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Wyszukujesz frazę ""Mice, Transgenic"" wg kryterium: Temat


Tytuł:
Statin administration or blocking PCSK9 alleviates airway hyperresponsiveness and lung fibrosis in high-fat diet-induced obese mice.
Autorzy:
Liang L; Graduate School of Medicine, Yonsei University College of Medicine, Seoul, Korea.; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
Chung SI; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
Guon TE; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.
Park KH; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.; Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Lee JH; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea.; Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea.
Park JW; Institute of Allergy, Yonsei University College of Medicine, Seoul, Korea. .; Division of Allergy and Immunology, Department of Internal Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Korea. .
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Źródło:
Respiratory research [Respir Res] 2024 May 18; Vol. 25 (1), pp. 213. Date of Electronic Publication: 2024 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Mice, Inbred C57BL*
Diet, High-Fat*/adverse effects
Obesity*/drug therapy
Obesity*/metabolism
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/pharmacology
Hydroxymethylglutaryl-CoA Reductase Inhibitors*/therapeutic use
Pulmonary Fibrosis*/prevention & control
Pulmonary Fibrosis*/pathology
Pulmonary Fibrosis*/metabolism
Pulmonary Fibrosis*/drug therapy
Mice, Transgenic*
Animals ; Male ; Mice ; PCSK9 Inhibitors ; Atorvastatin/pharmacology ; Atorvastatin/therapeutic use ; Mice, Obese ; Proprotein Convertase 9/metabolism ; Proprotein Convertase 9/genetics ; Antibodies, Monoclonal/pharmacology ; Antibodies, Monoclonal/therapeutic use ; Bronchial Hyperreactivity/prevention & control ; Bronchial Hyperreactivity/drug therapy ; Bronchial Hyperreactivity/metabolism ; Bronchial Hyperreactivity/physiopathology ; Antibodies, Monoclonal, Humanized
Czasopismo naukowe
Tytuł:
Spatiotemporal dynamics of the CD11c microglial population in the mouse brain and spinal cord from developmental to adult stages.
Autorzy:
Nomaki K; Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Fujikawa R; Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Masuda T; Division of Molecular Neuroimmunology, Medical Institute of Bioregulation, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan.
Tsuda M; Department of Molecular and System Pharmacology, Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan. .; Kyushu University Institute for Advanced Study, 744 Motooka Nishi-ku, Fukuoka, 819-0395, Japan. .
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Źródło:
Molecular brain [Mol Brain] 2024 May 18; Vol. 17 (1), pp. 24. Date of Electronic Publication: 2024 May 18.
Typ publikacji:
Journal Article
MeSH Terms:
Microglia*/metabolism
Microglia*/cytology
Spinal Cord*/growth & development
Brain*/growth & development
Brain*/cytology
Mice, Transgenic*
Animals ; Spatio-Temporal Analysis ; Aging ; CD11c Antigen/metabolism ; Mice, Inbred C57BL ; Mice ; Animals, Newborn
Czasopismo naukowe
Tytuł:
Overexpression of pathogenic tau in astrocytes causes a reduction in AQP4 and GLT1, an immunosuppressed phenotype and unique transcriptional responses to repetitive mild TBI without appreciable changes in tauopathy.
Autorzy:
Ortiz C; The Roskamp Institute, Sarasota, FL, USA. .; The Open University, Milton Keynes, UK. .
Pearson A; The Roskamp Institute, Sarasota, FL, USA.; The Open University, Milton Keynes, UK.
McCartan R; The Roskamp Institute, Sarasota, FL, USA.
Roche S; The Roskamp Institute, Sarasota, FL, USA.
Carothers N; The Roskamp Institute, Sarasota, FL, USA.
Browning M; The Roskamp Institute, Sarasota, FL, USA.
Perez S; Barrow Neurological Institute, Phoenix, AZ, USA.
He B; Barrow Neurological Institute, Phoenix, AZ, USA.
Ginsberg SD; Center for Dementia Research, Nathan Kline Institute, Orangeburg, NY, USA.; Departments of Psychiatry, Neuroscience and Physiology, and NYU Neuroscience Institute, New York University Grossman School of Medicine, New York, NY, USA.
Mullan M; The Roskamp Institute, Sarasota, FL, USA.
Mufson EJ; Barrow Neurological Institute, Phoenix, AZ, USA.
Crawford F; The Roskamp Institute, Sarasota, FL, USA.; The Open University, Milton Keynes, UK.; James A. Haley Veterans Hospital, Tampa, FL, USA.
Ojo J; The Roskamp Institute, Sarasota, FL, USA.; The Open University, Milton Keynes, UK.
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 May 15; Vol. 21 (1), pp. 130. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Astrocytes*/pathology
tau Proteins*/metabolism
tau Proteins*/genetics
Aquaporin 4*/metabolism
Aquaporin 4*/genetics
Tauopathies*/metabolism
Tauopathies*/pathology
Tauopathies*/genetics
Excitatory Amino Acid Transporter 2*/metabolism
Excitatory Amino Acid Transporter 2*/genetics
Excitatory Amino Acid Transporter 2*/biosynthesis
Mice, Transgenic*
Animals ; Mice ; Humans ; Brain Concussion/metabolism ; Brain Concussion/pathology ; Male ; Phenotype ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
Cholecystokinin B receptor agonists alleviates anterograde amnesia in cholecystokinin-deficient and aged Alzheimer's disease mice.
Autorzy:
Zhang N; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, 0000, P.R. China.
Sui Y; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.
Jendrichovsky P; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, 21205, USA.
Feng H; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Department of Neurosurgery, Stanford University, Stanford, CA, 94305, USA.
Shi H; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, 0000, P.R. China.
Zhang X; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; National Engineering Laboratory of Big Data System Computing Technology, Shenzhen University, Shenzhen, 518507, P.R. China.
Xu S; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Laboratory Testing Division, WuXi AppTec (Suzhou) Co., Ltd, Suzhou, 215104, P.R. China.
Sun W; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.; Zilkha Neurogenetic Institute, University of Southern California, Los Angeles, CA, 90033, USA.
Zhang H; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, 0000, P.R. China.
Chen X; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China.
Tortorella MD; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong SAR, 0000, P.R. China. .; Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou, 510530, P.R. China. .
He J; Department of Neuroscience and Biomedical Sciences, City University of Hong Kong, Hong Kong SAR, 0000, P.R. China. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 15; Vol. 16 (1), pp. 109. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/genetics
Alzheimer Disease*/metabolism
Receptor, Cholecystokinin B*/genetics
Receptor, Cholecystokinin B*/agonists
Receptor, Cholecystokinin B*/deficiency
Amnesia, Anterograde*/drug therapy
Cholecystokinin*/metabolism
Mice, Transgenic*
Disease Models, Animal*
Animals ; Mice ; Entorhinal Cortex/drug effects ; Entorhinal Cortex/metabolism ; Male ; Mice, Knockout ; Mice, Inbred C57BL ; Long-Term Potentiation/drug effects ; Hippocampus/metabolism ; Hippocampus/drug effects ; Aging/drug effects
Czasopismo naukowe
Tytuł:
Monocytes release cystatin F dimer to associate with Aβ and aggravate amyloid pathology and cognitive deficits in Alzheimer's disease.
Autorzy:
Li Q; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China.; Department of Laboratory Medicine, Shengjing Hospital of China Medical University, Shenyang, 110004, China.
Li B; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China.
Liu L; Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China.; Department of Neurology, Shenyang Fifth People Hospital, Shenyang, 110023, China.
Wang KJ; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China.
Liu MY; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China.
Deng Y; Department of Environmental Health, School of Public Health, China Medical University, Shenyang, 110122, China.
Li Z; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China.
Zhao WD; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China. .
Wu LY; Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, 100053, China. .
Chen YH; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China. .
Zhang K; Department of Developmental Cell Biology, Key Laboratory of Cell Biology,, Ministry of Public Health, China Medical University, 77 Puhe Road, Shenyang, 110122, China. .
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Źródło:
Journal of neuroinflammation [J Neuroinflammation] 2024 May 10; Vol. 21 (1), pp. 125. Date of Electronic Publication: 2024 May 10.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Alzheimer Disease*/pathology
Monocytes*/metabolism
Mice, Transgenic*
Amyloid beta-Peptides*/metabolism
Animals ; Mice ; Humans ; Male ; Female ; Cognitive Dysfunction/metabolism ; Cognitive Dysfunction/pathology ; Aged ; Cystatins/metabolism ; Cystatins/genetics ; Amyloid beta-Protein Precursor/genetics ; Amyloid beta-Protein Precursor/metabolism ; Aged, 80 and over ; Mice, Inbred C57BL
Czasopismo naukowe
Tytuł:
NF-κB1 deficiency promotes macrophage-derived adrenal tumors but decreases neurofibromas in HTLV-I LTR-Tax transgenic mice.
Autorzy:
Song X; Department of Microbiology and Molecular Genetics, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.
Qu Z; Department of Microbiology and Molecular Genetics, UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, United States of America.; Department of Molecular Microbiology and Immunology, Hastings Center for Pulmonary Research, Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, CA, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 09; Vol. 19 (5), pp. e0303138. Date of Electronic Publication: 2024 May 09 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Mice, Transgenic*
Human T-lymphotropic virus 1*/genetics
Human T-lymphotropic virus 1*/pathogenicity
Macrophages*/metabolism
Macrophages*/virology
Gene Products, tax*/metabolism
Gene Products, tax*/genetics
Animals ; Mice ; Humans ; Adrenal Gland Neoplasms/virology ; Adrenal Gland Neoplasms/pathology ; Adrenal Gland Neoplasms/genetics ; Adrenal Gland Neoplasms/metabolism ; NF-kappa B p50 Subunit/metabolism ; NF-kappa B p50 Subunit/genetics ; Terminal Repeat Sequences/genetics
Czasopismo naukowe
Tytuł:
Differential disruptions in population coding along the dorsal-ventral axis of CA1 in the APP/PS1 mouse model of Aβ pathology.
Autorzy:
Chockanathan U; Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Neuroscience Graduate Program, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Medical Scientist Training Program, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Ernest J. Del Monte Institute for Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.
Padmanabhan K; Department of Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Neuroscience Graduate Program, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Medical Scientist Training Program, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Ernest J. Del Monte Institute for Neuroscience, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Center for Visual Sciences, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.; Intellectual and Developmental Disabilities Research Center, University of Rochester School of Medicine and Dentistry, Rochester, New York, United States of America.
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Źródło:
PLoS computational biology [PLoS Comput Biol] 2024 May 06; Vol. 20 (5), pp. e1012085. Date of Electronic Publication: 2024 May 06 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Alzheimer Disease*/physiopathology
Alzheimer Disease*/pathology
Alzheimer Disease*/genetics
Disease Models, Animal*
CA1 Region, Hippocampal*/metabolism
CA1 Region, Hippocampal*/physiopathology
CA1 Region, Hippocampal*/pathology
Amyloid beta-Protein Precursor*/genetics
Amyloid beta-Protein Precursor*/metabolism
Mice, Inbred C57BL*
Mice, Transgenic*
Animals ; Mice ; Amyloid beta-Peptides/metabolism ; Presenilin-1/genetics ; Presenilin-1/metabolism ; Male ; Computational Biology ; Neurons/metabolism ; Neurons/pathology
Czasopismo naukowe
Tytuł:
Selective targeting and modulation of plaque associated microglia via systemic hydroxyl dendrimer administration in an Alzheimer's disease mouse model.
Autorzy:
Henningfield CM; Department of Neurobiology and Behavior, University of California, 3208 Biological Sciences III, Irvine, CA, 92697, USA.
Soni N; Department of Neurobiology and Behavior, University of California, 3208 Biological Sciences III, Irvine, CA, 92697, USA.
Lee RW; Department of Neurobiology and Behavior, University of California, 3208 Biological Sciences III, Irvine, CA, 92697, USA.
Sharma R; Ashvattha Therapeutics, Inc, Redwood City, CA, 94065, USA.
Cleland JL; Ashvattha Therapeutics, Inc, Redwood City, CA, 94065, USA.
Green KN; Department of Neurobiology and Behavior, University of California, 3208 Biological Sciences III, Irvine, CA, 92697, USA. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 06; Vol. 16 (1), pp. 101. Date of Electronic Publication: 2024 May 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Alzheimer Disease*/pathology
Microglia*/drug effects
Microglia*/metabolism
Dendrimers*
Plaque, Amyloid*/drug therapy
Plaque, Amyloid*/pathology
Mice, Transgenic*
Disease Models, Animal*
Animals ; Mice ; Amyloid beta-Peptides/metabolism ; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor/antagonists & inhibitors ; Humans
Czasopismo naukowe
Tytuł:
Loss of Cholinergic and Monoaminergic Afferents in APPswe/PS1ΔE9 Transgenic Mouse Model of Cerebral Amyloidosis Preferentially Occurs Near Amyloid Plaques.
Autorzy:
Lee MK; Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Translational Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.
Chen G; Department of Neuroscience, University of Minnesota, Minneapolis, MN 55455, USA.; Institute for Personalized Medicine in Brain Disorders, The Guangdong-Hongkong-Macao Joint Laboratory of TCM on Brain-Peripheral Homeostasis and Comprehensive Health, School of Chinese Medicine, Jinan University, Guangzhou 510632, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 May 03; Vol. 25 (9). Date of Electronic Publication: 2024 May 03.
Typ publikacji:
Journal Article
MeSH Terms:
Mice, Transgenic*
Plaque, Amyloid*/pathology
Plaque, Amyloid*/metabolism
Disease Models, Animal*
Cholinergic Neurons*/metabolism
Cholinergic Neurons*/pathology
Amyloid beta-Protein Precursor*/genetics
Amyloid beta-Protein Precursor*/metabolism
Alzheimer Disease*/pathology
Alzheimer Disease*/metabolism
Alzheimer Disease*/genetics
Presenilin-1*/genetics
Presenilin-1*/metabolism
Animals ; Mice ; Humans ; Amyloid beta-Peptides/metabolism
Czasopismo naukowe
Tytuł:
N, N-Dimethyltryptamine, a natural hallucinogen, ameliorates Alzheimer's disease by restoring neuronal Sigma-1 receptor-mediated endoplasmic reticulum-mitochondria crosstalk.
Autorzy:
Cheng D; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital (HKU-SZH), Shenzhen, China.; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Lei ZG; Department of Neuroscience, City University of Hong Kong, Hong Kong, China.
Chu K; Department of Psychology, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China.
Lam OJH; School of Biomedical Sciences, Faculty of Science, The University of Hong Kong, Hong Kong, China.
Chiang CY; Digital Centre of State Key Laboratory of Quality Research in Chinese Medicine, Macau, China.
Zhang ZJ; Department of Chinese Medicine, The University of Hong Kong-Shenzhen Hospital (HKU-SZH), Shenzhen, China. .; School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China. .
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Źródło:
Alzheimer's research & therapy [Alzheimers Res Ther] 2024 May 01; Vol. 16 (1), pp. 95. Date of Electronic Publication: 2024 May 01.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Receptors, sigma*/metabolism
Receptors, sigma*/agonists
Sigma-1 Receptor*
Alzheimer Disease*/metabolism
Alzheimer Disease*/drug therapy
Alzheimer Disease*/pathology
Endoplasmic Reticulum*/drug effects
Endoplasmic Reticulum*/metabolism
Mice, Transgenic*
Mitochondria*/drug effects
Mitochondria*/metabolism
Hallucinogens*/pharmacology
N,N-Dimethyltryptamine*/pharmacology
Animals ; Mice ; Neurons/drug effects ; Neurons/metabolism ; Male
Czasopismo naukowe
Tytuł:
Anti-inflammatory role of APRIL by modulating regulatory B cells in antigen-induced arthritis.
Autorzy:
Carvalho-Santos A; Laboratory on Thymus Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; Experimental Pathology Laboratory, Department of Immunobiology, Biology Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Ballard Kuhnert LR; Experimental Pathology Laboratory, Department of Immunobiology, Biology Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Hahne M; Institut de Génétique Moléculaire de Montpellier, Université de Montpellier, CNRS, Label 'Equipe FRM', Montpellier, France.
Vasconcellos R; Experimental Pathology Laboratory, Department of Immunobiology, Biology Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Carvalho-Pinto CE; Experimental Pathology Laboratory, Department of Immunobiology, Biology Institute, Fluminense Federal University, Niterói, RJ, Brazil.
Villa-Verde DMS; Laboratory on Thymus Research, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; National Institute of Science and Technology on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; Rio de Janeiro Research Network on Neuroinflammation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.; INOVA-IOC Network on Neuroimmunomodulation, Oswaldo Cruz Institute, Oswaldo Cruz Foundation, Rio de Janeiro, RJ, Brazil.
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Źródło:
PloS one [PLoS One] 2024 May 01; Vol. 19 (5), pp. e0292028. Date of Electronic Publication: 2024 May 01 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Arthritis, Experimental*/immunology
Arthritis, Experimental*/pathology
B-Lymphocytes, Regulatory*/immunology
Mice, Transgenic*
Tumor Necrosis Factor Ligand Superfamily Member 13*/metabolism
Tumor Necrosis Factor Ligand Superfamily Member 13*/genetics
Animals ; Mice ; Interleukin-10/metabolism ; Lymph Nodes/immunology ; Lymph Nodes/pathology ; Spleen/immunology
Czasopismo naukowe
Tytuł:
L-DOPA regulates neuroinflammation and Aβ pathology through NEP and ADAM17 in a mouse model of AD.
Autorzy:
Lee HJ; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.
Nam J; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.
Hwang JW; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.
Park JH; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.; Department of Brain & Cognitive Sciences, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu, 42988, Korea.
Jeong YJ; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.; Department of Brain & Cognitive Sciences, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu, 42988, Korea.
Jang JY; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.; Department of Brain & Cognitive Sciences, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu, 42988, Korea.
Kim SJ; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.
Jo AR; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea.
Hoe HS; Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), 61, Cheomdan-Ro, Dong-Gu, Daegu, 41068, Korea. .; Department of Brain & Cognitive Sciences, Daegu Gyeongbuk Institute of Science & Technology (DGIST), Daegu, 42988, Korea. .
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Źródło:
Molecular brain [Mol Brain] 2024 Apr 30; Vol. 17 (1), pp. 21. Date of Electronic Publication: 2024 Apr 30.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Levodopa*/pharmacology
Alzheimer Disease*/pathology
Alzheimer Disease*/drug therapy
Alzheimer Disease*/metabolism
Disease Models, Animal*
ADAM17 Protein*/metabolism
Amyloid beta-Peptides*/metabolism
tau Proteins*/metabolism
Neuroinflammatory Diseases*/drug therapy
Neuroinflammatory Diseases*/pathology
Neuroinflammatory Diseases*/metabolism
Mice, Transgenic*
Animals ; Phosphorylation/drug effects ; Plaque, Amyloid/pathology ; Plaque, Amyloid/metabolism ; Mice ; Brain/pathology ; Brain/drug effects ; Brain/metabolism
Czasopismo naukowe
Tytuł:
Subregion preference in the long-range connectome of pyramidal neurons in the medial prefrontal cortex.
Autorzy:
Tudi A; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Yao M; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Tang F; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Zhou J; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.
Li A; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, China.
Gong H; Britton Chance Center for Biomedical Photonics, Wuhan National Laboratory for Optoelectronics, MoE Key Laboratory for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, China.
Jiang T; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, China. .
Li X; HUST-Suzhou Institute for Brainsmatics, JITRI, Suzhou, China. .; State Key Laboratory of Digital Medical Engineering, School of Biomedical Engineering, Hainan University, Haikou, China. .
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Źródło:
BMC biology [BMC Biol] 2024 Apr 29; Vol. 22 (1), pp. 95. Date of Electronic Publication: 2024 Apr 29.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Prefrontal Cortex*/physiology
Prefrontal Cortex*/cytology
Pyramidal Cells*/physiology
Mice, Transgenic*
Connectome*
Animals ; Mice ; Male
Czasopismo naukowe
Tytuł:
Effect of SARS-CoV-2 S protein on the proteolytic cleavage of the epithelial Na+ channel ENaC.
Autorzy:
Magaña-Ávila GR; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Moreno E; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Plata C; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Carbajal-Contreras H; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Facultad de Medicina, PECEM (MD/PhD), Universidad Nacional Autónoma de México, Mexico City, Mexico.
Murillo-de-Ozores AR; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Facultad de Medicina, Universidad Nacional Autónoma de México, Mexico City, Mexico.
García-Ávila K; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
Vázquez N; Instituto de Investigaciones Biomédicas, Molecular Physiology Unit, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Syed M; Department of Medicine, Division of Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Wysocki J; Department of Medicine, Division of Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Batlle D; Department of Medicine, Division of Nephrology and Hypertension, Northwestern University Feinberg School of Medicine, Chicago, IL, United States of America.
Gamba G; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.; Facultad de Medicina, PECEM (MD/PhD), Universidad Nacional Autónoma de México, Mexico City, Mexico.; Instituto de Investigaciones Biomédicas, Molecular Physiology Unit, Universidad Nacional Autónoma de México, Mexico City, Mexico.
Castañeda-Bueno M; Department of Nephrology and Mineral Metabolism, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico.
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Źródło:
PloS one [PLoS One] 2024 Apr 25; Vol. 19 (4), pp. e0302436. Date of Electronic Publication: 2024 Apr 25 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Epithelial Sodium Channels*/metabolism
Furin*/metabolism
SARS-CoV-2*/metabolism
SARS-CoV-2*/pathogenicity
Proteolysis*
Spike Glycoprotein, Coronavirus*/metabolism
COVID-19*/metabolism
COVID-19*/virology
Mice, Transgenic*
Animals ; Humans ; Mice ; Alveolar Epithelial Cells/metabolism ; Alveolar Epithelial Cells/virology ; Lung/metabolism ; Lung/virology ; Lung/pathology ; HEK293 Cells
Czasopismo naukowe
Tytuł:
Reduced Expression of CLEC4G in Neurons Is Associated with Alzheimer's Disease.
Autorzy:
Feng X; School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 510631, China.
Qi F; Department of Neurology, Mayo Clinic, Rochester, MN 55901, USA.; Department of Anatomy and Physiology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Huang Y; Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Zhang G; Department of Microbial and Biochemical Pharmacy, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Deng W; School of Pharmaceutical Sciences (Shenzhen), Shenzhen Campus of Sun Yat-sen University, Shenzhen 510631, China.
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Źródło:
International journal of molecular sciences [Int J Mol Sci] 2024 Apr 24; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 24.
Typ publikacji:
Journal Article
MeSH Terms:
Alzheimer Disease*/metabolism
Alzheimer Disease*/genetics
Alzheimer Disease*/pathology
Neurons*/metabolism
Lectins, C-Type*/metabolism
Lectins, C-Type*/genetics
Mice, Transgenic*
Animals ; Mice ; Humans ; Brain/metabolism ; Brain/pathology ; Gene Expression Regulation ; Disease Models, Animal
Czasopismo naukowe
Tytuł:
Chemogenetic Manipulation of Amygdala Kappa Opioid Receptor Neurons Modulates Amygdala Neuronal Activity and Neuropathic Pain Behaviors.
Autorzy:
Ji G; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Presto P; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Kiritoshi T; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.
Chen Y; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
Navratilova E; Department of Pharmacology, Arizona Health Sciences Center, University of Arizona, Tucson, AZ 85721, USA.
Porreca F; Department of Pharmacology, Arizona Health Sciences Center, University of Arizona, Tucson, AZ 85721, USA.
Neugebauer V; Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St., Lubbock, TX 79430, USA.; Center of Excellence for Translational Neuroscience and Therapeutics, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.; Garrison Institute on Aging, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USA.
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Źródło:
Cells [Cells] 2024 Apr 19; Vol. 13 (8). Date of Electronic Publication: 2024 Apr 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Receptors, Opioid, kappa*/metabolism
Receptors, Opioid, kappa*/genetics
Neuralgia*/metabolism
Neuralgia*/physiopathology
Neurons*/metabolism
Amygdala*/metabolism
Mice, Transgenic*
Animals ; Mice ; Behavior, Animal ; Male ; Clozapine/analogs & derivatives ; Clozapine/pharmacology ; Central Amygdaloid Nucleus/metabolism
Czasopismo naukowe
Tytuł:
Endothelial EGLN3-PKM2 signaling induces the formation of acute astrocytic barrier to alleviate immune cell infiltration after subarachnoid hemorrhage.
Autorzy:
Duan M; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Ru X; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Zhou J; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Department of Neurosurgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, China.
Li Y; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Guo P; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Kang W; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Li W; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Chen Z; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China.; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China.
Feng H; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China. .; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .
Chen Y; Department of Neurosurgery and State Key Laboratory of Trauma, Burn and Combined Injury, Southwest Hospital, Third Military Medical University (Army Medical University), 29 Gaotanyan Street, Shapingba District, Chongqing, 400038, China. .; Chongqing Key Laboratory of Intelligent Diagnosis, Treatment and Rehabilitation of Central Nervous System Injuries, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .; Chongqing Clinical Research Center for Neurosurgery, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, 400038, China. .
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Źródło:
Fluids and barriers of the CNS [Fluids Barriers CNS] 2024 May 16; Vol. 21 (1), pp. 42. Date of Electronic Publication: 2024 May 16.
Typ publikacji:
Journal Article
MeSH Terms:
Astrocytes*/metabolism
Subarachnoid Hemorrhage*/metabolism
Subarachnoid Hemorrhage*/immunology
Signal Transduction*/physiology
Blood-Brain Barrier*/metabolism
Endothelial Cells*/metabolism
Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Male ; Pyruvate Kinase/metabolism ; Carrier Proteins/metabolism ; Brain Edema/metabolism ; Mice, Transgenic ; Membrane Proteins/metabolism
Czasopismo naukowe
Tytuł:
Sex-dependent interactions between prodromal intestinal inflammation and LRRK2 G2019S in mice promote endophenotypes of Parkinson's disease.
Autorzy:
Fang P; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. .
Yu LW; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Espey H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Agirman G; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Kazmi SA; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Li K; F. Widjaja Foundation Inflammatory Bowel & Immunobiology Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.; Research Division of Immunology, Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, 90048, USA.
Deng Y; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Lee J; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Hrncir H; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Romero-Lopez A; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA.
Arnold AP; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Hsiao EY; Department of Integrative Biology & Physiology, University of California, Los Angeles, Los Angeles, CA, 90095, USA. .; UCLA Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, 90095, USA. .; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. .
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Źródło:
Communications biology [Commun Biol] 2024 May 15; Vol. 7 (1), pp. 570. Date of Electronic Publication: 2024 May 15.
Typ publikacji:
Journal Article
MeSH Terms:
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/genetics
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2*/metabolism
Parkinson Disease*/genetics
Parkinson Disease*/metabolism
Parkinson Disease*/pathology
Animals ; Mice ; Male ; Female ; Endophenotypes ; alpha-Synuclein/metabolism ; alpha-Synuclein/genetics ; Prodromal Symptoms ; Disease Models, Animal ; Mice, Transgenic ; Humans ; Sex Factors ; Inflammation/metabolism ; Inflammation/genetics ; Mice, Inbred C57BL ; Sex Characteristics
Czasopismo naukowe
Tytuł:
Effects of Nox4 upregulation on PECAM-1 expression in a mouse model of diabetic retinopathy.
Autorzy:
Wang J; Department of Ophthalmology and Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America.
Lai DA; Department of Ophthalmology and Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America.
Wang JJ; Department of Ophthalmology and Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America.
Zhang SX; Department of Ophthalmology and Ross Eye Institute, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America.; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, NY, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 15; Vol. 19 (5), pp. e0303010. Date of Electronic Publication: 2024 May 15 (Print Publication: 2024).
Typ publikacji:
Journal Article
MeSH Terms:
NADPH Oxidase 4*/metabolism
NADPH Oxidase 4*/genetics
Diabetic Retinopathy*/metabolism
Diabetic Retinopathy*/genetics
Diabetic Retinopathy*/pathology
Up-Regulation*
Platelet Endothelial Cell Adhesion Molecule-1*/metabolism
Platelet Endothelial Cell Adhesion Molecule-1*/genetics
Endothelial Cells*/metabolism
Animals ; Mice ; Humans ; Mice, Knockout ; NADPH Oxidases/metabolism ; NADPH Oxidases/genetics ; Retina/metabolism ; Retina/pathology ; Disease Models, Animal ; Mice, Transgenic
Czasopismo naukowe
Tytuł:
The uterine secretome initiates growth of gynecologic tissues in ectopic locations.
Autorzy:
Sunde J; Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, WA, United States of America.; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX, United States of America.; Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston TX, United States of America.
Wasickanin M; Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, WA, United States of America.
Katz TA; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX, United States of America.
Gillette L; Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, WA, United States of America.
Bidadi S; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX, United States of America.
O'Neil D; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX, United States of America.
Masand R; Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston TX, United States of America.; Department of Pathology and Immunology, Baylor College of Medicine, Houston TX, United States of America.
Burney RO; Department of Obstetrics and Gynecology, Madigan Army Medical Center, Tacoma, WA, United States of America.; Department of Clinical Investigation, Madigan Army Medical Center, Tacoma, WA, United States of America.; Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Pennington KA; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Baylor College of Medicine, Houston, TX, United States of America.; Department of Obstetrics and Gynecology, Basic Sciences Perinatology Research Laboratories, Baylor College of Medicine, Houston, TX, United States of America.
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Źródło:
PloS one [PLoS One] 2024 May 10; Vol. 19 (5), pp. e0292978. Date of Electronic Publication: 2024 May 10 (Print Publication: 2024).
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Endometriosis*/metabolism
Endometriosis*/pathology
Endometriosis*/genetics
Uterus*/metabolism
Endometrium*/metabolism
Animals ; Female ; Mice ; Leukemia Inhibitory Factor/metabolism ; Leukemia Inhibitory Factor/genetics ; Secretome/metabolism ; Mice, Transgenic ; Disease Models, Animal ; Fallopian Tubes/metabolism ; Progesterone/metabolism ; Mice, Knockout ; Embryo Implantation/physiology
Czasopismo naukowe

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