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Wyszukujesz frazę ""Mitochondrial Dynamics"" wg kryterium: Temat


Tytuł:
Regulation of mitochondrial fusion and mitophagy by intra-tumoral delivery of membrane-fused mitochondria or Midiv-1 enhances sensitivity to doxorubicin in triple-negative breast cancer.
Autorzy:
Chang JC; Center of Regenerative Medicine and Tissue Repair, Institute of ATP, Changhua Christian Hospital, Changhua 50094, Taiwan. Electronic address: .
Chang HS; Center of Regenerative Medicine and Tissue Repair, Institute of ATP, Changhua Christian Hospital, Changhua 50094, Taiwan.
Yeh CY; Center of Regenerative Medicine and Tissue Repair, Institute of ATP, Changhua Christian Hospital, Changhua 50094, Taiwan.
Chang HJ; Center of Regenerative Medicine and Tissue Repair, Institute of ATP, Changhua Christian Hospital, Changhua 50094, Taiwan.
Cheng WL; Department of Vascular and Genomic Center, Changhua Christian Hospital, Changhua 50094, Taiwan.
Lin TT; Department of Vascular and Genomic Center, Changhua Christian Hospital, Changhua 50094, Taiwan.
Liu CS; Department of Vascular and Genomic Center, Changhua Christian Hospital, Changhua 50094, Taiwan; Department of Neurology, Changhua Christian Hospital, Changhua 50094, Taiwan; School of Chinese Medicine, Graduate Institute of Chinese Medicine, Graduate Institute of Integrated Medicine, College of Chinese Medicine, Research Center for Chinese Medicine and Acupuncture, China Medical University, Taichung 40447, Taiwan; Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung 40227, Taiwan.
Chen ST; Comprehensive Breast Cancer Center, Changhua Christian Hospital, Changhua 50094, Taiwan; Department of Medical Research, Changhua Christian Hospital, Changhua 50094, Taiwan. Electronic address: .
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Źródło:
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2022 Sep; Vol. 153, pp. 113484. Date of Electronic Publication: 2022 Aug 02.
Typ publikacji:
Journal Article
MeSH Terms:
Doxorubicin*/metabolism
Doxorubicin*/pharmacology
Mitochondrial Dynamics*/drug effects
Mitochondrial Dynamics*/physiology
Mitophagy*/drug effects
Mitophagy*/physiology
Triple Negative Breast Neoplasms*/drug therapy
Triple Negative Breast Neoplasms*/pathology
Animals ; Humans ; Mice ; Mitochondria/metabolism ; Mitochondria/physiology ; Phosphatidylinositol 3-Kinases/metabolism
Czasopismo naukowe
Tytuł:
Tamoxifen modulates mitochondrial dynamics through AMPK and MAPK during nutrition deprivation.
Autorzy:
Vijayakumar G; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Guwahati, Assam, India.
Swetha US; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Guwahati, Assam, India.
Sudhagar S; Department of Biotechnology, National Institute of Pharmaceutical Education and Research, Guwahati, Assam, India.
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Źródło:
Cell biology international [Cell Biol Int] 2022 Oct; Vol. 46 (10), pp. 1661-1671. Date of Electronic Publication: 2022 Jul 12.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*/physiology
Tamoxifen*/pharmacology
AMP-Activated Protein Kinases/metabolism ; Humans ; Phosphorylation ; Signal Transduction
Czasopismo naukowe
Tytuł:
Blocking exosomal secretion aggravates 1,4-benzoquinone-induced mitochondrial fission activated by the AMPK/MFF/Drp1 pathway in HL-60 cells.
Autorzy:
Lu F; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.
Zhang Q; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.; Department of Pharmacology, School of Pharmacy, Qilu Medical University, Shandong, China.
Zhang M; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.
Sun S; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.
Yang X; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.
Yan H; Department of Preventive Medicine, School of Public Health and Management, Wenzhou Medical University, Zhejiang, China.
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Źródło:
Journal of applied toxicology : JAT [J Appl Toxicol] 2022 Oct; Vol. 42 (10), pp. 1618-1627. Date of Electronic Publication: 2022 May 22.
Typ publikacji:
Journal Article
MeSH Terms:
AMP-Activated Protein Kinases*
Mitochondrial Dynamics*
Benzene ; Benzoquinones/toxicity ; DNA, Mitochondrial ; Dynamins/metabolism ; HL-60 Cells ; Humans ; Membrane Proteins/metabolism ; Mitochondrial Proteins/genetics ; Mitochondrial Proteins/metabolism
Czasopismo naukowe
Tytuł:
Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy.
Autorzy:
Hong X; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.
Isern J; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.
Campanario S; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Perdiguero E; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Ramírez-Pardo I; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Segalés J; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Hernansanz-Agustín P; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.
Curtabbi A; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.
Deryagin O; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Pollán A; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain.
González-Reyes JA; Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, 14014 Córdoba, Spain.
Villalba JM; Departamento de Biología Celular, Fisiología e Inmunología, Universidad de Córdoba, 14014 Córdoba, Spain.
Sandri M; Venetian Institute of Molecular Medicine, 35129 Padova, Italy; Department of Biomedical Sciences, University of Padova, 35100 Padova, Italy.
Serrano AL; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain.
Enríquez JA; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain; CIBERFES, Madrid, Spain. Electronic address: .
Muñoz-Cánoves P; Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain; Department of Experimental and Health Sciences, Pompeu Fabra University (UPF), CIBERNED, 08003 Barcelona, Spain; ICREA, 08003 Barcelona, Spain; Altos Labs, San Diego, CA, USA. Electronic address: .
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Źródło:
Cell stem cell [Cell Stem Cell] 2022 Sep 01; Vol. 29 (9), pp. 1298-1314.e10. Date of Electronic Publication: 2022 Aug 22.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*
Mitophagy*
Aged ; Humans ; Mitochondria/metabolism ; Muscle, Skeletal/metabolism ; Muscles/metabolism ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Cadmium exposure causes mitochondrial fission and fusion disorder in the pig hypothalamus via the PI3K/AKT pathway.
Autorzy:
Chen D; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China.
Yao Y; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China.
Shi X; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China.
Li X; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China.
Cui W; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China.
Xu S; College of Veterinary Medicine, Northeast Agricultural University, Harbin 150000, PR China. Electronic address: .
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Źródło:
Ecotoxicology and environmental safety [Ecotoxicol Environ Saf] 2022 Sep 01; Vol. 242, pp. 113880. Date of Electronic Publication: 2022 Jul 21.
Typ publikacji:
Journal Article
MeSH Terms:
Cadmium*/toxicity
Mitochondrial Dynamics*
Animals ; Apoptosis ; Hypothalamus/metabolism ; Necrosis ; Phosphatidylinositol 3-Kinases/genetics ; Phosphatidylinositol 3-Kinases/metabolism ; Proto-Oncogene Proteins c-akt/genetics ; Proto-Oncogene Proteins c-akt/metabolism ; Swine
Czasopismo naukowe
Tytuł:
SUMOylation of SYNJ2BP-COX16 promotes breast cancer progression through DRP1-mediated mitochondrial fission.
Autorzy:
Wang M; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Wei R; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Li G; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China; College of New Materials and Chemical Engineering, Beijing Key Laboratory of Enze Biomass Fine Chemicals, Beijing Institute of Petrochemical Technology, Beijing, China. Electronic address: .
Bi HL; Institute of Cardiovascular Diseases, First Affiliated Hospital of Dalian Medical University, Dalian, Liaoning Province, 116024, China. Electronic address: diana_.
Jia Z; College of New Materials and Chemical Engineering, Beijing Key Laboratory of Enze Biomass Fine Chemicals, Beijing Institute of Petrochemical Technology, Beijing, China. Electronic address: .
Zhang M; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Pang M; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Li X; School of Environmental Science and Technology, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Ma L; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
Tang Y; School of Bioengineering, Dalian University of Technology, No.2 Linggong Road, Dalian, Liaoning Province, 116024, China. Electronic address: .
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Źródło:
Cancer letters [Cancer Lett] 2022 Oct 28; Vol. 547, pp. 215871. Date of Electronic Publication: 2022 Aug 20.
Typ publikacji:
Journal Article
MeSH Terms:
Breast Neoplasms*/genetics
Mitochondrial Dynamics*/genetics
Dynamins/genetics ; Dynamins/metabolism ; Electron Transport Complex IV/genetics ; Female ; GTP Phosphohydrolases/genetics ; GTP Phosphohydrolases/metabolism ; Humans ; Membrane Proteins/metabolism ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Mitochondrial Proteins/metabolism ; Sumoylation
Czasopismo naukowe
Tytuł:
OPA1 regulation of mitochondrial dynamics in skeletal and cardiac muscle.
Autorzy:
Noone J; 3U Diabetes Partnership, School of Health and Human Performance, Dublin City University, Dublin, Ireland; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland; School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute (TBSI), Trinity College Dublin, Dublin, Ireland; Translational Research Institute, AdventHealth, Orlando, FL, USA.
O'Gorman DJ; 3U Diabetes Partnership, School of Health and Human Performance, Dublin City University, Dublin, Ireland; National Institute for Cellular Biotechnology, Dublin City University, Dublin, Ireland; SSPC, The SFI Research Centre for Pharmaceuticals, Bernal Institute, University of Limerick, Limerick, Ireland. Electronic address: .
Kenny HC; Division of Endocrinology and Metabolism, Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA, USA; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
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Źródło:
Trends in endocrinology and metabolism: TEM [Trends Endocrinol Metab] 2022 Oct; Vol. 33 (10), pp. 710-721. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Review
MeSH Terms:
GTP Phosphohydrolases*/genetics
GTP Phosphohydrolases*/metabolism
Mitochondrial Dynamics*
Muscle, Skeletal*/metabolism
Myocardium*/metabolism
Humans ; Mitochondria/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondrial Proteins/metabolism
Czasopismo naukowe
Tytuł:
The mitochondrial fission protein Drp1 in liver is required to mitigate NASH and prevents the activation of the mitochondrial ISR.
Autorzy:
Steffen J; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Ngo J; Department of Chemistry and Biochemistry, UCLA. 607 Charles E. Young Dr., Los Angeles, CA 90095, USA; Department of Medicine, Division of Endocrinology, David Geffen School of Medicine at UCLA. 650 Charles E. Young Dr., Los Angeles, CA 90095, USA.
Wang SP; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Williams K; Department of Chemistry and Biochemistry, UCLA. 607 Charles E. Young Dr., Los Angeles, CA 90095, USA.
Kramer HF; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Ho G; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Rodriguez C; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Yekkala K; Preclinical Safety and Translational Sciences, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Amuzie C; Preclinical Safety and Translational Sciences, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Bialecki R; Preclinical Safety and Translational Sciences, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Norquay L; Business Development, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Nawrocki AR; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Erion M; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA.
Pocai A; Cardiovascular and Metabolic Disease Research, Janssen Research & Development, LLC, 1400 McKean Road, Spring House, PA 19477-0776, USA. Electronic address: .
Shirihai OS; Department of Medicine, Division of Endocrinology, David Geffen School of Medicine at UCLA. 650 Charles E. Young Dr., Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA. 650 Charles E. Young Dr., Los Angeles, CA 90095, USA. Electronic address: .
Liesa M; Department of Medicine, Division of Endocrinology, David Geffen School of Medicine at UCLA. 650 Charles E. Young Dr., Los Angeles, CA 90095, USA; Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at UCLA. 650 Charles E. Young Dr., Los Angeles, CA 90095, USA; Molecular Biology Institute at UCLA, 611 Charles E. Young Drive East, Los Angeles, CA 90095-1570, USA; Institut de Biologia Molecular de Barcelona, IBMB, CSIC, Baldiri Reixac 4-8, Barcelona, Catalonia, 08028, Spain. Electronic address: .
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Źródło:
Molecular metabolism [Mol Metab] 2022 Oct; Vol. 64, pp. 101566. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural
MeSH Terms:
Liver*/metabolism
Mitochondrial Dynamics*
Animals ; Diet, High-Fat/adverse effects ; Fibrosis ; Inflammation/metabolism ; Mice ; Mice, Inbred C57BL ; Mitochondria/genetics ; RNA, Small Interfering/metabolism ; Weight Loss
Czasopismo naukowe
Tytuł:
Flow pattern-dependent mitochondrial dynamics regulates the metabolic profile and inflammatory state of endothelial cells.
Autorzy:
Hong SG; Cardiovascular Research Center, Lewis Katz School of Medicine, and.; Department of Kinesiology, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA.
Shin J; Cardiovascular Research Center, Lewis Katz School of Medicine, and.
Choi SY; Cardiovascular Research Center, Lewis Katz School of Medicine, and.
Powers JC; Cardiovascular Research Center, Lewis Katz School of Medicine, and.
Meister BM; Cardiovascular Research Center, Lewis Katz School of Medicine, and.; Department of Kinesiology, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA.
Sayoc J; Cardiovascular Research Center, Lewis Katz School of Medicine, and.
Son JS; Laboratory of Perinatal Kinesioepigenetics, Department of Obstetrics, Gynecology and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Tierney R; Department of Kinesiology, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA.
Recchia FA; Cardiovascular Research Center, Lewis Katz School of Medicine, and.; Institute of Clinical Physiology, National Research Council, Pisa, Italy.; Institute of Life Sciences, Scuola Superiore Sant’Anna, Pisa, Italy
Brown MD; Department of Kinesiology, School of Public Health, University of Maryland, College Park, Maryland, USA.
Yang X; Cardiovascular Research Center, Lewis Katz School of Medicine, and.
Park JY; Cardiovascular Research Center, Lewis Katz School of Medicine, and.; Department of Kinesiology, College of Public Health, Temple University, Philadelphia, Pennsylvania, USA.; Robbins College of Health and Human Sciences, Baylor University, Waco, Texas, USA.
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Źródło:
JCI insight [JCI Insight] 2022 Sep 22; Vol. 7 (18). Date of Electronic Publication: 2022 Sep 22.
Typ publikacji:
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms:
Endothelial Cells*/metabolism
Mitochondrial Dynamics*
Dynamins ; Fatty Acids/metabolism ; Hypoxia-Inducible Factor 1/metabolism ; Metabolome ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Expression of mitochondrial dynamic markers in adenoid cystic carcinoma.
Autorzy:
Sant'Ana MSP; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
de Cáceres CVBL; Department of Oral Diagnosis, Area of Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Lima LA; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Soares CD; Department of Oral Diagnosis, Area of Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Radhakrishnan R; Manipal College of Dental Sciences, Manipal, India.
Gomez RS; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Vargas PA; Department of Oral Diagnosis, Area of Pathology, Piracicaba Dental School, University of Campinas, Piracicaba, Brazil.
Fonseca FP; Department of Oral Surgery and Pathology, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
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Źródło:
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology [J Oral Pathol Med] 2022 Sep; Vol. 51 (8), pp. 702-709. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article
MeSH Terms:
Carcinoma, Adenoid Cystic*/metabolism
Mitochondrial Dynamics*
Humans ; Mitochondria
Czasopismo naukowe
Tytuł:
Fission impossible: Mitochondrial dynamics direct muscle stem cell fates.
Autorzy:
Lee JH; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA.
Mourkioti F; Department of Orthopaedic Surgery, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA; Department of Cell and Developmental Biology, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA; Penn Institute for Regenerative Medicine, Musculoskeletal Regeneration Program, Perelman School of Medicine, The University of Pennsylvania, Philadelphia, PA, USA. Electronic address: .
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Źródło:
Cell stem cell [Cell Stem Cell] 2022 Sep 01; Vol. 29 (9), pp. 1287-1289.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*
Muscle, Skeletal*
Myoblasts/metabolism
Czasopismo naukowe
Tytuł:
Mitohormesis and mitochondrial dynamics in the regulation of stem cell fate.
Autorzy:
Barzegari A; Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
Aaboulhassanzadeh S; Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
Landon R; CNRS UMR7052-INSERM U1271, Laboratory of Osteoarticular Biology, Bioengineering and Bioimaging, Paris Diderot University, Paris, France.
Gueguen V; Université Sorbonne Paris Nord, INSERM U1148, Laboratory for Vascular Translational Science, Cardiovascular Bioengineering, Villetaneuse, France.
Meddahi-Pellé A; Université Sorbonne Paris Nord, INSERM U1148, Laboratory for Vascular Translational Science, Cardiovascular Bioengineering, Villetaneuse, France.
Parvizpour S; Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
Anagnostou F; CNRS UMR7052-INSERM U1271, Laboratory of Osteoarticular Biology, Bioengineering and Bioimaging, Paris Diderot University, Paris, France.
Pavon-Djavid G; Université Sorbonne Paris Nord, INSERM U1148, Laboratory for Vascular Translational Science, Cardiovascular Bioengineering, Villetaneuse, France.
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Źródło:
Journal of cellular physiology [J Cell Physiol] 2022 Sep; Vol. 237 (9), pp. 3435-3448. Date of Electronic Publication: 2022 Jul 01.
Typ publikacji:
Journal Article; Review
MeSH Terms:
Mitochondria*/metabolism
Mitochondrial Dynamics*
Cell Differentiation ; Hormesis ; Stem Cells/metabolism
Czasopismo naukowe
Tytuł:
Nuclear receptor Nur77 protects against oxidative stress by maintaining mitochondrial homeostasis via regulating mitochondrial fission and mitophagy in smooth muscle cell.
Autorzy:
Geng N; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen T; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Chen L; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Zhang H; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Sun L; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Lyu Y; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Che X; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Xiao Q; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Tao Z; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Shao Q; Department of Cardiology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China; Department of Cardiology, Shanghai Chest Hospital, Shanghai Jiao Tong University School of Medicine, 241 West Huaihai Road, Shanghai 200030, China. Electronic address: .
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Źródło:
Journal of molecular and cellular cardiology [J Mol Cell Cardiol] 2022 Sep; Vol. 170, pp. 22-33. Date of Electronic Publication: 2022 Jun 02.
Typ publikacji:
Journal Article
MeSH Terms:
Aortic Aneurysm, Abdominal*/metabolism
Mitochondrial Dynamics*
Nuclear Receptor Subfamily 4, Group A, Member 1*/genetics
Nuclear Receptor Subfamily 4, Group A, Member 1*/metabolism
Oxidative Stress*
Angiotensin II/metabolism ; Animals ; Homeostasis ; Mice ; Mitophagy ; Myocytes, Smooth Muscle/metabolism
Czasopismo naukowe
Tytuł:
MTP18 inhibition triggers mitochondrial hyperfusion to induce apoptosis through ROS-mediated lysosomal membrane permeabilization-dependent pathway in oral cancer.
Autorzy:
Panigrahi DP; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, 769008, Odisha, India.
Patra S; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, 769008, Odisha, India.
Behera BP; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, 769008, Odisha, India.
Behera PK; Post Graduate Department of Chemistry, Berhampur University, Bhanja Bihar, Berhampur, 760007, India.
Patil S; Division of Oral Pathology, Department of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia; Centre of Molecular Medicine and Diagnostics (COMManD), Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India.
Patro BS; Bio-Organic Division, Bhabha Atomic Research Centre, Mumbai, India.
Rout L; Post Graduate Department of Chemistry, Berhampur University, Bhanja Bihar, Berhampur, 760007, India. Electronic address: .
Sarangi I; Department of Biomedical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. Electronic address: .
Bhutia SK; Cancer and Cell Death Laboratory, Department of Life Science, National Institute of Technology Rourkela, Sundargarh, 769008, Odisha, India. Electronic address: .
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Źródło:
Free radical biology & medicine [Free Radic Biol Med] 2022 Sep; Vol. 190, pp. 307-319. Date of Electronic Publication: 2022 Aug 17.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Mitochondrial Dynamics*
Mouth Neoplasms*/drug therapy
Mouth Neoplasms*/genetics
Mouth Neoplasms*/metabolism
Apoptosis/physiology ; Humans ; Lysosomes/metabolism ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Reactive Oxygen Species/metabolism ; Superoxides/metabolism
Czasopismo naukowe
Tytuł:
SIRT6 promotes mitochondrial fission and subsequent cellular invasion in ovarian cancer.
Autorzy:
Bandopadhyay S; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Prasad P; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
Ray U; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Das Ghosh D; Basic and Translational Research, Saroj Gupta Cancer Centre and Research Institute, Kolkata, India.
Roy SS; Cell Biology and Physiology Division, CSIR-Indian Institute of Chemical Biology, Kolkata, India.
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Źródło:
FEBS open bio [FEBS Open Bio] 2022 Sep; Vol. 12 (9), pp. 1657-1676. Date of Electronic Publication: 2022 Jun 24.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*
Ovarian Neoplasms*/pathology
Sirtuins*/metabolism
Female ; Glycolysis ; Humans ; NAD/metabolism ; Neoplasm Invasiveness
Czasopismo naukowe
Tytuł:
The drp-1-mediated mitochondrial fission inhibitor mdivi-1 impacts the function of ion channels and pathways underpinning vascular smooth muscle tone.
Autorzy:
Ahmed A; Dipartimento di Scienze della Vita, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Trezza A; Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Gentile M; Dipartimento di Scienze della Vita, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Paccagnini E; Dipartimento di Scienze della Vita, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Lupetti P; Dipartimento di Scienze della Vita, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Spiga O; Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena, via A. Moro 2, 53100 Siena, Italy.
Bova S; Department of Pharmaceutical and Pharmacological Sciences, University of Padova, Padova, Italy.
Fusi F; Dipartimento di Biotecnologie, Chimica e Farmacia, Università di Siena, via A. Moro 2, 53100 Siena, Italy. Electronic address: .
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Źródło:
Biochemical pharmacology [Biochem Pharmacol] 2022 Sep; Vol. 203, pp. 115205. Date of Electronic Publication: 2022 Aug 06.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*
Muscle, Smooth, Vascular*/metabolism
Death-Associated Protein Kinases/*metabolism
Quinazolinones/*pharmacology
Animals ; Dynamins/metabolism ; Ion Channels ; Phenylephrine/pharmacology ; Rats ; Vasodilator Agents/pharmacology
Czasopismo naukowe
Tytuł:
Epigenetic control of mitochondrial fission enables hepatic stellate cells activation in liver fibrosis via PGC-1α-Drp1 pathway.
Autorzy:
Yang JJ; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China; Department of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China. Electronic address: .
Wang J; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China; School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Yang Y; Department of Surgical Oncology, The Affiliated Suzhou Science & Technology Town Hospital of Nanjing Medical University, Suzhou, China.
Sun F; Department of Clinical Pharmacology, The Second Hospital of Anhui Medical University, Hefei 230601, China; School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Yang Y; Department of Pharmacology, School of Basic Medical Sciences, Anhui Medical University, Hefei 230032, China.
Li J; School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Tao H; Department of Anesthesiology, The Second Hospital of Anhui Medical University, Hefei 230601, China. Electronic address: .
Lu C; First Affiliated Hospital, Anhui University of Science & Technology, Huainan 232001, China. Electronic address: .
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Źródło:
Mitochondrion [Mitochondrion] 2022 Sep; Vol. 66, pp. 38-50. Date of Electronic Publication: 2022 Jul 26.
Typ publikacji:
Journal Article
MeSH Terms:
Hepatic Stellate Cells*/metabolism
Hepatic Stellate Cells*/pathology
Mitochondrial Dynamics*
Animals ; Epigenesis, Genetic ; Fibrosis ; Liver/pathology ; Liver Cirrhosis/chemically induced ; Liver Cirrhosis/metabolism ; Liver Cirrhosis/pathology ; Mice ; Signal Transduction
Czasopismo naukowe
Tytuł:
Hydrogen-rich medium ameliorates lipopolysaccharides-induced mitochondrial fission and dysfunction in human umbilical vein endothelial cells (HUVECs) via up-regulating HO-1 expression.
Autorzy:
Lian N; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Mao X; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Su Y; Department of Critical Care Medicine, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Wang Y; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Wang Y; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Wang Y; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Chen H; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Zhu R; Department of Anesthesiology, Stomatology Hospital of Tianjin Medical University, Tianjin 300070, China.
Yu Y; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China.
Xie K; Department of Anesthesiology, Tianjin Institute of Anesthesiology, General Hospital of Tianjin Medical University, Tianjin 300052, China; Department of Critical Care Medicine, General Hospital of Tianjin Medical University, Tianjin 300052, China. Electronic address: .
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Źródło:
International immunopharmacology [Int Immunopharmacol] 2022 Sep; Vol. 110, pp. 108936. Date of Electronic Publication: 2022 Jun 20.
Typ publikacji:
Journal Article
MeSH Terms:
Mitochondrial Dynamics*
Sepsis*/metabolism
Adenosine Triphosphate/metabolism ; Heme Oxygenase-1/metabolism ; Human Umbilical Vein Endothelial Cells ; Humans ; Hydrogen/pharmacology ; Lipopolysaccharides/pharmacology
Czasopismo naukowe
Tytuł:
Zeb1 sustains hematopoietic stem cell functions by suppressing mitofusin-2-mediated mitochondrial fusion.
Autorzy:
Zhang K; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Zhao H; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Sheng Y; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Chen X; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Xu P; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.; School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, 200030, Shanghai, China.
Wang J; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Ji Z; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
He Y; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.
Gao WQ; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China.; School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, 200030, Shanghai, China.
Zhu HH; State Key Laboratory of Oncogenes and Related Genes, Renji-Med-X Stem Cell Research Center, Shanghai Cancer Institute, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China. .; School of Biomedical Engineering & Med-X Research Institute, Shanghai Jiao Tong University, 200030, Shanghai, China. .; Department of Urology, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, 200127, Shanghai, China. .
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Źródło:
Cell death & disease [Cell Death Dis] 2022 Aug 25; Vol. 13 (8), pp. 735. Date of Electronic Publication: 2022 Aug 25.
Typ publikacji:
Journal Article
MeSH Terms:
Hematopoietic Stem Cells*/metabolism
Mitochondrial Dynamics*
Animals ; Epithelial-Mesenchymal Transition ; Mice ; Mitochondria/metabolism ; Reactive Oxygen Species/metabolism
Czasopismo naukowe
Tytuł:
Mitochondrial hyperfusion via metabolic sensing of regulatory amino acids.
Autorzy:
Abdullah MO; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Zeng RX; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada.
Margerum CL; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada.
Papadopoli D; Lady Davis Institute, Gerald Bronfman Department of Oncology, Department of Biochemistry, Department of Experimental Medicine, McGill University, Montreal, Canada.
Monnin C; Metabolomics Innovation Resource, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Canada.
Punter KB; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada.
Chu C; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada.
Al-Rofaidi M; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Al-Tannak NF; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Kuwait University, Kuwait City, Kuwait.
Berardi D; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Rattray Z; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Rattray NJW; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Abraham SA; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada.
Eskelinen EL; Institute of Biomedicine, University of Turku, Turku, Finland.
Watson DG; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland.
Avizonis D; Metabolomics Innovation Resource, Rosalind and Morris Goodman Cancer Institute, McGill University, Montreal, Canada.
Topisirovic I; Lady Davis Institute, Gerald Bronfman Department of Oncology, Department of Biochemistry, Department of Experimental Medicine, McGill University, Montreal, Canada.
Chan EYW; Strathclyde Institute for Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, Scotland; Department of Biomedical and Medical Sciences, Queen's University, Kingston, Canada. Electronic address: .
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Źródło:
Cell reports [Cell Rep] 2022 Aug 16; Vol. 40 (7), pp. 111198.
Typ publikacji:
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms:
Amino Acids*/metabolism
Mitochondrial Dynamics*
Amines/metabolism ; Mitochondria/metabolism ; Mitochondrial Proteins/metabolism ; Purines/metabolism
Czasopismo naukowe

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