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Wyszukujesz frazę ""Mitochondria"" wg kryterium: Temat


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Tytuł :
The influence of aerobic exercise on mitochondrial quality control in skeletal muscle.
Autorzy :
Philp AM; Healthy Ageing Research Theme, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, New South Wales, 2010, Australia.; St Vincent's Medical School, UNSW Medicine, UNSW Sydney, Sydney, New South Wales, 2010, Australia.
Saner NJ; Sports Cardiology, Baker Heart and Diabetes Institute, Melbourne, Australia.
Lazarou M; Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.
Ganley IG; Medical Research Council Protein Phosphorylation and Ubiquitylation Unit, School of Life Sciences, University of Dundee, Dundee, UK.
Philp A; Healthy Ageing Research Theme, Garvan Institute of Medical Research, 384 Victoria Street, Sydney, New South Wales, 2010, Australia.; St Vincent's Medical School, UNSW Medicine, UNSW Sydney, Sydney, New South Wales, 2010, Australia.
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Źródło :
The Journal of physiology [J Physiol] 2021 Jul; Vol. 599 (14), pp. 3463-3476. Date of Electronic Publication: 2021 Jan 06.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitochondria*
Mitophagy*
Exercise ; Humans ; Mitochondria, Muscle/metabolism ; Muscle, Skeletal ; Organelle Biogenesis
Czasopismo naukowe
Tytuł :
Mitochondria-targeted prooxidant effects of betulinic acid conjugated with delocalized lipophilic cation F16.
Autorzy :
Dubinin MV; Mari State University, Pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia. Electronic address: .
Semenova AA; Mari State University, Pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia.
Ilzorkina AI; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia.
Penkov NV; Institute of Cell Biophysics, Russian Academy of Sciences, PSCBR RAS, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia.
Nedopekina DA; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia.
Sharapov VA; Mari State University, Pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia.
Khoroshavina EI; Mari State University, Pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia.
Davletshin EV; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia.
Belosludtseva NV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia.
Spivak AY; Institute of Petrochemistry and Catalysis, Russian Academy of Sciences, Prospekt Oktyabrya 141, Ufa, Republic of Bashkortostan, 450075, Russia.
Belosludtsev KN; Mari State University, Pl. Lenina 1, Yoshkar-Ola, Mari El, 424001, Russia; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Institutskaya 3, Pushchino, Moscow Region, 142290, Russia; Prokhorov General Physics Institute of the Russian Academy of Sciences, Vavilova 38, Moscow, 119991, Russia.
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Źródło :
Free radical biology & medicine [Free Radic Biol Med] 2021 May 20; Vol. 168, pp. 55-69. Date of Electronic Publication: 2021 Apr 01.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitochondria*
Triterpenes*/metabolism
Animals ; Cations/metabolism ; Mitochondria, Liver/metabolism ; Pentacyclic Triterpenes ; Rats ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Mitochondria-associated membrane-modulated Ca transfer: A potential treatment target in cardiac ischemia reperfusion injury and heart failure.
Autorzy :
Gong Y; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China.
Lin J; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China.
Ma Z; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China.
Yu M; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China.
Wang M; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China. Electronic address: .
Lai D; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China. Electronic address: .
Fu G; Department of Cardiology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China; Key Laboratory of Cardiovascular Intervention and Regenerative Medicine of Zhejiang Province, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Aug 01; Vol. 278, pp. 119511. Date of Electronic Publication: 2021 Apr 14.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Calcium/*metabolism
Heart Failure/*metabolism
Mitochondria/*metabolism
Myocardial Ischemia/*metabolism
Reperfusion Injury/*metabolism
Animals ; Calcium Signaling ; Cell Line ; Endoplasmic Reticulum/metabolism ; Endoplasmic Reticulum Stress ; Homeostasis ; Humans ; Mice ; Mitochondria, Heart/metabolism ; Mitochondrial Membranes/metabolism ; Myocardial Contraction ; Myocardial Reperfusion Injury/metabolism ; Myocytes, Cardiac/metabolism ; Treatment Outcome
Czasopismo naukowe
Tytuł :
Exercise and mitochondrial health.
Autorzy :
Memme JM; Muscle Health Research Centre, York University, Toronto, Ontario, Canada, M3J 1P3.; School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada, M3J 1P3.
Erlich AT; Muscle Health Research Centre, York University, Toronto, Ontario, Canada, M3J 1P3.; School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada, M3J 1P3.
Phukan G; Muscle Health Research Centre, York University, Toronto, Ontario, Canada, M3J 1P3.; School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada, M3J 1P3.
Hood DA; Muscle Health Research Centre, York University, Toronto, Ontario, Canada, M3J 1P3.; School of Kinesiology and Health Science, York University, Toronto, Ontario, Canada, M3J 1P3.
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Źródło :
The Journal of physiology [J Physiol] 2021 Feb; Vol. 599 (3), pp. 803-817. Date of Electronic Publication: 2019 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Exercise*
Mitochondria, Muscle*/metabolism
Humans ; Mitochondria ; Mitophagy ; Muscle, Skeletal/metabolism ; Organelle Biogenesis
Czasopismo naukowe
Tytuł :
Mitochondria Matter: Systemic Aspects of Nonalcoholic Fatty Liver Disease (NAFLD) and Diagnostic Assessment of Liver Function by Stable Isotope Dynamic Breath Tests.
Autorzy :
Di Ciaula A; Clinica Medica 'A. Murri', Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.
Calamita G; Department of Biosciences, Biotechnologies and Biopharmaceutics, University of Bari 'Aldo Moro', 70100 Bari, Italy.
Shanmugam H; Clinica Medica 'A. Murri', Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.
Khalil M; Clinica Medica 'A. Murri', Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.
Bonfrate L; Clinica Medica 'A. Murri', Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.
Wang DQ; Marion Bessin Liver Research Center, Einstein-Mount Sinai Diabetes Research Center, Department of Medicine and Genetics, Division of Gastroenterology and Liver Diseases, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Baffy G; Department of Medicine, VA Boston Healthcare System and Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02130, USA.
Portincasa P; Clinica Medica 'A. Murri', Department of Biomedical Sciences & Human Oncology, University of Bari Medical School, 70124 Bari, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 19; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 19.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Breath Tests/*methods
Mitochondria/*metabolism
Non-alcoholic Fatty Liver Disease/*metabolism
Biomarkers/metabolism ; Carcinoma, Hepatocellular/metabolism ; Hepatocytes/metabolism ; Humans ; Liver/pathology ; Liver/physiopathology ; Liver Cirrhosis/metabolism ; Liver Function Tests ; Liver Neoplasms/metabolism ; Mitochondria/pathology ; Mitochondria, Liver/metabolism ; Non-alcoholic Fatty Liver Disease/pathology ; Non-alcoholic Fatty Liver Disease/physiopathology ; Obesity/metabolism
Czasopismo naukowe
Tytuł :
Effects of anticancer drugs on the cardiac mitochondrial toxicity and their underlying mechanisms for novel cardiac protective strategies.
Autorzy :
Kim CW; Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea.
Choi KC; Laboratory of Biochemistry and Immunology, College of Veterinary Medicine, Chungbuk National University, Cheongju, Chungbuk, Republic of Korea. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Jul 15; Vol. 277, pp. 119607. Date of Electronic Publication: 2021 May 13.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Antineoplastic Agents/*adverse effects
Mitochondria, Heart/*metabolism
Myocytes, Cardiac/*metabolism
Animals ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Arsenic Trioxide/pharmacology ; Cardiotoxicity/metabolism ; Cardiovascular System/drug effects ; Doxorubicin/pharmacology ; Endoplasmic Reticulum Stress/drug effects ; Heart Diseases/metabolism ; Humans ; Mitochondria/drug effects ; Mitochondria/metabolism ; Mitochondria, Heart/drug effects ; Myocytes, Cardiac/drug effects ; Oxidative Stress/drug effects ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Skeletal Muscle Mitochondria Dysfunction in Genetic Neuromuscular Disorders with Cardiac Phenotype.
Autorzy :
Ignatieva E; Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Smolina N; Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Kostareva A; Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.; Department of Woman and Child Health, Karolinska Institute, 17177 Stockholm, Sweden.
Dmitrieva R; Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Jul 08; Vol. 22 (14). Date of Electronic Publication: 2021 Jul 08.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Cardiomyopathies/*genetics
Heart/*physiopathology
Mitochondria, Muscle/*metabolism
Muscle, Skeletal/*metabolism
Neuromuscular Diseases/*genetics
Animals ; Cardiomyopathies/metabolism ; Cardiomyopathies/pathology ; Disease Models, Animal ; Energy Metabolism ; Humans ; Mice ; Mitochondria, Heart/metabolism ; Muscle Proteins/deficiency ; Muscle Proteins/genetics ; Muscle Proteins/physiology ; Muscle, Skeletal/ultrastructure ; Muscular Atrophy/metabolism ; Muscular Dystrophies/genetics ; Muscular Dystrophies/metabolism ; Muscular Dystrophies/pathology ; Muscular Dystrophy, Animal/genetics ; Muscular Dystrophy, Animal/metabolism ; Muscular Dystrophy, Animal/pathology ; Neuromuscular Diseases/metabolism ; Neuromuscular Diseases/pathology ; Phenotype
Czasopismo naukowe
Tytuł :
Low abundance of Mfn2 protein correlates with reduced mitochondria-SR juxtaposition and mitochondrial cristae density in human men skeletal muscle: Examining organelle measurements from TEM images.
Autorzy :
Castro-Sepulveda M; Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.; Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Fernández-Verdejo R; Carrera de Nutrición y Dietética, Departamento de Ciencias de la Salud, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile.
Tuñón-Suárez M; Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Morales-Zúñiga J; Laboratorio de Ciencias del Deporte, Clínica Sports Medicina Deportiva, Viña del Mar, Chile.
Troncoso M; Faculty of Chemical and Pharmaceutical Science & Faculty of Medicine, Advanced Center for Chronic Diseases (ACCDiS), Universidad de Chile, Santiago, Chile.
Jannas-Vela S; Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.
Zbinden-Foncea H; Escuela de Kinesiología, Facultad de Medicina, Universidad Finis Terrae, Santiago, Chile.; Centro de Salud Deportiva, Clinica Santa Maria, Santiago, Chile.
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Źródło :
FASEB journal : official publication of the Federation of American Societies for Experimental Biology [FASEB J] 2021 Apr; Vol. 35 (4), pp. e21553.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
GTP Phosphohydrolases/*metabolism
Mitochondria/*metabolism
Mitochondrial Membranes/*metabolism
Mitochondrial Proteins/*metabolism
Muscle, Skeletal/*metabolism
Calcium/metabolism ; Humans ; Mitochondria/ultrastructure ; Mitochondria, Muscle/metabolism ; Mitochondrial Membranes/ultrastructure ; Muscle, Skeletal/ultrastructure ; Sarcoplasmic Reticulum/metabolism
Czasopismo naukowe
Tytuł :
An integrative approach to the regulation of mitochondrial respiration during exercise: Focus on high-intensity exercise.
Autorzy :
Calbet JAL; Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Spain; Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Paseo Blas Cabrera Felipe 'Físico' (s/n), 35017, Las Palmas de Gran Canaria, Canary Islands, Spain; Department of Physical Performance, The Norwegian School of Sport Sciences, Postboks, 4014 Ulleval Stadion, 0806 Oslo, Norway. Electronic address: .
Martín-Rodríguez S; Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Spain; Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Paseo Blas Cabrera Felipe 'Físico' (s/n), 35017, Las Palmas de Gran Canaria, Canary Islands, Spain.
Martin-Rincon M; Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Spain; Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Paseo Blas Cabrera Felipe 'Físico' (s/n), 35017, Las Palmas de Gran Canaria, Canary Islands, Spain.
Morales-Alamo D; Department of Physical Education, University of Las Palmas de Gran Canaria, Campus Universitario de Tafira s/n, 35017, Las Palmas de Gran Canaria, Spain; Research Institute of Biomedical and Health Sciences (IUIBS), University of Las Palmas de Gran Canaria, Paseo Blas Cabrera Felipe 'Físico' (s/n), 35017, Las Palmas de Gran Canaria, Canary Islands, Spain.
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Źródło :
Redox biology [Redox Biol] 2020 Aug; Vol. 35, pp. 101478. Date of Electronic Publication: 2020 Feb 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Exercise*
Mitochondria, Muscle*/metabolism
Female ; Humans ; Male ; Mitochondria/metabolism ; Muscle, Skeletal/metabolism ; Oxygen Consumption ; Respiration
Czasopismo naukowe
Tytuł :
Disturbed mitochondrial redox state and tissue energy charge in cholestasis.
Autorzy :
Ghanbarinejad V; Toxicology Laboratory, Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Ommati MM; Department of Bioinformatics, College of Life Sciences, Shanxi Agricultural University, Taigu, Shanxi, China.
Jia Z; Department of Veterinary Medicine, College of Animal Sciences and Veterinary Medicine, Shanxi Agricultural University, Taigu, Shanxi, China.
Farshad O; Toxicology Laboratory, Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Jamshidzadeh A; Toxicology Laboratory, Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.; Department of Pharmacology and Toxicology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Heidari R; Toxicology Laboratory, Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
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Źródło :
Journal of biochemical and molecular toxicology [J Biochem Mol Toxicol] 2021 Sep; Vol. 35 (9), pp. e22846. Date of Electronic Publication: 2021 Jul 12.
Typ publikacji :
Journal Article
MeSH Terms :
Energy Metabolism*
Cholestasis/*metabolism
Mitochondria, Liver/*metabolism
Mitochondria, Muscle/*metabolism
Animals ; Cholestasis/pathology ; Disease Models, Animal ; Male ; Mitochondria, Liver/pathology ; Mitochondria, Muscle/pathology ; Organ Specificity ; Oxidation-Reduction ; Rats ; Rats, Sprague-Dawley
Czasopismo naukowe
Tytuł :
At the heart of mitochondrial quality control: many roads to the top.
Autorzy :
Gottlieb RA; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA. .
Piplani H; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
Sin J; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
Sawaged S; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
Hamid SM; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
Taylor DJ; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
de Freitas Germano J; Smidt Heart Institute, Cedars-Sinai Medical Center, AHSP9313, 127 S. San Vicente Blvd., Los Angeles, CA, 90048, USA.
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Źródło :
Cellular and molecular life sciences : CMLS [Cell Mol Life Sci] 2021 Apr; Vol. 78 (8), pp. 3791-3801. Date of Electronic Publication: 2021 Feb 05.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mitochondrial Dynamics*
Mitophagy*
Mitochondria/*metabolism
Animals ; DNA, Mitochondrial/metabolism ; Humans ; Mitochondria, Heart/metabolism ; Mitochondrial Proteins/metabolism ; Unfolded Protein Response
Czasopismo naukowe
Tytuł :
Multiplexed quantitative evaluation on mitochondrial toxicity of tris (2,3-dibromopropyl) phosphate in hepatocyte.
Autorzy :
Ma X; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China.
Lu D; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China.
Liu Y; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China.
Le Y; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China.
Chen H; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China.
Li X; Cangzhou Medical College, Cangzhou 061001, Hebei, People's Republic of China. Electronic address: .
Wang C; Academy of Chinese Medical Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China; School of Life Science, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang, People's Republic of China. Electronic address: .
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Źródło :
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2021 Sep 15; Vol. 221, pp. 112425. Date of Electronic Publication: 2021 Jun 16.
Typ publikacji :
Journal Article
MeSH Terms :
Flame Retardants/*toxicity
Hepatocytes/*drug effects
Mitochondria/*drug effects
Organophosphates/*toxicity
Animals ; Cell Line ; Hepatocytes/physiology ; Lipid Metabolism/drug effects ; Membrane Potential, Mitochondrial/drug effects ; Mice ; Mitochondria/physiology ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł :
Neurological Implications of COVID-19: Role of Redox Imbalance and Mitochondrial Dysfunction.
Autorzy :
Kaundal RK; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Raebareli, Lucknow, India.; Icahn School of Medicine At Mount Sinai, 1470 Madison Ave, New York, NY, USA.
Kalvala AK; College of Pharmacy and Pharmaceutical Sciences, Florida A&M University, Tallahassee, FL, North America, USA.
Kumar A; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER)-Kolkata, Kolkata, India. .
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Źródło :
Molecular neurobiology [Mol Neurobiol] 2021 Sep; Vol. 58 (9), pp. 4575-4587. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article; Review
MeSH Terms :
COVID-19/*complications
Mitochondria/*physiology
SARS-CoV-2/*pathogenicity
Animals ; Antiviral Agents/pharmacology ; Antiviral Agents/therapeutic use ; COVID-19/metabolism ; Central Nervous System/virology ; Drug Repositioning ; Endothelium, Vascular/physiopathology ; Endothelium, Vascular/virology ; Humans ; Mice ; Mitochondria/drug effects ; Mitochondria/pathology ; Models, Biological ; Olfactory Nerve/virology ; Organ Specificity ; Oxidation-Reduction ; Oxidative Stress/drug effects ; Pandemics ; SARS-CoV-2/physiology ; Viral Proteins/physiology ; Viral Tropism ; Viremia/complications ; Virulence ; Virus Internalization
Czasopismo naukowe
Tytuł :
Loss of the mitochondrial phosphate carrier SLC25A3 induces remodeling of the cardiac mitochondrial protein acylome.
Autorzy :
Peoples JN; Division of Pediatric Cardiology, Department of Pediatrics, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, Georgia.
Ghazal N; Division of Pediatric Cardiology, Department of Pediatrics, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, Georgia.
Duong DM; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia.
Hardin KR; Graduate Program in Biochemistry, Cell and Developmental Biology, Graduate Division of Biological and Biomedical Sciences, Emory University, Atlanta, Georgia.
Manning JR; Division of Cardiology, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.
Seyfried NT; Department of Biochemistry, Emory University School of Medicine, Atlanta, Georgia.
Faundez V; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia.
Kwong JQ; Division of Pediatric Cardiology, Department of Pediatrics, Emory University School of Medicine, and Children's Healthcare of Atlanta, Atlanta, Georgia.; Department of Cell Biology, Emory University School of Medicine, Atlanta, Georgia.
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Źródło :
American journal of physiology. Cell physiology [Am J Physiol Cell Physiol] 2021 Sep 01; Vol. 321 (3), pp. C519-C534. Date of Electronic Publication: 2021 Jul 28.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Protein Processing, Post-Translational*
Cardiomyopathies/*genetics
Cation Transport Proteins/*genetics
Isocitrate Dehydrogenase/*genetics
Mitochondria, Heart/*metabolism
Mitochondrial Proteins/*genetics
Myocytes, Cardiac/*metabolism
Phosphate Transport Proteins/*genetics
Solute Carrier Proteins/*genetics
Acetylation ; Animals ; Biological Transport ; Cardiomyopathies/metabolism ; Cardiomyopathies/pathology ; Cation Transport Proteins/deficiency ; Energy Metabolism ; Female ; Gene Regulatory Networks ; Isocitrate Dehydrogenase/metabolism ; Male ; Malonates/metabolism ; Mice ; Mice, Knockout ; Mitochondria, Heart/genetics ; Mitochondria, Heart/pathology ; Mitochondrial Proteins/deficiency ; Models, Molecular ; Myocardium/metabolism ; Myocardium/pathology ; Myocytes, Cardiac/pathology ; Phosphate Transport Proteins/deficiency ; Phosphates ; Protein Conformation ; Protein Interaction Mapping ; Signal Transduction ; Sirtuins/genetics ; Sirtuins/metabolism ; Solute Carrier Proteins/deficiency
Czasopismo naukowe
Tytuł :
Silent information regulator 1 suppresses epithelial-to-mesenchymal transition in lung cancer cells via its regulation of mitochondria status.
Autorzy :
Zhang J; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Peng J; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Kong D; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Wang X; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Wang Z; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Liu J; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Yu W; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Wu H; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Long Z; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Zhang W; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China.
Liu R; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China. Electronic address: .
Hai C; Department of Toxicology, The Ministry of Education Key Lab of Hazard Assessment and Control in Special Operational Environment, Shaanxi Key Lab of Free Radical Biology and Medicine, School of Public Health, Fourth Military Medical University, Xi'an 710032, China. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Sep 01; Vol. 280, pp. 119716. Date of Electronic Publication: 2021 Jun 10.
Typ publikacji :
Journal Article
MeSH Terms :
Epithelial-Mesenchymal Transition*
Lung Neoplasms/*pathology
Mitochondria/*pathology
Sirtuin 1/*metabolism
A549 Cells ; Animals ; Gene Expression Regulation, Neoplastic ; Humans ; Lung Neoplasms/genetics ; Lung Neoplasms/metabolism ; Male ; Mice, Nude ; Mitochondria/genetics ; Mitochondria/metabolism ; Organelle Biogenesis ; Signal Transduction ; Sirtuin 1/genetics ; Transforming Growth Factor beta1/metabolism
Czasopismo naukowe
Tytuł :
Mitochondria: The metabolic switch of cellular oncogenic transformation.
Autorzy :
Tan YQ; Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, Guangdong, PR China; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, PR China.
Zhang X; Shenzhen Bay Laboratory, Shenzhen 518055, Guangdong, PR China.
Zhang S; Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, Guangdong, PR China.
Zhu T; Hefei National Laboratory for Physical Sciences at Microscale and School of Life Sciences, University of Science and Technology of China, Hefei 230000, Anhui, PR China; The CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Life Sciences, University of Science and Technology of China, Hefei 230000, Anhui, PR China.
Garg M; Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR), Amity University, Sector-125, Noida 201313, India.
Lobie PE; Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, Guangdong, PR China; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, PR China; Shenzhen Bay Laboratory, Shenzhen 518055, Guangdong, PR China. Electronic address: .
Pandey V; Tsinghua Berkeley Shenzhen Institute, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, Guangdong, PR China; Institute of Biopharmaceutical and Health Engineering, Tsinghua Shenzhen International Graduate School, Tsinghua University, Shenzhen 518055, PR China. Electronic address: .
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Źródło :
Biochimica et biophysica acta. Reviews on cancer [Biochim Biophys Acta Rev Cancer] 2021 Aug; Vol. 1876 (1), pp. 188534. Date of Electronic Publication: 2021 Mar 29.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Energy Metabolism*/drug effects
Oncogenes*
Cell Transformation, Neoplastic/*metabolism
Mitochondria/*metabolism
Neoplasms/*metabolism
Animals ; Antineoplastic Agents/pharmacology ; Cell Transformation, Neoplastic/genetics ; Cell Transformation, Neoplastic/pathology ; Gene Expression Regulation, Neoplastic ; Genes, Tumor Suppressor ; Humans ; Mitochondria/drug effects ; Mitochondria/genetics ; Mitochondria/pathology ; Neoplasms/drug therapy ; Neoplasms/genetics ; Neoplasms/pathology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Isolation and Quality Control of Functional Mitochondria.
Autorzy :
Hartwig S; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Duesseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Kotzka J; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Duesseldorf, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Lehr S; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center at the Heinrich-Heine-University Duesseldorf, Leibniz Center for Diabetes Research, Duesseldorf, Germany. .; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2276, pp. 41-55.
Typ publikacji :
Journal Article
MeSH Terms :
Cell Fractionation/*methods
Centrifugation, Density Gradient/*methods
Centrifugation, Isopycnic/*methods
Microscopy, Electron/*methods
Mitochondria/*chemistry
Mitochondria/*metabolism
Animals ; Humans ; Liver/ultrastructure ; Mice ; Mitochondria/ultrastructure ; Mitochondria, Liver/chemistry ; Quality Control
Czasopismo naukowe
Tytuł :
Simultaneous Quantification of Mitochondrial ATP and ROS Production Using ATP Energy Clamp Methodology.
Autorzy :
Yu L; Division of Endocrinology and Metabolism, Department of Internal Medicine, The University of Iowa, Iowa City, IA, USA.
Fink BD; Division of Endocrinology and Metabolism, Department of Internal Medicine, The University of Iowa, Iowa City, IA, USA.
Sivitz WI; Division of Endocrinology and Metabolism, Department of Internal Medicine, The University of Iowa, Iowa City, IA, USA. .
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Źródło :
Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2021; Vol. 2276, pp. 271-283.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Adenosine Triphosphate/*metabolism
Hydrogen Peroxide/*metabolism
Magnetic Resonance Spectroscopy/*methods
Mitochondria/*metabolism
Reactive Oxygen Species/*metabolism
Animals ; Deoxyglucose/metabolism ; Energy Metabolism ; Hexokinase/metabolism ; Membrane Potential, Mitochondrial ; Mice ; Mitochondria, Heart/metabolism ; Mitochondria, Liver/metabolism ; Mitochondrial Proton-Translocating ATPases/metabolism
Czasopismo naukowe
Tytuł :
Seasonal changes of mitochondrial autophagy and oxidative response in the testis of the wild ground squirrels ( Spermophilus dauricus ).
Autorzy :
Wang Y; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
Su R; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
Liu P; State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, People's Republic of China.; University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Yuan Z; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
Han Y; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
Zhang H; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
Weng Q; College of Biological Science and Technology, Beijing Forestry University, Beijing, People's Republic of China.
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Źródło :
American journal of physiology. Regulatory, integrative and comparative physiology [Am J Physiol Regul Integr Comp Physiol] 2021 Oct 01; Vol. 321 (4), pp. R625-R633. Date of Electronic Publication: 2021 Sep 08.
Typ publikacji :
Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Breeding*
Energy Metabolism*
Mitophagy*
Oxidative Stress*
Seasons*
Mitochondria/*metabolism
Sciuridae/*metabolism
Testis/*metabolism
Animals ; Catalase/genetics ; Catalase/metabolism ; Male ; Mitochondria/genetics ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism ; Organ Size ; Sciuridae/genetics ; Spermatogenesis ; Superoxide Dismutase/genetics ; Superoxide Dismutase/metabolism ; Transcriptome ; Ubiquitin-Protein Ligases/genetics ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
CCCP-induced mitochondrial dysfunction - characterization and analysis of integrated stress response to cellular signaling and homeostasis.
Autorzy :
Koncha RR; Department of Biochemistry, School of Life Sciences, University of Hyderabad, India.
Ramachandran G; Department of Biochemistry, School of Life Sciences, University of Hyderabad, India.
Sepuri NBV; Department of Biochemistry, School of Life Sciences, University of Hyderabad, India.
Ramaiah KVA; Department of Biochemistry, School of Life Sciences, University of Hyderabad, India.
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Źródło :
The FEBS journal [FEBS J] 2021 Oct; Vol. 288 (19), pp. 5737-5754. Date of Electronic Publication: 2021 Apr 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Activating Transcription Factor 4/*genetics
Adaptor Proteins, Signal Transducing/*genetics
Cell Cycle Proteins/*genetics
Eukaryotic Initiation Factor-2/*genetics
Mitochondria/*genetics
Protein Kinases/*genetics
Acetamides/pharmacology ; Autophagy/genetics ; Carbonyl Cyanide m-Chlorophenyl Hydrazone/pharmacology ; Cyclohexylamines/pharmacology ; Gene Expression Regulation/drug effects ; Hep G2 Cells ; Humans ; Mitochondria/metabolism ; Mitochondria/pathology ; Oxidative Phosphorylation/drug effects ; Oxidative Stress/drug effects ; Phosphorylation/drug effects ; Stress, Physiological/drug effects ; Transcription Factor CHOP/genetics
Czasopismo naukowe

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