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    Wyświetlanie 1-11 z 11
    Tytuł:
    Response and Resistance to Trametinib in MAP2K1-Mutant Triple-Negative Melanoma.
    Autorzy:
    Krebs FS; Computer-Aided Molecular Engineering, Department of Oncology UNIL-CHUV, University of Lausanne, 1015 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.
    Moura B; Service of Medical Oncology, 1700 Fribourg, Switzerland.
    Missiaglia E; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
    Aedo-Lopez V; Monash Medical Centre, Clayton, VIC 3168, Australia.
    Michielin O; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Centre for Personalized Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.; Department of Oncology, Hopitaux Universitaire de Genève, 1205 Geneva, Switzerland.
    Tsantoulis P; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.; Department of Oncology, Hopitaux Universitaire de Genève, 1205 Geneva, Switzerland.
    Bisig B; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.
    Trimech M; Department of Laboratory Medicine and Pathology, Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne University, 1011 Lausanne, Switzerland.
    Zoete V; Computer-Aided Molecular Engineering, Department of Oncology UNIL-CHUV, University of Lausanne, 1015 Lausanne, Switzerland.; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.; Molecular Modelling Group, SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.
    Homicsko K; Ludwig Institute for Cancer Research, 1005 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Centre for Personalized Oncology, Department of Oncology, Centre Hospitalier Universitaire Vaudois, 1011 Lausanne, Switzerland.; Swiss Cancer Center Leman, 1005 Lausanne, Switzerland.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2023 Feb 24; Vol. 24 (5). Date of Electronic Publication: 2023 Feb 24.
    Typ publikacji:
    Case Reports
    MeSH Terms:
    Skin Neoplasms*/genetics
    Melanoma*/genetics
    Male ; Humans ; Pyridones/therapeutic use ; Pyrimidinones/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Mitogen-Activated Protein Kinase Kinases/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Mutation ; MAP Kinase Kinase 1/genetics
    Raport
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma in Asia Frequently Shows SETD2 Alterations.
    Autorzy:
    Tomita S; Department of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
    Kikuti YY; Department of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
    Carreras J; Department of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
    Sakai R; Department of Oncology, Kanagawa Cancer Center, Kanagawa, Yokohama 241-8515, Japan.
    Takata K; Department of Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
    Yoshino T; Department of Pathology, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University, Okayama 700-8558, Japan.
    Bea S; Department of Pathology, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), University of Barcelona, Rossello 149-153, 08036 Barcelona, Spain.
    Campo E; Department of Pathology, Hospital Clinic Barcelona, Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Centro de Investigacion Biomedica en Red de Cancer (CIBERONC), University of Barcelona, Rossello 149-153, 08036 Barcelona, Spain.
    Missiaglia E; Institute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
    Bouilly J; Institute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
    Letourneau A; Institute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
    de Leval L; Institute of Pathology, Lausanne University Hospital, Lausanne University, Vaud, 1015 Lausanne, Switzerland.
    Nakamura N; Department of Pathology, School of Medicine, Tokai University, 143 Shimokasuya, Kanagawa, Isehara 259-1193, Japan.
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    Źródło:
    Cancers [Cancers (Basel)] 2020 Nov 27; Vol. 12 (12). Date of Electronic Publication: 2020 Nov 27.
    Typ publikacji:
    Journal Article
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    Trametinib Induces the Stabilization of a Dual GNAQ p.Gly48Leu- and FGFR4 p.Cys172Gly-Mutated Uveal Melanoma. The Role of Molecular Modelling in Personalized Oncology.
    Autorzy:
    Krebs FS; Computer-aided molecular engineering group, Department of Fundamental Oncology, Lausanne University, Ludwig Lausanne Branch, 1066 Epalinges, Switzerland.
    Gérard C; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Wicky A; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Aedo-Lopez V; Service of Medical Oncology, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Missiaglia E; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Bisig B; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Trimech M; University Institute of Pathology, Lausanne University Hospital, 1011 Lausanne, Switzerland.
    Michielin O; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; Service of Medical Oncology, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
    Homicsko K; Precision Oncology Center, Department of Oncology, Lausanne University Hospital, 1011 Lausanne, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.; Laboratory of Translational Oncology, EPFL, 1015 Lausanne, Switzerland.
    Zoete V; Computer-aided molecular engineering group, Department of Fundamental Oncology, Lausanne University, Ludwig Lausanne Branch, 1066 Epalinges, Switzerland.; SIB Swiss Institute of Bioinformatics, 1015 Lausanne, Switzerland.
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    Źródło:
    International journal of molecular sciences [Int J Mol Sci] 2020 Oct 28; Vol. 21 (21). Date of Electronic Publication: 2020 Oct 28.
    Typ publikacji:
    Case Reports; Journal Article
    MeSH Terms:
    Mutation*
    GTP-Binding Protein alpha Subunits, Gq-G11/*chemistry
    Melanoma/*drug therapy
    Melanoma/*genetics
    Mutant Proteins/*chemistry
    Pyridones/*therapeutic use
    Pyrimidinones/*therapeutic use
    Receptor, Fibroblast Growth Factor, Type 4/*chemistry
    Uveal Neoplasms/*drug therapy
    Uveal Neoplasms/*genetics
    Amino Acid Sequence ; Antineoplastic Agents/therapeutic use ; Female ; GTP-Binding Protein alpha Subunits, Gq-G11/genetics ; GTP-Binding Protein alpha Subunits, Gq-G11/metabolism ; Humans ; Melanoma/metabolism ; Melanoma/pathology ; Middle Aged ; Models, Molecular ; Mutant Proteins/genetics ; Mutant Proteins/metabolism ; Protein Conformation ; Protein Stability ; Receptor, Fibroblast Growth Factor, Type 4/genetics ; Receptor, Fibroblast Growth Factor, Type 4/metabolism ; Sequence Homology ; Signal Transduction ; Uveal Neoplasms/metabolism ; Uveal Neoplasms/pathology
    SCR Disease Name:
    Uveal melanoma
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknie Pełny tekstSzczegóły
    Tytuł:
    The consensus molecular subtypes of colorectal cancer.
    Autorzy:
    Guinney J; Sage Bionetworks, Seattle, Washington, USA.
    Dienstmann R; Sage Bionetworks, Seattle, Washington, USA.; Vall d'Hebron Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
    Wang X; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.; Department of Biomedical Sciences, City University of Hong Kong, Hong Kong.
    de Reyniès A; Ligue Nationale Contre le Cancer, Paris, France.
    Schlicker A; Netherlands Cancer Institute (NKI), Amsterdam, the Netherlands.
    Soneson C; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Marisa L; Ligue Nationale Contre le Cancer, Paris, France.
    Roepman P; Agendia NV, Amsterdam, the Netherlands.
    Nyamundanda G; Institute of Cancer Research, London, UK.
    Angelino P; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Bot BM; Sage Bionetworks, Seattle, Washington, USA.
    Morris JS; The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA.
    Simon IM; Agendia NV, Amsterdam, the Netherlands.
    Gerster S; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Fessler E; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.
    De Sousa E Melo F; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.
    Missiaglia E; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Ramay H; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Barras D; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.
    Homicsko K; École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
    Maru D; The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA.
    Manyam GC; The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA.
    Broom B; The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA.
    Boige V; Gustave Roussy, Villejuif, France.
    Perez-Villamil B; Laboratorio de Genomica y Microarrays, Instituto de Investigación Sanitaria San Carlos, Hospital Clinico San Carlos, Madrid, Spain.
    Laderas T; Sage Bionetworks, Seattle, Washington, USA.
    Salazar R; Institut Catala d'Oncologia, L'Institut d'Investigació Biomèdica de Bellvitge, Barcelona, Spain.
    Gray JW; Biomedical Engineering, Oregon Health Sciences University, Portland, Oregon, USA.
    Hanahan D; École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.
    Tabernero J; Vall d'Hebron Institute of Oncology (VHIO), Universitat Autònoma de Barcelona, Barcelona, Spain.
    Bernards R; Netherlands Cancer Institute (NKI), Amsterdam, the Netherlands.
    Friend SH; Sage Bionetworks, Seattle, Washington, USA.
    Laurent-Puig P; Université Paris Descartes, Paris, France.; Department of Biology, Hôpital Européen Georges-Pompidou, Assistance Publique - Hôpitaux de Paris, Paris, France.
    Medema JP; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.
    Sadanandam A; Institute of Cancer Research, London, UK.
    Wessels L; Netherlands Cancer Institute (NKI), Amsterdam, the Netherlands.
    Delorenzi M; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland.; Ludwig Center for Cancer Research, University of Lausanne, Lausanne, Switzerland.; Department of Oncology, University of Lausanne, Lausanne, Switzerland.
    Kopetz S; The University of Texas, M.D. Anderson Cancer Center, Houston, Texas, USA.
    Vermeulen L; Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, the Netherlands.
    Tejpar S; Universitair ziekenhuis Leuven, Leuven, Belgium.
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    Źródło:
    Nature medicine [Nat Med] 2015 Nov; Vol. 21 (11), pp. 1350-6. Date of Electronic Publication: 2015 Oct 12.
    Typ publikacji:
    Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Expression Regulation, Neoplastic*
    Carcinoma/*genetics
    Colorectal Neoplasms/*genetics
    Neovascularization, Pathologic/*genetics
    Transforming Growth Factor beta/*genetics
    Carcinoma/classification ; Carcinoma/pathology ; Colorectal Neoplasms/classification ; Colorectal Neoplasms/pathology ; Consensus ; CpG Islands ; DNA Copy Number Variations/genetics ; DNA Methylation ; Gene Expression Profiling ; Genes, myc/genetics ; Humans ; Information Dissemination ; Microsatellite Instability ; Mutation/genetics ; Neovascularization, Pathologic/pathology ; Phenotype ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins B-raf/genetics ; Proto-Oncogene Proteins p21(ras) ; Wnt Signaling Pathway/genetics ; ras Proteins/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells.
    Autorzy:
    Walters ZS; Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK.
    Villarejo-Balcells B; Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK.
    Olmos D; 1] Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK [2] Sarcoma Unit, Royal Marsden Hospital NHS Trust, London, UK.
    Buist TW; 1] Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK [2] Computational Biology and Chemogenomics, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, Institute of Cancer Research, Sutton, London, UK.
    Missiaglia E; 1] Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK [2] Swiss Institute of Bioinformatics, Bioinformatics Core Facility, University of Lausanne, Lausanne, Switzerland.
    Allen R; Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK.
    Al-Lazikani B; Computational Biology and Chemogenomics, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, Institute of Cancer Research, Sutton, London, UK.
    Garrett MD; Cell Cycle Control Team, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK.
    Blagg J; Medicinal Chemistry, Cancer Research UK Cancer Therapeutics Unit, Division of Cancer Therapeutics, The Institute of Cancer Research, Sutton, London, UK.
    Shipley J; Sarcoma Molecular Pathology Team, Divisions of Molecular Pathology and Cancer Therapeutics, The Institute of Cancer Research, Sutton, Surrey, London, UK.
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    Źródło:
    Oncogene [Oncogene] 2014 Feb 27; Vol. 33 (9), pp. 1148-57. Date of Electronic Publication: 2013 Feb 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Cell Differentiation/*genetics
    Muscle Development/*genetics
    Oncogene Proteins, Fusion/*genetics
    Paired Box Transcription Factors/*genetics
    Polycomb Repressive Complex 2/*genetics
    Rhabdomyosarcoma/*genetics
    Cell Line, Tumor ; Cell Proliferation ; Enhancer of Zeste Homolog 2 Protein ; Gene Expression Regulation, Neoplastic/genetics ; Histone Demethylases/genetics ; Histone Demethylases/metabolism ; Humans ; Myogenin/genetics ; Myogenin/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Oncogene Proteins, Fusion/metabolism ; Paired Box Transcription Factors/metabolism ; Polycomb Repressive Complex 2/metabolism ; Promoter Regions, Genetic/genetics ; Promyelocytic Leukemia Protein ; Rhabdomyosarcoma/pathology ; Transcription Factors/genetics ; Transcription Factors/metabolism ; Transcription, Genetic/genetics ; Tumor Suppressor Proteins/genetics ; Tumor Suppressor Proteins/metabolism
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells.
    Autorzy:
    Carrascosa C; Division of Experimental Oncology, Centre Pluridisciplinaire d'Oncologie, Lausanne Cancer Center, University of Lausanne, Epalinges, Switzerland.
    Obula RG
    Missiaglia E
    Lehr HA
    Delorenzi M
    Frattini M
    Rüegg C
    Mariotti A
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    Źródło:
    Oncogene [Oncogene] 2012 Mar 22; Vol. 31 (12), pp. 1521-32. Date of Electronic Publication: 2011 Aug 15.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Antigens, Surface/*physiology
    Cyclin D1/*metabolism
    Cyclin D3/*metabolism
    Epithelial Cells/*metabolism
    Mammary Neoplasms, Experimental/*metabolism
    Animals ; Breast/metabolism ; Cadherins/metabolism ; Cell Line ; Cell Proliferation ; Epithelial-Mesenchymal Transition ; Female ; Gene Expression Regulation, Neoplastic ; Humans ; Mice ; Mice, SCID ; Milk Proteins ; Neoplasm Transplantation ; Signal Transduction/physiology
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Activation of the hedgehog pathway confers a poor prognosis in embryonal and fusion gene-negative alveolar rhabdomyosarcoma.
    Autorzy:
    Zibat A; Institute of Human Genetics, University of Goettingen, Goettingen, Germany.
    Missiaglia E
    Rosenberger A
    Pritchard-Jones K
    Shipley J
    Hahn H
    Fulda S
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    Źródło:
    Oncogene [Oncogene] 2010 Dec 02; Vol. 29 (48), pp. 6323-30. Date of Electronic Publication: 2010 Sep 06.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Hedgehog Proteins/*physiology
    Rhabdomyosarcoma, Alveolar/*metabolism
    Rhabdomyosarcoma, Embryonal/*metabolism
    Signal Transduction/*physiology
    Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Gene Fusion ; Humans ; Infant ; Kruppel-Like Transcription Factors/analysis ; Male ; Myogenic Regulatory Factor 5/analysis ; Nerve Tissue Proteins/analysis ; Patched Receptors ; Patched-1 Receptor ; Prognosis ; Receptors, Cell Surface/analysis ; Rhabdomyosarcoma, Alveolar/mortality ; Rhabdomyosarcoma, Embryonal/mortality ; Transcription Factors/analysis ; Zinc Finger Protein GLI1 ; Zinc Finger Protein Gli3
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    MicroRNA-206 expression levels correlate with clinical behaviour of rhabdomyosarcomas.
    Autorzy:
    Missiaglia E; Molecular Cytogenetics Team, The Institute of Cancer Research, Sutton, Surrey SM2 5NG, UK.
    Shepherd CJ
    Patel S
    Thway K
    Pierron G
    Pritchard-Jones K
    Renard M
    Sciot R
    Rao P
    Oberlin O
    Delattre O
    Shipley J
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    Źródło:
    British journal of cancer [Br J Cancer] 2010 Jun 08; Vol. 102 (12), pp. 1769-77. Date of Electronic Publication: 2010 May 25.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    MicroRNAs/*metabolism
    Rhabdomyosarcoma/*genetics
    Adolescent ; Adult ; Cell Differentiation ; Cell Line, Tumor ; Child ; Child, Preschool ; Female ; Gene Expression Profiling ; Humans ; Infant ; Male ; Muscle, Skeletal/metabolism ; Rhabdomyosarcoma/mortality ; Transfection ; Tumor Suppressor Proteins
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Genomic copy number and expression patterns in testicular germ cell tumours.
    Autorzy:
    McIntyre A; Molecular Cytogenetics, Section of Molecular Carcinogenesis, The Institute of Cancer Research, Sutton, Surrey, UK.
    Summersgill B
    Lu YJ
    Missiaglia E
    Kitazawa S
    Oosterhuis JW
    Looijenga LH
    Shipley J
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    Źródło:
    British journal of cancer [Br J Cancer] 2007 Dec 17; Vol. 97 (12), pp. 1707-12. Date of Electronic Publication: 2007 Dec 04.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Gene Dosage*
    Gene Expression Profiling*
    Neoplasms, Germ Cell and Embryonal/*genetics
    Testicular Neoplasms/*genetics
    Cell Line, Tumor ; Genome ; Humans ; Male ; Nucleic Acid Hybridization
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Growth delay of human pancreatic cancer cells by methylase inhibitor 5-aza-2'-deoxycytidine treatment is associated with activation of the interferon signalling pathway.
    Autorzy:
    Missiaglia E; Cancer Research UK, Molecular Oncology Unit, Imperial College School of Medicine at Hammersmith Campus, London, UK.
    Donadelli M
    Palmieri M
    Crnogorac-Jurcevic T
    Scarpa A
    Lemoine NR
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    Źródło:
    Oncogene [Oncogene] 2005 Jan 06; Vol. 24 (1), pp. 199-211.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't
    MeSH Terms:
    Azacitidine/*analogs & derivatives
    Azacitidine/*pharmacology
    DNA Modification Methylases/*antagonists & inhibitors
    Deoxycytidine/*analogs & derivatives
    Interferons/*metabolism
    Pancreatic Neoplasms/*drug therapy
    Signal Transduction/*drug effects
    Antimetabolites, Antineoplastic/pharmacology ; Antineoplastic Agents/pharmacology ; Cisplatin/pharmacology ; DNA Methylation/drug effects ; Decitabine ; Deoxycytidine/pharmacology ; Gene Expression Profiling ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Interferon-gamma/pharmacology ; Pancreatic Neoplasms/enzymology ; Gemcitabine
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
    Tytuł:
    Prime-boost vaccines encoding an intracellular idiotype/GM-CSF fusion protein induce protective cell-mediated immunity in murine pre-B cell leukemia.
    Autorzy:
    Pasquini S; ICRF Molecular Oncology Unit, Imperial College School of Medicine, Hammersmith Hospital, London, UK.
    Peralta S
    Missiaglia E
    Carta L
    Lemoine NR
    Pokaż więcej
    Źródło:
    Gene therapy [Gene Ther] 2002 Apr; Vol. 9 (8), pp. 503-10.
    Typ publikacji:
    Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
    MeSH Terms:
    Complementarity Determining Regions/*genetics
    Granulocyte-Macrophage Colony-Stimulating Factor/*genetics
    Immunoglobulin Heavy Chains/*genetics
    Neoplasm, Residual/*therapy
    Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/*therapy
    Vaccines, DNA/*administration & dosage
    Animals ; Base Sequence ; CD4-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/immunology ; Female ; Genetic Engineering ; Genetic Vectors/administration & dosage ; Mice ; Mice, Inbred Strains ; Molecular Sequence Data ; Plasmids ; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma/immunology ; Recombinant Fusion Proteins/genetics ; Vaccinia/genetics
    Czasopismo naukowe
    Pełny tekst  Link otwiera się w nowym oknieSzczegóły
      Wyświetlanie 1-11 z 11

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