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Wyświetlanie 1-8 z 8
Tytuł :
The USTC co-opts an ancient machinery to drive piRNA transcription in C. elegans .
Autorzy :
Weng C; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Kosalka J; Wellcome Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Berkyurek AC; Wellcome Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Stempor P; Wellcome Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Feng X; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Mao H; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Zeng C; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Li WJ; National Institute of Biological Sciences, Beijing 102206, China.
Yan YH; National Institute of Biological Sciences, Beijing 102206, China.
Dong MQ; National Institute of Biological Sciences, Beijing 102206, China.
Morero NR; Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Zuliani C; Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Barabas O; Structural and Computational Biology Unit, European Molecular Biology Laboratory (EMBL), 69117 Heidelberg, Germany.
Ahringer J; Wellcome Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.
Guang S; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Miska EA; Wellcome Cancer Research UK Gurdon Institute, University of Cambridge, Cambridge CB2 1QN, United Kingdom; Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom.; Wellcome Sanger Institute, Cambridge CB10 1SA, United Kingdom.
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Źródło :
Genes & development [Genes Dev] 2019 Jan 01; Vol. 33 (1-2), pp. 90-102. Date of Electronic Publication: 2018 Dec 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Caenorhabditis elegans/*genetics
Caenorhabditis elegans/*metabolism
Caenorhabditis elegans Proteins/*metabolism
Gene Expression Regulation/*genetics
RNA, Small Interfering/*genetics
Amino Acid Motifs ; Animals ; Caenorhabditis elegans Proteins/genetics ; Genome, Helminth/genetics ; Protein Binding ; Proteomics ; RNA, Small Interfering/biosynthesis
Czasopismo naukowe
Tytuł :
A team of heterochromatin factors collaborates with small RNA pathways to combat repetitive elements and germline stress.
Autorzy :
McMurchy AN; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Stempor P; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Gaarenstroom T; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Wysolmerski B; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Dong Y; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Aussianikava D; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Appert A; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Huang N; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Kolasinska-Zwierz P; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Sapetschnig A; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Miska EA; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
Ahringer J; The Gurdon Institute and Department of Genetics, University of Cambridge, Cambridge, United Kingdom.
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Źródło :
ELife [Elife] 2017 Mar 15; Vol. 6. Date of Electronic Publication: 2017 Mar 15.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Interspersed Repetitive Sequences*
Caenorhabditis elegans/*genetics
Chromosomal Proteins, Non-Histone/*metabolism
Heterochromatin/*metabolism
RNA, Small Interfering/*metabolism
Animals ; Apoptosis ; Caenorhabditis elegans Proteins/metabolism ; DNA Repair ; Germ Cells/physiology ; RNA Interference
Czasopismo naukowe
Tytuł :
piRNAs: from biogenesis to function.
Autorzy :
Weick EM; Wellcome Trust Cancer Research UK Gurdon Institute, Department of Biochemistry and Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.
Miska EA; Wellcome Trust Cancer Research UK Gurdon Institute, Department of Biochemistry and Department of Genetics, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK e.miska@gurdon.cam.ac.uk.
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Źródło :
Development (Cambridge, England) [Development] 2014 Sep; Vol. 141 (18), pp. 3458-71.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Models, Genetic*
Epigenesis, Genetic/*genetics
Gene Expression Regulation/*genetics
Germ-Line Mutation/*genetics
RNA, Small Interfering/*biosynthesis
RNA, Small Interfering/*metabolism
Animals
Czasopismo naukowe
Tytuł :
The microRNA miR-124 controls gene expression in the sensory nervous system of Caenorhabditis elegans.
Autorzy :
Clark AM; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, The Henry Wellcome Building of Cancer and Developmental Biology, Tennis Court Rd, Cambridge CB2 1QN, UK.
Goldstein LD
Tevlin M
Tavaré S
Shaham S
Miska EA
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Źródło :
Nucleic acids research [Nucleic Acids Res] 2010 Jun; Vol. 38 (11), pp. 3780-93. Date of Electronic Publication: 2010 Feb 21.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Caenorhabditis elegans/*genetics
MicroRNAs/*metabolism
Sensory Receptor Cells/*metabolism
Animals ; Caenorhabditis elegans/embryology ; Caenorhabditis elegans/metabolism ; Cells, Cultured ; Gene Deletion ; Gene Expression Profiling ; MicroRNAs/genetics ; Nervous System/cytology ; Nervous System/embryology ; Nervous System/growth & development
Czasopismo naukowe
Tytuł :
LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans.
Autorzy :
Lehrbach NJ; Wellcome Trust Cancer Research UK Gurdon Institute, University of Cambridge, The Henry Wellcome Building of Cancer and Developmental Biology, Cambridge, UK.
Armisen J
Lightfoot HL
Murfitt KJ
Bugaut A
Balasubramanian S
Miska EA
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Źródło :
Nature structural & molecular biology [Nat Struct Mol Biol] 2009 Oct; Vol. 16 (10), pp. 1016-20. Date of Electronic Publication: 2009 Aug 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Caenorhabditis elegans Proteins/*genetics
Caenorhabditis elegans Proteins/*physiology
MicroRNAs/*genetics
Nucleotidyltransferases/*physiology
Repressor Proteins/*genetics
Repressor Proteins/*physiology
Animals ; Animals, Genetically Modified ; Base Sequence ; Caenorhabditis elegans ; Cell Differentiation ; MicroRNAs/metabolism ; Models, Biological ; Molecular Sequence Data ; Nucleotidyltransferases/metabolism ; RNA Processing, Post-Transcriptional ; Ribonuclease III/metabolism ; Sequence Homology, Nucleic Acid
Czasopismo naukowe
Tytuł :
MicroRNA expression profiling of human breast cancer identifies new markers of tumor subtype.
Autorzy :
Blenkiron C; Cancer Research UK, Cambridge Research Institute, Li Ka-Shing Centre, Robinson Way, Cambridge CB2 0RE, UK. />Goldstein LD
Thorne NP
Spiteri I
Chin SF
Dunning MJ
Barbosa-Morais NL
Teschendorff AE
Green AR
Ellis IO
Tavaré S
Caldas C
Miska EA
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Źródło :
Genome biology [Genome Biol] 2007; Vol. 8 (10), pp. R214.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Gene Expression Regulation*
Breast Neoplasms/*metabolism
Gene Expression Profiling/*methods
Mammary Glands, Human/*metabolism
MicroRNAs/*metabolism
RNA, Messenger/*metabolism
Argonaute Proteins ; Breast Neoplasms/classification ; DEAD-box RNA Helicases/metabolism ; DNA Primers ; Endoribonucleases/metabolism ; Eukaryotic Initiation Factor-2/metabolism ; Female ; Flow Cytometry ; Humans ; MicroRNAs/genetics ; Ribonuclease III
Czasopismo naukowe
Tytuł :
Regulation of gene expression by transcription factor acetylation.
Autorzy :
Bannister AJ; Wellcome/CRC Institute and Department of Pathology, University of Cambridge, United Kingdom. />Miska EA
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2000 Aug; Vol. 57 (8-9), pp. 1184-92.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Gene Expression Regulation*
Saccharomyces cerevisiae Proteins*
Histones/*metabolism
Transcription Factors/*metabolism
Acetylation ; Acetyltransferases/metabolism ; Amino Acid Sequence ; Animals ; Histone Acetyltransferases ; Histones/chemistry ; Humans ; Molecular Sequence Data ; Nucleosomes/genetics ; Nucleosomes/ultrastructure
Czasopismo naukowe
Tytuł :
Retinoblastoma protein recruits histone deacetylase to repress transcription.
Autorzy :
Brehm A; Wellcome/CRC Institute and Department of Pathology, University of Cambridge, UK.
Miska EA
McCance DJ
Reid JL
Bannister AJ
Kouzarides T
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Źródło :
Nature [Nature] 1998 Feb 05; Vol. 391 (6667), pp. 597-601.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Carrier Proteins*
Cell Cycle Proteins*
DNA-Binding Proteins*
Gene Expression Regulation*
Transcription, Genetic*
Histone Deacetylases/*metabolism
Retinoblastoma Protein/*physiology
Amino Acid Sequence ; Binding Sites ; Cell Line ; Cyclin E/genetics ; E2F Transcription Factors ; HeLa Cells ; Histone Deacetylase 1 ; Humans ; Molecular Sequence Data ; Protein Binding ; Retinoblastoma-Binding Protein 1 ; Transcription Factor DP1 ; Transcription Factors/antagonists & inhibitors ; Transcription Factors/metabolism
Czasopismo naukowe
    Wyświetlanie 1-8 z 8

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