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Wyświetlanie 1-13 z 13
Tytuł:
The sodium-glucose co-transporter 2 inhibitor empagliflozin improves diabetes-induced vascular dysfunction in the streptozotocin diabetes rat model by interfering with oxidative stress and glucotoxicity.
Autorzy:
Oelze M; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Kröller-Schön S; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Welschof P; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Jansen T; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Hausding M; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Mikhed Y; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Stamm P; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Mader M; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Zinßius E; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Agdauletova S; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Gottschlich A; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Steven S; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Schulz E; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Bottari SP; Laboratory of Fundamental and Applied, Bioenergetics, INSERM U1055, Grenoble-Alpes Université et Pôle de Biologie, CHU, Grenoble, France.
Mayoux E; Boehringer Ingelheim Pharma GmbH & Co. KG, Ingelheim, Germany.
Münzel T; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Daiber A; 2nd Medical Clinic, Department of Cardiology, Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Pokaż więcej
Źródło:
PloS one [PLoS One] 2014 Nov 17; Vol. 9 (11), pp. e112394. Date of Electronic Publication: 2014 Nov 17 (Print Publication: 2014).
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Diabetes Mellitus, Experimental*
Sodium-Glucose Transporter 2 Inhibitors*
Benzhydryl Compounds/*pharmacology
Diabetes Complications/*metabolism
Diabetic Angiopathies/*metabolism
Glucosides/*pharmacology
Oxidative Stress/*drug effects
Animals ; Benzhydryl Compounds/administration & dosage ; Blood Glucose/drug effects ; Cytokines/genetics ; Cytokines/metabolism ; Diabetes Complications/drug therapy ; Diabetic Angiopathies/drug therapy ; Gene Expression ; Glucose/metabolism ; Glucosides/administration & dosage ; Hemodynamics/drug effects ; Inflammation Mediators/metabolism ; Insulin/blood ; Insulin/metabolism ; Male ; RNA, Messenger/genetics ; Rats ; Receptor for Advanced Glycation End Products ; Receptors, Immunologic/metabolism ; Signal Transduction ; Streptozocin/adverse effects
Czasopismo naukowe
    Wyświetlanie 1-13 z 13

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