Autor: "Mintas, Mladen" - OpacWWW

Skocz do pozycji: 1 1.

Tytuł :: Novel halogenated 3-deazapurine, 7-deazapurine and alkylated 9-deazapurine derivatives of L-ascorbic or imino-L-ascorbic acid: Synthesis, antitumour and antiviral activity evaluations.
Autorzy :: Stipković Babić M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Makuc D; Slovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia; EN-FIST Centre of Excellence, Trg Osvobodilne fronte 13, SI-1000 Ljubljana, Slovenia.
Plavec J; Slovenian NMR Centre, National Institute of Chemistry, Hajdrihova 19, SI-1000 Ljubljana, Slovenia; EN-FIST Centre of Excellence, Trg Osvobodilne fronte 13, SI-1000 Ljubljana, Slovenia.
Martinović T; Department of Biotechnology, University of Rijeka, Radmile Matejčić 2, HR-51000 Rijeka, Croatia.
Kraljević Pavelić S; Department of Biotechnology, University of Rijeka, Radmile Matejčić 2, HR-51000 Rijeka, Croatia.
Pavelić K; Department of Biotechnology, University of Rijeka, Radmile Matejčić 2, HR-51000 Rijeka, Croatia.
Snoeck R; Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
Andrei G; Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
Schols D; Department of Microbiology and Immunology, Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium.
Wittine K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Mintas M; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia. Electronic address: mladen.mintas@fkit.hr.; Pokaż więcej
Źródło :: European journal of medicinal chemistry [Eur J Med Chem] 2015 Sep 18; Vol. 102, pp. 288-302. Date of Electronic Publication: 2015 Aug 10.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*pharmacology
Antiviral Agents/*pharmacology
Ascorbic Acid/*chemistry
Ascorbic Acid/*pharmacology
Cytomegalovirus/*drug effects
Purines/*chemistry
Purines/*pharmacology
Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Ascorbic Acid/chemical synthesis ; Cell Line ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; Humans ; Mice ; Microbial Sensitivity Tests ; Molecular Structure ; Purines/chemical synthesis ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 2 2.

Tytuł :: Antitumor mechanisms of amino Acid hydroxyurea derivatives in the metastatic colon cancer model.
Autorzy :: Saban N; Rudjer Bošković Institute, Division of Molecular Medicine, Bijenička 54, Zagreb 10000, Croatia. .
Stepanić V
Vučinić S
Horvatić A
Cindrić M
Perković I
Zorc B
Oršolić N
Mintas M
Pavelić K
Pavelić SK; Pokaż więcej
Źródło :: International journal of molecular sciences [Int J Mol Sci] 2013 Dec 04; Vol. 14 (12), pp. 23654-71. Date of Electronic Publication: 2013 Dec 04.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Amino Acids/*chemistry
Antineoplastic Agents/*chemistry
Hydroxyurea/*analogs & derivatives
Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Binding Sites ; Cell Cycle Checkpoints/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Colonic Neoplasms/metabolism ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Electrophoresis, Gel, Two-Dimensional ; Histone Deacetylases/chemistry ; Histone Deacetylases/metabolism ; Humans ; Hydroxyurea/pharmacology ; Hydroxyurea/therapeutic use ; Male ; Mice ; Mice, Inbred BALB C ; Molecular Docking Simulation ; Protein Structure, Tertiary ; Proteome/analysis ; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 3 3.

Tytuł :: The novel [4,5-e][1,3]diazepine-4,8-dione and acyclic carbamoyl imino-ureido derivatives of imidazole: synthesis, anti-viral and anti-tumor Activity evaluations.
Autorzy :: Wittine K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, Zagreb HR-10000, Croatia. .
Poljak K
Kovač M
Makuc D
Plavec J
Balzarini J
Martinović T
Pavelić SK
Pavelić K
Mintas M; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2013 Oct 30; Vol. 18 (11), pp. 13385-97. Date of Electronic Publication: 2013 Oct 30.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemistry
Antineoplastic Agents/*pharmacology
Antiviral Agents/*chemistry
Antiviral Agents/*pharmacology
Imidazoles/*chemistry
Imidazoles/*pharmacology
Antineoplastic Agents/adverse effects ; Antiviral Agents/adverse effects ; Cell Line ; Cell Line, Tumor ; Cell Proliferation/drug effects ; DNA Viruses/drug effects ; HeLa Cells ; Humans ; Imidazoles/adverse effects ; RNA Viruses/drug effects ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 4 4.

Tytuł :: Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity.
Autorzy :: Benci K; Department of Organic Chemistry, University of Zagreb, Zagreb, Croatia.
Mandić L
Suhina T
Sedić M
Klobučar M
Kraljević Pavelić S
Pavelić K
Wittine K
Mintas M; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2012 Sep 12; Vol. 17 (9), pp. 11010-25. Date of Electronic Publication: 2012 Sep 12.
Typ publikacji :: Journal Article
MeSH Terms :: Antineoplastic Agents/*pharmacology
Coumarins/*chemistry
Coumarins/*pharmacology
Imidazoles/*chemistry
Purines/*chemistry
Triazoles/*chemistry
Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; HeLa Cells ; Hep G2 Cells ; Humans ; MCF-7 Cells ; Molecular Structure ; Neoplasms/drug therapy ; Nucleosides/chemistry ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 5 5.

Tytuł :: Novel 1,2,4-triazole and imidazole derivatives of L-ascorbic and imino-ascorbic acid: synthesis, anti-HCV and antitumor activity evaluations.
Autorzy :: Wittine K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, HR-10000 Zagreb, Croatia.
Stipković Babić M
Makuc D
Plavec J
Kraljević Pavelić S
Sedić M
Pavelić K
Leyssen P
Neyts J
Balzarini J
Mintas M; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2012 Jun 01; Vol. 20 (11), pp. 3675-85. Date of Electronic Publication: 2012 Feb 15.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Antiviral Agents/*chemical synthesis
Antiviral Agents/*pharmacology
Ascorbic Acid/*analogs & derivatives
Hepacivirus/*drug effects
Imidazoles/*chemistry
Triazoles/*chemistry
Animals ; Antineoplastic Agents/chemistry ; Antiviral Agents/chemistry ; Ascorbic Acid/chemistry ; Cell Line, Tumor ; Dogs ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; Hepacivirus/physiology ; Humans ; IMP Dehydrogenase/antagonists & inhibitors ; Imidazoles/pharmacology ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Virus Replication/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 6 6.

Tytuł :: Benzylidene-bis-(4-hydroxycoumarin) and benzopyrano-coumarin derivatives: synthesis, ¹H/¹³C-NMR conformational and X-ray crystal structure studies and in vitro antiviral activity evaluations.
Autorzy :: Završnik D; Faculty of Pharmacy, University of Sarajevo, Čekaluša 90, Sarajevo BA-71000, Bosnia and Hercegovina.
Muratović S
Makuc D
Plavec J
Cetina M
Nagl A
Clercq ED
Balzarini J
Mintas M; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2011 Jul 19; Vol. 16 (7), pp. 6023-40. Date of Electronic Publication: 2011 Jul 19.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: 4-Hydroxycoumarins/*chemistry
Antiviral Agents/*chemistry
Antiviral Agents/*pharmacology
Coumarins/*chemistry
Magnetic Resonance Spectroscopy/*methods
X-Ray Diffraction/*methods
Animals ; Cats ; Cell Line ; Cell Line, Tumor ; Dogs ; Herpesvirus 1, Human/drug effects ; Herpesvirus 2, Human/drug effects ; Molecular Structure
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 7 7.

Tytuł :: Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations.
Autorzy :: Benci K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia.
Suhina T
Mandić L
Pavelić SK
Paravić AT
Pavelić K
Balzarini J
Wittine K
Mintas M; Pokaż więcej
Źródło :: Antiviral chemistry & chemotherapy [Antivir Chem Chemother] 2011 Jul 04; Vol. 21 (6), pp. 221-30. Date of Electronic Publication: 2011 Jul 04.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antiviral Agents/*chemical synthesis
Antiviral Agents/*pharmacology
Cytostatic Agents/*chemical synthesis
Cytostatic Agents/*pharmacology
Purine Nucleosides/*chemistry
Animals ; Antiviral Agents/chemistry ; Cell Line, Tumor ; Cells, Cultured ; Cytostatic Agents/chemistry ; DNA Viruses/drug effects ; Dogs ; Drug Evaluation, Preclinical ; Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Fibroblasts/cytology ; Fibroblasts/drug effects ; Herpesvirus 1, Human/enzymology ; Herpesvirus 3, Human/enzymology ; Humans ; Magnetic Resonance Spectroscopy ; Molecular Structure ; Phosphorylation ; Purine Nucleosides/pharmacology ; RNA Viruses/drug effects ; Structure-Activity Relationship ; Thymidine/metabolism ; Thymidine Kinase/antagonists & inhibitors ; Triazoles/chemistry
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 8 8.

Tytuł :: Evaluation of in vitro biological activity of O-alkylated hydroxamic derivatives of some nonsteroidal anti-inflammatory drugs.
Autorzy :: Pavelić SK; Department of Biotechnology, University of Rijeka, Rijeka, Croatia.
Sedić M
Poznić M
Rajić Z
Zorc B
Pavelić K
Balzarini J
Mintas M; Pokaż więcej
Źródło :: Anticancer research [Anticancer Res] 2010 Oct; Vol. 30 (10), pp. 3987-94.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Hydroxamic Acids/*pharmacology
Animals ; Antineoplastic Agents/pharmacology ; Antiviral Agents/pharmacology ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Screening Assays, Antitumor ; HeLa Cells ; Humans ; Leukemia L1210/drug therapy ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 9 9.

Tytuł :: The unsaturated acyclic nucleoside analogues bearing a sterically constrained (Z)-4'-benzamido-2'-butenyl moiety: Synthesis, X-ray crystal structure study, cytostatic and antiviral activity evaluations.
Autorzy :: Benci K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Wittine K
Radan M
Cetina M
Sedić M
Kraljević Pavelić S
Pavelić K
Clercq ED
Mintas M; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2010 Sep 01; Vol. 18 (17), pp. 6249-57. Date of Electronic Publication: 2010 Aug 07.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Adenine/*analogs & derivatives
Antineoplastic Agents/*chemistry
Antiviral Agents/*chemistry
Nucleosides/*chemistry
Nucleosides/*pharmacology
Pyrimidines/*chemistry
Adenine/chemistry ; Adenine/pharmacology ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Antiviral Agents/chemical synthesis ; Antiviral Agents/pharmacology ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Epoxy Compounds ; Humans ; Isomerism ; Molecular Structure ; Nucleosides/chemical synthesis ; Pyrimidines/chemical synthesis ; Pyrimidines/pharmacology ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 10 10.

Tytuł :: Cytostatic and antiviral activity evaluations of hydroxamic derivatives of some non-steroidal anti-inflammatory drugs.
Autorzy :: Rajic Z; Faculty of Pharmacy and Biochemistry, University of Zagreb, HR-10000 Zagreb, Croatia.
Butula I
Zorc B
Kraljevic Pavelic S
Hock K
Pavelic K
Naesens L
De Clercq E
Balzarini J
Przyborowska M
Ossowski T
Mintas M; Pokaż więcej
Źródło :: Chemical biology & drug design [Chem Biol Drug Des] 2009 Mar; Vol. 73 (3), pp. 328-38.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Anti-Inflammatory Agents, Non-Steroidal/*pharmacology
Antiviral Agents/*pharmacology
Cytostatic Agents/*pharmacology
Hydroxamic Acids/*pharmacology
Anti-Inflammatory Agents, Non-Steroidal/chemical synthesis ; Anti-Inflammatory Agents, Non-Steroidal/chemistry ; Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Cell Line, Tumor ; Cytostatic Agents/chemical synthesis ; Cytostatic Agents/chemistry ; Drug Screening Assays, Antitumor ; HeLa Cells ; Humans ; Hydroxamic Acids/chemical synthesis ; Hydroxamic Acids/chemistry ; Influenza A virus/drug effects
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 11 11.

Tytuł :: Novel lipophilic hydroxyurea derivatives: synthesis, cytostatic and antiviral activity evaluations.
Autorzy :: Perković I; Department of Medicinal Chemistry, Faculty of Pharmacy and Biochemistry, A. Kovacića 1, HR-10 000 Zagreb, Croatia.
Butula I
Zorc B
Hock K
Kraljević Pavelić S
Pavelić K
Clercq ED
Balzarini J
Mintas M; Pokaż więcej
Źródło :: Chemical biology & drug design [Chem Biol Drug Des] 2008 Jun; Vol. 71 (6), pp. 546-53. Date of Electronic Publication: 2008 Apr 10.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemistry
Antiviral Agents/*chemistry
Hydroxyurea/*analogs & derivatives
Cell Line, Tumor ; Cell Proliferation/drug effects ; Humans ; Hydrophobic and Hydrophilic Interactions ; Hydroxyurea/chemical synthesis ; Hydroxyurea/pharmacology ; Inhibitory Concentration 50 ; Structure-Activity Relationship ; Viruses/drug effects
: Czasopismo naukowe

Szczegóły Pełny tekst

Skocz do pozycji: 12 12.

Tytuł :: Synthesis, cytostatic and anti-HIV evaluations of the new unsaturated acyclic C-5 pyrimidine nucleoside analogues.
Autorzy :: Gazivoda T; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Raić-Malić S
Kristafor V
Makuc D
Plavec J
Bratulić S
Kraljević-Pavelić S
Pavelić K
Naesens L
Andrei G
Snoeck R
Balzarini J
Mintas M; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2008 May 15; Vol. 16 (10), pp. 5624-34. Date of Electronic Publication: 2008 Apr 01.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Anti-HIV Agents/*chemical synthesis
Anti-HIV Agents/*pharmacology
Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Leukemia L1210/*drug therapy
Pyrimidine Nucleosides/*chemical synthesis
Pyrimidine Nucleosides/*pharmacology
Animals ; Anti-HIV Agents/chemistry ; Antineoplastic Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Design ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; HIV-1/drug effects ; HIV-2/drug effects ; HeLa Cells ; Humans ; Leukemia L1210/pathology ; Mice ; Microbial Sensitivity Tests ; Molecular Structure ; Pyrimidine Nucleosides/chemistry ; Stereoisomerism ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 13 13.

Tytuł :: The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations.
Autorzy :: Wittine K; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Benci K
Pavelić SK
Pavelić K
Mintas M; Pokaż więcej
Źródło :: Nucleic acids symposium series (2004) [Nucleic Acids Symp Ser (Oxf)] 2008 (52), pp. 601-2.
Typ publikacji :: Journal Article
MeSH Terms :: Antiviral Agents/*chemical synthesis
Cytostatic Agents/*chemical synthesis
Purine Nucleosides/*chemical synthesis
Pyrimidine Nucleosides/*chemical synthesis
Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Cytostatic Agents/chemistry ; Cytostatic Agents/pharmacology ; Purine Nucleosides/chemistry ; Purine Nucleosides/pharmacology ; Pyrimidine Nucleosides/chemistry ; Pyrimidine Nucleosides/pharmacology
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 14 14.

Tytuł :: Synthesis and antiviral and cytostatic evaluations of the new C-5 substituted pyrimidine and furo[2,3-d]pyrimidine 4',5'-didehydro-L-ascorbic acid derivatives.
Autorzy :: Gazivoda T; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Sokcević M
Kralj M
Suman L
Pavelić K
De Clercq E
Andrei G
Snoeck R
Balzarini J
Mintas M
Raić-Malić S; Pokaż więcej
Źródło :: Journal of medicinal chemistry [J Med Chem] 2007 Aug 23; Vol. 50 (17), pp. 4105-12. Date of Electronic Publication: 2007 Aug 02.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemical synthesis
Antiviral Agents/*chemical synthesis
Ascorbic Acid/*analogs & derivatives
Ascorbic Acid/*chemical synthesis
Pyrimidines/*chemical synthesis
Pyrimidinones/*chemical synthesis
Animals ; Antineoplastic Agents/pharmacology ; Antiviral Agents/pharmacology ; Ascorbic Acid/pharmacology ; Cell Line ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Humans ; Mice ; Pyrimidines/pharmacology ; Pyrimidinones/pharmacology ; Stereoisomerism ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 15 15.

Tytuł :: Novel C-6 fluorinated acyclic side chain pyrimidine derivatives: synthesis, (1)H and (13)C NMR conformational studies, and antiviral and cytostatic evaluations.
Autorzy :: Prekupec S; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 20, P.O. Box 177, HR-10000 Zagreb, Croatia.
Makuc D
Plavec J
Suman L
Kralj M
Pavelić K
Balzarini J
Clercq ED
Mintas M
Raić-Malić S; Pokaż więcej
Źródło :: Journal of medicinal chemistry [J Med Chem] 2007 Jun 28; Vol. 50 (13), pp. 3037-45. Date of Electronic Publication: 2007 Jun 01.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antiviral Agents/*chemical synthesis
Cytostatic Agents/*chemical synthesis
Pyrimidines/*chemical synthesis
Animals ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Cell Line ; Cell Line, Tumor ; Chlorocebus aethiops ; Cytostatic Agents/chemistry ; Cytostatic Agents/pharmacology ; Drug Screening Assays, Antitumor ; Humans ; Magnetic Resonance Spectroscopy ; Mice ; Models, Molecular ; Molecular Conformation ; Molecular Mimicry ; Positron-Emission Tomography ; Pyrimidine Nucleosides/chemistry ; Pyrimidines/chemistry ; Pyrimidines/pharmacology ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 16 16.

Tytuł :: The novel C-5 aryl, alkenyl, and alkynyl substituted uracil derivatives of L-ascorbic acid: synthesis, cytostatic, and antiviral activity evaluations.
Autorzy :: Gazivoda T; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Raić-Malić S
Marjanović M
Kralj M
Pavelić K
Balzarini J
De Clercq E
Mintas M; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2007 Jan 15; Vol. 15 (2), pp. 749-58. Date of Electronic Publication: 2006 Oct 25.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Antiviral Agents/*chemical synthesis
Antiviral Agents/*pharmacology
Ascorbic Acid/*analogs & derivatives
Ascorbic Acid/*chemical synthesis
Uracil/*chemistry
Animals ; Ascorbic Acid/pharmacology ; Cell Line, Tumor ; Drug Evaluation, Preclinical ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; Humans ; Indicators and Reagents ; Magnetic Resonance Spectroscopy ; Mass Spectrometry ; Mice ; Pyrimidines/chemistry ; Structure-Activity Relationship ; Viruses/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 17 17.

Tytuł :: Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues.
Autorzy :: Kristafor V; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, 10000 Zagreb, Croatia.
Raić-Malić S
Cetina M
Kralj M
Suman L
Pavelić K
Balzarini J
De Clercq E
Mintas M; Pokaż więcej
Źródło :: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2006 Dec 01; Vol. 14 (23), pp. 8126-38. Date of Electronic Publication: 2006 Aug 02.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemistry
Antiviral Agents/*chemistry
Nucleosides/*chemical synthesis
Nucleosides/*pharmacology
Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/pharmacology ; Antiviral Agents/chemical synthesis ; Antiviral Agents/pharmacology ; Cell Proliferation/drug effects ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/pathology ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Epoxy Compounds ; HIV-1/drug effects ; Humans ; Isomerism ; Molecular Structure ; Structure-Activity Relationship
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 18 18.

Tytuł :: Hydantoin derivatives of L- and D-amino acids: synthesis and evaluation of their antiviral and antitumoral activity.
Autorzy :: Rajic Z; Department of Medicinal Chemistry, Faculty of Pharmacy and Biochemistry, A. Kovacića 1, HR-10000 Zagreb, Croatia. />Zorc B
Raic-Malic S
Ester K
Kralj M
Pavelic K
Balzarini J
De Clercq E
Mintas M; Pokaż więcej
Źródło :: Molecules (Basel, Switzerland) [Molecules] 2006 Nov 01; Vol. 11 (11), pp. 837-48. Date of Electronic Publication: 2006 Nov 01.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Amino Acids/*chemical synthesis
Amino Acids/*pharmacology
Antineoplastic Agents/*pharmacology
Antiviral Agents/*pharmacology
Hydantoins/*chemical synthesis
Hydantoins/*pharmacology
Amino Acids/chemistry ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Antiviral Agents/chemical synthesis ; Antiviral Agents/chemistry ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Fibroblasts/drug effects ; Humans ; Hydantoins/chemistry ; Magnetic Resonance Spectroscopy ; Viruses/drug effects
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 19 19.

Tytuł :: Synthesis, structural studies, and cytostatic evaluation of 5,6-di-O-modified L-ascorbic acid derivatives.
Autorzy :: Gazivoda T; Department of Organic Chemistry, Faculty of Chemical Engineering and Technology, University of Zagreb, Marulićev trg 19, HR-10000 Zagreb, Croatia.
Wittine K
Lovrić I
Makuc D
Plavec J
Cetina M
Mrvos-Sermek D
Suman L
Kralj M
Pavelić K
Mintas M
Raić-Malić S; Pokaż więcej
Źródło :: Carbohydrate research [Carbohydr Res] 2006 Mar 20; Vol. 341 (4), pp. 433-42. Date of Electronic Publication: 2006 Jan 24.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Antineoplastic Agents/*chemical synthesis
Antineoplastic Agents/*pharmacology
Ascorbic Acid/*chemical synthesis
Ascorbic Acid/*pharmacology
Antineoplastic Agents/chemistry ; Ascorbic Acid/analogs & derivatives ; Carbohydrate Conformation ; Cell Line, Tumor ; Crystallography, X-Ray ; Drug Screening Assays, Antitumor ; Humans ; Magnetic Resonance Spectroscopy ; Models, Molecular ; Molecular Conformation ; Molecular Structure
: Czasopismo naukowe

Szczegóły

Skocz do pozycji: 20 20.

Tytuł :: Hydrogen-bonding and C-H...pi interactions in 7-hydroxy-3-methoxy-4-methyl-5,6,7,8-tetrahydropyrido[1,2-c]pyrimidin-1(9H)-one.
Autorzy :: Cetina M; Faculty of Textile Technology, University of Zagreb, Pierottijeva 6, HR-10000 Zagreb, Croatia. />Nagl A
Prekupec S
Raić-Malić S
Mintas M; Pokaż więcej
Źródło :: Acta crystallographica. Section C, Crystal structure communications [Acta Crystallogr C] 2005 Mar; Vol. 61 (Pt 3), pp. o158-60. Date of Electronic Publication: 2005 Feb 19.
Typ publikacji :: Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :: Piperidines/*chemistry
Pyrimidinones/*chemistry
Antineoplastic Agents/chemistry ; Antiviral Agents/chemistry ; Crystallography, X-Ray ; Hydrogen Bonding ; Molecular Structure
: Czasopismo naukowe

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Prolib Integro - strona głównaUniwersytet Ekonomiczny we Wrocławiu

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