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Wyszukujesz frazę ""Mice, Transgenic"" wg kryterium: Temat


Tytuł :
Novel hepatitis B virus infection mouse model using herpes simplex virus type 1 thymidine kinase transgenic mice.
Autorzy :
Kanbe A; Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu City, Japan.
Ishikawa T; Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Hara A; Department of Tumor Pathology, Gifu University Graduate School of Medicine, Gifu City, Japan.
Suemizu H; Department of Laboratory Animal Research, Central Institute for Experimental Animals, Kawasaki, Japan.
Nanizawa E; Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Tamaki Y; Department of Radiological and Medical Laboratory Sciences, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Ito H; Department of Informative Clinical Medicine, Gifu University Graduate School of Medicine, Gifu City, Japan.
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Źródło :
Journal of gastroenterology and hepatology [J Gastroenterol Hepatol] 2021 Mar; Vol. 36 (3), pp. 782-789. Date of Electronic Publication: 2020 Jul 07.
Typ publikacji :
Journal Article
MeSH Terms :
Disease Models, Animal*
Hepatitis B, Chronic*/immunology
Mice, Transgenic*
Herpesvirus 1, Human/*enzymology
Thymidine Kinase/*genetics
Animals ; Ganciclovir/administration & dosage ; Hepatitis B Surface Antigens ; Hepatocytes/transplantation ; Injections, Intraperitoneal ; Interferon-gamma/metabolism ; Liver/immunology
Czasopismo naukowe
Tytuł :
Intermittent Hypoxic Conditioning Rescues Cognition and Mitochondrial Bioenergetic Profile in the Triple Transgenic Mouse Model of Alzheimer's Disease.
Autorzy :
Correia SC; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-504 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Institute for Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal.
Machado NJ; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-504 Coimbra, Portugal.
Alves MG; Unit for Multidisciplinary Research in Biomedicine (UMIB), Department of Anatomy, Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, 4050-313 Porto, Portugal.
Oliveira PF; QOPNA & LAQV, Department of Chemistry, University of Aveiro, 3810-193 Aveiro, Portugal.
Moreira PI; Center for Neuroscience and Cell Biology (CNC), University of Coimbra, 3004-504 Coimbra, Portugal.; Center for Innovative Biomedicine and Biotechnology (CIBB), University of Coimbra, 3004-504 Coimbra, Portugal.; Laboratory of Physiology, Faculty of Medicine, University of Coimbra, 3000-548 Coimbra, Portugal.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jan 05; Vol. 22 (1). Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
Alzheimer Disease/*physiopathology
Cognition/*physiology
Cognition Disorders/*physiopathology
Energy Metabolism/*physiology
Hypoxia/*physiopathology
Mice, Transgenic/*physiology
Mitochondria/*physiology
Alzheimer Disease/metabolism ; Amyloid beta-Peptides/metabolism ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Anxiety/metabolism ; Anxiety/physiopathology ; Brain/metabolism ; Brain/physiopathology ; Cognition Disorders/metabolism ; Disease Models, Animal ; Hypoxia/metabolism ; Male ; Mice ; Mice, Transgenic/metabolism ; Mitochondria/metabolism
Czasopismo naukowe
Tytuł :
A Genetically Engineered Mouse Model of Malignant Testicular Germ Cell Tumors.
Autorzy :
Lyndaker AM; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.; Division of Mathematics and Natural Sciences, Elmira College, Elmira, NY, USA.
Pierpont TM; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Loehr AR; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.
Weiss RS; Department of Biomedical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2195, pp. 147-165.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Neoplasms, Germ Cell and Embryonal/*etiology
Neoplasms, Germ Cell and Embryonal/*pathology
Testicular Neoplasms/*etiology
Testicular Neoplasms/*pathology
Alleles ; Animals ; Antineoplastic Agents/pharmacology ; Biomarkers, Tumor ; Breeding ; Cell Line, Tumor ; Genetic Engineering ; Genotype ; Humans ; Male ; Mice ; Neoplasms, Germ Cell and Embryonal/drug therapy ; Testicular Neoplasms/drug therapy ; Xenograft Model Antitumor Assays
SCR Disease Name :
Testicular Germ Cell Tumor
Czasopismo naukowe
Tytuł :
Genetically Engineered Mouse Model in Ewing Sarcoma.
Autorzy :
Tanaka M; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan.
Nakamura T; Division of Carcinogenesis, The Cancer Institute, Japanese Foundation for Cancer Research, Tokyo, Japan. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2226, pp. 183-189.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Bone Neoplasms/*genetics
Bone Neoplasms/*pathology
Sarcoma, Ewing/*genetics
Sarcoma, Ewing/*pathology
Animals ; Biomarkers, Tumor ; Biopsy ; Cell Line, Tumor ; Humans ; Mice ; Oncogene Proteins, Fusion ; Proto-Oncogene Protein c-fli-1 ; RNA-Binding Protein EWS
Czasopismo naukowe
Tytuł :
Advances in Transgenic Mouse Models to Study Infections by Human Pathogenic Viruses.
Autorzy :
Masemann D; Institute of Virology Muenster, University of Muenster, 48149 Muenster, Germany.
Ludwig S; Institute of Virology Muenster, University of Muenster, 48149 Muenster, Germany.
Boergeling Y; Institute of Virology Muenster, University of Muenster, 48149 Muenster, Germany.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2020 Dec 05; Vol. 21 (23). Date of Electronic Publication: 2020 Dec 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Virus Diseases/*etiology
Animals ; Gene Expression Regulation, Viral ; Host-Pathogen Interactions ; Humans ; Immune System ; Organ Specificity ; Receptors, Cell Surface/metabolism ; Viral Tropism ; Virus Diseases/diagnosis ; Virus Diseases/therapy ; Virus Replication
Czasopismo naukowe
Tytuł :
HLA transgenic mice: application in reproducing idiosyncratic drug toxicity.
Autorzy :
Susukida T; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.; Laboratory of Cancer Biology and Immunology, Section of Host Defenses, Institute of Natural Medicine, University of Toyama, Toyama, Japan.
Aoki S; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Shirayanagi T; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Yamada Y; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Kuwahara S; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
Ito K; Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chiba, Japan.
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Źródło :
Drug metabolism reviews [Drug Metab Rev] 2020 Nov; Vol. 52 (4), pp. 540-567. Date of Electronic Publication: 2020 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Disease Models, Animal*
Mice, Transgenic*
Antiviral Agents/*toxicity
HLA Antigens/*genetics
Virus Diseases/*drug therapy
Alleles ; Animals ; Antiviral Agents/therapeutic use ; Dideoxynucleosides/therapeutic use ; Dideoxynucleosides/toxicity ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Mice
Czasopismo naukowe
Tytuł :
Brain-specific PAPP-A knock-out mice?
Autorzy :
Bale LK; Division of Endocrinology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States of America.
West SA; Division of Endocrinology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States of America.
Conover CA; Division of Endocrinology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, United States of America. Electronic address: .
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Źródło :
Experimental gerontology [Exp Gerontol] 2021 Oct 15; Vol. 154, pp. 111548. Date of Electronic Publication: 2021 Sep 09.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Longevity*
Pregnancy-Associated Plasma Protein-A*/genetics
Animals ; Brain/metabolism ; Female ; Genotype ; Mice ; Mice, Knockout ; Mice, Transgenic ; Pregnancy
Czasopismo naukowe
Tytuł :
Tetraspanin TM4SF5 in hepatocytes negatively modulates SLC27A transporters during acute fatty acid supply.
Autorzy :
Park D; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Kim E; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee H; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Shin EA; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee H; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea.
Lee JW; Department of Pharmacy, Research Institute of Pharmaceutical Sciences, College of Pharmacy, Seoul National University, Seoul, 08826, South Korea. Electronic address: .
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Źródło :
Archives of biochemistry and biophysics [Arch Biochem Biophys] 2021 Oct 15; Vol. 710, pp. 109004. Date of Electronic Publication: 2021 Aug 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Fatty Acid Transport Proteins/*metabolism
Fatty Acids/*metabolism
Hepatocytes/*metabolism
Membrane Proteins/*metabolism
Animals ; Biological Transport, Active ; Cell Line ; Energy Metabolism ; Fatty Acid Transport Proteins/antagonists & inhibitors ; Fatty Acid Transport Proteins/genetics ; HEK293 Cells ; Hep G2 Cells ; Humans ; Membrane Proteins/antagonists & inhibitors ; Membrane Proteins/deficiency ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mice, Transgenic ; Models, Biological ; Non-alcoholic Fatty Liver Disease/etiology ; Non-alcoholic Fatty Liver Disease/metabolism ; Oxygen Consumption ; RNA, Small Interfering/genetics
Czasopismo naukowe
Tytuł :
Isoform-Specific Reduction of the Basic Helix-Loop-Helix Transcription Factor TCF4 Levels in Huntington's Disease.
Autorzy :
Nurm K; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia.
Sepp M; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia.
Castany-Pladevall C; Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia 08036, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia 08036, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, 28031, Spain.
Creus-Muncunill J; Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia 08036, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia 08036, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, 28031, Spain.
Tuvikene J; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia.; Protobios LLC, Tallinn 12618, Estonia.
Sirp A; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia.
Vihma H; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia.
Blake DJ; Division of Psychological Medicine and Clinical Neurosciences, MRC Centre for Neuropsychiatric Genetics and Genomics, Cardiff University, Cardiff CF24 4HQ, United Kingdom.
Perez-Navarro E; Departament de Biomedicina, Facultat de Medicina i Ciències de la Salut, Institut de Neurociències, Universitat de Barcelona, Barcelona, Catalonia 08036, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Catalonia 08036, Spain.; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, 28031, Spain.
Timmusk T; Department of Chemistry and Biotechnology, Tallinn University of Technology, Tallinn 12618, Estonia .; Protobios LLC, Tallinn 12618, Estonia.
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Źródło :
ENeuro [eNeuro] 2021 Oct 14; Vol. 8 (5). Date of Electronic Publication: 2021 Oct 14 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Huntington Disease*/genetics
Adult ; Animals ; Disease Models, Animal ; Hippocampus ; Humans ; Male ; Mice ; Mice, Transgenic ; Neurons ; Protein Isoforms ; Transcription Factor 4/genetics
Czasopismo naukowe
Tytuł :
Analysis of SARS-CoV-2 infection dynamic in vivo using reporter-expressing viruses.
Autorzy :
Ye C; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227; .; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Chiem K; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Park JG; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Silvas JA; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Morales Vasquez D; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Sourimant J; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Lin MJ; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA 98195.
Greninger AL; Virology Division, Department of Laboratory Medicine, University of Washington, Seattle, WA 98195.
Plemper RK; Center for Translational Antiviral Research, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303.
Torrelles JB; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227.; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
Kobie JJ; Department of Medicine, Division of Infectious Diseases, University of Alabama at Birmingham, Birmingham, AL 35294.
Walter MR; Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294.
de la Torre JC; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037.
Martinez-Sobrido L; Host-Pathogen Interactions Program, Texas Biomedical Research Institute, San Antonio, TX 78227; .; Population Health Program, Texas Biomedical Research Institute, San Antonio, TX 78227.
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Oct 12; Vol. 118 (41).
Typ publikacji :
Journal Article
MeSH Terms :
COVID-19*/genetics
COVID-19*/metabolism
Gene Expression Regulation, Viral*
Genes, Reporter*
SARS-CoV-2*/genetics
SARS-CoV-2*/metabolism
Viral Proteins*/biosynthesis
Viral Proteins*/genetics
Angiotensin-Converting Enzyme 2/genetics ; Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Chlorocebus aethiops ; Coronavirus Nucleocapsid Proteins/biosynthesis ; Coronavirus Nucleocapsid Proteins/genetics ; Female ; Humans ; Mice ; Mice, Transgenic ; Teschovirus/genetics ; Vero Cells
Czasopismo naukowe
Tytuł :
APOE4 genotype exacerbates the depression-like behavior of mice during aging through ATP decline.
Autorzy :
Fang W; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China.; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Xiao N; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China.; Department of Neurology, The First Affiliated Hospital of Xiamen University, 55 Zhenhai Road, Xiamen, Fujian, 361003, China.
Zeng G; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Bi D; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China.; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Dai X; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China.; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Mi X; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Ye Q; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China.; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China.
Chen X; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China. .; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China. .
Zhang J; Department of Neurology and Geriatrics, Fujian Institute of Geriatrics, Fujian Medical University Union Hospital, 29 Xinquan Road, Fuzhou, Fujian, 350001, China. .; Fujian Key Laboratory of Molecular Neurology, Institute of Neuroscience, Fujian Medical University, 88 Jiaotong Road, Fuzhou, Fujian, 350005, China. .
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Źródło :
Translational psychiatry [Transl Psychiatry] 2021 Oct 05; Vol. 11 (1), pp. 507. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Apolipoprotein E4*/genetics
Depression*/genetics
Adenosine Triphosphate ; Aged ; Animals ; Genotype ; Humans ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Increased lethality in influenza and SARS-CoV-2 coinfection is prevented by influenza immunity but not SARS-CoV-2 immunity.
Autorzy :
Achdout H; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Vitner EB; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Politi B; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Melamed S; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Yahalom-Ronen Y; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Tamir H; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Erez N; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Avraham R; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Weiss S; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Cherry L; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Bar-Haim E; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Makdasi E; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Gur D; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Aftalion M; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Chitlaru T; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Vagima Y; Department of Biochemistry and Molecular Genetics, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Paran N; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel.
Israely T; Departments of Infectious Diseases, Israel Institute for Biological Research, Ness-Ziona, 7410001, Israel. .
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Źródło :
Nature communications [Nat Commun] 2021 Oct 05; Vol. 12 (1), pp. 5819. Date of Electronic Publication: 2021 Oct 05.
Typ publikacji :
Journal Article
MeSH Terms :
Immunity*
COVID-19/*immunology
COVID-19/*virology
Coinfection/*immunology
Coinfection/*virology
Orthomyxoviridae Infections/*immunology
Orthomyxoviridae Infections/*virology
SARS-CoV-2/*immunology
Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antibodies, Viral/immunology ; COVID-19/pathology ; Cell Line ; Disease Models, Animal ; Female ; Humans ; Inflammation/genetics ; Lung/pathology ; Lung/virology ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Up-Regulation/genetics ; Viral Load/immunology
Czasopismo naukowe
Tytuł :
Measuring Amyloid-β Peptide Concentrations in Murine Brain with Improved ELISA Assay.
Autorzy :
Peng HB; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.
de Lannoy IAM; InterVivo Solutions Inc., Mississauga, Ontario, Canada.
Pang KS; Department of Pharmaceutical Sciences, Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Ontario, Canada.
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Źródło :
Current protocols [Curr Protoc] 2021 Oct; Vol. 1 (10), pp. e253.
Typ publikacji :
Journal Article
MeSH Terms :
Amyloid beta-Peptides*/metabolism
Plaque, Amyloid*
Animals ; Brain/metabolism ; Enzyme-Linked Immunosorbent Assay ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Potential for transmission of sporadic Creutzfeldt-Jakob disease through peripheral routes.
Autorzy :
Kobayashi A; Laboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan. .
Munesue Y; Laboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Shimazaki T; Laboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Aoshima K; Laboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Kimura T; Laboratory of Comparative Pathology, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
Mohri S; Division of Neurological Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
Kitamoto T; Division of Neurological Science, Tohoku University Graduate School of Medicine, Sendai, Japan.
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Źródło :
Laboratory investigation; a journal of technical methods and pathology [Lab Invest] 2021 Oct; Vol. 101 (10), pp. 1327-1330. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Creutzfeldt-Jakob Syndrome/*metabolism
Creutzfeldt-Jakob Syndrome/*transmission
Animals ; Brain Chemistry ; Creutzfeldt-Jakob Syndrome/classification ; Humans ; Mice ; Mice, Transgenic ; PrPC Proteins/chemistry ; PrPC Proteins/genetics ; PrPC Proteins/metabolism
SCR Disease Name :
Creutzfeldt-Jakob Disease, Sporadic
Czasopismo naukowe
Tytuł :
Maternal fish oil consumption has a negative impact on mammary gland tumorigenesis in C3(1) Tag mice offspring.
Autorzy :
Ion G; Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, WV, USA. .; Ştefan S. Nicolau Institute of Virology, Center of Immunology, Bucuresti, Romania. .
Akinsete JA; Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, WV, USA.; Kentucky Christian University, Grayson, KY, USA.
Witte TR; Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, WV, USA.
Bostan M; Ştefan S. Nicolau Institute of Virology, Center of Immunology, Bucuresti, Romania. .
Hardman WE; Joan C. Edwards School of Medicine, Department of Biomedical Sciences, Marshall University, Huntington, WV, USA.
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Źródło :
European journal of nutrition [Eur J Nutr] 2021 Oct; Vol. 60 (7), pp. 3771-3781. Date of Electronic Publication: 2021 Apr 04.
Typ publikacji :
Journal Article
MeSH Terms :
Fatty Acids, Omega-3*
Fish Oils*
Animals ; Carcinogenesis ; Corn Oil ; Female ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Sensory Neuron TLR4 mediates the development of nerve-injury induced mechanical hypersensitivity in female mice.
Autorzy :
Szabo-Pardi TA; Neuroimmunology and Behavior Group, Department of Neuroscience, Center for Advanced Pain Studies (CAPS), School of Behavioral and Brain Sciences, University of Texas at Dallas. 800 W. Campbell Rd. Richardson, TX 75080, USA.
Barron LR; Neuroimmunology and Behavior Group, Department of Neuroscience, Center for Advanced Pain Studies (CAPS), School of Behavioral and Brain Sciences, University of Texas at Dallas. 800 W. Campbell Rd. Richardson, TX 75080, USA.
Lenert ME; Neuroimmunology and Behavior Group, Department of Neuroscience, Center for Advanced Pain Studies (CAPS), School of Behavioral and Brain Sciences, University of Texas at Dallas. 800 W. Campbell Rd. Richardson, TX 75080, USA.
Burton MD; Neuroimmunology and Behavior Group, Department of Neuroscience, Center for Advanced Pain Studies (CAPS), School of Behavioral and Brain Sciences, University of Texas at Dallas. 800 W. Campbell Rd. Richardson, TX 75080, USA. Electronic address: .
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Źródło :
Brain, behavior, and immunity [Brain Behav Immun] 2021 Oct; Vol. 97, pp. 42-60. Date of Electronic Publication: 2021 Jun 23.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Hyperalgesia*
Neuralgia*
Toll-Like Receptor 4*/genetics
Animals ; Female ; Male ; Mice ; Mice, Transgenic ; Sensory Receptor Cells
Czasopismo naukowe
Tytuł :
Mesenchymal stromal cells expressing a dominant-negative high mobility group A1 transgene exhibit improved function during sepsis.
Autorzy :
Kwon MY; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ghanta S; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ng J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Castano AP; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Han J; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ith B; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Lederer JA; Department of Surgery, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
El-Chemaly S; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Chung SW; Department of Biological Sciences, University of Ulsan, Ulsan, South Korea.
Liu X; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Perrella MA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Pediatric Newborn Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
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Źródło :
Journal of leukocyte biology [J Leukoc Biol] 2021 Oct; Vol. 110 (4), pp. 711-722. Date of Electronic Publication: 2021 Jan 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Genes, Dominant*
Mesenchymal Stem Cell Transplantation*
Transgenes*
HMGA1a Protein/*genetics
Mesenchymal Stem Cells/*metabolism
Sepsis/*pathology
Sepsis/*therapy
Adipocytes/cytology ; Animals ; Cell Death ; Cell Proliferation ; Cell Survival ; Chemokine CXCL12/biosynthesis ; Escherichia coli/physiology ; HMGA1a Protein/metabolism ; Inflammation/pathology ; Interleukin-6/biosynthesis ; Male ; Mice, Inbred C57BL ; Mice, Transgenic ; Neutrophil Infiltration ; Neutrophils/metabolism ; Oxidative Stress ; Phagocytosis ; Sepsis/microbiology
Czasopismo naukowe
Tytuł :
Effect of involuntary chronic physical exercise on beta-amyloid protein in experimental models of Alzheimer's disease: Systematic review and meta-analysis.
Autorzy :
Vasconcelos-Filho FSL; Pró-reitoria de Cultura, Universidade Federal do Cariri, Juazeiro do Norte, Ceará, Brazil; Laboratório de Bioquímica e Expressão Gênica, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil. Electronic address: .
da Rocha Oliveira LC; Departamento de Ciências da Saúde, Faculdade de Medicina, Universidade Federal Rural do Semi-árido, Mossoró, Rio Grande do Norte, Brazil.
de Freitas TBC; Departamento de Ciências da Saúde, Faculdade de Medicina, Universidade Federal Rural do Semi-árido, Mossoró, Rio Grande do Norte, Brazil.
de Pontes PADS; Departamento de Ciências da Saúde, Faculdade de Medicina, Universidade Federal Rural do Semi-árido, Mossoró, Rio Grande do Norte, Brazil.
Rocha-E-Silva RCD; Faculdade de Medicina Veterinária, Centro Universitário de Juazeiro do Norte, Juazeiro do Norte, Ceará, Brazil.
Godinho WDN; Laboratório de Bioquímica e Expressão Gênica, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil.
Chaves EMC; Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil.
da Silva CGL; Faculdade de Medicina, Universidade Federal do Cariri, Juazeiro do Norte, Ceará, Brazil.
Soares PM; Laboratório de Bioquímica e Expressão Gênica, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil.
Ceccatto VM; Laboratório de Bioquímica e Expressão Gênica, Instituto Superior de Ciências Biomédicas, Universidade Estadual do Ceará, Fortaleza, Ceará, Brazil.
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Źródło :
Experimental gerontology [Exp Gerontol] 2021 Oct 01; Vol. 153, pp. 111502. Date of Electronic Publication: 2021 Jul 31.
Typ publikacji :
Journal Article; Meta-Analysis; Research Support, Non-U.S. Gov't; Review; Systematic Review
MeSH Terms :
Alzheimer Disease*/therapy
Amyloid beta-Peptides*
Amyloid beta-Protein Precursor ; Animals ; Disease Models, Animal ; Exercise ; Female ; Mice ; Mice, Transgenic ; Models, Theoretical ; Plaque, Amyloid
Czasopismo naukowe
Tytuł :
Comet Assay Evaluation of Lanthanum Nitrate DNA Damage in C57-ras Transgenic Mice.
Autorzy :
Han G; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Tan Z; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.
Jing H; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Ning J; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Li Z; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China.
Gao S; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China.
Li G; Institute of Toxicology, Beijing Center for Disease Prevention and Control/Beijing Research Center for Preventive Medicine/Beijing Key Laboratory of Diagnostic and Traceablity Technologies for Food Poisoning, No. 16, Hepingli Middle Street, Dongcheng District, Beijing, 100013, China. .; School of Public Health, Capital Medical University, No. 10, West Toutiao, Youanmenwai, Fengtai District, Beijing, 100069, China. .
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Źródło :
Biological trace element research [Biol Trace Elem Res] 2021 Oct; Vol. 199 (10), pp. 3728-3736. Date of Electronic Publication: 2021 Jan 05.
Typ publikacji :
Journal Article
MeSH Terms :
DNA Damage*
Lanthanum*/toxicity
Animals ; Comet Assay ; Humans ; Mice ; Mice, Transgenic
Czasopismo naukowe
Tytuł :
Chronic Exposure to Hypoxia Inhibits Myelinogenesis and Causes Motor Coordination Deficits in Adult Mice.
Autorzy :
Chen L; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Ren SY; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Li RX; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Liu K; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Chen JF; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Yang YJ; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Deng YB; Department of Neurosurgery, Chongqing Emergency Medical Center, Chongqing University, Chongqing, 400014, China.
Wang HZ; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Xiao L; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China.
Mei F; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China. .
Wang F; Department of Histology and Embryology, Chongqing Key Laboratory of Neurobiology, Brain and Intelligence Research Key Laboratory of Chongqing Education Commission, Third Military Medical University, Chongqing, 400038, China. .
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Źródło :
Neuroscience bulletin [Neurosci Bull] 2021 Oct; Vol. 37 (10), pp. 1397-1411. Date of Electronic Publication: 2021 Jul 22.
Typ publikacji :
Journal Article
MeSH Terms :
Myelin Sheath*
Oligodendroglia*
Animals ; Clemastine ; Hypoxia/complications ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic
Czasopismo naukowe

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