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Wyszukujesz frazę ""Mitosis"" wg kryterium: Temat


Tytuł :
CHIR99021, trough GSK-3β Targeting, Reduces Epithelioid Sarcoma Cell Proliferation by Activating Mitotic Catastrophe and Autophagy.
Autorzy :
Russi S; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Sgambato A; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Bochicchio AM; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Zoppoli P; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Aieta M; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Capobianco AML; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Ruggieri V; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.; UOC Clinical Pathology, Altamura Hospital, 70022 Altamura, Italy.
Zifarone E; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
Falco G; Department of Biology, University of Naples Federico II, 80133 Naples, Italy.; Biogem-Istituto di Biologia e Genetica Molecolare, 83031 Ariano Irpino, Italy.
Laurino S; IRCCS CROB-Referral Cancer Center of Basilicata, 85028 Rionero in Vulture, Italy.
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Źródło :
International journal of molecular sciences [Int J Mol Sci] 2021 Oct 15; Vol. 22 (20). Date of Electronic Publication: 2021 Oct 15.
Typ publikacji :
Journal Article
MeSH Terms :
Autophagy/*drug effects
Mitosis/*drug effects
Pyridines/*pharmacology
Pyrimidines/*pharmacology
Sarcoma/*pathology
Soft Tissue Neoplasms/*pathology
Adult ; Cell Cycle Checkpoints/drug effects ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Glycogen Synthase Kinase 3 beta/antagonists & inhibitors ; Glycogen Synthase Kinase 3 beta/physiology ; Humans ; Mitosis Modulators/pharmacology ; Sarcoma/mortality ; Soft Tissue Neoplasms/mortality ; Survival Analysis
Czasopismo naukowe
Tytuł :
Unjustly forgotten scientist Wacław Mayzel (1847-1916)-co-discoverer of somatic mitosis.
Autorzy :
Janusz L; Medical University of Gdansk, Gdansk, Poland.
Ewa B; Institute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Warsaw, Poland. .
Janusz K; Medical University of Warsaw, Warsaw, Poland.
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Źródło :
Journal of applied genetics [J Appl Genet] 2021 Dec; Vol. 62 (4), pp. 639-642. Date of Electronic Publication: 2021 Jun 17.
Typ publikacji :
Journal Article
MeSH Terms :
Mitosis*
Animals ; Poland
Czasopismo naukowe
Tytuł :
Chromatin bridges, not micronuclei, activate cGAS after drug-induced mitotic errors in human cells.
Autorzy :
Flynn PJ; Department of Systems Biology, Harvard Medical School, Boston, MA 02115; .
Koch PD; Center for Systems Biology, Massachusetts General Hospital, Boston, MA 02114.
Mitchison TJ; Department of Systems Biology, Harvard Medical School, Boston, MA 02115; .
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Źródło :
Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2021 Nov 30; Vol. 118 (48).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromatin/*physiology
Mitosis/*physiology
Nucleotidyltransferases/*metabolism
Cell Line, Tumor ; Chromatin/genetics ; Humans ; Interferon Type I/genetics ; Intracellular Signaling Peptides and Proteins/metabolism ; Membrane Proteins/genetics ; Micronucleus, Germline/genetics ; Micronucleus, Germline/physiology ; Mitosis/drug effects ; Mitosis/genetics ; Neoplasms/metabolism ; Nucleotides, Cyclic/metabolism ; Nucleotidyltransferases/genetics ; Nucleotidyltransferases/physiology ; Signal Transduction
Czasopismo naukowe
Tytuł :
Securinine induces mitotic block in cancer cells by binding to tubulin and inhibiting microtubule assembly: A possible mechanistic basis for its anticancer activity.
Autorzy :
Ashraf SM; School of Biotechnology, National Institute of Technology Calicut, Calicut, Kerala, India.
Mahanty S; School of Biotechnology, National Institute of Technology Calicut, Calicut, Kerala, India.
Rathinasamy K; School of Biotechnology, National Institute of Technology Calicut, Calicut, Kerala, India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Dec 15; Vol. 287, pp. 120105. Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article
MeSH Terms :
Antineoplastic Agents/*metabolism
Azepines/*metabolism
Heterocyclic Compounds, Bridged-Ring/*metabolism
Lactones/*metabolism
Microtubules/*drug effects
Mitosis/*drug effects
Neoplasms/*metabolism
Piperidines/*metabolism
Tubulin/*metabolism
A549 Cells ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/therapeutic use ; Azepines/pharmacology ; Azepines/therapeutic use ; Dose-Response Relationship, Drug ; HEK293 Cells ; HeLa Cells ; Heterocyclic Compounds, Bridged-Ring/pharmacology ; Heterocyclic Compounds, Bridged-Ring/therapeutic use ; Humans ; Lactones/pharmacology ; Lactones/therapeutic use ; MCF-7 Cells ; Microtubules/metabolism ; Mitosis/physiology ; Neoplasms/drug therapy ; Piperidines/pharmacology ; Piperidines/therapeutic use
Czasopismo naukowe
Tytuł :
The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair.
Autorzy :
Kuo WT; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Zuo L; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Anhui Medical University, Hefei, Anhui, China.
Odenwald MA; Department of Pathology, The University of Chicago, Chicago, Illinois.
Madha S; Department of Medical Oncology and Center for Functional Cancer Epigenetics, Dana-Farber Cancer Institute, Boston, Massachusetts.
Singh G; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.
Gurniak CB; Institute of Genetics, University of Bonn, Bonn, Germany.
Abraham C; Department of Internal Medicine, Yale University, New Haven, Connecticut.
Turner JR; Laboratory of Mucosal Barrier Pathobiology, Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts; Department of Pathology, The University of Chicago, Chicago, Illinois. Electronic address: .
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Źródło :
Gastroenterology [Gastroenterology] 2021 Dec; Vol. 161 (6), pp. 1924-1939. Date of Electronic Publication: 2021 Aug 31.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Cell Proliferation*
Mitosis*
Colon/*metabolism
Epithelial Cells/*metabolism
Inflammatory Bowel Diseases/*metabolism
Intestinal Mucosa/*metabolism
Zonula Occludens-1 Protein/*metabolism
Animals ; Cells, Cultured ; Colon/pathology ; Databases, Genetic ; Disease Models, Animal ; Epithelial Cells/pathology ; Humans ; Inflammatory Bowel Diseases/genetics ; Inflammatory Bowel Diseases/pathology ; Intestinal Mucosa/pathology ; Mice, Knockout ; Permeability ; Spindle Apparatus/genetics ; Spindle Apparatus/metabolism ; Spindle Apparatus/pathology ; Wnt Signaling Pathway ; Wound Healing ; Zonula Occludens-1 Protein/genetics
Czasopismo naukowe
Tytuł :
A link between mitotic defects and mitotic catastrophe: detection and cell fate.
Autorzy :
Sazonova EV; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991.
Petrichuk SV; Federal State Autonomous Institution 'National Medical Research Center for Children's Health' of the Ministry of Health of the Russian Federation, Moscow, Russia, 119296.
Kopeina GS; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991. .
Zhivotovsky B; Faculty of Medicine, MV Lomonosov Moscow State University, Moscow, Russia, 119991. .; Division of Toxicology, Institute of Environmental Medicine, Karolinska Institute, Box 210, 17177, Stockholm, Sweden. .
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Źródło :
Biology direct [Biol Direct] 2021 Dec 09; Vol. 16 (1), pp. 25. Date of Electronic Publication: 2021 Dec 09.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Mitosis*
Neoplasms*
Apoptosis ; Cell Line, Tumor ; DNA Damage ; Humans
Czasopismo naukowe
Tytuł :
Phosphorylation-dependent mitotic SUMOylation drives nuclear envelope-chromatin interactions.
Autorzy :
Ptak C; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.
Saik NO; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.
Premashankar A; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.
Lapetina DL; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.
Aitchison JD; Seattle Children's Research Institute, Seattle, WA.
Montpetit B; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.; Department of Viticulture and Enology, University of California Davis, Davis, CA.
Wozniak RW; Department of Cell Biology, University of Alberta, Edmonton, Alberta, Canada.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Nov 17.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Sumoylation*
Chromatin/*metabolism
Nuclear Envelope/*metabolism
Saccharomyces cerevisiae/*metabolism
Amino Acid Motifs ; Green Fluorescent Proteins/metabolism ; Nuclear Pore/metabolism ; Phosphorylation ; Saccharomyces cerevisiae Proteins/chemistry ; Saccharomyces cerevisiae Proteins/metabolism ; Small Ubiquitin-Related Modifier Proteins/metabolism ; Telomere/metabolism
Czasopismo naukowe
Tytuł :
Tubulin isotypes optimize distinct spindle positioning mechanisms during yeast mitosis.
Autorzy :
Nsamba ET; Genetics, Development, and Cell Biology, Iowa State University, Ames, IA.
Bera A; Genetics, Development, and Cell Biology, Iowa State University, Ames, IA.
Costanzo M; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.
Boone C; Donnelly Centre, University of Toronto, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada.; Chemical Genomics Research Group, RIKEN Center for Sustainable Resource Sciences, Saitama, Japan.
Gupta ML; Genetics, Development, and Cell Biology, Iowa State University, Ames, IA.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Nov 05.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Mitosis*
Saccharomyces cerevisiae/*cytology
Saccharomyces cerevisiae/*metabolism
Saccharomyces cerevisiae Proteins/*metabolism
Spindle Apparatus/*metabolism
Dyneins/metabolism ; Epistasis, Genetic ; Gene Expression Regulation, Fungal ; Microtubules/metabolism ; Protein Isoforms/metabolism ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae Proteins/genetics ; Signal Transduction
Czasopismo naukowe
Tytuł :
iASPP contributes to cell cortex rigidity, mitotic cell rounding, and spindle positioning.
Autorzy :
Mangon A; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Salaün D; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Bouali ML; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Kuzmić M; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Quitard S; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Thuault S; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Isnardon D; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Audebert S; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Puech PH; Laboratoire Adhésion et Inflammation, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Aix Marseille Université, Turing Center for Living Systems, Marseille, France.
Verdier-Pinard P; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
Badache A; Centre de Recherche en Cancérologie de Marseille, Institut National de la Santé et de la Recherche Médicale, Institut Paoli-Calmettes, Aix-Marseille Université, Centre National de la Recherche Scientifique, Marseille, France.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Oct 27.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Intracellular Signaling Peptides and Proteins/*metabolism
Repressor Proteins/*metabolism
Spindle Apparatus/*metabolism
Amino Acid Motifs ; HEK293 Cells ; HeLa Cells ; Humans ; Intracellular Signaling Peptides and Proteins/chemistry ; Microtubule-Associated Proteins/metabolism ; Microtubules/metabolism ; Myosin Type I/metabolism ; Phosphoprotein Phosphatases/metabolism ; Protein Binding ; Repressor Proteins/chemistry
Czasopismo naukowe
Tytuł :
Phosphorylation and Pin1 binding to the LIC1 subunit selectively regulate mitotic dynein functions.
Autorzy :
Kumari A; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.; Manipal Academy of Higher Education, Manipal Karnataka, India.
Kumar C; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.
Pergu R; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.; Manipal Academy of Higher Education, Manipal Karnataka, India.
Kumar M; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.; Council of Scientific and Industrial Research, Centre for Cellular and Molecular Biology, Habsiguda, Hyderabad, Telangana, India.; Academy of Scientific and Innovative Research, New Delhi, India.
Mahale SP; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.; Manipal Academy of Higher Education, Manipal Karnataka, India.
Wasnik N; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.
Mylavarapu SVS; Laboratory of Cellular Dynamics, Regional Centre for Biotechnology, NCR Biotech Science Cluster, third Milestone Faridabad-Gurgaon Expressway, Faridabad Haryana, India.; Manipal Academy of Higher Education, Manipal Karnataka, India.
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Źródło :
The Journal of cell biology [J Cell Biol] 2021 Dec 06; Vol. 220 (12). Date of Electronic Publication: 2021 Oct 28.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Cytoplasmic Dyneins/*metabolism
NIMA-Interacting Peptidylprolyl Isomerase/*metabolism
Protein Subunits/*metabolism
Animals ; Cell Line, Tumor ; Centrosome/metabolism ; Dynactin Complex/metabolism ; Evolution, Molecular ; Golgi Apparatus/metabolism ; Humans ; Interphase ; Kinetochores/metabolism ; Metaphase ; Microtubule-Associated Proteins/metabolism ; Mutant Proteins/metabolism ; Nuclear Envelope/metabolism ; Phosphorylation ; Protein Binding ; Rats ; Zebrafish
Czasopismo naukowe
Tytuł :
Protein kinase RNA-activated controls mitotic progression and determines paclitaxel chemosensitivity through B-cell lymphoma 2 in ovarian cancer.
Autorzy :
Yin L; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.
Zeng Y; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Zeng R; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Chen Y; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Wang TL; Department of Pathology and Sydney Kimmel Comprehensive Cancer Center, Johns Hopkins Medical Institutions, Baltimore, MD, 21205, USA.
Rodabaugh KJ; Department of Gynecologic Oncology, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Yu F; Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Natarajan A; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Karpf AR; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA.
Dong J; Eppley Institute for Research in Cancer and Allied Diseases, Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, 68198, USA. .
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Źródło :
Oncogene [Oncogene] 2021 Dec; Vol. 40 (50), pp. 6772-6785. Date of Electronic Publication: 2021 Nov 19.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mitosis*
Biomarkers, Tumor/*metabolism
Gene Expression Regulation, Neoplastic/*drug effects
Ovarian Neoplasms/*drug therapy
Paclitaxel/*pharmacology
Proto-Oncogene Proteins c-bcl-2/*metabolism
eIF-2 Kinase/*metabolism
Animals ; Antineoplastic Agents, Phytogenic/pharmacology ; Apoptosis ; Biomarkers, Tumor/genetics ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Mice ; Mice, Nude ; Ovarian Neoplasms/genetics ; Ovarian Neoplasms/metabolism ; Ovarian Neoplasms/pathology ; Proto-Oncogene Proteins c-bcl-2/genetics ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays ; eIF-2 Kinase/genetics
Czasopismo naukowe
Tytuł :
RNF20 affects porcine adipocyte differentiation via regulation of mitotic clonal expansion.
Autorzy :
Zhao Y; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Pan J; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Cao C; Guangdong Provincial Key Laboratory of Malignant Tumor Epigenetics and Gene Regulation, Guangdong-Hong Kong Joint Laboratory for RNA Medicine, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, China.
Liang X; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Yang S; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Liu L; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Tao C; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Zhao J; State Key Laboratory of Stem Cell and Reproductive Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, China.
Wang Y; State Key Laboratory of Animal Nutrition, Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
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Źródło :
Cell proliferation [Cell Prolif] 2021 Dec; Vol. 54 (12), pp. e13131. Date of Electronic Publication: 2021 Oct 14.
Typ publikacji :
Journal Article
MeSH Terms :
Adipogenesis*
Cell Differentiation*
Mitosis*
Adipocytes/*metabolism
Ubiquitin-Protein Ligases/*metabolism
Animals ; Histones/metabolism ; Swine
Czasopismo naukowe
Tytuł :
A genetically-encoded crosslinker screen identifies SERBP1 as a PKCε substrate influencing translation and cell division.
Autorzy :
Martini S; Protein Phosphorylation Laboratory, The Francis Crick Institute, London, UK.
Davis K; Protein Phosphorylation Laboratory, The Francis Crick Institute, London, UK.
Faraway R; RNA Network Laboratory, The Francis Crick Institute, London, UK.; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Elze L; Department of Human Genetics, Radboud University Medical Center, Nijmegen, The Netherlands.
Lockwood N; Protein Phosphorylation Laboratory, The Francis Crick Institute, London, UK.
Jones A; Cell Cycle Laboratory, The Francis Crick Institute, London, UK.
Xie X; Synthetic and Functional Biomolecules Center, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.
McDonald NQ; Signalling and Structural Biology Laboratory, The Francis Crick Institute, London, UK.
Mann DJ; Department of Life Sciences, Imperial College London, London, SW7 2AZ, UK.
Armstrong A; Department of Chemistry, Imperial College, London, UK.
Ule J; RNA Network Laboratory, The Francis Crick Institute, London, UK.; Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, Queen Square, London, WC1N 3BG, UK.
Parker PJ; Protein Phosphorylation Laboratory, The Francis Crick Institute, London, UK. .; School of Cancer and Pharmaceutical Sciences, King's College London, Guy's Campus, London, UK. .
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Źródło :
Nature communications [Nat Commun] 2021 Nov 26; Vol. 12 (1), pp. 6934. Date of Electronic Publication: 2021 Nov 26.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Chromosome Segregation*
Mitosis*
Protein Biosynthesis*
Protein Kinase C-epsilon/*metabolism
RNA-Binding Proteins/*metabolism
Aurora Kinase B/metabolism ; HEK293 Cells ; HeLa Cells ; Humans
Czasopismo naukowe
Tytuł :
Regulatory mechanism of cyclins and cyclin-dependent kinases in post-mitotic neuronal cell division.
Autorzy :
Gupta R; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Jha A; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Ambasta RK; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India.
Kumar P; Molecular Neuroscience and Functional Genomics Laboratory, Delhi Technological University (Formerly Delhi College of Engineering), India. Electronic address: .
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Źródło :
Life sciences [Life Sci] 2021 Nov 15; Vol. 285, pp. 120006. Date of Electronic Publication: 2021 Oct 02.
Typ publikacji :
Journal Article; Review
MeSH Terms :
Mitosis*
Cyclin-Dependent Kinases/*metabolism
Cyclins/*metabolism
Neurodegenerative Diseases/*metabolism
Neurodegenerative Diseases/*pathology
Neurons/*metabolism
Neurons/*pathology
Acetylation ; Animals ; Histone Deacetylases/metabolism ; Humans ; Ubiquitin-Protein Ligases/metabolism
Czasopismo naukowe
Tytuł :
MTH1 Inhibitor TH1579 Induces Oxidative DNA Damage and Mitotic Arrest in Acute Myeloid Leukemia.
Autorzy :
Sanjiv K; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Calderón-Montaño JM; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Pham TM; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Erkers T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Tsuber V; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Almlöf I; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Höglund A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Heshmati Y; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Seashore-Ludlow B; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Nagesh Danda A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Gad H; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Wiita E; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Göktürk C; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Rasti A; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Friedrich S; Science for Life Laboratory, Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden.
Centio A; The Finsen Laboratory, Rigshospitalet/National University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Biotech Research and Innovation Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Estruch M; The Finsen Laboratory, Rigshospitalet/National University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Biotech Research and Innovation Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
Våtsveen TK; Department for Cancer Immunology, Institute for Cancer Research, Oslo University Hospital, Oslo, Norway.; KG Jebsen Center for B cell malignancies, Faculty of Medicine, University of Oslo, Oslo, Norway.
Struyf N; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Visnes T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Scobie M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Koolmeister T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Henriksson M; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Wallner O; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Sandvall T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Lehmann S; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.; Department of Medical Sciences, Haematology, Uppsala University, Uppsala, Sweden.
Theilgaard-Mönch K; The Finsen Laboratory, Rigshospitalet/National University Hospital, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Biotech Research and Innovation Center, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Novo Nordisk Foundation Center for Stem Cell Biology, DanStem, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Hematology, Rigshospitalet/National Univ. Hospital, University of Copenhagen, Copenhagen, Denmark.
Garnett MJ; Wellcome Sanger Institute, Cambridge, United Kingdom.
Östling P; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Walfridsson J; Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden.
Helleday T; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden.
Warpman Berglund U; Science for Life Laboratory, Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden. .; Oxcia AB, Stockholm, Sweden.
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Źródło :
Cancer research [Cancer Res] 2021 Nov 15; Vol. 81 (22), pp. 5733-5744. Date of Electronic Publication: 2021 Sep 30.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*
Blast Crisis/*drug therapy
DNA Repair Enzymes/*antagonists & inhibitors
Gene Expression Regulation, Leukemic/*drug effects
Leukemia, Myeloid, Acute/*drug therapy
Neoplastic Stem Cells/*drug effects
Phosphoric Monoester Hydrolases/*antagonists & inhibitors
Pyrimidines/*pharmacology
Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis ; Blast Crisis/genetics ; Blast Crisis/metabolism ; Blast Crisis/pathology ; Cell Proliferation ; Cytarabine/administration & dosage ; Doxorubicin/administration & dosage ; Female ; Humans ; Leukemia, Myeloid, Acute/genetics ; Leukemia, Myeloid, Acute/metabolism ; Leukemia, Myeloid, Acute/pathology ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Neoplastic Stem Cells/metabolism ; Neoplastic Stem Cells/pathology ; Prognosis ; Reactive Oxygen Species/metabolism ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
Czasopismo naukowe
Tytuł :
Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration.
Autorzy :
Udagawa T; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.; Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.
Atkinson PJ; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.
Milon B; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Abitbol JM; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.
Song Y; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Sperber M; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Huarcaya Najarro E; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.
Scheibinger M; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.
Elkon R; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Hertzano R; Department of Otorhinolaryngology-Head and Neck Surgery, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.; Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.; Department of Anatomy and Neurobiology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.
Cheng AG; Department of Otolaryngology-Head and Neck Surgery, Stanford University School of Medicine, Stanford, California, United States of America.
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Źródło :
PLoS biology [PLoS Biol] 2021 Nov 10; Vol. 19 (11), pp. e3001445. Date of Electronic Publication: 2021 Nov 10 (Print Publication: 2021).
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
MeSH Terms :
Genetic Association Studies*
Mitosis*
Protein Biosynthesis*
Cell Lineage/*genetics
Cochlea/*cytology
Regeneration/*genetics
Stem Cells/*cytology
Stem Cells/*metabolism
Animals ; Cell Differentiation ; Cell Survival ; Epithelial Cells/cytology ; Gene Expression Regulation ; Integrases/metabolism ; Mice ; Multigene Family ; Receptors, G-Protein-Coupled/metabolism
Czasopismo naukowe
Tytuł :
Structure of mitotic chromosomes.
Autorzy :
Beel AJ; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA.
Azubel M; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: .
Matteï PJ; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA.
Kornberg RD; Department of Structural Biology, Stanford University, Stanford, CA 94305, USA.
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Źródło :
Molecular cell [Mol Cell] 2021 Nov 04; Vol. 81 (21), pp. 4369-4376.e3. Date of Electronic Publication: 2021 Sep 13.
Typ publikacji :
Journal Article; Research Support, N.I.H., Extramural
MeSH Terms :
Mitosis*
Chromosomes/*ultrastructure
DNA/*chemistry
Nucleosomes/*metabolism
Amino Acid Motifs ; Chromatin/chemistry ; Cryoelectron Microscopy ; Green Fluorescent Proteins/metabolism ; HeLa Cells ; Histones/chemistry ; Humans ; Microscopy, Fluorescence ; Nucleosomes/chemistry ; Spermidine/chemistry ; Tomography
Czasopismo naukowe
Tytuł :
Disruption of desmosome function leads to increased centrosome clustering in 14-3-3γ-knockout cells with supernumerary centrosomes.
Autorzy :
Tilwani S; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.; Homi Bhabha National Institute, Training School Complex, Mumbai, India.
Gandhi K; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.
Narayan S; Department of Chemical Sciences, TIFR, Mumbai, India.
Ainavarapu SRK; Department of Chemical Sciences, TIFR, Mumbai, India.
Dalal SN; Cell and Tumor Biology, Advanced Centre for Treatment Research and Education in Cancer (ACTREC), Tata Memorial Centre, Navi Mumbai, India.; Homi Bhabha National Institute, Training School Complex, Mumbai, India.
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Źródło :
FEBS letters [FEBS Lett] 2021 Nov; Vol. 595 (21), pp. 2675-2690. Date of Electronic Publication: 2021 Oct 23.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
14-3-3 Proteins*
Centrosome*
Desmosomes*
Mitosis*
HCT116 Cells ; Humans ; Spindle Apparatus
Czasopismo naukowe
Tytuł :
Functional reciprocity of proteins involved in mitosis and endocytosis.
Autorzy :
Yu H; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Li Y; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Li L; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Huang J; Department of Genetics, University of Essex, UK.
Wang X; The High School Attached to Hunan Normal University, Changsha, China.
Tang R; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Jiang Z; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.
Lv L; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Chen F; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yu C; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.
Yuan K; Hunan Key Laboratory of Molecular Precision Medicine, Department of Oncology, Xiangya Hospital & Hunan Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, China.; National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, China.; The Biobank of Xiangya Hospital, Central South University, Changsha, China.
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Źródło :
The FEBS journal [FEBS J] 2021 Oct; Vol. 288 (20), pp. 5850-5866. Date of Electronic Publication: 2020 Dec 24.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't; Review
MeSH Terms :
Endocytosis*
Mitosis*
Endosomal Sorting Complexes Required for Transport/*metabolism
Transcription Factors/*metabolism
Animals ; Caveolins/metabolism ; Clathrin/metabolism ; Humans
Czasopismo naukowe
Tytuł :
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex.
Autorzy :
Da Silva F; Division of Molecular Embryology, DKFZ, Heidelberg, Germany.
Zhang K; Division of Molecular Embryology, DKFZ, Heidelberg, Germany.
Pinson A; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Fatti E; Division of Molecular Embryology, DKFZ, Heidelberg, Germany.
Wilsch-Bräuninger M; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Herbst J; Division of Molecular Embryology, DKFZ, Heidelberg, Germany.
Vidal V; INSERM, CNRS, iBV, Université Côte d'Azur, Nice, France.
Schedl A; INSERM, CNRS, iBV, Université Côte d'Azur, Nice, France.
Huttner WB; Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany.
Niehrs C; Division of Molecular Embryology, DKFZ, Heidelberg, Germany.; Institute of Molecular Biology (IMB), Mainz, Germany.
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Źródło :
The EMBO journal [EMBO J] 2021 Oct 01; Vol. 40 (19), pp. e108041. Date of Electronic Publication: 2021 Aug 25.
Typ publikacji :
Journal Article; Research Support, Non-U.S. Gov't
MeSH Terms :
Mitosis*/genetics
Neurogenesis*/genetics
Wnt Signaling Pathway*
Neocortex/*embryology
Neocortex/*metabolism
Amino Acid Sequence ; Animals ; Biomarkers ; Cell Cycle ; Cell Differentiation/genetics ; Cyclins/genetics ; Cyclins/metabolism ; Embryo, Mammalian ; Fluorescent Antibody Technique ; Gene Expression ; Glycogen Synthase Kinase 3/metabolism ; Immunohistochemistry ; Mice ; Mice, Knockout ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Phosphorylation ; SOXC Transcription Factors/genetics ; SOXC Transcription Factors/metabolism
Czasopismo naukowe

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