/AKT pathway.
Autorzy:
Niu P; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China.
Liu F; Beijing Viewsolid Biotechnology Co., Ltd., Beijing, 100195, China.
Lei F; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China.
Peng J; Department of Traditional Chinese Medicine, Peking University Shougang Hospital, Beijing, 100144, China.
Wang Y; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China.
Zhao J; Department of Traditional Chinese Medicine, Peking University Shougang Hospital, Beijing, 100144, China.
Gao Z; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China.
Gao Q; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China.
Gu J; Department of Gastrointestinal Surgery, Peking University Shougang Hospital, No. 9, Jinyuanzhuang Road, The Shijingshan District, Beijing, 100144, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jun 14; Vol. 13 (1), pp. 9674. Date of Electronic Publication: 2023 Jun 14.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Phosphatidylinositol 3-Kinases*
Colorectal Neoplasms*
Animals ; Mice ; Proto-Oncogene Proteins c-akt ; Mice, Nude ; Neoplastic Processes ; Apoptosis ; Cell Proliferation
Czasopismo naukowe
Tytuł:
Novel in vivo endometriotic models associated eutopic endometrium by implanting menstrual blood-derived stromal cells from patients with endometriosis.
Autorzy:
Zhang Y; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
He T; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Lin T; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Guo Q; Department of Galactophore, Beijing University of Chinese Medicine Affiliated Third Hospital, Beijing, China.
Huo C; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Roberts SZ; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Yang M; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Yang S; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Gao L; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Zhang W; The Third School of Clinical Medicine, Beijing University of Chinese Medicine, Beijing, China.
Li C; The School of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No. 11. Beisanhuang Dong Street, Chaoyang District, Beijing, 100029, China. .
Ma X; Department of Gynecology, Beijing University of Chinese Medicine Affiliated Third Hospital, No. 51. Xiaoguan Street, Chaoyang District, Beijing, 100029, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 May 23; Vol. 13 (1), pp. 8347. Date of Electronic Publication: 2023 May 23.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Endometriosis*
Animals ; Mice ; Humans ; Female ; Mice, Nude ; Osteogenesis ; Stromal Cells ; Patients
Czasopismo naukowe
Tytuł:
Engineered tissue vascularization and engraftment depends on host model.
Autorzy:
Brady EL; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.
Prado O; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.
Johansson F; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.
Mitchell SN; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.
Martinson AM; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA.
Karbassi E; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA.
Reinecke H; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA.
Murry CE; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA.
Davis J; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA.; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA.; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA.
Stevens KR; Department of Bioengineering, University of Washington, Seattle, WA, 98195, USA. .; Institute for Stem Cell and Regenerative Medicine, Seattle, WA, 98195, USA. .; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA. .; Center for Cardiovascular Biology, University of Washington, Seattle, WA, 98195, USA. .; Brotman Baty Institute, Seattle, WA, 98195, USA. .
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Źródło:
Scientific reports [Sci Rep] 2023 Feb 03; Vol. 13 (1), pp. 1973. Date of Electronic Publication: 2023 Feb 03.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:
Tissue Engineering*/methods
Heart Transplantation*
Mice ; Rats ; Humans ; Animals ; Mice, Nude ; Rats, Nude ; Tissue Donors ; Myocytes, Cardiac/metabolism ; Neovascularization, Pathologic/metabolism ; Neovascularization, Physiologic ; Tissue Scaffolds
Czasopismo naukowe
Tytuł:
Cyperotundone combined with adriamycin induces apoptosis in MCF-7 and MCF-7/ADR cancer cells by ROS generation and NRF2/ARE signaling pathway.
Autorzy:
Shao W; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, People's Republic of China.; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.
Wang X; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.; RemeGen, Ltd, 58 Middle Beijing Road, Yantai Economic & Technological Development Area, Yantai, 264006, Shandong, People's Republic of China.
Liu Z; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.
Song X; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, People's Republic of China.; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.
Wang F; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.
Liu X; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, People's Republic of China.; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China.
Yu Z; First Clinical College, Shandong University of Traditional Chinese Medicine, Jinan, 250014, Shandong, People's Republic of China. .; Breast Cancer CenterShandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Shandong First Medical University, Jinan, 250117, Shandong, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 25; Vol. 13 (1), pp. 1384. Date of Electronic Publication: 2023 Jan 25.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Doxorubicin*/pharmacology
Doxorubicin*/therapeutic use
Breast Neoplasms*/pathology
Humans ; Animals ; Mice ; Female ; MCF-7 Cells ; Reactive Oxygen Species/pharmacology ; NF-E2-Related Factor 2/metabolism ; Mice, Nude ; Drug Resistance, Neoplasm ; Signal Transduction ; Apoptosis
Czasopismo naukowe
Tytuł:
Effects of a monoclonal antibody against (pro)renin receptor on gliomagenesis.
Autorzy:
Fujimori T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan. .
Shibayama Y; Department of Pharmacology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Kanda T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Suzuki K; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Ogawa D; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Ishikawa R; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Kadota K; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Matsunaga T; Department of Diagnostic Pathology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Tamiya T; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
Nishiyama A; Department of Pharmacology, Kagawa University Faculty of Medicine, Kagawa, Japan.
Miyake K; Department of Neurological Surgery, Kagawa University Faculty of Medicine, 1750-1 Miki-cho, Kita-gun, Kagawa, 761-0793, Japan.
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 16; Vol. 13 (1), pp. 808. Date of Electronic Publication: 2023 Jan 16.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Glioblastoma*/drug therapy
Glioblastoma*/genetics
Glioma*/genetics
Mice ; Animals ; Humans ; Prorenin Receptor ; Antibodies, Monoclonal/metabolism ; Mice, Nude ; Cell Line, Tumor ; Wnt Signaling Pathway/genetics ; Cell Proliferation ; beta Catenin/metabolism ; Gene Expression Regulation, Neoplastic
Czasopismo naukowe
Tytuł:
Engineered nanovesicles from stromal vascular fraction promote angiogenesis and adipogenesis inside decellularized adipose tissue through encapsulating growth factors.
Autorzy:
Tu J; Department of Plastic, Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, China.
Zeng Y; Department of Dermatology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
An R; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Sun J; Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Wen H; Department of Plastic, Medical Center of Burn Plastic and Wound Repair, The First Affiliated Hospital of Nanchang University, Nanchang University, Nanchang, China. .
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Źródło:
Scientific reports [Sci Rep] 2023 Jan 13; Vol. 13 (1), pp. 750. Date of Electronic Publication: 2023 Jan 13.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Adipogenesis*
Stromal Vascular Fraction*
Mice ; Animals ; Endothelial Cells ; Mice, Nude ; Stromal Cells/metabolism ; Adipose Tissue
Czasopismo naukowe
Tytuł:
Effects of different applied voltages of irreversible electroporation on prostate cancer in a mouse model.
Autorzy:
Kim HB; Department of Biosystems & Biomaterials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Zeng CH; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Kim Y; Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Jeong S; Department of Biosystems & Biomaterials Science and Engineering, Seoul National University, Seoul, 08826, Republic of Korea.
Kim SH; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Kang JM; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Park Y; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Won DS; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Kim JW; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Ryu DS; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea.
Lim B; Department of Urology, Asan Medical Center, University of Ulsan College of Medicine, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea. .
Park JH; Biomedical Engineering Research Center, Asan Medical Center, Asan Institute for Life Sciences, 88 Olympic-Ro 43-Gil, Songpa-Gu, Seoul, 05505, Republic of Korea. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 26; Vol. 12 (1), pp. 22336. Date of Electronic Publication: 2022 Dec 26.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Electroporation*/methods
Prostatic Neoplasms*/therapy
Humans ; Male ; Animals ; Mice ; Mice, Nude ; Disease Models, Animal ; Computer Simulation
Czasopismo naukowe
Tytuł:
MKL-1-induced PINK1-AS overexpression contributes to the malignant progression of hepatocellular carcinoma via ALDOA-mediated glycolysis.
Autorzy:
Wang J; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China.
Zhang HM; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China.
Dai ZT; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China.
Huang Y; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China.
Liu H; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China.
Chen Z; Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China.
Wu Y; Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China. .; Department of Radiation Oncology, Hubei Cancer Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430079, Hubei, China. .
Liao XH; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Wuhan, 430081, Hubei, People's Republic of China. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 09; Vol. 12 (1), pp. 21283. Date of Electronic Publication: 2022 Dec 09.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Carcinoma, Hepatocellular*/pathology
Liver Neoplasms*/pathology
MicroRNAs*/genetics
MicroRNAs*/metabolism
Mice ; Animals ; Humans ; Fructose-Bisphosphate Aldolase/genetics ; Fructose-Bisphosphate Aldolase/metabolism ; Gene Expression Regulation, Neoplastic ; Cell Proliferation/genetics ; Cell Line, Tumor ; Glycolysis/genetics ; Mice, Nude
Czasopismo naukowe
Tytuł:
Hair follicle associated pluripotent (HAP) stem cells jump from transplanted whiskers to pelage follicles and stimulate hair growth.
Autorzy:
Obara K; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA. .; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA. .; Department of Dermatology, Kitasato University School of Medicine, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. .
Reynoso J; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA.
Hamada Y; Department of Dermatology, Kitasato University School of Medicine, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan.
Aoki Y; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA.; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Kubota Y; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA.; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Masaki N; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA.; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA.
Amoh Y; Department of Dermatology, Kitasato University School of Medicine, Minami Ward, Sagamihara, Kanagawa, 252-0374, Japan. .
Hoffman RM; AntiCancer, Inc., 7917 Ostrow Street, San Diego, CA, 92111, USA. .; Department of Surgery, University of California San Diego, San Diego, CA, 92103, USA. .
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Źródło:
Scientific reports [Sci Rep] 2022 Dec 07; Vol. 12 (1), pp. 21174. Date of Electronic Publication: 2022 Dec 07.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hair Follicle*
Alopecia*
Animals ; Mice ; Mice, Nude ; Stem Cells
Czasopismo naukowe
Tytuł:
Efficacy of PACE4 pharmacotherapy in JHU-LNCaP-SM preclinical model of androgen independent prostate cancer.
Autorzy:
Mekdad N; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada. .; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada. .; Département de Biochimie et Génomique Fonctionnelle, Université de Sherbrooke, Sherbrooke, QC, Canada. .
Tran TMH; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.; Département de Biochimie et Génomique Fonctionnelle, Université de Sherbrooke, Sherbrooke, QC, Canada.; Faculté des Sciences, Département de Chimie, Université de Sherbrooke, Sherbrooke, QC, Canada.
Desjardins R; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.
Kwiatkowska A; Institut de Pharmacologie de Sherbrooke, Université de Sherbrooke, Sherbrooke, QC, Canada.; Faculté de Médecine et des Sciences de la Santé, Université de Sherbrooke, Sherbrooke, QC, Canada.
Couture F; TransBIOTech, Lévis, QC, Canada. .
Day R; PhenoSwitch Bioscience, Sherbrooke, QC, Canada.
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Źródło:
Scientific reports [Sci Rep] 2022 Oct 19; Vol. 12 (1), pp. 17489. Date of Electronic Publication: 2022 Oct 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Androgens*/metabolism
Prostatic Neoplasms*/pathology
Mice ; Animals ; Male ; Humans ; Mice, Nude ; Cell Line, Tumor ; Proprotein Convertases/metabolism ; Protein Isoforms ; Amino Acids, Basic ; Cell Proliferation ; Receptors, Androgen
Czasopismo naukowe

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