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Tytuł :
Experimental bladder regeneration using a poly-L-lactide/silk fibroin scaffold seeded with nanoparticle-labeled allogenic bone marrow stromal cells
Autorzy :
Yudintceva NM
Nashchekina YA
Blinova MI
Orlova NV
Muraviov AN
Vinogradova TI
Sheykhov MG
Shapkova EY
Emeliannikov DV
Yablonskii PK
Samusenko IA
Mikhrina AL
Pakhomov AV
Shevtsov MA
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Temat :
bladder
bone marrow stromal cells
scaffold
superparamagnetic iron oxide nanoparticles
poly-L-lactide polymer
silk fibroin
Medicine (General)
R5-920
Źródło :
International Journal of Nanomedicine, Vol Volume 11, Pp 4521-4533 (2016)
Opis pliku :
electronic resource
Relacje :
https://www.dovepress.com/experimental-bladder-regeneration-using-a-poly-l-lactidesilk-fibroin-s-peer-reviewed-article-IJN; https://doaj.org/toc/1178-2013
Dostęp URL :
https://doaj.org/article/e3a0745981174f85853e707219bbedf3
Czasopismo naukowe
Tytuł :
Neurotherapeutic activity of the recombinant heat shock protein Hsp70 in a model of focal cerebral ischemia in rats
Autorzy :
Shevtsov MA
Nikolaev BP
Yakovleva LY
Dobrodumov AV
Dayneko AS
Shmonin AA
Vlasov TD
Melnikova EV
Vilisov AD
Guzhova IV
Ischenko AM
Mikhrina AL
Galibin OV
Yakovenko IV
Margulis BA
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Temat :
Therapeutics. Pharmacology
RM1-950
Źródło :
Drug Design, Development and Therapy, Vol 2014, Iss default, Pp 639-650 (2014)
Opis pliku :
electronic resource
Relacje :
http://www.dovepress.com/neurotherapeutic-activity-of-the-recombinant-heat-shock-protein-hsp70--peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881
Dostęp URL :
https://doaj.org/article/637b11c7100a40e4a179f17e97998803
Czasopismo naukowe
Tytuł :
Superparamagnetic iron oxide nanoparticles conjugated with epidermal growth factor (SPION–EGF) for targeting brain tumors
Autorzy :
Shevtsov MA
Nikolaev BP
Yakovleva LY
Marchenko YY
Dobrodumov AV
Mikhrina AL
Martynova MG
Bystrova OA
Yakovenko IV
Ischenko AM
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Temat :
Medicine (General)
R5-920
Źródło :
International Journal of Nanomedicine, Vol 2014, Iss Issue 1, Pp 273-287 (2014)
Opis pliku :
electronic resource
Relacje :
http://www.dovepress.com/superparamagnetic-iron-oxide-nanoparticles-conjugated-with-epidermal-g-a15420; https://doaj.org/toc/1178-2013
Dostęp URL :
https://doaj.org/article/396a15a4b8584d33842f4a411a186f78
Czasopismo naukowe
Tytuł :
The Leptin, Dopamine and Serotonin Receptors in Hypothalamic POMC-Neurons of Normal and Obese Rodents.
Autorzy :
Romanova IV; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia. .
Derkach KV; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Mikhrina AL; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Sukhov IB; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Mikhailova EV; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
Shpakov AO; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of Russian Academy of Sciences, Saint Petersburg, Russia.
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Źródło :
Neurochemical research [Neurochem Res] 2018 Apr; Vol. 43 (4), pp. 821-837. Date of Electronic Publication: 2018 Feb 03.
Typ publikacji :
Journal Article
MeSH Terms :
Hypothalamus/*metabolism
Obesity/*metabolism
Pro-Opiomelanocortin/*biosynthesis
Receptors, Dopamine/*biosynthesis
Receptors, Leptin/*biosynthesis
Receptors, Serotonin/*biosynthesis
Animals ; Female ; Hypothalamus/chemistry ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/chemistry ; Neurons/metabolism ; Pro-Opiomelanocortin/analysis ; Rats ; Rats, Wistar ; Receptors, Dopamine/analysis ; Receptors, Leptin/analysis ; Receptors, Serotonin/analysis ; Rodentia
Czasopismo naukowe
Tytuł :
Metabolic parameters and functional state of hypothalamic signaling systems in A /a mice with genetic predisposition to obesity and the effect of metformin.
Autorzy :
Derkach KV; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Zakharova IO; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Romanova IV; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Zorina II; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Mikhrina AL; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia.
Shpakov AO; Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, 194223, Russia. .
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Źródło :
Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2017 Nov; Vol. 477 (1), pp. 377-381. Date of Electronic Publication: 2018 Jan 03.
Typ publikacji :
Journal Article
MeSH Terms :
Genetic Predisposition to Disease*
Hypothalamus*/drug effects
Metformin/*pharmacology
Metformin/*therapeutic use
Obesity/*drug therapy
Obesity/*genetics
Animals ; Mice ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Signal Transduction/drug effects
Czasopismo naukowe
Tytuł :
Localization of the dopamine receptors of types 1 and 2 on the bodies of POMC-expressing neurons of the arcuate nucleus of the hypothalamus in mice and rats.
Autorzy :
Romanova IV; Sechenov Institute of Evolutionary Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia. .
Mikhrina AL; Sechenov Institute of Evolutionary Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
Shpakov AO; Sechenov Institute of Evolutionary Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
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Źródło :
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections [Dokl Biol Sci] 2017 Jan; Vol. 472 (1), pp. 11-14. Date of Electronic Publication: 2017 Apr 21.
Typ publikacji :
Journal Article
MeSH Terms :
Arcuate Nucleus of Hypothalamus*/cytology
Arcuate Nucleus of Hypothalamus*/metabolism
Neurons*/cytology
Neurons*/metabolism
Gene Expression Regulation/*physiology
Pro-Opiomelanocortin/*biosynthesis
Receptors, Dopamine D1/*metabolism
Receptors, Dopamine D2/*metabolism
Animals ; Male ; Mice ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Detection of experimental myocardium infarction in rats by MRI using heat shock protein 70 conjugated superparamagnetic iron oxide nanoparticle.
Autorzy :
Shevtsov MA; Institute of Cytology of the Russian Academy of Sciences (RAS), St. Petersburg, Russia; A.L. Polenov Russian Research Scientific Institute of Neurosurgery, St. Petersburg, Russia; Technische Universität München, Klinikum rechts der Isar, Radiation Oncology, Munich, Germany. Electronic address: .
Nikolaev BP; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Ryzhov VA; National Research Centre 'Kurchatov Institute' B.P. Konstantinov Petersburg Nuclear Physics Institute, Gatchina, Russia.
Yakovleva LY; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Dobrodumov AV; Institute of Macromolecular Compounds of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Marchenko YY; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Margulis BA; Institute of Cytology of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Pitkin E; The Wharton School, University of Pennsylvania, Philadelphia, PA, USA.
Mikhrina AL; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Guzhova IV; Institute of Cytology of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Multhoff G; Technische Universität München, Klinikum rechts der Isar, Radiation Oncology, Munich, Germany.
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Źródło :
Nanomedicine : nanotechnology, biology, and medicine [Nanomedicine] 2016 Apr; Vol. 12 (3), pp. 611-621. Date of Electronic Publication: 2015 Dec 02.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Contrast Media/*chemistry
Ferric Compounds/*chemistry
HSP70 Heat-Shock Proteins/*chemistry
Magnetic Resonance Imaging/*methods
Magnetite Nanoparticles/*chemistry
Myocardial Infarction/*diagnostic imaging
Animals ; Contrast Media/pharmacokinetics ; Ferric Compounds/pharmacokinetics ; HSP70 Heat-Shock Proteins/pharmacokinetics ; Magnetite Nanoparticles/analysis ; Male ; Myocardium/pathology ; Rats, Wistar ; Tissue Distribution
Czasopismo naukowe
Tytuł :
Ionizing radiation improves glioma-specific targeting of superparamagnetic iron oxide nanoparticles conjugated with cmHsp70.1 monoclonal antibodies (SPION-cmHsp70.1).
Autorzy :
Shevtsov MA; Institute of Cytology of the Russian Academy of Sciences (RAS), Tikhoretsky ave., 4, St. Petersburg, 194064, Russia. .
Nikolaev BP
Ryzhov VA
Yakovleva LY
Marchenko YY
Parr MA
Rolich VI
Mikhrina AL
Dobrodumov AV
Pitkin E
Multhoff G
Pokaż więcej
Źródło :
Nanoscale [Nanoscale] 2015 Dec 28; Vol. 7 (48), pp. 20652-64. Date of Electronic Publication: 2015 Nov 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Antibodies, Monoclonal, Murine-Derived*/chemistry
Antibodies, Monoclonal, Murine-Derived*/pharmacology
Brain Neoplasms/*therapy
Chemoradiotherapy/*methods
Drug Delivery Systems/*methods
Gamma Rays/*therapeutic use
Glioma/*therapy
HSP70 Heat-Shock Proteins/*antagonists & inhibitors
Magnetite Nanoparticles/*chemistry
Animals ; HSP70 Heat-Shock Proteins/chemistry ; HeLa Cells ; Humans ; K562 Cells ; Male ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Recombinant interleukin-1 receptor antagonist conjugated to superparamagnetic iron oxide nanoparticles for theranostic targeting of experimental glioblastoma.
Autorzy :
Shevtsov MA; Institute of Cytology of the Russian Academy of Sciences (RAS), St. Petersburg, Russia; A.L. Polenov Russian Research Scientific Institute of Neurosurgery, St. Petersburg, Russia. Electronic address: .
Nikolaev BP; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Yakovleva LY; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Dobrodumov AV; Institute of Macromolecular Compounds of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Zhakhov AV; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Mikhrina AL; I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Pitkin E; Wharton School, University of Pennsylvania, Philadelphia, PA, USA.
Parr MA; V.F. Fock Institute of Physics, St. Petersburg State University, St. Petersburg, Russia.
Rolich VI; V.F. Fock Institute of Physics, St. Petersburg State University, St. Petersburg, Russia.
Simbircev AS; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
Ischenko AM; Research Institute of Highly Pure Biopreparations, St. Petersburg, Russia.
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Źródło :
Neoplasia (New York, N.Y.) [Neoplasia] 2015 Jan; Vol. 17 (1), pp. 32-42.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Ferric Compounds*/chemistry
Magnetite Nanoparticles*/chemistry
Brain Neoplasms/*diagnosis
Glioblastoma/*diagnosis
Receptors, Interleukin-1/*antagonists & inhibitors
Recombinant Proteins/*administration & dosage
Animals ; Blood-Brain Barrier/metabolism ; Brain/pathology ; Brain Edema/drug therapy ; Brain Edema/metabolism ; Brain Edema/pathology ; Brain Neoplasms/drug therapy ; Brain Neoplasms/mortality ; Cell Line, Tumor ; Contrast Media ; Glioblastoma/drug therapy ; Glioblastoma/mortality ; Magnetic Resonance Imaging ; Male ; Neoplasms, Experimental ; Rats ; Recombinant Proteins/chemistry ; Recombinant Proteins/pharmacokinetics
Czasopismo naukowe
Tytuł :
Effective immunotherapy of rat glioblastoma with prolonged intratumoral delivery of exogenous heat shock protein Hsp70.
Autorzy :
Shevtsov MA; Laboratory of Cell Protection Mechanisms, Institute of Cytology of the Russian Academy of Sciences (RAS), St. Petersburg, Russia.
Pozdnyakov AV
Mikhrina AL
Yakovleva LY
Nikolaev BP
Dobrodumov AV
Komarova EY
Meshalkina DA
Ischenko AM
Pitkin E
Guzhova IV
Margulis BA
Pokaż więcej
Źródło :
International journal of cancer [Int J Cancer] 2014 Nov 01; Vol. 135 (9), pp. 2118-28. Date of Electronic Publication: 2014 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Immunotherapy*
Brain Neoplasms/*therapy
CD8-Positive T-Lymphocytes/*immunology
Cancer Vaccines/*administration & dosage
Glioblastoma/*therapy
HSP70 Heat-Shock Proteins/*metabolism
Animals ; Apoptosis ; Brain Neoplasms/immunology ; Brain Neoplasms/metabolism ; Cell Proliferation ; Drug Delivery Systems ; Flow Cytometry ; Glioblastoma/immunology ; Glioblastoma/metabolism ; HSP70 Heat-Shock Proteins/administration & dosage ; Humans ; Immunoenzyme Techniques ; Injections, Intralesional ; Interferon-gamma/metabolism ; Lymphocytes, Tumor-Infiltrating/immunology ; Male ; Rats ; T-Lymphocytes, Cytotoxic/immunology ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Analysis of development of morphofunctional interconnections between CART- and AGRP-ergic neurons with dopaminergic structures in ontogenesis of mammals].
Autorzy :
Romanova IV
Mikhrina AL
Chernysheva MP
Pokaż więcej
Źródło :
Zhurnal evoliutsionnoi biokhimii i fiziologii [Zh Evol Biokhim Fiziol] 2014 Sep-Oct; Vol. 50 (5), pp. 392-8.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Neurogenesis*
Agouti-Related Protein/*metabolism
Dopaminergic Neurons/*physiology
Hypothalamus/*physiology
Mesencephalon/*physiology
Nerve Tissue Proteins/*metabolism
Agouti-Related Protein/genetics ; Animals ; Dopaminergic Neurons/cytology ; Dopaminergic Neurons/metabolism ; Hypothalamus/cytology ; Hypothalamus/embryology ; Mesencephalon/cytology ; Mesencephalon/embryology ; Nerve Tissue Proteins/genetics ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
Tumor targeting using magnetic nanoparticle Hsp70 conjugate in a model of C6 glioma.
Autorzy :
Shevtsov MA; Corresponding author: Maxim A. Shevtsov, MD, PhD, Laboratory of Cell Protection Mechanisms, Institute of Cytology of Russian Academy of Sciences, Tikhoretsky Ave. 4, 194064, St. Petersburg, Russia. .
Yakovleva LY
Nikolaev BP
Marchenko YY
Dobrodumov AV
Onokhin KV
Onokhina YS
Selkov SA
Mikhrina AL
Guzhova IV
Martynova MG
Bystrova OA
Ischenko AM
Margulis BA
Pokaż więcej
Źródło :
Neuro-oncology [Neuro Oncol] 2014 Jan; Vol. 16 (1), pp. 38-49. Date of Electronic Publication: 2013 Dec 04.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Disease Models, Animal*
Brain Neoplasms/*metabolism
Glioma/*metabolism
HSP70 Heat-Shock Proteins/*metabolism
Magnetite Nanoparticles/*administration & dosage
Animals ; Brain Neoplasms/pathology ; Glioma/pathology ; Humans ; Injections, Intravenous ; Magnetic Resonance Imaging ; Magnetite Nanoparticles/chemistry ; Male ; Microscopy, Confocal ; Microscopy, Electron ; Rats ; Rats, Wistar ; Recombinant Proteins/genetics ; Recombinant Proteins/metabolism ; Tumor Cells, Cultured
Czasopismo naukowe
Tytuł :
[Participation of Agouti related peptide in machanisms of wakefulness-sleep cycle regulation].
Autorzy :
Romanova IV
Mikhrina AL
Pokaż więcej
Źródło :
Fiziologiia cheloveka [Fiziol Cheloveka] 2013 Nov-Dec; Vol. 39 (6), pp. 24-30.
Typ publikacji :
English Abstract; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Agouti-Related Protein/*metabolism
Dopaminergic Neurons/*metabolism
Hypothalamus/*metabolism
Nerve Tissue Proteins/*metabolism
Nucleus Accumbens/*metabolism
Sleep/*physiology
Animals ; Dopamine/metabolism ; Dopaminergic Neurons/cytology ; Humans ; Hypothalamus/cytology ; Male ; Nucleus Accumbens/cytology ; Rats ; Rats, Wistar
Czasopismo naukowe
Tytuł :
[A role of AGRP on dopamine brain neurons regulation].
Autorzy :
Mikhrina AL
Romanova IV
Pokaż więcej
Źródło :
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2013 Sep; Vol. 99 (9), pp. 1036-44.
Typ publikacji :
English Abstract; Journal Article
MeSH Terms :
Agouti-Related Protein/*administration & dosage
Dopaminergic Neurons/*ultrastructure
Hypothalamus/*metabolism
Tyrosine 3-Monooxygenase/*biosynthesis
Animals ; Axons/metabolism ; Axons/ultrastructure ; Dopamine/metabolism ; Hypothalamus/ultrastructure ; Mesencephalon/metabolism ; Mesencephalon/ultrastructure ; Mice ; Rats
Czasopismo naukowe
Tytuł :
[Raction of dopaminergic and vasopressinergic systems in sleep deprivation in rats].
Autorzy :
Oganesian GA
Romanova IV
Mikhrina AL
Paskarenko NM
Kuzik VV
Pokaż więcej
Źródło :
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2012 Nov; Vol. 98 (11), pp. 1307-13.
Typ publikacji :
English Abstract; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Benzazepines/*pharmacology
Dopamine Antagonists/*pharmacology
Receptors, AMPA/*metabolism
Sleep Deprivation/*metabolism
Vasopressins/*metabolism
Animals ; Male ; Paraventricular Hypothalamic Nucleus/metabolism ; Paraventricular Hypothalamic Nucleus/physiopathology ; Rats ; Rats, Wistar ; Receptors, Dopamine D1/metabolism ; Receptors, Dopamine D2/metabolism ; Sleep Deprivation/physiopathology ; Supraoptic Nucleus/metabolism ; Supraoptic Nucleus/physiopathology
Czasopismo naukowe
Tytuł :
[Effect of retinol on interaction of the protein period1, oxytocin, and GABA at the prenatal period of formation of the circadian clock-mechanism in rats].
Autorzy :
Chernysheva MP
Romanova IV
Mikhrina AL
Pokaż więcej
Źródło :
Zhurnal evoliutsionnoi biokhimii i fiziologii [Zh Evol Biokhim Fiziol] 2012 Sep-Oct; Vol. 48 (5), pp. 481-6.
Typ publikacji :
English Abstract; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Circadian Rhythm/*drug effects
Embryo, Mammalian/*metabolism
Nerve Tissue Proteins/*biosynthesis
Oxytocin/*metabolism
Period Circadian Proteins/*biosynthesis
Vitamin A/*pharmacology
Vitamins/*pharmacology
gamma-Aminobutyric Acid/*metabolism
Animals ; Female ; Gene Expression Regulation/drug effects ; Gene Expression Regulation/physiology ; Hypothalamus, Anterior/embryology ; Nuclear Receptor Subfamily 1, Group F, Member 1/metabolism ; Pregnancy ; Rats ; Time Factors
Czasopismo naukowe
Tytuł :
[Immunohistochemical study of CART-peptide in striato-nigral projections at dopamine loss].
Autorzy :
Romanova IV
Chesnokova AIu
Mikhrina AL
Pokaż więcej
Źródło :
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova [Ross Fiziol Zh Im I M Sechenova] 2012 Aug; Vol. 98 (8), pp. 980-9.
Typ publikacji :
English Abstract; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Dopamine*
Corpus Striatum/*metabolism
Dopaminergic Neurons/*metabolism
Nerve Tissue Proteins/*metabolism
Peptide Fragments/*metabolism
Substantia Nigra/*metabolism
Acetylcysteine/analogs & derivatives ; Acetylcysteine/pharmacology ; Animals ; Corpus Striatum/cytology ; Cysteine Proteinase Inhibitors/pharmacology ; Dopaminergic Neurons/cytology ; Immunohistochemistry ; Male ; Nucleus Accumbens/cytology ; Nucleus Accumbens/metabolism ; Rats ; Rats, Wistar ; Substantia Nigra/cytology ; alpha-Methyltyrosine/pharmacology
Czasopismo naukowe

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