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Wyświetlanie 1-4 z 4
Tytuł:
A glucagon analogue decreases body weight in mice via signalling in the liver.
Autorzy:
Hinds CE; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Owen BM; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Hope DCD; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Pickford P; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Jones B; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Tan TM; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Minnion JS; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK.
Bloom SR; Section of Investigative Medicine, Department of Metabolism, Digestion, and Reproduction, Imperial College London, London, W12 0NN, UK. .
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Źródło:
Scientific reports [Sci Rep] 2021 Nov 19; Vol. 11 (1), pp. 22577. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Obesity Agents/*pharmacology
Glucagon/*pharmacology
Hepatocytes/*drug effects
Liver/*drug effects
Receptors, Glucagon/*agonists
Weight Loss/*drug effects
Animals ; Anti-Obesity Agents/pharmacokinetics ; Biological Variation, Population ; Dose-Response Relationship, Drug ; Female ; Glucagon/analogs & derivatives ; Glucagon/pharmacokinetics ; HEK293 Cells ; Hepatocytes/metabolism ; Humans ; Liver/metabolism ; Male ; Mice, Inbred C57BL ; Mice, Knockout ; Rats, Wistar ; Receptors, Glucagon/genetics ; Receptors, Glucagon/metabolism ; Signal Transduction ; Mice ; Rats
Czasopismo naukowe
Tytuł:
Glucagon and GLP-1 inhibit food intake and increase c-fos expression in similar appetite regulating centres in the brainstem and amygdala.
Autorzy:
Parker JA; Hammersmith Hospital, Section of Investigative Medicine, Imperial College London, London, UK.
McCullough KA
Field BC
Minnion JS
Martin NM
Ghatei MA
Bloom SR
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2013 Oct; Vol. 37 (10), pp. 1391-8. Date of Electronic Publication: 2013 Jan 22.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amygdala/*metabolism
Appetite/*physiology
Brain Stem/*metabolism
Glucagon/*metabolism
Glucagon-Like Peptide 1/*metabolism
Proto-Oncogene Proteins c-fos/*metabolism
Animals ; Appetite/drug effects ; Dose-Response Relationship, Drug ; Eating/drug effects ; Energy Metabolism ; Glucagon/pharmacology ; Glucagon-Like Peptide 1/pharmacology ; Injections, Intraperitoneal ; Male ; Mice ; Proto-Oncogene Proteins c-fos/drug effects
Czasopismo naukowe
Tytuł:
Peptide YY 3-36 and pancreatic polypeptide differentially regulate hypothalamic neuronal activity in mice in vivo as measured by manganese-enhanced magnetic resonance imaging.
Autorzy:
Hankir MK; Division of Diabetes, Endocrinology and Metabolism, Imperial College London, London, UK.
Parkinson JR
Minnion JS
Addison ML
Bloom SR
Bell JD
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Źródło:
Journal of neuroendocrinology [J Neuroendocrinol] 2011 Apr; Vol. 23 (4), pp. 371-80.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Hypothalamus/*cytology
Magnetic Resonance Imaging/*methods
Manganese/*metabolism
Neurons/*metabolism
Pancreatic Polypeptide/*metabolism
Peptide YY/*metabolism
Animals ; Brain Stem/drug effects ; Brain Stem/metabolism ; Eating/drug effects ; Fasting ; Humans ; Hypothalamus/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Neurons/cytology ; Neurons/drug effects ; Pancreatic Polypeptide/pharmacology ; Peptide Fragments ; Peptide YY/pharmacology
Czasopismo naukowe
Tytuł:
Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents.
Autorzy:
Liu YL; Department of Investigative Medicine, Imperial College Faculty of Medicine, Hammersmith Hospital, London, UK.
Ford HE
Druce MR
Minnion JS
Field BC
Shillito JC
Baxter J
Murphy KG
Ghatei MA
Bloom SR
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Źródło:
International journal of obesity (2005) [Int J Obes (Lond)] 2010 Dec; Vol. 34 (12), pp. 1715-25. Date of Electronic Publication: 2010 Jun 08.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Anti-Obesity Agents/*pharmacology
Body Weight/*drug effects
Gastrointestinal Hormones/*pharmacology
Glucagon-Like Peptide 1/*pharmacology
Peptide Hormones/*pharmacology
Receptors, Glucagon/*drug effects
Animals ; Body Weight/physiology ; Eating/drug effects ; Energy Metabolism/drug effects ; Glucagon-Like Peptide-1 Receptor ; Injections, Subcutaneous ; Male ; Mice ; Mice, Inbred C57BL ; Rats ; Rats, Wistar ; Weight Loss/drug effects ; Weight Loss/physiology
Czasopismo naukowe
    Wyświetlanie 1-4 z 4

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