Temat: "Microglia" - OpacWWW

Skocz do pozycji: 1.

Tytuł:: The protective effects of EGCG was associated with HO-1 active and microglia pyroptosis inhibition in experimental intracerebral hemorrhage.
Autorzy:: Bao B; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Yin XP; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Wen XQ; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Suo YJ; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Chen ZY; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Li DL; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Lai Q; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Cao XM; Department of Neurology, The Affiliated Hospital of Jiujiang University, No.57 Xunyang East Rode, Xunyang District, Jiujiang, 332000, China.
Qu QM; Department of Neurology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China. Electronic address: .; Pokaż więcej
Źródło:: Neurochemistry international [Neurochem Int] 2023 Nov; Vol. 170, pp. 105603. Date of Electronic Publication: 2023 Aug 25.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Cerebral Hemorrhage*/drug therapy
Cerebral Hemorrhage*/genetics
Cerebral Hemorrhage*/metabolism
Heme Oxygenase-1*/genetics
Heme Oxygenase-1*/metabolism
Microglia*/drug effects
Microglia*/metabolism
Neuroinflammatory Diseases*/drug therapy
Neuroinflammatory Diseases*/metabolism
Neuroprotective Agents*/pharmacology
Neuroprotective Agents*/therapeutic use
Animals ; Mice ; Caspases/metabolism ; Caspases/pharmacology ; Cytokines/metabolism ; Interleukin-18/metabolism ; Interleukin-18/pharmacology ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Pyroptosis/drug effects ; Pyroptosis/genetics ; Antioxidants/pharmacology ; Antioxidants/therapeutic use

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Skocz do pozycji: 2.

Tytuł:: Microglia/macrophages are ultrastructurally altered by their proximity to spinal cord injury in adult female mice.
Autorzy:: St-Pierre MK; Axe Neurosciences, Centre de Recherche du CHU de Québec-Université Laval, Québec City, QC, Canada.; Department of Molecular Medicine, Université Laval, Québec City, QC, Canada.; Division of Medical Sciences, University of Victoria, 3800 Finnerty Road, Victoria, BC, V8P 5C2, Canada.
González Ibáñez F; Axe Neurosciences, Centre de Recherche du CHU de Québec-Université Laval, Québec City, QC, Canada.; Department of Molecular Medicine, Université Laval, Québec City, QC, Canada.; Division of Medical Sciences, University of Victoria, 3800 Finnerty Road, Victoria, BC, V8P 5C2, Canada.
Kroner A; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA. .; Department of Microbiology and Immunology, Medical College of Wisconsin, Milwaukee, WI, USA. .; Clement J. Zablocki Veterans Affairs Medical Center, 5000 W. National Ave, Milwaukee, WI, 53295, USA. .
Tremblay MÈ; Axe Neurosciences, Centre de Recherche du CHU de Québec-Université Laval, Québec City, QC, Canada. .; Department of Molecular Medicine, Université Laval, Québec City, QC, Canada. .; Division of Medical Sciences, University of Victoria, 3800 Finnerty Road, Victoria, BC, V8P 5C2, Canada. .; Department of Biochemistry and Molecular Biology, The University of British Columbia, Vancouver, BC, Canada. .; Department of Neurology and Neurosurgery, McGill University, Montréal, QC, Canada. .; Centre for Advanced Materials and Related Technology (CAMTEC) and Institute on Aging and Lifelong Health (IALH), University of Victoria, Victoria, BC, Canada. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2023 Nov 21; Vol. 20 (1), pp. 273. Date of Electronic Publication: 2023 Nov 21.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*/pathology
Spinal Cord Injuries*/pathology
Mice ; Female ; Animals ; Macrophages/pathology ; Phagocytes/pathology ; Spinal Cord/pathology

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 3.

Tytuł:: The effect of morphine on rat microglial phagocytic activity: An in vitro study of brain region-, plating density-, sex-, morphine concentration-, and receptor-dependency.
Autorzy:: King'uyu DN; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY 12208, United States of America. Electronic address: .
Nti-Kyemereh L; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY 12208, United States of America; Siena College, Loudonville, NY 12211, United States of America.
Bonin JL; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208, United States of America.
Feustel PJ; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY 12208, United States of America.
Tram M; Siena College, Loudonville, NY 12211, United States of America.
MacNamara KC; Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208, United States of America.
Kopec AM; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY 12208, United States of America.; Pokaż więcej
Źródło:: Journal of neuroimmunology [J Neuroimmunol] 2023 Nov 15; Vol. 384, pp. 578204. Date of Electronic Publication: 2023 Sep 21.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Morphine*/pharmacology
Microglia*/metabolism
Rats ; Male ; Female ; Animals ; Analgesics, Opioid/pharmacology ; Toll-Like Receptor 4/metabolism ; Brain/metabolism

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Skocz do pozycji: 4.

Tytuł:: Microglia Are Dispensable for Developmental Dendrite Pruning of Mitral Cells in Mice.
Autorzy:: Niiyama T; Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan.
Fujimoto S; Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan .
Imai T; Graduate School of Medical Sciences, Kyushu University, 812-8582, Fukuoka, Japan .; Pokaż więcej
Źródło:: ENeuro [eNeuro] 2023 Nov 10; Vol. 10 (11). Date of Electronic Publication: 2023 Nov 10 (Print Publication: 2023).
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Microglia*/physiology
Neurons*
Mice ; Animals ; Synapses/physiology ; Neuronal Plasticity ; Dendrites

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Skocz do pozycji: 5.

Tytuł:: Stimulation of the Pro-Resolving Receptor Fpr2 Reverses Inflammatory Microglial Activity by Suppressing NFκB Activity.
Autorzy:: Wickstead ES; Institute of Dentistry, Faculty of Medicine & Dentistry, Queen Mary University of London, Blizard Institute, 4, Newark Street, London E1 2AT, UK.; School of Life Sciences, College of Liberal Arts & Sciences, University of Westminster, 115, New Cavendish Street, London W1W 6UW, UK.; Icahn School of Medicine at Mount Sinai, Department of Neurology, Simon Hess Medical and Science Building, New York, NY 10029, USA.
Elliott BT; School of Life Sciences, College of Liberal Arts & Sciences, University of Westminster, 115, New Cavendish Street, London W1W 6UW, UK.
Pokorny S; Institute of Dentistry, Faculty of Medicine & Dentistry, Queen Mary University of London, Blizard Institute, 4, Newark Street, London E1 2AT, UK.
Biggs C; School of Life Sciences, College of Liberal Arts & Sciences, University of Westminster, 115, New Cavendish Street, London W1W 6UW, UK.
Getting SJ; School of Life Sciences, College of Liberal Arts & Sciences, University of Westminster, 115, New Cavendish Street, London W1W 6UW, UK.
McArthur S; Institute of Dentistry, Faculty of Medicine & Dentistry, Queen Mary University of London, Blizard Institute, 4, Newark Street, London E1 2AT, UK.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Nov 06; Vol. 24 (21). Date of Electronic Publication: 2023 Nov 06.
Typ publikacji:: Journal Article
MeSH Terms:: Lipopolysaccharides*/pharmacology
Microglia*/metabolism
Animals ; Mice ; Anti-Inflammatory Agents/pharmacology ; Cell Death ; NF-kappa B/metabolism

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Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 6.

Tytuł:: Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization.
Autorzy:: Yang Y; School of Basic Medical Sciences, Binzhou Medical University, Yantai, 264003, PR China.
Gao ZF; School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, PR China.
Hou GG; School of Pharmacy, The Key Laboratory of Prescription Effect and Clinical Evaluation of State Administration of Traditional Chinese Medicine of China, Binzhou Medical University, Yantai, 264003, PR China. Electronic address: .
Meng QG; School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and Biotech Drugs in Universities of Shandong, Yantai University, Yantai, 264005, People's Republic of China. Electronic address: .
Hou Y; School of Basic Medical Sciences, Binzhou Medical University, Yantai, 264003, PR China. Electronic address: .; Pokaż więcej
Źródło:: European journal of medicinal chemistry [Eur J Med Chem] 2023 Nov 05; Vol. 259, pp. 115688. Date of Electronic Publication: 2023 Jul 27.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*
Neuroinflammatory Diseases*
Mice ; Animals ; Lipopolysaccharides/pharmacology ; Lipopolysaccharides/metabolism ; Cytokines/metabolism ; Amines/pharmacology ; NF-kappa B/metabolism

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Skocz do pozycji: 7.

Tytuł:: Activation of Toll-like receptor 3 inhibits HIV infection of human iPSC-derived microglia.
Autorzy:: Wang P; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.
Liu JB; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.
Wang X; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Substance Abuse Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Meng FZ; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.
Xiao QH; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Substance Abuse Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Liu L; Center for Metabolic Disease Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Zhu J; Department of Pathology, Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Hu WH; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Metabolic Disease Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.
Ho WZ; Department of Pathology and Laboratory Medicine, Temple University LewisKatz School of Medicine, Philadelphia, Pennsylvania, USA.; Center for Substance Abuse Research, Temple University Lewis Katz School of Medicine, Philadelphia, Pennsylvania, USA.; Pokaż więcej
Źródło:: Journal of medical virology [J Med Virol] 2023 Nov; Vol. 95 (11), pp. e29217.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural
MeSH Terms:: HIV Infections*
Induced Pluripotent Stem Cells*
Microglia*/virology
Toll-Like Receptor 3*/genetics
Humans ; Cells, Cultured ; Immunity, Innate ; Poly I-C/pharmacology

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Skocz do pozycji: 8.

Tytuł:: IL-4 shapes microglia-dependent pruning of the cerebellum during postnatal development.
Autorzy:: Guedes JR; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal.
Ferreira PA; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Doctoral Program in Biosciences, Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.
Costa J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal; PDBEB-Doctoral Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Laranjo M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal; PDBEB-Doctoral Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Pinto MJ; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal.
Reis T; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal; PDBEB-Doctoral Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Cardoso AM; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal.
Lebre C; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Casquinha M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Gomes M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal; PDBEB-Doctoral Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Shkatova V; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Pereira M; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal.
Beltrão N; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal; PDBEB-Doctoral Programme in Experimental Biology and Biomedicine, Institute for Interdisciplinary Research (IIIUC), University of Coimbra, 3030-789 Coimbra, Portugal.
Hanuscheck N; University Medical Center of the Johannes Gutenberg University Mainz, Department of Neurology, 06131 Mainz, Germany.
Greenhalgh AD; Lydia Becker Institute of Immunology and Inflammation, Division of Infection, Immunity & Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester M13 9PT, UK.
Vogelaar CF; University Medical Center of the Johannes Gutenberg University Mainz, Department of Neurology, 06131 Mainz, Germany.
Carvalho AL; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal.
Zipp F; University Medical Center of the Johannes Gutenberg University Mainz, Department of Neurology, 06131 Mainz, Germany. Electronic address: .
Cardoso AL; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; IIIUC-Institute of Interdisciplinary Research, University of Coimbra, 3030-789 Coimbra, Portugal. Electronic address: .
Peça J; CNC-Center for Neuroscience and Cell Biology, University of Coimbra, 3004-504 Coimbra, Portugal; Department of Life Sciences, University of Coimbra, 3000-456 Coimbra, Portugal. Electronic address: .; Pokaż więcej
Źródło:: Neuron [Neuron] 2023 Nov 01; Vol. 111 (21), pp. 3435-3449.e8.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Interleukin-4*
Microglia*
Animals ; Humans ; Cerebellum ; Brain ; Cytokines

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Skocz do pozycji: 9.

Tytuł:: Bilirubin impacts microglial autophagy via the Akt-mTOR signaling pathway.
Autorzy:: Li L; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.; Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
Li S; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.; Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
Pan Z; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.; Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
Zhang Y; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.; Chongqing Key Laboratory of Child Infection and Immunity, Chongqing, China.
Hua Z; Department of Neonatology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing, China.; China International Science and Technology Cooperation Base of Child Development and Critical Disorders, Chongqing, China.; Pokaż więcej
Źródło:: Journal of neurochemistry [J Neurochem] 2023 Nov; Vol. 167 (4), pp. 582-599. Date of Electronic Publication: 2023 Oct 19.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*/metabolism
Kernicterus*/metabolism
Rats ; Animals ; Proto-Oncogene Proteins c-akt/metabolism ; Bilirubin/pharmacology ; Bilirubin/metabolism ; Inflammasomes/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; Neuroinflammatory Diseases ; Signal Transduction ; Autophagy/physiology ; TOR Serine-Threonine Kinases/metabolism ; Mammals/metabolism

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Skocz do pozycji: 10.

Tytuł:: Long non-coding RNA MIR17HG impedes FOSL2-mediated transcription activation of HIC1 to maintain a pro-inflammatory phenotype of microglia during intracerebral haemorrhage.
Autorzy:: Ai Y; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Kong Y; Department of Neurology, General Hospital of Northern Theater Command, Shenyang, China.
Zou Z; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Chen L; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.
Liang G; Department of Neurosurgery, General Hospital of Northern Theater Command, Shenyang, China.; Pokaż więcej
Źródło:: The European journal of neuroscience [Eur J Neurosci] 2023 Nov; Vol. 58 (10), pp. 4107-4122. Date of Electronic Publication: 2023 Oct 17.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*
RNA, Long Noncoding*/genetics
Mice ; Animals ; Transcriptional Activation ; Cerebral Hemorrhage/genetics ; Phenotype ; Lactates ; Hematoma

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Skocz do pozycji: 11.

Tytuł:: Microglia depletion ameliorates neuroinflammation, anxiety-like behavior, and cognitive deficits in a sex-specific manner in Rev-erbα knockout mice.
Autorzy:: Chen R; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA.
Routh BN; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA; Institute for Neuroscience, The University of Texas at Austin, USA.
Straetker JE; Institute for Neuroscience, The University of Texas at Austin, USA.
Gibson CR; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA; Institute for Neuroscience, The University of Texas at Austin, USA.
Weitzner AS; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA.
Bell KS; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA.
Gaudet AD; Institute for Neuroscience, The University of Texas at Austin, USA; Department of Psychology, The University of Texas at Austin, USA; Department of Neurology, Dell Medical School, The University of Texas at Austin, USA.
Fonken LK; Division of Pharmacology and Toxicology, College of Pharmacy, The University of Texas at Austin, USA; Institute for Neuroscience, The University of Texas at Austin, USA. Electronic address: .; Pokaż więcej
Źródło:: Brain, behavior, and immunity [Brain Behav Immun] 2023 Nov; Vol. 114, pp. 287-298. Date of Electronic Publication: 2023 Aug 28.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms:: Cognitive Dysfunction*/genetics
Cognitive Dysfunction*/metabolism
Microglia*/metabolism
Nuclear Receptor Subfamily 1, Group D, Member 1*/genetics
Nuclear Receptor Subfamily 1, Group D, Member 1*/metabolism
Animals ; Female ; Male ; Mice ; Anxiety ; Circadian Rhythm/physiology ; Cognition ; Mice, Knockout ; Neuroinflammatory Diseases

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Skocz do pozycji: 12.

Tytuł:: Long-term Effects of the pituitary-adenylate cyclase-activating Polypeptide (PACAP38) in the Adult Mouse Retina: Microglial Activation and Induction of Neural Proliferation.
Autorzy:: Denes V; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary. .
Lukats A; Institute of Translational Medicine, Translational Retina Research Group, Semmelweis University, Budapest, Hungary.
Szarka G; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.
Subicz R; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.
Mester A; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.
Kovacs-Valasek A; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.
Geck P; Department of Medical Education, School of Medicine, Tufts University, 136 Harrison Ave, Boston, MA, 02111, USA.
Berta G; Department of Medical Biology and Central Electron Microscope Laboratory, Medical School, University of Pécs, Pécs, Hungary.
Herczeg R; János Szentágothai Research Centre, Bioinformatics Research Group, University of Pécs, 20 Ifjúság str, Pécs, H-7624, Hungary.
Postyeni E; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.
Gyenesei A; János Szentágothai Research Centre, Bioinformatics Research Group, University of Pécs, 20 Ifjúság str, Pécs, H-7624, Hungary.
Gabriel R; Department of Neurobiology, University of Pécs, 6 Ifjúság str, Pécs, H-7624, Hungary.; Pokaż więcej
Źródło:: Neurochemical research [Neurochem Res] 2023 Nov; Vol. 48 (11), pp. 3430-3446. Date of Electronic Publication: 2023 Jul 19.
Typ publikacji:: Journal Article
MeSH Terms:: Pituitary Adenylate Cyclase-Activating Polypeptide*/pharmacology
Microglia*
Mice ; Animals ; Adenylyl Cyclases ; Endothelial Cells ; Retina

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Skocz do pozycji: 13.

Tytuł:: Sex differences in microglia function in aged rats underlie vulnerability to cognitive decline.
Autorzy:: Ince LM; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Darling JS; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Sanchez K; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Bell KS; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Melbourne JK; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Davis LK; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA; Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712, USA.
Nixon K; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA.
Gaudet AD; Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712, USA; Department of Psychology, University of Texas at Austin, Austin, TX 78712, USA; Department of Neurology, Dell Medical School, University of Texas at Austin, Austin, TX 78712, USA.
Fonken LK; Division of Pharmacology & Toxicology, College of Pharmacy, University of Texas at Austin, Austin, TX 78712, USA; Institute for Neuroscience, University of Texas at Austin, Austin, TX 78712, USA. Electronic address: .; Pokaż więcej
Źródło:: Brain, behavior, and immunity [Brain Behav Immun] 2023 Nov; Vol. 114, pp. 438-452. Date of Electronic Publication: 2023 Sep 13.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Microglia*
Cognitive Dysfunction*
Rats ; Animals ; Female ; Male ; Sex Characteristics ; Neuroinflammatory Diseases ; Lipopolysaccharides/pharmacology ; Inflammation

Czasopismo naukowe

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Szczegóły

Skocz do pozycji: 14.

Tytuł:: Microglia are involved in regulating histamine-dependent and non-dependent itch transmissions with distinguished signal pathways.
Autorzy:: Yang Y; School of Basic Medical Sciences, Nanchang University, Nanchang, China.; Institute of Life Science, Nanchang University, Nanchang, China.
Mou B; School of Basic Medical Sciences, Nanchang University, Nanchang, China.; Institute of Life Science, Nanchang University, Nanchang, China.
Zhang QR; Institute of Life Science, Nanchang University, Nanchang, China.
Zhao HX; School of Basic Medical Sciences, Nanchang University, Nanchang, China.; Institute of Life Science, Nanchang University, Nanchang, China.
Zhang JY; Institute of Life Science, Nanchang University, Nanchang, China.
Yun X; Institute of Life Science, Nanchang University, Nanchang, China.
Xiong MT; Institute of Life Science, Nanchang University, Nanchang, China.
Liu Y; Institute of Life Science, Nanchang University, Nanchang, China.
Liu YU; Laboratory for Neuroimmunology in Health and Disease, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Pan H; Institute of Life Science, Nanchang University, Nanchang, China.
Ma CL; Institute of Life Science, Nanchang University, Nanchang, China.
Li BM; Institute of Life Science, Nanchang University, Nanchang, China.; Department of Physiology and Institute of Brain Science, School of Basic Medical Sciences, Hangzhou Normal University, Hangzhou, China.
Peng J; School of Basic Medical Sciences, Nanchang University, Nanchang, China.; Institute of Life Science, Nanchang University, Nanchang, China.; Pokaż więcej
Źródło:: Glia [Glia] 2023 Nov; Vol. 71 (11), pp. 2541-2558. Date of Electronic Publication: 2023 Jul 01.
Typ publikacji:: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:: Histamine*/metabolism
Microglia*/metabolism
Mice ; Animals ; Pruritus/chemically induced ; Pruritus/metabolism ; Mice, Transgenic ; Chloroquine/pharmacology ; Signal Transduction ; Pain

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 15.

Tytuł:: Microglial depletion after brain injury prolongs inflammation and impairs brain repair, adult neurogenesis and pro-regenerative signaling.
Autorzy:: Palsamy K; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Chen JY; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Skaggs K; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.; University of Findlay, Findlay, Ohio, USA.
Qadeer Y; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Connors M; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Cutler N; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Richmond J; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Kommidi V; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Poles A; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Affrunti D; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.
Powell C; Michigan Neuroscience Institute, Ann Arbor, Michigan, USA.; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Goldman D; Michigan Neuroscience Institute, Ann Arbor, Michigan, USA.; Department of Biological Chemistry, University of Michigan, Ann Arbor, Michigan, USA.
Parent JM; Department of Neurology, University of Michigan, Ann Arbor, Michigan, USA.; Michigan Neuroscience Institute, Ann Arbor, Michigan, USA.; VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.; Pokaż więcej
Źródło:: Glia [Glia] 2023 Nov; Vol. 71 (11), pp. 2642-2663. Date of Electronic Publication: 2023 Jul 14.
Typ publikacji:: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:: Microglia*
Brain Injuries*
Animals ; Zebrafish ; Brain ; Neurogenesis ; Inflammation ; Catenins ; Mammals

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 16.

Tytuł:: Pannexin-1 opening in neuronal edema causes cell death but also leads to protection via increased microglia contacts.
Autorzy:: Weilinger NL; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: .
Yang K; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Choi HB; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Groten CJ; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Wendt S; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Murugan M; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
Wicki-Stordeur LE; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Bernier LP; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Velayudhan PS; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Zheng J; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
LeDue JM; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Rungta RL; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Department of Stomatology and Department of Neuroscience, Université de Montréal, Montréal, QC, Canada.
Tyson JR; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Snutch TP; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada; Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.
Wu LJ; Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA.
MacVicar BA; Department of Psychiatry, Djavad Mowafaghian Centre for Brain Health, University of British Columbia, Vancouver, BC V6T 1Z3, Canada. Electronic address: .; Pokaż więcej
Źródło:: Cell reports [Cell Rep] 2023 Oct 31; Vol. 42 (10), pp. 113128. Date of Electronic Publication: 2023 Sep 23.
Typ publikacji:: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:: Microglia*/metabolism
Connexins*/metabolism
Reactive Oxygen Species/metabolism ; Cell Death ; Adenosine Triphosphate/metabolism

Czasopismo naukowe

na półce

Szczegóły

Skocz do pozycji: 17.

Tytuł:: Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina.
Autorzy:: Papadogkonaki S; Department of Pharmacology, School of Medicine, University of Crete, Heraklion, 71003 Crete, Greece.
Spyridakos D; Department of Pharmacology, School of Medicine, University of Crete, Heraklion, 71003 Crete, Greece.
Lapokonstantaki E; Department of Chemistry, University of Crete, Heraklion, 71003 Crete, Greece.
Chaniotakis N; Department of Chemistry, University of Crete, Heraklion, 71003 Crete, Greece.
Makriyannis A; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Malamas MS; Center for Drug Discovery and Departments of Chemistry and Chemical Biology and Pharmaceutical Sciences, Northeastern University, Boston, MA 02115, USA.
Thermos K; Department of Pharmacology, School of Medicine, University of Crete, Heraklion, 71003 Crete, Greece.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 28; Vol. 24 (21). Date of Electronic Publication: 2023 Oct 28.
Typ publikacji:: Journal Article
MeSH Terms:: Endocannabinoids*/pharmacology
Endocannabinoids*/metabolism
Microglia*/metabolism
Rats ; Animals ; Receptors, Cannabinoid/metabolism ; Rats, Sprague-Dawley ; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid/metabolism ; Retina/metabolism ; Receptor, Cannabinoid, CB1/metabolism ; Receptor, Cannabinoid, CB2/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 18.

Tytuł:: Distinguishing the effects of systemic CSF1R inhibition by PLX3397 on microglia and peripheral immune cells.
Autorzy:: Okojie AK; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA. .; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA. .
Uweru JO; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Coburn MA; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Li S; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.
Cao-Dao VD; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA.; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA.
Eyo UB; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, VA, USA. .; Center for Brain Immunology and Glia, University of Virginia School of Medicine, Charlottesville, VA, USA. .; Pokaż więcej
Źródło:: Journal of neuroinflammation [J Neuroinflammation] 2023 Oct 21; Vol. 20 (1), pp. 242. Date of Electronic Publication: 2023 Oct 21.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*/metabolism
Lipopolysaccharides*/toxicity
Lipopolysaccharides*/metabolism
Mice ; Animals ; Macrophages ; Aminopyridines/pharmacology ; Receptors, Colony-Stimulating Factor/metabolism ; Receptor Protein-Tyrosine Kinases/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 19.

Tytuł:: Side-Chain Immune Oxysterols Induce Neuroinflammation by Activating Microglia.
Autorzy:: Son Y; Department of Pharmacology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam, Republic of Korea.
Yeo IJ; College of Pharmacy, Kyungpook National University, 80 Daehak-ro, Buk-gu, Daegu 41566, Gyeongbuk, Republic of Korea.; College of Pharmacy and Medical Research Center, Chungbuk National University, Osong-eup, Heungdeok-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Hong JT; College of Pharmacy and Medical Research Center, Chungbuk National University, Osong-eup, Heungdeok-gu, Cheongju 28160, Chungbuk, Republic of Korea.
Eo SK; College of Veterinary Medicine and Bio-Safety Research Institute, Jeonbuk National University, Iksan 54596, Jeonbuk, Republic of Korea.
Lee D; Department of Convergence Medicine, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam, Republic of Korea.
Kim K; Department of Pharmacology, School of Medicine, Pusan National University, Yangsan 50612, Gyeongnam, Republic of Korea.; Pokaż więcej
Źródło:: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 18; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 18.
Typ publikacji:: Journal Article
MeSH Terms:: Microglia*/metabolism
Oxysterols*/metabolism
Animals ; Mice ; Neuroinflammatory Diseases ; Macrophages/metabolism ; Brain/metabolism

Czasopismo naukowe

na półce

Pełny tekst Pełny tekst Szczegóły

Skocz do pozycji: 20.

Tytuł:: Microglia mediated neuroinflammation in neurodegenerative diseases: A review on the cell signaling pathways involved in microglial activation.
Autorzy:: Biswas K; Department of Life Sciences, Presidency University Main campus, 86/1 College Street, Kolkata 700073, India. Electronic address: .; Pokaż więcej
Źródło:: Journal of neuroimmunology [J Neuroimmunol] 2023 Oct 15; Vol. 383, pp. 578180. Date of Electronic Publication: 2023 Aug 26.
Typ publikacji:: Journal Article; Review
MeSH Terms:: Microglia*/metabolism
Neurodegenerative Diseases*/drug therapy
Humans ; Neuroinflammatory Diseases ; Signal Transduction ; Anti-Inflammatory Agents/pharmacology

Czasopismo naukowe

na półce

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Microglia.